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Index by author

November 2009; Volume 37,Issue 11

A

  1. Anraku, Makoto

    1. Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
      Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition November 2009, 37 (11) 2197-2203; DOI: https://doi.org/10.1124/dmd.109.028852

B

  1. Baumann, Michael H.

    1. Effects of Dose and Route of Administration on Pharmacokinetics of (±)-3,4-Methylenedioxymethamphetamine in the Rat
      Michael H. Baumann, Dorota Zolkowska, Insook Kim, Karl B. Scheidweiler, Richard B. Rothman and Marilyn A. Huestis
      Drug Metabolism and Disposition November 2009, 37 (11) 2163-2170; DOI: https://doi.org/10.1124/dmd.109.028506

  2. Behanna, Heather A.

    1. Molecular Properties and CYP2D6 Substrates: Central Nervous System Therapeutics Case Study and Pattern Analysis of a Substrate Database
      Laura K. Chico, Heather A. Behanna, Wenhui Hu, Guifa Zhong, Saktimayee Mitra Roy and D. Martin Watterson
      Drug Metabolism and Disposition November 2009, 37 (11) 2204-2211; DOI: https://doi.org/10.1124/dmd.109.028134

  3. Bendaly, Jean

    1. Effect of N-Acetyltransferase 2 Polymorphism on Tumor Target Tissue DNA Adduct Levels in Rapid and Slow Acetylator Congenic Rats Administered 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline
      Kristin J. Metry, Jason R. Neale, Jean Bendaly, Ned B. Smith, William M. Pierce and David W. Hein
      Drug Metabolism and Disposition November 2009, 37 (11) 2123-2126; DOI: https://doi.org/10.1124/dmd.109.029512

  4. Benoit-Biancamano, Marie-Odile

    1. In Vitro Glucuronidation of Fenofibric Acid by Human UDP-Glucuronosyltransferases and Liver Microsomes
      Jelena Tojcic, Marie-Odile Benoit-Biancamano, Michael H. Court, Robert J. Straka, Patrick Caron and Chantal Guillemette
      Drug Metabolism and Disposition November 2009, 37 (11) 2236-2243; DOI: https://doi.org/10.1124/dmd.109.029058

  5. Bloomer, Jackie C.

    1. Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT “Pie”
      Zoe Riches, Emma L. Stanley, Jackie C. Bloomer and Michael W. H. Coughtrie
      Drug Metabolism and Disposition November 2009, 37 (11) 2255-2261; DOI: https://doi.org/10.1124/dmd.109.028399

  6. Bondesson, Ulf

    1. Different Effects of Ketoconazole on the Stereoselective First-Pass Metabolism of R/S-Verapamil in the Intestine and the Liver: Important for the Mechanistic Understanding of First-Pass Drug-Drug Interactions
      Helena Anna Thörn, Mikael Hedeland, Ulf Bondesson, Lars Knutson, Mohammed Yasin, Paul Dickinson and Hans Lennernäs
      Drug Metabolism and Disposition November 2009, 37 (11) 2186-2196; DOI: https://doi.org/10.1124/dmd.109.028027

C

  1. Caron, Patrick

    1. In Vitro Glucuronidation of Fenofibric Acid by Human UDP-Glucuronosyltransferases and Liver Microsomes
      Jelena Tojcic, Marie-Odile Benoit-Biancamano, Michael H. Court, Robert J. Straka, Patrick Caron and Chantal Guillemette
      Drug Metabolism and Disposition November 2009, 37 (11) 2236-2243; DOI: https://doi.org/10.1124/dmd.109.029058

  2. Cheng, Xingguo

    1. Tissue Distribution, Ontogeny, and Hormonal Regulation of Xenobiotic Transporters in Mouse Kidneys
      Xingguo Cheng and Curtis D. Klaassen
      Drug Metabolism and Disposition November 2009, 37 (11) 2178-2185; DOI: https://doi.org/10.1124/dmd.109.027177

  3. Cheng, Y.

    1. Effects of Dose and Route on the Disposition and Kinetics of 1-Butyl-1-methylpyrrolidinium Chloride in Male F-344 Rats
      G. A. Knudsen, Y. Cheng, R. K. Kuester, M. J. Hooth and I. G. Sipes
      Drug Metabolism and Disposition November 2009, 37 (11) 2171-2177; DOI: https://doi.org/10.1124/dmd.109.029082

  4. Chico, Laura K.

    1. Molecular Properties and CYP2D6 Substrates: Central Nervous System Therapeutics Case Study and Pattern Analysis of a Substrate Database
      Laura K. Chico, Heather A. Behanna, Wenhui Hu, Guifa Zhong, Saktimayee Mitra Roy and D. Martin Watterson
      Drug Metabolism and Disposition November 2009, 37 (11) 2204-2211; DOI: https://doi.org/10.1124/dmd.109.028134

  5. Coughtrie, Michael W. H.

    1. Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT “Pie”
      Zoe Riches, Emma L. Stanley, Jackie C. Bloomer and Michael W. H. Coughtrie
      Drug Metabolism and Disposition November 2009, 37 (11) 2255-2261; DOI: https://doi.org/10.1124/dmd.109.028399

  6. Court, Michael H.

    1. In Vitro Glucuronidation of Fenofibric Acid by Human UDP-Glucuronosyltransferases and Liver Microsomes
      Jelena Tojcic, Marie-Odile Benoit-Biancamano, Michael H. Court, Robert J. Straka, Patrick Caron and Chantal Guillemette
      Drug Metabolism and Disposition November 2009, 37 (11) 2236-2243; DOI: https://doi.org/10.1124/dmd.109.029058

D

  1. Delbeke, Frans T.

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

  2. Deventer, Koen

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

  3. Dickinson, Paul

    1. Different Effects of Ketoconazole on the Stereoselective First-Pass Metabolism of R/S-Verapamil in the Intestine and the Liver: Important for the Mechanistic Understanding of First-Pass Drug-Drug Interactions
      Helena Anna Thörn, Mikael Hedeland, Ulf Bondesson, Lars Knutson, Mohammed Yasin, Paul Dickinson and Hans Lennernäs
      Drug Metabolism and Disposition November 2009, 37 (11) 2186-2196; DOI: https://doi.org/10.1124/dmd.109.028027

F

  1. Fardel, Olivier

    1. Differential Regulation of Drug Transporter Expression by Hepatocyte Growth Factor in Primary Human Hepatocytes
      Marc Le Vee, Valérie Lecureur, Amélie Moreau, Bruno Stieger and Olivier Fardel
      Drug Metabolism and Disposition November 2009, 37 (11) 2228-2235; DOI: https://doi.org/10.1124/dmd.109.028035

  2. Farid, Nagy A.

    1. A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel
      Katsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Michiharu Yoshiike, Kokichi Honda, Osamu Okazaki, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition November 2009, 37 (11) 2145-2152; DOI: https://doi.org/10.1124/dmd.109.028498

  3. Finel, Moshe

    1. UDP-Glucuronosyltransferases in Conjugation of 5α- and 5β-Androstane Steroids
      Taina Sten, Mika Kurkela, Tiia Kuuranne, Antti Leinonen and Moshe Finel
      Drug Metabolism and Disposition November 2009, 37 (11) 2221-2227; DOI: https://doi.org/10.1124/dmd.109.029231

  4. Fukamizu, Akiyoshi

    1. Inoculation of Human Tumor Cells Alters the Basal Expression but Not the Inducibility of Cytochrome P450 Enzymes in Tumor-Bearing Mouse Liver
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2244-2254; DOI: https://doi.org/10.1124/dmd.109.028571

G

  1. Guillemette, Chantal

    1. In Vitro Glucuronidation of Fenofibric Acid by Human UDP-Glucuronosyltransferases and Liver Microsomes
      Jelena Tojcic, Marie-Odile Benoit-Biancamano, Michael H. Court, Robert J. Straka, Patrick Caron and Chantal Guillemette
      Drug Metabolism and Disposition November 2009, 37 (11) 2236-2243; DOI: https://doi.org/10.1124/dmd.109.029058

H

  1. Hagihara, Katsunobu

    1. A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel
      Katsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Michiharu Yoshiike, Kokichi Honda, Osamu Okazaki, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition November 2009, 37 (11) 2145-2152; DOI: https://doi.org/10.1124/dmd.109.028498

  2. Hedeland, Mikael

    1. Different Effects of Ketoconazole on the Stereoselective First-Pass Metabolism of R/S-Verapamil in the Intestine and the Liver: Important for the Mechanistic Understanding of First-Pass Drug-Drug Interactions
      Helena Anna Thörn, Mikael Hedeland, Ulf Bondesson, Lars Knutson, Mohammed Yasin, Paul Dickinson and Hans Lennernäs
      Drug Metabolism and Disposition November 2009, 37 (11) 2186-2196; DOI: https://doi.org/10.1124/dmd.109.028027

  3. Hein, David W.

    1. Effect of N-Acetyltransferase 2 Polymorphism on Tumor Target Tissue DNA Adduct Levels in Rapid and Slow Acetylator Congenic Rats Administered 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline
      Kristin J. Metry, Jason R. Neale, Jean Bendaly, Ned B. Smith, William M. Pierce and David W. Hein
      Drug Metabolism and Disposition November 2009, 37 (11) 2123-2126; DOI: https://doi.org/10.1124/dmd.109.029512

  4. Hernández, Felix

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

  5. Honda, Kokichi

    1. A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel
      Katsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Michiharu Yoshiike, Kokichi Honda, Osamu Okazaki, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition November 2009, 37 (11) 2145-2152; DOI: https://doi.org/10.1124/dmd.109.028498

  6. Hooth, M. J.

    1. Effects of Dose and Route on the Disposition and Kinetics of 1-Butyl-1-methylpyrrolidinium Chloride in Male F-344 Rats
      G. A. Knudsen, Y. Cheng, R. K. Kuester, M. J. Hooth and I. G. Sipes
      Drug Metabolism and Disposition November 2009, 37 (11) 2171-2177; DOI: https://doi.org/10.1124/dmd.109.029082

  7. Horinouchi, Hirohisa

    1. Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
      Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition November 2009, 37 (11) 2197-2203; DOI: https://doi.org/10.1124/dmd.109.028852

  8. Hu, Wenhui

    1. Molecular Properties and CYP2D6 Substrates: Central Nervous System Therapeutics Case Study and Pattern Analysis of a Substrate Database
      Laura K. Chico, Heather A. Behanna, Wenhui Hu, Guifa Zhong, Saktimayee Mitra Roy and D. Martin Watterson
      Drug Metabolism and Disposition November 2009, 37 (11) 2204-2211; DOI: https://doi.org/10.1124/dmd.109.028134

  9. Huestis, Marilyn A.

    1. Effects of Dose and Route of Administration on Pharmacokinetics of (±)-3,4-Methylenedioxymethamphetamine in the Rat
      Michael H. Baumann, Dorota Zolkowska, Insook Kim, Karl B. Scheidweiler, Richard B. Rothman and Marilyn A. Huestis
      Drug Metabolism and Disposition November 2009, 37 (11) 2163-2170; DOI: https://doi.org/10.1124/dmd.109.028506

I

  1. Ikeda, Toshihiko

    1. A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel
      Katsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Michiharu Yoshiike, Kokichi Honda, Osamu Okazaki, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition November 2009, 37 (11) 2145-2152; DOI: https://doi.org/10.1124/dmd.109.028498

  2. Iwatsubo, Takafumi

    1. Investigation of Long-Term Retention of Unchanged (−)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, A Novel “Funny” If Current Channel Inhibitor, and Its Metabolites in the Eyeball and Thoracic Aorta of Rats
      Ken-ichi Umehara, Naoyuki Nakada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2137-2144; DOI: https://doi.org/10.1124/dmd.109.027813

K

  1. Kadowaki, Daisuke

    1. Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
      Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition November 2009, 37 (11) 2197-2203; DOI: https://doi.org/10.1124/dmd.109.028852

  2. Kadowaki, Tadashi

    1. Inoculation of Human Tumor Cells Alters the Basal Expression but Not the Inducibility of Cytochrome P450 Enzymes in Tumor-Bearing Mouse Liver
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2244-2254; DOI: https://doi.org/10.1124/dmd.109.028571

  3. Kamimura, Hidetaka

    1. Investigation of Long-Term Retention of Unchanged (−)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, A Novel “Funny” If Current Channel Inhibitor, and Its Metabolites in the Eyeball and Thoracic Aorta of Rats
      Ken-ichi Umehara, Naoyuki Nakada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2137-2144; DOI: https://doi.org/10.1124/dmd.109.027813

  4. Kazui, Miho

    1. A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel
      Katsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Michiharu Yoshiike, Kokichi Honda, Osamu Okazaki, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition November 2009, 37 (11) 2145-2152; DOI: https://doi.org/10.1124/dmd.109.028498

  5. Kelly, Edward J.

    1. Expression and Characterization of CYP4V2 as a Fatty Acid ω-Hydroxylase
      Mariko Nakano, Edward J. Kelly and Allan E. Rettie
      Drug Metabolism and Disposition November 2009, 37 (11) 2119-2122; DOI: https://doi.org/10.1124/dmd.109.028530

  6. Kim, Hyunmi

    1. Identification of New CYP2C19 Variants Exhibiting Decreased Enzyme Activity in the Metabolism of S-Mephenytoin and Omeprazole
      Su-Jun Lee, Woo-Young Kim, Hyunmi Kim, Ji-Hong Shon, Sang Seop Lee and Jae-Gook Shin
      Drug Metabolism and Disposition November 2009, 37 (11) 2262-2269; DOI: https://doi.org/10.1124/dmd.109.028175

  7. Kim, Insook

    1. Effects of Dose and Route of Administration on Pharmacokinetics of (±)-3,4-Methylenedioxymethamphetamine in the Rat
      Michael H. Baumann, Dorota Zolkowska, Insook Kim, Karl B. Scheidweiler, Richard B. Rothman and Marilyn A. Huestis
      Drug Metabolism and Disposition November 2009, 37 (11) 2163-2170; DOI: https://doi.org/10.1124/dmd.109.028506

  8. Kim, Woo-Young

    1. Identification of New CYP2C19 Variants Exhibiting Decreased Enzyme Activity in the Metabolism of S-Mephenytoin and Omeprazole
      Su-Jun Lee, Woo-Young Kim, Hyunmi Kim, Ji-Hong Shon, Sang Seop Lee and Jae-Gook Shin
      Drug Metabolism and Disposition November 2009, 37 (11) 2262-2269; DOI: https://doi.org/10.1124/dmd.109.028175

  9. Klaassen, Curtis D.

    1. Tissue Distribution, Ontogeny, and Hormonal Regulation of Xenobiotic Transporters in Mouse Kidneys
      Xingguo Cheng and Curtis D. Klaassen
      Drug Metabolism and Disposition November 2009, 37 (11) 2178-2185; DOI: https://doi.org/10.1124/dmd.109.027177

  10. Knudsen, G. A.

    1. Effects of Dose and Route on the Disposition and Kinetics of 1-Butyl-1-methylpyrrolidinium Chloride in Male F-344 Rats
      G. A. Knudsen, Y. Cheng, R. K. Kuester, M. J. Hooth and I. G. Sipes
      Drug Metabolism and Disposition November 2009, 37 (11) 2171-2177; DOI: https://doi.org/10.1124/dmd.109.029082

  11. Knutson, Lars

    1. Different Effects of Ketoconazole on the Stereoselective First-Pass Metabolism of R/S-Verapamil in the Intestine and the Liver: Important for the Mechanistic Understanding of First-Pass Drug-Drug Interactions
      Helena Anna Thörn, Mikael Hedeland, Ulf Bondesson, Lars Knutson, Mohammed Yasin, Paul Dickinson and Hans Lennernäs
      Drug Metabolism and Disposition November 2009, 37 (11) 2186-2196; DOI: https://doi.org/10.1124/dmd.109.028027

  12. Kobayashi, Koichi

    1. Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
      Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition November 2009, 37 (11) 2197-2203; DOI: https://doi.org/10.1124/dmd.109.028852

  13. Kozakai, Kazumasa

    1. In Vivo Evaluation of Drug-Drug Interaction via Mechanism-Based Inhibition by Macrolide Antibiotics in Cynomolgus Monkeys
      Akihito Ogasawara, Isao Negishi, Kazumasa Kozakai and Toshiyuki Kume
      Drug Metabolism and Disposition November 2009, 37 (11) 2127-2136; DOI: https://doi.org/10.1124/dmd.109.028969

  14. Kuester, R. K.

    1. Effects of Dose and Route on the Disposition and Kinetics of 1-Butyl-1-methylpyrrolidinium Chloride in Male F-344 Rats
      G. A. Knudsen, Y. Cheng, R. K. Kuester, M. J. Hooth and I. G. Sipes
      Drug Metabolism and Disposition November 2009, 37 (11) 2171-2177; DOI: https://doi.org/10.1124/dmd.109.029082

  15. Kume, Toshiyuki

    1. In Vivo Evaluation of Drug-Drug Interaction via Mechanism-Based Inhibition by Macrolide Antibiotics in Cynomolgus Monkeys
      Akihito Ogasawara, Isao Negishi, Kazumasa Kozakai and Toshiyuki Kume
      Drug Metabolism and Disposition November 2009, 37 (11) 2127-2136; DOI: https://doi.org/10.1124/dmd.109.028969

  16. Kurihara, Atsushi

    1. A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel
      Katsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Michiharu Yoshiike, Kokichi Honda, Osamu Okazaki, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition November 2009, 37 (11) 2145-2152; DOI: https://doi.org/10.1124/dmd.109.028498

  17. Kurkela, Mika

    1. UDP-Glucuronosyltransferases in Conjugation of 5α- and 5β-Androstane Steroids
      Taina Sten, Mika Kurkela, Tiia Kuuranne, Antti Leinonen and Moshe Finel
      Drug Metabolism and Disposition November 2009, 37 (11) 2221-2227; DOI: https://doi.org/10.1124/dmd.109.029231

  18. Kusano, Kazutomi

    1. Inoculation of Human Tumor Cells Alters the Basal Expression but Not the Inducibility of Cytochrome P450 Enzymes in Tumor-Bearing Mouse Liver
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2244-2254; DOI: https://doi.org/10.1124/dmd.109.028571

  19. Kuuranne, Tiia

    1. UDP-Glucuronosyltransferases in Conjugation of 5α- and 5β-Androstane Steroids
      Taina Sten, Mika Kurkela, Tiia Kuuranne, Antti Leinonen and Moshe Finel
      Drug Metabolism and Disposition November 2009, 37 (11) 2221-2227; DOI: https://doi.org/10.1124/dmd.109.029231

L

  1. Lecureur, Valérie

    1. Differential Regulation of Drug Transporter Expression by Hepatocyte Growth Factor in Primary Human Hepatocytes
      Marc Le Vee, Valérie Lecureur, Amélie Moreau, Bruno Stieger and Olivier Fardel
      Drug Metabolism and Disposition November 2009, 37 (11) 2228-2235; DOI: https://doi.org/10.1124/dmd.109.028035

  2. Lee, Sang Seop

    1. Identification of New CYP2C19 Variants Exhibiting Decreased Enzyme Activity in the Metabolism of S-Mephenytoin and Omeprazole
      Su-Jun Lee, Woo-Young Kim, Hyunmi Kim, Ji-Hong Shon, Sang Seop Lee and Jae-Gook Shin
      Drug Metabolism and Disposition November 2009, 37 (11) 2262-2269; DOI: https://doi.org/10.1124/dmd.109.028175

  3. Lee, Su-Jun

    1. Identification of New CYP2C19 Variants Exhibiting Decreased Enzyme Activity in the Metabolism of S-Mephenytoin and Omeprazole
      Su-Jun Lee, Woo-Young Kim, Hyunmi Kim, Ji-Hong Shon, Sang Seop Lee and Jae-Gook Shin
      Drug Metabolism and Disposition November 2009, 37 (11) 2262-2269; DOI: https://doi.org/10.1124/dmd.109.028175

  4. Leinonen, Antti

    1. UDP-Glucuronosyltransferases in Conjugation of 5α- and 5β-Androstane Steroids
      Taina Sten, Mika Kurkela, Tiia Kuuranne, Antti Leinonen and Moshe Finel
      Drug Metabolism and Disposition November 2009, 37 (11) 2221-2227; DOI: https://doi.org/10.1124/dmd.109.029231

  5. Lennernäs, Hans

    1. Different Effects of Ketoconazole on the Stereoselective First-Pass Metabolism of R/S-Verapamil in the Intestine and the Liver: Important for the Mechanistic Understanding of First-Pass Drug-Drug Interactions
      Helena Anna Thörn, Mikael Hedeland, Ulf Bondesson, Lars Knutson, Mohammed Yasin, Paul Dickinson and Hans Lennernäs
      Drug Metabolism and Disposition November 2009, 37 (11) 2186-2196; DOI: https://doi.org/10.1124/dmd.109.028027

  6. Leroux-Roels, Geert

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

  7. Le Vee, Marc

    1. Differential Regulation of Drug Transporter Expression by Hepatocyte Growth Factor in Primary Human Hepatocytes
      Marc Le Vee, Valérie Lecureur, Amélie Moreau, Bruno Stieger and Olivier Fardel
      Drug Metabolism and Disposition November 2009, 37 (11) 2228-2235; DOI: https://doi.org/10.1124/dmd.109.028035

  8. Lootens, Leen

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

M

  1. Maruyama, Toru

    1. Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
      Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition November 2009, 37 (11) 2197-2203; DOI: https://doi.org/10.1124/dmd.109.028852

  2. Maurer, Hans H.

    1. The Role of Human UDP-Glucuronyltransferases on the Formation of the Methylenedioxymethamphetamine (Ecstasy) Phase II Metabolites R- and S-3-Methoxymethamphetamine 4-O-Glucuronides
      Andrea E. Schwaninger, Markus R. Meyer, Josef Zapp and Hans H. Maurer
      Drug Metabolism and Disposition November 2009, 37 (11) 2212-2220; DOI: https://doi.org/10.1124/dmd.109.029215

  3. Metry, Kristin J.

    1. Effect of N-Acetyltransferase 2 Polymorphism on Tumor Target Tissue DNA Adduct Levels in Rapid and Slow Acetylator Congenic Rats Administered 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline
      Kristin J. Metry, Jason R. Neale, Jean Bendaly, Ned B. Smith, William M. Pierce and David W. Hein
      Drug Metabolism and Disposition November 2009, 37 (11) 2123-2126; DOI: https://doi.org/10.1124/dmd.109.029512

  4. Meuleman, Philip

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

  5. Meyer, Markus R.

    1. The Role of Human UDP-Glucuronyltransferases on the Formation of the Methylenedioxymethamphetamine (Ecstasy) Phase II Metabolites R- and S-3-Methoxymethamphetamine 4-O-Glucuronides
      Andrea E. Schwaninger, Markus R. Meyer, Josef Zapp and Hans H. Maurer
      Drug Metabolism and Disposition November 2009, 37 (11) 2212-2220; DOI: https://doi.org/10.1124/dmd.109.029215

  6. Moreau, Amélie

    1. Differential Regulation of Drug Transporter Expression by Hepatocyte Growth Factor in Primary Human Hepatocytes
      Marc Le Vee, Valérie Lecureur, Amélie Moreau, Bruno Stieger and Olivier Fardel
      Drug Metabolism and Disposition November 2009, 37 (11) 2228-2235; DOI: https://doi.org/10.1124/dmd.109.028035

N

  1. Nakada, Naoyuki

    1. Investigation of Long-Term Retention of Unchanged (−)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, A Novel “Funny” If Current Channel Inhibitor, and Its Metabolites in the Eyeball and Thoracic Aorta of Rats
      Ken-ichi Umehara, Naoyuki Nakada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2137-2144; DOI: https://doi.org/10.1124/dmd.109.027813

  2. Nakano, Mariko

    1. Expression and Characterization of CYP4V2 as a Fatty Acid ω-Hydroxylase
      Mariko Nakano, Edward J. Kelly and Allan E. Rettie
      Drug Metabolism and Disposition November 2009, 37 (11) 2119-2122; DOI: https://doi.org/10.1124/dmd.109.028530

  3. Neale, Jason R.

    1. Effect of N-Acetyltransferase 2 Polymorphism on Tumor Target Tissue DNA Adduct Levels in Rapid and Slow Acetylator Congenic Rats Administered 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline
      Kristin J. Metry, Jason R. Neale, Jean Bendaly, Ned B. Smith, William M. Pierce and David W. Hein
      Drug Metabolism and Disposition November 2009, 37 (11) 2123-2126; DOI: https://doi.org/10.1124/dmd.109.029512

  4. Negishi, Isao

    1. In Vivo Evaluation of Drug-Drug Interaction via Mechanism-Based Inhibition by Macrolide Antibiotics in Cynomolgus Monkeys
      Akihito Ogasawara, Isao Negishi, Kazumasa Kozakai and Toshiyuki Kume
      Drug Metabolism and Disposition November 2009, 37 (11) 2127-2136; DOI: https://doi.org/10.1124/dmd.109.028969

  5. Noguchi, Kiyoshi

    1. Investigation of Long-Term Retention of Unchanged (−)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, A Novel “Funny” If Current Channel Inhibitor, and Its Metabolites in the Eyeball and Thoracic Aorta of Rats
      Ken-ichi Umehara, Naoyuki Nakada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2137-2144; DOI: https://doi.org/10.1124/dmd.109.027813

O

  1. Ogasawara, Akihito

    1. In Vivo Evaluation of Drug-Drug Interaction via Mechanism-Based Inhibition by Macrolide Antibiotics in Cynomolgus Monkeys
      Akihito Ogasawara, Isao Negishi, Kazumasa Kozakai and Toshiyuki Kume
      Drug Metabolism and Disposition November 2009, 37 (11) 2127-2136; DOI: https://doi.org/10.1124/dmd.109.028969

  2. Okamoto, Kiyoshi

    1. Inoculation of Human Tumor Cells Alters the Basal Expression but Not the Inducibility of Cytochrome P450 Enzymes in Tumor-Bearing Mouse Liver
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2244-2254; DOI: https://doi.org/10.1124/dmd.109.028571

  3. Okazaki, Osamu

    1. A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel
      Katsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Michiharu Yoshiike, Kokichi Honda, Osamu Okazaki, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition November 2009, 37 (11) 2145-2152; DOI: https://doi.org/10.1124/dmd.109.028498

  4. Otagiri, Masaki

    1. Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
      Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition November 2009, 37 (11) 2197-2203; DOI: https://doi.org/10.1124/dmd.109.028852

P

  1. Parr, Maria K.

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

  2. Pierce, William M.

    1. Effect of N-Acetyltransferase 2 Polymorphism on Tumor Target Tissue DNA Adduct Levels in Rapid and Slow Acetylator Congenic Rats Administered 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline
      Kristin J. Metry, Jason R. Neale, Jean Bendaly, Ned B. Smith, William M. Pierce and David W. Hein
      Drug Metabolism and Disposition November 2009, 37 (11) 2123-2126; DOI: https://doi.org/10.1124/dmd.109.029512

  3. Pozo, Óscar J.

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

R

  1. Rettie, Allan E.

    1. Expression and Characterization of CYP4V2 as a Fatty Acid ω-Hydroxylase
      Mariko Nakano, Edward J. Kelly and Allan E. Rettie
      Drug Metabolism and Disposition November 2009, 37 (11) 2119-2122; DOI: https://doi.org/10.1124/dmd.109.028530

  2. Riches, Zoe

    1. Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT “Pie”
      Zoe Riches, Emma L. Stanley, Jackie C. Bloomer and Michael W. H. Coughtrie
      Drug Metabolism and Disposition November 2009, 37 (11) 2255-2261; DOI: https://doi.org/10.1124/dmd.109.028399

  3. Rothman, Richard B.

    1. Effects of Dose and Route of Administration on Pharmacokinetics of (±)-3,4-Methylenedioxymethamphetamine in the Rat
      Michael H. Baumann, Dorota Zolkowska, Insook Kim, Karl B. Scheidweiler, Richard B. Rothman and Marilyn A. Huestis
      Drug Metabolism and Disposition November 2009, 37 (11) 2163-2170; DOI: https://doi.org/10.1124/dmd.109.028506

  4. Roy, Saktimayee Mitra

    1. Molecular Properties and CYP2D6 Substrates: Central Nervous System Therapeutics Case Study and Pattern Analysis of a Substrate Database
      Laura K. Chico, Heather A. Behanna, Wenhui Hu, Guifa Zhong, Saktimayee Mitra Roy and D. Martin Watterson
      Drug Metabolism and Disposition November 2009, 37 (11) 2204-2211; DOI: https://doi.org/10.1124/dmd.109.028134

S

  1. Sakai, Hiromi

    1. Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
      Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition November 2009, 37 (11) 2197-2203; DOI: https://doi.org/10.1124/dmd.109.028852

  2. Sancho, Juan V.

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

  3. Schänzer, Wilhelm

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

  4. Scheidweiler, Karl B.

    1. Effects of Dose and Route of Administration on Pharmacokinetics of (±)-3,4-Methylenedioxymethamphetamine in the Rat
      Michael H. Baumann, Dorota Zolkowska, Insook Kim, Karl B. Scheidweiler, Richard B. Rothman and Marilyn A. Huestis
      Drug Metabolism and Disposition November 2009, 37 (11) 2163-2170; DOI: https://doi.org/10.1124/dmd.109.028506

  5. Schwaninger, Andrea E.

    1. The Role of Human UDP-Glucuronyltransferases on the Formation of the Methylenedioxymethamphetamine (Ecstasy) Phase II Metabolites R- and S-3-Methoxymethamphetamine 4-O-Glucuronides
      Andrea E. Schwaninger, Markus R. Meyer, Josef Zapp and Hans H. Maurer
      Drug Metabolism and Disposition November 2009, 37 (11) 2212-2220; DOI: https://doi.org/10.1124/dmd.109.029215

  6. Shin, Jae-Gook

    1. Identification of New CYP2C19 Variants Exhibiting Decreased Enzyme Activity in the Metabolism of S-Mephenytoin and Omeprazole
      Su-Jun Lee, Woo-Young Kim, Hyunmi Kim, Ji-Hong Shon, Sang Seop Lee and Jae-Gook Shin
      Drug Metabolism and Disposition November 2009, 37 (11) 2262-2269; DOI: https://doi.org/10.1124/dmd.109.028175

  7. Shon, Ji-Hong

    1. Identification of New CYP2C19 Variants Exhibiting Decreased Enzyme Activity in the Metabolism of S-Mephenytoin and Omeprazole
      Su-Jun Lee, Woo-Young Kim, Hyunmi Kim, Ji-Hong Shon, Sang Seop Lee and Jae-Gook Shin
      Drug Metabolism and Disposition November 2009, 37 (11) 2262-2269; DOI: https://doi.org/10.1124/dmd.109.028175

  8. Sipes, I. G.

    1. Effects of Dose and Route on the Disposition and Kinetics of 1-Butyl-1-methylpyrrolidinium Chloride in Male F-344 Rats
      G. A. Knudsen, Y. Cheng, R. K. Kuester, M. J. Hooth and I. G. Sipes
      Drug Metabolism and Disposition November 2009, 37 (11) 2171-2177; DOI: https://doi.org/10.1124/dmd.109.029082

  9. Smith, Ned B.

    1. Effect of N-Acetyltransferase 2 Polymorphism on Tumor Target Tissue DNA Adduct Levels in Rapid and Slow Acetylator Congenic Rats Administered 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline
      Kristin J. Metry, Jason R. Neale, Jean Bendaly, Ned B. Smith, William M. Pierce and David W. Hein
      Drug Metabolism and Disposition November 2009, 37 (11) 2123-2126; DOI: https://doi.org/10.1124/dmd.109.029512

  10. Stanley, Emma L.

    1. Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT “Pie”
      Zoe Riches, Emma L. Stanley, Jackie C. Bloomer and Michael W. H. Coughtrie
      Drug Metabolism and Disposition November 2009, 37 (11) 2255-2261; DOI: https://doi.org/10.1124/dmd.109.028399

  11. Sten, Taina

    1. UDP-Glucuronosyltransferases in Conjugation of 5α- and 5β-Androstane Steroids
      Taina Sten, Mika Kurkela, Tiia Kuuranne, Antti Leinonen and Moshe Finel
      Drug Metabolism and Disposition November 2009, 37 (11) 2221-2227; DOI: https://doi.org/10.1124/dmd.109.029231

  12. Stieger, Bruno

    1. Differential Regulation of Drug Transporter Expression by Hepatocyte Growth Factor in Primary Human Hepatocytes
      Marc Le Vee, Valérie Lecureur, Amélie Moreau, Bruno Stieger and Olivier Fardel
      Drug Metabolism and Disposition November 2009, 37 (11) 2228-2235; DOI: https://doi.org/10.1124/dmd.109.028035

  13. Straka, Robert J.

    1. In Vitro Glucuronidation of Fenofibric Acid by Human UDP-Glucuronosyltransferases and Liver Microsomes
      Jelena Tojcic, Marie-Odile Benoit-Biancamano, Michael H. Court, Robert J. Straka, Patrick Caron and Chantal Guillemette
      Drug Metabolism and Disposition November 2009, 37 (11) 2236-2243; DOI: https://doi.org/10.1124/dmd.109.029058

  14. Sugawara, Michiko

    1. Inoculation of Human Tumor Cells Alters the Basal Expression but Not the Inducibility of Cytochrome P450 Enzymes in Tumor-Bearing Mouse Liver
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2244-2254; DOI: https://doi.org/10.1124/dmd.109.028571

T

  1. Taguchi, Kazuaki

    1. Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
      Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition November 2009, 37 (11) 2197-2203; DOI: https://doi.org/10.1124/dmd.109.028852

  2. Thörn, Helena Anna

    1. Different Effects of Ketoconazole on the Stereoselective First-Pass Metabolism of R/S-Verapamil in the Intestine and the Liver: Important for the Mechanistic Understanding of First-Pass Drug-Drug Interactions
      Helena Anna Thörn, Mikael Hedeland, Ulf Bondesson, Lars Knutson, Mohammed Yasin, Paul Dickinson and Hans Lennernäs
      Drug Metabolism and Disposition November 2009, 37 (11) 2186-2196; DOI: https://doi.org/10.1124/dmd.109.028027

  3. Tojcic, Jelena

    1. In Vitro Glucuronidation of Fenofibric Acid by Human UDP-Glucuronosyltransferases and Liver Microsomes
      Jelena Tojcic, Marie-Odile Benoit-Biancamano, Michael H. Court, Robert J. Straka, Patrick Caron and Chantal Guillemette
      Drug Metabolism and Disposition November 2009, 37 (11) 2236-2243; DOI: https://doi.org/10.1124/dmd.109.029058

  4. Tsuchida, Eishun

    1. Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
      Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition November 2009, 37 (11) 2197-2203; DOI: https://doi.org/10.1124/dmd.109.028852

U

  1. Umehara, Ken-ichi

    1. Investigation of Long-Term Retention of Unchanged (−)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, A Novel “Funny” If Current Channel Inhibitor, and Its Metabolites in the Eyeball and Thoracic Aorta of Rats
      Ken-ichi Umehara, Naoyuki Nakada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2137-2144; DOI: https://doi.org/10.1124/dmd.109.027813

  2. Urata, Yukino

    1. Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
      Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition November 2009, 37 (11) 2197-2203; DOI: https://doi.org/10.1124/dmd.109.028852

  3. Usui, Takashi

    1. Investigation of Long-Term Retention of Unchanged (−)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, A Novel “Funny” If Current Channel Inhibitor, and Its Metabolites in the Eyeball and Thoracic Aorta of Rats
      Ken-ichi Umehara, Naoyuki Nakada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2137-2144; DOI: https://doi.org/10.1124/dmd.109.027813

V

  1. Van Eenoo, Peter

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

  2. Van Thuyne, Wim

    1. Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
      Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels and Frans T. Delbeke
      Drug Metabolism and Disposition November 2009, 37 (11) 2153-2162; DOI: https://doi.org/10.1124/dmd.109.028373

W

  1. Watanabe, Hiroshi

    1. Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
      Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition November 2009, 37 (11) 2197-2203; DOI: https://doi.org/10.1124/dmd.109.028852

  2. Watterson, D. Martin

    1. Molecular Properties and CYP2D6 Substrates: Central Nervous System Therapeutics Case Study and Pattern Analysis of a Substrate Database
      Laura K. Chico, Heather A. Behanna, Wenhui Hu, Guifa Zhong, Saktimayee Mitra Roy and D. Martin Watterson
      Drug Metabolism and Disposition November 2009, 37 (11) 2204-2211; DOI: https://doi.org/10.1124/dmd.109.028134

Y

  1. Yasin, Mohammed

    1. Different Effects of Ketoconazole on the Stereoselective First-Pass Metabolism of R/S-Verapamil in the Intestine and the Liver: Important for the Mechanistic Understanding of First-Pass Drug-Drug Interactions
      Helena Anna Thörn, Mikael Hedeland, Ulf Bondesson, Lars Knutson, Mohammed Yasin, Paul Dickinson and Hans Lennernäs
      Drug Metabolism and Disposition November 2009, 37 (11) 2186-2196; DOI: https://doi.org/10.1124/dmd.109.028027

  2. Yoshiike, Michiharu

    1. A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel
      Katsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Michiharu Yoshiike, Kokichi Honda, Osamu Okazaki, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition November 2009, 37 (11) 2145-2152; DOI: https://doi.org/10.1124/dmd.109.028498

  3. Yoshimura, Tsutomu

    1. Inoculation of Human Tumor Cells Alters the Basal Expression but Not the Inducibility of Cytochrome P450 Enzymes in Tumor-Bearing Mouse Liver
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition November 2009, 37 (11) 2244-2254; DOI: https://doi.org/10.1124/dmd.109.028571

Z

  1. Zapp, Josef

    1. The Role of Human UDP-Glucuronyltransferases on the Formation of the Methylenedioxymethamphetamine (Ecstasy) Phase II Metabolites R- and S-3-Methoxymethamphetamine 4-O-Glucuronides
      Andrea E. Schwaninger, Markus R. Meyer, Josef Zapp and Hans H. Maurer
      Drug Metabolism and Disposition November 2009, 37 (11) 2212-2220; DOI: https://doi.org/10.1124/dmd.109.029215

  2. Zhong, Guifa

    1. Molecular Properties and CYP2D6 Substrates: Central Nervous System Therapeutics Case Study and Pattern Analysis of a Substrate Database
      Laura K. Chico, Heather A. Behanna, Wenhui Hu, Guifa Zhong, Saktimayee Mitra Roy and D. Martin Watterson
      Drug Metabolism and Disposition November 2009, 37 (11) 2204-2211; DOI: https://doi.org/10.1124/dmd.109.028134

  3. Zolkowska, Dorota

    1. Effects of Dose and Route of Administration on Pharmacokinetics of (±)-3,4-Methylenedioxymethamphetamine in the Rat
      Michael H. Baumann, Dorota Zolkowska, Insook Kim, Karl B. Scheidweiler, Richard B. Rothman and Marilyn A. Huestis
      Drug Metabolism and Disposition November 2009, 37 (11) 2163-2170; DOI: https://doi.org/10.1124/dmd.109.028506
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