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Research ArticleArticle

Evaluation of the Potential for Drug-Induced Liver Injury Based on in Vitro Covalent Binding to Human Liver Proteins

Toru Usui, Masashi Mise, Takanori Hashizume, Masashi Yabuki and Setsuko Komuro
Drug Metabolism and Disposition December 2009, 37 (12) 2383-2392; DOI: https://doi.org/10.1124/dmd.109.028860

Article Information

vol. 37 no. 12 2383-2392
DOI 
https://doi.org/10.1124/dmd.109.028860
PubMed 
19720731
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 9, 2009
  • Accepted August 27, 2009
  • Published online November 19, 2009.

Article Versions

Copyright & Usage 
Copyright © 2009 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Toru Usui,
  2. Masashi Mise,
  3. Takanori Hashizume,
  4. Masashi Yabuki and
  5. Setsuko Komuro
  1. Pharmacokinetics Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., Kasugade-naka, Konohana-ku, Osaka, Japan
  1. Address correspondence to:
    Dr. Takanori Hashizume,
    Pharmacokinetics Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 3-1-98, Kasugade-naka, Konohana-ku, Osaka, 554-0022, Japan.
    E-mail: takanori-hashizume{at}ds-pharma.co.jp
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Research ArticleArticle

Evaluation of the Potential for Drug-Induced Liver Injury Based on in Vitro Covalent Binding to Human Liver Proteins

Toru Usui, Masashi Mise, Takanori Hashizume, Masashi Yabuki and Setsuko Komuro
Drug Metabolism and Disposition December 1, 2009, 37 (12) 2383-2392; DOI: https://doi.org/10.1124/dmd.109.028860
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