Table of Contents

Articles

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  Induction of CYP4F3 by Benzene Metabolites in Human White Blood Cells in Vivo in Human Promyelocytic Leukemic Cell Lines and ex Vivo in Human Blood Neutrophils

  Zhiwei Zhao, Xiaoqing He, Yongyi Bi, Ying Xia, Ning Tao, Li Li and Qiang Ma

  Drug Metabolism and Disposition February 2009, 37 (2) 282-291; DOI: https://doi.org/10.1124/dmd.108.023192
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  Identification and Quantitation of the N-Acetyl-L-cysteine S-Conjugates of Bendamustine and Its Sulfoxides in Human Bile after Administration of Bendamustine Hydrochloride

  Jens Teichert, Reinhard Sohr, Lothar Hennig, Frank Baumann, Konrad Schoppmeyer, Ulrich Patzak and Rainer Preiss

  Drug Metabolism and Disposition February 2009, 37 (2) 292-301; DOI: https://doi.org/10.1124/dmd.108.022855
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  Recombinant Zebrafish γ-Glutamyl Hydrolase Exhibits Properties and Catalytic Activities Comparable with Those of Mammalian Enzyme

  Tseng-Ting Kao, Wen-Ni Chang, Hua-Lin Wu, Guey-Yueh Shi and Tzu-Fun Fu

  Drug Metabolism and Disposition February 2009, 37 (2) 302-309; DOI: https://doi.org/10.1124/dmd.108.024042
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  Pharmacodynamic Evaluation of the Cardiovascular Effects after the Coadministration of Cocaine and Ethanol

  S. Casey Laizure and Robert B. Parker

  Drug Metabolism and Disposition February 2009, 37 (2) 310-314; DOI: https://doi.org/10.1124/dmd.108.023531
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  Limited Brain Distribution of [3R,4R,5S]-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate Phosphate (Ro 64-0802), a Pharmacologically Active Form of Oseltamivir, by Active Efflux across the Blood-Brain Barrier Mediated by Organic Anion Transporter 3 (Oat3/Slc22a8) and Multidrug Resistance-Associated Protein 4 (Mrp4/Abcc4)

  Atsushi Ose, Mototsugu Ito, Hiroyuki Kusuhara, Kenzo Yamatsugu, Motomu Kanai, Masakatsu Shibasaki, Masakiyo Hosokawa, John D. Schuetz and Yuichi Sugiyama

  Drug Metabolism and Disposition February 2009, 37 (2) 315-321; DOI: https://doi.org/10.1124/dmd.108.024018
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  Deferiprone Glucuronidation by Human Tissues and Recombinant UDP Glucuronosyltransferase 1A6: An in Vitro Investigation of Genetic and Splice Variants

  Marie-Odile Benoit-Biancamano, John Connelly, Lyne Villeneuve, Patrick Caron and Chantal Guillemette

  Drug Metabolism and Disposition February 2009, 37 (2) 322-329; DOI: https://doi.org/10.1124/dmd.108.023101
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  The Carnitine Transporter SLC22A5 Is Not a General Drug Transporter, but It Efficiently Translocates Mildronate

  Silke Grigat, Christian Fork, Markus Bach, Stefan Golz, Andreas Geerts, Edgar Schömig and Dirk Gründemann

  Drug Metabolism and Disposition February 2009, 37 (2) 330-337; DOI: https://doi.org/10.1124/dmd.108.023929
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  Cholesterol Feeding Prevents Hepatic Accumulation of Bile Acids in Cholic Acid-Fed Farnesoid X Receptor (FXR)-Null Mice: FXR-Independent Suppression of Intestinal Bile Acid Absorption

  Masaaki Miyata, Yoshiki Matsuda, Masahiro Nomoto, Yuki Takamatsu, Nozomi Sato, Mayumi Hamatsu, Paul A. Dawson, Frank J. Gonzalez and Yasushi Yamazoe

  Drug Metabolism and Disposition February 2009, 37 (2) 338-344; DOI: https://doi.org/10.1124/dmd.108.022590
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  Metabolic Activation of Benzodiazepines by CYP3A4

  Katsuhiko Mizuno, Miki Katoh, Hirotoshi Okumura, Nao Nakagawa, Toru Negishi, Takanori Hashizume, Miki Nakajima and Tsuyoshi Yokoi

  Drug Metabolism and Disposition February 2009, 37 (2) 345-351; DOI: https://doi.org/10.1124/dmd.108.024521
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  Determination of Trimethylbismuth in the Human Body after Ingestion of Colloidal Bismuth Subcitrate

  Jens Boertz, Louise Michele Hartmann, Margareta Sulkowski, Joerg Hippler, Frank Mosel, Roland Arturo Diaz-Bone, Klaus Michalke, Albert Wolfgang Rettenmeier and Alfred Vitalis Hirner

  Drug Metabolism and Disposition February 2009, 37 (2) 352-358; DOI: https://doi.org/10.1124/dmd.107.020313
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  Sunitinib (Sutent, SU11248), a Small-Molecule Receptor Tyrosine Kinase Inhibitor, Blocks Function of the ATP-Binding Cassette (ABC) Transporters P-Glycoprotein (ABCB1) and ABCG2

  Suneet Shukla, Robert W. Robey, Susan E. Bates and Suresh V. Ambudkar

  Drug Metabolism and Disposition February 2009, 37 (2) 359-365; DOI: https://doi.org/10.1124/dmd.108.024612
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  Regulation of Hepatic Cytochrome P450 Expression in Mice with Intestinal or Systemic Infections of Citrobacter rodentium

  Madhusudana R. Chaluvadi, Ryan D. Kinloch, Beatrice A. Nyagode, Terrilyn A. Richardson, Malik J. Raynor, Melanie Sherman, Leposava Antonovic, Henry W. Strobel, Dirck L. Dillehay and Edward T. Morgan

  Drug Metabolism and Disposition February 2009, 37 (2) 366-374; DOI: https://doi.org/10.1124/dmd.108.024240
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  Drug Interaction Potential of 2-((3,4-Dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the Novel Nonstatin-Type Cholesterol-Lowering Agent

  Katalin Monostory, Jean-Marc Pascussi, Pál Szabó, Manna Temesvári, Krisztina Köhalmy, Jure Acimovic, Darko Kocjan, Drago Kuzman, Britta Wilzewski, Rita Bernhardt, László Kóbori and Damjana Rozman

  Drug Metabolism and Disposition February 2009, 37 (2) 375-385; DOI: https://doi.org/10.1124/dmd.108.023887
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  Relationship between Drug/Metabolite Exposure and Impairment of Excretory Transport Function

  Maciej J. Zamek-Gliszczynski, J. Cory Kalvass, Gary M. Pollack and Kim L. R. Brouwer

  Drug Metabolism and Disposition February 2009, 37 (2) 386-390; DOI: https://doi.org/10.1124/dmd.108.023648
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  In Silico and in Vitro Modeling of Hepatocyte Drug Transport Processes: Importance of ABCC2 Expression Levels in the Disposition of Carboxydichlorofluroscein

  Katharine Howe, G. Gordon Gibson, Tanya Coleman and Nick Plant

  Drug Metabolism and Disposition February 2009, 37 (2) 391-399; DOI: https://doi.org/10.1124/dmd.108.022921
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  Pharmacogenetics of Human Carbonyl Reductase 1 (CBR1) in Livers from Black and White Donors

  Vanessa Gonzalez-Covarrubias, Jianping Zhang, James L. Kalabus, Mary V. Relling and Javier G. Blanco

  Drug Metabolism and Disposition February 2009, 37 (2) 400-407; DOI: https://doi.org/10.1124/dmd.108.024547
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  Absorption, Distribution, Metabolism, and Excretion of 2,2-Bis(bromomethyl)-1,3-propanediol in Male Fischer-344 Rats

  Simone I. Hoehle, Gabriel A. Knudsen, J. Michael Sanders and I. Glenn Sipes

  Drug Metabolism and Disposition February 2009, 37 (2) 408-416; DOI: https://doi.org/10.1124/dmd.108.023937
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  UDP-Glucuronosyltransferases (UGTs) 2B7 and UGT2B17 Display Converse Specificity in Testosterone and Epitestosterone Glucuronidation, whereas UGT2A1 Conjugates Both Androgens Similarly

  Taina Sten, Ingo Bichlmaier, Tiia Kuuranne, Antti Leinonen, Jari Yli-Kauhaluoma and Moshe Finel

  Drug Metabolism and Disposition February 2009, 37 (2) 417-423; DOI: https://doi.org/10.1124/dmd.108.024844
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  Transport of Dicationic Drugs Pentamidine and Furamidine by Human Organic Cation Transporters

  Xin Ming, Wujian Ju, Huali Wu, Richard R. Tidwell, James E. Hall and Dhiren R. Thakker

  Drug Metabolism and Disposition February 2009, 37 (2) 424-430; DOI: https://doi.org/10.1124/dmd.108.024083
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  Metabolism of Echinacoside, a Good Antioxidant, in Rats: Isolation and Identification of Its Biliary Metabolites

  Cunqin Jia, Haiming Shi, Wei Jin, Ke Zhang, Yong Jiang, Mingbo Zhao and Pengfei Tu

  Drug Metabolism and Disposition February 2009, 37 (2) 431-438; DOI: https://doi.org/10.1124/dmd.108.023697