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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

March 01, 2009; Volume 37,Issue 3
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abe, Koji

    1. You have access
      Use of Sandwich-Cultured Human Hepatocytes to Predict Biliary Clearance of Angiotensin II Receptor Blockers and HMG-CoA Reductase Inhibitors
      Koji Abe, Arlene S. Bridges and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2009, 37 (3) 447-452; DOI: https://doi.org/10.1124/dmd.108.023465
  2. Agarwal, Sagar

    1. You have access
      Substrate-Dependent Breast Cancer Resistance Protein (Bcrp1/Abcg2)-Mediated Interactions: Consideration of Multiple Binding Sites in in Vitro Assay Design
      Nagdeep Giri, Sagar Agarwal, Naveed Shaik, Guoyu Pan, Ying Chen and William F. Elmquist
      Drug Metabolism and Disposition March 2009, 37 (3) 560-570; DOI: https://doi.org/10.1124/dmd.108.022046
  3. Allen, Darin

    1. You have access
      Metabolism of (+)-1,4-Dihydro-7-(trans-3-methoxy-4-methylamino-1-pyrrolidinyl)-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic Acid (Voreloxin; Formerly SNS-595), a Novel Replication-Dependent DNA-Damaging Agent
      Marc J. Evanchik, Darin Allen, Josh C. Yoburn, Jeffrey A. Silverman and Ute Hoch
      Drug Metabolism and Disposition March 2009, 37 (3) 594-601; DOI: https://doi.org/10.1124/dmd.108.023432
  4. Anderson, Alan

    1. You have access
      Dexamethasone Induction of Murine CYP2B Genes Requires the Glucocorticoid Receptor
      Étienne Audet-Walsh and Alan Anderson
      Drug Metabolism and Disposition March 2009, 37 (3) 580-588; DOI: https://doi.org/10.1124/dmd.108.022772
  5. Audet-Walsh, Étienne

    1. You have access
      Dexamethasone Induction of Murine CYP2B Genes Requires the Glucocorticoid Receptor
      Étienne Audet-Walsh and Alan Anderson
      Drug Metabolism and Disposition March 2009, 37 (3) 580-588; DOI: https://doi.org/10.1124/dmd.108.022772

B

  1. Bandiera, Stelvio M.

    1. You have access
      Developmental Expression and Endocrine Regulation of CYP1B1 in Rat Testis
      Grace S. Leung, Masahiko Kawai, Jenny K. Tai, Jie Chen, Stelvio M. Bandiera and Thomas K. H. Chang
      Drug Metabolism and Disposition March 2009, 37 (3) 523-528; DOI: https://doi.org/10.1124/dmd.108.025635
  2. Batard, Yannick

    1. You have access
      Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Yannick Batard, Lai Wang, Heidi Einolf, Helen Gu, James B. Mangold, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 536-544; DOI: https://doi.org/10.1124/dmd.108.023010
  3. Bednarski, Patrick J.

    1. You have access
      Investigation of the in Vitro Metabolism of the Analgesic Flupirtine
      Karen Methling, Przyemslaw Reszka, Michael Lalk, Oldrich Vrana, Eberhard Scheuch, Werner Siegmund, Bernd Terhaag and Patrick J. Bednarski
      Drug Metabolism and Disposition March 2009, 37 (3) 479-493; DOI: https://doi.org/10.1124/dmd.108.024364
  4. Berg, Jeannette Zinggeler

    1. You have access
      Effect of CYP2A13 Active Site Mutation N297A on Metabolism of Coumarin and Tobacco-Specific Nitrosamines
      Kari E. Schlicht, Jeannette Zinggeler Berg and Sharon E. Murphy
      Drug Metabolism and Disposition March 2009, 37 (3) 665-671; DOI: https://doi.org/10.1124/dmd.108.025072
  5. Berry, Karen

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  6. Bridges, Arlene S.

    1. You have access
      Use of Sandwich-Cultured Human Hepatocytes to Predict Biliary Clearance of Angiotensin II Receptor Blockers and HMG-CoA Reductase Inhibitors
      Koji Abe, Arlene S. Bridges and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2009, 37 (3) 447-452; DOI: https://doi.org/10.1124/dmd.108.023465
    2. You have access
      Fexofenadine Brain Exposure and the Influence of Blood-Brain Barrier P-Glycoprotein After Fexofenadine and Terfenadine Administration
      Rong Zhao, J. Cory Kalvass, Souzan B. Yanni, Arlene S. Bridges and Gary M. Pollack
      Drug Metabolism and Disposition March 2009, 37 (3) 529-535; DOI: https://doi.org/10.1124/dmd.107.019893
  7. Brouwer, Kim L. R.

    1. You have access
      Use of Sandwich-Cultured Human Hepatocytes to Predict Biliary Clearance of Angiotensin II Receptor Blockers and HMG-CoA Reductase Inhibitors
      Koji Abe, Arlene S. Bridges and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2009, 37 (3) 447-452; DOI: https://doi.org/10.1124/dmd.108.023465

C

  1. Carrizosa, Daniel R.

    1. You have access
      Identification of a Cranberry Juice Product that Inhibits Enteric CYP3A-Mediated First-Pass Metabolism in Humans
      Ngoc Ngo, Zhixia Yan, Tyler N. Graf, Daniel R. Carrizosa, Angela D. M. Kashuba, E. Claire Dees, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition March 2009, 37 (3) 514-522; DOI: https://doi.org/10.1124/dmd.108.024968
  2. Cashman, John R.

    1. You have access
      Hepatic Flavin-Containing Monooxygenase Gene Regulation in Different Mouse Inflammation Models
      Jun Zhang, Madhusudana R. Chaluvadi, Rob Reddy, Meike S. Motika, Terrilyn A. Richardson, John R. Cashman and Edward T. Morgan
      Drug Metabolism and Disposition March 2009, 37 (3) 462-468; DOI: https://doi.org/10.1124/dmd.108.025338
  3. Chaluvadi, Madhusudana R.

    1. You have access
      Hepatic Flavin-Containing Monooxygenase Gene Regulation in Different Mouse Inflammation Models
      Jun Zhang, Madhusudana R. Chaluvadi, Rob Reddy, Meike S. Motika, Terrilyn A. Richardson, John R. Cashman and Edward T. Morgan
      Drug Metabolism and Disposition March 2009, 37 (3) 462-468; DOI: https://doi.org/10.1124/dmd.108.025338
  4. Chang, Thomas K. H.

    1. You have access
      Developmental Expression and Endocrine Regulation of CYP1B1 in Rat Testis
      Grace S. Leung, Masahiko Kawai, Jenny K. Tai, Jie Chen, Stelvio M. Bandiera and Thomas K. H. Chang
      Drug Metabolism and Disposition March 2009, 37 (3) 523-528; DOI: https://doi.org/10.1124/dmd.108.025635
  5. Chen, Jie

    1. You have access
      Developmental Expression and Endocrine Regulation of CYP1B1 in Rat Testis
      Grace S. Leung, Masahiko Kawai, Jenny K. Tai, Jie Chen, Stelvio M. Bandiera and Thomas K. H. Chang
      Drug Metabolism and Disposition March 2009, 37 (3) 523-528; DOI: https://doi.org/10.1124/dmd.108.025635
  6. Chen, Ying

    1. You have access
      Substrate-Dependent Breast Cancer Resistance Protein (Bcrp1/Abcg2)-Mediated Interactions: Consideration of Multiple Binding Sites in in Vitro Assay Design
      Nagdeep Giri, Sagar Agarwal, Naveed Shaik, Guoyu Pan, Ying Chen and William F. Elmquist
      Drug Metabolism and Disposition March 2009, 37 (3) 560-570; DOI: https://doi.org/10.1124/dmd.108.022046
  7. Chiang, John Y. L.

    1. You have access
      Mechanism of Vitamin D Receptor Inhibition of Cholesterol 7α-Hydroxylase Gene Transcription in Human Hepatocytes
      Shuxin Han and John Y. L. Chiang
      Drug Metabolism and Disposition March 2009, 37 (3) 469-478; DOI: https://doi.org/10.1124/dmd.108.025155
  8. Cho, Robert

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931

D

  1. Dansette, Patrick M.

    1. You have access
      Dehydrogenation of the Indoline-Containing Drug 4-Chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (Indapamide) by CYP3A4: Correlation with in Silico Predictions
      Hao Sun, Chad Moore, Patrick M. Dansette, Santosh Kumar, James R. Halpert and Garold S. Yost
      Drug Metabolism and Disposition March 2009, 37 (3) 672-684; DOI: https://doi.org/10.1124/dmd.108.022707
  2. Dees, E. Claire

    1. You have access
      Identification of a Cranberry Juice Product that Inhibits Enteric CYP3A-Mediated First-Pass Metabolism in Humans
      Ngoc Ngo, Zhixia Yan, Tyler N. Graf, Daniel R. Carrizosa, Angela D. M. Kashuba, E. Claire Dees, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition March 2009, 37 (3) 514-522; DOI: https://doi.org/10.1124/dmd.108.024968
  3. Ding, Xinxin

    1. You have access
      An Intestinal Epithelium-Specific Cytochrome P450 (P450) Reductase-Knockout Mouse Model: Direct Evidence for a Role of Intestinal P450s in First-Pass Clearance of Oral Nifedipine
      Qing-Yu Zhang, Cheng Fang, Jin Zhang, Deborah Dunbar, Laurence Kaminsky and Xinxin Ding
      Drug Metabolism and Disposition March 2009, 37 (3) 651-657; DOI: https://doi.org/10.1124/dmd.108.025429
  4. Dunbar, Deborah

    1. You have access
      An Intestinal Epithelium-Specific Cytochrome P450 (P450) Reductase-Knockout Mouse Model: Direct Evidence for a Role of Intestinal P450s in First-Pass Clearance of Oral Nifedipine
      Qing-Yu Zhang, Cheng Fang, Jin Zhang, Deborah Dunbar, Laurence Kaminsky and Xinxin Ding
      Drug Metabolism and Disposition March 2009, 37 (3) 651-657; DOI: https://doi.org/10.1124/dmd.108.025429

E

  1. Einolf, Heidi

    1. You have access
      Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Yannick Batard, Lai Wang, Heidi Einolf, Helen Gu, James B. Mangold, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 536-544; DOI: https://doi.org/10.1124/dmd.108.023010
  2. Elmquist, William F.

    1. You have access
      Substrate-Dependent Breast Cancer Resistance Protein (Bcrp1/Abcg2)-Mediated Interactions: Consideration of Multiple Binding Sites in in Vitro Assay Design
      Nagdeep Giri, Sagar Agarwal, Naveed Shaik, Guoyu Pan, Ying Chen and William F. Elmquist
      Drug Metabolism and Disposition March 2009, 37 (3) 560-570; DOI: https://doi.org/10.1124/dmd.108.022046
  3. Ethell, Brian T.

    1. You have access
      Evaluation of Escherichia coli Membrane Preparations of Canine CYP1A1, 2B11, 2C21, 2C41, 2D15, 3A12, and 3A26 with Coexpressed Canine Cytochrome P450 Reductase
      Charles W. Locuson, Brian T. Ethell, Michael Voice, David Lee and Kenneth L. Feenstra
      Drug Metabolism and Disposition March 2009, 37 (3) 457-461; DOI: https://doi.org/10.1124/dmd.108.025312
  4. Evanchik, Marc J.

    1. You have access
      Metabolism of (+)-1,4-Dihydro-7-(trans-3-methoxy-4-methylamino-1-pyrrolidinyl)-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic Acid (Voreloxin; Formerly SNS-595), a Novel Replication-Dependent DNA-Damaging Agent
      Marc J. Evanchik, Darin Allen, Josh C. Yoburn, Jeffrey A. Silverman and Ute Hoch
      Drug Metabolism and Disposition March 2009, 37 (3) 594-601; DOI: https://doi.org/10.1124/dmd.108.023432

F

  1. Fang, Cheng

    1. You have access
      An Intestinal Epithelium-Specific Cytochrome P450 (P450) Reductase-Knockout Mouse Model: Direct Evidence for a Role of Intestinal P450s in First-Pass Clearance of Oral Nifedipine
      Qing-Yu Zhang, Cheng Fang, Jin Zhang, Deborah Dunbar, Laurence Kaminsky and Xinxin Ding
      Drug Metabolism and Disposition March 2009, 37 (3) 651-657; DOI: https://doi.org/10.1124/dmd.108.025429
  2. Fardel, Olivier

    1. You have access
      Regulation of Drug Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokines Tumor Necrosis Factor-α or Interleukin-6
      Marc Le Vee, Valérie Lecureur, Bruno Stieger and Olivier Fardel
      Drug Metabolism and Disposition March 2009, 37 (3) 685-693; DOI: https://doi.org/10.1124/dmd.108.023630
  3. Farhadi, Ashkan

    1. You have access
      SIMDOT-AbMe: Microphysiologically Based Simulation Tool for Quantitative Prediction of Systemic and Local Bioavailability of Targeted Oral Delivery Formulations
      Nahor Haddish-Berhane, Ashkan Farhadi, Chell Nyquist, Kamyar Haghighi and Ali Keshavarzian
      Drug Metabolism and Disposition March 2009, 37 (3) 608-618; DOI: https://doi.org/10.1124/dmd.108.021949
  4. Farid, Nagy A.

    1. You have access
      Mechanism-Based Inhibition of Human Cytochrome P450 2B6 by Ticlopidine, Clopidogrel, and the Thiolactone Metabolite of Prasugrel
      Yumi Nishiya, Katsunobu Hagihara, Takashi Ito, Masami Tajima, Shin-ichi Miura, Atsushi Kurihara, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition March 2009, 37 (3) 589-593; DOI: https://doi.org/10.1124/dmd.108.022988
  5. Fawcett, J. Paul

    1. You have access
      Mechanism of CYP2C9 Inhibition by Flavones and Flavonols
      Dayong Si, Ying Wang, Yi-Han Zhou, Yingjie Guo, Juan Wang, Hui Zhou, Ze-Sheng Li and J. Paul Fawcett
      Drug Metabolism and Disposition March 2009, 37 (3) 629-634; DOI: https://doi.org/10.1124/dmd.108.023416
  6. Feenstra, Kenneth L.

    1. You have access
      Evaluation of Escherichia coli Membrane Preparations of Canine CYP1A1, 2B11, 2C21, 2C41, 2D15, 3A12, and 3A26 with Coexpressed Canine Cytochrome P450 Reductase
      Charles W. Locuson, Brian T. Ethell, Michael Voice, David Lee and Kenneth L. Feenstra
      Drug Metabolism and Disposition March 2009, 37 (3) 457-461; DOI: https://doi.org/10.1124/dmd.108.025312
  7. Filipeck, Ron

    1. You have access
      Disposition of Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Rats and Dogs
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Dennis Flood, Roger Kramp, Ron Filipeck, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 545-554; DOI: https://doi.org/10.1124/dmd.108.023002
  8. Fischer, Volker

    1. You have access
      Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Yannick Batard, Lai Wang, Heidi Einolf, Helen Gu, James B. Mangold, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 536-544; DOI: https://doi.org/10.1124/dmd.108.023010
    2. You have access
      Disposition of Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Rats and Dogs
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Dennis Flood, Roger Kramp, Ron Filipeck, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 545-554; DOI: https://doi.org/10.1124/dmd.108.023002
  9. Flood, Dennis

    1. You have access
      Disposition of Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Rats and Dogs
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Dennis Flood, Roger Kramp, Ron Filipeck, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 545-554; DOI: https://doi.org/10.1124/dmd.108.023002
  10. Floren, Leslie C.

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931

G

  1. Giri, Nagdeep

    1. You have access
      Substrate-Dependent Breast Cancer Resistance Protein (Bcrp1/Abcg2)-Mediated Interactions: Consideration of Multiple Binding Sites in in Vitro Assay Design
      Nagdeep Giri, Sagar Agarwal, Naveed Shaik, Guoyu Pan, Ying Chen and William F. Elmquist
      Drug Metabolism and Disposition March 2009, 37 (3) 560-570; DOI: https://doi.org/10.1124/dmd.108.022046
  2. Graf, Tyler N.

    1. You have access
      Identification of a Cranberry Juice Product that Inhibits Enteric CYP3A-Mediated First-Pass Metabolism in Humans
      Ngoc Ngo, Zhixia Yan, Tyler N. Graf, Daniel R. Carrizosa, Angela D. M. Kashuba, E. Claire Dees, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition March 2009, 37 (3) 514-522; DOI: https://doi.org/10.1124/dmd.108.024968
  3. Grönberg, Gunnar

    1. You have access
      Novel Metabolites of Amodiaquine Formed by CYP1A1 and CYP1B1: Structure Elucidation Using Electrochemistry, Mass Spectrometry, and NMR
      Tove Johansson, Ulrik Jurva, Gunnar Grönberg, Lars Weidolf and Collen Masimirembwa
      Drug Metabolism and Disposition March 2009, 37 (3) 571-579; DOI: https://doi.org/10.1124/dmd.108.025171
  4. Gu, Helen

    1. You have access
      Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Yannick Batard, Lai Wang, Heidi Einolf, Helen Gu, James B. Mangold, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 536-544; DOI: https://doi.org/10.1124/dmd.108.023010
  5. Guo, Yingjie

    1. You have access
      Mechanism of CYP2C9 Inhibition by Flavones and Flavonols
      Dayong Si, Ying Wang, Yi-Han Zhou, Yingjie Guo, Juan Wang, Hui Zhou, Ze-Sheng Li and J. Paul Fawcett
      Drug Metabolism and Disposition March 2009, 37 (3) 629-634; DOI: https://doi.org/10.1124/dmd.108.023416

H

  1. Haddish-Berhane, Nahor

    1. You have access
      SIMDOT-AbMe: Microphysiologically Based Simulation Tool for Quantitative Prediction of Systemic and Local Bioavailability of Targeted Oral Delivery Formulations
      Nahor Haddish-Berhane, Ashkan Farhadi, Chell Nyquist, Kamyar Haghighi and Ali Keshavarzian
      Drug Metabolism and Disposition March 2009, 37 (3) 608-618; DOI: https://doi.org/10.1124/dmd.108.021949
  2. Haghighi, Kamyar

    1. You have access
      SIMDOT-AbMe: Microphysiologically Based Simulation Tool for Quantitative Prediction of Systemic and Local Bioavailability of Targeted Oral Delivery Formulations
      Nahor Haddish-Berhane, Ashkan Farhadi, Chell Nyquist, Kamyar Haghighi and Ali Keshavarzian
      Drug Metabolism and Disposition March 2009, 37 (3) 608-618; DOI: https://doi.org/10.1124/dmd.108.021949
  3. Hagihara, Katsunobu

    1. You have access
      Mechanism-Based Inhibition of Human Cytochrome P450 2B6 by Ticlopidine, Clopidogrel, and the Thiolactone Metabolite of Prasugrel
      Yumi Nishiya, Katsunobu Hagihara, Takashi Ito, Masami Tajima, Shin-ichi Miura, Atsushi Kurihara, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition March 2009, 37 (3) 589-593; DOI: https://doi.org/10.1124/dmd.108.022988
  4. Halpert, James R.

    1. You have access
      Decreased Susceptibility of the Cytochrome P450 2B6 Variant K262R to Inhibition by Several Clinically Important Drugs
      Jyothi C. Talakad, Santosh Kumar and James R. Halpert
      Drug Metabolism and Disposition March 2009, 37 (3) 644-650; DOI: https://doi.org/10.1124/dmd.108.023655
    2. You have access
      Dehydrogenation of the Indoline-Containing Drug 4-Chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (Indapamide) by CYP3A4: Correlation with in Silico Predictions
      Hao Sun, Chad Moore, Patrick M. Dansette, Santosh Kumar, James R. Halpert and Garold S. Yost
      Drug Metabolism and Disposition March 2009, 37 (3) 672-684; DOI: https://doi.org/10.1124/dmd.108.022707
  5. Hammarlund-Udenaes, Margareta

    1. You have access
      Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
      Stina Syvänen, Örjan Lindhe, Mikael Palner, Birgitte R. Kornum, Obaidur Rahman, Bengt Långström, Gitte M. Knudsen and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition March 2009, 37 (3) 635-643; DOI: https://doi.org/10.1124/dmd.108.024745
  6. Han, Shuxin

    1. You have access
      Mechanism of Vitamin D Receptor Inhibition of Cholesterol 7α-Hydroxylase Gene Transcription in Human Hepatocytes
      Shuxin Han and John Y. L. Chiang
      Drug Metabolism and Disposition March 2009, 37 (3) 469-478; DOI: https://doi.org/10.1124/dmd.108.025155
  7. Harada, Akihiro

    1. You have access
      Investigation of the Role of Oligopeptide Transporter PEPT1 and Sodium/Glucose Cotransporter SGLT1 in Intestinal Absorption of Their Substrates Using Small GTP-Binding Protein Rab8-Null Mice
      Yukio Kato, Tomoko Sugiura, Yasuhito Nakadera, Mikihiro Sugiura, Yoshiyuki Kubo, Takashi Sato, Akihiro Harada and Akira Tsuji
      Drug Metabolism and Disposition March 2009, 37 (3) 602-607; DOI: https://doi.org/10.1124/dmd.108.023689
  8. He, Handan

    1. You have access
      Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Yannick Batard, Lai Wang, Heidi Einolf, Helen Gu, James B. Mangold, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 536-544; DOI: https://doi.org/10.1124/dmd.108.023010
    2. You have access
      Disposition of Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Rats and Dogs
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Dennis Flood, Roger Kramp, Ron Filipeck, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 545-554; DOI: https://doi.org/10.1124/dmd.108.023002
  9. Hoch, Ute

    1. You have access
      Metabolism of (+)-1,4-Dihydro-7-(trans-3-methoxy-4-methylamino-1-pyrrolidinyl)-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic Acid (Voreloxin; Formerly SNS-595), a Novel Replication-Dependent DNA-Damaging Agent
      Marc J. Evanchik, Darin Allen, Josh C. Yoburn, Jeffrey A. Silverman and Ute Hoch
      Drug Metabolism and Disposition March 2009, 37 (3) 594-601; DOI: https://doi.org/10.1124/dmd.108.023432
  10. Horita, Shigeru

    1. You have access
      The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
      Soichiro Matsushima, Kazuya Maeda, Katsuhisa Inoue, Kin-ya Ohta, Hiroaki Yuasa, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2009, 37 (3) 555-559; DOI: https://doi.org/10.1124/dmd.108.023911
  11. Howard, Dan

    1. You have access
      Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Yannick Batard, Lai Wang, Heidi Einolf, Helen Gu, James B. Mangold, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 536-544; DOI: https://doi.org/10.1124/dmd.108.023010
    2. You have access
      Disposition of Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Rats and Dogs
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Dennis Flood, Roger Kramp, Ron Filipeck, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 545-554; DOI: https://doi.org/10.1124/dmd.108.023002

I

  1. Ikeda, Toshihiko

    1. You have access
      Mechanism-Based Inhibition of Human Cytochrome P450 2B6 by Ticlopidine, Clopidogrel, and the Thiolactone Metabolite of Prasugrel
      Yumi Nishiya, Katsunobu Hagihara, Takashi Ito, Masami Tajima, Shin-ichi Miura, Atsushi Kurihara, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition March 2009, 37 (3) 589-593; DOI: https://doi.org/10.1124/dmd.108.022988
  2. Inoue, Katsuhisa

    1. You have access
      The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
      Soichiro Matsushima, Kazuya Maeda, Katsuhisa Inoue, Kin-ya Ohta, Hiroaki Yuasa, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2009, 37 (3) 555-559; DOI: https://doi.org/10.1124/dmd.108.023911
  3. Ito, Takashi

    1. You have access
      Mechanism-Based Inhibition of Human Cytochrome P450 2B6 by Ticlopidine, Clopidogrel, and the Thiolactone Metabolite of Prasugrel
      Yumi Nishiya, Katsunobu Hagihara, Takashi Ito, Masami Tajima, Shin-ichi Miura, Atsushi Kurihara, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition March 2009, 37 (3) 589-593; DOI: https://doi.org/10.1124/dmd.108.022988
  4. Iwai, Megumi

    1. You have access
      Carrier-Mediated Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small-Molecule Survivin Suppressant, into Human Solid Tumor and Lymphoma Cells
      Tsuyoshi Minematsu, Megumi Iwai, Kenji Sugimoto, Nobuaki Shirai, Takahito Nakahara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition March 2009, 37 (3) 619-628; DOI: https://doi.org/10.1124/dmd.108.025254

J

  1. Jasko, Maxim V.

    1. You have access
      5′-Aminocarbonyl Phosphonates as New Zidovudine Depot Forms: Antiviral Properties, Intracellular Transformations, and Pharmacokinetic Parameters
      Anastasia L. Khandazhinskaya, Dmitry V. Yanvarev, Maxim V. Jasko, Alexander V. Shipitsin, Vsevolod A. Khalizev, Stanislav I. Shram, Yuriy S. Skoblov, Elena A. Shirokova and Marina K. Kukhanova
      Drug Metabolism and Disposition March 2009, 37 (3) 494-501; DOI: https://doi.org/10.1124/dmd.108.022269
  2. Jiang, Xi-Ling

    1. You have access
      Pinoline May be Used as a Probe for CYP2D6 Activity
      Xi-Ling Jiang, Hong-Wu Shen and Ai-Ming Yu
      Drug Metabolism and Disposition March 2009, 37 (3) 443-446; DOI: https://doi.org/10.1124/dmd.108.025056
  3. Johansson, Tove

    1. You have access
      Novel Metabolites of Amodiaquine Formed by CYP1A1 and CYP1B1: Structure Elucidation Using Electrochemistry, Mass Spectrometry, and NMR
      Tove Johansson, Ulrik Jurva, Gunnar Grönberg, Lars Weidolf and Collen Masimirembwa
      Drug Metabolism and Disposition March 2009, 37 (3) 571-579; DOI: https://doi.org/10.1124/dmd.108.025171
  4. Johnson, Michael G.

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  5. Jørgensen, Flemming Steen

    1. You have access
      Classification of Cytochrome P450 1A2 Inhibitors and Noninhibitors by Machine Learning Techniques
      Poongavanam Vasanthanathan, Olivier Taboureau, Chris Oostenbrink, Nico P. E. Vermeulen, Lars Olsen and Flemming Steen Jørgensen
      Drug Metabolism and Disposition March 2009, 37 (3) 658-664; DOI: https://doi.org/10.1124/dmd.108.023507
  6. Jurva, Ulrik

    1. You have access
      Novel Metabolites of Amodiaquine Formed by CYP1A1 and CYP1B1: Structure Elucidation Using Electrochemistry, Mass Spectrometry, and NMR
      Tove Johansson, Ulrik Jurva, Gunnar Grönberg, Lars Weidolf and Collen Masimirembwa
      Drug Metabolism and Disposition March 2009, 37 (3) 571-579; DOI: https://doi.org/10.1124/dmd.108.025171

K

  1. Kalvass, J. Cory

    1. You have access
      Fexofenadine Brain Exposure and the Influence of Blood-Brain Barrier P-Glycoprotein After Fexofenadine and Terfenadine Administration
      Rong Zhao, J. Cory Kalvass, Souzan B. Yanni, Arlene S. Bridges and Gary M. Pollack
      Drug Metabolism and Disposition March 2009, 37 (3) 529-535; DOI: https://doi.org/10.1124/dmd.107.019893
  2. Kamataki, Tetsuya

    1. You have access
      Sex-Related Differences in the Expression of mfGSTA2, a Novel GST Identified in Cynomolgus Monkey (Macaca fascicularis)
      Yasuhiro Uno, Tsukasa Ohuchi, Shotaro Uehara, Go Kito, Tetsuya Kamataki and Ryoichi Nagata
      Drug Metabolism and Disposition March 2009, 37 (3) 453-456; DOI: https://doi.org/10.1124/dmd.108.023747
  3. Kamimura, Hidetaka

    1. You have access
      Carrier-Mediated Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small-Molecule Survivin Suppressant, into Human Solid Tumor and Lymphoma Cells
      Tsuyoshi Minematsu, Megumi Iwai, Kenji Sugimoto, Nobuaki Shirai, Takahito Nakahara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition March 2009, 37 (3) 619-628; DOI: https://doi.org/10.1124/dmd.108.025254
  4. Kaminsky, Laurence

    1. You have access
      An Intestinal Epithelium-Specific Cytochrome P450 (P450) Reductase-Knockout Mouse Model: Direct Evidence for a Role of Intestinal P450s in First-Pass Clearance of Oral Nifedipine
      Qing-Yu Zhang, Cheng Fang, Jin Zhang, Deborah Dunbar, Laurence Kaminsky and Xinxin Ding
      Drug Metabolism and Disposition March 2009, 37 (3) 651-657; DOI: https://doi.org/10.1124/dmd.108.025429
  5. Kashuba, Angela D. M.

    1. You have access
      Identification of a Cranberry Juice Product that Inhibits Enteric CYP3A-Mediated First-Pass Metabolism in Humans
      Ngoc Ngo, Zhixia Yan, Tyler N. Graf, Daniel R. Carrizosa, Angela D. M. Kashuba, E. Claire Dees, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition March 2009, 37 (3) 514-522; DOI: https://doi.org/10.1124/dmd.108.024968
  6. Kato, Yukio

    1. You have access
      Investigation of the Role of Oligopeptide Transporter PEPT1 and Sodium/Glucose Cotransporter SGLT1 in Intestinal Absorption of Their Substrates Using Small GTP-Binding Protein Rab8-Null Mice
      Yukio Kato, Tomoko Sugiura, Yasuhito Nakadera, Mikihiro Sugiura, Yoshiyuki Kubo, Takashi Sato, Akihiro Harada and Akira Tsuji
      Drug Metabolism and Disposition March 2009, 37 (3) 602-607; DOI: https://doi.org/10.1124/dmd.108.023689
  7. Kawai, Masahiko

    1. You have access
      Developmental Expression and Endocrine Regulation of CYP1B1 in Rat Testis
      Grace S. Leung, Masahiko Kawai, Jenny K. Tai, Jie Chen, Stelvio M. Bandiera and Thomas K. H. Chang
      Drug Metabolism and Disposition March 2009, 37 (3) 523-528; DOI: https://doi.org/10.1124/dmd.108.025635
  8. Kersey, Kathryn

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  9. Keshavarzian, Ali

    1. You have access
      SIMDOT-AbMe: Microphysiologically Based Simulation Tool for Quantitative Prediction of Systemic and Local Bioavailability of Targeted Oral Delivery Formulations
      Nahor Haddish-Berhane, Ashkan Farhadi, Chell Nyquist, Kamyar Haghighi and Ali Keshavarzian
      Drug Metabolism and Disposition March 2009, 37 (3) 608-618; DOI: https://doi.org/10.1124/dmd.108.021949
  10. Khalizev, Vsevolod A.

    1. You have access
      5′-Aminocarbonyl Phosphonates as New Zidovudine Depot Forms: Antiviral Properties, Intracellular Transformations, and Pharmacokinetic Parameters
      Anastasia L. Khandazhinskaya, Dmitry V. Yanvarev, Maxim V. Jasko, Alexander V. Shipitsin, Vsevolod A. Khalizev, Stanislav I. Shram, Yuriy S. Skoblov, Elena A. Shirokova and Marina K. Kukhanova
      Drug Metabolism and Disposition March 2009, 37 (3) 494-501; DOI: https://doi.org/10.1124/dmd.108.022269
  11. Khandazhinskaya, Anastasia L.

    1. You have access
      5′-Aminocarbonyl Phosphonates as New Zidovudine Depot Forms: Antiviral Properties, Intracellular Transformations, and Pharmacokinetic Parameters
      Anastasia L. Khandazhinskaya, Dmitry V. Yanvarev, Maxim V. Jasko, Alexander V. Shipitsin, Vsevolod A. Khalizev, Stanislav I. Shram, Yuriy S. Skoblov, Elena A. Shirokova and Marina K. Kukhanova
      Drug Metabolism and Disposition March 2009, 37 (3) 494-501; DOI: https://doi.org/10.1124/dmd.108.022269
  12. Kito, Go

    1. You have access
      Sex-Related Differences in the Expression of mfGSTA2, a Novel GST Identified in Cynomolgus Monkey (Macaca fascicularis)
      Yasuhiro Uno, Tsukasa Ohuchi, Shotaro Uehara, Go Kito, Tetsuya Kamataki and Ryoichi Nagata
      Drug Metabolism and Disposition March 2009, 37 (3) 453-456; DOI: https://doi.org/10.1124/dmd.108.023747
  13. Knudsen, Gitte M.

    1. You have access
      Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
      Stina Syvänen, Örjan Lindhe, Mikael Palner, Birgitte R. Kornum, Obaidur Rahman, Bengt Långström, Gitte M. Knudsen and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition March 2009, 37 (3) 635-643; DOI: https://doi.org/10.1124/dmd.108.024745
  14. Kondo, Tsunenori

    1. You have access
      The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
      Soichiro Matsushima, Kazuya Maeda, Katsuhisa Inoue, Kin-ya Ohta, Hiroaki Yuasa, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2009, 37 (3) 555-559; DOI: https://doi.org/10.1124/dmd.108.023911
  15. Kornum, Birgitte R.

    1. You have access
      Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
      Stina Syvänen, Örjan Lindhe, Mikael Palner, Birgitte R. Kornum, Obaidur Rahman, Bengt Långström, Gitte M. Knudsen and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition March 2009, 37 (3) 635-643; DOI: https://doi.org/10.1124/dmd.108.024745
  16. Kramp, Roger

    1. You have access
      Disposition of Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Rats and Dogs
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Dennis Flood, Roger Kramp, Ron Filipeck, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 545-554; DOI: https://doi.org/10.1124/dmd.108.023002
  17. Kubo, Yoshiyuki

    1. You have access
      Investigation of the Role of Oligopeptide Transporter PEPT1 and Sodium/Glucose Cotransporter SGLT1 in Intestinal Absorption of Their Substrates Using Small GTP-Binding Protein Rab8-Null Mice
      Yukio Kato, Tomoko Sugiura, Yasuhito Nakadera, Mikihiro Sugiura, Yoshiyuki Kubo, Takashi Sato, Akihiro Harada and Akira Tsuji
      Drug Metabolism and Disposition March 2009, 37 (3) 602-607; DOI: https://doi.org/10.1124/dmd.108.023689
  18. Kukhanova, Marina K.

    1. You have access
      5′-Aminocarbonyl Phosphonates as New Zidovudine Depot Forms: Antiviral Properties, Intracellular Transformations, and Pharmacokinetic Parameters
      Anastasia L. Khandazhinskaya, Dmitry V. Yanvarev, Maxim V. Jasko, Alexander V. Shipitsin, Vsevolod A. Khalizev, Stanislav I. Shram, Yuriy S. Skoblov, Elena A. Shirokova and Marina K. Kukhanova
      Drug Metabolism and Disposition March 2009, 37 (3) 494-501; DOI: https://doi.org/10.1124/dmd.108.022269
  19. Kumar, Santosh

    1. You have access
      Decreased Susceptibility of the Cytochrome P450 2B6 Variant K262R to Inhibition by Several Clinically Important Drugs
      Jyothi C. Talakad, Santosh Kumar and James R. Halpert
      Drug Metabolism and Disposition March 2009, 37 (3) 644-650; DOI: https://doi.org/10.1124/dmd.108.023655
    2. You have access
      Dehydrogenation of the Indoline-Containing Drug 4-Chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (Indapamide) by CYP3A4: Correlation with in Silico Predictions
      Hao Sun, Chad Moore, Patrick M. Dansette, Santosh Kumar, James R. Halpert and Garold S. Yost
      Drug Metabolism and Disposition March 2009, 37 (3) 672-684; DOI: https://doi.org/10.1124/dmd.108.022707
  20. Kurihara, Atsushi

    1. You have access
      Mechanism-Based Inhibition of Human Cytochrome P450 2B6 by Ticlopidine, Clopidogrel, and the Thiolactone Metabolite of Prasugrel
      Yumi Nishiya, Katsunobu Hagihara, Takashi Ito, Masami Tajima, Shin-ichi Miura, Atsushi Kurihara, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition March 2009, 37 (3) 589-593; DOI: https://doi.org/10.1124/dmd.108.022988
  21. Kusuhara, Hiroyuki

    1. You have access
      The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
      Soichiro Matsushima, Kazuya Maeda, Katsuhisa Inoue, Kin-ya Ohta, Hiroaki Yuasa, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2009, 37 (3) 555-559; DOI: https://doi.org/10.1124/dmd.108.023911

L

  1. Lalk, Michael

    1. You have access
      Investigation of the in Vitro Metabolism of the Analgesic Flupirtine
      Karen Methling, Przyemslaw Reszka, Michael Lalk, Oldrich Vrana, Eberhard Scheuch, Werner Siegmund, Bernd Terhaag and Patrick J. Bednarski
      Drug Metabolism and Disposition March 2009, 37 (3) 479-493; DOI: https://doi.org/10.1124/dmd.108.024364
  2. Långström, Bengt

    1. You have access
      Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
      Stina Syvänen, Örjan Lindhe, Mikael Palner, Birgitte R. Kornum, Obaidur Rahman, Bengt Långström, Gitte M. Knudsen and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition March 2009, 37 (3) 635-643; DOI: https://doi.org/10.1124/dmd.108.024745
  3. Lecureur, Valérie

    1. You have access
      Regulation of Drug Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokines Tumor Necrosis Factor-α or Interleukin-6
      Marc Le Vee, Valérie Lecureur, Bruno Stieger and Olivier Fardel
      Drug Metabolism and Disposition March 2009, 37 (3) 685-693; DOI: https://doi.org/10.1124/dmd.108.023630
  4. Lee, David

    1. You have access
      Evaluation of Escherichia coli Membrane Preparations of Canine CYP1A1, 2B11, 2C21, 2C41, 2D15, 3A12, and 3A26 with Coexpressed Canine Cytochrome P450 Reductase
      Charles W. Locuson, Brian T. Ethell, Michael Voice, David Lee and Kenneth L. Feenstra
      Drug Metabolism and Disposition March 2009, 37 (3) 457-461; DOI: https://doi.org/10.1124/dmd.108.025312
  5. Leung, Grace S.

    1. You have access
      Developmental Expression and Endocrine Regulation of CYP1B1 in Rat Testis
      Grace S. Leung, Masahiko Kawai, Jenny K. Tai, Jie Chen, Stelvio M. Bandiera and Thomas K. H. Chang
      Drug Metabolism and Disposition March 2009, 37 (3) 523-528; DOI: https://doi.org/10.1124/dmd.108.025635
  6. Li, Ze-Sheng

    1. You have access
      Mechanism of CYP2C9 Inhibition by Flavones and Flavonols
      Dayong Si, Ying Wang, Yi-Han Zhou, Yingjie Guo, Juan Wang, Hui Zhou, Ze-Sheng Li and J. Paul Fawcett
      Drug Metabolism and Disposition March 2009, 37 (3) 629-634; DOI: https://doi.org/10.1124/dmd.108.023416
  7. Lindhe, Örjan

    1. You have access
      Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
      Stina Syvänen, Örjan Lindhe, Mikael Palner, Birgitte R. Kornum, Obaidur Rahman, Bengt Långström, Gitte M. Knudsen and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition March 2009, 37 (3) 635-643; DOI: https://doi.org/10.1124/dmd.108.024745
  8. Locuson, Charles W.

    1. You have access
      Evaluation of Escherichia coli Membrane Preparations of Canine CYP1A1, 2B11, 2C21, 2C41, 2D15, 3A12, and 3A26 with Coexpressed Canine Cytochrome P450 Reductase
      Charles W. Locuson, Brian T. Ethell, Michael Voice, David Lee and Kenneth L. Feenstra
      Drug Metabolism and Disposition March 2009, 37 (3) 457-461; DOI: https://doi.org/10.1124/dmd.108.025312

M

  1. Ma, Ji

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  2. Maeda, Kazuya

    1. You have access
      The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
      Soichiro Matsushima, Kazuya Maeda, Katsuhisa Inoue, Kin-ya Ohta, Hiroaki Yuasa, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2009, 37 (3) 555-559; DOI: https://doi.org/10.1124/dmd.108.023911
  3. Mangold, James B.

    1. You have access
      Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Yannick Batard, Lai Wang, Heidi Einolf, Helen Gu, James B. Mangold, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 536-544; DOI: https://doi.org/10.1124/dmd.108.023010
  4. Marcus, Andrew P.

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  5. Masimirembwa, Collen

    1. You have access
      Novel Metabolites of Amodiaquine Formed by CYP1A1 and CYP1B1: Structure Elucidation Using Electrochemistry, Mass Spectrometry, and NMR
      Tove Johansson, Ulrik Jurva, Gunnar Grönberg, Lars Weidolf and Collen Masimirembwa
      Drug Metabolism and Disposition March 2009, 37 (3) 571-579; DOI: https://doi.org/10.1124/dmd.108.025171
  6. Matsushima, Soichiro

    1. You have access
      The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
      Soichiro Matsushima, Kazuya Maeda, Katsuhisa Inoue, Kin-ya Ohta, Hiroaki Yuasa, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2009, 37 (3) 555-559; DOI: https://doi.org/10.1124/dmd.108.023911
  7. Medina, Julio C.

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  8. Methling, Karen

    1. You have access
      Investigation of the in Vitro Metabolism of the Analgesic Flupirtine
      Karen Methling, Przyemslaw Reszka, Michael Lalk, Oldrich Vrana, Eberhard Scheuch, Werner Siegmund, Bernd Terhaag and Patrick J. Bednarski
      Drug Metabolism and Disposition March 2009, 37 (3) 479-493; DOI: https://doi.org/10.1124/dmd.108.024364
  9. Minematsu, Tsuyoshi

    1. You have access
      Carrier-Mediated Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small-Molecule Survivin Suppressant, into Human Solid Tumor and Lymphoma Cells
      Tsuyoshi Minematsu, Megumi Iwai, Kenji Sugimoto, Nobuaki Shirai, Takahito Nakahara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition March 2009, 37 (3) 619-628; DOI: https://doi.org/10.1124/dmd.108.025254
  10. Miura, Shin-ichi

    1. You have access
      Mechanism-Based Inhibition of Human Cytochrome P450 2B6 by Ticlopidine, Clopidogrel, and the Thiolactone Metabolite of Prasugrel
      Yumi Nishiya, Katsunobu Hagihara, Takashi Ito, Masami Tajima, Shin-ichi Miura, Atsushi Kurihara, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition March 2009, 37 (3) 589-593; DOI: https://doi.org/10.1124/dmd.108.022988
  11. Moore, Chad

    1. You have access
      Dehydrogenation of the Indoline-Containing Drug 4-Chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (Indapamide) by CYP3A4: Correlation with in Silico Predictions
      Hao Sun, Chad Moore, Patrick M. Dansette, Santosh Kumar, James R. Halpert and Garold S. Yost
      Drug Metabolism and Disposition March 2009, 37 (3) 672-684; DOI: https://doi.org/10.1124/dmd.108.022707
  12. Morgan, Edward T.

    1. You have access
      Hepatic Flavin-Containing Monooxygenase Gene Regulation in Different Mouse Inflammation Models
      Jun Zhang, Madhusudana R. Chaluvadi, Rob Reddy, Meike S. Motika, Terrilyn A. Richardson, John R. Cashman and Edward T. Morgan
      Drug Metabolism and Disposition March 2009, 37 (3) 462-468; DOI: https://doi.org/10.1124/dmd.108.025338
  13. Motika, Meike S.

    1. You have access
      Hepatic Flavin-Containing Monooxygenase Gene Regulation in Different Mouse Inflammation Models
      Jun Zhang, Madhusudana R. Chaluvadi, Rob Reddy, Meike S. Motika, Terrilyn A. Richardson, John R. Cashman and Edward T. Morgan
      Drug Metabolism and Disposition March 2009, 37 (3) 462-468; DOI: https://doi.org/10.1124/dmd.108.025338
  14. Murphy, Sharon E.

    1. You have access
      Effect of CYP2A13 Active Site Mutation N297A on Metabolism of Coumarin and Tobacco-Specific Nitrosamines
      Kari E. Schlicht, Jeannette Zinggeler Berg and Sharon E. Murphy
      Drug Metabolism and Disposition March 2009, 37 (3) 665-671; DOI: https://doi.org/10.1124/dmd.108.025072

N

  1. Nagata, Ryoichi

    1. You have access
      Sex-Related Differences in the Expression of mfGSTA2, a Novel GST Identified in Cynomolgus Monkey (Macaca fascicularis)
      Yasuhiro Uno, Tsukasa Ohuchi, Shotaro Uehara, Go Kito, Tetsuya Kamataki and Ryoichi Nagata
      Drug Metabolism and Disposition March 2009, 37 (3) 453-456; DOI: https://doi.org/10.1124/dmd.108.023747
  2. Nakadera, Yasuhito

    1. You have access
      Investigation of the Role of Oligopeptide Transporter PEPT1 and Sodium/Glucose Cotransporter SGLT1 in Intestinal Absorption of Their Substrates Using Small GTP-Binding Protein Rab8-Null Mice
      Yukio Kato, Tomoko Sugiura, Yasuhito Nakadera, Mikihiro Sugiura, Yoshiyuki Kubo, Takashi Sato, Akihiro Harada and Akira Tsuji
      Drug Metabolism and Disposition March 2009, 37 (3) 602-607; DOI: https://doi.org/10.1124/dmd.108.023689
  3. Nakahara, Takahito

    1. You have access
      Carrier-Mediated Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small-Molecule Survivin Suppressant, into Human Solid Tumor and Lymphoma Cells
      Tsuyoshi Minematsu, Megumi Iwai, Kenji Sugimoto, Nobuaki Shirai, Takahito Nakahara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition March 2009, 37 (3) 619-628; DOI: https://doi.org/10.1124/dmd.108.025254
  4. Nakayama, Hideki

    1. You have access
      The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
      Soichiro Matsushima, Kazuya Maeda, Katsuhisa Inoue, Kin-ya Ohta, Hiroaki Yuasa, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2009, 37 (3) 555-559; DOI: https://doi.org/10.1124/dmd.108.023911
  5. Ngo, Ngoc

    1. You have access
      Identification of a Cranberry Juice Product that Inhibits Enteric CYP3A-Mediated First-Pass Metabolism in Humans
      Ngoc Ngo, Zhixia Yan, Tyler N. Graf, Daniel R. Carrizosa, Angela D. M. Kashuba, E. Claire Dees, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition March 2009, 37 (3) 514-522; DOI: https://doi.org/10.1124/dmd.108.024968
  6. Nishiya, Yumi

    1. You have access
      Mechanism-Based Inhibition of Human Cytochrome P450 2B6 by Ticlopidine, Clopidogrel, and the Thiolactone Metabolite of Prasugrel
      Yumi Nishiya, Katsunobu Hagihara, Takashi Ito, Masami Tajima, Shin-ichi Miura, Atsushi Kurihara, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition March 2009, 37 (3) 589-593; DOI: https://doi.org/10.1124/dmd.108.022988
  7. Nyquist, Chell

    1. You have access
      SIMDOT-AbMe: Microphysiologically Based Simulation Tool for Quantitative Prediction of Systemic and Local Bioavailability of Targeted Oral Delivery Formulations
      Nahor Haddish-Berhane, Ashkan Farhadi, Chell Nyquist, Kamyar Haghighi and Ali Keshavarzian
      Drug Metabolism and Disposition March 2009, 37 (3) 608-618; DOI: https://doi.org/10.1124/dmd.108.021949

O

  1. Oberlies, Nicholas H.

    1. You have access
      Identification of a Cranberry Juice Product that Inhibits Enteric CYP3A-Mediated First-Pass Metabolism in Humans
      Ngoc Ngo, Zhixia Yan, Tyler N. Graf, Daniel R. Carrizosa, Angela D. M. Kashuba, E. Claire Dees, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition March 2009, 37 (3) 514-522; DOI: https://doi.org/10.1124/dmd.108.024968
  2. Ohta, Kin-ya

    1. You have access
      The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
      Soichiro Matsushima, Kazuya Maeda, Katsuhisa Inoue, Kin-ya Ohta, Hiroaki Yuasa, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2009, 37 (3) 555-559; DOI: https://doi.org/10.1124/dmd.108.023911
  3. Ohuchi, Tsukasa

    1. You have access
      Sex-Related Differences in the Expression of mfGSTA2, a Novel GST Identified in Cynomolgus Monkey (Macaca fascicularis)
      Yasuhiro Uno, Tsukasa Ohuchi, Shotaro Uehara, Go Kito, Tetsuya Kamataki and Ryoichi Nagata
      Drug Metabolism and Disposition March 2009, 37 (3) 453-456; DOI: https://doi.org/10.1124/dmd.108.023747
  4. Olsen, Lars

    1. You have access
      Classification of Cytochrome P450 1A2 Inhibitors and Noninhibitors by Machine Learning Techniques
      Poongavanam Vasanthanathan, Olivier Taboureau, Chris Oostenbrink, Nico P. E. Vermeulen, Lars Olsen and Flemming Steen Jørgensen
      Drug Metabolism and Disposition March 2009, 37 (3) 658-664; DOI: https://doi.org/10.1124/dmd.108.023507
  5. Oostenbrink, Chris

    1. You have access
      Classification of Cytochrome P450 1A2 Inhibitors and Noninhibitors by Machine Learning Techniques
      Poongavanam Vasanthanathan, Olivier Taboureau, Chris Oostenbrink, Nico P. E. Vermeulen, Lars Olsen and Flemming Steen Jørgensen
      Drug Metabolism and Disposition March 2009, 37 (3) 658-664; DOI: https://doi.org/10.1124/dmd.108.023507

P

  1. Paine, Mary F.

    1. You have access
      Identification of a Cranberry Juice Product that Inhibits Enteric CYP3A-Mediated First-Pass Metabolism in Humans
      Ngoc Ngo, Zhixia Yan, Tyler N. Graf, Daniel R. Carrizosa, Angela D. M. Kashuba, E. Claire Dees, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition March 2009, 37 (3) 514-522; DOI: https://doi.org/10.1124/dmd.108.024968
  2. Palner, Mikael

    1. You have access
      Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
      Stina Syvänen, Örjan Lindhe, Mikael Palner, Birgitte R. Kornum, Obaidur Rahman, Bengt Långström, Gitte M. Knudsen and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition March 2009, 37 (3) 635-643; DOI: https://doi.org/10.1124/dmd.108.024745
  3. Pan, Guoyu

    1. You have access
      Substrate-Dependent Breast Cancer Resistance Protein (Bcrp1/Abcg2)-Mediated Interactions: Consideration of Multiple Binding Sites in in Vitro Assay Design
      Nagdeep Giri, Sagar Agarwal, Naveed Shaik, Guoyu Pan, Ying Chen and William F. Elmquist
      Drug Metabolism and Disposition March 2009, 37 (3) 560-570; DOI: https://doi.org/10.1124/dmd.108.022046
  4. Pearson, Paul G.

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  5. Pollack, Gary M.

    1. You have access
      Fexofenadine Brain Exposure and the Influence of Blood-Brain Barrier P-Glycoprotein After Fexofenadine and Terfenadine Administration
      Rong Zhao, J. Cory Kalvass, Souzan B. Yanni, Arlene S. Bridges and Gary M. Pollack
      Drug Metabolism and Disposition March 2009, 37 (3) 529-535; DOI: https://doi.org/10.1124/dmd.107.019893

R

  1. Rahman, Obaidur

    1. You have access
      Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
      Stina Syvänen, Örjan Lindhe, Mikael Palner, Birgitte R. Kornum, Obaidur Rahman, Bengt Långström, Gitte M. Knudsen and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition March 2009, 37 (3) 635-643; DOI: https://doi.org/10.1124/dmd.108.024745
  2. Reddy, Rob

    1. You have access
      Hepatic Flavin-Containing Monooxygenase Gene Regulation in Different Mouse Inflammation Models
      Jun Zhang, Madhusudana R. Chaluvadi, Rob Reddy, Meike S. Motika, Terrilyn A. Richardson, John R. Cashman and Edward T. Morgan
      Drug Metabolism and Disposition March 2009, 37 (3) 462-468; DOI: https://doi.org/10.1124/dmd.108.025338
  3. Reszka, Przyemslaw

    1. You have access
      Investigation of the in Vitro Metabolism of the Analgesic Flupirtine
      Karen Methling, Przyemslaw Reszka, Michael Lalk, Oldrich Vrana, Eberhard Scheuch, Werner Siegmund, Bernd Terhaag and Patrick J. Bednarski
      Drug Metabolism and Disposition March 2009, 37 (3) 479-493; DOI: https://doi.org/10.1124/dmd.108.024364
  4. Richardson, Terrilyn A.

    1. You have access
      Hepatic Flavin-Containing Monooxygenase Gene Regulation in Different Mouse Inflammation Models
      Jun Zhang, Madhusudana R. Chaluvadi, Rob Reddy, Meike S. Motika, Terrilyn A. Richardson, John R. Cashman and Edward T. Morgan
      Drug Metabolism and Disposition March 2009, 37 (3) 462-468; DOI: https://doi.org/10.1124/dmd.108.025338

S

  1. Sato, Takashi

    1. You have access
      Investigation of the Role of Oligopeptide Transporter PEPT1 and Sodium/Glucose Cotransporter SGLT1 in Intestinal Absorption of Their Substrates Using Small GTP-Binding Protein Rab8-Null Mice
      Yukio Kato, Tomoko Sugiura, Yasuhito Nakadera, Mikihiro Sugiura, Yoshiyuki Kubo, Takashi Sato, Akihiro Harada and Akira Tsuji
      Drug Metabolism and Disposition March 2009, 37 (3) 602-607; DOI: https://doi.org/10.1124/dmd.108.023689
  2. Scheuch, Eberhard

    1. You have access
      Investigation of the in Vitro Metabolism of the Analgesic Flupirtine
      Karen Methling, Przyemslaw Reszka, Michael Lalk, Oldrich Vrana, Eberhard Scheuch, Werner Siegmund, Bernd Terhaag and Patrick J. Bednarski
      Drug Metabolism and Disposition March 2009, 37 (3) 479-493; DOI: https://doi.org/10.1124/dmd.108.024364
  3. Schlicht, Kari E.

    1. You have access
      Effect of CYP2A13 Active Site Mutation N297A on Metabolism of Coumarin and Tobacco-Specific Nitrosamines
      Kari E. Schlicht, Jeannette Zinggeler Berg and Sharon E. Murphy
      Drug Metabolism and Disposition March 2009, 37 (3) 665-671; DOI: https://doi.org/10.1124/dmd.108.025072
  4. Shaik, Naveed

    1. You have access
      Substrate-Dependent Breast Cancer Resistance Protein (Bcrp1/Abcg2)-Mediated Interactions: Consideration of Multiple Binding Sites in in Vitro Assay Design
      Nagdeep Giri, Sagar Agarwal, Naveed Shaik, Guoyu Pan, Ying Chen and William F. Elmquist
      Drug Metabolism and Disposition March 2009, 37 (3) 560-570; DOI: https://doi.org/10.1124/dmd.108.022046
  5. Shen, Hong-Wu

    1. You have access
      Pinoline May be Used as a Probe for CYP2D6 Activity
      Xi-Ling Jiang, Hong-Wu Shen and Ai-Ming Yu
      Drug Metabolism and Disposition March 2009, 37 (3) 443-446; DOI: https://doi.org/10.1124/dmd.108.025056
  6. Shipitsin, Alexander V.

    1. You have access
      5′-Aminocarbonyl Phosphonates as New Zidovudine Depot Forms: Antiviral Properties, Intracellular Transformations, and Pharmacokinetic Parameters
      Anastasia L. Khandazhinskaya, Dmitry V. Yanvarev, Maxim V. Jasko, Alexander V. Shipitsin, Vsevolod A. Khalizev, Stanislav I. Shram, Yuriy S. Skoblov, Elena A. Shirokova and Marina K. Kukhanova
      Drug Metabolism and Disposition March 2009, 37 (3) 494-501; DOI: https://doi.org/10.1124/dmd.108.022269
  7. Shirai, Nobuaki

    1. You have access
      Carrier-Mediated Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small-Molecule Survivin Suppressant, into Human Solid Tumor and Lymphoma Cells
      Tsuyoshi Minematsu, Megumi Iwai, Kenji Sugimoto, Nobuaki Shirai, Takahito Nakahara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition March 2009, 37 (3) 619-628; DOI: https://doi.org/10.1124/dmd.108.025254
  8. Shirokova, Elena A.

    1. You have access
      5′-Aminocarbonyl Phosphonates as New Zidovudine Depot Forms: Antiviral Properties, Intracellular Transformations, and Pharmacokinetic Parameters
      Anastasia L. Khandazhinskaya, Dmitry V. Yanvarev, Maxim V. Jasko, Alexander V. Shipitsin, Vsevolod A. Khalizev, Stanislav I. Shram, Yuriy S. Skoblov, Elena A. Shirokova and Marina K. Kukhanova
      Drug Metabolism and Disposition March 2009, 37 (3) 494-501; DOI: https://doi.org/10.1124/dmd.108.022269
  9. Shram, Stanislav I.

    1. You have access
      5′-Aminocarbonyl Phosphonates as New Zidovudine Depot Forms: Antiviral Properties, Intracellular Transformations, and Pharmacokinetic Parameters
      Anastasia L. Khandazhinskaya, Dmitry V. Yanvarev, Maxim V. Jasko, Alexander V. Shipitsin, Vsevolod A. Khalizev, Stanislav I. Shram, Yuriy S. Skoblov, Elena A. Shirokova and Marina K. Kukhanova
      Drug Metabolism and Disposition March 2009, 37 (3) 494-501; DOI: https://doi.org/10.1124/dmd.108.022269
  10. Si, Dayong

    1. You have access
      Mechanism of CYP2C9 Inhibition by Flavones and Flavonols
      Dayong Si, Ying Wang, Yi-Han Zhou, Yingjie Guo, Juan Wang, Hui Zhou, Ze-Sheng Li and J. Paul Fawcett
      Drug Metabolism and Disposition March 2009, 37 (3) 629-634; DOI: https://doi.org/10.1124/dmd.108.023416
  11. Siegmund, Werner

    1. You have access
      Investigation of the in Vitro Metabolism of the Analgesic Flupirtine
      Karen Methling, Przyemslaw Reszka, Michael Lalk, Oldrich Vrana, Eberhard Scheuch, Werner Siegmund, Bernd Terhaag and Patrick J. Bednarski
      Drug Metabolism and Disposition March 2009, 37 (3) 479-493; DOI: https://doi.org/10.1124/dmd.108.024364
  12. Silverman, Jeffrey A.

    1. You have access
      Metabolism of (+)-1,4-Dihydro-7-(trans-3-methoxy-4-methylamino-1-pyrrolidinyl)-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic Acid (Voreloxin; Formerly SNS-595), a Novel Replication-Dependent DNA-Damaging Agent
      Marc J. Evanchik, Darin Allen, Josh C. Yoburn, Jeffrey A. Silverman and Ute Hoch
      Drug Metabolism and Disposition March 2009, 37 (3) 594-601; DOI: https://doi.org/10.1124/dmd.108.023432
  13. Skoblov, Yuriy S.

    1. You have access
      5′-Aminocarbonyl Phosphonates as New Zidovudine Depot Forms: Antiviral Properties, Intracellular Transformations, and Pharmacokinetic Parameters
      Anastasia L. Khandazhinskaya, Dmitry V. Yanvarev, Maxim V. Jasko, Alexander V. Shipitsin, Vsevolod A. Khalizev, Stanislav I. Shram, Yuriy S. Skoblov, Elena A. Shirokova and Marina K. Kukhanova
      Drug Metabolism and Disposition March 2009, 37 (3) 494-501; DOI: https://doi.org/10.1124/dmd.108.022269
  14. Smith, Harold

    1. You have access
      Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Yannick Batard, Lai Wang, Heidi Einolf, Helen Gu, James B. Mangold, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 536-544; DOI: https://doi.org/10.1124/dmd.108.023010
    2. You have access
      Disposition of Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Rats and Dogs
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Dennis Flood, Roger Kramp, Ron Filipeck, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 545-554; DOI: https://doi.org/10.1124/dmd.108.023002
  15. Stieger, Bruno

    1. You have access
      Regulation of Drug Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokines Tumor Necrosis Factor-α or Interleukin-6
      Marc Le Vee, Valérie Lecureur, Bruno Stieger and Olivier Fardel
      Drug Metabolism and Disposition March 2009, 37 (3) 685-693; DOI: https://doi.org/10.1124/dmd.108.023630
  16. Sugimoto, Kenji

    1. You have access
      Carrier-Mediated Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small-Molecule Survivin Suppressant, into Human Solid Tumor and Lymphoma Cells
      Tsuyoshi Minematsu, Megumi Iwai, Kenji Sugimoto, Nobuaki Shirai, Takahito Nakahara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition March 2009, 37 (3) 619-628; DOI: https://doi.org/10.1124/dmd.108.025254
  17. Sugiura, Mikihiro

    1. You have access
      Investigation of the Role of Oligopeptide Transporter PEPT1 and Sodium/Glucose Cotransporter SGLT1 in Intestinal Absorption of Their Substrates Using Small GTP-Binding Protein Rab8-Null Mice
      Yukio Kato, Tomoko Sugiura, Yasuhito Nakadera, Mikihiro Sugiura, Yoshiyuki Kubo, Takashi Sato, Akihiro Harada and Akira Tsuji
      Drug Metabolism and Disposition March 2009, 37 (3) 602-607; DOI: https://doi.org/10.1124/dmd.108.023689
  18. Sugiura, Tomoko

    1. You have access
      Investigation of the Role of Oligopeptide Transporter PEPT1 and Sodium/Glucose Cotransporter SGLT1 in Intestinal Absorption of Their Substrates Using Small GTP-Binding Protein Rab8-Null Mice
      Yukio Kato, Tomoko Sugiura, Yasuhito Nakadera, Mikihiro Sugiura, Yoshiyuki Kubo, Takashi Sato, Akihiro Harada and Akira Tsuji
      Drug Metabolism and Disposition March 2009, 37 (3) 602-607; DOI: https://doi.org/10.1124/dmd.108.023689
  19. Sugiyama, Yuichi

    1. You have access
      The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
      Soichiro Matsushima, Kazuya Maeda, Katsuhisa Inoue, Kin-ya Ohta, Hiroaki Yuasa, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2009, 37 (3) 555-559; DOI: https://doi.org/10.1124/dmd.108.023911
  20. Sun, Hao

    1. You have access
      Dehydrogenation of the Indoline-Containing Drug 4-Chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (Indapamide) by CYP3A4: Correlation with in Silico Predictions
      Hao Sun, Chad Moore, Patrick M. Dansette, Santosh Kumar, James R. Halpert and Garold S. Yost
      Drug Metabolism and Disposition March 2009, 37 (3) 672-684; DOI: https://doi.org/10.1124/dmd.108.022707
  21. Syvänen, Stina

    1. You have access
      Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
      Stina Syvänen, Örjan Lindhe, Mikael Palner, Birgitte R. Kornum, Obaidur Rahman, Bengt Långström, Gitte M. Knudsen and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition March 2009, 37 (3) 635-643; DOI: https://doi.org/10.1124/dmd.108.024745

T

  1. Taboureau, Olivier

    1. You have access
      Classification of Cytochrome P450 1A2 Inhibitors and Noninhibitors by Machine Learning Techniques
      Poongavanam Vasanthanathan, Olivier Taboureau, Chris Oostenbrink, Nico P. E. Vermeulen, Lars Olsen and Flemming Steen Jørgensen
      Drug Metabolism and Disposition March 2009, 37 (3) 658-664; DOI: https://doi.org/10.1124/dmd.108.023507
  2. Tai, Jenny K.

    1. You have access
      Developmental Expression and Endocrine Regulation of CYP1B1 in Rat Testis
      Grace S. Leung, Masahiko Kawai, Jenny K. Tai, Jie Chen, Stelvio M. Bandiera and Thomas K. H. Chang
      Drug Metabolism and Disposition March 2009, 37 (3) 523-528; DOI: https://doi.org/10.1124/dmd.108.025635
  3. Tajima, Masami

    1. You have access
      Mechanism-Based Inhibition of Human Cytochrome P450 2B6 by Ticlopidine, Clopidogrel, and the Thiolactone Metabolite of Prasugrel
      Yumi Nishiya, Katsunobu Hagihara, Takashi Ito, Masami Tajima, Shin-ichi Miura, Atsushi Kurihara, Nagy A. Farid and Toshihiko Ikeda
      Drug Metabolism and Disposition March 2009, 37 (3) 589-593; DOI: https://doi.org/10.1124/dmd.108.022988
  4. Talakad, Jyothi C.

    1. You have access
      Decreased Susceptibility of the Cytochrome P450 2B6 Variant K262R to Inhibition by Several Clinically Important Drugs
      Jyothi C. Talakad, Santosh Kumar and James R. Halpert
      Drug Metabolism and Disposition March 2009, 37 (3) 644-650; DOI: https://doi.org/10.1124/dmd.108.023655
  5. Terhaag, Bernd

    1. You have access
      Investigation of the in Vitro Metabolism of the Analgesic Flupirtine
      Karen Methling, Przyemslaw Reszka, Michael Lalk, Oldrich Vrana, Eberhard Scheuch, Werner Siegmund, Bernd Terhaag and Patrick J. Bednarski
      Drug Metabolism and Disposition March 2009, 37 (3) 479-493; DOI: https://doi.org/10.1124/dmd.108.024364
  6. Tonn, George R.

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  7. Tran, Phi

    1. You have access
      Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Yannick Batard, Lai Wang, Heidi Einolf, Helen Gu, James B. Mangold, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 536-544; DOI: https://doi.org/10.1124/dmd.108.023010
    2. You have access
      Disposition of Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Rats and Dogs
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Dennis Flood, Roger Kramp, Ron Filipeck, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 545-554; DOI: https://doi.org/10.1124/dmd.108.023002
  8. Tsuji, Akira

    1. You have access
      Investigation of the Role of Oligopeptide Transporter PEPT1 and Sodium/Glucose Cotransporter SGLT1 in Intestinal Absorption of Their Substrates Using Small GTP-Binding Protein Rab8-Null Mice
      Yukio Kato, Tomoko Sugiura, Yasuhito Nakadera, Mikihiro Sugiura, Yoshiyuki Kubo, Takashi Sato, Akihiro Harada and Akira Tsuji
      Drug Metabolism and Disposition March 2009, 37 (3) 602-607; DOI: https://doi.org/10.1124/dmd.108.023689

U

  1. Uehara, Shotaro

    1. You have access
      Sex-Related Differences in the Expression of mfGSTA2, a Novel GST Identified in Cynomolgus Monkey (Macaca fascicularis)
      Yasuhiro Uno, Tsukasa Ohuchi, Shotaro Uehara, Go Kito, Tetsuya Kamataki and Ryoichi Nagata
      Drug Metabolism and Disposition March 2009, 37 (3) 453-456; DOI: https://doi.org/10.1124/dmd.108.023747
  2. Uno, Yasuhiro

    1. You have access
      Sex-Related Differences in the Expression of mfGSTA2, a Novel GST Identified in Cynomolgus Monkey (Macaca fascicularis)
      Yasuhiro Uno, Tsukasa Ohuchi, Shotaro Uehara, Go Kito, Tetsuya Kamataki and Ryoichi Nagata
      Drug Metabolism and Disposition March 2009, 37 (3) 453-456; DOI: https://doi.org/10.1124/dmd.108.023747
  3. Usui, Takashi

    1. You have access
      Carrier-Mediated Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small-Molecule Survivin Suppressant, into Human Solid Tumor and Lymphoma Cells
      Tsuyoshi Minematsu, Megumi Iwai, Kenji Sugimoto, Nobuaki Shirai, Takahito Nakahara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition March 2009, 37 (3) 619-628; DOI: https://doi.org/10.1124/dmd.108.025254

V

  1. Van Lengerich, Bettina

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  2. Vasanthanathan, Poongavanam

    1. You have access
      Classification of Cytochrome P450 1A2 Inhibitors and Noninhibitors by Machine Learning Techniques
      Poongavanam Vasanthanathan, Olivier Taboureau, Chris Oostenbrink, Nico P. E. Vermeulen, Lars Olsen and Flemming Steen Jørgensen
      Drug Metabolism and Disposition March 2009, 37 (3) 658-664; DOI: https://doi.org/10.1124/dmd.108.023507
  3. Vee, Marc Le

    1. You have access
      Regulation of Drug Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokines Tumor Necrosis Factor-α or Interleukin-6
      Marc Le Vee, Valérie Lecureur, Bruno Stieger and Olivier Fardel
      Drug Metabolism and Disposition March 2009, 37 (3) 685-693; DOI: https://doi.org/10.1124/dmd.108.023630
  4. Vermeulen, Nico P. E.

    1. You have access
      Classification of Cytochrome P450 1A2 Inhibitors and Noninhibitors by Machine Learning Techniques
      Poongavanam Vasanthanathan, Olivier Taboureau, Chris Oostenbrink, Nico P. E. Vermeulen, Lars Olsen and Flemming Steen Jørgensen
      Drug Metabolism and Disposition March 2009, 37 (3) 658-664; DOI: https://doi.org/10.1124/dmd.108.023507
  5. Voice, Michael

    1. You have access
      Evaluation of Escherichia coli Membrane Preparations of Canine CYP1A1, 2B11, 2C21, 2C41, 2D15, 3A12, and 3A26 with Coexpressed Canine Cytochrome P450 Reductase
      Charles W. Locuson, Brian T. Ethell, Michael Voice, David Lee and Kenneth L. Feenstra
      Drug Metabolism and Disposition March 2009, 37 (3) 457-461; DOI: https://doi.org/10.1124/dmd.108.025312
  6. Vrana, Oldrich

    1. You have access
      Investigation of the in Vitro Metabolism of the Analgesic Flupirtine
      Karen Methling, Przyemslaw Reszka, Michael Lalk, Oldrich Vrana, Eberhard Scheuch, Werner Siegmund, Bernd Terhaag and Patrick J. Bednarski
      Drug Metabolism and Disposition March 2009, 37 (3) 479-493; DOI: https://doi.org/10.1124/dmd.108.024364

W

  1. Wang, Juan

    1. You have access
      Mechanism of CYP2C9 Inhibition by Flavones and Flavonols
      Dayong Si, Ying Wang, Yi-Han Zhou, Yingjie Guo, Juan Wang, Hui Zhou, Ze-Sheng Li and J. Paul Fawcett
      Drug Metabolism and Disposition March 2009, 37 (3) 629-634; DOI: https://doi.org/10.1124/dmd.108.023416
  2. Wang, Lai

    1. You have access
      Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Yannick Batard, Lai Wang, Heidi Einolf, Helen Gu, James B. Mangold, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 536-544; DOI: https://doi.org/10.1124/dmd.108.023010
  3. Wang, Xuemei

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  4. Wang, Ying

    1. You have access
      Mechanism of CYP2C9 Inhibition by Flavones and Flavonols
      Dayong Si, Ying Wang, Yi-Han Zhou, Yingjie Guo, Juan Wang, Hui Zhou, Ze-Sheng Li and J. Paul Fawcett
      Drug Metabolism and Disposition March 2009, 37 (3) 629-634; DOI: https://doi.org/10.1124/dmd.108.023416
  5. Weidolf, Lars

    1. You have access
      Novel Metabolites of Amodiaquine Formed by CYP1A1 and CYP1B1: Structure Elucidation Using Electrochemistry, Mass Spectrometry, and NMR
      Tove Johansson, Ulrik Jurva, Gunnar Grönberg, Lars Weidolf and Collen Masimirembwa
      Drug Metabolism and Disposition March 2009, 37 (3) 571-579; DOI: https://doi.org/10.1124/dmd.108.025171
  6. Wong, Bradley K.

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  7. Wong, Simon G.

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931
  8. Wong, Sylvia C.

    1. You have access
      An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
      George R. Tonn, Simon G. Wong, Sylvia C. Wong, Michael G. Johnson, Ji Ma, Robert Cho, Leslie C. Floren, Kathryn Kersey, Karen Berry, Andrew P. Marcus, Xuemei Wang, Bettina Van Lengerich, Julio C. Medina, Paul G. Pearson and Bradley K. Wong
      Drug Metabolism and Disposition March 2009, 37 (3) 502-513; DOI: https://doi.org/10.1124/dmd.108.021931

Y

  1. Yan, Zhixia

    1. You have access
      Identification of a Cranberry Juice Product that Inhibits Enteric CYP3A-Mediated First-Pass Metabolism in Humans
      Ngoc Ngo, Zhixia Yan, Tyler N. Graf, Daniel R. Carrizosa, Angela D. M. Kashuba, E. Claire Dees, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition March 2009, 37 (3) 514-522; DOI: https://doi.org/10.1124/dmd.108.024968
  2. Yanni, Souzan B.

    1. You have access
      Fexofenadine Brain Exposure and the Influence of Blood-Brain Barrier P-Glycoprotein After Fexofenadine and Terfenadine Administration
      Rong Zhao, J. Cory Kalvass, Souzan B. Yanni, Arlene S. Bridges and Gary M. Pollack
      Drug Metabolism and Disposition March 2009, 37 (3) 529-535; DOI: https://doi.org/10.1124/dmd.107.019893
  3. Yanvarev, Dmitry V.

    1. You have access
      5′-Aminocarbonyl Phosphonates as New Zidovudine Depot Forms: Antiviral Properties, Intracellular Transformations, and Pharmacokinetic Parameters
      Anastasia L. Khandazhinskaya, Dmitry V. Yanvarev, Maxim V. Jasko, Alexander V. Shipitsin, Vsevolod A. Khalizev, Stanislav I. Shram, Yuriy S. Skoblov, Elena A. Shirokova and Marina K. Kukhanova
      Drug Metabolism and Disposition March 2009, 37 (3) 494-501; DOI: https://doi.org/10.1124/dmd.108.022269
  4. Yin, Hequn

    1. You have access
      Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Yannick Batard, Lai Wang, Heidi Einolf, Helen Gu, James B. Mangold, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 536-544; DOI: https://doi.org/10.1124/dmd.108.023010
    2. You have access
      Disposition of Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Rats and Dogs
      Handan He, Phi Tran, Hequn Yin, Harold Smith, Dennis Flood, Roger Kramp, Ron Filipeck, Volker Fischer and Dan Howard
      Drug Metabolism and Disposition March 2009, 37 (3) 545-554; DOI: https://doi.org/10.1124/dmd.108.023002
  5. Yoburn, Josh C.

    1. You have access
      Metabolism of (+)-1,4-Dihydro-7-(trans-3-methoxy-4-methylamino-1-pyrrolidinyl)-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic Acid (Voreloxin; Formerly SNS-595), a Novel Replication-Dependent DNA-Damaging Agent
      Marc J. Evanchik, Darin Allen, Josh C. Yoburn, Jeffrey A. Silverman and Ute Hoch
      Drug Metabolism and Disposition March 2009, 37 (3) 594-601; DOI: https://doi.org/10.1124/dmd.108.023432
  6. Yost, Garold S.

    1. You have access
      Dehydrogenation of the Indoline-Containing Drug 4-Chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (Indapamide) by CYP3A4: Correlation with in Silico Predictions
      Hao Sun, Chad Moore, Patrick M. Dansette, Santosh Kumar, James R. Halpert and Garold S. Yost
      Drug Metabolism and Disposition March 2009, 37 (3) 672-684; DOI: https://doi.org/10.1124/dmd.108.022707
  7. Yu, Ai-Ming

    1. You have access
      Pinoline May be Used as a Probe for CYP2D6 Activity
      Xi-Ling Jiang, Hong-Wu Shen and Ai-Ming Yu
      Drug Metabolism and Disposition March 2009, 37 (3) 443-446; DOI: https://doi.org/10.1124/dmd.108.025056
  8. Yuasa, Hiroaki

    1. You have access
      The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
      Soichiro Matsushima, Kazuya Maeda, Katsuhisa Inoue, Kin-ya Ohta, Hiroaki Yuasa, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2009, 37 (3) 555-559; DOI: https://doi.org/10.1124/dmd.108.023911

Z

  1. Zhang, Jin

    1. You have access
      An Intestinal Epithelium-Specific Cytochrome P450 (P450) Reductase-Knockout Mouse Model: Direct Evidence for a Role of Intestinal P450s in First-Pass Clearance of Oral Nifedipine
      Qing-Yu Zhang, Cheng Fang, Jin Zhang, Deborah Dunbar, Laurence Kaminsky and Xinxin Ding
      Drug Metabolism and Disposition March 2009, 37 (3) 651-657; DOI: https://doi.org/10.1124/dmd.108.025429
  2. Zhang, Jun

    1. You have access
      Hepatic Flavin-Containing Monooxygenase Gene Regulation in Different Mouse Inflammation Models
      Jun Zhang, Madhusudana R. Chaluvadi, Rob Reddy, Meike S. Motika, Terrilyn A. Richardson, John R. Cashman and Edward T. Morgan
      Drug Metabolism and Disposition March 2009, 37 (3) 462-468; DOI: https://doi.org/10.1124/dmd.108.025338
  3. Zhang, Qing-Yu

    1. You have access
      An Intestinal Epithelium-Specific Cytochrome P450 (P450) Reductase-Knockout Mouse Model: Direct Evidence for a Role of Intestinal P450s in First-Pass Clearance of Oral Nifedipine
      Qing-Yu Zhang, Cheng Fang, Jin Zhang, Deborah Dunbar, Laurence Kaminsky and Xinxin Ding
      Drug Metabolism and Disposition March 2009, 37 (3) 651-657; DOI: https://doi.org/10.1124/dmd.108.025429
  4. Zhao, Rong

    1. You have access
      Fexofenadine Brain Exposure and the Influence of Blood-Brain Barrier P-Glycoprotein After Fexofenadine and Terfenadine Administration
      Rong Zhao, J. Cory Kalvass, Souzan B. Yanni, Arlene S. Bridges and Gary M. Pollack
      Drug Metabolism and Disposition March 2009, 37 (3) 529-535; DOI: https://doi.org/10.1124/dmd.107.019893
  5. Zhou, Hui

    1. You have access
      Mechanism of CYP2C9 Inhibition by Flavones and Flavonols
      Dayong Si, Ying Wang, Yi-Han Zhou, Yingjie Guo, Juan Wang, Hui Zhou, Ze-Sheng Li and J. Paul Fawcett
      Drug Metabolism and Disposition March 2009, 37 (3) 629-634; DOI: https://doi.org/10.1124/dmd.108.023416
  6. Zhou, Yi-Han

    1. You have access
      Mechanism of CYP2C9 Inhibition by Flavones and Flavonols
      Dayong Si, Ying Wang, Yi-Han Zhou, Yingjie Guo, Juan Wang, Hui Zhou, Ze-Sheng Li and J. Paul Fawcett
      Drug Metabolism and Disposition March 2009, 37 (3) 629-634; DOI: https://doi.org/10.1124/dmd.108.023416
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Drug Metabolism and Disposition: 37 (3)
Drug Metabolism and Disposition
Vol. 37, Issue 3
1 Mar 2009
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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