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Research ArticleArticle

Sulfation of O-Demethyl Apixaban: Enzyme Identification and Species Comparison

Lifei Wang, Nirmala Raghavan, Kan He, Joseph M. Luettgen, W. Griffith Humphreys, Robert M. Knabb, Donald J. Pinto and Donglu Zhang
Drug Metabolism and Disposition April 2009, 37 (4) 802-808; DOI: https://doi.org/10.1124/dmd.108.025593

Article Information

vol. 37 no. 4 802-808
DOI 
https://doi.org/10.1124/dmd.108.025593
PubMed 
19131519
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received November 11, 2008
  • Accepted January 7, 2009
  • Published online March 19, 2009.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Lifei Wang,
  2. Nirmala Raghavan,
  3. Kan He,
  4. Joseph M. Luettgen,
  5. W. Griffith Humphreys,
  6. Robert M. Knabb,
  7. Donald J. Pinto and
  8. Donglu Zhang
  1. Pharmaceutical Candidate Optimization (L.W., N.R., K.H., W.G.H., D.Z.), Discovery Biology (J.M.L., R.M.K.), and Chemistry (D.J.P.), Bristol-Myers Squibb Research and Development, Princeton, New Jersey
  1. Address correspondence to:
    Donglu Zhang, Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, P.O. Box 4000, Princeton, NJ 08543. E-mail: donglu.zhang{at}bms.com
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Research ArticleArticle

Sulfation of O-Demethyl Apixaban: Enzyme Identification and Species Comparison

Lifei Wang, Nirmala Raghavan, Kan He, Joseph M. Luettgen, W. Griffith Humphreys, Robert M. Knabb, Donald J. Pinto and Donglu Zhang
Drug Metabolism and Disposition April 1, 2009, 37 (4) 802-808; DOI: https://doi.org/10.1124/dmd.108.025593
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