Index by author
July 01, 2009; Volume 37,Issue 7
A
Akiyama, Y.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Almeida, Bruno
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Ando, Y.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Anraku, Makoto
- You have accessPharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen CarrierKazuaki Taguchi, Yukino Urata, Makoto Anraku, Toru Maruyama, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toshiya Kai and Masaki OtagiriDrug Metabolism and Disposition July 2009, 37 (7) 1456-1463; DOI: https://doi.org/10.1124/dmd.109.027094
Aoki, Yasuhiro
- You have accessHuman Arylacetamide Deacetylase Is a Principal Enzyme in Flutamide HydrolysisAkinobu Watanabe, Tatsuki Fukami, Miki Nakajima, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi YokoiDrug Metabolism and Disposition July 2009, 37 (7) 1513-1520; DOI: https://doi.org/10.1124/dmd.109.026567
Apparsundaram, Subbu
- You have accessUnbound Brain Concentration Determines Receptor Occupancy: A Correlation of Drug Concentration and Brain Serotonin and Dopamine Reuptake Transporter Occupancy for Eighteen Compounds in RatsXingrong Liu, Olga Vilenski, Joyce Kwan, Subbu Apparsundaram and Robert WeikertDrug Metabolism and Disposition July 2009, 37 (7) 1548-1556; DOI: https://doi.org/10.1124/dmd.109.026674
Araki, K.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
B
Baldwin, R. Michael
- You have accessRegulation of Human CYP2C18 and CYP2C19 in Transgenic Mice: Influence of Castration, Testosterone, and Growth HormoneSusanne Löfgren, R. Michael Baldwin, Margareta Carlerös, Ylva Terelius, Ronny Fransson-Steen, Jessica Mwinyi, David J. Waxman and Magnus Ingelman-SundbergDrug Metabolism and Disposition July 2009, 37 (7) 1505-1512; DOI: https://doi.org/10.1124/dmd.109.026963
Beaune, Philippe
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Bièche, Ivan
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Blomgren, Anders L.
- You have accessBudesonide and Ciclesonide: Effect of Tissue Binding on Pulmonary Receptor BindingKai Wu, Anders L. Blomgren, Kjell Ekholm, Benjamin Weber, Staffan Edsbaecker and Günther HochhausDrug Metabolism and Disposition July 2009, 37 (7) 1421-1426; DOI: https://doi.org/10.1124/dmd.108.026039
Bratton, Stacie M.
- You have accessCharacterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic CannabinoidsAnna Mazur, Cheryl F. Lichti, Paul L. Prather, Agnieszka K. Zielinska, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska-Pandya and Jeffery H. MoranDrug Metabolism and Disposition July 2009, 37 (7) 1496-1504; DOI: https://doi.org/10.1124/dmd.109.026898
C
Calle, Ángela P.
- You have accessEffects of Plantago ovata Husk on Levodopa (with Carbidopa) Bioavailability in Rabbits with Autonomic Gastrointestinal DisordersJuan J. García, Nélida Fernández, Ángela P. Calle, M. José Diez, Ana Sahagún and Matilde SierraDrug Metabolism and Disposition July 2009, 37 (7) 1434-1442; DOI: https://doi.org/10.1124/dmd.108.026229
Carlerös, Margareta
- You have accessRegulation of Human CYP2C18 and CYP2C19 in Transgenic Mice: Influence of Castration, Testosterone, and Growth HormoneSusanne Löfgren, R. Michael Baldwin, Margareta Carlerös, Ylva Terelius, Ronny Fransson-Steen, Jessica Mwinyi, David J. Waxman and Magnus Ingelman-SundbergDrug Metabolism and Disposition July 2009, 37 (7) 1505-1512; DOI: https://doi.org/10.1124/dmd.109.026963
Chen, Yuan
- You have accessMetabolic Activation of Nevirapine in Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4Bo Wen, Yuan Chen and William L. FitchDrug Metabolism and Disposition July 2009, 37 (7) 1557-1562; DOI: https://doi.org/10.1124/dmd.108.024851
Chu, Valeria
- You have accessIn Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America PerspectiveValeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej SkerjanecDrug Metabolism and Disposition July 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029
Cloarec, Olivier
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Cole, Susan P. C.
- You have accessMolecular Basis for Reduced Estrone Sulfate Transport and Altered Modulator Sensitivity of Transmembrane Helix (TM) 6 and TM17 Mutants of Multidrug Resistance Protein 1 (ABCC1)Kazuma Maeno, Akio Nakajima, Gwenaëlle Conseil, Alice Rothnie, Roger G. Deeley and Susan P. C. ColeDrug Metabolism and Disposition July 2009, 37 (7) 1411-1420; DOI: https://doi.org/10.1124/dmd.109.026633
Conseil, Gwenaëlle
- You have accessMolecular Basis for Reduced Estrone Sulfate Transport and Altered Modulator Sensitivity of Transmembrane Helix (TM) 6 and TM17 Mutants of Multidrug Resistance Protein 1 (ABCC1)Kazuma Maeno, Akio Nakajima, Gwenaëlle Conseil, Alice Rothnie, Roger G. Deeley and Susan P. C. ColeDrug Metabolism and Disposition July 2009, 37 (7) 1411-1420; DOI: https://doi.org/10.1124/dmd.109.026633
Cui, Dapeng
- You have accessThe Drug of Abuse γ-Hydroxybutyrate Is a Substrate for Sodium-Coupled Monocarboxylate Transporter (SMCT) 1 (SLC5A8): Characterization of SMCT-Mediated Uptake and InhibitionDapeng Cui and Marilyn E. MorrisDrug Metabolism and Disposition July 2009, 37 (7) 1404-1410; DOI: https://doi.org/10.1124/dmd.109.027169
Cuyàs, Elisabet
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
D
Dauchy, Sandrine
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Declèves, Xavier
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Deeley, Roger G.
- You have accessMolecular Basis for Reduced Estrone Sulfate Transport and Altered Modulator Sensitivity of Transmembrane Helix (TM) 6 and TM17 Mutants of Multidrug Resistance Protein 1 (ABCC1)Kazuma Maeno, Akio Nakajima, Gwenaëlle Conseil, Alice Rothnie, Roger G. Deeley and Susan P. C. ColeDrug Metabolism and Disposition July 2009, 37 (7) 1411-1420; DOI: https://doi.org/10.1124/dmd.109.026633
de la Torre, Rafael
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
de Waziers, Isabelle
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Diez, M. José
- You have accessEffects of Plantago ovata Husk on Levodopa (with Carbidopa) Bioavailability in Rabbits with Autonomic Gastrointestinal DisordersJuan J. García, Nélida Fernández, Ángela P. Calle, M. José Diez, Ana Sahagún and Matilde SierraDrug Metabolism and Disposition July 2009, 37 (7) 1434-1442; DOI: https://doi.org/10.1124/dmd.108.026229
Diry, Monique
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Döhrel, Juliane
- You have accessInfluence of the Cyp1B1 L432V Gene Polymorphism and Exposure to Tobacco Smoke on Cyp1B1 mRNA Expression in Human LeukocytesSimone Helmig, Bahar Hadzaad, Juliane Döhrel and Joachim SchneiderDrug Metabolism and Disposition July 2009, 37 (7) 1490-1495; DOI: https://doi.org/10.1124/dmd.109.027060
Dutheil, Fabien
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Duyckaerts, Charles
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
E
Edsbaecker, Staffan
- You have accessBudesonide and Ciclesonide: Effect of Tissue Binding on Pulmonary Receptor BindingKai Wu, Anders L. Blomgren, Kjell Ekholm, Benjamin Weber, Staffan Edsbaecker and Günther HochhausDrug Metabolism and Disposition July 2009, 37 (7) 1421-1426; DOI: https://doi.org/10.1124/dmd.108.026039
Einolf, Heidi J.
- You have accessIn Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America PerspectiveValeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej SkerjanecDrug Metabolism and Disposition July 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Ekholm, Kjell
- You have accessBudesonide and Ciclesonide: Effect of Tissue Binding on Pulmonary Receptor BindingKai Wu, Anders L. Blomgren, Kjell Ekholm, Benjamin Weber, Staffan Edsbaecker and Günther HochhausDrug Metabolism and Disposition July 2009, 37 (7) 1421-1426; DOI: https://doi.org/10.1124/dmd.108.026039
Endo, H.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Evers, Raymond
- You have accessIn Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America PerspectiveValeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej SkerjanecDrug Metabolism and Disposition July 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029
F
Farré, Magí
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Fernández, Nélida
- You have accessEffects of Plantago ovata Husk on Levodopa (with Carbidopa) Bioavailability in Rabbits with Autonomic Gastrointestinal DisordersJuan J. García, Nélida Fernández, Ángela P. Calle, M. José Diez, Ana Sahagún and Matilde SierraDrug Metabolism and Disposition July 2009, 37 (7) 1434-1442; DOI: https://doi.org/10.1124/dmd.108.026229
Finel, Moshe
- You have accessCharacterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic CannabinoidsAnna Mazur, Cheryl F. Lichti, Paul L. Prather, Agnieszka K. Zielinska, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska-Pandya and Jeffery H. MoranDrug Metabolism and Disposition July 2009, 37 (7) 1496-1504; DOI: https://doi.org/10.1124/dmd.109.026898
Fitch, William L.
- You have accessMetabolic Activation of Nevirapine in Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4Bo Wen, Yuan Chen and William L. FitchDrug Metabolism and Disposition July 2009, 37 (7) 1557-1562; DOI: https://doi.org/10.1124/dmd.108.024851
Flinois, Jean-Pierre
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Fransson-Steen, Ronny
- You have accessRegulation of Human CYP2C18 and CYP2C19 in Transgenic Mice: Influence of Castration, Testosterone, and Growth HormoneSusanne Löfgren, R. Michael Baldwin, Margareta Carlerös, Ylva Terelius, Ronny Fransson-Steen, Jessica Mwinyi, David J. Waxman and Magnus Ingelman-SundbergDrug Metabolism and Disposition July 2009, 37 (7) 1505-1512; DOI: https://doi.org/10.1124/dmd.109.026963
Fujita, K.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Fukami, Tatsuki
- You have accessHuman Arylacetamide Deacetylase Is a Principal Enzyme in Flutamide HydrolysisAkinobu Watanabe, Tatsuki Fukami, Miki Nakajima, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi YokoiDrug Metabolism and Disposition July 2009, 37 (7) 1513-1520; DOI: https://doi.org/10.1124/dmd.109.026567
G
Gallus-Zawada, Anna
- You have accessCharacterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic CannabinoidsAnna Mazur, Cheryl F. Lichti, Paul L. Prather, Agnieszka K. Zielinska, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska-Pandya and Jeffery H. MoranDrug Metabolism and Disposition July 2009, 37 (7) 1496-1504; DOI: https://doi.org/10.1124/dmd.109.026898
García, Juan J.
- You have accessEffects of Plantago ovata Husk on Levodopa (with Carbidopa) Bioavailability in Rabbits with Autonomic Gastrointestinal DisordersJuan J. García, Nélida Fernández, Ángela P. Calle, M. José Diez, Ana Sahagún and Matilde SierraDrug Metabolism and Disposition July 2009, 37 (7) 1434-1442; DOI: https://doi.org/10.1124/dmd.108.026229
Gavrilova, Olga
- You have accessThe Role of P-Glycoprotein in Limiting Brain Penetration of the Peripherally Acting Anticholinergic Overactive Bladder Drug Trospium ChlorideJoachim Geyer, Olga Gavrilova and Ernst PetzingerDrug Metabolism and Disposition July 2009, 37 (7) 1371-1374; DOI: https://doi.org/10.1124/dmd.109.027144
Geyer, Joachim
- You have accessThe Role of P-Glycoprotein in Limiting Brain Penetration of the Peripherally Acting Anticholinergic Overactive Bladder Drug Trospium ChlorideJoachim Geyer, Olga Gavrilova and Ernst PetzingerDrug Metabolism and Disposition July 2009, 37 (7) 1371-1374; DOI: https://doi.org/10.1124/dmd.109.027144
Grimm, Scott W.
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
H
Hadzaad, Bahar
- You have accessInfluence of the Cyp1B1 L432V Gene Polymorphism and Exposure to Tobacco Smoke on Cyp1B1 mRNA Expression in Human LeukocytesSimone Helmig, Bahar Hadzaad, Juliane Döhrel and Joachim SchneiderDrug Metabolism and Disposition July 2009, 37 (7) 1490-1495; DOI: https://doi.org/10.1124/dmd.109.027060
Hall, Steven D.
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Hayashi, Mike
- You have accessIn Vitro Metabolism of the Novel, Highly Selective Oral Angiogenesis Inhibitor Motesanib Diphosphate in Preclinical Species and in HumansChun Li, Mita Kuchimanchi, Dean Hickman, Leszek Poppe, Mike Hayashi, Yihong Zhou, Raju Subramanian, Gondi Kumar and Sekhar SurapaneniDrug Metabolism and Disposition July 2009, 37 (7) 1378-1394; DOI: https://doi.org/10.1124/dmd.108.025742
He, Kan
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Helmig, Simone
- You have accessInfluence of the Cyp1B1 L432V Gene Polymorphism and Exposure to Tobacco Smoke on Cyp1B1 mRNA Expression in Human LeukocytesSimone Helmig, Bahar Hadzaad, Juliane Döhrel and Joachim SchneiderDrug Metabolism and Disposition July 2009, 37 (7) 1490-1495; DOI: https://doi.org/10.1124/dmd.109.027060
Henne, Ilana K.
- You have accessBiotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist in Sprague-Dawley Rats and the Dispositional Characterization of Its N-Carbamoyl Glucuronide MetaboliteChristopher L. Shaffer, Tim F. Ryder, Karthik Venkatakrishnan, Ilana K. Henne and Thomas N. O'ConnellDrug Metabolism and Disposition July 2009, 37 (7) 1480-1489; DOI: https://doi.org/10.1124/dmd.109.027037
Hickman, Dean
- You have accessIn Vitro Metabolism of the Novel, Highly Selective Oral Angiogenesis Inhibitor Motesanib Diphosphate in Preclinical Species and in HumansChun Li, Mita Kuchimanchi, Dean Hickman, Leszek Poppe, Mike Hayashi, Yihong Zhou, Raju Subramanian, Gondi Kumar and Sekhar SurapaneniDrug Metabolism and Disposition July 2009, 37 (7) 1378-1394; DOI: https://doi.org/10.1124/dmd.108.025742
Hirose, T.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Hochhaus, Günther
- You have accessBudesonide and Ciclesonide: Effect of Tissue Binding on Pulmonary Receptor BindingKai Wu, Anders L. Blomgren, Kjell Ekholm, Benjamin Weber, Staffan Edsbaecker and Günther HochhausDrug Metabolism and Disposition July 2009, 37 (7) 1421-1426; DOI: https://doi.org/10.1124/dmd.108.026039
Horie, Toshiharu
- You have accessCorrelation between Apical Localization of Abcc2/Mrp2 and Phosphorylation Status of Ezrin in Rat IntestineTakafumi Nakano, Shuichi Sekine, Kousei Ito and Toshiharu HorieDrug Metabolism and Disposition July 2009, 37 (7) 1521-1527; DOI: https://doi.org/10.1124/dmd.108.024836
Horinouchi, Hirohisa
- You have accessPharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen CarrierKazuaki Taguchi, Yukino Urata, Makoto Anraku, Toru Maruyama, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toshiya Kai and Masaki OtagiriDrug Metabolism and Disposition July 2009, 37 (7) 1456-1463; DOI: https://doi.org/10.1124/dmd.109.027094
Horita, Shigeru
- You have accessPrediction of the Hepatic and Renal Clearance of Transporter Substrates in Rats Using in Vitro Uptake ExperimentsTomoko Watanabe, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition July 2009, 37 (7) 1471-1479; DOI: https://doi.org/10.1124/dmd.108.026062
I
Ichikawa, W.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Ingelman-Sundberg, Magnus
- You have accessRegulation of Human CYP2C18 and CYP2C19 in Transgenic Mice: Influence of Castration, Testosterone, and Growth HormoneSusanne Löfgren, R. Michael Baldwin, Margareta Carlerös, Ylva Terelius, Ronny Fransson-Steen, Jessica Mwinyi, David J. Waxman and Magnus Ingelman-SundbergDrug Metabolism and Disposition July 2009, 37 (7) 1505-1512; DOI: https://doi.org/10.1124/dmd.109.026963
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Ishida, H.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Ito, Kousei
- You have accessCorrelation between Apical Localization of Abcc2/Mrp2 and Phosphorylation Status of Ezrin in Rat IntestineTakafumi Nakano, Shuichi Sekine, Kousei Ito and Toshiharu HorieDrug Metabolism and Disposition July 2009, 37 (7) 1521-1527; DOI: https://doi.org/10.1124/dmd.108.024836
Iwatsubo, Takafumi
- You have accessRelationship between Exposure of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a “Funny” If Current Channel Inhibitor, and Heart Rate Reduction in Tachycardia-Induced Beagle DogsKen-ichi Umehara, Kouichi Wada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition July 2009, 37 (7) 1427-1433; DOI: https://doi.org/10.1124/dmd.108.026385
J
Joglar, Jesús
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Jung, Hyun-Ju
- You have accessDiscovery of Novel Functional Variants and Extensive Evaluation of CYP2D6 Genetic Polymorphisms in KoreansSu-Jun Lee, Sang Seop Lee, Hyun-Ju Jung, Ho-Sook Kim, Soo-Jin Park, Chang-Woo Yeo and Jae-Gook ShinDrug Metabolism and Disposition July 2009, 37 (7) 1464-1470; DOI: https://doi.org/10.1124/dmd.108.022368
K
Kai, Toshiya
- You have accessPharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen CarrierKazuaki Taguchi, Yukino Urata, Makoto Anraku, Toru Maruyama, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toshiya Kai and Masaki OtagiriDrug Metabolism and Disposition July 2009, 37 (7) 1456-1463; DOI: https://doi.org/10.1124/dmd.109.027094
Kamimura, Hidetaka
- You have accessRelationship between Exposure of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a “Funny” If Current Channel Inhibitor, and Heart Rate Reduction in Tachycardia-Induced Beagle DogsKen-ichi Umehara, Kouichi Wada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition July 2009, 37 (7) 1427-1433; DOI: https://doi.org/10.1124/dmd.108.026385
Kawara, K.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Khymenets, Olha
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Kim, Ho-Sook
- You have accessDiscovery of Novel Functional Variants and Extensive Evaluation of CYP2D6 Genetic Polymorphisms in KoreansSu-Jun Lee, Sang Seop Lee, Hyun-Ju Jung, Ho-Sook Kim, Soo-Jin Park, Chang-Woo Yeo and Jae-Gook ShinDrug Metabolism and Disposition July 2009, 37 (7) 1464-1470; DOI: https://doi.org/10.1124/dmd.108.022368
Knights, Kathleen M.
- You have accessCharacterization of the Binding of Drugs to Human Intestinal Fatty Acid Binding Protein (IFABP): Potential Role of IFABP as an Alternative to Albumin for in Vitro-in Vivo Extrapolation of Drug Kinetic ParametersAndrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. MinersDrug Metabolism and Disposition July 2009, 37 (7) 1395-1403; DOI: https://doi.org/10.1124/dmd.109.027656
Kobayashi, Koichi
- You have accessPharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen CarrierKazuaki Taguchi, Yukino Urata, Makoto Anraku, Toru Maruyama, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toshiya Kai and Masaki OtagiriDrug Metabolism and Disposition July 2009, 37 (7) 1456-1463; DOI: https://doi.org/10.1124/dmd.109.027094
Kondo, Tsunenori
- You have accessPrediction of the Hepatic and Renal Clearance of Transporter Substrates in Rats Using in Vitro Uptake ExperimentsTomoko Watanabe, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition July 2009, 37 (7) 1471-1479; DOI: https://doi.org/10.1124/dmd.108.026062
Kuchimanchi, Mita
- You have accessIn Vitro Metabolism of the Novel, Highly Selective Oral Angiogenesis Inhibitor Motesanib Diphosphate in Preclinical Species and in HumansChun Li, Mita Kuchimanchi, Dean Hickman, Leszek Poppe, Mike Hayashi, Yihong Zhou, Raju Subramanian, Gondi Kumar and Sekhar SurapaneniDrug Metabolism and Disposition July 2009, 37 (7) 1378-1394; DOI: https://doi.org/10.1124/dmd.108.025742
Kumar, Gondi
- You have accessIn Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America PerspectiveValeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej SkerjanecDrug Metabolism and Disposition July 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029
- You have accessIn Vitro Metabolism of the Novel, Highly Selective Oral Angiogenesis Inhibitor Motesanib Diphosphate in Preclinical Species and in HumansChun Li, Mita Kuchimanchi, Dean Hickman, Leszek Poppe, Mike Hayashi, Yihong Zhou, Raju Subramanian, Gondi Kumar and Sekhar SurapaneniDrug Metabolism and Disposition July 2009, 37 (7) 1378-1394; DOI: https://doi.org/10.1124/dmd.108.025742
Kusuhara, Hiroyuki
- You have accessPrediction of the Hepatic and Renal Clearance of Transporter Substrates in Rats Using in Vitro Uptake ExperimentsTomoko Watanabe, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition July 2009, 37 (7) 1471-1479; DOI: https://doi.org/10.1124/dmd.108.026062
Kwan, Joyce
- You have accessUnbound Brain Concentration Determines Receptor Occupancy: A Correlation of Drug Concentration and Brain Serotonin and Dopamine Reuptake Transporter Occupancy for Eighteen Compounds in RatsXingrong Liu, Olga Vilenski, Joyce Kwan, Subbu Apparsundaram and Robert WeikertDrug Metabolism and Disposition July 2009, 37 (7) 1548-1556; DOI: https://doi.org/10.1124/dmd.109.026674
L
Lai, Yurong
- You have accessEvaluation of in Vitro Models for Screening Alkaline Phosphatase-Mediated Bioconversion of Phosphate Ester ProdrugsHaodan Yuan, Na Li and Yurong LaiDrug Metabolism and Disposition July 2009, 37 (7) 1443-1447; DOI: https://doi.org/10.1124/dmd.108.026245
Lau, Serrine S.
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Lee, Sang Seop
- You have accessDiscovery of Novel Functional Variants and Extensive Evaluation of CYP2D6 Genetic Polymorphisms in KoreansSu-Jun Lee, Sang Seop Lee, Hyun-Ju Jung, Ho-Sook Kim, Soo-Jin Park, Chang-Woo Yeo and Jae-Gook ShinDrug Metabolism and Disposition July 2009, 37 (7) 1464-1470; DOI: https://doi.org/10.1124/dmd.108.022368
Lee, Su-Jun
- You have accessDiscovery of Novel Functional Variants and Extensive Evaluation of CYP2D6 Genetic Polymorphisms in KoreansSu-Jun Lee, Sang Seop Lee, Hyun-Ju Jung, Ho-Sook Kim, Soo-Jin Park, Chang-Woo Yeo and Jae-Gook ShinDrug Metabolism and Disposition July 2009, 37 (7) 1464-1470; DOI: https://doi.org/10.1124/dmd.108.022368
Li, Chun
- You have accessIn Vitro Metabolism of the Novel, Highly Selective Oral Angiogenesis Inhibitor Motesanib Diphosphate in Preclinical Species and in HumansChun Li, Mita Kuchimanchi, Dean Hickman, Leszek Poppe, Mike Hayashi, Yihong Zhou, Raju Subramanian, Gondi Kumar and Sekhar SurapaneniDrug Metabolism and Disposition July 2009, 37 (7) 1378-1394; DOI: https://doi.org/10.1124/dmd.108.025742
Li, Na
- You have accessEvaluation of in Vitro Models for Screening Alkaline Phosphatase-Mediated Bioconversion of Phosphate Ester ProdrugsHaodan Yuan, Na Li and Yurong LaiDrug Metabolism and Disposition July 2009, 37 (7) 1443-1447; DOI: https://doi.org/10.1124/dmd.108.026245
Lichti, Cheryl F.
- You have accessCharacterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic CannabinoidsAnna Mazur, Cheryl F. Lichti, Paul L. Prather, Agnieszka K. Zielinska, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska-Pandya and Jeffery H. MoranDrug Metabolism and Disposition July 2009, 37 (7) 1496-1504; DOI: https://doi.org/10.1124/dmd.109.026898
Lim, Heng-Keang
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Ling, Kah-Hiing John
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Liu, Xingrong
- You have accessUnbound Brain Concentration Determines Receptor Occupancy: A Correlation of Drug Concentration and Brain Serotonin and Dopamine Reuptake Transporter Occupancy for Eighteen Compounds in RatsXingrong Liu, Olga Vilenski, Joyce Kwan, Subbu Apparsundaram and Robert WeikertDrug Metabolism and Disposition July 2009, 37 (7) 1548-1556; DOI: https://doi.org/10.1124/dmd.109.026674
Löfgren, Susanne
- You have accessRegulation of Human CYP2C18 and CYP2C19 in Transgenic Mice: Influence of Castration, Testosterone, and Growth HormoneSusanne Löfgren, R. Michael Baldwin, Margareta Carlerös, Ylva Terelius, Ronny Fransson-Steen, Jessica Mwinyi, David J. Waxman and Magnus Ingelman-SundbergDrug Metabolism and Disposition July 2009, 37 (7) 1505-1512; DOI: https://doi.org/10.1124/dmd.109.026963
Loriot, Marie-Anne
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Lu, Chuang
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
M
Mackenzie, Peter I.
- You have accessCharacterization of the Binding of Drugs to Human Intestinal Fatty Acid Binding Protein (IFABP): Potential Role of IFABP as an Alternative to Albumin for in Vitro-in Vivo Extrapolation of Drug Kinetic ParametersAndrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. MinersDrug Metabolism and Disposition July 2009, 37 (7) 1395-1403; DOI: https://doi.org/10.1124/dmd.109.027656
Maeda, Kazuya
- You have accessPrediction of the Hepatic and Renal Clearance of Transporter Substrates in Rats Using in Vitro Uptake ExperimentsTomoko Watanabe, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition July 2009, 37 (7) 1471-1479; DOI: https://doi.org/10.1124/dmd.108.026062
Maeno, Kazuma
- You have accessMolecular Basis for Reduced Estrone Sulfate Transport and Altered Modulator Sensitivity of Transmembrane Helix (TM) 6 and TM17 Mutants of Multidrug Resistance Protein 1 (ABCC1)Kazuma Maeno, Akio Nakajima, Gwenaëlle Conseil, Alice Rothnie, Roger G. Deeley and Susan P. C. ColeDrug Metabolism and Disposition July 2009, 37 (7) 1411-1420; DOI: https://doi.org/10.1124/dmd.109.026633
Maruyama, Toru
- You have accessPharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen CarrierKazuaki Taguchi, Yukino Urata, Makoto Anraku, Toru Maruyama, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toshiya Kai and Masaki OtagiriDrug Metabolism and Disposition July 2009, 37 (7) 1456-1463; DOI: https://doi.org/10.1124/dmd.109.027094
Mazur, Anna
- You have accessCharacterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic CannabinoidsAnna Mazur, Cheryl F. Lichti, Paul L. Prather, Agnieszka K. Zielinska, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska-Pandya and Jeffery H. MoranDrug Metabolism and Disposition July 2009, 37 (7) 1496-1504; DOI: https://doi.org/10.1124/dmd.109.026898
Mellottée, Lucille
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Miller, Grover P.
- You have accessCharacterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic CannabinoidsAnna Mazur, Cheryl F. Lichti, Paul L. Prather, Agnieszka K. Zielinska, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska-Pandya and Jeffery H. MoranDrug Metabolism and Disposition July 2009, 37 (7) 1496-1504; DOI: https://doi.org/10.1124/dmd.109.026898
Miners, John O.
- You have accessCharacterization of the Binding of Drugs to Human Intestinal Fatty Acid Binding Protein (IFABP): Potential Role of IFABP as an Alternative to Albumin for in Vitro-in Vivo Extrapolation of Drug Kinetic ParametersAndrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. MinersDrug Metabolism and Disposition July 2009, 37 (7) 1395-1403; DOI: https://doi.org/10.1124/dmd.109.027656
Miwa, K.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Miya, T.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Mizuno, K.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Monks, Terrence J.
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Moore, David
- You have accessIn Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America PerspectiveValeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej SkerjanecDrug Metabolism and Disposition July 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029
Moran, Jeffery H.
- You have accessCharacterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic CannabinoidsAnna Mazur, Cheryl F. Lichti, Paul L. Prather, Agnieszka K. Zielinska, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska-Pandya and Jeffery H. MoranDrug Metabolism and Disposition July 2009, 37 (7) 1496-1504; DOI: https://doi.org/10.1124/dmd.109.026898
Morris, Marilyn E.
- You have accessThe Drug of Abuse γ-Hydroxybutyrate Is a Substrate for Sodium-Coupled Monocarboxylate Transporter (SMCT) 1 (SLC5A8): Characterization of SMCT-Mediated Uptake and InhibitionDapeng Cui and Marilyn E. MorrisDrug Metabolism and Disposition July 2009, 37 (7) 1404-1410; DOI: https://doi.org/10.1124/dmd.109.027169
Mwinyi, Jessica
- You have accessRegulation of Human CYP2C18 and CYP2C19 in Transgenic Mice: Influence of Castration, Testosterone, and Growth HormoneSusanne Löfgren, R. Michael Baldwin, Margareta Carlerös, Ylva Terelius, Ronny Fransson-Steen, Jessica Mwinyi, David J. Waxman and Magnus Ingelman-SundbergDrug Metabolism and Disposition July 2009, 37 (7) 1505-1512; DOI: https://doi.org/10.1124/dmd.109.026963
N
Nagashima, F.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Nakajima, Akio
- You have accessMolecular Basis for Reduced Estrone Sulfate Transport and Altered Modulator Sensitivity of Transmembrane Helix (TM) 6 and TM17 Mutants of Multidrug Resistance Protein 1 (ABCC1)Kazuma Maeno, Akio Nakajima, Gwenaëlle Conseil, Alice Rothnie, Roger G. Deeley and Susan P. C. ColeDrug Metabolism and Disposition July 2009, 37 (7) 1411-1420; DOI: https://doi.org/10.1124/dmd.109.026633
Nakajima, Miki
- You have accessHuman Arylacetamide Deacetylase Is a Principal Enzyme in Flutamide HydrolysisAkinobu Watanabe, Tatsuki Fukami, Miki Nakajima, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi YokoiDrug Metabolism and Disposition July 2009, 37 (7) 1513-1520; DOI: https://doi.org/10.1124/dmd.109.026567
Nakano, Takafumi
- You have accessCorrelation between Apical Localization of Abcc2/Mrp2 and Phosphorylation Status of Ezrin in Rat IntestineTakafumi Nakano, Shuichi Sekine, Kousei Ito and Toshiharu HorieDrug Metabolism and Disposition July 2009, 37 (7) 1521-1527; DOI: https://doi.org/10.1124/dmd.108.024836
Nakayama, H.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Nakayama, Hideki
- You have accessPrediction of the Hepatic and Renal Clearance of Transporter Substrates in Rats Using in Vitro Uptake ExperimentsTomoko Watanabe, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition July 2009, 37 (7) 1471-1479; DOI: https://doi.org/10.1124/dmd.108.026062
Narabayashi, M.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Noguchi, Kiyoshi
- You have accessRelationship between Exposure of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a “Funny” If Current Channel Inhibitor, and Heart Rate Reduction in Tachycardia-Induced Beagle DogsKen-ichi Umehara, Kouichi Wada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition July 2009, 37 (7) 1427-1433; DOI: https://doi.org/10.1124/dmd.108.026385
Nomeir, Amin A.
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
O
O'Connell, Thomas N.
- You have accessBiotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist in Sprague-Dawley Rats and the Dispositional Characterization of Its N-Carbamoyl Glucuronide MetaboliteChristopher L. Shaffer, Tim F. Ryder, Karthik Venkatakrishnan, Ilana K. Henne and Thomas N. O'ConnellDrug Metabolism and Disposition July 2009, 37 (7) 1480-1489; DOI: https://doi.org/10.1124/dmd.109.027037
O'Mathúna, Brian
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Obach, R. Scott
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Otagiri, Masaki
- You have accessPharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen CarrierKazuaki Taguchi, Yukino Urata, Makoto Anraku, Toru Maruyama, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toshiya Kai and Masaki OtagiriDrug Metabolism and Disposition July 2009, 37 (7) 1456-1463; DOI: https://doi.org/10.1124/dmd.109.027094
P
Park, Soo-Jin
- You have accessDiscovery of Novel Functional Variants and Extensive Evaluation of CYP2D6 Genetic Polymorphisms in KoreansSu-Jun Lee, Sang Seop Lee, Hyun-Ju Jung, Ho-Sook Kim, Soo-Jin Park, Chang-Woo Yeo and Jae-Gook ShinDrug Metabolism and Disposition July 2009, 37 (7) 1464-1470; DOI: https://doi.org/10.1124/dmd.108.022368
Pascual, Jose Antonio
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Pellegrini, Manuela
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Perfetti, Ximena
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Petzinger, Ernst
- You have accessThe Role of P-Glycoprotein in Limiting Brain Penetration of the Peripherally Acting Anticholinergic Overactive Bladder Drug Trospium ChlorideJoachim Geyer, Olga Gavrilova and Ernst PetzingerDrug Metabolism and Disposition July 2009, 37 (7) 1371-1374; DOI: https://doi.org/10.1124/dmd.109.027144
Pichini, Simona
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Pizarro, Nieves
- You have accessNeurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy IngestionXimena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la TorreDrug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Poppe, Leszek
- You have accessIn Vitro Metabolism of the Novel, Highly Selective Oral Angiogenesis Inhibitor Motesanib Diphosphate in Preclinical Species and in HumansChun Li, Mita Kuchimanchi, Dean Hickman, Leszek Poppe, Mike Hayashi, Yihong Zhou, Raju Subramanian, Gondi Kumar and Sekhar SurapaneniDrug Metabolism and Disposition July 2009, 37 (7) 1378-1394; DOI: https://doi.org/10.1124/dmd.108.025742
Prather, Paul L.
- You have accessCharacterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic CannabinoidsAnna Mazur, Cheryl F. Lichti, Paul L. Prather, Agnieszka K. Zielinska, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska-Pandya and Jeffery H. MoranDrug Metabolism and Disposition July 2009, 37 (7) 1496-1504; DOI: https://doi.org/10.1124/dmd.109.026898
R
Radomińska-Pandya, Anna
- You have accessCharacterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic CannabinoidsAnna Mazur, Cheryl F. Lichti, Paul L. Prather, Agnieszka K. Zielinska, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska-Pandya and Jeffery H. MoranDrug Metabolism and Disposition July 2009, 37 (7) 1496-1504; DOI: https://doi.org/10.1124/dmd.109.026898
Ripp, Sharon
- You have accessIn Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America PerspectiveValeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej SkerjanecDrug Metabolism and Disposition July 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029
Rothnie, Alice
- You have accessMolecular Basis for Reduced Estrone Sulfate Transport and Altered Modulator Sensitivity of Transmembrane Helix (TM) 6 and TM17 Mutants of Multidrug Resistance Protein 1 (ABCC1)Kazuma Maeno, Akio Nakajima, Gwenaëlle Conseil, Alice Rothnie, Roger G. Deeley and Susan P. C. ColeDrug Metabolism and Disposition July 2009, 37 (7) 1411-1420; DOI: https://doi.org/10.1124/dmd.109.026633
Rowland, Andrew
- You have accessCharacterization of the Binding of Drugs to Human Intestinal Fatty Acid Binding Protein (IFABP): Potential Role of IFABP as an Alternative to Albumin for in Vitro-in Vivo Extrapolation of Drug Kinetic ParametersAndrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. MinersDrug Metabolism and Disposition July 2009, 37 (7) 1395-1403; DOI: https://doi.org/10.1124/dmd.109.027656
Ryder, Tim F.
- You have accessBiotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist in Sprague-Dawley Rats and the Dispositional Characterization of Its N-Carbamoyl Glucuronide MetaboliteChristopher L. Shaffer, Tim F. Ryder, Karthik Venkatakrishnan, Ilana K. Henne and Thomas N. O'ConnellDrug Metabolism and Disposition July 2009, 37 (7) 1480-1489; DOI: https://doi.org/10.1124/dmd.109.027037
S
Sahagún, Ana
- You have accessEffects of Plantago ovata Husk on Levodopa (with Carbidopa) Bioavailability in Rabbits with Autonomic Gastrointestinal DisordersJuan J. García, Nélida Fernández, Ángela P. Calle, M. José Diez, Ana Sahagún and Matilde SierraDrug Metabolism and Disposition July 2009, 37 (7) 1434-1442; DOI: https://doi.org/10.1124/dmd.108.026229
Sakai, Hiromi
- You have accessPharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen CarrierKazuaki Taguchi, Yukino Urata, Makoto Anraku, Toru Maruyama, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toshiya Kai and Masaki OtagiriDrug Metabolism and Disposition July 2009, 37 (7) 1456-1463; DOI: https://doi.org/10.1124/dmd.109.027094
Sasaki, Y.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Sazdovitch, Véronique
- You have accessXenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral FunctionFabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers, Philippe Beaune, Xavier Declèves, Charles Duyckaerts and Marie-Anne LoriotDrug Metabolism and Disposition July 2009, 37 (7) 1528-1538; DOI: https://doi.org/10.1124/dmd.109.027011
Schneider, Joachim
- You have accessInfluence of the Cyp1B1 L432V Gene Polymorphism and Exposure to Tobacco Smoke on Cyp1B1 mRNA Expression in Human LeukocytesSimone Helmig, Bahar Hadzaad, Juliane Döhrel and Joachim SchneiderDrug Metabolism and Disposition July 2009, 37 (7) 1490-1495; DOI: https://doi.org/10.1124/dmd.109.027060
Seibert, Eleanore
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Sekine, Shuichi
- You have accessCorrelation between Apical Localization of Abcc2/Mrp2 and Phosphorylation Status of Ezrin in Rat IntestineTakafumi Nakano, Shuichi Sekine, Kousei Ito and Toshiharu HorieDrug Metabolism and Disposition July 2009, 37 (7) 1521-1527; DOI: https://doi.org/10.1124/dmd.108.024836
Shaffer, Christopher L.
- You have accessBiotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist in Sprague-Dawley Rats and the Dispositional Characterization of Its N-Carbamoyl Glucuronide MetaboliteChristopher L. Shaffer, Tim F. Ryder, Karthik Venkatakrishnan, Ilana K. Henne and Thomas N. O'ConnellDrug Metabolism and Disposition July 2009, 37 (7) 1480-1489; DOI: https://doi.org/10.1124/dmd.109.027037
Shin, Jae-Gook
- You have accessDiscovery of Novel Functional Variants and Extensive Evaluation of CYP2D6 Genetic Polymorphisms in KoreansSu-Jun Lee, Sang Seop Lee, Hyun-Ju Jung, Ho-Sook Kim, Soo-Jin Park, Chang-Woo Yeo and Jae-Gook ShinDrug Metabolism and Disposition July 2009, 37 (7) 1464-1470; DOI: https://doi.org/10.1124/dmd.108.022368
Sierra, Matilde
- You have accessEffects of Plantago ovata Husk on Levodopa (with Carbidopa) Bioavailability in Rabbits with Autonomic Gastrointestinal DisordersJuan J. García, Nélida Fernández, Ángela P. Calle, M. José Diez, Ana Sahagún and Matilde SierraDrug Metabolism and Disposition July 2009, 37 (7) 1434-1442; DOI: https://doi.org/10.1124/dmd.108.026229
Silva, Jose
- You have accessIn Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America PerspectiveValeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej SkerjanecDrug Metabolism and Disposition July 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029
Sinha, Vikram
- You have accessIn Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America PerspectiveValeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej SkerjanecDrug Metabolism and Disposition July 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029
Sinz, Michael
- You have accessIn Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America PerspectiveValeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej SkerjanecDrug Metabolism and Disposition July 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029
Skerjanec, Andrej
- You have accessIn Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America PerspectiveValeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej SkerjanecDrug Metabolism and Disposition July 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029
Skordos, Konstantine W.
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Staudinger, Jeff L.
- You have accessRegulation of Tissue-Specific Carboxylesterase Expression by Pregnane X Receptor and Constitutive Androstane ReceptorChenshu Xu, Xinkun Wang and Jeff L. StaudingerDrug Metabolism and Disposition July 2009, 37 (7) 1539-1547; DOI: https://doi.org/10.1124/dmd.109.026989
Subramanian, Raju
- You have accessIn Vitro Metabolism of the Novel, Highly Selective Oral Angiogenesis Inhibitor Motesanib Diphosphate in Preclinical Species and in HumansChun Li, Mita Kuchimanchi, Dean Hickman, Leszek Poppe, Mike Hayashi, Yihong Zhou, Raju Subramanian, Gondi Kumar and Sekhar SurapaneniDrug Metabolism and Disposition July 2009, 37 (7) 1378-1394; DOI: https://doi.org/10.1124/dmd.108.025742
Sugiyama, Yuichi
- You have accessPrediction of the Hepatic and Renal Clearance of Transporter Substrates in Rats Using in Vitro Uptake ExperimentsTomoko Watanabe, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition July 2009, 37 (7) 1471-1479; DOI: https://doi.org/10.1124/dmd.108.026062
Sunakawa, Y.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Surapaneni, Sekhar
- You have accessIn Vitro Metabolism of the Novel, Highly Selective Oral Angiogenesis Inhibitor Motesanib Diphosphate in Preclinical Species and in HumansChun Li, Mita Kuchimanchi, Dean Hickman, Leszek Poppe, Mike Hayashi, Yihong Zhou, Raju Subramanian, Gondi Kumar and Sekhar SurapaneniDrug Metabolism and Disposition July 2009, 37 (7) 1378-1394; DOI: https://doi.org/10.1124/dmd.108.025742
T
Taguchi, Kazuaki
- You have accessPharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen CarrierKazuaki Taguchi, Yukino Urata, Makoto Anraku, Toru Maruyama, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toshiya Kai and Masaki OtagiriDrug Metabolism and Disposition July 2009, 37 (7) 1456-1463; DOI: https://doi.org/10.1124/dmd.109.027094
Takamiya, Masataka
- You have accessHuman Arylacetamide Deacetylase Is a Principal Enzyme in Flutamide HydrolysisAkinobu Watanabe, Tatsuki Fukami, Miki Nakajima, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi YokoiDrug Metabolism and Disposition July 2009, 37 (7) 1513-1520; DOI: https://doi.org/10.1124/dmd.109.026567
Tanaka, R.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Terelius, Ylva
- You have accessRegulation of Human CYP2C18 and CYP2C19 in Transgenic Mice: Influence of Castration, Testosterone, and Growth HormoneSusanne Löfgren, R. Michael Baldwin, Margareta Carlerös, Ylva Terelius, Ronny Fransson-Steen, Jessica Mwinyi, David J. Waxman and Magnus Ingelman-SundbergDrug Metabolism and Disposition July 2009, 37 (7) 1505-1512; DOI: https://doi.org/10.1124/dmd.109.026963
Tonn, George R.
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Tsuchida, Eishun
- You have accessPharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen CarrierKazuaki Taguchi, Yukino Urata, Makoto Anraku, Toru Maruyama, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toshiya Kai and Masaki OtagiriDrug Metabolism and Disposition July 2009, 37 (7) 1456-1463; DOI: https://doi.org/10.1124/dmd.109.027094
U
Umehara, Ken-ichi
- You have accessRelationship between Exposure of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a “Funny” If Current Channel Inhibitor, and Heart Rate Reduction in Tachycardia-Induced Beagle DogsKen-ichi Umehara, Kouichi Wada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition July 2009, 37 (7) 1427-1433; DOI: https://doi.org/10.1124/dmd.108.026385
Urata, Yukino
- You have accessPharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen CarrierKazuaki Taguchi, Yukino Urata, Makoto Anraku, Toru Maruyama, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toshiya Kai and Masaki OtagiriDrug Metabolism and Disposition July 2009, 37 (7) 1456-1463; DOI: https://doi.org/10.1124/dmd.109.027094
Usui, Takashi
- You have accessRelationship between Exposure of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a “Funny” If Current Channel Inhibitor, and Heart Rate Reduction in Tachycardia-Induced Beagle DogsKen-ichi Umehara, Kouichi Wada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition July 2009, 37 (7) 1427-1433; DOI: https://doi.org/10.1124/dmd.108.026385
V
Van Horn, Robert
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Venkatakrishnan, Karthik
- You have accessBiotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist in Sprague-Dawley Rats and the Dispositional Characterization of Its N-Carbamoyl Glucuronide MetaboliteChristopher L. Shaffer, Tim F. Ryder, Karthik Venkatakrishnan, Ilana K. Henne and Thomas N. O'ConnellDrug Metabolism and Disposition July 2009, 37 (7) 1480-1489; DOI: https://doi.org/10.1124/dmd.109.027037
Vilenski, Olga
- You have accessUnbound Brain Concentration Determines Receptor Occupancy: A Correlation of Drug Concentration and Brain Serotonin and Dopamine Reuptake Transporter Occupancy for Eighteen Compounds in RatsXingrong Liu, Olga Vilenski, Joyce Kwan, Subbu Apparsundaram and Robert WeikertDrug Metabolism and Disposition July 2009, 37 (7) 1548-1556; DOI: https://doi.org/10.1124/dmd.109.026674
W
Wada, Kouichi
- You have accessRelationship between Exposure of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a “Funny” If Current Channel Inhibitor, and Heart Rate Reduction in Tachycardia-Induced Beagle DogsKen-ichi Umehara, Kouichi Wada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition July 2009, 37 (7) 1427-1433; DOI: https://doi.org/10.1124/dmd.108.026385
Wang, Regina W.
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Wang, Xinkun
- You have accessRegulation of Tissue-Specific Carboxylesterase Expression by Pregnane X Receptor and Constitutive Androstane ReceptorChenshu Xu, Xinkun Wang and Jeff L. StaudingerDrug Metabolism and Disposition July 2009, 37 (7) 1539-1547; DOI: https://doi.org/10.1124/dmd.109.026989
Watanabe, Akinobu
- You have accessHuman Arylacetamide Deacetylase Is a Principal Enzyme in Flutamide HydrolysisAkinobu Watanabe, Tatsuki Fukami, Miki Nakajima, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi YokoiDrug Metabolism and Disposition July 2009, 37 (7) 1513-1520; DOI: https://doi.org/10.1124/dmd.109.026567
Watanabe, Hiroshi
- You have accessPharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen CarrierKazuaki Taguchi, Yukino Urata, Makoto Anraku, Toru Maruyama, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toshiya Kai and Masaki OtagiriDrug Metabolism and Disposition July 2009, 37 (7) 1456-1463; DOI: https://doi.org/10.1124/dmd.109.027094
Watanabe, Tomoko
- You have accessPrediction of the Hepatic and Renal Clearance of Transporter Substrates in Rats Using in Vitro Uptake ExperimentsTomoko Watanabe, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition July 2009, 37 (7) 1471-1479; DOI: https://doi.org/10.1124/dmd.108.026062
Waxman, David J.
- You have accessRegulation of Human CYP2C18 and CYP2C19 in Transgenic Mice: Influence of Castration, Testosterone, and Growth HormoneSusanne Löfgren, R. Michael Baldwin, Margareta Carlerös, Ylva Terelius, Ronny Fransson-Steen, Jessica Mwinyi, David J. Waxman and Magnus Ingelman-SundbergDrug Metabolism and Disposition July 2009, 37 (7) 1505-1512; DOI: https://doi.org/10.1124/dmd.109.026963
Weber, Benjamin
- You have accessBudesonide and Ciclesonide: Effect of Tissue Binding on Pulmonary Receptor BindingKai Wu, Anders L. Blomgren, Kjell Ekholm, Benjamin Weber, Staffan Edsbaecker and Günther HochhausDrug Metabolism and Disposition July 2009, 37 (7) 1421-1426; DOI: https://doi.org/10.1124/dmd.108.026039
Weikert, Robert
- You have accessUnbound Brain Concentration Determines Receptor Occupancy: A Correlation of Drug Concentration and Brain Serotonin and Dopamine Reuptake Transporter Occupancy for Eighteen Compounds in RatsXingrong Liu, Olga Vilenski, Joyce Kwan, Subbu Apparsundaram and Robert WeikertDrug Metabolism and Disposition July 2009, 37 (7) 1548-1556; DOI: https://doi.org/10.1124/dmd.109.026674
Wen, Bo
- You have accessMetabolic Activation of Nevirapine in Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4Bo Wen, Yuan Chen and William L. FitchDrug Metabolism and Disposition July 2009, 37 (7) 1557-1562; DOI: https://doi.org/10.1124/dmd.108.024851
Wong, Y. Nancy
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Wu, Kai
- You have accessBudesonide and Ciclesonide: Effect of Tissue Binding on Pulmonary Receptor BindingKai Wu, Anders L. Blomgren, Kjell Ekholm, Benjamin Weber, Staffan Edsbaecker and Günther HochhausDrug Metabolism and Disposition July 2009, 37 (7) 1421-1426; DOI: https://doi.org/10.1124/dmd.108.026039
X
Xu, Chenshu
- You have accessRegulation of Tissue-Specific Carboxylesterase Expression by Pregnane X Receptor and Constitutive Androstane ReceptorChenshu Xu, Xinkun Wang and Jeff L. StaudingerDrug Metabolism and Disposition July 2009, 37 (7) 1539-1547; DOI: https://doi.org/10.1124/dmd.109.026989
Y
Yamamoto, W.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Yamashita, K.
- You have accessPharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine)K. Fujita, H. Nakayama, W. Ichikawa, W. Yamamoto, H. Endo, F. Nagashima, R. Tanaka, T. Miya, Y. Sunakawa, K. Yamashita, K. Mizuno, H. Ishida, K. Araki, M. Narabayashi, K. Miwa, Y. Ando, Y. Akiyama, K. Kawara, T. Hirose and Y. SasakiDrug Metabolism and Disposition July 2009, 37 (7) 1375-1377; DOI: https://doi.org/10.1124/dmd.109.027052
Yang, Tian J.
- You have accessThe Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of AmericaScott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott ObachDrug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716
Yeo, Chang-Woo
- You have accessDiscovery of Novel Functional Variants and Extensive Evaluation of CYP2D6 Genetic Polymorphisms in KoreansSu-Jun Lee, Sang Seop Lee, Hyun-Ju Jung, Ho-Sook Kim, Soo-Jin Park, Chang-Woo Yeo and Jae-Gook ShinDrug Metabolism and Disposition July 2009, 37 (7) 1464-1470; DOI: https://doi.org/10.1124/dmd.108.022368
Yokoi, Tsuyoshi
- You have accessHuman Arylacetamide Deacetylase Is a Principal Enzyme in Flutamide HydrolysisAkinobu Watanabe, Tatsuki Fukami, Miki Nakajima, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi YokoiDrug Metabolism and Disposition July 2009, 37 (7) 1513-1520; DOI: https://doi.org/10.1124/dmd.109.026567
Yuan, Haodan
- You have accessEvaluation of in Vitro Models for Screening Alkaline Phosphatase-Mediated Bioconversion of Phosphate Ester ProdrugsHaodan Yuan, Na Li and Yurong LaiDrug Metabolism and Disposition July 2009, 37 (7) 1443-1447; DOI: https://doi.org/10.1124/dmd.108.026245
Z
Zhou, Yihong
- You have accessIn Vitro Metabolism of the Novel, Highly Selective Oral Angiogenesis Inhibitor Motesanib Diphosphate in Preclinical Species and in HumansChun Li, Mita Kuchimanchi, Dean Hickman, Leszek Poppe, Mike Hayashi, Yihong Zhou, Raju Subramanian, Gondi Kumar and Sekhar SurapaneniDrug Metabolism and Disposition July 2009, 37 (7) 1378-1394; DOI: https://doi.org/10.1124/dmd.108.025742
Zielinska, Agnieszka K.
- You have accessCharacterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic CannabinoidsAnna Mazur, Cheryl F. Lichti, Paul L. Prather, Agnieszka K. Zielinska, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska-Pandya and Jeffery H. MoranDrug Metabolism and Disposition July 2009, 37 (7) 1496-1504; DOI: https://doi.org/10.1124/dmd.109.026898
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