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Research ArticlePerspective

In Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America Perspective

Valeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej Skerjanec
Drug Metabolism and Disposition July 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029

Article Information

vol. 37 no. 7 1339-1354
DOI 
https://doi.org/10.1124/dmd.109.027029
PubMed 
19389860
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Accepted April 17, 2009
  • Received February 2, 2009
  • Published online June 18, 2009.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Valeria Chu,
  2. Heidi J. Einolf,
  3. Raymond Evers,
  4. Gondi Kumar,
  5. David Moore,
  6. Sharon Ripp,
  7. Jose Silva,
  8. Vikram Sinha,
  9. Michael Sinz and
  10. Andrej Skerjanec
  1. Sanofi-aventis United States, Bridgewater, New Jersey (V.C.); Novartis Pharmaceuticals Corporation, East Hanover, New Jersey (H.J.E.); Novartis Pharmaceuticals Corporation, Florham Park, New Jersey (A.S.); Merck & Co., Inc., Rahway, New Jersey (R.E.); Celgene Corporation, Summit, New Jersey (G.K.); Roche, Nutley, New Jersey (D.M.); Pfizer Global Research and Development, Groton, Connecticut (S.R.); Johnson & Johnson, Raritan, New Jersey (J.S.); Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (V.S.); and Bristol-Myers Squibb, Wallingford, Connecticut (M.S.)
  1. Address correspondence to:
    Gondi Kumar, Celgene Corporation, 86 Morris Avenue, Summit, NJ 07901. E-mail: gkumar{at}celgene.com
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Research ArticlePerspective

In Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America Perspective

Valeria Chu, Heidi J. Einolf, Raymond Evers, Gondi Kumar, David Moore, Sharon Ripp, Jose Silva, Vikram Sinha, Michael Sinz and Andrej Skerjanec
Drug Metabolism and Disposition July 1, 2009, 37 (7) 1339-1354; DOI: https://doi.org/10.1124/dmd.109.027029
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