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Research ArticleArticle

Neurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy Ingestion

Ximena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la Torre
Drug Metabolism and Disposition July 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
Ximena Perfetti
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Brian O'Mathúna
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Nieves Pizarro
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Elisabet Cuyàs
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Olha Khymenets
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Bruno Almeida
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Manuela Pellegrini
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Simona Pichini
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Serrine S. Lau
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Terrence J. Monks
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Magí Farré
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Jose Antonio Pascual
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Jesús Joglar
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Rafael de la Torre
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Article Information

vol. 37 no. 7 1448-1455
DOI 
https://doi.org/10.1124/dmd.108.026393
PubMed 
19349378

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Accepted April 2, 2009
  • Received January 7, 2009
  • Published online June 18, 2009.

Article Versions

  • Earlier version (April 6, 2009 - 07:21).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Ximena Perfetti,
  2. Brian O'Mathúna,
  3. Nieves Pizarro,
  4. Elisabet Cuyàs,
  5. Olha Khymenets,
  6. Bruno Almeida,
  7. Manuela Pellegrini,
  8. Simona Pichini,
  9. Serrine S. Lau,
  10. Terrence J. Monks,
  11. Magí Farré,
  12. Jose Antonio Pascual,
  13. Jesús Joglar and
  14. Rafael de la Torre
  1. Human Pharmacology and Clinical Neurosciences Research Group (X.P., B.O., N.P., E.C., O.K., B.A., M.F., R.d.T.) and Bioanalysis and Analytical Services Research Group (J.A.P.), Institut Municipal d'Investigació Mèdica-Hospital del Mar, Barcelona, Spain; Universitat Pompeu Fabra, Barcelona, Spain (X.P., B.O., O.K., B.A., R.T.); Research Unit on Biotransformations and BioActive Molecules, Catalonia Institute for Advanced Chemistry, Spanish Council for Scientific Research, Barcelona, Spain (B.A., J.J.); Universidad Autónoma de Barcelona, Barcelona, Spain (E.C., M.F.); Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona Health Sciences Center, Tucson, Arizona (S.S.L., T.J.M.); and Department of Therapeutic Research and Medicines Evaluation, Instituto Superiore di Sanita, Rome, Italy (M.P., S.P.)
  1. Address correspondence to:
    Dr. Rafael de la Torre, Institut Municipal d'Investigació Mèdica-Hospital del Mar, Dr. Aiguader 88, Barcelona, Spain, 08003. E-mail: rtorre{at}imim.es
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Drug Metabolism and Disposition: 37 (7)
Drug Metabolism and Disposition
Vol. 37, Issue 7
1 Jul 2009
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Research ArticleArticle

Neurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy Ingestion

Ximena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la Torre
Drug Metabolism and Disposition July 1, 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393

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Research ArticleArticle

Neurotoxic Thioether Adducts of 3,4-Methylenedioxymethamphetamine Identified in Human Urine After Ecstasy Ingestion

Ximena Perfetti, Brian O'Mathúna, Nieves Pizarro, Elisabet Cuyàs, Olha Khymenets, Bruno Almeida, Manuela Pellegrini, Simona Pichini, Serrine S. Lau, Terrence J. Monks, Magí Farré, Jose Antonio Pascual, Jesús Joglar and Rafael de la Torre
Drug Metabolism and Disposition July 1, 2009, 37 (7) 1448-1455; DOI: https://doi.org/10.1124/dmd.108.026393
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