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Research ArticleArticle

Prediction of the Hepatic and Renal Clearance of Transporter Substrates in Rats Using in Vitro Uptake Experiments

Tomoko Watanabe, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
Drug Metabolism and Disposition July 2009, 37 (7) 1471-1479; DOI: https://doi.org/10.1124/dmd.108.026062

Article Information

vol. 37 no. 7 1471-1479
DOI 
https://doi.org/10.1124/dmd.108.026062
PubMed 
19364828
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Accepted April 9, 2009
  • Received December 8, 2008
  • Published online June 18, 2009.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Tomoko Watanabe,
  2. Kazuya Maeda,
  3. Tsunenori Kondo,
  4. Hideki Nakayama,
  5. Shigeru Horita,
  6. Hiroyuki Kusuhara and
  7. Yuichi Sugiyama
  1. Department of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo, Japan (T.W., K.M., H.K., Y.S.); and Department of Urology, Kidney Center, Tokyo Women's Medical University, Tokyo, Japan (T.K., H.N., S.H.)
  1. Address correspondence to:
    Dr. Yuichi Sugiyama, Department of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. E-mail: sugiyama{at}mol.f.u-tokyo.ac.jp
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Research ArticleArticle

Prediction of the Hepatic and Renal Clearance of Transporter Substrates in Rats Using in Vitro Uptake Experiments

Tomoko Watanabe, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara and Yuichi Sugiyama
Drug Metabolism and Disposition July 1, 2009, 37 (7) 1471-1479; DOI: https://doi.org/10.1124/dmd.108.026062
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