Index by author
September 01, 2009; Volume 37,Issue 9
A
Abe, Koji
- You have accessSex-Dependent Disposition of Acetaminophen Sulfate and Glucuronide in the in Situ Perfused Mouse LiverJin Kyung Lee, Koji Abe, Arlene S. Bridges, Nita J. Patel, Thomas J. Raub, Gary M. Pollack and Kim L. R. BrouwerDrug Metabolism and Disposition September 2009, 37 (9) 1916-1921; DOI: https://doi.org/10.1124/dmd.109.026815
Appel, David I.
- You have accessAge- and Sex-Related Expression and Activity of Carboxylesterase 1 and 2 in Mouse and Human LiverHao-Jie Zhu, David I. Appel, Yan Jiang and John S. MarkowitzDrug Metabolism and Disposition September 2009, 37 (9) 1819-1825; DOI: https://doi.org/10.1124/dmd.109.028209
Atsumi, Ryo
- You have accessMetabolism of Ticlopidine in Rats: Identification of the Main Biliary Metabolite as a Glutathione Conjugate of Ticlopidine S-OxideShinji Shimizu, Ryo Atsumi, Tsunenori Nakazawa, Yuko Fujimaki, Kenichi Sudo and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1904-1915; DOI: https://doi.org/10.1124/dmd.109.027524
- You have accessA Zone Classification System for Risk Assessment of Idiosyncratic Drug Toxicity Using Daily Dose and Covalent BindingShintaro Nakayama, Ryo Atsumi, Hideo Takakusa, Yoshimasa Kobayashi, Atsushi Kurihara, Yoko Nagai, Daisuke Nakai and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1970-1977; DOI: https://doi.org/10.1124/dmd.109.027797
B
Bandiera, Stelvio M.
- You have access3-Ketocholanoic Acid Is the Major in Vitro Human Hepatic Microsomal Metabolite of Lithocholic AcidAnand K. Deo and Stelvio M. BandieraDrug Metabolism and Disposition September 2009, 37 (9) 1938-1947; DOI: https://doi.org/10.1124/dmd.109.027763
Beaumont, Kevin
- You have accessModulation of the Partition Coefficient between Octanol and Buffer at pH 7.4 and pKa to Achieve the Optimum Balance of Blood Clearance and Volume of Distribution for a Series of Tetrahydropyran Histamine Type 3 Receptor AntagonistsTanya Hay, Rhys Jones, Kevin Beaumont and Mark KempDrug Metabolism and Disposition September 2009, 37 (9) 1864-1870; DOI: https://doi.org/10.1124/dmd.109.027888
Beglinger, Christoph
- You have accessChanges in mRNA Expression Levels of Solute Carrier Transporters in Inflammatory Bowel Disease PatientsKacper A. Wojtal, Jyrki J. Eloranta, Petr Hruz, Heike Gutmann, Jürgen Drewe, Alex Staumann, Christoph Beglinger, Michael Fried, Gerd A. Kullak-Ublick and Stephan R. VavrickaDrug Metabolism and Disposition September 2009, 37 (9) 1871-1877; DOI: https://doi.org/10.1124/dmd.109.027367
Beijnen, J. H.
- You have accessIdentification and Profiling of Circulating Metabolites of Atazanavir, a HIV Protease InhibitorR. ter Heine, M. J. X. Hillebrand, H. Rosing, E. C. M. van Gorp, J. W. Mulder, J. H. Beijnen and A. D. R. HuitemaDrug Metabolism and Disposition September 2009, 37 (9) 1826-1840; DOI: https://doi.org/10.1124/dmd.109.028258
Bélanger, Anne-Sophie
- You have accessGlucuronidation of the Antiretroviral Drug Efavirenz by UGT2B7 and an in Vitro Investigation of Drug-Drug Interaction with ZidovudineAnne-Sophie Bélanger, Patrick Caron, Mario Harvey, Peter A. Zimmerman, Rajeev K. Mehlotra and Chantal GuillemetteDrug Metabolism and Disposition September 2009, 37 (9) 1793-1796; DOI: https://doi.org/10.1124/dmd.109.027706
Bowalgaha, Kushari
- You have accessInfluence of N-Terminal Domain Histidine and Proline Residues on the Substrate Selectivities of Human UDP-Glucuronosyltransferase 1A1, 1A6, 1A9, 2B7, and 2B10Oranun Kerdpin, Peter I. Mackenzie, Kushari Bowalgaha, Moshe Finel and John O. MinersDrug Metabolism and Disposition September 2009, 37 (9) 1948-1955; DOI: https://doi.org/10.1124/dmd.109.028225
Bridges, Arlene S.
- You have accessSex-Dependent Disposition of Acetaminophen Sulfate and Glucuronide in the in Situ Perfused Mouse LiverJin Kyung Lee, Koji Abe, Arlene S. Bridges, Nita J. Patel, Thomas J. Raub, Gary M. Pollack and Kim L. R. BrouwerDrug Metabolism and Disposition September 2009, 37 (9) 1916-1921; DOI: https://doi.org/10.1124/dmd.109.026815
Brobst, Dan
- You have accessAn in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 EnzymesAlaa-Eldin F. Nassar, Ivan King, Brandy L. Paris, Lois Haupt, Florence Ndikum-Moffor, Rebecca Campbell, Etsuko Usuki, Jennifer Skibbe, Dan Brobst, Brian W. Ogilvie and Andrew ParkinsonDrug Metabolism and Disposition September 2009, 37 (9) 1922-1930; DOI: https://doi.org/10.1124/dmd.109.027516
Brouwer, Kim L. R.
- You have accessSex-Dependent Disposition of Acetaminophen Sulfate and Glucuronide in the in Situ Perfused Mouse LiverJin Kyung Lee, Koji Abe, Arlene S. Bridges, Nita J. Patel, Thomas J. Raub, Gary M. Pollack and Kim L. R. BrouwerDrug Metabolism and Disposition September 2009, 37 (9) 1916-1921; DOI: https://doi.org/10.1124/dmd.109.026815
Brown, Cather
- You have accessContrasting Influence of NADPH and a NADPH-Regenerating System on the Metabolism of Carbonyl-Containing Compounds in Hepatic MicrosomesChristopher S. Mazur, John F. Kenneke, Michael-Rock Goldsmith and Cather BrownDrug Metabolism and Disposition September 2009, 37 (9) 1801-1805; DOI: https://doi.org/10.1124/dmd.109.027615
Buckley, David
- You have accessGenetic Polymorphisms in the TATA Box and Upstream Phenobarbital-Responsive Enhancer Module of the UGT1A1 Promoter Have Combined Effects on UDP-Glucuronosyltransferase 1A1 Transcription Mediated by Constitutive Androstane Receptor, Pregnane X Receptor, or Glucocorticoid Receptor in Human LiverYe Li, David Buckley, Shuang Wang, Curtis D. Klaassen and Xiao-bo ZhongDrug Metabolism and Disposition September 2009, 37 (9) 1978-1986; DOI: https://doi.org/10.1124/dmd.109.027409
C
Campbell, Rebecca
- You have accessAn in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 EnzymesAlaa-Eldin F. Nassar, Ivan King, Brandy L. Paris, Lois Haupt, Florence Ndikum-Moffor, Rebecca Campbell, Etsuko Usuki, Jennifer Skibbe, Dan Brobst, Brian W. Ogilvie and Andrew ParkinsonDrug Metabolism and Disposition September 2009, 37 (9) 1922-1930; DOI: https://doi.org/10.1124/dmd.109.027516
Caron, Patrick
- You have accessGlucuronidation of the Antiretroviral Drug Efavirenz by UGT2B7 and an in Vitro Investigation of Drug-Drug Interaction with ZidovudineAnne-Sophie Bélanger, Patrick Caron, Mario Harvey, Peter A. Zimmerman, Rajeev K. Mehlotra and Chantal GuillemetteDrug Metabolism and Disposition September 2009, 37 (9) 1793-1796; DOI: https://doi.org/10.1124/dmd.109.027706
Chang, Thomas K. H.
- You have accessInhibition of Human CYP2B6-Catalyzed Bupropion Hydroxylation by Ginkgo biloba Extract: Effect of Terpene Trilactones and FlavonolsAik Jiang Lau and Thomas K. H. ChangDrug Metabolism and Disposition September 2009, 37 (9) 1931-1937; DOI: https://doi.org/10.1124/dmd.109.028118
Chen, Huiqing
- You have accessUp-Regulation of UDP-Glucuronosyltransferase (UGT) 1A4 by 17β-Estradiol: A Potential Mechanism of Increased Lamotrigine Elimination in PregnancyHuiqing Chen, Kyunghee Yang, Suyoung Choi, James H. Fischer and Hyunyoung JeongDrug Metabolism and Disposition September 2009, 37 (9) 1841-1847; DOI: https://doi.org/10.1124/dmd.109.026609
Chiba, Masato
- You have accessAromatic Substitution Reaction of 2-Chloropyridines Catalyzed by Microsomal Glutathione S-Transferase 1Kazuko Inoue, Tomoyuki Ohe, Kenichi Mori, Takeshi Sagara, Yasuyuki Ishii and Masato ChibaDrug Metabolism and Disposition September 2009, 37 (9) 1797-1800; DOI: https://doi.org/10.1124/dmd.109.027698
Choi, Suyoung
- You have accessUp-Regulation of UDP-Glucuronosyltransferase (UGT) 1A4 by 17β-Estradiol: A Potential Mechanism of Increased Lamotrigine Elimination in PregnancyHuiqing Chen, Kyunghee Yang, Suyoung Choi, James H. Fischer and Hyunyoung JeongDrug Metabolism and Disposition September 2009, 37 (9) 1841-1847; DOI: https://doi.org/10.1124/dmd.109.026609
D
Deo, Anand K.
- You have access3-Ketocholanoic Acid Is the Major in Vitro Human Hepatic Microsomal Metabolite of Lithocholic AcidAnand K. Deo and Stelvio M. BandieraDrug Metabolism and Disposition September 2009, 37 (9) 1938-1947; DOI: https://doi.org/10.1124/dmd.109.027763
Drewe, Jürgen
- You have accessChanges in mRNA Expression Levels of Solute Carrier Transporters in Inflammatory Bowel Disease PatientsKacper A. Wojtal, Jyrki J. Eloranta, Petr Hruz, Heike Gutmann, Jürgen Drewe, Alex Staumann, Christoph Beglinger, Michael Fried, Gerd A. Kullak-Ublick and Stephan R. VavrickaDrug Metabolism and Disposition September 2009, 37 (9) 1871-1877; DOI: https://doi.org/10.1124/dmd.109.027367
E
Eddington, Natalie D.
- You have accessMethadone Induces the Expression of Hepatic Drug-Metabolizing Enzymes through the Activation of Pregnane X Receptor and Constitutive Androstane ReceptorAntonia H. Tolson, Haishan Li, Natalie D. Eddington and Hongbing WangDrug Metabolism and Disposition September 2009, 37 (9) 1887-1894; DOI: https://doi.org/10.1124/dmd.109.027854
Eloranta, Jyrki J.
- You have accessChanges in mRNA Expression Levels of Solute Carrier Transporters in Inflammatory Bowel Disease PatientsKacper A. Wojtal, Jyrki J. Eloranta, Petr Hruz, Heike Gutmann, Jürgen Drewe, Alex Staumann, Christoph Beglinger, Michael Fried, Gerd A. Kullak-Ublick and Stephan R. VavrickaDrug Metabolism and Disposition September 2009, 37 (9) 1871-1877; DOI: https://doi.org/10.1124/dmd.109.027367
F
Finel, Moshe
- You have accessInfluence of N-Terminal Domain Histidine and Proline Residues on the Substrate Selectivities of Human UDP-Glucuronosyltransferase 1A1, 1A6, 1A9, 2B7, and 2B10Oranun Kerdpin, Peter I. Mackenzie, Kushari Bowalgaha, Moshe Finel and John O. MinersDrug Metabolism and Disposition September 2009, 37 (9) 1948-1955; DOI: https://doi.org/10.1124/dmd.109.028225
Fischer, James H.
- You have accessUp-Regulation of UDP-Glucuronosyltransferase (UGT) 1A4 by 17β-Estradiol: A Potential Mechanism of Increased Lamotrigine Elimination in PregnancyHuiqing Chen, Kyunghee Yang, Suyoung Choi, James H. Fischer and Hyunyoung JeongDrug Metabolism and Disposition September 2009, 37 (9) 1841-1847; DOI: https://doi.org/10.1124/dmd.109.026609
Foti, Robert S.
- You have accessIn Vitro Inhibition of Multiple Cytochrome P450 Isoforms by Xanthone Derivatives from Mangosteen ExtractRobert S. Foti, Josh T. Pearson, Dan A. Rock, Jan L. Wahlstrom and Larry C. WienkersDrug Metabolism and Disposition September 2009, 37 (9) 1848-1855; DOI: https://doi.org/10.1124/dmd.109.028043
Fried, Michael
- You have accessChanges in mRNA Expression Levels of Solute Carrier Transporters in Inflammatory Bowel Disease PatientsKacper A. Wojtal, Jyrki J. Eloranta, Petr Hruz, Heike Gutmann, Jürgen Drewe, Alex Staumann, Christoph Beglinger, Michael Fried, Gerd A. Kullak-Ublick and Stephan R. VavrickaDrug Metabolism and Disposition September 2009, 37 (9) 1871-1877; DOI: https://doi.org/10.1124/dmd.109.027367
Fujimaki, Yuko
- You have accessMetabolism of Ticlopidine in Rats: Identification of the Main Biliary Metabolite as a Glutathione Conjugate of Ticlopidine S-OxideShinji Shimizu, Ryo Atsumi, Tsunenori Nakazawa, Yuko Fujimaki, Kenichi Sudo and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1904-1915; DOI: https://doi.org/10.1124/dmd.109.027524
G
Goldsmith, Michael-Rock
- You have accessContrasting Influence of NADPH and a NADPH-Regenerating System on the Metabolism of Carbonyl-Containing Compounds in Hepatic MicrosomesChristopher S. Mazur, John F. Kenneke, Michael-Rock Goldsmith and Cather BrownDrug Metabolism and Disposition September 2009, 37 (9) 1801-1805; DOI: https://doi.org/10.1124/dmd.109.027615
Guillemette, Chantal
- You have accessGlucuronidation of the Antiretroviral Drug Efavirenz by UGT2B7 and an in Vitro Investigation of Drug-Drug Interaction with ZidovudineAnne-Sophie Bélanger, Patrick Caron, Mario Harvey, Peter A. Zimmerman, Rajeev K. Mehlotra and Chantal GuillemetteDrug Metabolism and Disposition September 2009, 37 (9) 1793-1796; DOI: https://doi.org/10.1124/dmd.109.027706
Gutmann, Heike
- You have accessChanges in mRNA Expression Levels of Solute Carrier Transporters in Inflammatory Bowel Disease PatientsKacper A. Wojtal, Jyrki J. Eloranta, Petr Hruz, Heike Gutmann, Jürgen Drewe, Alex Staumann, Christoph Beglinger, Michael Fried, Gerd A. Kullak-Ublick and Stephan R. VavrickaDrug Metabolism and Disposition September 2009, 37 (9) 1871-1877; DOI: https://doi.org/10.1124/dmd.109.027367
H
Harakawa, Noriko
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Harvey, Mario
- You have accessGlucuronidation of the Antiretroviral Drug Efavirenz by UGT2B7 and an in Vitro Investigation of Drug-Drug Interaction with ZidovudineAnne-Sophie Bélanger, Patrick Caron, Mario Harvey, Peter A. Zimmerman, Rajeev K. Mehlotra and Chantal GuillemetteDrug Metabolism and Disposition September 2009, 37 (9) 1793-1796; DOI: https://doi.org/10.1124/dmd.109.027706
Hasegawa, Ryuichi
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Haupt, Lois
- You have accessAn in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 EnzymesAlaa-Eldin F. Nassar, Ivan King, Brandy L. Paris, Lois Haupt, Florence Ndikum-Moffor, Rebecca Campbell, Etsuko Usuki, Jennifer Skibbe, Dan Brobst, Brian W. Ogilvie and Andrew ParkinsonDrug Metabolism and Disposition September 2009, 37 (9) 1922-1930; DOI: https://doi.org/10.1124/dmd.109.027516
Hay, Tanya
- You have accessModulation of the Partition Coefficient between Octanol and Buffer at pH 7.4 and pKa to Achieve the Optimum Balance of Blood Clearance and Volume of Distribution for a Series of Tetrahydropyran Histamine Type 3 Receptor AntagonistsTanya Hay, Rhys Jones, Kevin Beaumont and Mark KempDrug Metabolism and Disposition September 2009, 37 (9) 1864-1870; DOI: https://doi.org/10.1124/dmd.109.027888
Heine, R. ter
- You have accessIdentification and Profiling of Circulating Metabolites of Atazanavir, a HIV Protease InhibitorR. ter Heine, M. J. X. Hillebrand, H. Rosing, E. C. M. van Gorp, J. W. Mulder, J. H. Beijnen and A. D. R. HuitemaDrug Metabolism and Disposition September 2009, 37 (9) 1826-1840; DOI: https://doi.org/10.1124/dmd.109.028258
Herédi-Szabó, Krisztina
- You have accessEffect of Membrane Cholesterol on BSEP/Bsep Activity: Species Specificity Studies for Substrates and InhibitorsEmese Kis, Enikő Ioja, Tunde Nagy, Lajos Szente, Krisztina Herédi-Szabó and Péter KrajcsiDrug Metabolism and Disposition September 2009, 37 (9) 1878-1886; DOI: https://doi.org/10.1124/dmd.108.024778
Hillebrand, M. J. X.
- You have accessIdentification and Profiling of Circulating Metabolites of Atazanavir, a HIV Protease InhibitorR. ter Heine, M. J. X. Hillebrand, H. Rosing, E. C. M. van Gorp, J. W. Mulder, J. H. Beijnen and A. D. R. HuitemaDrug Metabolism and Disposition September 2009, 37 (9) 1826-1840; DOI: https://doi.org/10.1124/dmd.109.028258
Hruz, Petr
- You have accessChanges in mRNA Expression Levels of Solute Carrier Transporters in Inflammatory Bowel Disease PatientsKacper A. Wojtal, Jyrki J. Eloranta, Petr Hruz, Heike Gutmann, Jürgen Drewe, Alex Staumann, Christoph Beglinger, Michael Fried, Gerd A. Kullak-Ublick and Stephan R. VavrickaDrug Metabolism and Disposition September 2009, 37 (9) 1871-1877; DOI: https://doi.org/10.1124/dmd.109.027367
Huitema, A. D. R.
- You have accessIdentification and Profiling of Circulating Metabolites of Atazanavir, a HIV Protease InhibitorR. ter Heine, M. J. X. Hillebrand, H. Rosing, E. C. M. van Gorp, J. W. Mulder, J. H. Beijnen and A. D. R. HuitemaDrug Metabolism and Disposition September 2009, 37 (9) 1826-1840; DOI: https://doi.org/10.1124/dmd.109.028258
I
Inoue, Kazuko
- You have accessAromatic Substitution Reaction of 2-Chloropyridines Catalyzed by Microsomal Glutathione S-Transferase 1Kazuko Inoue, Tomoyuki Ohe, Kenichi Mori, Takeshi Sagara, Yasuyuki Ishii and Masato ChibaDrug Metabolism and Disposition September 2009, 37 (9) 1797-1800; DOI: https://doi.org/10.1124/dmd.109.027698
Ioja, Enikő
- You have accessEffect of Membrane Cholesterol on BSEP/Bsep Activity: Species Specificity Studies for Substrates and InhibitorsEmese Kis, Enikő Ioja, Tunde Nagy, Lajos Szente, Krisztina Herédi-Szabó and Péter KrajcsiDrug Metabolism and Disposition September 2009, 37 (9) 1878-1886; DOI: https://doi.org/10.1124/dmd.108.024778
Ishii, Yasuyuki
- You have accessAromatic Substitution Reaction of 2-Chloropyridines Catalyzed by Microsomal Glutathione S-Transferase 1Kazuko Inoue, Tomoyuki Ohe, Kenichi Mori, Takeshi Sagara, Yasuyuki Ishii and Masato ChibaDrug Metabolism and Disposition September 2009, 37 (9) 1797-1800; DOI: https://doi.org/10.1124/dmd.109.027698
Iwai, Megumi
- You have accessInvolvement of Human Organic Cation Transporter 1 in the Hepatic Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel, Small Molecule Survivin SuppressantMegumi Iwai, Tsuyoshi Minematsu, Shinichi Narikawa, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition September 2009, 37 (9) 1856-1863; DOI: https://doi.org/10.1124/dmd.109.027359
J
Jeong, Hyunyoung
- You have accessUp-Regulation of UDP-Glucuronosyltransferase (UGT) 1A4 by 17β-Estradiol: A Potential Mechanism of Increased Lamotrigine Elimination in PregnancyHuiqing Chen, Kyunghee Yang, Suyoung Choi, James H. Fischer and Hyunyoung JeongDrug Metabolism and Disposition September 2009, 37 (9) 1841-1847; DOI: https://doi.org/10.1124/dmd.109.026609
Jiang, Yan
- You have accessAge- and Sex-Related Expression and Activity of Carboxylesterase 1 and 2 in Mouse and Human LiverHao-Jie Zhu, David I. Appel, Yan Jiang and John S. MarkowitzDrug Metabolism and Disposition September 2009, 37 (9) 1819-1825; DOI: https://doi.org/10.1124/dmd.109.028209
Jones, Rhys
- You have accessModulation of the Partition Coefficient between Octanol and Buffer at pH 7.4 and pKa to Achieve the Optimum Balance of Blood Clearance and Volume of Distribution for a Series of Tetrahydropyran Histamine Type 3 Receptor AntagonistsTanya Hay, Rhys Jones, Kevin Beaumont and Mark KempDrug Metabolism and Disposition September 2009, 37 (9) 1864-1870; DOI: https://doi.org/10.1124/dmd.109.027888
K
Kamide, Kei
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Kamimura, Hidetaka
- You have accessInvolvement of Human Organic Cation Transporter 1 in the Hepatic Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel, Small Molecule Survivin SuppressantMegumi Iwai, Tsuyoshi Minematsu, Shinichi Narikawa, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition September 2009, 37 (9) 1856-1863; DOI: https://doi.org/10.1124/dmd.109.027359
Kamiyama, Emi
- You have accessCulture Period-Dependent Change of Function and Expression of ATP-Binding Cassette Transporters in Caco-2 CellsEmi Kamiyama, Daisuke Sugiyama, Daisuke Nakai, Shin-ichi Miura and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1956-1962; DOI: https://doi.org/10.1124/dmd.109.027490
Kaniwa, Nahoko
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Katori, Noriko
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Kemp, Mark
- You have accessModulation of the Partition Coefficient between Octanol and Buffer at pH 7.4 and pKa to Achieve the Optimum Balance of Blood Clearance and Volume of Distribution for a Series of Tetrahydropyran Histamine Type 3 Receptor AntagonistsTanya Hay, Rhys Jones, Kevin Beaumont and Mark KempDrug Metabolism and Disposition September 2009, 37 (9) 1864-1870; DOI: https://doi.org/10.1124/dmd.109.027888
Kenneke, John F.
- You have accessContrasting Influence of NADPH and a NADPH-Regenerating System on the Metabolism of Carbonyl-Containing Compounds in Hepatic MicrosomesChristopher S. Mazur, John F. Kenneke, Michael-Rock Goldsmith and Cather BrownDrug Metabolism and Disposition September 2009, 37 (9) 1801-1805; DOI: https://doi.org/10.1124/dmd.109.027615
Kerdpin, Oranun
- You have accessInfluence of N-Terminal Domain Histidine and Proline Residues on the Substrate Selectivities of Human UDP-Glucuronosyltransferase 1A1, 1A6, 1A9, 2B7, and 2B10Oranun Kerdpin, Peter I. Mackenzie, Kushari Bowalgaha, Moshe Finel and John O. MinersDrug Metabolism and Disposition September 2009, 37 (9) 1948-1955; DOI: https://doi.org/10.1124/dmd.109.028225
Kim, Su-Ryang
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
King, Ivan
- You have accessAn in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 EnzymesAlaa-Eldin F. Nassar, Ivan King, Brandy L. Paris, Lois Haupt, Florence Ndikum-Moffor, Rebecca Campbell, Etsuko Usuki, Jennifer Skibbe, Dan Brobst, Brian W. Ogilvie and Andrew ParkinsonDrug Metabolism and Disposition September 2009, 37 (9) 1922-1930; DOI: https://doi.org/10.1124/dmd.109.027516
Kis, Emese
- You have accessEffect of Membrane Cholesterol on BSEP/Bsep Activity: Species Specificity Studies for Substrates and InhibitorsEmese Kis, Enikő Ioja, Tunde Nagy, Lajos Szente, Krisztina Herédi-Szabó and Péter KrajcsiDrug Metabolism and Disposition September 2009, 37 (9) 1878-1886; DOI: https://doi.org/10.1124/dmd.108.024778
Klaassen, Curtis D.
- You have accessGenetic Polymorphisms in the TATA Box and Upstream Phenobarbital-Responsive Enhancer Module of the UGT1A1 Promoter Have Combined Effects on UDP-Glucuronosyltransferase 1A1 Transcription Mediated by Constitutive Androstane Receptor, Pregnane X Receptor, or Glucocorticoid Receptor in Human LiverYe Li, David Buckley, Shuang Wang, Curtis D. Klaassen and Xiao-bo ZhongDrug Metabolism and Disposition September 2009, 37 (9) 1978-1986; DOI: https://doi.org/10.1124/dmd.109.027409
Kobayashi, Yoshimasa
- You have accessA Zone Classification System for Risk Assessment of Idiosyncratic Drug Toxicity Using Daily Dose and Covalent BindingShintaro Nakayama, Ryo Atsumi, Hideo Takakusa, Yoshimasa Kobayashi, Atsushi Kurihara, Yoko Nagai, Daisuke Nakai and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1970-1977; DOI: https://doi.org/10.1124/dmd.109.027797
Kon, Junko
- You have accessThyroid Hormone Is Necessary for Expression of Constitutive Androstane Receptor in Rat HepatocytesHidekazu Ooe, Junko Kon, Hideki Oshima and Toshihiro MitakaDrug Metabolism and Disposition September 2009, 37 (9) 1963-1969; DOI: https://doi.org/10.1124/dmd.108.022905
Krajcsi, Péter
- You have accessEffect of Membrane Cholesterol on BSEP/Bsep Activity: Species Specificity Studies for Substrates and InhibitorsEmese Kis, Enikő Ioja, Tunde Nagy, Lajos Szente, Krisztina Herédi-Szabó and Péter KrajcsiDrug Metabolism and Disposition September 2009, 37 (9) 1878-1886; DOI: https://doi.org/10.1124/dmd.108.024778
Kullak-Ublick, Gerd A.
- You have accessChanges in mRNA Expression Levels of Solute Carrier Transporters in Inflammatory Bowel Disease PatientsKacper A. Wojtal, Jyrki J. Eloranta, Petr Hruz, Heike Gutmann, Jürgen Drewe, Alex Staumann, Christoph Beglinger, Michael Fried, Gerd A. Kullak-Ublick and Stephan R. VavrickaDrug Metabolism and Disposition September 2009, 37 (9) 1871-1877; DOI: https://doi.org/10.1124/dmd.109.027367
Kurihara, Atsushi
- You have accessA Zone Classification System for Risk Assessment of Idiosyncratic Drug Toxicity Using Daily Dose and Covalent BindingShintaro Nakayama, Ryo Atsumi, Hideo Takakusa, Yoshimasa Kobayashi, Atsushi Kurihara, Yoko Nagai, Daisuke Nakai and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1970-1977; DOI: https://doi.org/10.1124/dmd.109.027797
L
Lau, Aik Jiang
- You have accessInhibition of Human CYP2B6-Catalyzed Bupropion Hydroxylation by Ginkgo biloba Extract: Effect of Terpene Trilactones and FlavonolsAik Jiang Lau and Thomas K. H. ChangDrug Metabolism and Disposition September 2009, 37 (9) 1931-1937; DOI: https://doi.org/10.1124/dmd.109.028118
Lee, Jin Kyung
- You have accessSex-Dependent Disposition of Acetaminophen Sulfate and Glucuronide in the in Situ Perfused Mouse LiverJin Kyung Lee, Koji Abe, Arlene S. Bridges, Nita J. Patel, Thomas J. Raub, Gary M. Pollack and Kim L. R. BrouwerDrug Metabolism and Disposition September 2009, 37 (9) 1916-1921; DOI: https://doi.org/10.1124/dmd.109.026815
Li, Haishan
- You have accessMethadone Induces the Expression of Hepatic Drug-Metabolizing Enzymes through the Activation of Pregnane X Receptor and Constitutive Androstane ReceptorAntonia H. Tolson, Haishan Li, Natalie D. Eddington and Hongbing WangDrug Metabolism and Disposition September 2009, 37 (9) 1887-1894; DOI: https://doi.org/10.1124/dmd.109.027854
Li, Ye
- You have accessGenetic Polymorphisms in the TATA Box and Upstream Phenobarbital-Responsive Enhancer Module of the UGT1A1 Promoter Have Combined Effects on UDP-Glucuronosyltransferase 1A1 Transcription Mediated by Constitutive Androstane Receptor, Pregnane X Receptor, or Glucocorticoid Receptor in Human LiverYe Li, David Buckley, Shuang Wang, Curtis D. Klaassen and Xiao-bo ZhongDrug Metabolism and Disposition September 2009, 37 (9) 1978-1986; DOI: https://doi.org/10.1124/dmd.109.027409
M
Mackenzie, Peter I.
- You have accessInfluence of N-Terminal Domain Histidine and Proline Residues on the Substrate Selectivities of Human UDP-Glucuronosyltransferase 1A1, 1A6, 1A9, 2B7, and 2B10Oranun Kerdpin, Peter I. Mackenzie, Kushari Bowalgaha, Moshe Finel and John O. MinersDrug Metabolism and Disposition September 2009, 37 (9) 1948-1955; DOI: https://doi.org/10.1124/dmd.109.028225
Maekawa, Keiko
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Mannargudi, Baskar
- You have accessBioactivation of Minocycline to Reactive Intermediates by Myeloperoxidase, Horseradish Peroxidase, and Hepatic Microsomes: Implications for Minocycline-Induced Lupus and HepatitisBaskar Mannargudi, David McNally, William Reynolds and Jack UetrechtDrug Metabolism and Disposition September 2009, 37 (9) 1806-1818; DOI: https://doi.org/10.1124/dmd.109.027292
Markowitz, John S.
- You have accessAge- and Sex-Related Expression and Activity of Carboxylesterase 1 and 2 in Mouse and Human LiverHao-Jie Zhu, David I. Appel, Yan Jiang and John S. MarkowitzDrug Metabolism and Disposition September 2009, 37 (9) 1819-1825; DOI: https://doi.org/10.1124/dmd.109.028209
Mazur, Christopher S.
- You have accessContrasting Influence of NADPH and a NADPH-Regenerating System on the Metabolism of Carbonyl-Containing Compounds in Hepatic MicrosomesChristopher S. Mazur, John F. Kenneke, Michael-Rock Goldsmith and Cather BrownDrug Metabolism and Disposition September 2009, 37 (9) 1801-1805; DOI: https://doi.org/10.1124/dmd.109.027615
McNally, David
- You have accessBioactivation of Minocycline to Reactive Intermediates by Myeloperoxidase, Horseradish Peroxidase, and Hepatic Microsomes: Implications for Minocycline-Induced Lupus and HepatitisBaskar Mannargudi, David McNally, William Reynolds and Jack UetrechtDrug Metabolism and Disposition September 2009, 37 (9) 1806-1818; DOI: https://doi.org/10.1124/dmd.109.027292
Mehlotra, Rajeev K.
- You have accessGlucuronidation of the Antiretroviral Drug Efavirenz by UGT2B7 and an in Vitro Investigation of Drug-Drug Interaction with ZidovudineAnne-Sophie Bélanger, Patrick Caron, Mario Harvey, Peter A. Zimmerman, Rajeev K. Mehlotra and Chantal GuillemetteDrug Metabolism and Disposition September 2009, 37 (9) 1793-1796; DOI: https://doi.org/10.1124/dmd.109.027706
Minematsu, Tsuyoshi
- You have accessInvolvement of Human Organic Cation Transporter 1 in the Hepatic Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel, Small Molecule Survivin SuppressantMegumi Iwai, Tsuyoshi Minematsu, Shinichi Narikawa, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition September 2009, 37 (9) 1856-1863; DOI: https://doi.org/10.1124/dmd.109.027359
Miners, John O.
- You have accessInfluence of N-Terminal Domain Histidine and Proline Residues on the Substrate Selectivities of Human UDP-Glucuronosyltransferase 1A1, 1A6, 1A9, 2B7, and 2B10Oranun Kerdpin, Peter I. Mackenzie, Kushari Bowalgaha, Moshe Finel and John O. MinersDrug Metabolism and Disposition September 2009, 37 (9) 1948-1955; DOI: https://doi.org/10.1124/dmd.109.028225
Mitaka, Toshihiro
- You have accessThyroid Hormone Is Necessary for Expression of Constitutive Androstane Receptor in Rat HepatocytesHidekazu Ooe, Junko Kon, Hideki Oshima and Toshihiro MitakaDrug Metabolism and Disposition September 2009, 37 (9) 1963-1969; DOI: https://doi.org/10.1124/dmd.108.022905
Miura, Shin-ichi
- You have accessCulture Period-Dependent Change of Function and Expression of ATP-Binding Cassette Transporters in Caco-2 CellsEmi Kamiyama, Daisuke Sugiyama, Daisuke Nakai, Shin-ichi Miura and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1956-1962; DOI: https://doi.org/10.1124/dmd.109.027490
Miyata, Toshiyuki
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Mori, Kenichi
- You have accessAromatic Substitution Reaction of 2-Chloropyridines Catalyzed by Microsomal Glutathione S-Transferase 1Kazuko Inoue, Tomoyuki Ohe, Kenichi Mori, Takeshi Sagara, Yasuyuki Ishii and Masato ChibaDrug Metabolism and Disposition September 2009, 37 (9) 1797-1800; DOI: https://doi.org/10.1124/dmd.109.027698
Mulder, J. W.
- You have accessIdentification and Profiling of Circulating Metabolites of Atazanavir, a HIV Protease InhibitorR. ter Heine, M. J. X. Hillebrand, H. Rosing, E. C. M. van Gorp, J. W. Mulder, J. H. Beijnen and A. D. R. HuitemaDrug Metabolism and Disposition September 2009, 37 (9) 1826-1840; DOI: https://doi.org/10.1124/dmd.109.028258
N
Nagai, Yoko
- You have accessA Zone Classification System for Risk Assessment of Idiosyncratic Drug Toxicity Using Daily Dose and Covalent BindingShintaro Nakayama, Ryo Atsumi, Hideo Takakusa, Yoshimasa Kobayashi, Atsushi Kurihara, Yoko Nagai, Daisuke Nakai and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1970-1977; DOI: https://doi.org/10.1124/dmd.109.027797
Nagy, Tunde
- You have accessEffect of Membrane Cholesterol on BSEP/Bsep Activity: Species Specificity Studies for Substrates and InhibitorsEmese Kis, Enikő Ioja, Tunde Nagy, Lajos Szente, Krisztina Herédi-Szabó and Péter KrajcsiDrug Metabolism and Disposition September 2009, 37 (9) 1878-1886; DOI: https://doi.org/10.1124/dmd.108.024778
Nakai, Daisuke
- You have accessCulture Period-Dependent Change of Function and Expression of ATP-Binding Cassette Transporters in Caco-2 CellsEmi Kamiyama, Daisuke Sugiyama, Daisuke Nakai, Shin-ichi Miura and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1956-1962; DOI: https://doi.org/10.1124/dmd.109.027490
- You have accessA Zone Classification System for Risk Assessment of Idiosyncratic Drug Toxicity Using Daily Dose and Covalent BindingShintaro Nakayama, Ryo Atsumi, Hideo Takakusa, Yoshimasa Kobayashi, Atsushi Kurihara, Yoko Nagai, Daisuke Nakai and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1970-1977; DOI: https://doi.org/10.1124/dmd.109.027797
Nakayama, Shintaro
- You have accessA Zone Classification System for Risk Assessment of Idiosyncratic Drug Toxicity Using Daily Dose and Covalent BindingShintaro Nakayama, Ryo Atsumi, Hideo Takakusa, Yoshimasa Kobayashi, Atsushi Kurihara, Yoko Nagai, Daisuke Nakai and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1970-1977; DOI: https://doi.org/10.1124/dmd.109.027797
Nakazawa, Tsunenori
- You have accessMetabolism of Ticlopidine in Rats: Identification of the Main Biliary Metabolite as a Glutathione Conjugate of Ticlopidine S-OxideShinji Shimizu, Ryo Atsumi, Tsunenori Nakazawa, Yuko Fujimaki, Kenichi Sudo and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1904-1915; DOI: https://doi.org/10.1124/dmd.109.027524
Narikawa, Shinichi
- You have accessInvolvement of Human Organic Cation Transporter 1 in the Hepatic Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel, Small Molecule Survivin SuppressantMegumi Iwai, Tsuyoshi Minematsu, Shinichi Narikawa, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition September 2009, 37 (9) 1856-1863; DOI: https://doi.org/10.1124/dmd.109.027359
Nassar, Alaa-Eldin F.
- You have accessAn in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 EnzymesAlaa-Eldin F. Nassar, Ivan King, Brandy L. Paris, Lois Haupt, Florence Ndikum-Moffor, Rebecca Campbell, Etsuko Usuki, Jennifer Skibbe, Dan Brobst, Brian W. Ogilvie and Andrew ParkinsonDrug Metabolism and Disposition September 2009, 37 (9) 1922-1930; DOI: https://doi.org/10.1124/dmd.109.027516
Ndikum-Moffor, Florence
- You have accessAn in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 EnzymesAlaa-Eldin F. Nassar, Ivan King, Brandy L. Paris, Lois Haupt, Florence Ndikum-Moffor, Rebecca Campbell, Etsuko Usuki, Jennifer Skibbe, Dan Brobst, Brian W. Ogilvie and Andrew ParkinsonDrug Metabolism and Disposition September 2009, 37 (9) 1922-1930; DOI: https://doi.org/10.1124/dmd.109.027516
O
Ogilvie, Brian W.
- You have accessAn in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 EnzymesAlaa-Eldin F. Nassar, Ivan King, Brandy L. Paris, Lois Haupt, Florence Ndikum-Moffor, Rebecca Campbell, Etsuko Usuki, Jennifer Skibbe, Dan Brobst, Brian W. Ogilvie and Andrew ParkinsonDrug Metabolism and Disposition September 2009, 37 (9) 1922-1930; DOI: https://doi.org/10.1124/dmd.109.027516
Ohe, Tomoyuki
- You have accessAromatic Substitution Reaction of 2-Chloropyridines Catalyzed by Microsomal Glutathione S-Transferase 1Kazuko Inoue, Tomoyuki Ohe, Kenichi Mori, Takeshi Sagara, Yasuyuki Ishii and Masato ChibaDrug Metabolism and Disposition September 2009, 37 (9) 1797-1800; DOI: https://doi.org/10.1124/dmd.109.027698
Okazaki, Osamu
- You have accessMetabolism of Ticlopidine in Rats: Identification of the Main Biliary Metabolite as a Glutathione Conjugate of Ticlopidine S-OxideShinji Shimizu, Ryo Atsumi, Tsunenori Nakazawa, Yuko Fujimaki, Kenichi Sudo and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1904-1915; DOI: https://doi.org/10.1124/dmd.109.027524
- You have accessCulture Period-Dependent Change of Function and Expression of ATP-Binding Cassette Transporters in Caco-2 CellsEmi Kamiyama, Daisuke Sugiyama, Daisuke Nakai, Shin-ichi Miura and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1956-1962; DOI: https://doi.org/10.1124/dmd.109.027490
- You have accessA Zone Classification System for Risk Assessment of Idiosyncratic Drug Toxicity Using Daily Dose and Covalent BindingShintaro Nakayama, Ryo Atsumi, Hideo Takakusa, Yoshimasa Kobayashi, Atsushi Kurihara, Yoko Nagai, Daisuke Nakai and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1970-1977; DOI: https://doi.org/10.1124/dmd.109.027797
Ooe, Hidekazu
- You have accessThyroid Hormone Is Necessary for Expression of Constitutive Androstane Receptor in Rat HepatocytesHidekazu Ooe, Junko Kon, Hideki Oshima and Toshihiro MitakaDrug Metabolism and Disposition September 2009, 37 (9) 1963-1969; DOI: https://doi.org/10.1124/dmd.108.022905
Oshima, Hideki
- You have accessThyroid Hormone Is Necessary for Expression of Constitutive Androstane Receptor in Rat HepatocytesHidekazu Ooe, Junko Kon, Hideki Oshima and Toshihiro MitakaDrug Metabolism and Disposition September 2009, 37 (9) 1963-1969; DOI: https://doi.org/10.1124/dmd.108.022905
P
Paris, Brandy L.
- You have accessAn in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 EnzymesAlaa-Eldin F. Nassar, Ivan King, Brandy L. Paris, Lois Haupt, Florence Ndikum-Moffor, Rebecca Campbell, Etsuko Usuki, Jennifer Skibbe, Dan Brobst, Brian W. Ogilvie and Andrew ParkinsonDrug Metabolism and Disposition September 2009, 37 (9) 1922-1930; DOI: https://doi.org/10.1124/dmd.109.027516
Parkinson, Andrew
- You have accessAn in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 EnzymesAlaa-Eldin F. Nassar, Ivan King, Brandy L. Paris, Lois Haupt, Florence Ndikum-Moffor, Rebecca Campbell, Etsuko Usuki, Jennifer Skibbe, Dan Brobst, Brian W. Ogilvie and Andrew ParkinsonDrug Metabolism and Disposition September 2009, 37 (9) 1922-1930; DOI: https://doi.org/10.1124/dmd.109.027516
Patel, Nita J.
- You have accessSex-Dependent Disposition of Acetaminophen Sulfate and Glucuronide in the in Situ Perfused Mouse LiverJin Kyung Lee, Koji Abe, Arlene S. Bridges, Nita J. Patel, Thomas J. Raub, Gary M. Pollack and Kim L. R. BrouwerDrug Metabolism and Disposition September 2009, 37 (9) 1916-1921; DOI: https://doi.org/10.1124/dmd.109.026815
Pearson, Josh T.
- You have accessIn Vitro Inhibition of Multiple Cytochrome P450 Isoforms by Xanthone Derivatives from Mangosteen ExtractRobert S. Foti, Josh T. Pearson, Dan A. Rock, Jan L. Wahlstrom and Larry C. WienkersDrug Metabolism and Disposition September 2009, 37 (9) 1848-1855; DOI: https://doi.org/10.1124/dmd.109.028043
Pollack, Gary M.
- You have accessSex-Dependent Disposition of Acetaminophen Sulfate and Glucuronide in the in Situ Perfused Mouse LiverJin Kyung Lee, Koji Abe, Arlene S. Bridges, Nita J. Patel, Thomas J. Raub, Gary M. Pollack and Kim L. R. BrouwerDrug Metabolism and Disposition September 2009, 37 (9) 1916-1921; DOI: https://doi.org/10.1124/dmd.109.026815
R
Raub, Thomas J.
- You have accessSex-Dependent Disposition of Acetaminophen Sulfate and Glucuronide in the in Situ Perfused Mouse LiverJin Kyung Lee, Koji Abe, Arlene S. Bridges, Nita J. Patel, Thomas J. Raub, Gary M. Pollack and Kim L. R. BrouwerDrug Metabolism and Disposition September 2009, 37 (9) 1916-1921; DOI: https://doi.org/10.1124/dmd.109.026815
Reynolds, William
- You have accessBioactivation of Minocycline to Reactive Intermediates by Myeloperoxidase, Horseradish Peroxidase, and Hepatic Microsomes: Implications for Minocycline-Induced Lupus and HepatitisBaskar Mannargudi, David McNally, William Reynolds and Jack UetrechtDrug Metabolism and Disposition September 2009, 37 (9) 1806-1818; DOI: https://doi.org/10.1124/dmd.109.027292
Rock, Dan A.
- You have accessIn Vitro Inhibition of Multiple Cytochrome P450 Isoforms by Xanthone Derivatives from Mangosteen ExtractRobert S. Foti, Josh T. Pearson, Dan A. Rock, Jan L. Wahlstrom and Larry C. WienkersDrug Metabolism and Disposition September 2009, 37 (9) 1848-1855; DOI: https://doi.org/10.1124/dmd.109.028043
Rosing, H.
- You have accessIdentification and Profiling of Circulating Metabolites of Atazanavir, a HIV Protease InhibitorR. ter Heine, M. J. X. Hillebrand, H. Rosing, E. C. M. van Gorp, J. W. Mulder, J. H. Beijnen and A. D. R. HuitemaDrug Metabolism and Disposition September 2009, 37 (9) 1826-1840; DOI: https://doi.org/10.1124/dmd.109.028258
S
Sagara, Takeshi
- You have accessAromatic Substitution Reaction of 2-Chloropyridines Catalyzed by Microsomal Glutathione S-Transferase 1Kazuko Inoue, Tomoyuki Ohe, Kenichi Mori, Takeshi Sagara, Yasuyuki Ishii and Masato ChibaDrug Metabolism and Disposition September 2009, 37 (9) 1797-1800; DOI: https://doi.org/10.1124/dmd.109.027698
Saito, Yoshiro
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Sawada, Jun-ichi
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Shimizu, Shinji
- You have accessMetabolism of Ticlopidine in Rats: Identification of the Main Biliary Metabolite as a Glutathione Conjugate of Ticlopidine S-OxideShinji Shimizu, Ryo Atsumi, Tsunenori Nakazawa, Yuko Fujimaki, Kenichi Sudo and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1904-1915; DOI: https://doi.org/10.1124/dmd.109.027524
Skibbe, Jennifer
- You have accessAn in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 EnzymesAlaa-Eldin F. Nassar, Ivan King, Brandy L. Paris, Lois Haupt, Florence Ndikum-Moffor, Rebecca Campbell, Etsuko Usuki, Jennifer Skibbe, Dan Brobst, Brian W. Ogilvie and Andrew ParkinsonDrug Metabolism and Disposition September 2009, 37 (9) 1922-1930; DOI: https://doi.org/10.1124/dmd.109.027516
Staumann, Alex
- You have accessChanges in mRNA Expression Levels of Solute Carrier Transporters in Inflammatory Bowel Disease PatientsKacper A. Wojtal, Jyrki J. Eloranta, Petr Hruz, Heike Gutmann, Jürgen Drewe, Alex Staumann, Christoph Beglinger, Michael Fried, Gerd A. Kullak-Ublick and Stephan R. VavrickaDrug Metabolism and Disposition September 2009, 37 (9) 1871-1877; DOI: https://doi.org/10.1124/dmd.109.027367
Sudo, Kenichi
- You have accessMetabolism of Ticlopidine in Rats: Identification of the Main Biliary Metabolite as a Glutathione Conjugate of Ticlopidine S-OxideShinji Shimizu, Ryo Atsumi, Tsunenori Nakazawa, Yuko Fujimaki, Kenichi Sudo and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1904-1915; DOI: https://doi.org/10.1124/dmd.109.027524
Sugiyama, Daisuke
- You have accessCulture Period-Dependent Change of Function and Expression of ATP-Binding Cassette Transporters in Caco-2 CellsEmi Kamiyama, Daisuke Sugiyama, Daisuke Nakai, Shin-ichi Miura and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1956-1962; DOI: https://doi.org/10.1124/dmd.109.027490
Sugiyama, Emiko
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Szente, Lajos
- You have accessEffect of Membrane Cholesterol on BSEP/Bsep Activity: Species Specificity Studies for Substrates and InhibitorsEmese Kis, Enikő Ioja, Tunde Nagy, Lajos Szente, Krisztina Herédi-Szabó and Péter KrajcsiDrug Metabolism and Disposition September 2009, 37 (9) 1878-1886; DOI: https://doi.org/10.1124/dmd.108.024778
T
Takakusa, Hideo
- You have accessA Zone Classification System for Risk Assessment of Idiosyncratic Drug Toxicity Using Daily Dose and Covalent BindingShintaro Nakayama, Ryo Atsumi, Hideo Takakusa, Yoshimasa Kobayashi, Atsushi Kurihara, Yoko Nagai, Daisuke Nakai and Osamu OkazakiDrug Metabolism and Disposition September 2009, 37 (9) 1970-1977; DOI: https://doi.org/10.1124/dmd.109.027797
Tohkin, Masahiro
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Tolson, Antonia H.
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Uetrecht, Jack
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Usui, Takashi
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Usuki, Etsuko
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van Gorp, E. C. M.
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Vavricka, Stephan R.
- You have accessChanges in mRNA Expression Levels of Solute Carrier Transporters in Inflammatory Bowel Disease PatientsKacper A. Wojtal, Jyrki J. Eloranta, Petr Hruz, Heike Gutmann, Jürgen Drewe, Alex Staumann, Christoph Beglinger, Michael Fried, Gerd A. Kullak-Ublick and Stephan R. VavrickaDrug Metabolism and Disposition September 2009, 37 (9) 1871-1877; DOI: https://doi.org/10.1124/dmd.109.027367
W
Wahlstrom, Jan L.
- You have accessIn Vitro Inhibition of Multiple Cytochrome P450 Isoforms by Xanthone Derivatives from Mangosteen ExtractRobert S. Foti, Josh T. Pearson, Dan A. Rock, Jan L. Wahlstrom and Larry C. WienkersDrug Metabolism and Disposition September 2009, 37 (9) 1848-1855; DOI: https://doi.org/10.1124/dmd.109.028043
Wang, Hongbing
- You have accessMethadone Induces the Expression of Hepatic Drug-Metabolizing Enzymes through the Activation of Pregnane X Receptor and Constitutive Androstane ReceptorAntonia H. Tolson, Haishan Li, Natalie D. Eddington and Hongbing WangDrug Metabolism and Disposition September 2009, 37 (9) 1887-1894; DOI: https://doi.org/10.1124/dmd.109.027854
Wang, Shuang
- You have accessGenetic Polymorphisms in the TATA Box and Upstream Phenobarbital-Responsive Enhancer Module of the UGT1A1 Promoter Have Combined Effects on UDP-Glucuronosyltransferase 1A1 Transcription Mediated by Constitutive Androstane Receptor, Pregnane X Receptor, or Glucocorticoid Receptor in Human LiverYe Li, David Buckley, Shuang Wang, Curtis D. Klaassen and Xiao-bo ZhongDrug Metabolism and Disposition September 2009, 37 (9) 1978-1986; DOI: https://doi.org/10.1124/dmd.109.027409
Wienkers, Larry C.
- You have accessIn Vitro Inhibition of Multiple Cytochrome P450 Isoforms by Xanthone Derivatives from Mangosteen ExtractRobert S. Foti, Josh T. Pearson, Dan A. Rock, Jan L. Wahlstrom and Larry C. WienkersDrug Metabolism and Disposition September 2009, 37 (9) 1848-1855; DOI: https://doi.org/10.1124/dmd.109.028043
Wojtal, Kacper A.
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Y
Yang, Kyunghee
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Yasuda, Kazuki
- You have accessSubstrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese SubjectsKeiko Maekawa, Noriko Harakawa, Emiko Sugiyama, Masahiro Tohkin, Su-Ryang Kim, Nahoko Kaniwa, Noriko Katori, Ryuichi Hasegawa, Kazuki Yasuda, Kei Kamide, Toshiyuki Miyata, Yoshiro Saito and Jun-ichi SawadaDrug Metabolism and Disposition September 2009, 37 (9) 1895-1903; DOI: https://doi.org/10.1124/dmd.109.027003
Z
Zhong, Xiao-bo
- You have accessGenetic Polymorphisms in the TATA Box and Upstream Phenobarbital-Responsive Enhancer Module of the UGT1A1 Promoter Have Combined Effects on UDP-Glucuronosyltransferase 1A1 Transcription Mediated by Constitutive Androstane Receptor, Pregnane X Receptor, or Glucocorticoid Receptor in Human LiverYe Li, David Buckley, Shuang Wang, Curtis D. Klaassen and Xiao-bo ZhongDrug Metabolism and Disposition September 2009, 37 (9) 1978-1986; DOI: https://doi.org/10.1124/dmd.109.027409
Zhu, Hao-Jie
- You have accessAge- and Sex-Related Expression and Activity of Carboxylesterase 1 and 2 in Mouse and Human LiverHao-Jie Zhu, David I. Appel, Yan Jiang and John S. MarkowitzDrug Metabolism and Disposition September 2009, 37 (9) 1819-1825; DOI: https://doi.org/10.1124/dmd.109.028209
Zimmerman, Peter A.
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