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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

January 01, 2010; Volume 38,Issue 1
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Aharony, David

    1. You have access
      Identification of Multiple Glutathione Conjugates of 8-Amino- 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline maleate (Nomifensine) in Liver Microsomes and Hepatocyte Preparations: Evidence of the Bioactivation of Nomifensine
      Jian Yu, Donald E. Mathisen, Doug Burdette, Dean G. Brown, Christopher Becker and David Aharony
      Drug Metabolism and Disposition January 2010, 38 (1) 46-60; DOI: https://doi.org/10.1124/dmd.109.028803
  2. Ahuja, Vijay T.

    1. You have access
      Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation
      Xiaoliang Zhuo, Richard A. Hartz, Joanne J. Bronson, Harvey Wong, Vijay T. Ahuja, Vivekana M. Vrudhula, John E. Leet, Stella Huang, John E. Macor and Yue-Zhong Shu
      Drug Metabolism and Disposition January 2010, 38 (1) 5-15; DOI: https://doi.org/10.1124/dmd.109.028910
  3. Andersson, Helén

    1. You have access
      Tamoxifen-Induced Adduct Formation and Cell Stress in Human Endometrial Glands
      Helén Andersson, Malin Helmestam, Anna Zebrowska, Matts Olovsson and Eva Brittebo
      Drug Metabolism and Disposition January 2010, 38 (1) 200-207; DOI: https://doi.org/10.1124/dmd.109.029488
  4. Annaert, Pieter P.

    1. You have access
      In Vitro Hepatic Metabolism Explains Higher Clearance of Voriconazole in Children versus Adults: Role of CYP2C19 and Flavin-Containing Monooxygenase 3
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Joseph G. Ibrahim, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition January 2010, 38 (1) 25-31; DOI: https://doi.org/10.1124/dmd.109.029769
  5. Anthony, Monique N.

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637
  6. Augustijns, Patrick

    1. You have access
      In Vitro Hepatic Metabolism Explains Higher Clearance of Voriconazole in Children versus Adults: Role of CYP2C19 and Flavin-Containing Monooxygenase 3
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Joseph G. Ibrahim, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition January 2010, 38 (1) 25-31; DOI: https://doi.org/10.1124/dmd.109.029769

B

  1. Bateman, Thomas J.

    1. You have access
      Glutathione S-Transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine
      Thomas J. Bateman, John S. Debenham, Christina Madsen-Duggan, Richard B. Toupence, Thomas F. Walsh, Quang Truong, Scott A. Bradley, George A. Doss, Sanjeev Kumar and Vijay Bhasker G. Reddy
      Drug Metabolism and Disposition January 2010, 38 (1) 108-114; DOI: https://doi.org/10.1124/dmd.109.029801
  2. Be, Xuhai

    1. You have access
      Prediction of Vss from In Vitro Tissue-Binding Studies
      Loren M. Berry, Jonathan Roberts, Xuhai Be, Zhiyang Zhao and Min-Hwa Jasmine Lin
      Drug Metabolism and Disposition January 2010, 38 (1) 115-121; DOI: https://doi.org/10.1124/dmd.109.029629
  3. Becker, Christopher

    1. You have access
      Identification of Multiple Glutathione Conjugates of 8-Amino- 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline maleate (Nomifensine) in Liver Microsomes and Hepatocyte Preparations: Evidence of the Bioactivation of Nomifensine
      Jian Yu, Donald E. Mathisen, Doug Burdette, Dean G. Brown, Christopher Becker and David Aharony
      Drug Metabolism and Disposition January 2010, 38 (1) 46-60; DOI: https://doi.org/10.1124/dmd.109.028803
  4. Bell, Jordan C.

    1. You have access
      Gene Regulation of CYP4F11 in Human Keratinocyte HaCaT Cells
      Ying Wang, Jordan C. Bell, Diane S. Keeney and Henry W. Strobel
      Drug Metabolism and Disposition January 2010, 38 (1) 100-107; DOI: https://doi.org/10.1124/dmd.109.029025
  5. Benet, Leslie Z.

    1. You have access
      Stereoselective Flunoxaprofen-S-acyl-glutathione Thioester Formation Mediated by Acyl-CoA Formation in Rat Hepatocytes
      Mark P. Grillo, Jill C. M. Wait, Michelle Tadano Lohr, Smriti Khera and Leslie Z. Benet
      Drug Metabolism and Disposition January 2010, 38 (1) 133-142; DOI: https://doi.org/10.1124/dmd.109.029371
  6. Benjamin, Daniel K.

    1. You have access
      In Vitro Hepatic Metabolism Explains Higher Clearance of Voriconazole in Children versus Adults: Role of CYP2C19 and Flavin-Containing Monooxygenase 3
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Joseph G. Ibrahim, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition January 2010, 38 (1) 25-31; DOI: https://doi.org/10.1124/dmd.109.029769
  7. Berry, Loren M.

    1. You have access
      Prediction of Vss from In Vitro Tissue-Binding Studies
      Loren M. Berry, Jonathan Roberts, Xuhai Be, Zhiyang Zhao and Min-Hwa Jasmine Lin
      Drug Metabolism and Disposition January 2010, 38 (1) 115-121; DOI: https://doi.org/10.1124/dmd.109.029629
  8. Bonn, Britta

    1. You have access
      Exploration of Catalytic Properties of CYP2D6 and CYP3A4 Through Metabolic Studies of Levorphanol and Levallorphan
      Britta Bonn, Collen M. Masimirembwa and Neal Castagnoli
      Drug Metabolism and Disposition January 2010, 38 (1) 187-199; DOI: https://doi.org/10.1124/dmd.109.028670
  9. Boudjelal, Mohamed

    1. You have access
      Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid
      Bryn M. Owen, Alexandra Milona, Saskia van Mil, Peter Clements, Julie Holder, Mohamed Boudjelal, William Cairns, Malcolm Parker, Roger White and Catherine Williamson
      Drug Metabolism and Disposition January 2010, 38 (1) 143-149; DOI: https://doi.org/10.1124/dmd.109.029306
  10. Bradley, Scott A.

    1. You have access
      Glutathione S-Transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine
      Thomas J. Bateman, John S. Debenham, Christina Madsen-Duggan, Richard B. Toupence, Thomas F. Walsh, Quang Truong, Scott A. Bradley, George A. Doss, Sanjeev Kumar and Vijay Bhasker G. Reddy
      Drug Metabolism and Disposition January 2010, 38 (1) 108-114; DOI: https://doi.org/10.1124/dmd.109.029801
  11. Brittebo, Eva

    1. You have access
      Tamoxifen-Induced Adduct Formation and Cell Stress in Human Endometrial Glands
      Helén Andersson, Malin Helmestam, Anna Zebrowska, Matts Olovsson and Eva Brittebo
      Drug Metabolism and Disposition January 2010, 38 (1) 200-207; DOI: https://doi.org/10.1124/dmd.109.029488
  12. Bronson, Joanne J.

    1. You have access
      Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation
      Xiaoliang Zhuo, Richard A. Hartz, Joanne J. Bronson, Harvey Wong, Vijay T. Ahuja, Vivekana M. Vrudhula, John E. Leet, Stella Huang, John E. Macor and Yue-Zhong Shu
      Drug Metabolism and Disposition January 2010, 38 (1) 5-15; DOI: https://doi.org/10.1124/dmd.109.028910
  13. Brown, Dean G.

    1. You have access
      Identification of Multiple Glutathione Conjugates of 8-Amino- 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline maleate (Nomifensine) in Liver Microsomes and Hepatocyte Preparations: Evidence of the Bioactivation of Nomifensine
      Jian Yu, Donald E. Mathisen, Doug Burdette, Dean G. Brown, Christopher Becker and David Aharony
      Drug Metabolism and Disposition January 2010, 38 (1) 46-60; DOI: https://doi.org/10.1124/dmd.109.028803
  14. Burdette, Doug

    1. You have access
      Identification of Multiple Glutathione Conjugates of 8-Amino- 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline maleate (Nomifensine) in Liver Microsomes and Hepatocyte Preparations: Evidence of the Bioactivation of Nomifensine
      Jian Yu, Donald E. Mathisen, Doug Burdette, Dean G. Brown, Christopher Becker and David Aharony
      Drug Metabolism and Disposition January 2010, 38 (1) 46-60; DOI: https://doi.org/10.1124/dmd.109.028803

C

  1. Cairns, William

    1. You have access
      Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid
      Bryn M. Owen, Alexandra Milona, Saskia van Mil, Peter Clements, Julie Holder, Mohamed Boudjelal, William Cairns, Malcolm Parker, Roger White and Catherine Williamson
      Drug Metabolism and Disposition January 2010, 38 (1) 143-149; DOI: https://doi.org/10.1124/dmd.109.029306
  2. Castagnoli, Neal

    1. You have access
      Exploration of Catalytic Properties of CYP2D6 and CYP3A4 Through Metabolic Studies of Levorphanol and Levallorphan
      Britta Bonn, Collen M. Masimirembwa and Neal Castagnoli
      Drug Metabolism and Disposition January 2010, 38 (1) 187-199; DOI: https://doi.org/10.1124/dmd.109.028670
  3. Chaponda, Masautso

    1. You have access
      Quantifying the Metabolic Activation of Nevirapine in Patients by Integrated Applications of NMR and Mass Spectrometries
      Abhishek Srivastava, Lu-Yun Lian, James L. Maggs, Masautso Chaponda, Munir Pirmohamed, Dominic P. Williams and B. Kevin Park
      Drug Metabolism and Disposition January 2010, 38 (1) 122-132; DOI: https://doi.org/10.1124/dmd.109.028688
  4. Chen, Hegang

    1. You have access
      Regulation of Gene Expression in Brain Tissues of Rats Repeatedly Treated by the Highly Abused Opioid Agonist, Oxycodone: Microarray Profiling and Gene Mapping Analysis
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Hegang Chen, Andrew Coop and Natalie D. Eddington
      Drug Metabolism and Disposition January 2010, 38 (1) 157-167; DOI: https://doi.org/10.1124/dmd.109.029199
  5. Clements, Peter

    1. You have access
      Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid
      Bryn M. Owen, Alexandra Milona, Saskia van Mil, Peter Clements, Julie Holder, Mohamed Boudjelal, William Cairns, Malcolm Parker, Roger White and Catherine Williamson
      Drug Metabolism and Disposition January 2010, 38 (1) 143-149; DOI: https://doi.org/10.1124/dmd.109.029306
  6. Coop, Andrew

    1. You have access
      Regulation of Gene Expression in Brain Tissues of Rats Repeatedly Treated by the Highly Abused Opioid Agonist, Oxycodone: Microarray Profiling and Gene Mapping Analysis
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Hegang Chen, Andrew Coop and Natalie D. Eddington
      Drug Metabolism and Disposition January 2010, 38 (1) 157-167; DOI: https://doi.org/10.1124/dmd.109.029199

D

  1. Debenham, John S.

    1. You have access
      Glutathione S-Transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine
      Thomas J. Bateman, John S. Debenham, Christina Madsen-Duggan, Richard B. Toupence, Thomas F. Walsh, Quang Truong, Scott A. Bradley, George A. Doss, Sanjeev Kumar and Vijay Bhasker G. Reddy
      Drug Metabolism and Disposition January 2010, 38 (1) 108-114; DOI: https://doi.org/10.1124/dmd.109.029801
  2. Degawa, Masakuni

    1. You have access
      A Possible Mechanism for the Decrease in Serum Thyroxine Level by a 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Like Polychlorinated Biphenyl Congener, 3,3′,4,4′,5-Pentachlorobiphenyl in Mice
      Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa
      Drug Metabolism and Disposition January 2010, 38 (1) 150-156; DOI: https://doi.org/10.1124/dmd.109.029348
  3. Dinchuk, Joseph E.

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637
  4. Doss, George A.

    1. You have access
      Glutathione S-Transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine
      Thomas J. Bateman, John S. Debenham, Christina Madsen-Duggan, Richard B. Toupence, Thomas F. Walsh, Quang Truong, Scott A. Bradley, George A. Doss, Sanjeev Kumar and Vijay Bhasker G. Reddy
      Drug Metabolism and Disposition January 2010, 38 (1) 108-114; DOI: https://doi.org/10.1124/dmd.109.029801
  5. Dulac, Heidi A.

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637

E

  1. Eddington, Natalie D.

    1. You have access
      Regulation of Gene Expression in Brain Tissues of Rats Repeatedly Treated by the Highly Abused Opioid Agonist, Oxycodone: Microarray Profiling and Gene Mapping Analysis
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Hegang Chen, Andrew Coop and Natalie D. Eddington
      Drug Metabolism and Disposition January 2010, 38 (1) 157-167; DOI: https://doi.org/10.1124/dmd.109.029199
  2. Endo, Chihiro

    1. You have access
      Functional Characterization of Mouse Organic Anion Transporting Peptide 1a4 in the Uptake and Efflux of Drugs Across the Blood-Brain Barrier
      Atsushi Ose, Hiroyuki Kusuhara, Chihiro Endo, Kimio Tohyama, Mari Miyajima, Satoshi Kitamura and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2010, 38 (1) 168-176; DOI: https://doi.org/10.1124/dmd.109.029454

F

  1. Farid, Nagy A.

    1. You have access
      Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite
      Miho Kazui, Yumi Nishiya, Tomoko Ishizuka, Katsunobu Hagihara, Nagy A. Farid, Osamu Okazaki, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition January 2010, 38 (1) 92-99; DOI: https://doi.org/10.1124/dmd.109.029132

G

  1. Galinsky, Raymond E.

    1. You have access
      Inhibition of CYP3A by Erythromycin: In Vitro-In Vivo Correlation in Rats
      Xin Zhang, Raymond E. Galinsky, Robert E. Kimura, Sara K. Quinney, David R. Jones and Stephen D. Hall
      Drug Metabolism and Disposition January 2010, 38 (1) 61-72; DOI: https://doi.org/10.1124/dmd.109.028290
  2. Gaulier, Jean-Michel

    1. You have access
      Contribution of the Different UDP-Glucuronosyltransferase (UGT) Isoforms to Buprenorphine and Norbuprenorphine Metabolism and Relationship with the Main UGT Polymorphisms in a Bank of Human Liver Microsomes
      Koukeb Rouguieg, Nicolas Picard, François-Ludovic Sauvage, Jean-Michel Gaulier and Pierre Marquet
      Drug Metabolism and Disposition January 2010, 38 (1) 40-45; DOI: https://doi.org/10.1124/dmd.109.029546
  3. Grace, James E.

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637
  4. Grillo, Mark P.

    1. You have access
      Stereoselective Flunoxaprofen-S-acyl-glutathione Thioester Formation Mediated by Acyl-CoA Formation in Rat Hepatocytes
      Mark P. Grillo, Jill C. M. Wait, Michelle Tadano Lohr, Smriti Khera and Leslie Z. Benet
      Drug Metabolism and Disposition January 2010, 38 (1) 133-142; DOI: https://doi.org/10.1124/dmd.109.029371

H

  1. Hagihara, Katsunobu

    1. You have access
      Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite
      Miho Kazui, Yumi Nishiya, Tomoko Ishizuka, Katsunobu Hagihara, Nagy A. Farid, Osamu Okazaki, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition January 2010, 38 (1) 92-99; DOI: https://doi.org/10.1124/dmd.109.029132
  2. Hall, Stephen D.

    1. You have access
      Inhibition of CYP3A by Erythromycin: In Vitro-In Vivo Correlation in Rats
      Xin Zhang, Raymond E. Galinsky, Robert E. Kimura, Sara K. Quinney, David R. Jones and Stephen D. Hall
      Drug Metabolism and Disposition January 2010, 38 (1) 61-72; DOI: https://doi.org/10.1124/dmd.109.028290
  3. Haraguchi, Koichi

    1. You have access
      A Possible Mechanism for the Decrease in Serum Thyroxine Level by a 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Like Polychlorinated Biphenyl Congener, 3,3′,4,4′,5-Pentachlorobiphenyl in Mice
      Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa
      Drug Metabolism and Disposition January 2010, 38 (1) 150-156; DOI: https://doi.org/10.1124/dmd.109.029348
  4. Hartz, Richard A.

    1. You have access
      Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation
      Xiaoliang Zhuo, Richard A. Hartz, Joanne J. Bronson, Harvey Wong, Vijay T. Ahuja, Vivekana M. Vrudhula, John E. Leet, Stella Huang, John E. Macor and Yue-Zhong Shu
      Drug Metabolism and Disposition January 2010, 38 (1) 5-15; DOI: https://doi.org/10.1124/dmd.109.028910
  5. Hassan, Hazem E.

    1. You have access
      Regulation of Gene Expression in Brain Tissues of Rats Repeatedly Treated by the Highly Abused Opioid Agonist, Oxycodone: Microarray Profiling and Gene Mapping Analysis
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Hegang Chen, Andrew Coop and Natalie D. Eddington
      Drug Metabolism and Disposition January 2010, 38 (1) 157-167; DOI: https://doi.org/10.1124/dmd.109.029199
  6. Helmestam, Malin

    1. You have access
      Tamoxifen-Induced Adduct Formation and Cell Stress in Human Endometrial Glands
      Helén Andersson, Malin Helmestam, Anna Zebrowska, Matts Olovsson and Eva Brittebo
      Drug Metabolism and Disposition January 2010, 38 (1) 200-207; DOI: https://doi.org/10.1124/dmd.109.029488
  7. Holder, Julie

    1. You have access
      Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid
      Bryn M. Owen, Alexandra Milona, Saskia van Mil, Peter Clements, Julie Holder, Mohamed Boudjelal, William Cairns, Malcolm Parker, Roger White and Catherine Williamson
      Drug Metabolism and Disposition January 2010, 38 (1) 143-149; DOI: https://doi.org/10.1124/dmd.109.029306
  8. House, Larry

    1. You have access
      Comparison of the Drug-Drug Interactions Potential of Erlotinib and Gefitinib via Inhibition of UDP-Glucuronosyltransferases
      Yong Liu, Jacqueline Ramírez, Larry House and Mark J. Ratain
      Drug Metabolism and Disposition January 2010, 38 (1) 32-39; DOI: https://doi.org/10.1124/dmd.109.029660
  9. Huang, Stella

    1. You have access
      Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation
      Xiaoliang Zhuo, Richard A. Hartz, Joanne J. Bronson, Harvey Wong, Vijay T. Ahuja, Vivekana M. Vrudhula, John E. Leet, Stella Huang, John E. Macor and Yue-Zhong Shu
      Drug Metabolism and Disposition January 2010, 38 (1) 5-15; DOI: https://doi.org/10.1124/dmd.109.028910

I

  1. Ibrahim, Joseph G.

    1. You have access
      In Vitro Hepatic Metabolism Explains Higher Clearance of Voriconazole in Children versus Adults: Role of CYP2C19 and Flavin-Containing Monooxygenase 3
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Joseph G. Ibrahim, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition January 2010, 38 (1) 25-31; DOI: https://doi.org/10.1124/dmd.109.029769
  2. Ikari, Akira

    1. You have access
      Induction of UGT1A1 and CYP2B6 by an Antimitogenic Factor in HepG2 Cells Is Mediated through Suppression of Cyclin-Dependent Kinase 2 Activity: Cell Cycle-Dependent Expression
      Junko Sugatani, Makoto Osabe, Masatoshi Kurosawa, Naomi Kitamura, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition January 2010, 38 (1) 177-186; DOI: https://doi.org/10.1124/dmd.109.029785
  3. Ikeda, Toshihiko

    1. You have access
      Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite
      Miho Kazui, Yumi Nishiya, Tomoko Ishizuka, Katsunobu Hagihara, Nagy A. Farid, Osamu Okazaki, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition January 2010, 38 (1) 92-99; DOI: https://doi.org/10.1124/dmd.109.029132
  4. Ikushiro, Shin-ichi

    1. You have access
      A Possible Mechanism for the Decrease in Serum Thyroxine Level by a 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Like Polychlorinated Biphenyl Congener, 3,3′,4,4′,5-Pentachlorobiphenyl in Mice
      Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa
      Drug Metabolism and Disposition January 2010, 38 (1) 150-156; DOI: https://doi.org/10.1124/dmd.109.029348
  5. Ishizuka, Tomoko

    1. You have access
      Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite
      Miho Kazui, Yumi Nishiya, Tomoko Ishizuka, Katsunobu Hagihara, Nagy A. Farid, Osamu Okazaki, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition January 2010, 38 (1) 92-99; DOI: https://doi.org/10.1124/dmd.109.029132
  6. Iwai, Megumi

    1. You have access
      Characterization of Human Organic Cation Transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-Mediated Transport of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small Molecule Survivin Suppressant
      Tsuyoshi Minematsu, Megumi Iwai, Ken-ichi Umehara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition January 2010, 38 (1) 1-4; DOI: https://doi.org/10.1124/dmd.109.028142

J

  1. Johansson, Tove

    1. You have access
      In Vitro Metabolism of Haloperidol and Sila-Haloperidol: New Metabolic Pathways Resulting from Carbon/Silicon Exchange
      Tove Johansson, Lars Weidolf, Friedrich Popp, Reinhold Tacke and Ulrik Jurva
      Drug Metabolism and Disposition January 2010, 38 (1) 73-83; DOI: https://doi.org/10.1124/dmd.109.028449
  2. Jones, David R.

    1. You have access
      Inhibition of CYP3A by Erythromycin: In Vitro-In Vivo Correlation in Rats
      Xin Zhang, Raymond E. Galinsky, Robert E. Kimura, Sara K. Quinney, David R. Jones and Stephen D. Hall
      Drug Metabolism and Disposition January 2010, 38 (1) 61-72; DOI: https://doi.org/10.1124/dmd.109.028290
  3. Jurva, Ulrik

    1. You have access
      In Vitro Metabolism of Haloperidol and Sila-Haloperidol: New Metabolic Pathways Resulting from Carbon/Silicon Exchange
      Tove Johansson, Lars Weidolf, Friedrich Popp, Reinhold Tacke and Ulrik Jurva
      Drug Metabolism and Disposition January 2010, 38 (1) 73-83; DOI: https://doi.org/10.1124/dmd.109.028449

K

  1. Kamimura, Hidetaka

    1. You have access
      Characterization of Human Organic Cation Transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-Mediated Transport of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small Molecule Survivin Suppressant
      Tsuyoshi Minematsu, Megumi Iwai, Ken-ichi Umehara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition January 2010, 38 (1) 1-4; DOI: https://doi.org/10.1124/dmd.109.028142
  2. Kato, Yoshihisa

    1. You have access
      A Possible Mechanism for the Decrease in Serum Thyroxine Level by a 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Like Polychlorinated Biphenyl Congener, 3,3′,4,4′,5-Pentachlorobiphenyl in Mice
      Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa
      Drug Metabolism and Disposition January 2010, 38 (1) 150-156; DOI: https://doi.org/10.1124/dmd.109.029348
  3. Kazui, Miho

    1. You have access
      Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite
      Miho Kazui, Yumi Nishiya, Tomoko Ishizuka, Katsunobu Hagihara, Nagy A. Farid, Osamu Okazaki, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition January 2010, 38 (1) 92-99; DOI: https://doi.org/10.1124/dmd.109.029132
  4. Keeney, Diane S.

    1. You have access
      Gene Regulation of CYP4F11 in Human Keratinocyte HaCaT Cells
      Ying Wang, Jordan C. Bell, Diane S. Keeney and Henry W. Strobel
      Drug Metabolism and Disposition January 2010, 38 (1) 100-107; DOI: https://doi.org/10.1124/dmd.109.029025
  5. Kettenberger, Hubert

    1. You have access
      Impact of Molecular Processing in the Hinge Region of Therapeutic IgG4 Antibodies on Disposition Profiles in Cynomolgus Monkeys
      Kay Stubenrauch, Uwe Wessels, Joerg Thomas Regula, Hubert Kettenberger, Julia Schleypen and Ulrich Kohnert
      Drug Metabolism and Disposition January 2010, 38 (1) 84-91; DOI: https://doi.org/10.1124/dmd.109.029751
  6. Khera, Smriti

    1. You have access
      Stereoselective Flunoxaprofen-S-acyl-glutathione Thioester Formation Mediated by Acyl-CoA Formation in Rat Hepatocytes
      Mark P. Grillo, Jill C. M. Wait, Michelle Tadano Lohr, Smriti Khera and Leslie Z. Benet
      Drug Metabolism and Disposition January 2010, 38 (1) 133-142; DOI: https://doi.org/10.1124/dmd.109.029371
  7. Kim, Sean

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637
  8. Kimura, Robert E.

    1. You have access
      Inhibition of CYP3A by Erythromycin: In Vitro-In Vivo Correlation in Rats
      Xin Zhang, Raymond E. Galinsky, Robert E. Kimura, Sara K. Quinney, David R. Jones and Stephen D. Hall
      Drug Metabolism and Disposition January 2010, 38 (1) 61-72; DOI: https://doi.org/10.1124/dmd.109.028290
  9. Kitamura, Naomi

    1. You have access
      Induction of UGT1A1 and CYP2B6 by an Antimitogenic Factor in HepG2 Cells Is Mediated through Suppression of Cyclin-Dependent Kinase 2 Activity: Cell Cycle-Dependent Expression
      Junko Sugatani, Makoto Osabe, Masatoshi Kurosawa, Naomi Kitamura, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition January 2010, 38 (1) 177-186; DOI: https://doi.org/10.1124/dmd.109.029785
  10. Kitamura, Satoshi

    1. You have access
      Functional Characterization of Mouse Organic Anion Transporting Peptide 1a4 in the Uptake and Efflux of Drugs Across the Blood-Brain Barrier
      Atsushi Ose, Hiroyuki Kusuhara, Chihiro Endo, Kimio Tohyama, Mari Miyajima, Satoshi Kitamura and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2010, 38 (1) 168-176; DOI: https://doi.org/10.1124/dmd.109.029454
  11. Koga, Nobuyuki

    1. You have access
      A Possible Mechanism for the Decrease in Serum Thyroxine Level by a 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Like Polychlorinated Biphenyl Congener, 3,3′,4,4′,5-Pentachlorobiphenyl in Mice
      Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa
      Drug Metabolism and Disposition January 2010, 38 (1) 150-156; DOI: https://doi.org/10.1124/dmd.109.029348
  12. Kohnert, Ulrich

    1. You have access
      Impact of Molecular Processing in the Hinge Region of Therapeutic IgG4 Antibodies on Disposition Profiles in Cynomolgus Monkeys
      Kay Stubenrauch, Uwe Wessels, Joerg Thomas Regula, Hubert Kettenberger, Julia Schleypen and Ulrich Kohnert
      Drug Metabolism and Disposition January 2010, 38 (1) 84-91; DOI: https://doi.org/10.1124/dmd.109.029751
  13. Kubota, Makiko

    1. You have access
      A Possible Mechanism for the Decrease in Serum Thyroxine Level by a 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Like Polychlorinated Biphenyl Congener, 3,3′,4,4′,5-Pentachlorobiphenyl in Mice
      Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa
      Drug Metabolism and Disposition January 2010, 38 (1) 150-156; DOI: https://doi.org/10.1124/dmd.109.029348
  14. Kumar, Sanjeev

    1. You have access
      Glutathione S-Transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine
      Thomas J. Bateman, John S. Debenham, Christina Madsen-Duggan, Richard B. Toupence, Thomas F. Walsh, Quang Truong, Scott A. Bradley, George A. Doss, Sanjeev Kumar and Vijay Bhasker G. Reddy
      Drug Metabolism and Disposition January 2010, 38 (1) 108-114; DOI: https://doi.org/10.1124/dmd.109.029801
  15. Kurihara, Atsushi

    1. You have access
      Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite
      Miho Kazui, Yumi Nishiya, Tomoko Ishizuka, Katsunobu Hagihara, Nagy A. Farid, Osamu Okazaki, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition January 2010, 38 (1) 92-99; DOI: https://doi.org/10.1124/dmd.109.029132
  16. Kurosawa, Masatoshi

    1. You have access
      Induction of UGT1A1 and CYP2B6 by an Antimitogenic Factor in HepG2 Cells Is Mediated through Suppression of Cyclin-Dependent Kinase 2 Activity: Cell Cycle-Dependent Expression
      Junko Sugatani, Makoto Osabe, Masatoshi Kurosawa, Naomi Kitamura, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition January 2010, 38 (1) 177-186; DOI: https://doi.org/10.1124/dmd.109.029785
  17. Kusuhara, Hiroyuki

    1. You have access
      Functional Characterization of Mouse Organic Anion Transporting Peptide 1a4 in the Uptake and Efflux of Drugs Across the Blood-Brain Barrier
      Atsushi Ose, Hiroyuki Kusuhara, Chihiro Endo, Kimio Tohyama, Mari Miyajima, Satoshi Kitamura and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2010, 38 (1) 168-176; DOI: https://doi.org/10.1124/dmd.109.029454

L

  1. Lee, Insong J.

    1. You have access
      Regulation of Gene Expression in Brain Tissues of Rats Repeatedly Treated by the Highly Abused Opioid Agonist, Oxycodone: Microarray Profiling and Gene Mapping Analysis
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Hegang Chen, Andrew Coop and Natalie D. Eddington
      Drug Metabolism and Disposition January 2010, 38 (1) 157-167; DOI: https://doi.org/10.1124/dmd.109.029199
  2. Leet, John E.

    1. You have access
      Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation
      Xiaoliang Zhuo, Richard A. Hartz, Joanne J. Bronson, Harvey Wong, Vijay T. Ahuja, Vivekana M. Vrudhula, John E. Leet, Stella Huang, John E. Macor and Yue-Zhong Shu
      Drug Metabolism and Disposition January 2010, 38 (1) 5-15; DOI: https://doi.org/10.1124/dmd.109.028910
  3. Lian, Lu-Yun

    1. You have access
      Quantifying the Metabolic Activation of Nevirapine in Patients by Integrated Applications of NMR and Mass Spectrometries
      Abhishek Srivastava, Lu-Yun Lian, James L. Maggs, Masautso Chaponda, Munir Pirmohamed, Dominic P. Williams and B. Kevin Park
      Drug Metabolism and Disposition January 2010, 38 (1) 122-132; DOI: https://doi.org/10.1124/dmd.109.028688
  4. Lin, Min-Hwa Jasmine

    1. You have access
      Prediction of Vss from In Vitro Tissue-Binding Studies
      Loren M. Berry, Jonathan Roberts, Xuhai Be, Zhiyang Zhao and Min-Hwa Jasmine Lin
      Drug Metabolism and Disposition January 2010, 38 (1) 115-121; DOI: https://doi.org/10.1124/dmd.109.029629
  5. Liu, Yong

    1. You have access
      Comparison of the Drug-Drug Interactions Potential of Erlotinib and Gefitinib via Inhibition of UDP-Glucuronosyltransferases
      Yong Liu, Jacqueline Ramírez, Larry House and Mark J. Ratain
      Drug Metabolism and Disposition January 2010, 38 (1) 32-39; DOI: https://doi.org/10.1124/dmd.109.029660

M

  1. Macor, John E.

    1. You have access
      Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation
      Xiaoliang Zhuo, Richard A. Hartz, Joanne J. Bronson, Harvey Wong, Vijay T. Ahuja, Vivekana M. Vrudhula, John E. Leet, Stella Huang, John E. Macor and Yue-Zhong Shu
      Drug Metabolism and Disposition January 2010, 38 (1) 5-15; DOI: https://doi.org/10.1124/dmd.109.028910
  2. Madsen-Duggan, Christina

    1. You have access
      Glutathione S-Transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine
      Thomas J. Bateman, John S. Debenham, Christina Madsen-Duggan, Richard B. Toupence, Thomas F. Walsh, Quang Truong, Scott A. Bradley, George A. Doss, Sanjeev Kumar and Vijay Bhasker G. Reddy
      Drug Metabolism and Disposition January 2010, 38 (1) 108-114; DOI: https://doi.org/10.1124/dmd.109.029801
  3. Maggs, James L.

    1. You have access
      Quantifying the Metabolic Activation of Nevirapine in Patients by Integrated Applications of NMR and Mass Spectrometries
      Abhishek Srivastava, Lu-Yun Lian, James L. Maggs, Masautso Chaponda, Munir Pirmohamed, Dominic P. Williams and B. Kevin Park
      Drug Metabolism and Disposition January 2010, 38 (1) 122-132; DOI: https://doi.org/10.1124/dmd.109.028688
  4. Marquet, Pierre

    1. You have access
      Contribution of the Different UDP-Glucuronosyltransferase (UGT) Isoforms to Buprenorphine and Norbuprenorphine Metabolism and Relationship with the Main UGT Polymorphisms in a Bank of Human Liver Microsomes
      Koukeb Rouguieg, Nicolas Picard, François-Ludovic Sauvage, Jean-Michel Gaulier and Pierre Marquet
      Drug Metabolism and Disposition January 2010, 38 (1) 40-45; DOI: https://doi.org/10.1124/dmd.109.029546
  5. Masimirembwa, Collen M.

    1. You have access
      Exploration of Catalytic Properties of CYP2D6 and CYP3A4 Through Metabolic Studies of Levorphanol and Levallorphan
      Britta Bonn, Collen M. Masimirembwa and Neal Castagnoli
      Drug Metabolism and Disposition January 2010, 38 (1) 187-199; DOI: https://doi.org/10.1124/dmd.109.028670
  6. Mathisen, Donald E.

    1. You have access
      Identification of Multiple Glutathione Conjugates of 8-Amino- 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline maleate (Nomifensine) in Liver Microsomes and Hepatocyte Preparations: Evidence of the Bioactivation of Nomifensine
      Jian Yu, Donald E. Mathisen, Doug Burdette, Dean G. Brown, Christopher Becker and David Aharony
      Drug Metabolism and Disposition January 2010, 38 (1) 46-60; DOI: https://doi.org/10.1124/dmd.109.028803
  7. Milona, Alexandra

    1. You have access
      Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid
      Bryn M. Owen, Alexandra Milona, Saskia van Mil, Peter Clements, Julie Holder, Mohamed Boudjelal, William Cairns, Malcolm Parker, Roger White and Catherine Williamson
      Drug Metabolism and Disposition January 2010, 38 (1) 143-149; DOI: https://doi.org/10.1124/dmd.109.029306
  8. Minematsu, Tsuyoshi

    1. You have access
      Characterization of Human Organic Cation Transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-Mediated Transport of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small Molecule Survivin Suppressant
      Tsuyoshi Minematsu, Megumi Iwai, Ken-ichi Umehara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition January 2010, 38 (1) 1-4; DOI: https://doi.org/10.1124/dmd.109.028142
  9. Miwa, Masao

    1. You have access
      Induction of UGT1A1 and CYP2B6 by an Antimitogenic Factor in HepG2 Cells Is Mediated through Suppression of Cyclin-Dependent Kinase 2 Activity: Cell Cycle-Dependent Expression
      Junko Sugatani, Makoto Osabe, Masatoshi Kurosawa, Naomi Kitamura, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition January 2010, 38 (1) 177-186; DOI: https://doi.org/10.1124/dmd.109.029785
  10. Miyajima, Mari

    1. You have access
      Functional Characterization of Mouse Organic Anion Transporting Peptide 1a4 in the Uptake and Efflux of Drugs Across the Blood-Brain Barrier
      Atsushi Ose, Hiroyuki Kusuhara, Chihiro Endo, Kimio Tohyama, Mari Miyajima, Satoshi Kitamura and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2010, 38 (1) 168-176; DOI: https://doi.org/10.1124/dmd.109.029454
  11. Mosure, Kathleen W.

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637
  12. Myers, Alan L.

    1. You have access
      Regulation of Gene Expression in Brain Tissues of Rats Repeatedly Treated by the Highly Abused Opioid Agonist, Oxycodone: Microarray Profiling and Gene Mapping Analysis
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Hegang Chen, Andrew Coop and Natalie D. Eddington
      Drug Metabolism and Disposition January 2010, 38 (1) 157-167; DOI: https://doi.org/10.1124/dmd.109.029199

N

  1. Nishiya, Yumi

    1. You have access
      Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite
      Miho Kazui, Yumi Nishiya, Tomoko Ishizuka, Katsunobu Hagihara, Nagy A. Farid, Osamu Okazaki, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition January 2010, 38 (1) 92-99; DOI: https://doi.org/10.1124/dmd.109.029132

O

  1. Okazaki, Osamu

    1. You have access
      Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite
      Miho Kazui, Yumi Nishiya, Tomoko Ishizuka, Katsunobu Hagihara, Nagy A. Farid, Osamu Okazaki, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition January 2010, 38 (1) 92-99; DOI: https://doi.org/10.1124/dmd.109.029132
  2. Okura, Takashi

    1. You have access
      A Possible Mechanism for the Decrease in Serum Thyroxine Level by a 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Like Polychlorinated Biphenyl Congener, 3,3′,4,4′,5-Pentachlorobiphenyl in Mice
      Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa
      Drug Metabolism and Disposition January 2010, 38 (1) 150-156; DOI: https://doi.org/10.1124/dmd.109.029348
  3. Olovsson, Matts

    1. You have access
      Tamoxifen-Induced Adduct Formation and Cell Stress in Human Endometrial Glands
      Helén Andersson, Malin Helmestam, Anna Zebrowska, Matts Olovsson and Eva Brittebo
      Drug Metabolism and Disposition January 2010, 38 (1) 200-207; DOI: https://doi.org/10.1124/dmd.109.029488
  4. Orcutt, Tami

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637
  5. Osabe, Makoto

    1. You have access
      Induction of UGT1A1 and CYP2B6 by an Antimitogenic Factor in HepG2 Cells Is Mediated through Suppression of Cyclin-Dependent Kinase 2 Activity: Cell Cycle-Dependent Expression
      Junko Sugatani, Makoto Osabe, Masatoshi Kurosawa, Naomi Kitamura, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition January 2010, 38 (1) 177-186; DOI: https://doi.org/10.1124/dmd.109.029785
  6. Ose, Atsushi

    1. You have access
      Functional Characterization of Mouse Organic Anion Transporting Peptide 1a4 in the Uptake and Efflux of Drugs Across the Blood-Brain Barrier
      Atsushi Ose, Hiroyuki Kusuhara, Chihiro Endo, Kimio Tohyama, Mari Miyajima, Satoshi Kitamura and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2010, 38 (1) 168-176; DOI: https://doi.org/10.1124/dmd.109.029454
  7. Owen, Bryn M.

    1. You have access
      Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid
      Bryn M. Owen, Alexandra Milona, Saskia van Mil, Peter Clements, Julie Holder, Mohamed Boudjelal, William Cairns, Malcolm Parker, Roger White and Catherine Williamson
      Drug Metabolism and Disposition January 2010, 38 (1) 143-149; DOI: https://doi.org/10.1124/dmd.109.029306

P

  1. Park, B. Kevin

    1. You have access
      Quantifying the Metabolic Activation of Nevirapine in Patients by Integrated Applications of NMR and Mass Spectrometries
      Abhishek Srivastava, Lu-Yun Lian, James L. Maggs, Masautso Chaponda, Munir Pirmohamed, Dominic P. Williams and B. Kevin Park
      Drug Metabolism and Disposition January 2010, 38 (1) 122-132; DOI: https://doi.org/10.1124/dmd.109.028688
  2. Parker, Malcolm

    1. You have access
      Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid
      Bryn M. Owen, Alexandra Milona, Saskia van Mil, Peter Clements, Julie Holder, Mohamed Boudjelal, William Cairns, Malcolm Parker, Roger White and Catherine Williamson
      Drug Metabolism and Disposition January 2010, 38 (1) 143-149; DOI: https://doi.org/10.1124/dmd.109.029306
  3. Picard, Nicolas

    1. You have access
      Contribution of the Different UDP-Glucuronosyltransferase (UGT) Isoforms to Buprenorphine and Norbuprenorphine Metabolism and Relationship with the Main UGT Polymorphisms in a Bank of Human Liver Microsomes
      Koukeb Rouguieg, Nicolas Picard, François-Ludovic Sauvage, Jean-Michel Gaulier and Pierre Marquet
      Drug Metabolism and Disposition January 2010, 38 (1) 40-45; DOI: https://doi.org/10.1124/dmd.109.029546
  4. Pirmohamed, Munir

    1. You have access
      Quantifying the Metabolic Activation of Nevirapine in Patients by Integrated Applications of NMR and Mass Spectrometries
      Abhishek Srivastava, Lu-Yun Lian, James L. Maggs, Masautso Chaponda, Munir Pirmohamed, Dominic P. Williams and B. Kevin Park
      Drug Metabolism and Disposition January 2010, 38 (1) 122-132; DOI: https://doi.org/10.1124/dmd.109.028688
  5. Pizzano, Jennifer

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637
  6. Popp, Friedrich

    1. You have access
      In Vitro Metabolism of Haloperidol and Sila-Haloperidol: New Metabolic Pathways Resulting from Carbon/Silicon Exchange
      Tove Johansson, Lars Weidolf, Friedrich Popp, Reinhold Tacke and Ulrik Jurva
      Drug Metabolism and Disposition January 2010, 38 (1) 73-83; DOI: https://doi.org/10.1124/dmd.109.028449

Q

  1. Quinney, Sara K.

    1. You have access
      Inhibition of CYP3A by Erythromycin: In Vitro-In Vivo Correlation in Rats
      Xin Zhang, Raymond E. Galinsky, Robert E. Kimura, Sara K. Quinney, David R. Jones and Stephen D. Hall
      Drug Metabolism and Disposition January 2010, 38 (1) 61-72; DOI: https://doi.org/10.1124/dmd.109.028290

R

  1. Ramírez, Jacqueline

    1. You have access
      Comparison of the Drug-Drug Interactions Potential of Erlotinib and Gefitinib via Inhibition of UDP-Glucuronosyltransferases
      Yong Liu, Jacqueline Ramírez, Larry House and Mark J. Ratain
      Drug Metabolism and Disposition January 2010, 38 (1) 32-39; DOI: https://doi.org/10.1124/dmd.109.029660
  2. Ratain, Mark J.

    1. You have access
      Comparison of the Drug-Drug Interactions Potential of Erlotinib and Gefitinib via Inhibition of UDP-Glucuronosyltransferases
      Yong Liu, Jacqueline Ramírez, Larry House and Mark J. Ratain
      Drug Metabolism and Disposition January 2010, 38 (1) 32-39; DOI: https://doi.org/10.1124/dmd.109.029660
  3. Reddy, Vijay Bhasker G.

    1. You have access
      Glutathione S-Transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine
      Thomas J. Bateman, John S. Debenham, Christina Madsen-Duggan, Richard B. Toupence, Thomas F. Walsh, Quang Truong, Scott A. Bradley, George A. Doss, Sanjeev Kumar and Vijay Bhasker G. Reddy
      Drug Metabolism and Disposition January 2010, 38 (1) 108-114; DOI: https://doi.org/10.1124/dmd.109.029801
  4. Regula, Joerg Thomas

    1. You have access
      Impact of Molecular Processing in the Hinge Region of Therapeutic IgG4 Antibodies on Disposition Profiles in Cynomolgus Monkeys
      Kay Stubenrauch, Uwe Wessels, Joerg Thomas Regula, Hubert Kettenberger, Julia Schleypen and Ulrich Kohnert
      Drug Metabolism and Disposition January 2010, 38 (1) 84-91; DOI: https://doi.org/10.1124/dmd.109.029751
  5. Roberts, Jonathan

    1. You have access
      Prediction of Vss from In Vitro Tissue-Binding Studies
      Loren M. Berry, Jonathan Roberts, Xuhai Be, Zhiyang Zhao and Min-Hwa Jasmine Lin
      Drug Metabolism and Disposition January 2010, 38 (1) 115-121; DOI: https://doi.org/10.1124/dmd.109.029629
  6. Rouguieg, Koukeb

    1. You have access
      Contribution of the Different UDP-Glucuronosyltransferase (UGT) Isoforms to Buprenorphine and Norbuprenorphine Metabolism and Relationship with the Main UGT Polymorphisms in a Bank of Human Liver Microsomes
      Koukeb Rouguieg, Nicolas Picard, François-Ludovic Sauvage, Jean-Michel Gaulier and Pierre Marquet
      Drug Metabolism and Disposition January 2010, 38 (1) 40-45; DOI: https://doi.org/10.1124/dmd.109.029546

S

  1. Sauer, Mary B.

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637
  2. Sauvage, François-Ludovic

    1. You have access
      Contribution of the Different UDP-Glucuronosyltransferase (UGT) Isoforms to Buprenorphine and Norbuprenorphine Metabolism and Relationship with the Main UGT Polymorphisms in a Bank of Human Liver Microsomes
      Koukeb Rouguieg, Nicolas Picard, François-Ludovic Sauvage, Jean-Michel Gaulier and Pierre Marquet
      Drug Metabolism and Disposition January 2010, 38 (1) 40-45; DOI: https://doi.org/10.1124/dmd.109.029546
  3. Schleypen, Julia

    1. You have access
      Impact of Molecular Processing in the Hinge Region of Therapeutic IgG4 Antibodies on Disposition Profiles in Cynomolgus Monkeys
      Kay Stubenrauch, Uwe Wessels, Joerg Thomas Regula, Hubert Kettenberger, Julia Schleypen and Ulrich Kohnert
      Drug Metabolism and Disposition January 2010, 38 (1) 84-91; DOI: https://doi.org/10.1124/dmd.109.029751
  4. Seto, Yoshiki

    1. You have access
      A Possible Mechanism for the Decrease in Serum Thyroxine Level by a 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Like Polychlorinated Biphenyl Congener, 3,3′,4,4′,5-Pentachlorobiphenyl in Mice
      Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa
      Drug Metabolism and Disposition January 2010, 38 (1) 150-156; DOI: https://doi.org/10.1124/dmd.109.029348
  5. Shu, Yue-Zhong

    1. You have access
      Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation
      Xiaoliang Zhuo, Richard A. Hartz, Joanne J. Bronson, Harvey Wong, Vijay T. Ahuja, Vivekana M. Vrudhula, John E. Leet, Stella Huang, John E. Macor and Yue-Zhong Shu
      Drug Metabolism and Disposition January 2010, 38 (1) 5-15; DOI: https://doi.org/10.1124/dmd.109.028910
  6. Simmermacher, Jean

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637
  7. Sinz, Michael

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637
  8. Srivastava, Abhishek

    1. You have access
      Quantifying the Metabolic Activation of Nevirapine in Patients by Integrated Applications of NMR and Mass Spectrometries
      Abhishek Srivastava, Lu-Yun Lian, James L. Maggs, Masautso Chaponda, Munir Pirmohamed, Dominic P. Williams and B. Kevin Park
      Drug Metabolism and Disposition January 2010, 38 (1) 122-132; DOI: https://doi.org/10.1124/dmd.109.028688
  9. Strobel, Henry W.

    1. You have access
      Gene Regulation of CYP4F11 in Human Keratinocyte HaCaT Cells
      Ying Wang, Jordan C. Bell, Diane S. Keeney and Henry W. Strobel
      Drug Metabolism and Disposition January 2010, 38 (1) 100-107; DOI: https://doi.org/10.1124/dmd.109.029025
  10. Stubenrauch, Kay

    1. You have access
      Impact of Molecular Processing in the Hinge Region of Therapeutic IgG4 Antibodies on Disposition Profiles in Cynomolgus Monkeys
      Kay Stubenrauch, Uwe Wessels, Joerg Thomas Regula, Hubert Kettenberger, Julia Schleypen and Ulrich Kohnert
      Drug Metabolism and Disposition January 2010, 38 (1) 84-91; DOI: https://doi.org/10.1124/dmd.109.029751
  11. Sugatani, Junko

    1. You have access
      Induction of UGT1A1 and CYP2B6 by an Antimitogenic Factor in HepG2 Cells Is Mediated through Suppression of Cyclin-Dependent Kinase 2 Activity: Cell Cycle-Dependent Expression
      Junko Sugatani, Makoto Osabe, Masatoshi Kurosawa, Naomi Kitamura, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition January 2010, 38 (1) 177-186; DOI: https://doi.org/10.1124/dmd.109.029785
  12. Sugiyama, Yuichi

    1. You have access
      Functional Characterization of Mouse Organic Anion Transporting Peptide 1a4 in the Uptake and Efflux of Drugs Across the Blood-Brain Barrier
      Atsushi Ose, Hiroyuki Kusuhara, Chihiro Endo, Kimio Tohyama, Mari Miyajima, Satoshi Kitamura and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2010, 38 (1) 168-176; DOI: https://doi.org/10.1124/dmd.109.029454

T

  1. Tacke, Reinhold

    1. You have access
      In Vitro Metabolism of Haloperidol and Sila-Haloperidol: New Metabolic Pathways Resulting from Carbon/Silicon Exchange
      Tove Johansson, Lars Weidolf, Friedrich Popp, Reinhold Tacke and Ulrik Jurva
      Drug Metabolism and Disposition January 2010, 38 (1) 73-83; DOI: https://doi.org/10.1124/dmd.109.028449
  2. Tadano Lohr, Michelle

    1. You have access
      Stereoselective Flunoxaprofen-S-acyl-glutathione Thioester Formation Mediated by Acyl-CoA Formation in Rat Hepatocytes
      Mark P. Grillo, Jill C. M. Wait, Michelle Tadano Lohr, Smriti Khera and Leslie Z. Benet
      Drug Metabolism and Disposition January 2010, 38 (1) 133-142; DOI: https://doi.org/10.1124/dmd.109.029371
  3. Thakker, Dhiren R.

    1. You have access
      In Vitro Hepatic Metabolism Explains Higher Clearance of Voriconazole in Children versus Adults: Role of CYP2C19 and Flavin-Containing Monooxygenase 3
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Joseph G. Ibrahim, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition January 2010, 38 (1) 25-31; DOI: https://doi.org/10.1124/dmd.109.029769
  4. Tohyama, Kimio

    1. You have access
      Functional Characterization of Mouse Organic Anion Transporting Peptide 1a4 in the Uptake and Efflux of Drugs Across the Blood-Brain Barrier
      Atsushi Ose, Hiroyuki Kusuhara, Chihiro Endo, Kimio Tohyama, Mari Miyajima, Satoshi Kitamura and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2010, 38 (1) 168-176; DOI: https://doi.org/10.1124/dmd.109.029454
  5. Toupence, Richard B.

    1. You have access
      Glutathione S-Transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine
      Thomas J. Bateman, John S. Debenham, Christina Madsen-Duggan, Richard B. Toupence, Thomas F. Walsh, Quang Truong, Scott A. Bradley, George A. Doss, Sanjeev Kumar and Vijay Bhasker G. Reddy
      Drug Metabolism and Disposition January 2010, 38 (1) 108-114; DOI: https://doi.org/10.1124/dmd.109.029801
  6. Truong, Quang

    1. You have access
      Glutathione S-Transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine
      Thomas J. Bateman, John S. Debenham, Christina Madsen-Duggan, Richard B. Toupence, Thomas F. Walsh, Quang Truong, Scott A. Bradley, George A. Doss, Sanjeev Kumar and Vijay Bhasker G. Reddy
      Drug Metabolism and Disposition January 2010, 38 (1) 108-114; DOI: https://doi.org/10.1124/dmd.109.029801

U

  1. Umehara, Ken-ichi

    1. You have access
      Characterization of Human Organic Cation Transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-Mediated Transport of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small Molecule Survivin Suppressant
      Tsuyoshi Minematsu, Megumi Iwai, Ken-ichi Umehara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition January 2010, 38 (1) 1-4; DOI: https://doi.org/10.1124/dmd.109.028142
  2. Usui, Takashi

    1. You have access
      Characterization of Human Organic Cation Transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-Mediated Transport of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small Molecule Survivin Suppressant
      Tsuyoshi Minematsu, Megumi Iwai, Ken-ichi Umehara, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition January 2010, 38 (1) 1-4; DOI: https://doi.org/10.1124/dmd.109.028142

V

  1. van Mil, Saskia

    1. You have access
      Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid
      Bryn M. Owen, Alexandra Milona, Saskia van Mil, Peter Clements, Julie Holder, Mohamed Boudjelal, William Cairns, Malcolm Parker, Roger White and Catherine Williamson
      Drug Metabolism and Disposition January 2010, 38 (1) 143-149; DOI: https://doi.org/10.1124/dmd.109.029306
  2. Vrudhula, Vivekana M.

    1. You have access
      Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation
      Xiaoliang Zhuo, Richard A. Hartz, Joanne J. Bronson, Harvey Wong, Vijay T. Ahuja, Vivekana M. Vrudhula, John E. Leet, Stella Huang, John E. Macor and Yue-Zhong Shu
      Drug Metabolism and Disposition January 2010, 38 (1) 5-15; DOI: https://doi.org/10.1124/dmd.109.028910
  3. Vuppugalla, Ragini

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637

W

  1. Wait, Jill C. M.

    1. You have access
      Stereoselective Flunoxaprofen-S-acyl-glutathione Thioester Formation Mediated by Acyl-CoA Formation in Rat Hepatocytes
      Mark P. Grillo, Jill C. M. Wait, Michelle Tadano Lohr, Smriti Khera and Leslie Z. Benet
      Drug Metabolism and Disposition January 2010, 38 (1) 133-142; DOI: https://doi.org/10.1124/dmd.109.029371
  2. Walsh, Thomas F.

    1. You have access
      Glutathione S-Transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine
      Thomas J. Bateman, John S. Debenham, Christina Madsen-Duggan, Richard B. Toupence, Thomas F. Walsh, Quang Truong, Scott A. Bradley, George A. Doss, Sanjeev Kumar and Vijay Bhasker G. Reddy
      Drug Metabolism and Disposition January 2010, 38 (1) 108-114; DOI: https://doi.org/10.1124/dmd.109.029801
  3. Wang, Ying

    1. You have access
      Gene Regulation of CYP4F11 in Human Keratinocyte HaCaT Cells
      Ying Wang, Jordan C. Bell, Diane S. Keeney and Henry W. Strobel
      Drug Metabolism and Disposition January 2010, 38 (1) 100-107; DOI: https://doi.org/10.1124/dmd.109.029025
  4. Weidolf, Lars

    1. You have access
      In Vitro Metabolism of Haloperidol and Sila-Haloperidol: New Metabolic Pathways Resulting from Carbon/Silicon Exchange
      Tove Johansson, Lars Weidolf, Friedrich Popp, Reinhold Tacke and Ulrik Jurva
      Drug Metabolism and Disposition January 2010, 38 (1) 73-83; DOI: https://doi.org/10.1124/dmd.109.028449
  5. Wessels, Uwe

    1. You have access
      Impact of Molecular Processing in the Hinge Region of Therapeutic IgG4 Antibodies on Disposition Profiles in Cynomolgus Monkeys
      Kay Stubenrauch, Uwe Wessels, Joerg Thomas Regula, Hubert Kettenberger, Julia Schleypen and Ulrich Kohnert
      Drug Metabolism and Disposition January 2010, 38 (1) 84-91; DOI: https://doi.org/10.1124/dmd.109.029751
  6. White, Roger

    1. You have access
      Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid
      Bryn M. Owen, Alexandra Milona, Saskia van Mil, Peter Clements, Julie Holder, Mohamed Boudjelal, William Cairns, Malcolm Parker, Roger White and Catherine Williamson
      Drug Metabolism and Disposition January 2010, 38 (1) 143-149; DOI: https://doi.org/10.1124/dmd.109.029306
  7. Williams, Dominic P.

    1. You have access
      Quantifying the Metabolic Activation of Nevirapine in Patients by Integrated Applications of NMR and Mass Spectrometries
      Abhishek Srivastava, Lu-Yun Lian, James L. Maggs, Masautso Chaponda, Munir Pirmohamed, Dominic P. Williams and B. Kevin Park
      Drug Metabolism and Disposition January 2010, 38 (1) 122-132; DOI: https://doi.org/10.1124/dmd.109.028688
  8. Williamson, Catherine

    1. You have access
      Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid
      Bryn M. Owen, Alexandra Milona, Saskia van Mil, Peter Clements, Julie Holder, Mohamed Boudjelal, William Cairns, Malcolm Parker, Roger White and Catherine Williamson
      Drug Metabolism and Disposition January 2010, 38 (1) 143-149; DOI: https://doi.org/10.1124/dmd.109.029306
  9. Wong, Harvey

    1. You have access
      Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation
      Xiaoliang Zhuo, Richard A. Hartz, Joanne J. Bronson, Harvey Wong, Vijay T. Ahuja, Vivekana M. Vrudhula, John E. Leet, Stella Huang, John E. Macor and Yue-Zhong Shu
      Drug Metabolism and Disposition January 2010, 38 (1) 5-15; DOI: https://doi.org/10.1124/dmd.109.028910

Y

  1. Yamada, Shizuo

    1. You have access
      A Possible Mechanism for the Decrease in Serum Thyroxine Level by a 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Like Polychlorinated Biphenyl Congener, 3,3′,4,4′,5-Pentachlorobiphenyl in Mice
      Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa
      Drug Metabolism and Disposition January 2010, 38 (1) 150-156; DOI: https://doi.org/10.1124/dmd.109.029348
  2. Yanni, Souzan B.

    1. You have access
      In Vitro Hepatic Metabolism Explains Higher Clearance of Voriconazole in Children versus Adults: Role of CYP2C19 and Flavin-Containing Monooxygenase 3
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Joseph G. Ibrahim, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition January 2010, 38 (1) 25-31; DOI: https://doi.org/10.1124/dmd.109.029769
  3. Yu, Jian

    1. You have access
      Identification of Multiple Glutathione Conjugates of 8-Amino- 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline maleate (Nomifensine) in Liver Microsomes and Hepatocyte Preparations: Evidence of the Bioactivation of Nomifensine
      Jian Yu, Donald E. Mathisen, Doug Burdette, Dean G. Brown, Christopher Becker and David Aharony
      Drug Metabolism and Disposition January 2010, 38 (1) 46-60; DOI: https://doi.org/10.1124/dmd.109.028803

Z

  1. Zebrowska, Anna

    1. You have access
      Tamoxifen-Induced Adduct Formation and Cell Stress in Human Endometrial Glands
      Helén Andersson, Malin Helmestam, Anna Zebrowska, Matts Olovsson and Eva Brittebo
      Drug Metabolism and Disposition January 2010, 38 (1) 200-207; DOI: https://doi.org/10.1124/dmd.109.029488
  2. Zhang, Xin

    1. You have access
      Inhibition of CYP3A by Erythromycin: In Vitro-In Vivo Correlation in Rats
      Xin Zhang, Raymond E. Galinsky, Robert E. Kimura, Sara K. Quinney, David R. Jones and Stephen D. Hall
      Drug Metabolism and Disposition January 2010, 38 (1) 61-72; DOI: https://doi.org/10.1124/dmd.109.028290
  3. Zhao, Zhiyang

    1. You have access
      Prediction of Vss from In Vitro Tissue-Binding Studies
      Loren M. Berry, Jonathan Roberts, Xuhai Be, Zhiyang Zhao and Min-Hwa Jasmine Lin
      Drug Metabolism and Disposition January 2010, 38 (1) 115-121; DOI: https://doi.org/10.1124/dmd.109.029629
  4. Zhuo, Xiaoliang

    1. You have access
      Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation
      Xiaoliang Zhuo, Richard A. Hartz, Joanne J. Bronson, Harvey Wong, Vijay T. Ahuja, Vivekana M. Vrudhula, John E. Leet, Stella Huang, John E. Macor and Yue-Zhong Shu
      Drug Metabolism and Disposition January 2010, 38 (1) 5-15; DOI: https://doi.org/10.1124/dmd.109.028910
  5. Zoeckler, Mary E.

    1. You have access
      Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
      Sean Kim, Joseph E. Dinchuk, Monique N. Anthony, Tami Orcutt, Mary E. Zoeckler, Mary B. Sauer, Kathleen W. Mosure, Ragini Vuppugalla, James E. Grace, Jean Simmermacher, Heidi A. Dulac, Jennifer Pizzano and Michael Sinz
      Drug Metabolism and Disposition January 2010, 38 (1) 16-24; DOI: https://doi.org/10.1124/dmd.109.029637
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Drug Metabolism and Disposition: 38 (1)
Drug Metabolism and Disposition
Vol. 38, Issue 1
1 Jan 2010
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