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History
- Received May 7, 2010
- Accepted July 15, 2010
- Published online September 20, 2010.
Article Versions
- Earlier version (July 15, 2010 - 13:59).
- You are viewing the most recent version of this article.
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U.S. Government work not protected by U.S. copyright
Author Information
- Clinical Center Pharmacy Department (Y.Y.H.), and National Heart, Lung, and Blood Institute Vascular Medicine Branch (A.D., M.T.G.), National Institutes of Health, Bethesda, Maryland; and School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, People's Republic of China (H.S.)
- Address correspondence to:
Dr. Christine Yuen-Yi Hon, Clinical Pharmacokinetic Research Laboratory, Clinical Center Pharmacy Department, National Institutes of Health, Bldg. 10, Rm. 1C240, 10 Center Drive, Bethesda, MD 20892. E-mail: chon{at}cc.nih.gov
Parts of this work were previously presented at the following conference: Hon YY, Sun H, Dejam A, and Gladwin MT (2009) A physiological pharmacokinetic model (PPKM) characterizes the in vivo metabolic and disposition pathways of nitrite (NO2−), nitrate (NO3−), methemoglobin (MetHb), and iron nitrosylhemoglobin (NOHb). American Society for Clinical Pharmacology and Therapeutics 110th Annual Meeting; 2009 Mar 18–21; National Harbor, MD. Clin Pharmacol Ther 85 (Suppl 1): S35. American Society for Clinical Pharmacology and Therapeutics, Alexandria, VA.