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Research ArticleArticle

Alternatively Spliced Products of the UGT1A Gene Interact with the Enzymatically Active Proteins to Inhibit Glucuronosyltransferase Activity In Vitro

Judith Bellemare, Mélanie Rouleau, Hugo Girard, Mario Harvey and Chantal Guillemette
Drug Metabolism and Disposition October 2010, 38 (10) 1785-1789; DOI: https://doi.org/10.1124/dmd.110.034835
Judith Bellemare
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Mélanie Rouleau
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Hugo Girard
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Mario Harvey
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Chantal Guillemette
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Article Information

vol. 38 no. 10 1785-1789
DOI 
https://doi.org/10.1124/dmd.110.034835
PubMed 
20610558

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 4, 2010
  • Accepted July 7, 2010
  • Published online September 20, 2010.

Article Versions

  • Earlier version (July 7, 2010 - 12:17).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Judith Bellemare,
  2. Mélanie Rouleau,
  3. Hugo Girard,
  4. Mario Harvey and
  5. Chantal Guillemette
  1. Pharmacogenomics Laboratory (J.B., M.R., H.G., M.H., C.G.) and Canada Research Chair in Pharmacogenomics (C.G.), Centre Hospitalier de l'Université Laval Research Center and Faculty of Pharmacy, Laval University, Québec, Canada
  1. Address correspondence to:
    Dr. Chantal Guillemette, Pharmacogenomics Laboratory CHUQ Research Center 2705, Boul. Laurier, T3-48, Québec, QC G1V 4G2, QC, Canada. E-mail: chantal.guillemette{at}crchul.ulaval.ca
  1. Parts of this work were previously presented as follows: Bellemare J, Rouleau M, and Guillemette C (2009) Function co-expression of UGT1 alternatively spliced isoforms and evidence of protein-protein interaction. 11th European ISSX Meeting; 2009 May 17–20; Lisbon, Portugal. The International Society for the Study of Xenobiotics, Washington, DC.

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Drug Metabolism and Disposition: 38 (10)
Drug Metabolism and Disposition
Vol. 38, Issue 10
1 Oct 2010
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Research ArticleArticle

Alternatively Spliced Products of the UGT1A Gene Interact with the Enzymatically Active Proteins to Inhibit Glucuronosyltransferase Activity In Vitro

Judith Bellemare, Mélanie Rouleau, Hugo Girard, Mario Harvey and Chantal Guillemette
Drug Metabolism and Disposition October 1, 2010, 38 (10) 1785-1789; DOI: https://doi.org/10.1124/dmd.110.034835

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Research ArticleArticle

Alternatively Spliced Products of the UGT1A Gene Interact with the Enzymatically Active Proteins to Inhibit Glucuronosyltransferase Activity In Vitro

Judith Bellemare, Mélanie Rouleau, Hugo Girard, Mario Harvey and Chantal Guillemette
Drug Metabolism and Disposition October 1, 2010, 38 (10) 1785-1789; DOI: https://doi.org/10.1124/dmd.110.034835
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