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Assessment of a Micropatterned Hepatocyte Coculture System to Generate Major Human Excretory and Circulating Drug Metabolites

Wendy WeiWei Wang, Salman R. Khetani, Stacy Krzyzewski, David B. Duignan and R. Scott Obach
Drug Metabolism and Disposition October 2010, 38 (10) 1900-1905; DOI: https://doi.org/10.1124/dmd.110.034876

Article Information

vol. 38 no. 10 1900-1905
DOI 
https://doi.org/10.1124/dmd.110.034876
PubMed 
20595376
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 7, 2010
  • Accepted July 1, 2010
  • Published online September 20, 2010.

Article Versions

Copyright & Usage 
Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Wendy WeiWei Wang,
  2. Salman R. Khetani,
  3. Stacy Krzyzewski,
  4. David B. Duignan and
  5. R. Scott Obach
  1. Pfizer Global Research and Development, Groton, Connecticut (W.W.W., D.B.D., R.S.O.); and Hepregen Corporation, Medford, Massachusetts (S.R.K., S.K.)
  1. Address correspondence to:
    R. S. Obach, Pfizer, Inc., Eastern Point Rd., Groton, CT 06340. E-mail: r.scott.obach{at}pfizer.com
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Rapid CommunicationAccelerated Communication

Assessment of a Micropatterned Hepatocyte Coculture System to Generate Major Human Excretory and Circulating Drug Metabolites

Wendy WeiWei Wang, Salman R. Khetani, Stacy Krzyzewski, David B. Duignan and R. Scott Obach
Drug Metabolism and Disposition October 1, 2010, 38 (10) 1900-1905; DOI: https://doi.org/10.1124/dmd.110.034876
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