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Research ArticleArticle

Prediction of Efficacious Inhalation Lung Doses via the Use of In Silico Lung Retention Quantitative Structure-Activity Relationship Models and In Vitro Potency Screens

Anne Cooper, Tim Potter and Tim Luker
Drug Metabolism and Disposition December 2010, 38 (12) 2218-2225; DOI: https://doi.org/10.1124/dmd.110.034462

Article Information

vol. 38 no. 12 2218-2225
DOI 
https://doi.org/10.1124/dmd.110.034462
PubMed 
20823295
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 14, 2010
  • Accepted September 7, 2010
  • Published online November 17, 2010.

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Copyright & Usage 
Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Anne Cooper,
  2. Tim Potter and
  3. Tim Luker
  1. AstraZeneca R&D Charnwood, Loughborough, Leicestershire, United Kingdom
  1. Address correspondence to:
    Dr. Anne E. Cooper, Discovery DMPK, AstraZeneca R&D Charnwood, Bakewell Rd., Loughborough, Leicestershire, UK LE11 5RH. E-mail: anne.cooper{at}astrazeneca.com
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Research ArticleArticle

Prediction of Efficacious Inhalation Lung Doses via the Use of In Silico Lung Retention Quantitative Structure-Activity Relationship Models and In Vitro Potency Screens

Anne Cooper, Tim Potter and Tim Luker
Drug Metabolism and Disposition December 1, 2010, 38 (12) 2218-2225; DOI: https://doi.org/10.1124/dmd.110.034462
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