Index by author
February 01, 2010; Volume 38,Issue 2
A
Acharya, Poulomi
- You have accessIf the KI Is Defined by the Free Energy of Binding to P-Glycoprotein, Which Kinetic Parameters Define the IC50 for the Madin-Darby Canine Kidney II Cell Line Overexpressing Human Multidrug Resistance 1 Confluent Cell Monolayer?Annie Albin Lumen, Poulomi Acharya, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2010, 38 (2) 260-269; DOI: https://doi.org/10.1124/dmd.109.029843
Adachi, Mayuko
- You have accessA Single Amino Acid Substitution Confers High Cinchonidine Oxidation Activity Comparable with That of Rabbit to Monkey Aldehyde Oxidase 1Kensuke Fukiya, Kunio Itoh, Satoshi Yamaguchi, Akiko Kishiba, Mayuko Adachi, Nobuaki Watanabe and Yorihisa TanakaDrug Metabolism and Disposition February 2010, 38 (2) 302-307; DOI: https://doi.org/10.1124/dmd.109.030064
Akabane, Takafumi
- You have accessA Comparison of Pharmacokinetics between Humans and MonkeysTakafumi Akabane, Kenji Tabata, Keitaro Kadono, Shuichi Sakuda, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition February 2010, 38 (2) 308-316; DOI: https://doi.org/10.1124/dmd.109.028829
Ansede, John H.
- You have accessAn In Vitro Assay to Assess Transporter-Based Cholestatic Hepatotoxicity Using Sandwich-Cultured Rat HepatocytesJohn H. Ansede, William R. Smith, Cassandra H. Perry, Robert L. St. Claire and Kenneth R. BrouwerDrug Metabolism and Disposition February 2010, 38 (2) 276-280; DOI: https://doi.org/10.1124/dmd.109.028407
Ayrton, Andrew
- You have accessIf the KI Is Defined by the Free Energy of Binding to P-Glycoprotein, Which Kinetic Parameters Define the IC50 for the Madin-Darby Canine Kidney II Cell Line Overexpressing Human Multidrug Resistance 1 Confluent Cell Monolayer?Annie Albin Lumen, Poulomi Acharya, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2010, 38 (2) 260-269; DOI: https://doi.org/10.1124/dmd.109.029843
B
Bai, Xue
- You have accessIsolation and Identification of Urinary Metabolites of Kakkalide in RatsXue Bai, Yuanyuan Xie, Jia Liu, Jialin Qu, Yoshihiro Kano and Dan YuanDrug Metabolism and Disposition February 2010, 38 (2) 281-286; DOI: https://doi.org/10.1124/dmd.109.028555
Barron, Denis
- You have accessIn Vivo Bioavailability, Absorption, Excretion, and Pharmacokinetics of [14C]Procyanidin B2 in Male RatsStavroula Stoupi, Gary Williamson, Florian Viton, Denis Barron, Laurence J. King, Jonathan E. Brown and Michael N. CliffordDrug Metabolism and Disposition February 2010, 38 (2) 287-291; DOI: https://doi.org/10.1124/dmd.109.030304
Bentz, Joe
- You have accessIf the KI Is Defined by the Free Energy of Binding to P-Glycoprotein, Which Kinetic Parameters Define the IC50 for the Madin-Darby Canine Kidney II Cell Line Overexpressing Human Multidrug Resistance 1 Confluent Cell Monolayer?Annie Albin Lumen, Poulomi Acharya, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2010, 38 (2) 260-269; DOI: https://doi.org/10.1124/dmd.109.029843
Berry, Loren
- You have accessRelationship between Passive Permeability, Efflux, and Predictability of Clearance from In Vitro Metabolic Intrinsic ClearanceLiyue Huang, Loren Berry, Sindhura Ganga, Brett Janosky, April Chen, Jonathan Roberts, Adria E. Colletti and Min-Hwa Jasmine LinDrug Metabolism and Disposition February 2010, 38 (2) 223-231; DOI: https://doi.org/10.1124/dmd.109.029066
Betton, Graham R.
- You have accessExpression and Localization of Rat Aldo-Keto Reductases and Induction of the 1B13 and 1D2 Isoforms by Phenolic AntioxidantsA. Kenneth MacLeod, Vincent P. Kelly, Larry G. Higgins, Michael O. Kelleher, Sally A. Price, Alison L. Bigley, Graham R. Betton and John D. HayesDrug Metabolism and Disposition February 2010, 38 (2) 341-346; DOI: https://doi.org/10.1124/dmd.109.030544
Bigley, Alison L.
- You have accessExpression and Localization of Rat Aldo-Keto Reductases and Induction of the 1B13 and 1D2 Isoforms by Phenolic AntioxidantsA. Kenneth MacLeod, Vincent P. Kelly, Larry G. Higgins, Michael O. Kelleher, Sally A. Price, Alison L. Bigley, Graham R. Betton and John D. HayesDrug Metabolism and Disposition February 2010, 38 (2) 341-346; DOI: https://doi.org/10.1124/dmd.109.030544
Brouwer, Kenneth R.
- You have accessAn In Vitro Assay to Assess Transporter-Based Cholestatic Hepatotoxicity Using Sandwich-Cultured Rat HepatocytesJohn H. Ansede, William R. Smith, Cassandra H. Perry, Robert L. St. Claire and Kenneth R. BrouwerDrug Metabolism and Disposition February 2010, 38 (2) 276-280; DOI: https://doi.org/10.1124/dmd.109.028407
Brown, Jonathan E.
- You have accessIn Vivo Bioavailability, Absorption, Excretion, and Pharmacokinetics of [14C]Procyanidin B2 in Male RatsStavroula Stoupi, Gary Williamson, Florian Viton, Denis Barron, Laurence J. King, Jonathan E. Brown and Michael N. CliffordDrug Metabolism and Disposition February 2010, 38 (2) 287-291; DOI: https://doi.org/10.1124/dmd.109.030304
C
Casey Laizure, S.
- You have accessThe Effect of Ethanol on Oral Cocaine Pharmacokinetics Reveals an Unrecognized Class of Ethanol-Mediated Drug InteractionsRobert B. Parker and S. Casey LaizureDrug Metabolism and Disposition February 2010, 38 (2) 317-322; DOI: https://doi.org/10.1124/dmd.109.030056
Chen, April
- You have accessRelationship between Passive Permeability, Efflux, and Predictability of Clearance from In Vitro Metabolic Intrinsic ClearanceLiyue Huang, Loren Berry, Sindhura Ganga, Brett Janosky, April Chen, Jonathan Roberts, Adria E. Colletti and Min-Hwa Jasmine LinDrug Metabolism and Disposition February 2010, 38 (2) 223-231; DOI: https://doi.org/10.1124/dmd.109.029066
Chiap, Patrice
- You have accessCoupling of Liquid Chromatography/Tandem Mass Spectrometry and Liquid Chromatography/Solid-Phase Extraction/NMR Techniques for the Structural Identification of Metabolites following In Vitro Biotransformation of SUR1-Selective ATP-Sensitive Potassium Channel OpenersFlorian Gillotin, Patrice Chiap, Michel Frédérich, Jean-Claude Van Heugen, Pierre Francotte, Philippe Lebrun, Bernard Pirotte and Pascal de TullioDrug Metabolism and Disposition February 2010, 38 (2) 232-240; DOI: https://doi.org/10.1124/dmd.109.028928
Clifford, Michael N.
- You have accessIn Vivo Bioavailability, Absorption, Excretion, and Pharmacokinetics of [14C]Procyanidin B2 in Male RatsStavroula Stoupi, Gary Williamson, Florian Viton, Denis Barron, Laurence J. King, Jonathan E. Brown and Michael N. CliffordDrug Metabolism and Disposition February 2010, 38 (2) 287-291; DOI: https://doi.org/10.1124/dmd.109.030304
Clouser-Roche, Andrea
- You have accessIdentification of Novel Substrates for Human Cytochrome P450 2J2Caroline A. Lee, David Neul, Andrea Clouser-Roche, Deepak Dalvie, Michael R. Wester, Ying Jiang, J. P. Jones, Sascha Freiwald, Michael Zientek and Rheem A. TotahDrug Metabolism and Disposition February 2010, 38 (2) 347-356; DOI: https://doi.org/10.1124/dmd.109.030270
Colletti, Adria E.
- You have accessRelationship between Passive Permeability, Efflux, and Predictability of Clearance from In Vitro Metabolic Intrinsic ClearanceLiyue Huang, Loren Berry, Sindhura Ganga, Brett Janosky, April Chen, Jonathan Roberts, Adria E. Colletti and Min-Hwa Jasmine LinDrug Metabolism and Disposition February 2010, 38 (2) 223-231; DOI: https://doi.org/10.1124/dmd.109.029066
D
Dalvie, Deepak
- You have accessIdentification of Novel Substrates for Human Cytochrome P450 2J2Caroline A. Lee, David Neul, Andrea Clouser-Roche, Deepak Dalvie, Michael R. Wester, Ying Jiang, J. P. Jones, Sascha Freiwald, Michael Zientek and Rheem A. TotahDrug Metabolism and Disposition February 2010, 38 (2) 347-356; DOI: https://doi.org/10.1124/dmd.109.030270
de Tullio, Pascal
- You have accessCoupling of Liquid Chromatography/Tandem Mass Spectrometry and Liquid Chromatography/Solid-Phase Extraction/NMR Techniques for the Structural Identification of Metabolites following In Vitro Biotransformation of SUR1-Selective ATP-Sensitive Potassium Channel OpenersFlorian Gillotin, Patrice Chiap, Michel Frédérich, Jean-Claude Van Heugen, Pierre Francotte, Philippe Lebrun, Bernard Pirotte and Pascal de TullioDrug Metabolism and Disposition February 2010, 38 (2) 232-240; DOI: https://doi.org/10.1124/dmd.109.028928
E
Ellens, Harma
- You have accessIf the KI Is Defined by the Free Energy of Binding to P-Glycoprotein, Which Kinetic Parameters Define the IC50 for the Madin-Darby Canine Kidney II Cell Line Overexpressing Human Multidrug Resistance 1 Confluent Cell Monolayer?Annie Albin Lumen, Poulomi Acharya, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2010, 38 (2) 260-269; DOI: https://doi.org/10.1124/dmd.109.029843
F
Francotte, Pierre
- You have accessCoupling of Liquid Chromatography/Tandem Mass Spectrometry and Liquid Chromatography/Solid-Phase Extraction/NMR Techniques for the Structural Identification of Metabolites following In Vitro Biotransformation of SUR1-Selective ATP-Sensitive Potassium Channel OpenersFlorian Gillotin, Patrice Chiap, Michel Frédérich, Jean-Claude Van Heugen, Pierre Francotte, Philippe Lebrun, Bernard Pirotte and Pascal de TullioDrug Metabolism and Disposition February 2010, 38 (2) 232-240; DOI: https://doi.org/10.1124/dmd.109.028928
Frédérich, Michel
- You have accessCoupling of Liquid Chromatography/Tandem Mass Spectrometry and Liquid Chromatography/Solid-Phase Extraction/NMR Techniques for the Structural Identification of Metabolites following In Vitro Biotransformation of SUR1-Selective ATP-Sensitive Potassium Channel OpenersFlorian Gillotin, Patrice Chiap, Michel Frédérich, Jean-Claude Van Heugen, Pierre Francotte, Philippe Lebrun, Bernard Pirotte and Pascal de TullioDrug Metabolism and Disposition February 2010, 38 (2) 232-240; DOI: https://doi.org/10.1124/dmd.109.028928
Freiwald, Sascha
- You have accessIdentification of Novel Substrates for Human Cytochrome P450 2J2Caroline A. Lee, David Neul, Andrea Clouser-Roche, Deepak Dalvie, Michael R. Wester, Ying Jiang, J. P. Jones, Sascha Freiwald, Michael Zientek and Rheem A. TotahDrug Metabolism and Disposition February 2010, 38 (2) 347-356; DOI: https://doi.org/10.1124/dmd.109.030270
Frye, Reginald F.
- You have accessInhibition of Intestinal and Hepatic Glucuronidation of Mycophenolic Acid by Ginkgo biloba Extract and FlavonoidsMohamed-Eslam F. Mohamed and Reginald F. FryeDrug Metabolism and Disposition February 2010, 38 (2) 270-275; DOI: https://doi.org/10.1124/dmd.109.030080
Fukiya, Kensuke
- You have accessA Single Amino Acid Substitution Confers High Cinchonidine Oxidation Activity Comparable with That of Rabbit to Monkey Aldehyde Oxidase 1Kensuke Fukiya, Kunio Itoh, Satoshi Yamaguchi, Akiko Kishiba, Mayuko Adachi, Nobuaki Watanabe and Yorihisa TanakaDrug Metabolism and Disposition February 2010, 38 (2) 302-307; DOI: https://doi.org/10.1124/dmd.109.030064
Fukuzaki, Koichiro
- You have accessGenetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus MacaquesYasuhiro Uno, Akinori Matsushita, Naoki Osada, Shotaro Uehara, Sakae Kohara, Ryoichi Nagata, Koichiro Fukuzaki, Masahiro Utoh, Norie Murayamay and Hiroshi YamazakiDrug Metabolism and Disposition February 2010, 38 (2) 209-214; DOI: https://doi.org/10.1124/dmd.109.029710
G
Ganga, Sindhura
- You have accessRelationship between Passive Permeability, Efflux, and Predictability of Clearance from In Vitro Metabolic Intrinsic ClearanceLiyue Huang, Loren Berry, Sindhura Ganga, Brett Janosky, April Chen, Jonathan Roberts, Adria E. Colletti and Min-Hwa Jasmine LinDrug Metabolism and Disposition February 2010, 38 (2) 223-231; DOI: https://doi.org/10.1124/dmd.109.029066
Gillotin, Florian
- You have accessCoupling of Liquid Chromatography/Tandem Mass Spectrometry and Liquid Chromatography/Solid-Phase Extraction/NMR Techniques for the Structural Identification of Metabolites following In Vitro Biotransformation of SUR1-Selective ATP-Sensitive Potassium Channel OpenersFlorian Gillotin, Patrice Chiap, Michel Frédérich, Jean-Claude Van Heugen, Pierre Francotte, Philippe Lebrun, Bernard Pirotte and Pascal de TullioDrug Metabolism and Disposition February 2010, 38 (2) 232-240; DOI: https://doi.org/10.1124/dmd.109.028928
Gorski, J. Christopher
- You have accessPhysiologically Based Pharmacokinetic Model of Mechanism-Based Inhibition of CYP3A by ClarithromycinSara K. Quinney, Xin Zhang, Aroonrut Lucksiri, J. Christopher Gorski, Lang Li and Stephen D. HallDrug Metabolism and Disposition February 2010, 38 (2) 241-248; DOI: https://doi.org/10.1124/dmd.109.028746
Gunduz, Mithat
- You have accessSpecies Differences in the Biotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist: The Effects of Distinct Glucuronide Metabolites on Overall Compound DispositionChristopher L. Shaffer, Mithat Gunduz, Tim F. Ryder and Thomas N. O'ConnellDrug Metabolism and Disposition February 2010, 38 (2) 292-301; DOI: https://doi.org/10.1124/dmd.109.030171
H
Hall, Stephen D.
- You have accessPhysiologically Based Pharmacokinetic Model of Mechanism-Based Inhibition of CYP3A by ClarithromycinSara K. Quinney, Xin Zhang, Aroonrut Lucksiri, J. Christopher Gorski, Lang Li and Stephen D. HallDrug Metabolism and Disposition February 2010, 38 (2) 241-248; DOI: https://doi.org/10.1124/dmd.109.028746
Hayes, John D.
- You have accessExpression and Localization of Rat Aldo-Keto Reductases and Induction of the 1B13 and 1D2 Isoforms by Phenolic AntioxidantsA. Kenneth MacLeod, Vincent P. Kelly, Larry G. Higgins, Michael O. Kelleher, Sally A. Price, Alison L. Bigley, Graham R. Betton and John D. HayesDrug Metabolism and Disposition February 2010, 38 (2) 341-346; DOI: https://doi.org/10.1124/dmd.109.030544
Higgins, Larry G.
- You have accessExpression and Localization of Rat Aldo-Keto Reductases and Induction of the 1B13 and 1D2 Isoforms by Phenolic AntioxidantsA. Kenneth MacLeod, Vincent P. Kelly, Larry G. Higgins, Michael O. Kelleher, Sally A. Price, Alison L. Bigley, Graham R. Betton and John D. HayesDrug Metabolism and Disposition February 2010, 38 (2) 341-346; DOI: https://doi.org/10.1124/dmd.109.030544
Hori, Katsuyuki
- You have accessTime-Dependent Inhibitory Effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04.9]octacos-18-ene-2,3,10,16-tetrone (FK1706), a Novel Nonimmunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in VitroTsuyoshi Minematsu, Jennifer Lee, Jiuhong Zha, Selina Moy, Donna Kowalski, Katsuyuki Hori, Koji Ishibashi, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition February 2010, 38 (2) 249-259; DOI: https://doi.org/10.1124/dmd.109.029280
Hu, Zhuohan
- You have accessInvestigation of the Rate-Determining Process in the Hepatic Elimination of HMG-CoA Reductase Inhibitors in Rats and HumansTakao Watanabe, Hiroyuki Kusuhara, Kazuya Maeda, Hiroshi Kanamaru, Yoshikazu Saito, Zhuohan Hu and Yuichi SugiyamaDrug Metabolism and Disposition February 2010, 38 (2) 215-222; DOI: https://doi.org/10.1124/dmd.109.030254
Huang, Liyue
- You have accessRelationship between Passive Permeability, Efflux, and Predictability of Clearance from In Vitro Metabolic Intrinsic ClearanceLiyue Huang, Loren Berry, Sindhura Ganga, Brett Janosky, April Chen, Jonathan Roberts, Adria E. Colletti and Min-Hwa Jasmine LinDrug Metabolism and Disposition February 2010, 38 (2) 223-231; DOI: https://doi.org/10.1124/dmd.109.029066
I
Imai, Teruko
- You have accessDevelopment of a Novel System for Estimating Human Intestinal Absorption Using Caco-2 Cells in the Absence of Esterase ActivityKayoko Ohura, Hisae Sakamoto, Shin-ichi Ninomiya and Teruko ImaiDrug Metabolism and Disposition February 2010, 38 (2) 323-331; DOI: https://doi.org/10.1124/dmd.109.029413
Ishibashi, Koji
- You have accessTime-Dependent Inhibitory Effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04.9]octacos-18-ene-2,3,10,16-tetrone (FK1706), a Novel Nonimmunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in VitroTsuyoshi Minematsu, Jennifer Lee, Jiuhong Zha, Selina Moy, Donna Kowalski, Katsuyuki Hori, Koji Ishibashi, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition February 2010, 38 (2) 249-259; DOI: https://doi.org/10.1124/dmd.109.029280
Itoh, Kunio
- You have accessA Single Amino Acid Substitution Confers High Cinchonidine Oxidation Activity Comparable with That of Rabbit to Monkey Aldehyde Oxidase 1Kensuke Fukiya, Kunio Itoh, Satoshi Yamaguchi, Akiko Kishiba, Mayuko Adachi, Nobuaki Watanabe and Yorihisa TanakaDrug Metabolism and Disposition February 2010, 38 (2) 302-307; DOI: https://doi.org/10.1124/dmd.109.030064
J
Janosky, Brett
- You have accessRelationship between Passive Permeability, Efflux, and Predictability of Clearance from In Vitro Metabolic Intrinsic ClearanceLiyue Huang, Loren Berry, Sindhura Ganga, Brett Janosky, April Chen, Jonathan Roberts, Adria E. Colletti and Min-Hwa Jasmine LinDrug Metabolism and Disposition February 2010, 38 (2) 223-231; DOI: https://doi.org/10.1124/dmd.109.029066
Jiang, Ying
- You have accessIdentification of Novel Substrates for Human Cytochrome P450 2J2Caroline A. Lee, David Neul, Andrea Clouser-Roche, Deepak Dalvie, Michael R. Wester, Ying Jiang, J. P. Jones, Sascha Freiwald, Michael Zientek and Rheem A. TotahDrug Metabolism and Disposition February 2010, 38 (2) 347-356; DOI: https://doi.org/10.1124/dmd.109.030270
Jones, J. P.
- You have accessIdentification of Novel Substrates for Human Cytochrome P450 2J2Caroline A. Lee, David Neul, Andrea Clouser-Roche, Deepak Dalvie, Michael R. Wester, Ying Jiang, J. P. Jones, Sascha Freiwald, Michael Zientek and Rheem A. TotahDrug Metabolism and Disposition February 2010, 38 (2) 347-356; DOI: https://doi.org/10.1124/dmd.109.030270
K
Kadono, Keitaro
- You have accessA Comparison of Pharmacokinetics between Humans and MonkeysTakafumi Akabane, Kenji Tabata, Keitaro Kadono, Shuichi Sakuda, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition February 2010, 38 (2) 308-316; DOI: https://doi.org/10.1124/dmd.109.028829
Kamimura, Hidetaka
- You have accessTime-Dependent Inhibitory Effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04.9]octacos-18-ene-2,3,10,16-tetrone (FK1706), a Novel Nonimmunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in VitroTsuyoshi Minematsu, Jennifer Lee, Jiuhong Zha, Selina Moy, Donna Kowalski, Katsuyuki Hori, Koji Ishibashi, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition February 2010, 38 (2) 249-259; DOI: https://doi.org/10.1124/dmd.109.029280
Kanamaru, Hiroshi
- You have accessInvestigation of the Rate-Determining Process in the Hepatic Elimination of HMG-CoA Reductase Inhibitors in Rats and HumansTakao Watanabe, Hiroyuki Kusuhara, Kazuya Maeda, Hiroshi Kanamaru, Yoshikazu Saito, Zhuohan Hu and Yuichi SugiyamaDrug Metabolism and Disposition February 2010, 38 (2) 215-222; DOI: https://doi.org/10.1124/dmd.109.030254
Kano, Yoshihiro
- You have accessIsolation and Identification of Urinary Metabolites of Kakkalide in RatsXue Bai, Yuanyuan Xie, Jia Liu, Jialin Qu, Yoshihiro Kano and Dan YuanDrug Metabolism and Disposition February 2010, 38 (2) 281-286; DOI: https://doi.org/10.1124/dmd.109.028555
Kelleher, Michael O.
- You have accessExpression and Localization of Rat Aldo-Keto Reductases and Induction of the 1B13 and 1D2 Isoforms by Phenolic AntioxidantsA. Kenneth MacLeod, Vincent P. Kelly, Larry G. Higgins, Michael O. Kelleher, Sally A. Price, Alison L. Bigley, Graham R. Betton and John D. HayesDrug Metabolism and Disposition February 2010, 38 (2) 341-346; DOI: https://doi.org/10.1124/dmd.109.030544
Kelly, Vincent P.
- You have accessExpression and Localization of Rat Aldo-Keto Reductases and Induction of the 1B13 and 1D2 Isoforms by Phenolic AntioxidantsA. Kenneth MacLeod, Vincent P. Kelly, Larry G. Higgins, Michael O. Kelleher, Sally A. Price, Alison L. Bigley, Graham R. Betton and John D. HayesDrug Metabolism and Disposition February 2010, 38 (2) 341-346; DOI: https://doi.org/10.1124/dmd.109.030544
King, Laurence J.
- You have accessIn Vivo Bioavailability, Absorption, Excretion, and Pharmacokinetics of [14C]Procyanidin B2 in Male RatsStavroula Stoupi, Gary Williamson, Florian Viton, Denis Barron, Laurence J. King, Jonathan E. Brown and Michael N. CliffordDrug Metabolism and Disposition February 2010, 38 (2) 287-291; DOI: https://doi.org/10.1124/dmd.109.030304
Kishiba, Akiko
- You have accessA Single Amino Acid Substitution Confers High Cinchonidine Oxidation Activity Comparable with That of Rabbit to Monkey Aldehyde Oxidase 1Kensuke Fukiya, Kunio Itoh, Satoshi Yamaguchi, Akiko Kishiba, Mayuko Adachi, Nobuaki Watanabe and Yorihisa TanakaDrug Metabolism and Disposition February 2010, 38 (2) 302-307; DOI: https://doi.org/10.1124/dmd.109.030064
Kohara, Sakae
- You have accessGenetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus MacaquesYasuhiro Uno, Akinori Matsushita, Naoki Osada, Shotaro Uehara, Sakae Kohara, Ryoichi Nagata, Koichiro Fukuzaki, Masahiro Utoh, Norie Murayamay and Hiroshi YamazakiDrug Metabolism and Disposition February 2010, 38 (2) 209-214; DOI: https://doi.org/10.1124/dmd.109.029710
Kowalski, Donna
- You have accessTime-Dependent Inhibitory Effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04.9]octacos-18-ene-2,3,10,16-tetrone (FK1706), a Novel Nonimmunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in VitroTsuyoshi Minematsu, Jennifer Lee, Jiuhong Zha, Selina Moy, Donna Kowalski, Katsuyuki Hori, Koji Ishibashi, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition February 2010, 38 (2) 249-259; DOI: https://doi.org/10.1124/dmd.109.029280
Kranendonk, Michel
- You have accessHuman Cytochrome P450 Oxidoreductase Deficiency Caused by the Y181D Mutation: Molecular Consequences and Rescue of DefectChristopher C. Marohnic, Satya P. Panda, Karen McCammon, José Rueff, Bettie Sue Siler Masters and Michel KranendonkDrug Metabolism and Disposition February 2010, 38 (2) 332-340; DOI: https://doi.org/10.1124/dmd.109.030445
Kusuhara, Hiroyuki
- You have accessInvestigation of the Rate-Determining Process in the Hepatic Elimination of HMG-CoA Reductase Inhibitors in Rats and HumansTakao Watanabe, Hiroyuki Kusuhara, Kazuya Maeda, Hiroshi Kanamaru, Yoshikazu Saito, Zhuohan Hu and Yuichi SugiyamaDrug Metabolism and Disposition February 2010, 38 (2) 215-222; DOI: https://doi.org/10.1124/dmd.109.030254
L
Lebrun, Philippe
- You have accessCoupling of Liquid Chromatography/Tandem Mass Spectrometry and Liquid Chromatography/Solid-Phase Extraction/NMR Techniques for the Structural Identification of Metabolites following In Vitro Biotransformation of SUR1-Selective ATP-Sensitive Potassium Channel OpenersFlorian Gillotin, Patrice Chiap, Michel Frédérich, Jean-Claude Van Heugen, Pierre Francotte, Philippe Lebrun, Bernard Pirotte and Pascal de TullioDrug Metabolism and Disposition February 2010, 38 (2) 232-240; DOI: https://doi.org/10.1124/dmd.109.028928
Lee, Caroline A.
- You have accessIdentification of Novel Substrates for Human Cytochrome P450 2J2Caroline A. Lee, David Neul, Andrea Clouser-Roche, Deepak Dalvie, Michael R. Wester, Ying Jiang, J. P. Jones, Sascha Freiwald, Michael Zientek and Rheem A. TotahDrug Metabolism and Disposition February 2010, 38 (2) 347-356; DOI: https://doi.org/10.1124/dmd.109.030270
Lee, Jennifer
- You have accessTime-Dependent Inhibitory Effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04.9]octacos-18-ene-2,3,10,16-tetrone (FK1706), a Novel Nonimmunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in VitroTsuyoshi Minematsu, Jennifer Lee, Jiuhong Zha, Selina Moy, Donna Kowalski, Katsuyuki Hori, Koji Ishibashi, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition February 2010, 38 (2) 249-259; DOI: https://doi.org/10.1124/dmd.109.029280
Li, Lang
- You have accessPhysiologically Based Pharmacokinetic Model of Mechanism-Based Inhibition of CYP3A by ClarithromycinSara K. Quinney, Xin Zhang, Aroonrut Lucksiri, J. Christopher Gorski, Lang Li and Stephen D. HallDrug Metabolism and Disposition February 2010, 38 (2) 241-248; DOI: https://doi.org/10.1124/dmd.109.028746
Lin, Min-Hwa Jasmine
- You have accessRelationship between Passive Permeability, Efflux, and Predictability of Clearance from In Vitro Metabolic Intrinsic ClearanceLiyue Huang, Loren Berry, Sindhura Ganga, Brett Janosky, April Chen, Jonathan Roberts, Adria E. Colletti and Min-Hwa Jasmine LinDrug Metabolism and Disposition February 2010, 38 (2) 223-231; DOI: https://doi.org/10.1124/dmd.109.029066
Liu, Jia
- You have accessIsolation and Identification of Urinary Metabolites of Kakkalide in RatsXue Bai, Yuanyuan Xie, Jia Liu, Jialin Qu, Yoshihiro Kano and Dan YuanDrug Metabolism and Disposition February 2010, 38 (2) 281-286; DOI: https://doi.org/10.1124/dmd.109.028555
Lucksiri, Aroonrut
- You have accessPhysiologically Based Pharmacokinetic Model of Mechanism-Based Inhibition of CYP3A by ClarithromycinSara K. Quinney, Xin Zhang, Aroonrut Lucksiri, J. Christopher Gorski, Lang Li and Stephen D. HallDrug Metabolism and Disposition February 2010, 38 (2) 241-248; DOI: https://doi.org/10.1124/dmd.109.028746
Lumen, Annie Albin
- You have accessIf the KI Is Defined by the Free Energy of Binding to P-Glycoprotein, Which Kinetic Parameters Define the IC50 for the Madin-Darby Canine Kidney II Cell Line Overexpressing Human Multidrug Resistance 1 Confluent Cell Monolayer?Annie Albin Lumen, Poulomi Acharya, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2010, 38 (2) 260-269; DOI: https://doi.org/10.1124/dmd.109.029843
M
MacLeod, A. Kenneth
- You have accessExpression and Localization of Rat Aldo-Keto Reductases and Induction of the 1B13 and 1D2 Isoforms by Phenolic AntioxidantsA. Kenneth MacLeod, Vincent P. Kelly, Larry G. Higgins, Michael O. Kelleher, Sally A. Price, Alison L. Bigley, Graham R. Betton and John D. HayesDrug Metabolism and Disposition February 2010, 38 (2) 341-346; DOI: https://doi.org/10.1124/dmd.109.030544
Maeda, Kazuya
- You have accessInvestigation of the Rate-Determining Process in the Hepatic Elimination of HMG-CoA Reductase Inhibitors in Rats and HumansTakao Watanabe, Hiroyuki Kusuhara, Kazuya Maeda, Hiroshi Kanamaru, Yoshikazu Saito, Zhuohan Hu and Yuichi SugiyamaDrug Metabolism and Disposition February 2010, 38 (2) 215-222; DOI: https://doi.org/10.1124/dmd.109.030254
Marohnic, Christopher C.
- You have accessHuman Cytochrome P450 Oxidoreductase Deficiency Caused by the Y181D Mutation: Molecular Consequences and Rescue of DefectChristopher C. Marohnic, Satya P. Panda, Karen McCammon, José Rueff, Bettie Sue Siler Masters and Michel KranendonkDrug Metabolism and Disposition February 2010, 38 (2) 332-340; DOI: https://doi.org/10.1124/dmd.109.030445
Masters, Bettie Sue Siler
- You have accessHuman Cytochrome P450 Oxidoreductase Deficiency Caused by the Y181D Mutation: Molecular Consequences and Rescue of DefectChristopher C. Marohnic, Satya P. Panda, Karen McCammon, José Rueff, Bettie Sue Siler Masters and Michel KranendonkDrug Metabolism and Disposition February 2010, 38 (2) 332-340; DOI: https://doi.org/10.1124/dmd.109.030445
Matsushita, Akinori
- You have accessGenetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus MacaquesYasuhiro Uno, Akinori Matsushita, Naoki Osada, Shotaro Uehara, Sakae Kohara, Ryoichi Nagata, Koichiro Fukuzaki, Masahiro Utoh, Norie Murayamay and Hiroshi YamazakiDrug Metabolism and Disposition February 2010, 38 (2) 209-214; DOI: https://doi.org/10.1124/dmd.109.029710
McCammon, Karen
- You have accessHuman Cytochrome P450 Oxidoreductase Deficiency Caused by the Y181D Mutation: Molecular Consequences and Rescue of DefectChristopher C. Marohnic, Satya P. Panda, Karen McCammon, José Rueff, Bettie Sue Siler Masters and Michel KranendonkDrug Metabolism and Disposition February 2010, 38 (2) 332-340; DOI: https://doi.org/10.1124/dmd.109.030445
Minematsu, Tsuyoshi
- You have accessTime-Dependent Inhibitory Effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04.9]octacos-18-ene-2,3,10,16-tetrone (FK1706), a Novel Nonimmunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in VitroTsuyoshi Minematsu, Jennifer Lee, Jiuhong Zha, Selina Moy, Donna Kowalski, Katsuyuki Hori, Koji Ishibashi, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition February 2010, 38 (2) 249-259; DOI: https://doi.org/10.1124/dmd.109.029280
Mohamed, Mohamed-Eslam F.
- You have accessInhibition of Intestinal and Hepatic Glucuronidation of Mycophenolic Acid by Ginkgo biloba Extract and FlavonoidsMohamed-Eslam F. Mohamed and Reginald F. FryeDrug Metabolism and Disposition February 2010, 38 (2) 270-275; DOI: https://doi.org/10.1124/dmd.109.030080
Moy, Selina
- You have accessTime-Dependent Inhibitory Effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04.9]octacos-18-ene-2,3,10,16-tetrone (FK1706), a Novel Nonimmunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in VitroTsuyoshi Minematsu, Jennifer Lee, Jiuhong Zha, Selina Moy, Donna Kowalski, Katsuyuki Hori, Koji Ishibashi, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition February 2010, 38 (2) 249-259; DOI: https://doi.org/10.1124/dmd.109.029280
Murayamay, Norie
- You have accessGenetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus MacaquesYasuhiro Uno, Akinori Matsushita, Naoki Osada, Shotaro Uehara, Sakae Kohara, Ryoichi Nagata, Koichiro Fukuzaki, Masahiro Utoh, Norie Murayamay and Hiroshi YamazakiDrug Metabolism and Disposition February 2010, 38 (2) 209-214; DOI: https://doi.org/10.1124/dmd.109.029710
N
Nagata, Ryoichi
- You have accessGenetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus MacaquesYasuhiro Uno, Akinori Matsushita, Naoki Osada, Shotaro Uehara, Sakae Kohara, Ryoichi Nagata, Koichiro Fukuzaki, Masahiro Utoh, Norie Murayamay and Hiroshi YamazakiDrug Metabolism and Disposition February 2010, 38 (2) 209-214; DOI: https://doi.org/10.1124/dmd.109.029710
Neul, David
- You have accessIdentification of Novel Substrates for Human Cytochrome P450 2J2Caroline A. Lee, David Neul, Andrea Clouser-Roche, Deepak Dalvie, Michael R. Wester, Ying Jiang, J. P. Jones, Sascha Freiwald, Michael Zientek and Rheem A. TotahDrug Metabolism and Disposition February 2010, 38 (2) 347-356; DOI: https://doi.org/10.1124/dmd.109.030270
Ninomiya, Shin-ichi
- You have accessDevelopment of a Novel System for Estimating Human Intestinal Absorption Using Caco-2 Cells in the Absence of Esterase ActivityKayoko Ohura, Hisae Sakamoto, Shin-ichi Ninomiya and Teruko ImaiDrug Metabolism and Disposition February 2010, 38 (2) 323-331; DOI: https://doi.org/10.1124/dmd.109.029413
O
O'Connell, Thomas N.
- You have accessSpecies Differences in the Biotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist: The Effects of Distinct Glucuronide Metabolites on Overall Compound DispositionChristopher L. Shaffer, Mithat Gunduz, Tim F. Ryder and Thomas N. O'ConnellDrug Metabolism and Disposition February 2010, 38 (2) 292-301; DOI: https://doi.org/10.1124/dmd.109.030171
Ohura, Kayoko
- You have accessDevelopment of a Novel System for Estimating Human Intestinal Absorption Using Caco-2 Cells in the Absence of Esterase ActivityKayoko Ohura, Hisae Sakamoto, Shin-ichi Ninomiya and Teruko ImaiDrug Metabolism and Disposition February 2010, 38 (2) 323-331; DOI: https://doi.org/10.1124/dmd.109.029413
Osada, Naoki
- You have accessGenetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus MacaquesYasuhiro Uno, Akinori Matsushita, Naoki Osada, Shotaro Uehara, Sakae Kohara, Ryoichi Nagata, Koichiro Fukuzaki, Masahiro Utoh, Norie Murayamay and Hiroshi YamazakiDrug Metabolism and Disposition February 2010, 38 (2) 209-214; DOI: https://doi.org/10.1124/dmd.109.029710
P
Panda, Satya P.
- You have accessHuman Cytochrome P450 Oxidoreductase Deficiency Caused by the Y181D Mutation: Molecular Consequences and Rescue of DefectChristopher C. Marohnic, Satya P. Panda, Karen McCammon, José Rueff, Bettie Sue Siler Masters and Michel KranendonkDrug Metabolism and Disposition February 2010, 38 (2) 332-340; DOI: https://doi.org/10.1124/dmd.109.030445
Parker, Robert B.
- You have accessThe Effect of Ethanol on Oral Cocaine Pharmacokinetics Reveals an Unrecognized Class of Ethanol-Mediated Drug InteractionsRobert B. Parker and S. Casey LaizureDrug Metabolism and Disposition February 2010, 38 (2) 317-322; DOI: https://doi.org/10.1124/dmd.109.030056
Perry, Cassandra H.
- You have accessAn In Vitro Assay to Assess Transporter-Based Cholestatic Hepatotoxicity Using Sandwich-Cultured Rat HepatocytesJohn H. Ansede, William R. Smith, Cassandra H. Perry, Robert L. St. Claire and Kenneth R. BrouwerDrug Metabolism and Disposition February 2010, 38 (2) 276-280; DOI: https://doi.org/10.1124/dmd.109.028407
Pirotte, Bernard
- You have accessCoupling of Liquid Chromatography/Tandem Mass Spectrometry and Liquid Chromatography/Solid-Phase Extraction/NMR Techniques for the Structural Identification of Metabolites following In Vitro Biotransformation of SUR1-Selective ATP-Sensitive Potassium Channel OpenersFlorian Gillotin, Patrice Chiap, Michel Frédérich, Jean-Claude Van Heugen, Pierre Francotte, Philippe Lebrun, Bernard Pirotte and Pascal de TullioDrug Metabolism and Disposition February 2010, 38 (2) 232-240; DOI: https://doi.org/10.1124/dmd.109.028928
Polli, Joseph W.
- You have accessIf the KI Is Defined by the Free Energy of Binding to P-Glycoprotein, Which Kinetic Parameters Define the IC50 for the Madin-Darby Canine Kidney II Cell Line Overexpressing Human Multidrug Resistance 1 Confluent Cell Monolayer?Annie Albin Lumen, Poulomi Acharya, Joseph W. Polli, Andrew Ayrton, Harma Ellens and Joe BentzDrug Metabolism and Disposition February 2010, 38 (2) 260-269; DOI: https://doi.org/10.1124/dmd.109.029843
Price, Sally A.
- You have accessExpression and Localization of Rat Aldo-Keto Reductases and Induction of the 1B13 and 1D2 Isoforms by Phenolic AntioxidantsA. Kenneth MacLeod, Vincent P. Kelly, Larry G. Higgins, Michael O. Kelleher, Sally A. Price, Alison L. Bigley, Graham R. Betton and John D. HayesDrug Metabolism and Disposition February 2010, 38 (2) 341-346; DOI: https://doi.org/10.1124/dmd.109.030544
Q
Qu, Jialin
- You have accessIsolation and Identification of Urinary Metabolites of Kakkalide in RatsXue Bai, Yuanyuan Xie, Jia Liu, Jialin Qu, Yoshihiro Kano and Dan YuanDrug Metabolism and Disposition February 2010, 38 (2) 281-286; DOI: https://doi.org/10.1124/dmd.109.028555
Quinney, Sara K.
- You have accessPhysiologically Based Pharmacokinetic Model of Mechanism-Based Inhibition of CYP3A by ClarithromycinSara K. Quinney, Xin Zhang, Aroonrut Lucksiri, J. Christopher Gorski, Lang Li and Stephen D. HallDrug Metabolism and Disposition February 2010, 38 (2) 241-248; DOI: https://doi.org/10.1124/dmd.109.028746
R
Roberts, Jonathan
- You have accessRelationship between Passive Permeability, Efflux, and Predictability of Clearance from In Vitro Metabolic Intrinsic ClearanceLiyue Huang, Loren Berry, Sindhura Ganga, Brett Janosky, April Chen, Jonathan Roberts, Adria E. Colletti and Min-Hwa Jasmine LinDrug Metabolism and Disposition February 2010, 38 (2) 223-231; DOI: https://doi.org/10.1124/dmd.109.029066
Rueff, José
- You have accessHuman Cytochrome P450 Oxidoreductase Deficiency Caused by the Y181D Mutation: Molecular Consequences and Rescue of DefectChristopher C. Marohnic, Satya P. Panda, Karen McCammon, José Rueff, Bettie Sue Siler Masters and Michel KranendonkDrug Metabolism and Disposition February 2010, 38 (2) 332-340; DOI: https://doi.org/10.1124/dmd.109.030445
Ryder, Tim F.
- You have accessSpecies Differences in the Biotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist: The Effects of Distinct Glucuronide Metabolites on Overall Compound DispositionChristopher L. Shaffer, Mithat Gunduz, Tim F. Ryder and Thomas N. O'ConnellDrug Metabolism and Disposition February 2010, 38 (2) 292-301; DOI: https://doi.org/10.1124/dmd.109.030171
S
Saito, Yoshikazu
- You have accessInvestigation of the Rate-Determining Process in the Hepatic Elimination of HMG-CoA Reductase Inhibitors in Rats and HumansTakao Watanabe, Hiroyuki Kusuhara, Kazuya Maeda, Hiroshi Kanamaru, Yoshikazu Saito, Zhuohan Hu and Yuichi SugiyamaDrug Metabolism and Disposition February 2010, 38 (2) 215-222; DOI: https://doi.org/10.1124/dmd.109.030254
Sakamoto, Hisae
- You have accessDevelopment of a Novel System for Estimating Human Intestinal Absorption Using Caco-2 Cells in the Absence of Esterase ActivityKayoko Ohura, Hisae Sakamoto, Shin-ichi Ninomiya and Teruko ImaiDrug Metabolism and Disposition February 2010, 38 (2) 323-331; DOI: https://doi.org/10.1124/dmd.109.029413
Sakuda, Shuichi
- You have accessA Comparison of Pharmacokinetics between Humans and MonkeysTakafumi Akabane, Kenji Tabata, Keitaro Kadono, Shuichi Sakuda, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition February 2010, 38 (2) 308-316; DOI: https://doi.org/10.1124/dmd.109.028829
Shaffer, Christopher L.
- You have accessSpecies Differences in the Biotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist: The Effects of Distinct Glucuronide Metabolites on Overall Compound DispositionChristopher L. Shaffer, Mithat Gunduz, Tim F. Ryder and Thomas N. O'ConnellDrug Metabolism and Disposition February 2010, 38 (2) 292-301; DOI: https://doi.org/10.1124/dmd.109.030171
Smith, William R.
- You have accessAn In Vitro Assay to Assess Transporter-Based Cholestatic Hepatotoxicity Using Sandwich-Cultured Rat HepatocytesJohn H. Ansede, William R. Smith, Cassandra H. Perry, Robert L. St. Claire and Kenneth R. BrouwerDrug Metabolism and Disposition February 2010, 38 (2) 276-280; DOI: https://doi.org/10.1124/dmd.109.028407
St. Claire, Robert L.
- You have accessAn In Vitro Assay to Assess Transporter-Based Cholestatic Hepatotoxicity Using Sandwich-Cultured Rat HepatocytesJohn H. Ansede, William R. Smith, Cassandra H. Perry, Robert L. St. Claire and Kenneth R. BrouwerDrug Metabolism and Disposition February 2010, 38 (2) 276-280; DOI: https://doi.org/10.1124/dmd.109.028407
Stoupi, Stavroula
- You have accessIn Vivo Bioavailability, Absorption, Excretion, and Pharmacokinetics of [14C]Procyanidin B2 in Male RatsStavroula Stoupi, Gary Williamson, Florian Viton, Denis Barron, Laurence J. King, Jonathan E. Brown and Michael N. CliffordDrug Metabolism and Disposition February 2010, 38 (2) 287-291; DOI: https://doi.org/10.1124/dmd.109.030304
Sugiyama, Yuichi
- You have accessInvestigation of the Rate-Determining Process in the Hepatic Elimination of HMG-CoA Reductase Inhibitors in Rats and HumansTakao Watanabe, Hiroyuki Kusuhara, Kazuya Maeda, Hiroshi Kanamaru, Yoshikazu Saito, Zhuohan Hu and Yuichi SugiyamaDrug Metabolism and Disposition February 2010, 38 (2) 215-222; DOI: https://doi.org/10.1124/dmd.109.030254
T
Tabata, Kenji
- You have accessA Comparison of Pharmacokinetics between Humans and MonkeysTakafumi Akabane, Kenji Tabata, Keitaro Kadono, Shuichi Sakuda, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition February 2010, 38 (2) 308-316; DOI: https://doi.org/10.1124/dmd.109.028829
Tanaka, Yorihisa
- You have accessA Single Amino Acid Substitution Confers High Cinchonidine Oxidation Activity Comparable with That of Rabbit to Monkey Aldehyde Oxidase 1Kensuke Fukiya, Kunio Itoh, Satoshi Yamaguchi, Akiko Kishiba, Mayuko Adachi, Nobuaki Watanabe and Yorihisa TanakaDrug Metabolism and Disposition February 2010, 38 (2) 302-307; DOI: https://doi.org/10.1124/dmd.109.030064
Teramura, Toshio
- You have accessA Comparison of Pharmacokinetics between Humans and MonkeysTakafumi Akabane, Kenji Tabata, Keitaro Kadono, Shuichi Sakuda, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition February 2010, 38 (2) 308-316; DOI: https://doi.org/10.1124/dmd.109.028829
Terashita, Shigeyuki
- You have accessA Comparison of Pharmacokinetics between Humans and MonkeysTakafumi Akabane, Kenji Tabata, Keitaro Kadono, Shuichi Sakuda, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition February 2010, 38 (2) 308-316; DOI: https://doi.org/10.1124/dmd.109.028829
Totah, Rheem A.
- You have accessIdentification of Novel Substrates for Human Cytochrome P450 2J2Caroline A. Lee, David Neul, Andrea Clouser-Roche, Deepak Dalvie, Michael R. Wester, Ying Jiang, J. P. Jones, Sascha Freiwald, Michael Zientek and Rheem A. TotahDrug Metabolism and Disposition February 2010, 38 (2) 347-356; DOI: https://doi.org/10.1124/dmd.109.030270
U
Uehara, Shotaro
- You have accessGenetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus MacaquesYasuhiro Uno, Akinori Matsushita, Naoki Osada, Shotaro Uehara, Sakae Kohara, Ryoichi Nagata, Koichiro Fukuzaki, Masahiro Utoh, Norie Murayamay and Hiroshi YamazakiDrug Metabolism and Disposition February 2010, 38 (2) 209-214; DOI: https://doi.org/10.1124/dmd.109.029710
Uno, Yasuhiro
- You have accessGenetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus MacaquesYasuhiro Uno, Akinori Matsushita, Naoki Osada, Shotaro Uehara, Sakae Kohara, Ryoichi Nagata, Koichiro Fukuzaki, Masahiro Utoh, Norie Murayamay and Hiroshi YamazakiDrug Metabolism and Disposition February 2010, 38 (2) 209-214; DOI: https://doi.org/10.1124/dmd.109.029710
Usui, Takashi
- You have accessTime-Dependent Inhibitory Effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04.9]octacos-18-ene-2,3,10,16-tetrone (FK1706), a Novel Nonimmunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in VitroTsuyoshi Minematsu, Jennifer Lee, Jiuhong Zha, Selina Moy, Donna Kowalski, Katsuyuki Hori, Koji Ishibashi, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition February 2010, 38 (2) 249-259; DOI: https://doi.org/10.1124/dmd.109.029280
Utoh, Masahiro
- You have accessGenetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus MacaquesYasuhiro Uno, Akinori Matsushita, Naoki Osada, Shotaro Uehara, Sakae Kohara, Ryoichi Nagata, Koichiro Fukuzaki, Masahiro Utoh, Norie Murayamay and Hiroshi YamazakiDrug Metabolism and Disposition February 2010, 38 (2) 209-214; DOI: https://doi.org/10.1124/dmd.109.029710
V
Van Heugen, Jean-Claude
- You have accessCoupling of Liquid Chromatography/Tandem Mass Spectrometry and Liquid Chromatography/Solid-Phase Extraction/NMR Techniques for the Structural Identification of Metabolites following In Vitro Biotransformation of SUR1-Selective ATP-Sensitive Potassium Channel OpenersFlorian Gillotin, Patrice Chiap, Michel Frédérich, Jean-Claude Van Heugen, Pierre Francotte, Philippe Lebrun, Bernard Pirotte and Pascal de TullioDrug Metabolism and Disposition February 2010, 38 (2) 232-240; DOI: https://doi.org/10.1124/dmd.109.028928
Viton, Florian
- You have accessIn Vivo Bioavailability, Absorption, Excretion, and Pharmacokinetics of [14C]Procyanidin B2 in Male RatsStavroula Stoupi, Gary Williamson, Florian Viton, Denis Barron, Laurence J. King, Jonathan E. Brown and Michael N. CliffordDrug Metabolism and Disposition February 2010, 38 (2) 287-291; DOI: https://doi.org/10.1124/dmd.109.030304
W
Watanabe, Nobuaki
- You have accessA Single Amino Acid Substitution Confers High Cinchonidine Oxidation Activity Comparable with That of Rabbit to Monkey Aldehyde Oxidase 1Kensuke Fukiya, Kunio Itoh, Satoshi Yamaguchi, Akiko Kishiba, Mayuko Adachi, Nobuaki Watanabe and Yorihisa TanakaDrug Metabolism and Disposition February 2010, 38 (2) 302-307; DOI: https://doi.org/10.1124/dmd.109.030064
Watanabe, Takao
- You have accessInvestigation of the Rate-Determining Process in the Hepatic Elimination of HMG-CoA Reductase Inhibitors in Rats and HumansTakao Watanabe, Hiroyuki Kusuhara, Kazuya Maeda, Hiroshi Kanamaru, Yoshikazu Saito, Zhuohan Hu and Yuichi SugiyamaDrug Metabolism and Disposition February 2010, 38 (2) 215-222; DOI: https://doi.org/10.1124/dmd.109.030254
Wester, Michael R.
- You have accessIdentification of Novel Substrates for Human Cytochrome P450 2J2Caroline A. Lee, David Neul, Andrea Clouser-Roche, Deepak Dalvie, Michael R. Wester, Ying Jiang, J. P. Jones, Sascha Freiwald, Michael Zientek and Rheem A. TotahDrug Metabolism and Disposition February 2010, 38 (2) 347-356; DOI: https://doi.org/10.1124/dmd.109.030270
Williamson, Gary
- You have accessIn Vivo Bioavailability, Absorption, Excretion, and Pharmacokinetics of [14C]Procyanidin B2 in Male RatsStavroula Stoupi, Gary Williamson, Florian Viton, Denis Barron, Laurence J. King, Jonathan E. Brown and Michael N. CliffordDrug Metabolism and Disposition February 2010, 38 (2) 287-291; DOI: https://doi.org/10.1124/dmd.109.030304
X
Xie, Yuanyuan
- You have accessIsolation and Identification of Urinary Metabolites of Kakkalide in RatsXue Bai, Yuanyuan Xie, Jia Liu, Jialin Qu, Yoshihiro Kano and Dan YuanDrug Metabolism and Disposition February 2010, 38 (2) 281-286; DOI: https://doi.org/10.1124/dmd.109.028555
Y
Yamaguchi, Satoshi
- You have accessA Single Amino Acid Substitution Confers High Cinchonidine Oxidation Activity Comparable with That of Rabbit to Monkey Aldehyde Oxidase 1Kensuke Fukiya, Kunio Itoh, Satoshi Yamaguchi, Akiko Kishiba, Mayuko Adachi, Nobuaki Watanabe and Yorihisa TanakaDrug Metabolism and Disposition February 2010, 38 (2) 302-307; DOI: https://doi.org/10.1124/dmd.109.030064
Yamazaki, Hiroshi
- You have accessGenetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus MacaquesYasuhiro Uno, Akinori Matsushita, Naoki Osada, Shotaro Uehara, Sakae Kohara, Ryoichi Nagata, Koichiro Fukuzaki, Masahiro Utoh, Norie Murayamay and Hiroshi YamazakiDrug Metabolism and Disposition February 2010, 38 (2) 209-214; DOI: https://doi.org/10.1124/dmd.109.029710
Yuan, Dan
- You have accessIsolation and Identification of Urinary Metabolites of Kakkalide in RatsXue Bai, Yuanyuan Xie, Jia Liu, Jialin Qu, Yoshihiro Kano and Dan YuanDrug Metabolism and Disposition February 2010, 38 (2) 281-286; DOI: https://doi.org/10.1124/dmd.109.028555
Z
Zha, Jiuhong
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Zhang, Xin
- You have accessPhysiologically Based Pharmacokinetic Model of Mechanism-Based Inhibition of CYP3A by ClarithromycinSara K. Quinney, Xin Zhang, Aroonrut Lucksiri, J. Christopher Gorski, Lang Li and Stephen D. HallDrug Metabolism and Disposition February 2010, 38 (2) 241-248; DOI: https://doi.org/10.1124/dmd.109.028746
Zientek, Michael
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