Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn

Table of Contents

March 01, 2010; Volume 38,Issue 3

Short Communication

  • You have access
    Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
    Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
    Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991

Articles

  • You have access
    Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
    Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
    Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
  • You have access
    Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
    Mei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. Williams
    Drug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900
  • You have access
    Identification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based Simulator
    Jakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian Linnet
    Drug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551
  • You have access
    Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
    Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
    Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
  • You have access
    Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
    Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
    Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
  • You have access
    In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
    M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
    Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  • You have access
    New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
    Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
    Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
  • You have access
    In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
    Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
    Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
  • You have access
    Glucuronidation of Dihydrotestosterone and trans-Androsterone by Recombinant UDP-Glucuronosyltransferase (UGT) 1A4: Evidence for Multiple UGT1A4 Aglycone Binding Sites
    Jin Zhou, Timothy S. Tracy and Rory P. Remmel
    Drug Metabolism and Disposition March 2010, 38 (3) 431-440; DOI: https://doi.org/10.1124/dmd.109.028712
  • You have access
    Monocarboxylate Transporter-Mediated Transport of γ-Hydroxybutyric Acid in Human Intestinal Caco-2 Cells
    Wing Ki Lam, Melanie A. Felmlee and Marilyn E. Morris
    Drug Metabolism and Disposition March 2010, 38 (3) 441-447; DOI: https://doi.org/10.1124/dmd.109.030775
  • You have access
    In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
    Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
    Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  • You have access
    Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
    Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
    Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
  • You have access
    Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
    Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
    Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  • You have access
    UDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer Susceptibility
    Rene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip Lazarus
    Drug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569
  • You have access
    Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
    Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
    Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
  • You have access
    Metabolism and Excretion of the Novel Bioreductive Prodrug PR-104 in Mice, Rats, Dogs, and Humans
    Yongchuan Gu, Graham J. Atwell and William R. Wilson
    Drug Metabolism and Disposition March 2010, 38 (3) 498-508; DOI: https://doi.org/10.1124/dmd.109.030973
  • You have access
    Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombe
    Călin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias Bureik
    Drug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965
  • You have access
    Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
    Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
    Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
  • You have access
    Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
    Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
    Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668

Letters to the Editor

  • You have access
    Comment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
    Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng Chen
    Drug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825
  • You have access
    Response to Letter to the Editor on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
    Huadong Sun and K. Sandy Pang
    Drug Metabolism and Disposition March 2010, 38 (3) 536-537; DOI: https://doi.org/10.1124/dmd.109.031195
Back to top
PreviousNext

In this issue

Drug Metabolism and Disposition: 38 (3)
Drug Metabolism and Disposition
Vol. 38, Issue 3
1 Mar 2010
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
Sign up for alerts

Jump to

  • Short Communication
  • Articles
  • Letters to the Editor
  • Most Cited
  • Most Read
Loading
  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics