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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
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Index by author

March 01, 2010; Volume 38,Issue 3
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Andersson, Tommy B.

    1. You have access
      Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
  2. Anthérieu, Sébastien

    1. You have access
      Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
  3. Argikar, Upendra A.

    1. You have access
      Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
  4. Atwell, Graham J.

    1. You have access
      Metabolism and Excretion of the Novel Bioreductive Prodrug PR-104 in Mice, Rats, Dogs, and Humans
      Yongchuan Gu, Graham J. Atwell and William R. Wilson
      Drug Metabolism and Disposition March 2010, 38 (3) 498-508; DOI: https://doi.org/10.1124/dmd.109.030973

B

  1. Baeschlin, Daniel

    1. You have access
      Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
  2. Balliet, Rene M.

    1. You have access
      UDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer Susceptibility
      Rene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip Lazarus
      Drug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569
  3. Bergman, Arthur J.

    1. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  4. Biddle, Zachary

    1. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  5. Bischoff, Daniel

    1. You have access
      Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombe
      Călin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias Bureik
      Drug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965
  6. Boisvert, Caroline

    1. You have access
      Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
  7. Bradley, Scott

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
  8. Braun, Matthew P.

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  9. Buchheit, Daniela

    1. You have access
      Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombe
      Călin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias Bureik
      Drug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965
  10. Bureik, Matthias

    1. You have access
      Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombe
      Călin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias Bureik
      Drug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965

C

  1. Cai, Hong

    1. You have access
      In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
  2. Camus, Sandrine

    1. You have access
      Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
  3. Cavaco, Isa

    1. You have access
      New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
  4. Chen, Feng

    1. You have access
      Comment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng Chen
      Drug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825
  5. Chen, Gang

    1. You have access
      UDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer Susceptibility
      Rene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip Lazarus
      Drug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569
  6. Chen, Mei

    1. You have access
      Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
      Mei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. Williams
      Drug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900
  7. Chen, Qing

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
  8. Chen, Shiang-yuan

    1. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  9. Chesné, Christophe

    1. You have access
      Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
  10. Chong, Saeho

    1. You have access
      In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
  11. Court, Michael H.

    1. You have access
      Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138

D

  1. Dani, Mélina

    1. You have access
      Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
  2. Darnell, Malin

    1. You have access
      Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
  3. Dean, Dennis C.

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  4. Dellinger, Ryan W.

    1. You have access
      UDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer Susceptibility
      Rene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip Lazarus
      Drug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569
  5. Discenza, L.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  6. Doss, George

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
  7. Drăgan, Călin-Aurel

    1. You have access
      Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombe
      Călin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias Bureik
      Drug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965
  8. Dru, James

    1. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

E

  1. Ebner, Thomas

    1. You have access
      Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombe
      Călin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias Bureik
      Drug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965
  2. Ellsworth, B. A.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

F

  1. Feenstra, Kenneth L.

    1. You have access
      Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
  2. Felmlee, Melanie A.

    1. You have access
      Monocarboxylate Transporter-Mediated Transport of γ-Hydroxybutyric Acid in Human Intestinal Caco-2 Cells
      Wing Ki Lam, Melanie A. Felmlee and Marilyn E. Morris
      Drug Metabolism and Disposition March 2010, 38 (3) 441-447; DOI: https://doi.org/10.1124/dmd.109.030775
  3. Ferreira, Suzie

    1. You have access
      Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
  4. Finel, Moshe

    1. You have access
      Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
  5. Frost, Charles A.

    1. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  6. Fukamizu, Akiyoshi

    1. You have access
      Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668

G

  1. Gagne, Jason

    1. You have access
      Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
  2. Gendrano, Isaias Noel

    1. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  3. Goosen, Theunis C.

    1. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  4. Graves, Mark W.

    1. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  5. Griffith, W. Humphreys

    1. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  6. Grossman, Scott J.

    1. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  7. Gu, Yongchuan

    1. You have access
      Metabolism and Excretion of the Novel Bioreductive Prodrug PR-104 in Mice, Rats, Dogs, and Humans
      Yongchuan Gu, Graham J. Atwell and William R. Wilson
      Drug Metabolism and Disposition March 2010, 38 (3) 498-508; DOI: https://doi.org/10.1124/dmd.109.030973
  8. Guguen-Guillouzo, Christiane

    1. You have access
      Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
  9. Guillouzo, André

    1. You have access
      Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
  10. Gunduz, Mithat

    1. You have access
      Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650

H

  1. Harper, Timothy W.

    1. You have access
      In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
  2. Harriman, Shawn

    1. You have access
      Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
  3. Hartmann, Georgy

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  4. He, Kan

    1. You have access
      In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
    2. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  5. Hidalgo, Ismael J.

    1. You have access
      Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
  6. Ho, Jonathan Z.

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  7. Hofmann, Yvonne

    1. You have access
      New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
  8. Höglund, Camilla

    1. You have access
      Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
  9. Hosagrahara, Vinayak

    1. You have access
      Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650
  10. Howe, David

    1. You have access
      Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
      Mei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. Williams
      Drug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900
  11. Hsueh, Mei-Mann

    1. You have access
      In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
  12. Hu, Zhe-Yi

    1. You have access
      Comment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng Chen
      Drug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825
  13. Humphreys, W. G.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

I

  1. Ingelman-Sundberg, Magnus

    1. You have access
      New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405

J

  1. Jensen, Klaus Gjervig

    1. You have access
      Identification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based Simulator
      Jakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian Linnet
      Drug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551
  2. Jiang, Rong-Rong

    1. You have access
      Comment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng Chen
      Drug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825
  3. Johnson, Stephen

    1. You have access
      In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
  4. Jones, Allen N.

    1. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  5. Jornil, Jakob

    1. You have access
      Identification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based Simulator
      Jakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian Linnet
      Drug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551

K

  1. Kadowaki, Tadashi

    1. You have access
      Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668
  2. Karanam, Bindhu

    1. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  3. Karlsson, Johan E.

    1. You have access
      Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
  4. Kasichayanula, S.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  5. Kerr, Stephen

    1. You have access
      Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
      Mei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. Williams
      Drug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900
  6. Khanna, A.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  7. Komoroski, B.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  8. Koplowitz, B.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  9. Krishna, Rajesh

    1. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  10. Kumar, Sanjeev

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  11. Kurkela, Mika

    1. You have access
      Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
  12. Kusano, Kazutomi

    1. You have access
      Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668

L

  1. Lahoz, Agustin

    1. You have access
      Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
  2. Lam, Wing Ki

    1. You have access
      Monocarboxylate Transporter-Mediated Transport of γ-Hydroxybutyric Acid in Human Intestinal Caco-2 Cells
      Wing Ki Lam, Melanie A. Felmlee and Marilyn E. Morris
      Drug Metabolism and Disposition March 2010, 38 (3) 441-447; DOI: https://doi.org/10.1124/dmd.109.030775
  3. Landman, Ellie

    1. You have access
      New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
  4. Larsen, Frank

    1. You have access
      Identification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based Simulator
      Jakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian Linnet
      Drug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551
  5. Lazarus, Philip

    1. You have access
      UDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer Susceptibility
      Rene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip Lazarus
      Drug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569
  6. Leblond, Francois A.

    1. You have access
      Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
  7. LeDuc, Barbara

    1. You have access
      Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
      Mei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. Williams
      Drug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900
  8. Lefrançois, Stéphane

    1. You have access
      Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
  9. Li, Jibin

    1. You have access
      Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
  10. Li, Ruoya

    1. You have access
      Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
  11. Li, W.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  12. Linnet, Kristian

    1. You have access
      Identification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based Simulator
      Jakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian Linnet
      Drug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551
  13. Locuson, Charles W.

    1. You have access
      Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
  14. Luo, Gang

    1. You have access
      In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260

M

  1. Ma, Li

    1. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  2. Manevski, Nenad

    1. You have access
      Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
  3. Mauriala, Timo

    1. You have access
      Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
  4. Maxwell, Brad D.

    1. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  5. Meng, W.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  6. Michaud, Josée

    1. You have access
      Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
  7. Mills, Beth Miskimins

    1. You have access
      Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
  8. Mkrtchian, Souren

    1. You have access
      New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
  9. Morris, Marilyn E.

    1. You have access
      Monocarboxylate Transporter-Mediated Transport of γ-Hydroxybutyric Acid in Human Intestinal Caco-2 Cells
      Wing Ki Lam, Melanie A. Felmlee and Marilyn E. Morris
      Drug Metabolism and Disposition March 2010, 38 (3) 441-447; DOI: https://doi.org/10.1124/dmd.109.030775
  10. Mwinyi, Jessica

    1. You have access
      New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405

N

  1. Naud, Judith

    1. You have access
      Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991
  2. Nekvindová, Jana

    1. You have access
      New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405

O

  1. Obermeier, M.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  2. Okamoto, Kiyoshi

    1. You have access
      Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668
  3. Owen, Albert

    1. You have access
      Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967

P

  1. Pang, K. Sandy

    1. You have access
      Response to Letter to the Editor on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition March 2010, 38 (3) 536-537; DOI: https://doi.org/10.1124/dmd.109.031195
  2. Pedersen, Rasmus Steen

    1. You have access
      New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405
  3. Pereira, Antonio

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
  4. Picazo, Laura

    1. You have access
      Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
  5. Pichette, Vincent

    1. You have access
      Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991

R

  1. Raghavan, Nirmala

    1. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  2. Remmel, Rory P.

    1. You have access
      Glucuronidation of Dihydrotestosterone and trans-Androsterone by Recombinant UDP-Glucuronosyltransferase (UGT) 1A4: Evidence for Multiple UGT1A4 Aglycone Binding Sites
      Jin Zhou, Timothy S. Tracy and Rory P. Remmel
      Drug Metabolism and Disposition March 2010, 38 (3) 431-440; DOI: https://doi.org/10.1124/dmd.109.028712

S

  1. Staskiewicz, Steve J.

    1. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  2. Sugawara, Michiko

    1. You have access
      Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668
  3. Sun, Huadong

    1. You have access
      Response to Letter to the Editor on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition March 2010, 38 (3) 536-537; DOI: https://doi.org/10.1124/dmd.109.031195

T

  1. Tan, Eugene Y.

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  2. Tang, Wei

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
  3. Tolonen, Ari

    1. You have access
      Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197
  4. Tracy, Timothy S.

    1. You have access
      Glucuronidation of Dihydrotestosterone and trans-Androsterone by Recombinant UDP-Glucuronosyltransferase (UGT) 1A4: Evidence for Multiple UGT1A4 Aglycone Binding Sites
      Jin Zhou, Timothy S. Tracy and Rory P. Remmel
      Drug Metabolism and Disposition March 2010, 38 (3) 431-440; DOI: https://doi.org/10.1124/dmd.109.028712
  5. Turpeinen, Miia

    1. You have access
      Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

U

  1. Uusitalo, Jouko

    1. You have access
      Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

W

  1. Wagner, John A.

    1. You have access
      Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704
  2. Walters, Rodney R.

    1. You have access
      Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
  3. Wang, Lifei

    1. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  4. Washburn, W.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  5. Whaley, J. M.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  6. White, Julie A.

    1. You have access
      Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
  7. Williams, David A.

    1. You have access
      Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
      Mei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. Williams
      Drug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900
  8. Wilson, William R.

    1. You have access
      Metabolism and Excretion of the Novel Bioreductive Prodrug PR-104 in Mice, Rats, Dogs, and Humans
      Yongchuan Gu, Graham J. Atwell and William R. Wilson
      Drug Metabolism and Disposition March 2010, 38 (3) 498-508; DOI: https://doi.org/10.1124/dmd.109.030973

X

  1. Xin, Baomin

    1. You have access
      In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260

Y

  1. Yang, Jun-Ling

    1. You have access
      Comment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng Chen
      Drug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825
  2. Yao, M.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
  3. Yao, Ming

    1. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  4. Yli-Kauhaluoma, Jari

    1. You have access
      Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138
  5. Yoshimura, Tsutomu

    1. You have access
      Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668

Z

  1. Zaya, Matthew J.

    1. You have access
      Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429
  2. Zhang, Andy Shiqiang

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
  3. Zhang, Donglu

    1. You have access
      In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694
  4. Zhang, Wei

    1. You have access
      Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967
  5. Zhao, Yuan-Sheng

    1. You have access
      Comment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng Chen
      Drug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825
  6. Zheng, Joanna

    1. You have access
      In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
  7. Zhou, Jin

    1. You have access
      Glucuronidation of Dihydrotestosterone and trans-Androsterone by Recombinant UDP-Glucuronosyltransferase (UGT) 1A4: Evidence for Multiple UGT1A4 Aglycone Binding Sites
      Jin Zhou, Timothy S. Tracy and Rory P. Remmel
      Drug Metabolism and Disposition March 2010, 38 (3) 431-440; DOI: https://doi.org/10.1124/dmd.109.028712
  8. Zhu, M.

    1. You have access
      In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
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Drug Metabolism and Disposition: 38 (3)
Drug Metabolism and Disposition
Vol. 38, Issue 3
1 Mar 2010
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
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ISSN 1521-009X (Online)

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