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Index by author

March 01, 2010; Volume 38,Issue 3

A

  1. Andersson, Tommy B.

    1. Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967

  2. Anthérieu, Sébastien

    1. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

  3. Argikar, Upendra A.

    1. Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650

  4. Atwell, Graham J.

    1. Metabolism and Excretion of the Novel Bioreductive Prodrug PR-104 in Mice, Rats, Dogs, and Humans
      Yongchuan Gu, Graham J. Atwell and William R. Wilson
      Drug Metabolism and Disposition March 2010, 38 (3) 498-508; DOI: https://doi.org/10.1124/dmd.109.030973

B

  1. Baeschlin, Daniel

    1. Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650

  2. Balliet, Rene M.

    1. UDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer Susceptibility
      Rene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip Lazarus
      Drug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569

  3. Bergman, Arthur J.

    1. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  4. Biddle, Zachary

    1. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  5. Bischoff, Daniel

    1. Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombe
      Călin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias Bureik
      Drug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965

  6. Boisvert, Caroline

    1. Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991

  7. Bradley, Scott

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696

  8. Braun, Matthew P.

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  9. Buchheit, Daniela

    1. Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombe
      Călin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias Bureik
      Drug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965

  10. Bureik, Matthias

    1. Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombe
      Călin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias Bureik
      Drug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965

C

  1. Cai, Hong

    1. In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260

  2. Camus, Sandrine

    1. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

  3. Cavaco, Isa

    1. New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405

  4. Chen, Feng

    1. Comment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng Chen
      Drug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825

  5. Chen, Gang

    1. UDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer Susceptibility
      Rene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip Lazarus
      Drug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569

  6. Chen, Mei

    1. Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
      Mei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. Williams
      Drug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900

  7. Chen, Qing

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696

  8. Chen, Shiang-yuan

    1. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  9. Chesné, Christophe

    1. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

  10. Chong, Saeho

    1. In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260

  11. Court, Michael H.

    1. Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138

D

  1. Dani, Mélina

    1. Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991

  2. Darnell, Malin

    1. Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967

  3. Dean, Dennis C.

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  4. Dellinger, Ryan W.

    1. UDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer Susceptibility
      Rene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip Lazarus
      Drug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569

  5. Discenza, L.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

  6. Doss, George

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696

  7. Drăgan, Călin-Aurel

    1. Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombe
      Călin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias Bureik
      Drug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965

  8. Dru, James

    1. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

E

  1. Ebner, Thomas

    1. Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fission Yeast Schizosaccharomyces pombe
      Călin-Aurel Drăgan, Daniela Buchheit, Daniel Bischoff, Thomas Ebner and Matthias Bureik
      Drug Metabolism and Disposition March 2010, 38 (3) 509-515; DOI: https://doi.org/10.1124/dmd.109.030965

  2. Ellsworth, B. A.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

F

  1. Feenstra, Kenneth L.

    1. Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429

  2. Felmlee, Melanie A.

    1. Monocarboxylate Transporter-Mediated Transport of γ-Hydroxybutyric Acid in Human Intestinal Caco-2 Cells
      Wing Ki Lam, Melanie A. Felmlee and Marilyn E. Morris
      Drug Metabolism and Disposition March 2010, 38 (3) 441-447; DOI: https://doi.org/10.1124/dmd.109.030775

  3. Ferreira, Suzie

    1. Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650

  4. Finel, Moshe

    1. Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138

  5. Frost, Charles A.

    1. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  6. Fukamizu, Akiyoshi

    1. Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668

G

  1. Gagne, Jason

    1. Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429

  2. Gendrano, Isaias Noel

    1. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  3. Goosen, Theunis C.

    1. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  4. Graves, Mark W.

    1. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  5. Griffith, W. Humphreys

    1. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  6. Grossman, Scott J.

    1. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  7. Gu, Yongchuan

    1. Metabolism and Excretion of the Novel Bioreductive Prodrug PR-104 in Mice, Rats, Dogs, and Humans
      Yongchuan Gu, Graham J. Atwell and William R. Wilson
      Drug Metabolism and Disposition March 2010, 38 (3) 498-508; DOI: https://doi.org/10.1124/dmd.109.030973

  8. Guguen-Guillouzo, Christiane

    1. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

  9. Guillouzo, André

    1. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

  10. Gunduz, Mithat

    1. Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650

H

  1. Harper, Timothy W.

    1. In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260

  2. Harriman, Shawn

    1. Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650

  3. Hartmann, Georgy

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  4. He, Kan

    1. In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260
    2. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  5. Hidalgo, Ismael J.

    1. Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967

  6. Ho, Jonathan Z.

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  7. Hofmann, Yvonne

    1. New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405

  8. Höglund, Camilla

    1. Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138

  9. Hosagrahara, Vinayak

    1. Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies
      Mithat Gunduz, Upendra A. Argikar, Daniel Baeschlin, Suzie Ferreira, Vinayak Hosagrahara and Shawn Harriman
      Drug Metabolism and Disposition March 2010, 38 (3) 361-367; DOI: https://doi.org/10.1124/dmd.109.030650

  10. Howe, David

    1. Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
      Mei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. Williams
      Drug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900

  11. Hsueh, Mei-Mann

    1. In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260

  12. Hu, Zhe-Yi

    1. Comment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng Chen
      Drug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825

  13. Humphreys, W. G.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

I

  1. Ingelman-Sundberg, Magnus

    1. New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405

J

  1. Jensen, Klaus Gjervig

    1. Identification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based Simulator
      Jakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian Linnet
      Drug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551

  2. Jiang, Rong-Rong

    1. Comment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng Chen
      Drug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825

  3. Johnson, Stephen

    1. In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260

  4. Jones, Allen N.

    1. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  5. Jornil, Jakob

    1. Identification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based Simulator
      Jakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian Linnet
      Drug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551

K

  1. Kadowaki, Tadashi

    1. Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668

  2. Karanam, Bindhu

    1. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  3. Karlsson, Johan E.

    1. Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967

  4. Kasichayanula, S.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

  5. Kerr, Stephen

    1. Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
      Mei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. Williams
      Drug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900

  6. Khanna, A.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

  7. Komoroski, B.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

  8. Koplowitz, B.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

  9. Krishna, Rajesh

    1. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  10. Kumar, Sanjeev

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  11. Kurkela, Mika

    1. Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138

  12. Kusano, Kazutomi

    1. Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668

L

  1. Lahoz, Agustin

    1. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

  2. Lam, Wing Ki

    1. Monocarboxylate Transporter-Mediated Transport of γ-Hydroxybutyric Acid in Human Intestinal Caco-2 Cells
      Wing Ki Lam, Melanie A. Felmlee and Marilyn E. Morris
      Drug Metabolism and Disposition March 2010, 38 (3) 441-447; DOI: https://doi.org/10.1124/dmd.109.030775

  3. Landman, Ellie

    1. New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405

  4. Larsen, Frank

    1. Identification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based Simulator
      Jakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian Linnet
      Drug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551

  5. Lazarus, Philip

    1. UDP-Glucuronosyltransferase 1A10: Activity against the Tobacco-Specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a Potential Role for a Novel UGT1A10 Promoter Deletion Polymorphism in Cancer Susceptibility
      Rene M. Balliet, Gang Chen, Ryan W. Dellinger and Philip Lazarus
      Drug Metabolism and Disposition March 2010, 38 (3) 484-490; DOI: https://doi.org/10.1124/dmd.109.030569

  6. Leblond, Francois A.

    1. Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991

  7. LeDuc, Barbara

    1. Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
      Mei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. Williams
      Drug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900

  8. Lefrançois, Stéphane

    1. Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991

  9. Li, Jibin

    1. Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967

  10. Li, Ruoya

    1. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

  11. Li, W.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

  12. Linnet, Kristian

    1. Identification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based Simulator
      Jakob Jornil, Klaus Gjervig Jensen, Frank Larsen and Kristian Linnet
      Drug Metabolism and Disposition March 2010, 38 (3) 376-385; DOI: https://doi.org/10.1124/dmd.109.030551

  13. Locuson, Charles W.

    1. Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429

  14. Luo, Gang

    1. In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260

M

  1. Ma, Li

    1. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  2. Manevski, Nenad

    1. Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138

  3. Mauriala, Timo

    1. Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138

  4. Maxwell, Brad D.

    1. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  5. Meng, W.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

  6. Michaud, Josée

    1. Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991

  7. Mills, Beth Miskimins

    1. Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429

  8. Mkrtchian, Souren

    1. New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405

  9. Morris, Marilyn E.

    1. Monocarboxylate Transporter-Mediated Transport of γ-Hydroxybutyric Acid in Human Intestinal Caco-2 Cells
      Wing Ki Lam, Melanie A. Felmlee and Marilyn E. Morris
      Drug Metabolism and Disposition March 2010, 38 (3) 441-447; DOI: https://doi.org/10.1124/dmd.109.030775

  10. Mwinyi, Jessica

    1. New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405

N

  1. Naud, Judith

    1. Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991

  2. Nekvindová, Jana

    1. New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405

O

  1. Obermeier, M.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

  2. Okamoto, Kiyoshi

    1. Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668

  3. Owen, Albert

    1. Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967

P

  1. Pang, K. Sandy

    1. Response to Letter to the Editor on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition March 2010, 38 (3) 536-537; DOI: https://doi.org/10.1124/dmd.109.031195

  2. Pedersen, Rasmus Steen

    1. New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
      Jessica Mwinyi, Jana Nekvindová, Isa Cavaco, Yvonne Hofmann, Rasmus Steen Pedersen, Ellie Landman, Souren Mkrtchian and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition March 2010, 38 (3) 415-421; DOI: https://doi.org/10.1124/dmd.109.029405

  3. Pereira, Antonio

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696

  4. Picazo, Laura

    1. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

  5. Pichette, Vincent

    1. Down-Regulation of Liver Drug-Metabolizing Enzymes in a Murine Model of Chronic Renal Failure
      Mélina Dani, Caroline Boisvert, Josée Michaud, Judith Naud, Stéphane Lefrançois, Francois A. Leblond and Vincent Pichette
      Drug Metabolism and Disposition March 2010, 38 (3) 357-360; DOI: https://doi.org/10.1124/dmd.109.029991

R

  1. Raghavan, Nirmala

    1. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  2. Remmel, Rory P.

    1. Glucuronidation of Dihydrotestosterone and trans-Androsterone by Recombinant UDP-Glucuronosyltransferase (UGT) 1A4: Evidence for Multiple UGT1A4 Aglycone Binding Sites
      Jin Zhou, Timothy S. Tracy and Rory P. Remmel
      Drug Metabolism and Disposition March 2010, 38 (3) 431-440; DOI: https://doi.org/10.1124/dmd.109.028712

S

  1. Staskiewicz, Steve J.

    1. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  2. Sugawara, Michiko

    1. Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668

  3. Sun, Huadong

    1. Response to Letter to the Editor on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition March 2010, 38 (3) 536-537; DOI: https://doi.org/10.1124/dmd.109.031195

T

  1. Tan, Eugene Y.

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696
    2. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  2. Tang, Wei

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696

  3. Tolonen, Ari

    1. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

  4. Tracy, Timothy S.

    1. Glucuronidation of Dihydrotestosterone and trans-Androsterone by Recombinant UDP-Glucuronosyltransferase (UGT) 1A4: Evidence for Multiple UGT1A4 Aglycone Binding Sites
      Jin Zhou, Timothy S. Tracy and Rory P. Remmel
      Drug Metabolism and Disposition March 2010, 38 (3) 431-440; DOI: https://doi.org/10.1124/dmd.109.028712

  5. Turpeinen, Miia

    1. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

U

  1. Uusitalo, Jouko

    1. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
      Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Sandrine Camus, Agustin Lahoz, Laura Picazo, Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition March 2010, 38 (3) 516-525; DOI: https://doi.org/10.1124/dmd.109.030197

W

  1. Wagner, John A.

    1. Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans
      Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann, Zachary Biddle, Arthur J. Bergman, James Dru, Jonathan Z. Ho, Allen N. Jones, Steve J. Staskiewicz, Matthew P. Braun, Bindhu Karanam, Dennis C. Dean, Isaias Noel Gendrano, Mark W. Graves, John A. Wagner and Rajesh Krishna
      Drug Metabolism and Disposition March 2010, 38 (3) 474-483; DOI: https://doi.org/10.1124/dmd.109.028704

  2. Walters, Rodney R.

    1. Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429

  3. Wang, Lifei

    1. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  4. Washburn, W.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

  5. Whaley, J. M.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

  6. White, Julie A.

    1. Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429

  7. Williams, David A.

    1. Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
      Mei Chen, Barbara LeDuc, Stephen Kerr, David Howe and David A. Williams
      Drug Metabolism and Disposition March 2010, 38 (3) 368-375; DOI: https://doi.org/10.1124/dmd.109.029900

  8. Wilson, William R.

    1. Metabolism and Excretion of the Novel Bioreductive Prodrug PR-104 in Mice, Rats, Dogs, and Humans
      Yongchuan Gu, Graham J. Atwell and William R. Wilson
      Drug Metabolism and Disposition March 2010, 38 (3) 498-508; DOI: https://doi.org/10.1124/dmd.109.030973

X

  1. Xin, Baomin

    1. In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260

Y

  1. Yang, Jun-Ling

    1. Comment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng Chen
      Drug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825

  2. Yao, M.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165

  3. Yao, Ming

    1. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  4. Yli-Kauhaluoma, Jari

    1. Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-Glucuronosyltransferases
      Nenad Manevski, Mika Kurkela, Camilla Höglund, Timo Mauriala, Michael H. Court, Jari Yli-Kauhaluoma and Moshe Finel
      Drug Metabolism and Disposition March 2010, 38 (3) 386-395; DOI: https://doi.org/10.1124/dmd.109.031138

  5. Yoshimura, Tsutomu

    1. Expressions of Cytochrome P450, UDP-Glucuronosyltranferase, and Transporter Genes in Monolayer Carcinoma Cells Change in Subcutaneous Tumors Grown As Xenografts in Immunodeficient Nude Mice
      Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu and Tsutomu Yoshimura
      Drug Metabolism and Disposition March 2010, 38 (3) 526-533; DOI: https://doi.org/10.1124/dmd.109.030668

Z

  1. Zaya, Matthew J.

    1. Current Cytochrome P450 Phenotyping Methods Applied to Metabolic Drug-Drug Interaction Prediction in Dogs
      Beth Miskimins Mills, Matthew J. Zaya, Rodney R. Walters, Kenneth L. Feenstra, Julie A. White, Jason Gagne and Charles W. Locuson
      Drug Metabolism and Disposition March 2010, 38 (3) 396-404; DOI: https://doi.org/10.1124/dmd.109.030429

  2. Zhang, Andy Shiqiang

    1. Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
      Eugene Y. Tan, Georgy Hartmann, Qing Chen, Antonio Pereira, Scott Bradley, George Doss, Andy Shiqiang Zhang, Jonathan Z. Ho, Matthew P. Braun, Dennis C. Dean, Wei Tang and Sanjeev Kumar
      Drug Metabolism and Disposition March 2010, 38 (3) 459-473; DOI: https://doi.org/10.1124/dmd.109.028696

  3. Zhang, Donglu

    1. In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
      Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Charles A. Frost, Brad D. Maxwell, Shiang-yuan Chen, Kan He, Theunis C. Goosen, W. Humphreys Griffith and Scott J. Grossman
      Drug Metabolism and Disposition March 2010, 38 (3) 448-458; DOI: https://doi.org/10.1124/dmd.109.029694

  4. Zhang, Wei

    1. Investigation of the Involvement of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 in the Efflux of Ximelagatran and Its Metabolites by Using Short Hairpin RNA Knockdown in Caco-2 Cells
      Malin Darnell, Johan E. Karlsson, Albert Owen, Ismael J. Hidalgo, Jibin Li, Wei Zhang and Tommy B. Andersson
      Drug Metabolism and Disposition March 2010, 38 (3) 491-497; DOI: https://doi.org/10.1124/dmd.109.029967

  5. Zhao, Yuan-Sheng

    1. Comment on “Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study”
      Yuan-Sheng Zhao, Zhe-Yi Hu, Rong-Rong Jiang, Jun-Ling Yang and Feng Chen
      Drug Metabolism and Disposition March 2010, 38 (3) 534-535; DOI: https://doi.org/10.1124/dmd.109.030825

  6. Zheng, Joanna

    1. In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
      Gang Luo, Stephen Johnson, Mei-Mann Hsueh, Joanna Zheng, Hong Cai, Baomin Xin, Saeho Chong, Kan He and Timothy W. Harper
      Drug Metabolism and Disposition March 2010, 38 (3) 422-430; DOI: https://doi.org/10.1124/dmd.108.026260

  7. Zhou, Jin

    1. Glucuronidation of Dihydrotestosterone and trans-Androsterone by Recombinant UDP-Glucuronosyltransferase (UGT) 1A4: Evidence for Multiple UGT1A4 Aglycone Binding Sites
      Jin Zhou, Timothy S. Tracy and Rory P. Remmel
      Drug Metabolism and Disposition March 2010, 38 (3) 431-440; DOI: https://doi.org/10.1124/dmd.109.028712

  8. Zhu, M.

    1. In Vitro Characterization and Pharmacokinetics of Dapagliflozin (BMS-512148), a Potent Sodium-Glucose Cotransporter Type II Inhibitor, in Animals and Humans
      M. Obermeier, M. Yao, A. Khanna, B. Koplowitz, M. Zhu, W. Li, B. Komoroski, S. Kasichayanula, L. Discenza, W. Washburn, W. Meng, B. A. Ellsworth, J. M. Whaley and W. G. Humphreys
      Drug Metabolism and Disposition March 2010, 38 (3) 405-414; DOI: https://doi.org/10.1124/dmd.109.029165
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