Table of Contents

Articles

• You have access

  Molecular Cloning of the Baboon UDP-Glucuronosyltransferase 2B Gene Family and Their Activity in Conjugating Morphine

  Kirsten Abildskov, Piper Weldy and Marianne Garland

  Drug Metabolism and Disposition April 2010, 38 (4) 545-553; DOI: https://doi.org/10.1124/dmd.109.030635
• You have access

  Disposition and Metabolism of Semagacestat, a γ-Secretase Inhibitor, in Humans

  Ping Yi, Chad Hadden, Palaniappan Kulanthaivel, Nathan Calvert, William Annes, Thomas Brown, Robert J. Barbuch, Archana Chaudhary, Mosun A. Ayan-Oshodi and Barbara J. Ring

  Drug Metabolism and Disposition April 2010, 38 (4) 554-565; DOI: https://doi.org/10.1124/dmd.109.030841
• You have access

  Monoclonal Antibody-Glial-Derived Neurotrophic Factor Fusion Protein Penetrates the Blood-Brain Barrier in the Mouse

  Qing-Hui Zhou, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui and William M. Pardridge

  Drug Metabolism and Disposition April 2010, 38 (4) 566-572; DOI: https://doi.org/10.1124/dmd.109.031534
• You have access

  Role of P-Glycoprotein in the Disposition of Macrocyclic Lactones: A Comparison between Ivermectin, Eprinomectin, and Moxidectin in Mice

  Solange Kiki-Mvouaka, Cécile Ménez, Christiane Borin, Faouri Lyazrhi, Magali Foucaud-Vignault, Jacques Dupuy, Xavier Collet, Michel Alvinerie and Anne Lespine

  Drug Metabolism and Disposition April 2010, 38 (4) 573-580; DOI: https://doi.org/10.1124/dmd.109.030700
• You have access

  Species Differences in the Formation of Vabicaserin Carbamoyl Glucuronide

  Zeen Tong, Appavu Chandrasekaran, William DeMaio, Ronald Jordan, Hongshan Li, Robin Moore, Nagaraju Poola, Peter Burghart, Theresa Hultin and JoAnn Scatina

  Drug Metabolism and Disposition April 2010, 38 (4) 581-590; DOI: https://doi.org/10.1124/dmd.109.028639
• You have access

  Hepatocyte Nuclear Factor 4α Regulates Rifampicin-Mediated Induction of CYP2C Genes in Primary Cultures of Human Hepatocytes

  Ritu Rana, Yuping Chen, Stephen S. Ferguson, Grace E. Kissling, Sailesh Surapureddi and Joyce A. Goldstein

  Drug Metabolism and Disposition April 2010, 38 (4) 591-599; DOI: https://doi.org/10.1124/dmd.109.030387
• You have access

  Pharmacokinetics of Humanized Monoclonal Anti-Tumor Necrosis Factor-α Antibody and Its Neonatal Fc Receptor Variants in Mice and Cynomolgus Monkeys

  Rong Deng, Kelly M. Loyet, Samantha Lien, Suhasini Iyer, Laura E. DeForge, Frank-Peter Theil, Henry B. Lowman, Paul J. Fielder and Saileta Prabhu

  Drug Metabolism and Disposition April 2010, 38 (4) 600-605; DOI: https://doi.org/10.1124/dmd.109.031310
• You have access

  Metabolism of Intravenous Methylnaltrexone in Mice, Rats, Dogs, and Humans

  Appavu Chandrasekaran, Zeen Tong, Hongshan Li, John C. L. Erve, William DeMaio, Igor Goljer, Oliver McConnell, Yakov Rotshteyn, Theresa Hultin, Rasmy Talaat and JoAnn Scatina

  Drug Metabolism and Disposition April 2010, 38 (4) 606-616; DOI: https://doi.org/10.1124/dmd.109.031179
• You have access

  Phase II Metabolism of Hesperetin by Individual UDP-Glucuronosyltransferases and Sulfotransferases and Rat and Human Tissue Samples

  Walter Brand, Marelle G. Boersma, Hanneke Bik, Elisabeth F. Hoek-van den Hil, Jacques Vervoort, Denis Barron, Walter Meinl, Hansruedi Glatt, Gary Williamson, Peter J. van Bladeren and Ivonne M. C. M. Rietjens

  Drug Metabolism and Disposition April 2010, 38 (4) 617-625; DOI: https://doi.org/10.1124/dmd.109.031047
• You have access

  Identification of the UDP-Glucuronosyltransferase Isozyme Involved in Senecionine Glucuronidation in Human Liver Microsomes

  Yu-Qi He, Yong Liu, Bin-Feng Zhang, Hui-Xin Liu, Yan-Liu Lu, Li Yang, Ai-zhen Xiong, Ling-Ling Xu, Chang-Hong Wang, Ling Yang and Zheng-Tao Wang

  Drug Metabolism and Disposition April 2010, 38 (4) 626-634; DOI: https://doi.org/10.1124/dmd.109.030460
• You have access

  Absorption, Distribution, and Biliary Excretion of Cafestol, a Potent Cholesterol-Elevating Compound in Unfiltered Coffees, in Mice

  S. T. J. van Cruchten, D. R. de Waart, C. Kunne, G. J. E. J. Hooiveld, M. V. Boekschoten, M. B. Katan, R. P. J. Oude Elferink and R. F. Witkamp

  Drug Metabolism and Disposition April 2010, 38 (4) 635-640; DOI: https://doi.org/10.1124/dmd.109.030213
• You have access

  Cross-Species Comparison of the Metabolism and Excretion of Zoniporide: Contribution of Aldehyde Oxidase to Interspecies Differences

  Deepak Dalvie, Chenghong Zhang, Weichao Chen, Teresa Smolarek, R. Scott Obach and Cho-Ming Loi

  Drug Metabolism and Disposition April 2010, 38 (4) 641-654; DOI: https://doi.org/10.1124/dmd.109.030783
• You have access

  Disposition of [1′-¹⁴C]Stavudine after Oral Administration to Humans

  Lian Zhou, Sanjeev Kaul, Peggy Liu-Kreyche, Scott B. Tran, Robert R. Espina, Bethanne M. Warrack, Vikram A. Roongta and Ramaswamy A. Iyer

  Drug Metabolism and Disposition April 2010, 38 (4) 655-666; DOI: https://doi.org/10.1124/dmd.109.030239
• You have access

  The Metabolism and Disposition of the Oral Dipeptidyl Peptidase-4 Inhibitor, Linagliptin, in Humans

  Stefan Blech, Eva Ludwig-Schwellinger, Eva Ulrike Gräfe-Mody, Barbara Withopf and Klaus Wagner

  Drug Metabolism and Disposition April 2010, 38 (4) 667-678; DOI: https://doi.org/10.1124/dmd.109.031476
• You have access

  Xenobiotic-Metabolizing Cytochromes P450 in Human White Adipose Tissue: Expression and Induction

  Sandrine Ellero, Ghassan Chakhtoura, Corinne Barreau, Sophie Langouët, Chantal Benelli, Luc Penicaud, Philippe Beaune and Isabelle de Waziers

  Drug Metabolism and Disposition April 2010, 38 (4) 679-686; DOI: https://doi.org/10.1124/dmd.109.029249
• You have access

  How Many and Which Amino Acids Are Responsible for the Large Activity Differences between the Highly Homologous UDP-Glucuronosyltransferases (UGT) 1A9 and UGT1A10?

  Katriina Itäaho, Liisa Laakkonen and Moshe Finel

  Drug Metabolism and Disposition April 2010, 38 (4) 687-696; DOI: https://doi.org/10.1124/dmd.109.031229
• You have access

  Polychlorinated Biphenyl-Mediated Decrease in Serum Thyroxine Level in Rodents

  Yoshihisa Kato, Koichi Haraguchi, Yuriko Ito, Aki Fujii, Tomoaki Yamazaki, Tetsuya Endo, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa

  Drug Metabolism and Disposition April 2010, 38 (4) 697-704; DOI: https://doi.org/10.1124/dmd.109.031153
• You have access

  High-Activity P-Glycoprotein, Multidrug Resistance Protein 2, and Breast Cancer Resistance Protein Membrane Vesicles Prepared from Transiently Transfected Human Embryonic Kidney 293-Epstein-Barr Virus Nuclear Antigen Cells

  Johan E. Karlsson, Catherine Heddle, Aleksei Rozkov, Joke Rotticci-Mulder, Ola Tuvesson, Constanze Hilgendorf and Tommy B. Andersson

  Drug Metabolism and Disposition April 2010, 38 (4) 705-714; DOI: https://doi.org/10.1124/dmd.109.028886
• You have access

  Evaluation of 4′,6-Diamidino-2-phenylindole as a Fluorescent Probe Substrate for Rapid Assays of the Functionality of Human Multidrug and Toxin Extrusion Proteins

  Tomoya Yasujima, Kin-ya Ohta, Katsuhisa Inoue, Munenori Ishimaru and Hiroaki Yuasa

  Drug Metabolism and Disposition April 2010, 38 (4) 715-721; DOI: https://doi.org/10.1124/dmd.109.030221