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Research ArticleArticle

Hepatocyte Nuclear Factor 4α Regulates Rifampicin-Mediated Induction of CYP2C Genes in Primary Cultures of Human Hepatocytes

Ritu Rana, Yuping Chen, Stephen S. Ferguson, Grace E. Kissling, Sailesh Surapureddi and Joyce A. Goldstein
Drug Metabolism and Disposition April 2010, 38 (4) 591-599; DOI: https://doi.org/10.1124/dmd.109.030387

Article Information

vol. 38 no. 4 591-599
DOI 
https://doi.org/10.1124/dmd.109.030387
PubMed 
20086032
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 23, 2009
  • Accepted January 15, 2010
  • Published online March 16, 2010.

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Copyright & Usage 
U.S. Government work not protected by U.S. copyright

Author Information

  1. Ritu Rana,
  2. Yuping Chen,
  3. Stephen S. Ferguson,
  4. Grace E. Kissling,
  5. Sailesh Surapureddi and
  6. Joyce A. Goldstein
  1. Human Metabolism Section, Laboratory of Pharmacology (R.R., Y.C., S.S., J.A.G.) and Biostatistics Branch (G.E.K.), National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina; and Invitrogen Corporation/CellzDirect, Durham, North Carolina (S.S.F.)
  1. Address correspondence to:
    Dr. Joyce A. Goldstein, Laboratory of Pharmacology, National Institute of Environmental Health Sciences, P.O. Box 12233, Research Triangle Park, NC 27709. E-mail: goldste1{at}niehs.nih.gov

  1. R.R. and Y.C. contributed equally to this work.

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Research ArticleArticle

Hepatocyte Nuclear Factor 4α Regulates Rifampicin-Mediated Induction of CYP2C Genes in Primary Cultures of Human Hepatocytes

Ritu Rana, Yuping Chen, Stephen S. Ferguson, Grace E. Kissling, Sailesh Surapureddi and Joyce A. Goldstein
Drug Metabolism and Disposition April 1, 2010, 38 (4) 591-599; DOI: https://doi.org/10.1124/dmd.109.030387
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