Advertisement
Research ArticleArticle

Pharmacokinetics of Humanized Monoclonal Anti-Tumor Necrosis Factor-α Antibody and Its Neonatal Fc Receptor Variants in Mice and Cynomolgus Monkeys

Rong Deng, Kelly M. Loyet, Samantha Lien, Suhasini Iyer, Laura E. DeForge, Frank-Peter Theil, Henry B. Lowman, Paul J. Fielder and Saileta Prabhu
Drug Metabolism and Disposition April 2010, 38 (4) 600-605; DOI: https://doi.org/10.1124/dmd.109.031310

Article Information

vol. 38 no. 4 600-605
DOI 
https://doi.org/10.1124/dmd.109.031310
PubMed 
20071453
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received November 23, 2009
  • Accepted January 13, 2010
  • Published online March 16, 2010.

Article Versions

Copyright & Usage 
Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Rong Deng,
  2. Kelly M. Loyet,
  3. Samantha Lien,
  4. Suhasini Iyer,
  5. Laura E. DeForge,
  6. Frank-Peter Theil,
  7. Henry B. Lowman,
  8. Paul J. Fielder and
  9. Saileta Prabhu
  1. Department of Pharmacokinetic and Pharmacodynamic Sciences (R.D., S.I., F.-P.T., P.J.F., S.P.), Department of Assay and Automation Technology (K.M.L., L.E.D.), and Department of Antibody Engineering (S.L., H.B.L.), Genentech Inc., South San Francisco, California
  1. Address correspondence to:
    Dr. Rong Deng, Department of Pharmacokinetics and Pharmacodynamics Sciences, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080. E-mail deng.rong{at}gene.com
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: August 2017 to May 2023

AbstractFullPdf
Aug 201745619
Sep 201745030
Oct 201707322
Nov 201748423
Dec 201735424
Jan 201835214
Feb 201867325
Mar 201877627
Apr 201856224
May 201819218
Jun 201855123
Jul 201814516
Aug 201875825
Sep 201844419
Oct 2018146627
Nov 201885413
Dec 2018441812
Jan 201970153
Feb 20193888
Mar 2019641616
Apr 20191011418
May 201966119
Jun 2019481317
Jul 2019652221
Aug 20195598
Oct 201980913
Nov 201951147
Dec 20197067
Jan 20207266
Feb 202052179
Mar 2020671710
May 202071120
Jun 202041185
Jul 2020971518
Aug 2020241717
Sep 202039142
Oct 2020561918
Nov 20205385
Dec 20205497
Jan 202167133
Feb 2021681913
Mar 202164127
Apr 20213451
May 20212983
Jun 202141131
Jul 202144132
Aug 2021371612
Sep 20219799
Oct 20217791
Nov 20216443
Dec 20217353
Jan 2022611410
Feb 20226194
Mar 202280103
Apr 202285117
May 202272105
Jun 20226542
Jul 202292917
Aug 20228933
Sep 202255152
Oct 202291178
Nov 20225469
Dec 202243814
Jan 202312194
Feb 202398168
Mar 20239073
Apr 20236769
May 202337117

Back to top

In this issue

Download PDF
Article Alerts
Email Article
Citation Tools

Research ArticleArticle

Pharmacokinetics of Humanized Monoclonal Anti-Tumor Necrosis Factor-α Antibody and Its Neonatal Fc Receptor Variants in Mice and Cynomolgus Monkeys

Rong Deng, Kelly M. Loyet, Samantha Lien, Suhasini Iyer, Laura E. DeForge, Frank-Peter Theil, Henry B. Lowman, Paul J. Fielder and Saileta Prabhu
Drug Metabolism and Disposition April 1, 2010, 38 (4) 600-605; DOI: https://doi.org/10.1124/dmd.109.031310
Reddit logo Twitter logo Facebook logo Mendeley logo

Jump to section

Advertisement