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Research ArticleArticle

Phase II Metabolism of Hesperetin by Individual UDP-Glucuronosyltransferases and Sulfotransferases and Rat and Human Tissue Samples

Walter Brand, Marelle G. Boersma, Hanneke Bik, Elisabeth F. Hoek-van den Hil, Jacques Vervoort, Denis Barron, Walter Meinl, Hansruedi Glatt, Gary Williamson, Peter J. van Bladeren and Ivonne M. C. M. Rietjens
Drug Metabolism and Disposition April 2010, 38 (4) 617-625; DOI: https://doi.org/10.1124/dmd.109.031047
Walter Brand
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Marelle G. Boersma
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Hanneke Bik
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Elisabeth F. Hoek-van den Hil
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Jacques Vervoort
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Denis Barron
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Walter Meinl
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Hansruedi Glatt
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Gary Williamson
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Peter J. van Bladeren
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Ivonne M. C. M. Rietjens
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Article Information

vol. 38 no. 4 617-625
DOI 
https://doi.org/10.1124/dmd.109.031047
PubMed 
20056724

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received November 5, 2009
  • Accepted January 7, 2010
  • Published online March 16, 2010.

Article Versions

  • Earlier version (January 7, 2010 - 08:59).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Walter Brand,
  2. Marelle G. Boersma,
  3. Hanneke Bik,
  4. Elisabeth F. Hoek-van den Hil,
  5. Jacques Vervoort,
  6. Denis Barron,
  7. Walter Meinl,
  8. Hansruedi Glatt,
  9. Gary Williamson,
  10. Peter J. van Bladeren and
  11. Ivonne M. C. M. Rietjens
  1. Division of Toxicology, Wageningen University, Wageningen, The Netherlands (W.B., M.G.B., H.B., E.F.H.v.d.H., P.J.v.B., I.M.C.M.R.); Nestlé Research Center, Nestec Ltd., Lausanne, Switzerland (W.B., D.B., G.W., P.J.v.B.); Biqualys, Wageningen, The Netherlands (J.V.); Department of Nutritional Toxicology, German Institute of Human Nutrition, Potsdam-Rehbrücke, Nuthetal, Germany (W.M., H.G.); and School of Food Science and Nutrition, University of Leeds, Leeds, United Kingdom (G.W.)
  1. Address correspondence to:
    Walter Brand, Division of Toxicology, Wageningen University, P.O. Box 8000, 6700 EA Wageningen, The Netherlands. E-mail: walter.brand{at}wur.nl
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Drug Metabolism and Disposition: 38 (4)
Drug Metabolism and Disposition
Vol. 38, Issue 4
1 Apr 2010
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Research ArticleArticle

Phase II Metabolism of Hesperetin by Individual UDP-Glucuronosyltransferases and Sulfotransferases and Rat and Human Tissue Samples

Walter Brand, Marelle G. Boersma, Hanneke Bik, Elisabeth F. Hoek-van den Hil, Jacques Vervoort, Denis Barron, Walter Meinl, Hansruedi Glatt, Gary Williamson, Peter J. van Bladeren and Ivonne M. C. M. Rietjens
Drug Metabolism and Disposition April 1, 2010, 38 (4) 617-625; DOI: https://doi.org/10.1124/dmd.109.031047

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Research ArticleArticle

Phase II Metabolism of Hesperetin by Individual UDP-Glucuronosyltransferases and Sulfotransferases and Rat and Human Tissue Samples

Walter Brand, Marelle G. Boersma, Hanneke Bik, Elisabeth F. Hoek-van den Hil, Jacques Vervoort, Denis Barron, Walter Meinl, Hansruedi Glatt, Gary Williamson, Peter J. van Bladeren and Ivonne M. C. M. Rietjens
Drug Metabolism and Disposition April 1, 2010, 38 (4) 617-625; DOI: https://doi.org/10.1124/dmd.109.031047
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