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Research ArticleArticle

Cross-Species Comparison of the Metabolism and Excretion of Zoniporide: Contribution of Aldehyde Oxidase to Interspecies Differences

Deepak Dalvie, Chenghong Zhang, Weichao Chen, Teresa Smolarek, R. Scott Obach and Cho-Ming Loi
Drug Metabolism and Disposition April 2010, 38 (4) 641-654; DOI: https://doi.org/10.1124/dmd.109.030783

Article Information

vol. 38 no. 4 641-654
DOI 
https://doi.org/10.1124/dmd.109.030783
PubMed 
20040581
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 13, 2009
  • Accepted December 29, 2009
  • Published online March 16, 2010.

Article Versions

Copyright & Usage 
Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Deepak Dalvie,
  2. Chenghong Zhang1,
  3. Weichao Chen2,
  4. Teresa Smolarek,
  5. R. Scott Obach and
  6. Cho-Ming Loi
  1. Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, San Diego, California (D.D., C.-M.L.); and Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, Groton, Connecticut (C.Z., W.C., T.S., R.S.O.)
  1. Address correspondence to:
    Dr. Deepak Dalvie, 10724 Science Center Dr., San Diego, CA 92121. E-mail: deepak.dalvie{at}pfizer.com

  • ↵1 Current affiliation: Genentech, San Francisco, California.

  • ↵2 Current affiliation: Arena Pharmaceuticals, San Diego California.

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Research ArticleArticle

Cross-Species Comparison of the Metabolism and Excretion of Zoniporide: Contribution of Aldehyde Oxidase to Interspecies Differences

Deepak Dalvie, Chenghong Zhang, Weichao Chen, Teresa Smolarek, R. Scott Obach and Cho-Ming Loi
Drug Metabolism and Disposition April 1, 2010, 38 (4) 641-654; DOI: https://doi.org/10.1124/dmd.109.030783
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