Index by author
May 01, 2010; Volume 38,Issue 5
A
Ahn, Taeho
- You have accessEngineering Bacterial Cytochrome P450 (P450) BM3 into a Prototype with Human P450 Enzyme Activity Using Indigo FormationSun-Ha Park, Dong-Hyun Kim, Dooil Kim, Dae-Hwan Kim, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn, Donghak Kim and Chul-Ho YunDrug Metabolism and Disposition May 2010, 38 (5) 732-739; DOI: https://doi.org/10.1124/dmd.109.030759
Anger, Gregory
- You have accessBreast Cancer Resistance Protein (BCRP)-Mediated Glyburide Transport: Effect of the C421A/Q141K BCRP Single-Nucleotide PolymorphismErika K. Pollex, Gregory Anger, Janine Hutson, Gideon Koren and Micheline Piquette-MillerDrug Metabolism and Disposition May 2010, 38 (5) 740-744; DOI: https://doi.org/10.1124/dmd.109.030791
B
Beaton La Placa, Deirdre
- You have accessA Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent GlucuronidationHongliang Cai, Nghia Nguyen, Vincent Peterkin, Young-Sun Yang, Kathy Hotz, Deirdre Beaton La Placa, Shujuan Chen, Robert H. Tukey and Jeffrey C. StevensDrug Metabolism and Disposition May 2010, 38 (5) 879-886; DOI: https://doi.org/10.1124/dmd.109.030130
Beaumont, C.
- You have accessUse of the Entero-Test, a Novel Approach for the Noninvasive Capture of Biliary Metabolites in DogsW. J. Guiney, C. Beaumont and S. R. ThomasDrug Metabolism and Disposition May 2010, 38 (5) 851-856; DOI: https://doi.org/10.1124/dmd.109.031062
Bies, Robert R.
- You have accessMild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy VolunteersDavid Hostler, Jiangquan Zhou, Michael A. Tortorici, Robert R. Bies, Jon C. Rittenberger, Philip E. Empey, Patrick M. Kochanek, Clifton W. Callaway and Samuel M. PoloyacDrug Metabolism and Disposition May 2010, 38 (5) 781-788; DOI: https://doi.org/10.1124/dmd.109.031377
Booth-Genthe, Catherine L.
- You have accessRole of Human UGT2B10 in N-Glucuronidation of Tricyclic Antidepressants, Amitriptyline, Imipramine, Clomipramine, and TrimipramineDiansong Zhou, Jian Guo, Alban J. Linnenbach, Catherine L. Booth-Genthe and Scott W. GrimmDrug Metabolism and Disposition May 2010, 38 (5) 863-870; DOI: https://doi.org/10.1124/dmd.109.030981
Bruin, Gerard J.
- You have accessPharmacokinetics, Metabolism, and Disposition of Deferasirox in β-Thalassemic Patients with Transfusion-Dependent Iron Overload Who Are at Pharmacokinetic Steady StateFelix Waldmeier, Gerard J. Bruin, Ulrike Glaenzel, Katharine Hazell, Romain Sechaud, Steve Warrington and John B. PorterDrug Metabolism and Disposition May 2010, 38 (5) 808-816; DOI: https://doi.org/10.1124/dmd.109.030833
C
Cai, Hongliang
- You have accessA Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent GlucuronidationHongliang Cai, Nghia Nguyen, Vincent Peterkin, Young-Sun Yang, Kathy Hotz, Deirdre Beaton La Placa, Shujuan Chen, Robert H. Tukey and Jeffrey C. StevensDrug Metabolism and Disposition May 2010, 38 (5) 879-886; DOI: https://doi.org/10.1124/dmd.109.030130
Callaway, Clifton W.
- You have accessMild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy VolunteersDavid Hostler, Jiangquan Zhou, Michael A. Tortorici, Robert R. Bies, Jon C. Rittenberger, Philip E. Empey, Patrick M. Kochanek, Clifton W. Callaway and Samuel M. PoloyacDrug Metabolism and Disposition May 2010, 38 (5) 781-788; DOI: https://doi.org/10.1124/dmd.109.031377
Caritis, Steve N.
- You have accessMetabolism of 17α-Hydroxyprogesterone Caproate, an Agent for Preventing Preterm Birth, by Fetal HepatocytesShringi Sharma, Ewa C. S. Ellis, Kenneth Dorko, Shimin Zhang, Donald R. Mattison, Steve N. Caritis, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition May 2010, 38 (5) 723-727; DOI: https://doi.org/10.1124/dmd.109.029918
Carr, Darcy
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
Chandrasekaran, Appavu
- You have accessIn Vitro Metabolism and Identification of Human Enzymes Involved in the Metabolism of MethylnaltrexoneZeen Tong, Appavu Chandrasekaran, Hongshan Li, Yakov Rotshteyn, John C. L. Erve, William DeMaio, Rasmy Talaat, Theresa Hultin and JoAnn ScatinaDrug Metabolism and Disposition May 2010, 38 (5) 801-807; DOI: https://doi.org/10.1124/dmd.110.032169
Chen, Shujuan
- You have accessA Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent GlucuronidationHongliang Cai, Nghia Nguyen, Vincent Peterkin, Young-Sun Yang, Kathy Hotz, Deirdre Beaton La Placa, Shujuan Chen, Robert H. Tukey and Jeffrey C. StevensDrug Metabolism and Disposition May 2010, 38 (5) 879-886; DOI: https://doi.org/10.1124/dmd.109.030130
Clark, Shannon M.
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
Collins, Claire
- You have accessExcretion and Metabolism of Lersivirine (5-{[3,5-Diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a Next-Generation Non-Nucleoside Reverse Transcriptase Inhibitor, after Administration of [14C]Lersivirine to Healthy VolunteersManoli Vourvahis, Michelle Gleave, Angus N. R. Nedderman, Ruth Hyland, Iain Gardner, Martin Howard, Sarah Kempshall, Claire Collins and Robert LaBadieDrug Metabolism and Disposition May 2010, 38 (5) 789-800; DOI: https://doi.org/10.1124/dmd.109.031252
D
DeMaio, William
- You have accessIn Vitro Metabolism and Identification of Human Enzymes Involved in the Metabolism of MethylnaltrexoneZeen Tong, Appavu Chandrasekaran, Hongshan Li, Yakov Rotshteyn, John C. L. Erve, William DeMaio, Rasmy Talaat, Theresa Hultin and JoAnn ScatinaDrug Metabolism and Disposition May 2010, 38 (5) 801-807; DOI: https://doi.org/10.1124/dmd.110.032169
Dickman, Kathleen G.
- You have accessCytochrome P450 1A2 Detoxicates Aristolochic Acid in the MouseThomas A. Rosenquist, Heidi J. Einolf, Kathleen G. Dickman, Lai Wang, Amanda Smith and Arthur P. GrollmanDrug Metabolism and Disposition May 2010, 38 (5) 761-768; DOI: https://doi.org/10.1124/dmd.110.032201
Dorko, Kenneth
- You have accessMetabolism of 17α-Hydroxyprogesterone Caproate, an Agent for Preventing Preterm Birth, by Fetal HepatocytesShringi Sharma, Ewa C. S. Ellis, Kenneth Dorko, Shimin Zhang, Donald R. Mattison, Steve N. Caritis, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition May 2010, 38 (5) 723-727; DOI: https://doi.org/10.1124/dmd.109.029918
E
Easterling, Thomas R.
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
Einolf, Heidi J.
- You have accessCytochrome P450 1A2 Detoxicates Aristolochic Acid in the MouseThomas A. Rosenquist, Heidi J. Einolf, Kathleen G. Dickman, Lai Wang, Amanda Smith and Arthur P. GrollmanDrug Metabolism and Disposition May 2010, 38 (5) 761-768; DOI: https://doi.org/10.1124/dmd.110.032201
Ellis, Ewa C. S.
- You have accessMetabolism of 17α-Hydroxyprogesterone Caproate, an Agent for Preventing Preterm Birth, by Fetal HepatocytesShringi Sharma, Ewa C. S. Ellis, Kenneth Dorko, Shimin Zhang, Donald R. Mattison, Steve N. Caritis, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition May 2010, 38 (5) 723-727; DOI: https://doi.org/10.1124/dmd.109.029918
Empey, Philip E.
- You have accessMild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy VolunteersDavid Hostler, Jiangquan Zhou, Michael A. Tortorici, Robert R. Bies, Jon C. Rittenberger, Philip E. Empey, Patrick M. Kochanek, Clifton W. Callaway and Samuel M. PoloyacDrug Metabolism and Disposition May 2010, 38 (5) 781-788; DOI: https://doi.org/10.1124/dmd.109.031377
Erve, John C. L.
- You have accessIn Vitro Metabolism and Identification of Human Enzymes Involved in the Metabolism of MethylnaltrexoneZeen Tong, Appavu Chandrasekaran, Hongshan Li, Yakov Rotshteyn, John C. L. Erve, William DeMaio, Rasmy Talaat, Theresa Hultin and JoAnn ScatinaDrug Metabolism and Disposition May 2010, 38 (5) 801-807; DOI: https://doi.org/10.1124/dmd.110.032169
Evans, Allan M.
- You have accessInhibition of Morphine Metabolism by KetamineXiaoxin Qi, Allan M. Evans, Jiping Wang, John O. Miners, Richard N. Upton and Robert W. MilneDrug Metabolism and Disposition May 2010, 38 (5) 728-731; DOI: https://doi.org/10.1124/dmd.109.030957
Eyal, Sara
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
F
Fan, Peter W.
- You have accessBioactivation of a Novel 2-Methylindole-Containing Dual Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type-2 Cells/d-Prostanoid Receptor Antagonist Leads to Mechanism-Based CYP3A Inactivation: Glutathione Adduct Characterization and Prediction of In Vivo Drug-Drug InteractionSimon G. Wong, Peter W. Fan, Raju Subramanian, George R. Tonn, Kirk R. Henne, Michael G. Johnson, Michelle Tadano Lohr and Bradley K. WongDrug Metabolism and Disposition May 2010, 38 (5) 841-850; DOI: https://doi.org/10.1124/dmd.109.031344
G
Gardner, Iain
- You have accessExcretion and Metabolism of Lersivirine (5-{[3,5-Diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a Next-Generation Non-Nucleoside Reverse Transcriptase Inhibitor, after Administration of [14C]Lersivirine to Healthy VolunteersManoli Vourvahis, Michelle Gleave, Angus N. R. Nedderman, Ruth Hyland, Iain Gardner, Martin Howard, Sarah Kempshall, Claire Collins and Robert LaBadieDrug Metabolism and Disposition May 2010, 38 (5) 789-800; DOI: https://doi.org/10.1124/dmd.109.031252
Glaenzel, Ulrike
- You have accessPharmacokinetics, Metabolism, and Disposition of Deferasirox in β-Thalassemic Patients with Transfusion-Dependent Iron Overload Who Are at Pharmacokinetic Steady StateFelix Waldmeier, Gerard J. Bruin, Ulrike Glaenzel, Katharine Hazell, Romain Sechaud, Steve Warrington and John B. PorterDrug Metabolism and Disposition May 2010, 38 (5) 808-816; DOI: https://doi.org/10.1124/dmd.109.030833
Gleave, Michelle
- You have accessExcretion and Metabolism of Lersivirine (5-{[3,5-Diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a Next-Generation Non-Nucleoside Reverse Transcriptase Inhibitor, after Administration of [14C]Lersivirine to Healthy VolunteersManoli Vourvahis, Michelle Gleave, Angus N. R. Nedderman, Ruth Hyland, Iain Gardner, Martin Howard, Sarah Kempshall, Claire Collins and Robert LaBadieDrug Metabolism and Disposition May 2010, 38 (5) 789-800; DOI: https://doi.org/10.1124/dmd.109.031252
Grimm, Scott W.
- You have accessRole of Human UGT2B10 in N-Glucuronidation of Tricyclic Antidepressants, Amitriptyline, Imipramine, Clomipramine, and TrimipramineDiansong Zhou, Jian Guo, Alban J. Linnenbach, Catherine L. Booth-Genthe and Scott W. GrimmDrug Metabolism and Disposition May 2010, 38 (5) 863-870; DOI: https://doi.org/10.1124/dmd.109.030981
Grollman, Arthur P.
- You have accessCytochrome P450 1A2 Detoxicates Aristolochic Acid in the MouseThomas A. Rosenquist, Heidi J. Einolf, Kathleen G. Dickman, Lai Wang, Amanda Smith and Arthur P. GrollmanDrug Metabolism and Disposition May 2010, 38 (5) 761-768; DOI: https://doi.org/10.1124/dmd.110.032201
Guiney, W. J.
- You have accessUse of the Entero-Test, a Novel Approach for the Noninvasive Capture of Biliary Metabolites in DogsW. J. Guiney, C. Beaumont and S. R. ThomasDrug Metabolism and Disposition May 2010, 38 (5) 851-856; DOI: https://doi.org/10.1124/dmd.109.031062
Guo, Grace L.
- You have accessMetabolism-Mediated Drug Interactions Associated with Ritonavir-Boosted Tipranavir in MiceFeng Li, Laiyou Wang, Grace L. Guo and Xiaochao MaDrug Metabolism and Disposition May 2010, 38 (5) 871-878; DOI: https://doi.org/10.1124/dmd.109.030817
Guo, Jian
- You have accessRole of Human UGT2B10 in N-Glucuronidation of Tricyclic Antidepressants, Amitriptyline, Imipramine, Clomipramine, and TrimipramineDiansong Zhou, Jian Guo, Alban J. Linnenbach, Catherine L. Booth-Genthe and Scott W. GrimmDrug Metabolism and Disposition May 2010, 38 (5) 863-870; DOI: https://doi.org/10.1124/dmd.109.030981
H
Hankins, Gary D. V.
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
Hazell, Katharine
- You have accessPharmacokinetics, Metabolism, and Disposition of Deferasirox in β-Thalassemic Patients with Transfusion-Dependent Iron Overload Who Are at Pharmacokinetic Steady StateFelix Waldmeier, Gerard J. Bruin, Ulrike Glaenzel, Katharine Hazell, Romain Sechaud, Steve Warrington and John B. PorterDrug Metabolism and Disposition May 2010, 38 (5) 808-816; DOI: https://doi.org/10.1124/dmd.109.030833
Hebert, Mary F.
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
Hecht, Stephen S.
- You have accessFormation and Distribution of NNK Metabolites in an Isolated Perfused Rat LungLaura A. Maertens, Pramod Upadhyaya, Stephen S. Hecht and Cheryl L. ZimmermanDrug Metabolism and Disposition May 2010, 38 (5) 752-760; DOI: https://doi.org/10.1124/dmd.109.031492
Henne, Kirk R.
- You have accessBioactivation of a Novel 2-Methylindole-Containing Dual Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type-2 Cells/d-Prostanoid Receptor Antagonist Leads to Mechanism-Based CYP3A Inactivation: Glutathione Adduct Characterization and Prediction of In Vivo Drug-Drug InteractionSimon G. Wong, Peter W. Fan, Raju Subramanian, George R. Tonn, Kirk R. Henne, Michael G. Johnson, Michelle Tadano Lohr and Bradley K. WongDrug Metabolism and Disposition May 2010, 38 (5) 841-850; DOI: https://doi.org/10.1124/dmd.109.031344
Hostler, David
- You have accessMild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy VolunteersDavid Hostler, Jiangquan Zhou, Michael A. Tortorici, Robert R. Bies, Jon C. Rittenberger, Philip E. Empey, Patrick M. Kochanek, Clifton W. Callaway and Samuel M. PoloyacDrug Metabolism and Disposition May 2010, 38 (5) 781-788; DOI: https://doi.org/10.1124/dmd.109.031377
Hotz, Kathy
- You have accessA Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent GlucuronidationHongliang Cai, Nghia Nguyen, Vincent Peterkin, Young-Sun Yang, Kathy Hotz, Deirdre Beaton La Placa, Shujuan Chen, Robert H. Tukey and Jeffrey C. StevensDrug Metabolism and Disposition May 2010, 38 (5) 879-886; DOI: https://doi.org/10.1124/dmd.109.030130
Howard, Martin
- You have accessExcretion and Metabolism of Lersivirine (5-{[3,5-Diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a Next-Generation Non-Nucleoside Reverse Transcriptase Inhibitor, after Administration of [14C]Lersivirine to Healthy VolunteersManoli Vourvahis, Michelle Gleave, Angus N. R. Nedderman, Ruth Hyland, Iain Gardner, Martin Howard, Sarah Kempshall, Claire Collins and Robert LaBadieDrug Metabolism and Disposition May 2010, 38 (5) 789-800; DOI: https://doi.org/10.1124/dmd.109.031252
Hu, Zhe-Yi
- You have accessSex-Dependent Differences in Cytochrome P450 3A Activity as Assessed by Midazolam Disposition in Humans: A Meta-AnalysisZhe-Yi Hu and Yuan-Sheng ZhaoDrug Metabolism and Disposition May 2010, 38 (5) 817-823; DOI: https://doi.org/10.1124/dmd.109.031328
Hultin, Theresa
- You have accessIn Vitro Metabolism and Identification of Human Enzymes Involved in the Metabolism of MethylnaltrexoneZeen Tong, Appavu Chandrasekaran, Hongshan Li, Yakov Rotshteyn, John C. L. Erve, William DeMaio, Rasmy Talaat, Theresa Hultin and JoAnn ScatinaDrug Metabolism and Disposition May 2010, 38 (5) 801-807; DOI: https://doi.org/10.1124/dmd.110.032169
Hutson, Janine
- You have accessBreast Cancer Resistance Protein (BCRP)-Mediated Glyburide Transport: Effect of the C421A/Q141K BCRP Single-Nucleotide PolymorphismErika K. Pollex, Gregory Anger, Janine Hutson, Gideon Koren and Micheline Piquette-MillerDrug Metabolism and Disposition May 2010, 38 (5) 740-744; DOI: https://doi.org/10.1124/dmd.109.030791
Hyland, Ruth
- You have accessExcretion and Metabolism of Lersivirine (5-{[3,5-Diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a Next-Generation Non-Nucleoside Reverse Transcriptase Inhibitor, after Administration of [14C]Lersivirine to Healthy VolunteersManoli Vourvahis, Michelle Gleave, Angus N. R. Nedderman, Ruth Hyland, Iain Gardner, Martin Howard, Sarah Kempshall, Claire Collins and Robert LaBadieDrug Metabolism and Disposition May 2010, 38 (5) 789-800; DOI: https://doi.org/10.1124/dmd.109.031252
I
Ismail, Rusli
- You have accessFunctional Characterization of Cytochrome P450 2A6 Allelic Variants CYP2A6*15, CYP2A6*16, CYP2A6*21, and CYP2A6*22Kai Hung Tiong, Beow Chin Yiap, Eng Lai Tan, Rusli Ismail and Chin Eng OngDrug Metabolism and Disposition May 2010, 38 (5) 745-751; DOI: https://doi.org/10.1124/dmd.109.031054
Isobe, Naohiko
- You have accessMetabolism of 2,6-Dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl Ether (Pyridalyl) in Rats after Repeated Oral Administration and a Simple Physiologically Based Pharmacokinetic Modeling in Brown and White Adipose TissuesHirohisa Nagahori, Haruyuki Matsunaga, Yoshitaka Tomigahara, Naohiko Isobe and Hideo KanekoDrug Metabolism and Disposition May 2010, 38 (5) 824-832; DOI: https://doi.org/10.1124/dmd.109.031914
J
Johnson, Michael G.
- You have accessBioactivation of a Novel 2-Methylindole-Containing Dual Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type-2 Cells/d-Prostanoid Receptor Antagonist Leads to Mechanism-Based CYP3A Inactivation: Glutathione Adduct Characterization and Prediction of In Vivo Drug-Drug InteractionSimon G. Wong, Peter W. Fan, Raju Subramanian, George R. Tonn, Kirk R. Henne, Michael G. Johnson, Michelle Tadano Lohr and Bradley K. WongDrug Metabolism and Disposition May 2010, 38 (5) 841-850; DOI: https://doi.org/10.1124/dmd.109.031344
Jung, Heung-Chae
- You have accessEngineering Bacterial Cytochrome P450 (P450) BM3 into a Prototype with Human P450 Enzyme Activity Using Indigo FormationSun-Ha Park, Dong-Hyun Kim, Dooil Kim, Dae-Hwan Kim, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn, Donghak Kim and Chul-Ho YunDrug Metabolism and Disposition May 2010, 38 (5) 732-739; DOI: https://doi.org/10.1124/dmd.109.030759
K
Kaneko, Hideo
- You have accessMetabolism of 2,6-Dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl Ether (Pyridalyl) in Rats after Repeated Oral Administration and a Simple Physiologically Based Pharmacokinetic Modeling in Brown and White Adipose TissuesHirohisa Nagahori, Haruyuki Matsunaga, Yoshitaka Tomigahara, Naohiko Isobe and Hideo KanekoDrug Metabolism and Disposition May 2010, 38 (5) 824-832; DOI: https://doi.org/10.1124/dmd.109.031914
Kelly, Edward J.
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
Kempshall, Sarah
- You have accessExcretion and Metabolism of Lersivirine (5-{[3,5-Diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a Next-Generation Non-Nucleoside Reverse Transcriptase Inhibitor, after Administration of [14C]Lersivirine to Healthy VolunteersManoli Vourvahis, Michelle Gleave, Angus N. R. Nedderman, Ruth Hyland, Iain Gardner, Martin Howard, Sarah Kempshall, Claire Collins and Robert LaBadieDrug Metabolism and Disposition May 2010, 38 (5) 789-800; DOI: https://doi.org/10.1124/dmd.109.031252
Kim, Dae-Hwan
- You have accessEngineering Bacterial Cytochrome P450 (P450) BM3 into a Prototype with Human P450 Enzyme Activity Using Indigo FormationSun-Ha Park, Dong-Hyun Kim, Dooil Kim, Dae-Hwan Kim, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn, Donghak Kim and Chul-Ho YunDrug Metabolism and Disposition May 2010, 38 (5) 732-739; DOI: https://doi.org/10.1124/dmd.109.030759
Kim, Dong-Hyun
- You have accessEngineering Bacterial Cytochrome P450 (P450) BM3 into a Prototype with Human P450 Enzyme Activity Using Indigo FormationSun-Ha Park, Dong-Hyun Kim, Dooil Kim, Dae-Hwan Kim, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn, Donghak Kim and Chul-Ho YunDrug Metabolism and Disposition May 2010, 38 (5) 732-739; DOI: https://doi.org/10.1124/dmd.109.030759
Kim, Donghak
- You have accessEngineering Bacterial Cytochrome P450 (P450) BM3 into a Prototype with Human P450 Enzyme Activity Using Indigo FormationSun-Ha Park, Dong-Hyun Kim, Dooil Kim, Dae-Hwan Kim, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn, Donghak Kim and Chul-Ho YunDrug Metabolism and Disposition May 2010, 38 (5) 732-739; DOI: https://doi.org/10.1124/dmd.109.030759
Kim, Dooil
- You have accessEngineering Bacterial Cytochrome P450 (P450) BM3 into a Prototype with Human P450 Enzyme Activity Using Indigo FormationSun-Ha Park, Dong-Hyun Kim, Dooil Kim, Dae-Hwan Kim, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn, Donghak Kim and Chul-Ho YunDrug Metabolism and Disposition May 2010, 38 (5) 732-739; DOI: https://doi.org/10.1124/dmd.109.030759
Kochanek, Patrick M.
- You have accessMild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy VolunteersDavid Hostler, Jiangquan Zhou, Michael A. Tortorici, Robert R. Bies, Jon C. Rittenberger, Philip E. Empey, Patrick M. Kochanek, Clifton W. Callaway and Samuel M. PoloyacDrug Metabolism and Disposition May 2010, 38 (5) 781-788; DOI: https://doi.org/10.1124/dmd.109.031377
Koren, Gideon
- You have accessBreast Cancer Resistance Protein (BCRP)-Mediated Glyburide Transport: Effect of the C421A/Q141K BCRP Single-Nucleotide PolymorphismErika K. Pollex, Gregory Anger, Janine Hutson, Gideon Koren and Micheline Piquette-MillerDrug Metabolism and Disposition May 2010, 38 (5) 740-744; DOI: https://doi.org/10.1124/dmd.109.030791
L
LaBadie, Robert
- You have accessExcretion and Metabolism of Lersivirine (5-{[3,5-Diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a Next-Generation Non-Nucleoside Reverse Transcriptase Inhibitor, after Administration of [14C]Lersivirine to Healthy VolunteersManoli Vourvahis, Michelle Gleave, Angus N. R. Nedderman, Ruth Hyland, Iain Gardner, Martin Howard, Sarah Kempshall, Claire Collins and Robert LaBadieDrug Metabolism and Disposition May 2010, 38 (5) 789-800; DOI: https://doi.org/10.1124/dmd.109.031252
Li, Feng
- You have accessMetabolism-Mediated Drug Interactions Associated with Ritonavir-Boosted Tipranavir in MiceFeng Li, Laiyou Wang, Grace L. Guo and Xiaochao MaDrug Metabolism and Disposition May 2010, 38 (5) 871-878; DOI: https://doi.org/10.1124/dmd.109.030817
Li, Hongshan
- You have accessIn Vitro Metabolism and Identification of Human Enzymes Involved in the Metabolism of MethylnaltrexoneZeen Tong, Appavu Chandrasekaran, Hongshan Li, Yakov Rotshteyn, John C. L. Erve, William DeMaio, Rasmy Talaat, Theresa Hultin and JoAnn ScatinaDrug Metabolism and Disposition May 2010, 38 (5) 801-807; DOI: https://doi.org/10.1124/dmd.110.032169
Linnenbach, Alban J.
- You have accessRole of Human UGT2B10 in N-Glucuronidation of Tricyclic Antidepressants, Amitriptyline, Imipramine, Clomipramine, and TrimipramineDiansong Zhou, Jian Guo, Alban J. Linnenbach, Catherine L. Booth-Genthe and Scott W. GrimmDrug Metabolism and Disposition May 2010, 38 (5) 863-870; DOI: https://doi.org/10.1124/dmd.109.030981
M
Ma, Xiaochao
- You have accessMetabolism-Mediated Drug Interactions Associated with Ritonavir-Boosted Tipranavir in MiceFeng Li, Laiyou Wang, Grace L. Guo and Xiaochao MaDrug Metabolism and Disposition May 2010, 38 (5) 871-878; DOI: https://doi.org/10.1124/dmd.109.030817
Maertens, Laura A.
- You have accessFormation and Distribution of NNK Metabolites in an Isolated Perfused Rat LungLaura A. Maertens, Pramod Upadhyaya, Stephen S. Hecht and Cheryl L. ZimmermanDrug Metabolism and Disposition May 2010, 38 (5) 752-760; DOI: https://doi.org/10.1124/dmd.109.031492
Matsunaga, Haruyuki
- You have accessMetabolism of 2,6-Dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl Ether (Pyridalyl) in Rats after Repeated Oral Administration and a Simple Physiologically Based Pharmacokinetic Modeling in Brown and White Adipose TissuesHirohisa Nagahori, Haruyuki Matsunaga, Yoshitaka Tomigahara, Naohiko Isobe and Hideo KanekoDrug Metabolism and Disposition May 2010, 38 (5) 824-832; DOI: https://doi.org/10.1124/dmd.109.031914
Mattison, Donald R.
- You have accessMetabolism of 17α-Hydroxyprogesterone Caproate, an Agent for Preventing Preterm Birth, by Fetal HepatocytesShringi Sharma, Ewa C. S. Ellis, Kenneth Dorko, Shimin Zhang, Donald R. Mattison, Steve N. Caritis, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition May 2010, 38 (5) 723-727; DOI: https://doi.org/10.1124/dmd.109.029918
Milne, Robert W.
- You have accessInhibition of Morphine Metabolism by KetamineXiaoxin Qi, Allan M. Evans, Jiping Wang, John O. Miners, Richard N. Upton and Robert W. MilneDrug Metabolism and Disposition May 2010, 38 (5) 728-731; DOI: https://doi.org/10.1124/dmd.109.030957
Miners, John O.
- You have accessInhibition of Morphine Metabolism by KetamineXiaoxin Qi, Allan M. Evans, Jiping Wang, John O. Miners, Richard N. Upton and Robert W. MilneDrug Metabolism and Disposition May 2010, 38 (5) 728-731; DOI: https://doi.org/10.1124/dmd.109.030957
Miodovnik, Menachem
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
N
Nagahori, Hirohisa
- You have accessMetabolism of 2,6-Dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl Ether (Pyridalyl) in Rats after Repeated Oral Administration and a Simple Physiologically Based Pharmacokinetic Modeling in Brown and White Adipose TissuesHirohisa Nagahori, Haruyuki Matsunaga, Yoshitaka Tomigahara, Naohiko Isobe and Hideo KanekoDrug Metabolism and Disposition May 2010, 38 (5) 824-832; DOI: https://doi.org/10.1124/dmd.109.031914
Nedderman, Angus N. R.
- You have accessExcretion and Metabolism of Lersivirine (5-{[3,5-Diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a Next-Generation Non-Nucleoside Reverse Transcriptase Inhibitor, after Administration of [14C]Lersivirine to Healthy VolunteersManoli Vourvahis, Michelle Gleave, Angus N. R. Nedderman, Ruth Hyland, Iain Gardner, Martin Howard, Sarah Kempshall, Claire Collins and Robert LaBadieDrug Metabolism and Disposition May 2010, 38 (5) 789-800; DOI: https://doi.org/10.1124/dmd.109.031252
Nguyen, Nghia
- You have accessA Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent GlucuronidationHongliang Cai, Nghia Nguyen, Vincent Peterkin, Young-Sun Yang, Kathy Hotz, Deirdre Beaton La Placa, Shujuan Chen, Robert H. Tukey and Jeffrey C. StevensDrug Metabolism and Disposition May 2010, 38 (5) 879-886; DOI: https://doi.org/10.1124/dmd.109.030130
O
Ong, Chin Eng
- You have accessFunctional Characterization of Cytochrome P450 2A6 Allelic Variants CYP2A6*15, CYP2A6*16, CYP2A6*21, and CYP2A6*22Kai Hung Tiong, Beow Chin Yiap, Eng Lai Tan, Rusli Ismail and Chin Eng OngDrug Metabolism and Disposition May 2010, 38 (5) 745-751; DOI: https://doi.org/10.1124/dmd.109.031054
P
Pan, Jae-Gu
- You have accessEngineering Bacterial Cytochrome P450 (P450) BM3 into a Prototype with Human P450 Enzyme Activity Using Indigo FormationSun-Ha Park, Dong-Hyun Kim, Dooil Kim, Dae-Hwan Kim, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn, Donghak Kim and Chul-Ho YunDrug Metabolism and Disposition May 2010, 38 (5) 732-739; DOI: https://doi.org/10.1124/dmd.109.030759
Pang, K. Sandy
- You have accessInterplay of Phase II Enzymes and Transporters in Futile Cycling: Influence of Multidrug Resistance-Associated Protein 2-Mediated Excretion of Estradiol 17β-d-Glucuronide and Its 3-Sulfate Metabolite on Net Sulfation in Perfused TR− and Wistar Rat Liver PreparationsHuadong Sun, Ying-Ying Zeng and K. Sandy PangDrug Metabolism and Disposition May 2010, 38 (5) 769-780; DOI: https://doi.org/10.1124/dmd.109.029959
Park, Sun-Ha
- You have accessEngineering Bacterial Cytochrome P450 (P450) BM3 into a Prototype with Human P450 Enzyme Activity Using Indigo FormationSun-Ha Park, Dong-Hyun Kim, Dooil Kim, Dae-Hwan Kim, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn, Donghak Kim and Chul-Ho YunDrug Metabolism and Disposition May 2010, 38 (5) 732-739; DOI: https://doi.org/10.1124/dmd.109.030759
Peterkin, Vincent
- You have accessA Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent GlucuronidationHongliang Cai, Nghia Nguyen, Vincent Peterkin, Young-Sun Yang, Kathy Hotz, Deirdre Beaton La Placa, Shujuan Chen, Robert H. Tukey and Jeffrey C. StevensDrug Metabolism and Disposition May 2010, 38 (5) 879-886; DOI: https://doi.org/10.1124/dmd.109.030130
Piquette-Miller, Micheline
- You have accessBreast Cancer Resistance Protein (BCRP)-Mediated Glyburide Transport: Effect of the C421A/Q141K BCRP Single-Nucleotide PolymorphismErika K. Pollex, Gregory Anger, Janine Hutson, Gideon Koren and Micheline Piquette-MillerDrug Metabolism and Disposition May 2010, 38 (5) 740-744; DOI: https://doi.org/10.1124/dmd.109.030791
Pollex, Erika K.
- You have accessBreast Cancer Resistance Protein (BCRP)-Mediated Glyburide Transport: Effect of the C421A/Q141K BCRP Single-Nucleotide PolymorphismErika K. Pollex, Gregory Anger, Janine Hutson, Gideon Koren and Micheline Piquette-MillerDrug Metabolism and Disposition May 2010, 38 (5) 740-744; DOI: https://doi.org/10.1124/dmd.109.030791
Poloyac, Samuel M.
- You have accessMild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy VolunteersDavid Hostler, Jiangquan Zhou, Michael A. Tortorici, Robert R. Bies, Jon C. Rittenberger, Philip E. Empey, Patrick M. Kochanek, Clifton W. Callaway and Samuel M. PoloyacDrug Metabolism and Disposition May 2010, 38 (5) 781-788; DOI: https://doi.org/10.1124/dmd.109.031377
Porter, John B.
- You have accessPharmacokinetics, Metabolism, and Disposition of Deferasirox in β-Thalassemic Patients with Transfusion-Dependent Iron Overload Who Are at Pharmacokinetic Steady StateFelix Waldmeier, Gerard J. Bruin, Ulrike Glaenzel, Katharine Hazell, Romain Sechaud, Steve Warrington and John B. PorterDrug Metabolism and Disposition May 2010, 38 (5) 808-816; DOI: https://doi.org/10.1124/dmd.109.030833
Q
Qi, Xiaoxin
- You have accessInhibition of Morphine Metabolism by KetamineXiaoxin Qi, Allan M. Evans, Jiping Wang, John O. Miners, Richard N. Upton and Robert W. MilneDrug Metabolism and Disposition May 2010, 38 (5) 728-731; DOI: https://doi.org/10.1124/dmd.109.030957
R
Risler, Linda
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
Rittenberger, Jon C.
- You have accessMild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy VolunteersDavid Hostler, Jiangquan Zhou, Michael A. Tortorici, Robert R. Bies, Jon C. Rittenberger, Philip E. Empey, Patrick M. Kochanek, Clifton W. Callaway and Samuel M. PoloyacDrug Metabolism and Disposition May 2010, 38 (5) 781-788; DOI: https://doi.org/10.1124/dmd.109.031377
Rosenquist, Thomas A.
- You have accessCytochrome P450 1A2 Detoxicates Aristolochic Acid in the MouseThomas A. Rosenquist, Heidi J. Einolf, Kathleen G. Dickman, Lai Wang, Amanda Smith and Arthur P. GrollmanDrug Metabolism and Disposition May 2010, 38 (5) 761-768; DOI: https://doi.org/10.1124/dmd.110.032201
Rotshteyn, Yakov
- You have accessIn Vitro Metabolism and Identification of Human Enzymes Involved in the Metabolism of MethylnaltrexoneZeen Tong, Appavu Chandrasekaran, Hongshan Li, Yakov Rotshteyn, John C. L. Erve, William DeMaio, Rasmy Talaat, Theresa Hultin and JoAnn ScatinaDrug Metabolism and Disposition May 2010, 38 (5) 801-807; DOI: https://doi.org/10.1124/dmd.110.032169
S
Scatina, JoAnn
- You have accessIn Vitro Metabolism and Identification of Human Enzymes Involved in the Metabolism of MethylnaltrexoneZeen Tong, Appavu Chandrasekaran, Hongshan Li, Yakov Rotshteyn, John C. L. Erve, William DeMaio, Rasmy Talaat, Theresa Hultin and JoAnn ScatinaDrug Metabolism and Disposition May 2010, 38 (5) 801-807; DOI: https://doi.org/10.1124/dmd.110.032169
Sechaud, Romain
- You have accessPharmacokinetics, Metabolism, and Disposition of Deferasirox in β-Thalassemic Patients with Transfusion-Dependent Iron Overload Who Are at Pharmacokinetic Steady StateFelix Waldmeier, Gerard J. Bruin, Ulrike Glaenzel, Katharine Hazell, Romain Sechaud, Steve Warrington and John B. PorterDrug Metabolism and Disposition May 2010, 38 (5) 808-816; DOI: https://doi.org/10.1124/dmd.109.030833
Sharma, Shringi
- You have accessMetabolism of 17α-Hydroxyprogesterone Caproate, an Agent for Preventing Preterm Birth, by Fetal HepatocytesShringi Sharma, Ewa C. S. Ellis, Kenneth Dorko, Shimin Zhang, Donald R. Mattison, Steve N. Caritis, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition May 2010, 38 (5) 723-727; DOI: https://doi.org/10.1124/dmd.109.029918
Shen, Danny D.
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
Smith, Amanda
- You have accessCytochrome P450 1A2 Detoxicates Aristolochic Acid in the MouseThomas A. Rosenquist, Heidi J. Einolf, Kathleen G. Dickman, Lai Wang, Amanda Smith and Arthur P. GrollmanDrug Metabolism and Disposition May 2010, 38 (5) 761-768; DOI: https://doi.org/10.1124/dmd.110.032201
Squires, E. J.
- You have accessChlorzoxazone Metabolism by Porcine Cytochrome P450 Enzymes and the Effect of Cytochrome b5P. Wiercinska and E. J. SquiresDrug Metabolism and Disposition May 2010, 38 (5) 857-862; DOI: https://doi.org/10.1124/dmd.109.030528
Stevens, Jeffrey C.
- You have accessA Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent GlucuronidationHongliang Cai, Nghia Nguyen, Vincent Peterkin, Young-Sun Yang, Kathy Hotz, Deirdre Beaton La Placa, Shujuan Chen, Robert H. Tukey and Jeffrey C. StevensDrug Metabolism and Disposition May 2010, 38 (5) 879-886; DOI: https://doi.org/10.1124/dmd.109.030130
Strom, Stephen C.
- You have accessMetabolism of 17α-Hydroxyprogesterone Caproate, an Agent for Preventing Preterm Birth, by Fetal HepatocytesShringi Sharma, Ewa C. S. Ellis, Kenneth Dorko, Shimin Zhang, Donald R. Mattison, Steve N. Caritis, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition May 2010, 38 (5) 723-727; DOI: https://doi.org/10.1124/dmd.109.029918
Subramanian, Raju
- You have accessBioactivation of a Novel 2-Methylindole-Containing Dual Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type-2 Cells/d-Prostanoid Receptor Antagonist Leads to Mechanism-Based CYP3A Inactivation: Glutathione Adduct Characterization and Prediction of In Vivo Drug-Drug InteractionSimon G. Wong, Peter W. Fan, Raju Subramanian, George R. Tonn, Kirk R. Henne, Michael G. Johnson, Michelle Tadano Lohr and Bradley K. WongDrug Metabolism and Disposition May 2010, 38 (5) 841-850; DOI: https://doi.org/10.1124/dmd.109.031344
Sun, Huadong
- You have accessInterplay of Phase II Enzymes and Transporters in Futile Cycling: Influence of Multidrug Resistance-Associated Protein 2-Mediated Excretion of Estradiol 17β-d-Glucuronide and Its 3-Sulfate Metabolite on Net Sulfation in Perfused TR− and Wistar Rat Liver PreparationsHuadong Sun, Ying-Ying Zeng and K. Sandy PangDrug Metabolism and Disposition May 2010, 38 (5) 769-780; DOI: https://doi.org/10.1124/dmd.109.029959
T
Tadano Lohr, Michelle
- You have accessBioactivation of a Novel 2-Methylindole-Containing Dual Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type-2 Cells/d-Prostanoid Receptor Antagonist Leads to Mechanism-Based CYP3A Inactivation: Glutathione Adduct Characterization and Prediction of In Vivo Drug-Drug InteractionSimon G. Wong, Peter W. Fan, Raju Subramanian, George R. Tonn, Kirk R. Henne, Michael G. Johnson, Michelle Tadano Lohr and Bradley K. WongDrug Metabolism and Disposition May 2010, 38 (5) 841-850; DOI: https://doi.org/10.1124/dmd.109.031344
Talaat, Rasmy
- You have accessIn Vitro Metabolism and Identification of Human Enzymes Involved in the Metabolism of MethylnaltrexoneZeen Tong, Appavu Chandrasekaran, Hongshan Li, Yakov Rotshteyn, John C. L. Erve, William DeMaio, Rasmy Talaat, Theresa Hultin and JoAnn ScatinaDrug Metabolism and Disposition May 2010, 38 (5) 801-807; DOI: https://doi.org/10.1124/dmd.110.032169
Tan, Eng Lai
- You have accessFunctional Characterization of Cytochrome P450 2A6 Allelic Variants CYP2A6*15, CYP2A6*16, CYP2A6*21, and CYP2A6*22Kai Hung Tiong, Beow Chin Yiap, Eng Lai Tan, Rusli Ismail and Chin Eng OngDrug Metabolism and Disposition May 2010, 38 (5) 745-751; DOI: https://doi.org/10.1124/dmd.109.031054
Thomas, S. R.
- You have accessUse of the Entero-Test, a Novel Approach for the Noninvasive Capture of Biliary Metabolites in DogsW. J. Guiney, C. Beaumont and S. R. ThomasDrug Metabolism and Disposition May 2010, 38 (5) 851-856; DOI: https://doi.org/10.1124/dmd.109.031062
Tiong, Kai Hung
- You have accessFunctional Characterization of Cytochrome P450 2A6 Allelic Variants CYP2A6*15, CYP2A6*16, CYP2A6*21, and CYP2A6*22Kai Hung Tiong, Beow Chin Yiap, Eng Lai Tan, Rusli Ismail and Chin Eng OngDrug Metabolism and Disposition May 2010, 38 (5) 745-751; DOI: https://doi.org/10.1124/dmd.109.031054
Tomigahara, Yoshitaka
- You have accessMetabolism of 2,6-Dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl Ether (Pyridalyl) in Rats after Repeated Oral Administration and a Simple Physiologically Based Pharmacokinetic Modeling in Brown and White Adipose TissuesHirohisa Nagahori, Haruyuki Matsunaga, Yoshitaka Tomigahara, Naohiko Isobe and Hideo KanekoDrug Metabolism and Disposition May 2010, 38 (5) 824-832; DOI: https://doi.org/10.1124/dmd.109.031914
Tong, Zeen
- You have accessIn Vitro Metabolism and Identification of Human Enzymes Involved in the Metabolism of MethylnaltrexoneZeen Tong, Appavu Chandrasekaran, Hongshan Li, Yakov Rotshteyn, John C. L. Erve, William DeMaio, Rasmy Talaat, Theresa Hultin and JoAnn ScatinaDrug Metabolism and Disposition May 2010, 38 (5) 801-807; DOI: https://doi.org/10.1124/dmd.110.032169
Tonn, George R.
- You have accessBioactivation of a Novel 2-Methylindole-Containing Dual Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type-2 Cells/d-Prostanoid Receptor Antagonist Leads to Mechanism-Based CYP3A Inactivation: Glutathione Adduct Characterization and Prediction of In Vivo Drug-Drug InteractionSimon G. Wong, Peter W. Fan, Raju Subramanian, George R. Tonn, Kirk R. Henne, Michael G. Johnson, Michelle Tadano Lohr and Bradley K. WongDrug Metabolism and Disposition May 2010, 38 (5) 841-850; DOI: https://doi.org/10.1124/dmd.109.031344
Tortorici, Michael A.
- You have accessMild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy VolunteersDavid Hostler, Jiangquan Zhou, Michael A. Tortorici, Robert R. Bies, Jon C. Rittenberger, Philip E. Empey, Patrick M. Kochanek, Clifton W. Callaway and Samuel M. PoloyacDrug Metabolism and Disposition May 2010, 38 (5) 781-788; DOI: https://doi.org/10.1124/dmd.109.031377
Tukey, Robert H.
- You have accessA Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent GlucuronidationHongliang Cai, Nghia Nguyen, Vincent Peterkin, Young-Sun Yang, Kathy Hotz, Deirdre Beaton La Placa, Shujuan Chen, Robert H. Tukey and Jeffrey C. StevensDrug Metabolism and Disposition May 2010, 38 (5) 879-886; DOI: https://doi.org/10.1124/dmd.109.030130
U
Umans, Jason G.
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
Upadhyaya, Pramod
- You have accessFormation and Distribution of NNK Metabolites in an Isolated Perfused Rat LungLaura A. Maertens, Pramod Upadhyaya, Stephen S. Hecht and Cheryl L. ZimmermanDrug Metabolism and Disposition May 2010, 38 (5) 752-760; DOI: https://doi.org/10.1124/dmd.109.031492
Upton, Richard N.
- You have accessInhibition of Morphine Metabolism by KetamineXiaoxin Qi, Allan M. Evans, Jiping Wang, John O. Miners, Richard N. Upton and Robert W. MilneDrug Metabolism and Disposition May 2010, 38 (5) 728-731; DOI: https://doi.org/10.1124/dmd.109.030957
V
Venkataramanan, Raman
- You have accessMetabolism of 17α-Hydroxyprogesterone Caproate, an Agent for Preventing Preterm Birth, by Fetal HepatocytesShringi Sharma, Ewa C. S. Ellis, Kenneth Dorko, Shimin Zhang, Donald R. Mattison, Steve N. Caritis, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition May 2010, 38 (5) 723-727; DOI: https://doi.org/10.1124/dmd.109.029918
Vourvahis, Manoli
- You have accessExcretion and Metabolism of Lersivirine (5-{[3,5-Diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a Next-Generation Non-Nucleoside Reverse Transcriptase Inhibitor, after Administration of [14C]Lersivirine to Healthy VolunteersManoli Vourvahis, Michelle Gleave, Angus N. R. Nedderman, Ruth Hyland, Iain Gardner, Martin Howard, Sarah Kempshall, Claire Collins and Robert LaBadieDrug Metabolism and Disposition May 2010, 38 (5) 789-800; DOI: https://doi.org/10.1124/dmd.109.031252
W
Waldmeier, Felix
- You have accessPharmacokinetics, Metabolism, and Disposition of Deferasirox in β-Thalassemic Patients with Transfusion-Dependent Iron Overload Who Are at Pharmacokinetic Steady StateFelix Waldmeier, Gerard J. Bruin, Ulrike Glaenzel, Katharine Hazell, Romain Sechaud, Steve Warrington and John B. PorterDrug Metabolism and Disposition May 2010, 38 (5) 808-816; DOI: https://doi.org/10.1124/dmd.109.030833
Wang, Jiping
- You have accessInhibition of Morphine Metabolism by KetamineXiaoxin Qi, Allan M. Evans, Jiping Wang, John O. Miners, Richard N. Upton and Robert W. MilneDrug Metabolism and Disposition May 2010, 38 (5) 728-731; DOI: https://doi.org/10.1124/dmd.109.030957
Wang, Joanne
- You have accessPharmacokinetics of Metformin during PregnancySara Eyal, Thomas R. Easterling, Darcy Carr, Jason G. Umans, Menachem Miodovnik, Gary D. V. Hankins, Shannon M. Clark, Linda Risler, Joanne Wang, Edward J. Kelly, Danny D. Shen and Mary F. HebertDrug Metabolism and Disposition May 2010, 38 (5) 833-840; DOI: https://doi.org/10.1124/dmd.109.031245
Wang, Lai
- You have accessCytochrome P450 1A2 Detoxicates Aristolochic Acid in the MouseThomas A. Rosenquist, Heidi J. Einolf, Kathleen G. Dickman, Lai Wang, Amanda Smith and Arthur P. GrollmanDrug Metabolism and Disposition May 2010, 38 (5) 761-768; DOI: https://doi.org/10.1124/dmd.110.032201
Wang, Laiyou
- You have accessMetabolism-Mediated Drug Interactions Associated with Ritonavir-Boosted Tipranavir in MiceFeng Li, Laiyou Wang, Grace L. Guo and Xiaochao MaDrug Metabolism and Disposition May 2010, 38 (5) 871-878; DOI: https://doi.org/10.1124/dmd.109.030817
Warrington, Steve
- You have accessPharmacokinetics, Metabolism, and Disposition of Deferasirox in β-Thalassemic Patients with Transfusion-Dependent Iron Overload Who Are at Pharmacokinetic Steady StateFelix Waldmeier, Gerard J. Bruin, Ulrike Glaenzel, Katharine Hazell, Romain Sechaud, Steve Warrington and John B. PorterDrug Metabolism and Disposition May 2010, 38 (5) 808-816; DOI: https://doi.org/10.1124/dmd.109.030833
Wiercinska, P.
- You have accessChlorzoxazone Metabolism by Porcine Cytochrome P450 Enzymes and the Effect of Cytochrome b5P. Wiercinska and E. J. SquiresDrug Metabolism and Disposition May 2010, 38 (5) 857-862; DOI: https://doi.org/10.1124/dmd.109.030528
Wong, Bradley K.
- You have accessBioactivation of a Novel 2-Methylindole-Containing Dual Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type-2 Cells/d-Prostanoid Receptor Antagonist Leads to Mechanism-Based CYP3A Inactivation: Glutathione Adduct Characterization and Prediction of In Vivo Drug-Drug InteractionSimon G. Wong, Peter W. Fan, Raju Subramanian, George R. Tonn, Kirk R. Henne, Michael G. Johnson, Michelle Tadano Lohr and Bradley K. WongDrug Metabolism and Disposition May 2010, 38 (5) 841-850; DOI: https://doi.org/10.1124/dmd.109.031344
Wong, Simon G.
- You have accessBioactivation of a Novel 2-Methylindole-Containing Dual Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type-2 Cells/d-Prostanoid Receptor Antagonist Leads to Mechanism-Based CYP3A Inactivation: Glutathione Adduct Characterization and Prediction of In Vivo Drug-Drug InteractionSimon G. Wong, Peter W. Fan, Raju Subramanian, George R. Tonn, Kirk R. Henne, Michael G. Johnson, Michelle Tadano Lohr and Bradley K. WongDrug Metabolism and Disposition May 2010, 38 (5) 841-850; DOI: https://doi.org/10.1124/dmd.109.031344
Y
Yang, Young-Sun
- You have accessA Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent GlucuronidationHongliang Cai, Nghia Nguyen, Vincent Peterkin, Young-Sun Yang, Kathy Hotz, Deirdre Beaton La Placa, Shujuan Chen, Robert H. Tukey and Jeffrey C. StevensDrug Metabolism and Disposition May 2010, 38 (5) 879-886; DOI: https://doi.org/10.1124/dmd.109.030130
Yiap, Beow Chin
- You have accessFunctional Characterization of Cytochrome P450 2A6 Allelic Variants CYP2A6*15, CYP2A6*16, CYP2A6*21, and CYP2A6*22Kai Hung Tiong, Beow Chin Yiap, Eng Lai Tan, Rusli Ismail and Chin Eng OngDrug Metabolism and Disposition May 2010, 38 (5) 745-751; DOI: https://doi.org/10.1124/dmd.109.031054
Yun, Chul-Ho
- You have accessEngineering Bacterial Cytochrome P450 (P450) BM3 into a Prototype with Human P450 Enzyme Activity Using Indigo FormationSun-Ha Park, Dong-Hyun Kim, Dooil Kim, Dae-Hwan Kim, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn, Donghak Kim and Chul-Ho YunDrug Metabolism and Disposition May 2010, 38 (5) 732-739; DOI: https://doi.org/10.1124/dmd.109.030759
Z
Zeng, Ying-Ying
- You have accessInterplay of Phase II Enzymes and Transporters in Futile Cycling: Influence of Multidrug Resistance-Associated Protein 2-Mediated Excretion of Estradiol 17β-d-Glucuronide and Its 3-Sulfate Metabolite on Net Sulfation in Perfused TR− and Wistar Rat Liver PreparationsHuadong Sun, Ying-Ying Zeng and K. Sandy PangDrug Metabolism and Disposition May 2010, 38 (5) 769-780; DOI: https://doi.org/10.1124/dmd.109.029959
Zhang, Shimin
- You have accessMetabolism of 17α-Hydroxyprogesterone Caproate, an Agent for Preventing Preterm Birth, by Fetal HepatocytesShringi Sharma, Ewa C. S. Ellis, Kenneth Dorko, Shimin Zhang, Donald R. Mattison, Steve N. Caritis, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition May 2010, 38 (5) 723-727; DOI: https://doi.org/10.1124/dmd.109.029918
Zhao, Yuan-Sheng
- You have accessSex-Dependent Differences in Cytochrome P450 3A Activity as Assessed by Midazolam Disposition in Humans: A Meta-AnalysisZhe-Yi Hu and Yuan-Sheng ZhaoDrug Metabolism and Disposition May 2010, 38 (5) 817-823; DOI: https://doi.org/10.1124/dmd.109.031328
Zhou, Diansong
- You have accessRole of Human UGT2B10 in N-Glucuronidation of Tricyclic Antidepressants, Amitriptyline, Imipramine, Clomipramine, and TrimipramineDiansong Zhou, Jian Guo, Alban J. Linnenbach, Catherine L. Booth-Genthe and Scott W. GrimmDrug Metabolism and Disposition May 2010, 38 (5) 863-870; DOI: https://doi.org/10.1124/dmd.109.030981
Zhou, Jiangquan
- You have accessMild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy VolunteersDavid Hostler, Jiangquan Zhou, Michael A. Tortorici, Robert R. Bies, Jon C. Rittenberger, Philip E. Empey, Patrick M. Kochanek, Clifton W. Callaway and Samuel M. PoloyacDrug Metabolism and Disposition May 2010, 38 (5) 781-788; DOI: https://doi.org/10.1124/dmd.109.031377
Zimmerman, Cheryl L.
- You have accessFormation and Distribution of NNK Metabolites in an Isolated Perfused Rat LungLaura A. Maertens, Pramod Upadhyaya, Stephen S. Hecht and Cheryl L. ZimmermanDrug Metabolism and Disposition May 2010, 38 (5) 752-760; DOI: https://doi.org/10.1124/dmd.109.031492
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