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Rapid CommunicationShort Communication

Potential Application of d-Optimal Designs in the Efficient Investigation of Cytochrome P450 Inhibition Kinetic Models

Kuresh A. Youdim, Anthony C. Atkinson, Maciej Patan, Barbara Bogacka and Patrick J. Johnson
Drug Metabolism and Disposition July 2010, 38 (7) 1019-1023; DOI: https://doi.org/10.1124/dmd.110.033142
Kuresh A. Youdim
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Anthony C. Atkinson
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Maciej Patan
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Barbara Bogacka
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Patrick J. Johnson
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Article Information

vol. 38 no. 7 1019-1023
DOI 
https://doi.org/10.1124/dmd.110.033142
PubMed 
20400659

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 11, 2010
  • Accepted April 16, 2010
  • Published online June 15, 2010.

Article Versions

  • Earlier version (April 16, 2010 - 11:06).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Kuresh A. Youdim,
  2. Anthony C. Atkinson,
  3. Maciej Patan,
  4. Barbara Bogacka and
  5. Patrick J. Johnson
  1. Pfizer Global Research and Development, Sandwich, Kent, United Kingdom (K.A.Y., P.J.J.); Department of Statistics, London School of Economics and Political Science, London, United Kingdom (A.C.A.); Institute of Control and Computation Engineering, University of Zielona Góra, Zielona Góra, Poland (M.P.); and School of Mathematical Sciences, Queen Mary, University of London, London, United Kingdom (B.B.)
  1. Address correspondence to:
    Kuresh Youdim, Pfizer Global Research and Development, Ramsgate Rd., Sandwich, Kent CT13 9NJ, UK. E-mail: kuresh.youdim{at}pfizer.com
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Drug Metabolism and Disposition: 38 (7)
Drug Metabolism and Disposition
Vol. 38, Issue 7
1 Jul 2010
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Rapid CommunicationShort Communication

Potential Application of d-Optimal Designs in the Efficient Investigation of Cytochrome P450 Inhibition Kinetic Models

Kuresh A. Youdim, Anthony C. Atkinson, Maciej Patan, Barbara Bogacka and Patrick J. Johnson
Drug Metabolism and Disposition July 1, 2010, 38 (7) 1019-1023; DOI: https://doi.org/10.1124/dmd.110.033142

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Rapid CommunicationShort Communication

Potential Application of d-Optimal Designs in the Efficient Investigation of Cytochrome P450 Inhibition Kinetic Models

Kuresh A. Youdim, Anthony C. Atkinson, Maciej Patan, Barbara Bogacka and Patrick J. Johnson
Drug Metabolism and Disposition July 1, 2010, 38 (7) 1019-1023; DOI: https://doi.org/10.1124/dmd.110.033142
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