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Index by author

August 01, 2010; Volume 38,Issue 8

A

  1. Akiyama, Yutaka

    1. In Silico Classification of Major Clearance Pathways of Drugs with Their Physiochemical Parameters
      Makiko Kusama, Kouta Toshimoto, Kazuya Maeda, Yuka Hirai, Satoki Imai, Koji Chiba, Yutaka Akiyama and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2010, 38 (8) 1362-1370; DOI: https://doi.org/10.1124/dmd.110.032789

  2. Ambudkar, Suresh V.

    1. Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib
      Marius Dohse, Christian Scharenberg, Suneet Shukla, Robert W. Robey, Thorsten Volkmann, John F. Deeken, Cornelia Brendel, Suresh V. Ambudkar, Andreas Neubauer and Susan E. Bates
      Drug Metabolism and Disposition August 2010, 38 (8) 1371-1380; DOI: https://doi.org/10.1124/dmd.109.031302

  3. Argikar, Upendra A.

    1. Identification of Novel Metoclopramide Metabolites in Humans: In Vitro and In Vivo Studies
      Upendra A. Argikar, Javier Gomez, Din Ung, Henry P. Parkman and Swati Nagar
      Drug Metabolism and Disposition August 2010, 38 (8) 1295-1307; DOI: https://doi.org/10.1124/dmd.110.033357

B

  1. Baba, Kimiye

    1. Furanocoumarin Derivatives in Kampo Extract Medicines Inhibit Cytochrome P450 3A4 and P-Glycoprotein
      Kazunori Iwanaga, Manami Hayashi, Yukimi Hamahata, Makoto Miyazaki, Makio Shibano, Masahiko Taniguchi, Kimiye Baba and Masawo Kakemi
      Drug Metabolism and Disposition August 2010, 38 (8) 1286-1294; DOI: https://doi.org/10.1124/dmd.110.032847

  2. Bates, Susan E.

    1. Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib
      Marius Dohse, Christian Scharenberg, Suneet Shukla, Robert W. Robey, Thorsten Volkmann, John F. Deeken, Cornelia Brendel, Suresh V. Ambudkar, Andreas Neubauer and Susan E. Bates
      Drug Metabolism and Disposition August 2010, 38 (8) 1371-1380; DOI: https://doi.org/10.1124/dmd.109.031302

  3. Bies, Robert

    1. Methadone: A Substrate and Mechanism-Based Inhibitor of CYP19 (Aromatase)
      Wenjie Jessie Lu, Robert Bies, Landry K. Kamden, Zeruesenay Desta and David A. Flockhart
      Drug Metabolism and Disposition August 2010, 38 (8) 1308-1313; DOI: https://doi.org/10.1124/dmd.110.032474

  4. Boddy, Alan V.

    1. Relevance of Nonsynonymous CYP2C8 Polymorphisms to 13-cis Retinoic Acid and Paclitaxel Hydroxylation
      Sophie E. Rowbotham, Alan V. Boddy, Chris P. F. Redfern, Gareth J. Veal and Ann K. Daly
      Drug Metabolism and Disposition August 2010, 38 (8) 1261-1266; DOI: https://doi.org/10.1124/dmd.109.030866

  5. Boer, Jason

    1. Species-Specific Metabolism of SGX523 by Aldehyde Oxidase and the Toxicological Implications
      Sharon Diamond, Jason Boer, Thomas P. Maduskuie, Nikoo Falahatpisheh, Yu Li and Swamy Yeleswaram
      Drug Metabolism and Disposition August 2010, 38 (8) 1277-1285; DOI: https://doi.org/10.1124/dmd.110.032375

  6. Brendel, Cornelia

    1. Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib
      Marius Dohse, Christian Scharenberg, Suneet Shukla, Robert W. Robey, Thorsten Volkmann, John F. Deeken, Cornelia Brendel, Suresh V. Ambudkar, Andreas Neubauer and Susan E. Bates
      Drug Metabolism and Disposition August 2010, 38 (8) 1371-1380; DOI: https://doi.org/10.1124/dmd.109.031302

C

  1. Chen, Xiaoyan

    1. Metabolism of Flumatinib, a Novel Antineoplastic Tyrosine Kinase Inhibitor, in Chronic Myelogenous Leukemia Patients
      Aishen Gong, Xiaoyan Chen, Pan Deng and Dafang Zhong
      Drug Metabolism and Disposition August 2010, 38 (8) 1328-1340; DOI: https://doi.org/10.1124/dmd.110.032326

  2. Cheng, Ziqiang

    1. Central Nervous System Penetration for Small Molecule Therapeutic Agents Does Not Increase in Multiple Sclerosis- and Alzheimer's Disease-Related Animal Models Despite Reported Blood-Brain Barrier Disruption
      Ziqiang Cheng, Jinqiang Zhang, Houfu Liu, Yi Li, Yonggang Zhao and Eric Yang
      Drug Metabolism and Disposition August 2010, 38 (8) 1355-1361; DOI: https://doi.org/10.1124/dmd.110.033324

  3. Chiba, Koji

    1. In Silico Classification of Major Clearance Pathways of Drugs with Their Physiochemical Parameters
      Makiko Kusama, Kouta Toshimoto, Kazuya Maeda, Yuka Hirai, Satoki Imai, Koji Chiba, Yutaka Akiyama and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2010, 38 (8) 1362-1370; DOI: https://doi.org/10.1124/dmd.110.032789

D

  1. Daly, Ann K.

    1. Relevance of Nonsynonymous CYP2C8 Polymorphisms to 13-cis Retinoic Acid and Paclitaxel Hydroxylation
      Sophie E. Rowbotham, Alan V. Boddy, Chris P. F. Redfern, Gareth J. Veal and Ann K. Daly
      Drug Metabolism and Disposition August 2010, 38 (8) 1261-1266; DOI: https://doi.org/10.1124/dmd.109.030866

  2. Deeken, John F.

    1. Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib
      Marius Dohse, Christian Scharenberg, Suneet Shukla, Robert W. Robey, Thorsten Volkmann, John F. Deeken, Cornelia Brendel, Suresh V. Ambudkar, Andreas Neubauer and Susan E. Bates
      Drug Metabolism and Disposition August 2010, 38 (8) 1371-1380; DOI: https://doi.org/10.1124/dmd.109.031302

  3. Deng, Pan

    1. Metabolism of Flumatinib, a Novel Antineoplastic Tyrosine Kinase Inhibitor, in Chronic Myelogenous Leukemia Patients
      Aishen Gong, Xiaoyan Chen, Pan Deng and Dafang Zhong
      Drug Metabolism and Disposition August 2010, 38 (8) 1328-1340; DOI: https://doi.org/10.1124/dmd.110.032326

  4. Desta, Zeruesenay

    1. Methadone: A Substrate and Mechanism-Based Inhibitor of CYP19 (Aromatase)
      Wenjie Jessie Lu, Robert Bies, Landry K. Kamden, Zeruesenay Desta and David A. Flockhart
      Drug Metabolism and Disposition August 2010, 38 (8) 1308-1313; DOI: https://doi.org/10.1124/dmd.110.032474

  5. Diamond, Sharon

    1. Species-Specific Metabolism of SGX523 by Aldehyde Oxidase and the Toxicological Implications
      Sharon Diamond, Jason Boer, Thomas P. Maduskuie, Nikoo Falahatpisheh, Yu Li and Swamy Yeleswaram
      Drug Metabolism and Disposition August 2010, 38 (8) 1277-1285; DOI: https://doi.org/10.1124/dmd.110.032375

  6. Dohse, Marius

    1. Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib
      Marius Dohse, Christian Scharenberg, Suneet Shukla, Robert W. Robey, Thorsten Volkmann, John F. Deeken, Cornelia Brendel, Suresh V. Ambudkar, Andreas Neubauer and Susan E. Bates
      Drug Metabolism and Disposition August 2010, 38 (8) 1371-1380; DOI: https://doi.org/10.1124/dmd.109.031302

E

  1. Engel, K.

    1. In Vitro to In Vivo Comparison of the Substrate Characteristics of Sorafenib Tosylate toward P-Glycoprotein
      M. J. Gnoth, S. Sandmann, K. Engel and M. Radtke
      Drug Metabolism and Disposition August 2010, 38 (8) 1341-1346; DOI: https://doi.org/10.1124/dmd.110.032052

F

  1. Falahatpisheh, Nikoo

    1. Species-Specific Metabolism of SGX523 by Aldehyde Oxidase and the Toxicological Implications
      Sharon Diamond, Jason Boer, Thomas P. Maduskuie, Nikoo Falahatpisheh, Yu Li and Swamy Yeleswaram
      Drug Metabolism and Disposition August 2010, 38 (8) 1277-1285; DOI: https://doi.org/10.1124/dmd.110.032375

  2. Flockhart, David A.

    1. Methadone: A Substrate and Mechanism-Based Inhibitor of CYP19 (Aromatase)
      Wenjie Jessie Lu, Robert Bies, Landry K. Kamden, Zeruesenay Desta and David A. Flockhart
      Drug Metabolism and Disposition August 2010, 38 (8) 1308-1313; DOI: https://doi.org/10.1124/dmd.110.032474

G

  1. Gnoth, M. J.

    1. In Vitro to In Vivo Comparison of the Substrate Characteristics of Sorafenib Tosylate toward P-Glycoprotein
      M. J. Gnoth, S. Sandmann, K. Engel and M. Radtke
      Drug Metabolism and Disposition August 2010, 38 (8) 1341-1346; DOI: https://doi.org/10.1124/dmd.110.032052

  2. Gomez, Javier

    1. Identification of Novel Metoclopramide Metabolites in Humans: In Vitro and In Vivo Studies
      Upendra A. Argikar, Javier Gomez, Din Ung, Henry P. Parkman and Swati Nagar
      Drug Metabolism and Disposition August 2010, 38 (8) 1295-1307; DOI: https://doi.org/10.1124/dmd.110.033357

  3. Gong, Aishen

    1. Metabolism of Flumatinib, a Novel Antineoplastic Tyrosine Kinase Inhibitor, in Chronic Myelogenous Leukemia Patients
      Aishen Gong, Xiaoyan Chen, Pan Deng and Dafang Zhong
      Drug Metabolism and Disposition August 2010, 38 (8) 1328-1340; DOI: https://doi.org/10.1124/dmd.110.032326

H

  1. Hamahata, Yukimi

    1. Furanocoumarin Derivatives in Kampo Extract Medicines Inhibit Cytochrome P450 3A4 and P-Glycoprotein
      Kazunori Iwanaga, Manami Hayashi, Yukimi Hamahata, Makoto Miyazaki, Makio Shibano, Masahiko Taniguchi, Kimiye Baba and Masawo Kakemi
      Drug Metabolism and Disposition August 2010, 38 (8) 1286-1294; DOI: https://doi.org/10.1124/dmd.110.032847

  2. Hayashi, Manami

    1. Furanocoumarin Derivatives in Kampo Extract Medicines Inhibit Cytochrome P450 3A4 and P-Glycoprotein
      Kazunori Iwanaga, Manami Hayashi, Yukimi Hamahata, Makoto Miyazaki, Makio Shibano, Masahiko Taniguchi, Kimiye Baba and Masawo Kakemi
      Drug Metabolism and Disposition August 2010, 38 (8) 1286-1294; DOI: https://doi.org/10.1124/dmd.110.032847

  3. Hirai, Yuka

    1. In Silico Classification of Major Clearance Pathways of Drugs with Their Physiochemical Parameters
      Makiko Kusama, Kouta Toshimoto, Kazuya Maeda, Yuka Hirai, Satoki Imai, Koji Chiba, Yutaka Akiyama and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2010, 38 (8) 1362-1370; DOI: https://doi.org/10.1124/dmd.110.032789

I

  1. Imai, Satoki

    1. In Silico Classification of Major Clearance Pathways of Drugs with Their Physiochemical Parameters
      Makiko Kusama, Kouta Toshimoto, Kazuya Maeda, Yuka Hirai, Satoki Imai, Koji Chiba, Yutaka Akiyama and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2010, 38 (8) 1362-1370; DOI: https://doi.org/10.1124/dmd.110.032789

  2. Ito, Yoshihiko

    1. The N-Oxide Metabolite Contributes to Bladder Selectivity Resulting from Oral Propiverine: Muscarinic Receptor Binding and Pharmacokinetics
      Shizuo Yamada, Yoshihiko Ito, Yuko Taki, Masanao Seki, Masato Nanri, Fumiaki Yamashita, Kayo Morishita, Ikumi Komoto and Ken-ichiro Yoshida
      Drug Metabolism and Disposition August 2010, 38 (8) 1314-1321; DOI: https://doi.org/10.1124/dmd.110.033233

  3. Iwanaga, Kazunori

    1. Furanocoumarin Derivatives in Kampo Extract Medicines Inhibit Cytochrome P450 3A4 and P-Glycoprotein
      Kazunori Iwanaga, Manami Hayashi, Yukimi Hamahata, Makoto Miyazaki, Makio Shibano, Masahiko Taniguchi, Kimiye Baba and Masawo Kakemi
      Drug Metabolism and Disposition August 2010, 38 (8) 1286-1294; DOI: https://doi.org/10.1124/dmd.110.032847

J

  1. Jiang, Ying

    1. In Vitro-In Vivo Correlation for Intrinsic Clearance for Drugs Metabolized by Human Aldehyde Oxidase
      Michael Zientek, Ying Jiang, Kuresh Youdim and R. Scott Obach
      Drug Metabolism and Disposition August 2010, 38 (8) 1322-1327; DOI: https://doi.org/10.1124/dmd.110.033555

  2. Jørgensen, Flemming Steen

    1. Computational Prediction of Binding Affinity for CYP1A2-Ligand Complexes Using Empirical Free Energy Calculations
      Poongavanam Vasanthanathan, Lars Olsen, Flemming Steen Jørgensen, Nico P. E. Vermeulen and Chris Oostenbrink
      Drug Metabolism and Disposition August 2010, 38 (8) 1347-1354; DOI: https://doi.org/10.1124/dmd.110.032946

K

  1. Kakemi, Masawo

    1. Furanocoumarin Derivatives in Kampo Extract Medicines Inhibit Cytochrome P450 3A4 and P-Glycoprotein
      Kazunori Iwanaga, Manami Hayashi, Yukimi Hamahata, Makoto Miyazaki, Makio Shibano, Masahiko Taniguchi, Kimiye Baba and Masawo Kakemi
      Drug Metabolism and Disposition August 2010, 38 (8) 1286-1294; DOI: https://doi.org/10.1124/dmd.110.032847

  2. Kamden, Landry K.

    1. Methadone: A Substrate and Mechanism-Based Inhibitor of CYP19 (Aromatase)
      Wenjie Jessie Lu, Robert Bies, Landry K. Kamden, Zeruesenay Desta and David A. Flockhart
      Drug Metabolism and Disposition August 2010, 38 (8) 1308-1313; DOI: https://doi.org/10.1124/dmd.110.032474

  3. Komoto, Ikumi

    1. The N-Oxide Metabolite Contributes to Bladder Selectivity Resulting from Oral Propiverine: Muscarinic Receptor Binding and Pharmacokinetics
      Shizuo Yamada, Yoshihiko Ito, Yuko Taki, Masanao Seki, Masato Nanri, Fumiaki Yamashita, Kayo Morishita, Ikumi Komoto and Ken-ichiro Yoshida
      Drug Metabolism and Disposition August 2010, 38 (8) 1314-1321; DOI: https://doi.org/10.1124/dmd.110.033233

  4. Kusama, Makiko

    1. In Silico Classification of Major Clearance Pathways of Drugs with Their Physiochemical Parameters
      Makiko Kusama, Kouta Toshimoto, Kazuya Maeda, Yuka Hirai, Satoki Imai, Koji Chiba, Yutaka Akiyama and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2010, 38 (8) 1362-1370; DOI: https://doi.org/10.1124/dmd.110.032789

L

  1. Li, Yi

    1. Central Nervous System Penetration for Small Molecule Therapeutic Agents Does Not Increase in Multiple Sclerosis- and Alzheimer's Disease-Related Animal Models Despite Reported Blood-Brain Barrier Disruption
      Ziqiang Cheng, Jinqiang Zhang, Houfu Liu, Yi Li, Yonggang Zhao and Eric Yang
      Drug Metabolism and Disposition August 2010, 38 (8) 1355-1361; DOI: https://doi.org/10.1124/dmd.110.033324

  2. Li, Yu

    1. Species-Specific Metabolism of SGX523 by Aldehyde Oxidase and the Toxicological Implications
      Sharon Diamond, Jason Boer, Thomas P. Maduskuie, Nikoo Falahatpisheh, Yu Li and Swamy Yeleswaram
      Drug Metabolism and Disposition August 2010, 38 (8) 1277-1285; DOI: https://doi.org/10.1124/dmd.110.032375

  3. Liu, Houfu

    1. Central Nervous System Penetration for Small Molecule Therapeutic Agents Does Not Increase in Multiple Sclerosis- and Alzheimer's Disease-Related Animal Models Despite Reported Blood-Brain Barrier Disruption
      Ziqiang Cheng, Jinqiang Zhang, Houfu Liu, Yi Li, Yonggang Zhao and Eric Yang
      Drug Metabolism and Disposition August 2010, 38 (8) 1355-1361; DOI: https://doi.org/10.1124/dmd.110.033324

  4. Lu, Wenjie Jessie

    1. Methadone: A Substrate and Mechanism-Based Inhibitor of CYP19 (Aromatase)
      Wenjie Jessie Lu, Robert Bies, Landry K. Kamden, Zeruesenay Desta and David A. Flockhart
      Drug Metabolism and Disposition August 2010, 38 (8) 1308-1313; DOI: https://doi.org/10.1124/dmd.110.032474

M

  1. Maduskuie, Thomas P.

    1. Species-Specific Metabolism of SGX523 by Aldehyde Oxidase and the Toxicological Implications
      Sharon Diamond, Jason Boer, Thomas P. Maduskuie, Nikoo Falahatpisheh, Yu Li and Swamy Yeleswaram
      Drug Metabolism and Disposition August 2010, 38 (8) 1277-1285; DOI: https://doi.org/10.1124/dmd.110.032375

  2. Maeda, Kazuya

    1. In Silico Classification of Major Clearance Pathways of Drugs with Their Physiochemical Parameters
      Makiko Kusama, Kouta Toshimoto, Kazuya Maeda, Yuka Hirai, Satoki Imai, Koji Chiba, Yutaka Akiyama and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2010, 38 (8) 1362-1370; DOI: https://doi.org/10.1124/dmd.110.032789

  3. Matsushima, Eiji

    1. Formation Pathways of γ-Butyrolactone from the Furan Ring of Tegafur during Its Conversion to 5-Fluorouracil
      Ikuo Yamamiya, Kunihiro Yoshisue, Eiji Matsushima and Sekio Nagayama
      Drug Metabolism and Disposition August 2010, 38 (8) 1267-1276; DOI: https://doi.org/10.1124/dmd.110.032797

  4. Miyazaki, Makoto

    1. Furanocoumarin Derivatives in Kampo Extract Medicines Inhibit Cytochrome P450 3A4 and P-Glycoprotein
      Kazunori Iwanaga, Manami Hayashi, Yukimi Hamahata, Makoto Miyazaki, Makio Shibano, Masahiko Taniguchi, Kimiye Baba and Masawo Kakemi
      Drug Metabolism and Disposition August 2010, 38 (8) 1286-1294; DOI: https://doi.org/10.1124/dmd.110.032847

  5. Morishita, Kayo

    1. The N-Oxide Metabolite Contributes to Bladder Selectivity Resulting from Oral Propiverine: Muscarinic Receptor Binding and Pharmacokinetics
      Shizuo Yamada, Yoshihiko Ito, Yuko Taki, Masanao Seki, Masato Nanri, Fumiaki Yamashita, Kayo Morishita, Ikumi Komoto and Ken-ichiro Yoshida
      Drug Metabolism and Disposition August 2010, 38 (8) 1314-1321; DOI: https://doi.org/10.1124/dmd.110.033233

N

  1. Nagar, Swati

    1. Identification of Novel Metoclopramide Metabolites in Humans: In Vitro and In Vivo Studies
      Upendra A. Argikar, Javier Gomez, Din Ung, Henry P. Parkman and Swati Nagar
      Drug Metabolism and Disposition August 2010, 38 (8) 1295-1307; DOI: https://doi.org/10.1124/dmd.110.033357

  2. Nagayama, Sekio

    1. Formation Pathways of γ-Butyrolactone from the Furan Ring of Tegafur during Its Conversion to 5-Fluorouracil
      Ikuo Yamamiya, Kunihiro Yoshisue, Eiji Matsushima and Sekio Nagayama
      Drug Metabolism and Disposition August 2010, 38 (8) 1267-1276; DOI: https://doi.org/10.1124/dmd.110.032797

  3. Nanri, Masato

    1. The N-Oxide Metabolite Contributes to Bladder Selectivity Resulting from Oral Propiverine: Muscarinic Receptor Binding and Pharmacokinetics
      Shizuo Yamada, Yoshihiko Ito, Yuko Taki, Masanao Seki, Masato Nanri, Fumiaki Yamashita, Kayo Morishita, Ikumi Komoto and Ken-ichiro Yoshida
      Drug Metabolism and Disposition August 2010, 38 (8) 1314-1321; DOI: https://doi.org/10.1124/dmd.110.033233

  4. Neubauer, Andreas

    1. Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib
      Marius Dohse, Christian Scharenberg, Suneet Shukla, Robert W. Robey, Thorsten Volkmann, John F. Deeken, Cornelia Brendel, Suresh V. Ambudkar, Andreas Neubauer and Susan E. Bates
      Drug Metabolism and Disposition August 2010, 38 (8) 1371-1380; DOI: https://doi.org/10.1124/dmd.109.031302

O

  1. Obach, R. Scott

    1. In Vitro-In Vivo Correlation for Intrinsic Clearance for Drugs Metabolized by Human Aldehyde Oxidase
      Michael Zientek, Ying Jiang, Kuresh Youdim and R. Scott Obach
      Drug Metabolism and Disposition August 2010, 38 (8) 1322-1327; DOI: https://doi.org/10.1124/dmd.110.033555
    2. Metabolism of Ramelteon in Human Liver Microsomes and Correlation with the Effect of Fluvoxamine on Ramelteon Pharmacokinetics
      R. Scott Obach and Tim F. Ryder
      Drug Metabolism and Disposition August 2010, 38 (8) 1381-1391; DOI: https://doi.org/10.1124/dmd.110.034009

  2. Olsen, Lars

    1. Computational Prediction of Binding Affinity for CYP1A2-Ligand Complexes Using Empirical Free Energy Calculations
      Poongavanam Vasanthanathan, Lars Olsen, Flemming Steen Jørgensen, Nico P. E. Vermeulen and Chris Oostenbrink
      Drug Metabolism and Disposition August 2010, 38 (8) 1347-1354; DOI: https://doi.org/10.1124/dmd.110.032946

  3. Oostenbrink, Chris

    1. Computational Prediction of Binding Affinity for CYP1A2-Ligand Complexes Using Empirical Free Energy Calculations
      Poongavanam Vasanthanathan, Lars Olsen, Flemming Steen Jørgensen, Nico P. E. Vermeulen and Chris Oostenbrink
      Drug Metabolism and Disposition August 2010, 38 (8) 1347-1354; DOI: https://doi.org/10.1124/dmd.110.032946

P

  1. Parkman, Henry P.

    1. Identification of Novel Metoclopramide Metabolites in Humans: In Vitro and In Vivo Studies
      Upendra A. Argikar, Javier Gomez, Din Ung, Henry P. Parkman and Swati Nagar
      Drug Metabolism and Disposition August 2010, 38 (8) 1295-1307; DOI: https://doi.org/10.1124/dmd.110.033357

R

  1. Radtke, M.

    1. In Vitro to In Vivo Comparison of the Substrate Characteristics of Sorafenib Tosylate toward P-Glycoprotein
      M. J. Gnoth, S. Sandmann, K. Engel and M. Radtke
      Drug Metabolism and Disposition August 2010, 38 (8) 1341-1346; DOI: https://doi.org/10.1124/dmd.110.032052

  2. Redfern, Chris P. F.

    1. Relevance of Nonsynonymous CYP2C8 Polymorphisms to 13-cis Retinoic Acid and Paclitaxel Hydroxylation
      Sophie E. Rowbotham, Alan V. Boddy, Chris P. F. Redfern, Gareth J. Veal and Ann K. Daly
      Drug Metabolism and Disposition August 2010, 38 (8) 1261-1266; DOI: https://doi.org/10.1124/dmd.109.030866

  3. Robey, Robert W.

    1. Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib
      Marius Dohse, Christian Scharenberg, Suneet Shukla, Robert W. Robey, Thorsten Volkmann, John F. Deeken, Cornelia Brendel, Suresh V. Ambudkar, Andreas Neubauer and Susan E. Bates
      Drug Metabolism and Disposition August 2010, 38 (8) 1371-1380; DOI: https://doi.org/10.1124/dmd.109.031302

  4. Rowbotham, Sophie E.

    1. Relevance of Nonsynonymous CYP2C8 Polymorphisms to 13-cis Retinoic Acid and Paclitaxel Hydroxylation
      Sophie E. Rowbotham, Alan V. Boddy, Chris P. F. Redfern, Gareth J. Veal and Ann K. Daly
      Drug Metabolism and Disposition August 2010, 38 (8) 1261-1266; DOI: https://doi.org/10.1124/dmd.109.030866

  5. Ryder, Tim F.

    1. Metabolism of Ramelteon in Human Liver Microsomes and Correlation with the Effect of Fluvoxamine on Ramelteon Pharmacokinetics
      R. Scott Obach and Tim F. Ryder
      Drug Metabolism and Disposition August 2010, 38 (8) 1381-1391; DOI: https://doi.org/10.1124/dmd.110.034009

S

  1. Sandmann, S.

    1. In Vitro to In Vivo Comparison of the Substrate Characteristics of Sorafenib Tosylate toward P-Glycoprotein
      M. J. Gnoth, S. Sandmann, K. Engel and M. Radtke
      Drug Metabolism and Disposition August 2010, 38 (8) 1341-1346; DOI: https://doi.org/10.1124/dmd.110.032052

  2. Scharenberg, Christian

    1. Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib
      Marius Dohse, Christian Scharenberg, Suneet Shukla, Robert W. Robey, Thorsten Volkmann, John F. Deeken, Cornelia Brendel, Suresh V. Ambudkar, Andreas Neubauer and Susan E. Bates
      Drug Metabolism and Disposition August 2010, 38 (8) 1371-1380; DOI: https://doi.org/10.1124/dmd.109.031302

  3. Seki, Masanao

    1. The N-Oxide Metabolite Contributes to Bladder Selectivity Resulting from Oral Propiverine: Muscarinic Receptor Binding and Pharmacokinetics
      Shizuo Yamada, Yoshihiko Ito, Yuko Taki, Masanao Seki, Masato Nanri, Fumiaki Yamashita, Kayo Morishita, Ikumi Komoto and Ken-ichiro Yoshida
      Drug Metabolism and Disposition August 2010, 38 (8) 1314-1321; DOI: https://doi.org/10.1124/dmd.110.033233

  4. Shibano, Makio

    1. Furanocoumarin Derivatives in Kampo Extract Medicines Inhibit Cytochrome P450 3A4 and P-Glycoprotein
      Kazunori Iwanaga, Manami Hayashi, Yukimi Hamahata, Makoto Miyazaki, Makio Shibano, Masahiko Taniguchi, Kimiye Baba and Masawo Kakemi
      Drug Metabolism and Disposition August 2010, 38 (8) 1286-1294; DOI: https://doi.org/10.1124/dmd.110.032847

  5. Shukla, Suneet

    1. Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib
      Marius Dohse, Christian Scharenberg, Suneet Shukla, Robert W. Robey, Thorsten Volkmann, John F. Deeken, Cornelia Brendel, Suresh V. Ambudkar, Andreas Neubauer and Susan E. Bates
      Drug Metabolism and Disposition August 2010, 38 (8) 1371-1380; DOI: https://doi.org/10.1124/dmd.109.031302

  6. Sugiyama, Yuichi

    1. In Silico Classification of Major Clearance Pathways of Drugs with Their Physiochemical Parameters
      Makiko Kusama, Kouta Toshimoto, Kazuya Maeda, Yuka Hirai, Satoki Imai, Koji Chiba, Yutaka Akiyama and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2010, 38 (8) 1362-1370; DOI: https://doi.org/10.1124/dmd.110.032789

T

  1. Taki, Yuko

    1. The N-Oxide Metabolite Contributes to Bladder Selectivity Resulting from Oral Propiverine: Muscarinic Receptor Binding and Pharmacokinetics
      Shizuo Yamada, Yoshihiko Ito, Yuko Taki, Masanao Seki, Masato Nanri, Fumiaki Yamashita, Kayo Morishita, Ikumi Komoto and Ken-ichiro Yoshida
      Drug Metabolism and Disposition August 2010, 38 (8) 1314-1321; DOI: https://doi.org/10.1124/dmd.110.033233

  2. Taniguchi, Masahiko

    1. Furanocoumarin Derivatives in Kampo Extract Medicines Inhibit Cytochrome P450 3A4 and P-Glycoprotein
      Kazunori Iwanaga, Manami Hayashi, Yukimi Hamahata, Makoto Miyazaki, Makio Shibano, Masahiko Taniguchi, Kimiye Baba and Masawo Kakemi
      Drug Metabolism and Disposition August 2010, 38 (8) 1286-1294; DOI: https://doi.org/10.1124/dmd.110.032847

  3. Toshimoto, Kouta

    1. In Silico Classification of Major Clearance Pathways of Drugs with Their Physiochemical Parameters
      Makiko Kusama, Kouta Toshimoto, Kazuya Maeda, Yuka Hirai, Satoki Imai, Koji Chiba, Yutaka Akiyama and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2010, 38 (8) 1362-1370; DOI: https://doi.org/10.1124/dmd.110.032789

U

  1. Ung, Din

    1. Identification of Novel Metoclopramide Metabolites in Humans: In Vitro and In Vivo Studies
      Upendra A. Argikar, Javier Gomez, Din Ung, Henry P. Parkman and Swati Nagar
      Drug Metabolism and Disposition August 2010, 38 (8) 1295-1307; DOI: https://doi.org/10.1124/dmd.110.033357

V

  1. Vasanthanathan, Poongavanam

    1. Computational Prediction of Binding Affinity for CYP1A2-Ligand Complexes Using Empirical Free Energy Calculations
      Poongavanam Vasanthanathan, Lars Olsen, Flemming Steen Jørgensen, Nico P. E. Vermeulen and Chris Oostenbrink
      Drug Metabolism and Disposition August 2010, 38 (8) 1347-1354; DOI: https://doi.org/10.1124/dmd.110.032946

  2. Veal, Gareth J.

    1. Relevance of Nonsynonymous CYP2C8 Polymorphisms to 13-cis Retinoic Acid and Paclitaxel Hydroxylation
      Sophie E. Rowbotham, Alan V. Boddy, Chris P. F. Redfern, Gareth J. Veal and Ann K. Daly
      Drug Metabolism and Disposition August 2010, 38 (8) 1261-1266; DOI: https://doi.org/10.1124/dmd.109.030866

  3. Vermeulen, Nico P. E.

    1. Computational Prediction of Binding Affinity for CYP1A2-Ligand Complexes Using Empirical Free Energy Calculations
      Poongavanam Vasanthanathan, Lars Olsen, Flemming Steen Jørgensen, Nico P. E. Vermeulen and Chris Oostenbrink
      Drug Metabolism and Disposition August 2010, 38 (8) 1347-1354; DOI: https://doi.org/10.1124/dmd.110.032946

  4. Volkmann, Thorsten

    1. Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib
      Marius Dohse, Christian Scharenberg, Suneet Shukla, Robert W. Robey, Thorsten Volkmann, John F. Deeken, Cornelia Brendel, Suresh V. Ambudkar, Andreas Neubauer and Susan E. Bates
      Drug Metabolism and Disposition August 2010, 38 (8) 1371-1380; DOI: https://doi.org/10.1124/dmd.109.031302

Y

  1. Yamada, Shizuo

    1. The N-Oxide Metabolite Contributes to Bladder Selectivity Resulting from Oral Propiverine: Muscarinic Receptor Binding and Pharmacokinetics
      Shizuo Yamada, Yoshihiko Ito, Yuko Taki, Masanao Seki, Masato Nanri, Fumiaki Yamashita, Kayo Morishita, Ikumi Komoto and Ken-ichiro Yoshida
      Drug Metabolism and Disposition August 2010, 38 (8) 1314-1321; DOI: https://doi.org/10.1124/dmd.110.033233

  2. Yamamiya, Ikuo

    1. Formation Pathways of γ-Butyrolactone from the Furan Ring of Tegafur during Its Conversion to 5-Fluorouracil
      Ikuo Yamamiya, Kunihiro Yoshisue, Eiji Matsushima and Sekio Nagayama
      Drug Metabolism and Disposition August 2010, 38 (8) 1267-1276; DOI: https://doi.org/10.1124/dmd.110.032797

  3. Yamashita, Fumiaki

    1. The N-Oxide Metabolite Contributes to Bladder Selectivity Resulting from Oral Propiverine: Muscarinic Receptor Binding and Pharmacokinetics
      Shizuo Yamada, Yoshihiko Ito, Yuko Taki, Masanao Seki, Masato Nanri, Fumiaki Yamashita, Kayo Morishita, Ikumi Komoto and Ken-ichiro Yoshida
      Drug Metabolism and Disposition August 2010, 38 (8) 1314-1321; DOI: https://doi.org/10.1124/dmd.110.033233

  4. Yang, Eric

    1. Central Nervous System Penetration for Small Molecule Therapeutic Agents Does Not Increase in Multiple Sclerosis- and Alzheimer's Disease-Related Animal Models Despite Reported Blood-Brain Barrier Disruption
      Ziqiang Cheng, Jinqiang Zhang, Houfu Liu, Yi Li, Yonggang Zhao and Eric Yang
      Drug Metabolism and Disposition August 2010, 38 (8) 1355-1361; DOI: https://doi.org/10.1124/dmd.110.033324

  5. Yeleswaram, Swamy

    1. Species-Specific Metabolism of SGX523 by Aldehyde Oxidase and the Toxicological Implications
      Sharon Diamond, Jason Boer, Thomas P. Maduskuie, Nikoo Falahatpisheh, Yu Li and Swamy Yeleswaram
      Drug Metabolism and Disposition August 2010, 38 (8) 1277-1285; DOI: https://doi.org/10.1124/dmd.110.032375

  6. Yoshida, Ken-ichiro

    1. The N-Oxide Metabolite Contributes to Bladder Selectivity Resulting from Oral Propiverine: Muscarinic Receptor Binding and Pharmacokinetics
      Shizuo Yamada, Yoshihiko Ito, Yuko Taki, Masanao Seki, Masato Nanri, Fumiaki Yamashita, Kayo Morishita, Ikumi Komoto and Ken-ichiro Yoshida
      Drug Metabolism and Disposition August 2010, 38 (8) 1314-1321; DOI: https://doi.org/10.1124/dmd.110.033233

  7. Yoshisue, Kunihiro

    1. Formation Pathways of γ-Butyrolactone from the Furan Ring of Tegafur during Its Conversion to 5-Fluorouracil
      Ikuo Yamamiya, Kunihiro Yoshisue, Eiji Matsushima and Sekio Nagayama
      Drug Metabolism and Disposition August 2010, 38 (8) 1267-1276; DOI: https://doi.org/10.1124/dmd.110.032797

  8. Youdim, Kuresh

    1. In Vitro-In Vivo Correlation for Intrinsic Clearance for Drugs Metabolized by Human Aldehyde Oxidase
      Michael Zientek, Ying Jiang, Kuresh Youdim and R. Scott Obach
      Drug Metabolism and Disposition August 2010, 38 (8) 1322-1327; DOI: https://doi.org/10.1124/dmd.110.033555

Z

  1. Zhang, Jinqiang

    1. Central Nervous System Penetration for Small Molecule Therapeutic Agents Does Not Increase in Multiple Sclerosis- and Alzheimer's Disease-Related Animal Models Despite Reported Blood-Brain Barrier Disruption
      Ziqiang Cheng, Jinqiang Zhang, Houfu Liu, Yi Li, Yonggang Zhao and Eric Yang
      Drug Metabolism and Disposition August 2010, 38 (8) 1355-1361; DOI: https://doi.org/10.1124/dmd.110.033324

  2. Zhao, Yonggang

    1. Central Nervous System Penetration for Small Molecule Therapeutic Agents Does Not Increase in Multiple Sclerosis- and Alzheimer's Disease-Related Animal Models Despite Reported Blood-Brain Barrier Disruption
      Ziqiang Cheng, Jinqiang Zhang, Houfu Liu, Yi Li, Yonggang Zhao and Eric Yang
      Drug Metabolism and Disposition August 2010, 38 (8) 1355-1361; DOI: https://doi.org/10.1124/dmd.110.033324

  3. Zhong, Dafang

    1. Metabolism of Flumatinib, a Novel Antineoplastic Tyrosine Kinase Inhibitor, in Chronic Myelogenous Leukemia Patients
      Aishen Gong, Xiaoyan Chen, Pan Deng and Dafang Zhong
      Drug Metabolism and Disposition August 2010, 38 (8) 1328-1340; DOI: https://doi.org/10.1124/dmd.110.032326

  4. Zientek, Michael

    1. In Vitro-In Vivo Correlation for Intrinsic Clearance for Drugs Metabolized by Human Aldehyde Oxidase
      Michael Zientek, Ying Jiang, Kuresh Youdim and R. Scott Obach
      Drug Metabolism and Disposition August 2010, 38 (8) 1322-1327; DOI: https://doi.org/10.1124/dmd.110.033555
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