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Index by author

January 01, 2011; Volume 39,Issue 1

A

  1. Ačimovič, Jure

    1. Inhibition of Human Sterol Δ7-Reductase and Other Postlanosterol Enzymes by LK-980, a Novel Inhibitor of Cholesterol Synthesis
      Jure Ačimovič, Tina Korošec, Matej Seliškar, Ingemar Bjorkhem, Katalin Monostory, Pal Szabo, Jean-Marc Pascussi, Ales Belič, Uroš Urleb, Darko Kocjan and Damjana Rozman
      Drug Metabolism and Disposition January 2011, 39 (1) 39-46; DOI: https://doi.org/10.1124/dmd.110.035840

  2. Ahn, Taeho

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

  3. Alton, Kevin B.

    1. Identification of Human Liver Cytochrome P450 Enzymes Involved in the Metabolism of SCH 530348 (Vorapaxar), a Potent Oral Thrombin Protease-Activated Receptor 1 Antagonist
      Anima Ghosal, Xiaowen Lu, Natalia Penner, Lan Gao, Ragu Ramanathan, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition January 2011, 39 (1) 30-38; DOI: https://doi.org/10.1124/dmd.110.035493

  4. Amano, Nobuyuki

    1. Quantitative Investigation of the Impact of P-Glycoprotein Inhibition on Drug Transport across Blood-Brain Barrier in Rats
      Hiroshi Sugimoto, Hideki Hirabayashi, Yoshiaki Kimura, Atsutoshi Furuta, Nobuyuki Amano and Toshiya Moriwaki
      Drug Metabolism and Disposition January 2011, 39 (1) 8-14; DOI: https://doi.org/10.1124/dmd.110.035774

  5. Auld, Douglas S.

    1. Identification of Clinically Used Drugs That Activate Pregnane X Receptors
      Sunita J. Shukla, Srilatha Sakamuru, Ruili Huang, Timothy A. Moeller, Paul Shinn, Danielle VanLeer, Douglas S. Auld, Christopher P. Austin and Menghang Xia
      Drug Metabolism and Disposition January 2011, 39 (1) 151-159; DOI: https://doi.org/10.1124/dmd.110.035105

  6. Austin, Christopher P.

    1. Identification of Clinically Used Drugs That Activate Pregnane X Receptors
      Sunita J. Shukla, Srilatha Sakamuru, Ruili Huang, Timothy A. Moeller, Paul Shinn, Danielle VanLeer, Douglas S. Auld, Christopher P. Austin and Menghang Xia
      Drug Metabolism and Disposition January 2011, 39 (1) 151-159; DOI: https://doi.org/10.1124/dmd.110.035105

  7. Azuma, Junichi

    1. Cigarette Smoke Extract Induces CYP2B6 through Constitutive Androstane Receptor in Hepatocytes
      Ikumi Washio, Makiko Maeda, Chika Sugiura, Ryota Shiga, Mitsuhiro Yoshida, Shinpei Nonen, Yasushi Fujio and Junichi Azuma
      Drug Metabolism and Disposition January 2011, 39 (1) 1-3; DOI: https://doi.org/10.1124/dmd.110.034504

B

  1. Babalola, Kathlene

    1. Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
      Abdul Mutlib, Robert Espina, Karthick Vishwanathan, Kathlene Babalola, Zecheng Chen, Christoph Dehnhardt, Aranapakam Venkatesan, Tarek Mansour, Inder Chaudhary, Rasmy Talaat and JoAnn Scatina
      Drug Metabolism and Disposition January 2011, 39 (1) 106-116; DOI: https://doi.org/10.1124/dmd.110.032490

  2. Belič, Ales

    1. Inhibition of Human Sterol Δ7-Reductase and Other Postlanosterol Enzymes by LK-980, a Novel Inhibitor of Cholesterol Synthesis
      Jure Ačimovič, Tina Korošec, Matej Seliškar, Ingemar Bjorkhem, Katalin Monostory, Pal Szabo, Jean-Marc Pascussi, Ales Belič, Uroš Urleb, Darko Kocjan and Damjana Rozman
      Drug Metabolism and Disposition January 2011, 39 (1) 39-46; DOI: https://doi.org/10.1124/dmd.110.035840

  3. Bi, Yi-an

    1. Characterization of Digoxin Uptake in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Jonathan Chupka, Yongling Xiao, Yi-an Bi and David B. Duignan
      Drug Metabolism and Disposition January 2011, 39 (1) 47-53; DOI: https://doi.org/10.1124/dmd.110.034298

  4. Bjorkhem, Ingemar

    1. Inhibition of Human Sterol Δ7-Reductase and Other Postlanosterol Enzymes by LK-980, a Novel Inhibitor of Cholesterol Synthesis
      Jure Ačimovič, Tina Korošec, Matej Seliškar, Ingemar Bjorkhem, Katalin Monostory, Pal Szabo, Jean-Marc Pascussi, Ales Belič, Uroš Urleb, Darko Kocjan and Damjana Rozman
      Drug Metabolism and Disposition January 2011, 39 (1) 39-46; DOI: https://doi.org/10.1124/dmd.110.035840

  5. Boado, Ruben J.

    1. Brain-Penetrating Tumor Necrosis Factor Decoy Receptor in the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition January 2011, 39 (1) 71-76; DOI: https://doi.org/10.1124/dmd.110.036012

  6. Boulos, Nidal

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  7. Butcher, Neville J.

    1. Histone Deacetylase Inhibitors Increase Human Arylamine N-Acetyltransferase-1 Expression in Human Tumor Cells
      Scott Paterson, Kok L. Sin, Jacky M. Tiang, Rodney F. Minchin and Neville J. Butcher
      Drug Metabolism and Disposition January 2011, 39 (1) 77-82; DOI: https://doi.org/10.1124/dmd.110.036202

C

  1. Chaudhary, Inder

    1. Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
      Abdul Mutlib, Robert Espina, Karthick Vishwanathan, Kathlene Babalola, Zecheng Chen, Christoph Dehnhardt, Aranapakam Venkatesan, Tarek Mansour, Inder Chaudhary, Rasmy Talaat and JoAnn Scatina
      Drug Metabolism and Disposition January 2011, 39 (1) 106-116; DOI: https://doi.org/10.1124/dmd.110.032490

  2. Chen, Stephanie

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

  3. Chen, Zecheng

    1. Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
      Abdul Mutlib, Robert Espina, Karthick Vishwanathan, Kathlene Babalola, Zecheng Chen, Christoph Dehnhardt, Aranapakam Venkatesan, Tarek Mansour, Inder Chaudhary, Rasmy Talaat and JoAnn Scatina
      Drug Metabolism and Disposition January 2011, 39 (1) 106-116; DOI: https://doi.org/10.1124/dmd.110.032490

  4. Cheng, Peter T.

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

  5. Cho, Joo-Youn

    1. Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin
      Jae Yong Chung, Joo-Youn Cho, Hyeong-Seok Lim, Jung-Ryul Kim, Kyung-Sang Yu, Kyoung Soo Lim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition January 2011, 39 (1) 92-97; DOI: https://doi.org/10.1124/dmd.110.035246

  6. Chowdhury, Swapan K.

    1. Identification of Human Liver Cytochrome P450 Enzymes Involved in the Metabolism of SCH 530348 (Vorapaxar), a Potent Oral Thrombin Protease-Activated Receptor 1 Antagonist
      Anima Ghosal, Xiaowen Lu, Natalia Penner, Lan Gao, Ragu Ramanathan, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition January 2011, 39 (1) 30-38; DOI: https://doi.org/10.1124/dmd.110.035493

  7. Chung, Jae Yong

    1. Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin
      Jae Yong Chung, Joo-Youn Cho, Hyeong-Seok Lim, Jung-Ryul Kim, Kyung-Sang Yu, Kyoung Soo Lim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition January 2011, 39 (1) 92-97; DOI: https://doi.org/10.1124/dmd.110.035246

  8. Chupka, Jonathan

    1. Characterization of Digoxin Uptake in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Jonathan Chupka, Yongling Xiao, Yi-an Bi and David B. Duignan
      Drug Metabolism and Disposition January 2011, 39 (1) 47-53; DOI: https://doi.org/10.1124/dmd.110.034298

D

  1. Dehnhardt, Christoph

    1. Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
      Abdul Mutlib, Robert Espina, Karthick Vishwanathan, Kathlene Babalola, Zecheng Chen, Christoph Dehnhardt, Aranapakam Venkatesan, Tarek Mansour, Inder Chaudhary, Rasmy Talaat and JoAnn Scatina
      Drug Metabolism and Disposition January 2011, 39 (1) 106-116; DOI: https://doi.org/10.1124/dmd.110.032490

  2. Deng, Yangmei

    1. Activation of the Acute Inflammatory Response Alters Cytochrome P450 Expression and Eicosanoid Metabolism
      Katherine N. Theken, Yangmei Deng, M. Alison Kannon, Tricia M. Miller, Samuel M. Poloyac and Craig R. Lee
      Drug Metabolism and Disposition January 2011, 39 (1) 22-29; DOI: https://doi.org/10.1124/dmd.110.035287

  3. Desta, Zeruesenay

    1. In Vitro Cytochrome P450-Mediated Metabolism of Exemestane
      Landry K. Kamdem, David A. Flockhart and Zeruesenay Desta
      Drug Metabolism and Disposition January 2011, 39 (1) 98-105; DOI: https://doi.org/10.1124/dmd.110.032276

  4. Dickmann, Leslie

    1. Pregnancy Decreases Rat CYP1A2 Activity and Expression
      Alysa A. Walker, Leslie Dickmann and Nina Isoherranen
      Drug Metabolism and Disposition January 2011, 39 (1) 4-7; DOI: https://doi.org/10.1124/dmd.110.035766

  5. Duignan, David B.

    1. Characterization of Digoxin Uptake in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Jonathan Chupka, Yongling Xiao, Yi-an Bi and David B. Duignan
      Drug Metabolism and Disposition January 2011, 39 (1) 47-53; DOI: https://doi.org/10.1124/dmd.110.034298

  6. Dyer, Michael A.

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

E

  1. Espina, Robert

    1. Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
      Abdul Mutlib, Robert Espina, Karthick Vishwanathan, Kathlene Babalola, Zecheng Chen, Christoph Dehnhardt, Aranapakam Venkatesan, Tarek Mansour, Inder Chaudhary, Rasmy Talaat and JoAnn Scatina
      Drug Metabolism and Disposition January 2011, 39 (1) 106-116; DOI: https://doi.org/10.1124/dmd.110.032490

F

  1. Farah, Nadia

    1. A Baeyer-Villiger Oxidation Specifically Catalyzed by Human Flavin-Containing Monooxygenase 5
      W. George Lai, Nadia Farah, George A. Moniz and Y. Nancy Wong
      Drug Metabolism and Disposition January 2011, 39 (1) 61-70; DOI: https://doi.org/10.1124/dmd.110.035360

  2. Flockhart, David A.

    1. In Vitro Cytochrome P450-Mediated Metabolism of Exemestane
      Landry K. Kamdem, David A. Flockhart and Zeruesenay Desta
      Drug Metabolism and Disposition January 2011, 39 (1) 98-105; DOI: https://doi.org/10.1124/dmd.110.032276

  3. Fujio, Yasushi

    1. Cigarette Smoke Extract Induces CYP2B6 through Constitutive Androstane Receptor in Hepatocytes
      Ikumi Washio, Makiko Maeda, Chika Sugiura, Ryota Shiga, Mitsuhiro Yoshida, Shinpei Nonen, Yasushi Fujio and Junichi Azuma
      Drug Metabolism and Disposition January 2011, 39 (1) 1-3; DOI: https://doi.org/10.1124/dmd.110.034504

  4. Fujiwara, Ryoichi

    1. Toxicological Evaluation of Acyl Glucuronides of Nonsteroidal Anti-Inflammatory Drugs Using Human Embryonic Kidney 293 Cells Stably Expressing Human UDP-Glucuronosyltransferase and Human Hepatocytes
      Toshihisa Koga, Ryoichi Fujiwara, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition January 2011, 39 (1) 54-60; DOI: https://doi.org/10.1124/dmd.110.035600

  5. Furuta, Atsutoshi

    1. Quantitative Investigation of the Impact of P-Glycoprotein Inhibition on Drug Transport across Blood-Brain Barrier in Rats
      Hiroshi Sugimoto, Hideki Hirabayashi, Yoshiaki Kimura, Atsutoshi Furuta, Nobuyuki Amano and Toshiya Moriwaki
      Drug Metabolism and Disposition January 2011, 39 (1) 8-14; DOI: https://doi.org/10.1124/dmd.110.035774

G

  1. Gao, Lan

    1. Identification of Human Liver Cytochrome P450 Enzymes Involved in the Metabolism of SCH 530348 (Vorapaxar), a Potent Oral Thrombin Protease-Activated Receptor 1 Antagonist
      Anima Ghosal, Xiaowen Lu, Natalia Penner, Lan Gao, Ragu Ramanathan, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition January 2011, 39 (1) 30-38; DOI: https://doi.org/10.1124/dmd.110.035493

  2. Ghosal, Anima

    1. Identification of Human Liver Cytochrome P450 Enzymes Involved in the Metabolism of SCH 530348 (Vorapaxar), a Potent Oral Thrombin Protease-Activated Receptor 1 Antagonist
      Anima Ghosal, Xiaowen Lu, Natalia Penner, Lan Gao, Ragu Ramanathan, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition January 2011, 39 (1) 30-38; DOI: https://doi.org/10.1124/dmd.110.035493

  3. Grey, Anne K. Mullen

    1. The Aryl Hydrocarbon Receptor Pathway and the Response to 3-Methylcholanthrene Are Altered in the Liver of Adrenalectomized Rats
      Anne K. Mullen Grey and David S. Riddick
      Drug Metabolism and Disposition January 2011, 39 (1) 83-91; DOI: https://doi.org/10.1124/dmd.110.035584

  4. Grube, Markus

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  5. Guitton, Jérôme

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  6. Guy, R. Kiplin

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

H

  1. Haruta, Tsunemitsu

    1. Organic Cation Transporter-Mediated Renal Secretion of Ipratropium and Tiotropium in Rats and Humans
      Takeo Nakanishi, Tsunemitsu Haruta, Yoshiyuki Shirasaka and Ikumi Tamai
      Drug Metabolism and Disposition January 2011, 39 (1) 117-122; DOI: https://doi.org/10.1124/dmd.110.035402

  2. Hirabayashi, Hideki

    1. Quantitative Investigation of the Impact of P-Glycoprotein Inhibition on Drug Transport across Blood-Brain Barrier in Rats
      Hiroshi Sugimoto, Hideki Hirabayashi, Yoshiaki Kimura, Atsutoshi Furuta, Nobuyuki Amano and Toshiya Moriwaki
      Drug Metabolism and Disposition January 2011, 39 (1) 8-14; DOI: https://doi.org/10.1124/dmd.110.035774

  3. Huang, Ruili

    1. Identification of Clinically Used Drugs That Activate Pregnane X Receptors
      Sunita J. Shukla, Srilatha Sakamuru, Ruili Huang, Timothy A. Moeller, Paul Shinn, Danielle VanLeer, Douglas S. Auld, Christopher P. Austin and Menghang Xia
      Drug Metabolism and Disposition January 2011, 39 (1) 151-159; DOI: https://doi.org/10.1124/dmd.110.035105

  4. Hübner, Tobias

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  5. Hui, Eric Ka-Wai

    1. Brain-Penetrating Tumor Necrosis Factor Decoy Receptor in the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition January 2011, 39 (1) 71-76; DOI: https://doi.org/10.1124/dmd.110.036012

  6. Humphreys, W. Griffith

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

I

  1. Isoherranen, Nina

    1. Pregnancy Decreases Rat CYP1A2 Activity and Expression
      Alysa A. Walker, Leslie Dickmann and Nina Isoherranen
      Drug Metabolism and Disposition January 2011, 39 (1) 4-7; DOI: https://doi.org/10.1124/dmd.110.035766

J

  1. Jang, In-Jin

    1. Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin
      Jae Yong Chung, Joo-Youn Cho, Hyeong-Seok Lim, Jung-Ryul Kim, Kyung-Sang Yu, Kyoung Soo Lim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition January 2011, 39 (1) 92-97; DOI: https://doi.org/10.1124/dmd.110.035246

  2. Jedlitschky, Gabriele

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  3. Jung, Heung-Chae

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

K

  1. Kamdem, Landry K.

    1. In Vitro Cytochrome P450-Mediated Metabolism of Exemestane
      Landry K. Kamdem, David A. Flockhart and Zeruesenay Desta
      Drug Metabolism and Disposition January 2011, 39 (1) 98-105; DOI: https://doi.org/10.1124/dmd.110.032276

  2. Kang, Ji-Yeon

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

  3. Kannon, M. Alison

    1. Activation of the Acute Inflammatory Response Alters Cytochrome P450 Expression and Eicosanoid Metabolism
      Katherine N. Theken, Yangmei Deng, M. Alison Kannon, Tricia M. Miller, Samuel M. Poloyac and Craig R. Lee
      Drug Metabolism and Disposition January 2011, 39 (1) 22-29; DOI: https://doi.org/10.1124/dmd.110.035287

  4. Kim, Dong-Hyun

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

  5. Kim, Dooil

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

  6. Kim, Jung-Ryul

    1. Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin
      Jae Yong Chung, Joo-Youn Cho, Hyeong-Seok Lim, Jung-Ryul Kim, Kyung-Sang Yu, Kyoung Soo Lim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition January 2011, 39 (1) 92-97; DOI: https://doi.org/10.1124/dmd.110.035246

  7. Kim, Keon-Hee

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

  8. Kimoto, Emi

    1. Characterization of Digoxin Uptake in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Jonathan Chupka, Yongling Xiao, Yi-an Bi and David B. Duignan
      Drug Metabolism and Disposition January 2011, 39 (1) 47-53; DOI: https://doi.org/10.1124/dmd.110.034298

  9. Kimura, Yoshiaki

    1. Quantitative Investigation of the Impact of P-Glycoprotein Inhibition on Drug Transport across Blood-Brain Barrier in Rats
      Hiroshi Sugimoto, Hideki Hirabayashi, Yoshiaki Kimura, Atsutoshi Furuta, Nobuyuki Amano and Toshiya Moriwaki
      Drug Metabolism and Disposition January 2011, 39 (1) 8-14; DOI: https://doi.org/10.1124/dmd.110.035774

  10. Kishnani, Narendra S.

    1. Identification of Human Liver Cytochrome P450 Enzymes Involved in the Metabolism of SCH 530348 (Vorapaxar), a Potent Oral Thrombin Protease-Activated Receptor 1 Antagonist
      Anima Ghosal, Xiaowen Lu, Natalia Penner, Lan Gao, Ragu Ramanathan, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition January 2011, 39 (1) 30-38; DOI: https://doi.org/10.1124/dmd.110.035493

  11. Kocjan, Darko

    1. Inhibition of Human Sterol Δ7-Reductase and Other Postlanosterol Enzymes by LK-980, a Novel Inhibitor of Cholesterol Synthesis
      Jure Ačimovič, Tina Korošec, Matej Seliškar, Ingemar Bjorkhem, Katalin Monostory, Pal Szabo, Jean-Marc Pascussi, Ales Belič, Uroš Urleb, Darko Kocjan and Damjana Rozman
      Drug Metabolism and Disposition January 2011, 39 (1) 39-46; DOI: https://doi.org/10.1124/dmd.110.035840

  12. Köck, Kathleen

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  13. Koga, Toshihisa

    1. Toxicological Evaluation of Acyl Glucuronides of Nonsteroidal Anti-Inflammatory Drugs Using Human Embryonic Kidney 293 Cells Stably Expressing Human UDP-Glucuronosyltransferase and Human Hepatocytes
      Toshihisa Koga, Ryoichi Fujiwara, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition January 2011, 39 (1) 54-60; DOI: https://doi.org/10.1124/dmd.110.035600

  14. Korošec, Tina

    1. Inhibition of Human Sterol Δ7-Reductase and Other Postlanosterol Enzymes by LK-980, a Novel Inhibitor of Cholesterol Synthesis
      Jure Ačimovič, Tina Korošec, Matej Seliškar, Ingemar Bjorkhem, Katalin Monostory, Pal Szabo, Jean-Marc Pascussi, Ales Belič, Uroš Urleb, Darko Kocjan and Damjana Rozman
      Drug Metabolism and Disposition January 2011, 39 (1) 39-46; DOI: https://doi.org/10.1124/dmd.110.035840

  15. Kowalczyk, Dariusz W.

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  16. Kroemer, Heyo K.

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

L

  1. Lai, W. George

    1. A Baeyer-Villiger Oxidation Specifically Catalyzed by Human Flavin-Containing Monooxygenase 5
      W. George Lai, Nadia Farah, George A. Moniz and Y. Nancy Wong
      Drug Metabolism and Disposition January 2011, 39 (1) 61-70; DOI: https://doi.org/10.1124/dmd.110.035360

  2. Lee, Craig R.

    1. Activation of the Acute Inflammatory Response Alters Cytochrome P450 Expression and Eicosanoid Metabolism
      Katherine N. Theken, Yangmei Deng, M. Alison Kannon, Tricia M. Miller, Samuel M. Poloyac and Craig R. Lee
      Drug Metabolism and Disposition January 2011, 39 (1) 22-29; DOI: https://doi.org/10.1124/dmd.110.035287

  3. Lee, Young Ju

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

  4. Lerch, Markus M.

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  5. Li, Wenying

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

  6. Lim, Hyeong-Seok

    1. Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin
      Jae Yong Chung, Joo-Youn Cho, Hyeong-Seok Lim, Jung-Ryul Kim, Kyung-Sang Yu, Kyoung Soo Lim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition January 2011, 39 (1) 92-97; DOI: https://doi.org/10.1124/dmd.110.035246

  7. Lim, Kyoung Soo

    1. Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin
      Jae Yong Chung, Joo-Youn Cho, Hyeong-Seok Lim, Jung-Ryul Kim, Kyung-Sang Yu, Kyoung Soo Lim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition January 2011, 39 (1) 92-97; DOI: https://doi.org/10.1124/dmd.110.035246

  8. Lu, Jeff Zhiqiang

    1. Brain-Penetrating Tumor Necrosis Factor Decoy Receptor in the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition January 2011, 39 (1) 71-76; DOI: https://doi.org/10.1124/dmd.110.036012

  9. Lu, Min

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  10. Lu, Xiaowen

    1. Identification of Human Liver Cytochrome P450 Enzymes Involved in the Metabolism of SCH 530348 (Vorapaxar), a Potent Oral Thrombin Protease-Activated Receptor 1 Antagonist
      Anima Ghosal, Xiaowen Lu, Natalia Penner, Lan Gao, Ragu Ramanathan, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition January 2011, 39 (1) 30-38; DOI: https://doi.org/10.1124/dmd.110.035493

M

  1. Maeda, Makiko

    1. Cigarette Smoke Extract Induces CYP2B6 through Constitutive Androstane Receptor in Hepatocytes
      Ikumi Washio, Makiko Maeda, Chika Sugiura, Ryota Shiga, Mitsuhiro Yoshida, Shinpei Nonen, Yasushi Fujio and Junichi Azuma
      Drug Metabolism and Disposition January 2011, 39 (1) 1-3; DOI: https://doi.org/10.1124/dmd.110.034504

  2. Mallari, Jeremy

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  3. Mansour, Tarek

    1. Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
      Abdul Mutlib, Robert Espina, Karthick Vishwanathan, Kathlene Babalola, Zecheng Chen, Christoph Dehnhardt, Aranapakam Venkatesan, Tarek Mansour, Inder Chaudhary, Rasmy Talaat and JoAnn Scatina
      Drug Metabolism and Disposition January 2011, 39 (1) 106-116; DOI: https://doi.org/10.1124/dmd.110.032490

  4. Mayerle, Julia

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  5. Mews, Steffen

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  6. Miller, Laura

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  7. Miller, Tricia M.

    1. Activation of the Acute Inflammatory Response Alters Cytochrome P450 Expression and Eicosanoid Metabolism
      Katherine N. Theken, Yangmei Deng, M. Alison Kannon, Tricia M. Miller, Samuel M. Poloyac and Craig R. Lee
      Drug Metabolism and Disposition January 2011, 39 (1) 22-29; DOI: https://doi.org/10.1124/dmd.110.035287

  8. Minchin, Rodney F.

    1. Histone Deacetylase Inhibitors Increase Human Arylamine N-Acetyltransferase-1 Expression in Human Tumor Cells
      Scott Paterson, Kok L. Sin, Jacky M. Tiang, Rodney F. Minchin and Neville J. Butcher
      Drug Metabolism and Disposition January 2011, 39 (1) 77-82; DOI: https://doi.org/10.1124/dmd.110.036202

  9. Moeller, Timothy A.

    1. Identification of Clinically Used Drugs That Activate Pregnane X Receptors
      Sunita J. Shukla, Srilatha Sakamuru, Ruili Huang, Timothy A. Moeller, Paul Shinn, Danielle VanLeer, Douglas S. Auld, Christopher P. Austin and Menghang Xia
      Drug Metabolism and Disposition January 2011, 39 (1) 151-159; DOI: https://doi.org/10.1124/dmd.110.035105

  10. Moniz, George A.

    1. A Baeyer-Villiger Oxidation Specifically Catalyzed by Human Flavin-Containing Monooxygenase 5
      W. George Lai, Nadia Farah, George A. Moniz and Y. Nancy Wong
      Drug Metabolism and Disposition January 2011, 39 (1) 61-70; DOI: https://doi.org/10.1124/dmd.110.035360

  11. Monostory, Katalin

    1. Inhibition of Human Sterol Δ7-Reductase and Other Postlanosterol Enzymes by LK-980, a Novel Inhibitor of Cholesterol Synthesis
      Jure Ačimovič, Tina Korošec, Matej Seliškar, Ingemar Bjorkhem, Katalin Monostory, Pal Szabo, Jean-Marc Pascussi, Ales Belič, Uroš Urleb, Darko Kocjan and Damjana Rozman
      Drug Metabolism and Disposition January 2011, 39 (1) 39-46; DOI: https://doi.org/10.1124/dmd.110.035840

  12. Moriwaki, Toshiya

    1. Quantitative Investigation of the Impact of P-Glycoprotein Inhibition on Drug Transport across Blood-Brain Barrier in Rats
      Hiroshi Sugimoto, Hideki Hirabayashi, Yoshiaki Kimura, Atsutoshi Furuta, Nobuyuki Amano and Toshiya Moriwaki
      Drug Metabolism and Disposition January 2011, 39 (1) 8-14; DOI: https://doi.org/10.1124/dmd.110.035774

  13. Mutlib, Abdul

    1. Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
      Abdul Mutlib, Robert Espina, Karthick Vishwanathan, Kathlene Babalola, Zecheng Chen, Christoph Dehnhardt, Aranapakam Venkatesan, Tarek Mansour, Inder Chaudhary, Rasmy Talaat and JoAnn Scatina
      Drug Metabolism and Disposition January 2011, 39 (1) 106-116; DOI: https://doi.org/10.1124/dmd.110.032490

N

  1. Nakajima, Miki

    1. Toxicological Evaluation of Acyl Glucuronides of Nonsteroidal Anti-Inflammatory Drugs Using Human Embryonic Kidney 293 Cells Stably Expressing Human UDP-Glucuronosyltransferase and Human Hepatocytes
      Toshihisa Koga, Ryoichi Fujiwara, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition January 2011, 39 (1) 54-60; DOI: https://doi.org/10.1124/dmd.110.035600

  2. Nakanishi, Takeo

    1. Organic Cation Transporter-Mediated Renal Secretion of Ipratropium and Tiotropium in Rats and Humans
      Takeo Nakanishi, Tsunemitsu Haruta, Yoshiyuki Shirasaka and Ikumi Tamai
      Drug Metabolism and Disposition January 2011, 39 (1) 117-122; DOI: https://doi.org/10.1124/dmd.110.035402

  3. Nambaru, Praveen K.

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  4. Nemeth, Katie

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  5. Nonen, Shinpei

    1. Cigarette Smoke Extract Induces CYP2B6 through Constitutive Androstane Receptor in Hepatocytes
      Ikumi Washio, Makiko Maeda, Chika Sugiura, Ryota Shiga, Mitsuhiro Yoshida, Shinpei Nonen, Yasushi Fujio and Junichi Azuma
      Drug Metabolism and Disposition January 2011, 39 (1) 1-3; DOI: https://doi.org/10.1124/dmd.110.034504

O

  1. Obermeier, Mary

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

P

  1. Pan, Jae-Gu

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

  2. Panetta, John C.

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  3. Pardridge, William M.

    1. Brain-Penetrating Tumor Necrosis Factor Decoy Receptor in the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition January 2011, 39 (1) 71-76; DOI: https://doi.org/10.1124/dmd.110.036012

  4. Park, Ki Deok

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

  5. Park, Seon Ha

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

  6. Park, Sun-Ha

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

  7. Pascussi, Jean-Marc

    1. Inhibition of Human Sterol Δ7-Reductase and Other Postlanosterol Enzymes by LK-980, a Novel Inhibitor of Cholesterol Synthesis
      Jure Ačimovič, Tina Korošec, Matej Seliškar, Ingemar Bjorkhem, Katalin Monostory, Pal Szabo, Jean-Marc Pascussi, Ales Belič, Uroš Urleb, Darko Kocjan and Damjana Rozman
      Drug Metabolism and Disposition January 2011, 39 (1) 39-46; DOI: https://doi.org/10.1124/dmd.110.035840

  8. Paterson, Scott

    1. Histone Deacetylase Inhibitors Increase Human Arylamine N-Acetyltransferase-1 Expression in Human Tumor Cells
      Scott Paterson, Kok L. Sin, Jacky M. Tiang, Rodney F. Minchin and Neville J. Butcher
      Drug Metabolism and Disposition January 2011, 39 (1) 77-82; DOI: https://doi.org/10.1124/dmd.110.036202

  9. Payen, Léa

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  10. Penner, Natalia

    1. Identification of Human Liver Cytochrome P450 Enzymes Involved in the Metabolism of SCH 530348 (Vorapaxar), a Potent Oral Thrombin Protease-Activated Receptor 1 Antagonist
      Anima Ghosal, Xiaowen Lu, Natalia Penner, Lan Gao, Ragu Ramanathan, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition January 2011, 39 (1) 30-38; DOI: https://doi.org/10.1124/dmd.110.035493

  11. Poloyac, Samuel M.

    1. Activation of the Acute Inflammatory Response Alters Cytochrome P450 Expression and Eicosanoid Metabolism
      Katherine N. Theken, Yangmei Deng, M. Alison Kannon, Tricia M. Miller, Samuel M. Poloyac and Craig R. Lee
      Drug Metabolism and Disposition January 2011, 39 (1) 22-29; DOI: https://doi.org/10.1124/dmd.110.035287

R

  1. Raghavan, Nirmala

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

  2. Ramanathan, Ragu

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048
    2. Identification of Human Liver Cytochrome P450 Enzymes Involved in the Metabolism of SCH 530348 (Vorapaxar), a Potent Oral Thrombin Protease-Activated Receptor 1 Antagonist
      Anima Ghosal, Xiaowen Lu, Natalia Penner, Lan Gao, Ragu Ramanathan, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition January 2011, 39 (1) 30-38; DOI: https://doi.org/10.1124/dmd.110.035493

  3. Riddick, David S.

    1. The Aryl Hydrocarbon Receptor Pathway and the Response to 3-Methylcholanthrene Are Altered in the Liver of Adrenalectomized Rats
      Anne K. Mullen Grey and David S. Riddick
      Drug Metabolism and Disposition January 2011, 39 (1) 83-91; DOI: https://doi.org/10.1124/dmd.110.035584

  4. Rimmbach, Christian

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  5. Ritter, Christoph A.

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  6. Rosskopf, Dieter

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  7. Roussel, Martine F.

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  8. Rozman, Damjana

    1. Inhibition of Human Sterol Δ7-Reductase and Other Postlanosterol Enzymes by LK-980, a Novel Inhibitor of Cholesterol Synthesis
      Jure Ačimovič, Tina Korošec, Matej Seliškar, Ingemar Bjorkhem, Katalin Monostory, Pal Szabo, Jean-Marc Pascussi, Ales Belič, Uroš Urleb, Darko Kocjan and Damjana Rozman
      Drug Metabolism and Disposition January 2011, 39 (1) 39-46; DOI: https://doi.org/10.1124/dmd.110.035840

S

  1. Sakamuru, Srilatha

    1. Identification of Clinically Used Drugs That Activate Pregnane X Receptors
      Sunita J. Shukla, Srilatha Sakamuru, Ruili Huang, Timothy A. Moeller, Paul Shinn, Danielle VanLeer, Douglas S. Auld, Christopher P. Austin and Menghang Xia
      Drug Metabolism and Disposition January 2011, 39 (1) 151-159; DOI: https://doi.org/10.1124/dmd.110.035105

  2. Scatina, JoAnn

    1. Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
      Abdul Mutlib, Robert Espina, Karthick Vishwanathan, Kathlene Babalola, Zecheng Chen, Christoph Dehnhardt, Aranapakam Venkatesan, Tarek Mansour, Inder Chaudhary, Rasmy Talaat and JoAnn Scatina
      Drug Metabolism and Disposition January 2011, 39 (1) 106-116; DOI: https://doi.org/10.1124/dmd.110.032490

  3. Seliškar, Matej

    1. Inhibition of Human Sterol Δ7-Reductase and Other Postlanosterol Enzymes by LK-980, a Novel Inhibitor of Cholesterol Synthesis
      Jure Ačimovič, Tina Korošec, Matej Seliškar, Ingemar Bjorkhem, Katalin Monostory, Pal Szabo, Jean-Marc Pascussi, Ales Belič, Uroš Urleb, Darko Kocjan and Damjana Rozman
      Drug Metabolism and Disposition January 2011, 39 (1) 39-46; DOI: https://doi.org/10.1124/dmd.110.035840

  4. Sendler, Matthias

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  5. Shiga, Ryota

    1. Cigarette Smoke Extract Induces CYP2B6 through Constitutive Androstane Receptor in Hepatocytes
      Ikumi Washio, Makiko Maeda, Chika Sugiura, Ryota Shiga, Mitsuhiro Yoshida, Shinpei Nonen, Yasushi Fujio and Junichi Azuma
      Drug Metabolism and Disposition January 2011, 39 (1) 1-3; DOI: https://doi.org/10.1124/dmd.110.034504

  6. Shin, Sang-Goo

    1. Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin
      Jae Yong Chung, Joo-Youn Cho, Hyeong-Seok Lim, Jung-Ryul Kim, Kyung-Sang Yu, Kyoung Soo Lim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition January 2011, 39 (1) 92-97; DOI: https://doi.org/10.1124/dmd.110.035246

  7. Shinn, Paul

    1. Identification of Clinically Used Drugs That Activate Pregnane X Receptors
      Sunita J. Shukla, Srilatha Sakamuru, Ruili Huang, Timothy A. Moeller, Paul Shinn, Danielle VanLeer, Douglas S. Auld, Christopher P. Austin and Menghang Xia
      Drug Metabolism and Disposition January 2011, 39 (1) 151-159; DOI: https://doi.org/10.1124/dmd.110.035105

  8. Shirasaka, Yoshiyuki

    1. Organic Cation Transporter-Mediated Renal Secretion of Ipratropium and Tiotropium in Rats and Humans
      Takeo Nakanishi, Tsunemitsu Haruta, Yoshiyuki Shirasaka and Ikumi Tamai
      Drug Metabolism and Disposition January 2011, 39 (1) 117-122; DOI: https://doi.org/10.1124/dmd.110.035402

  9. Shukla, Sunita J.

    1. Identification of Clinically Used Drugs That Activate Pregnane X Receptors
      Sunita J. Shukla, Srilatha Sakamuru, Ruili Huang, Timothy A. Moeller, Paul Shinn, Danielle VanLeer, Douglas S. Auld, Christopher P. Austin and Menghang Xia
      Drug Metabolism and Disposition January 2011, 39 (1) 151-159; DOI: https://doi.org/10.1124/dmd.110.035105

  10. Sin, Kok L.

    1. Histone Deacetylase Inhibitors Increase Human Arylamine N-Acetyltransferase-1 Expression in Human Tumor Cells
      Scott Paterson, Kok L. Sin, Jacky M. Tiang, Rodney F. Minchin and Neville J. Butcher
      Drug Metabolism and Disposition January 2011, 39 (1) 77-82; DOI: https://doi.org/10.1124/dmd.110.036202

  11. Stewart, Clinton F.

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  12. Sugimoto, Hiroshi

    1. Quantitative Investigation of the Impact of P-Glycoprotein Inhibition on Drug Transport across Blood-Brain Barrier in Rats
      Hiroshi Sugimoto, Hideki Hirabayashi, Yoshiaki Kimura, Atsutoshi Furuta, Nobuyuki Amano and Toshiya Moriwaki
      Drug Metabolism and Disposition January 2011, 39 (1) 8-14; DOI: https://doi.org/10.1124/dmd.110.035774

  13. Sugiura, Chika

    1. Cigarette Smoke Extract Induces CYP2B6 through Constitutive Androstane Receptor in Hepatocytes
      Ikumi Washio, Makiko Maeda, Chika Sugiura, Ryota Shiga, Mitsuhiro Yoshida, Shinpei Nonen, Yasushi Fujio and Junichi Azuma
      Drug Metabolism and Disposition January 2011, 39 (1) 1-3; DOI: https://doi.org/10.1124/dmd.110.034504

  14. Szabo, Pal

    1. Inhibition of Human Sterol Δ7-Reductase and Other Postlanosterol Enzymes by LK-980, a Novel Inhibitor of Cholesterol Synthesis
      Jure Ačimovič, Tina Korošec, Matej Seliškar, Ingemar Bjorkhem, Katalin Monostory, Pal Szabo, Jean-Marc Pascussi, Ales Belič, Uroš Urleb, Darko Kocjan and Damjana Rozman
      Drug Metabolism and Disposition January 2011, 39 (1) 39-46; DOI: https://doi.org/10.1124/dmd.110.035840

T

  1. Tagen, Michael

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  2. Talaat, Rasmy

    1. Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
      Abdul Mutlib, Robert Espina, Karthick Vishwanathan, Kathlene Babalola, Zecheng Chen, Christoph Dehnhardt, Aranapakam Venkatesan, Tarek Mansour, Inder Chaudhary, Rasmy Talaat and JoAnn Scatina
      Drug Metabolism and Disposition January 2011, 39 (1) 106-116; DOI: https://doi.org/10.1124/dmd.110.032490

  3. Tamai, Ikumi

    1. Organic Cation Transporter-Mediated Renal Secretion of Ipratropium and Tiotropium in Rats and Humans
      Takeo Nakanishi, Tsunemitsu Haruta, Yoshiyuki Shirasaka and Ikumi Tamai
      Drug Metabolism and Disposition January 2011, 39 (1) 117-122; DOI: https://doi.org/10.1124/dmd.110.035402

  4. Tao, Shiwei

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

  5. Theken, Katherine N.

    1. Activation of the Acute Inflammatory Response Alters Cytochrome P450 Expression and Eicosanoid Metabolism
      Katherine N. Theken, Yangmei Deng, M. Alison Kannon, Tricia M. Miller, Samuel M. Poloyac and Craig R. Lee
      Drug Metabolism and Disposition January 2011, 39 (1) 22-29; DOI: https://doi.org/10.1124/dmd.110.035287

  6. Throm, Stacy

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  7. Tiang, Jacky M.

    1. Histone Deacetylase Inhibitors Increase Human Arylamine N-Acetyltransferase-1 Expression in Human Tumor Cells
      Scott Paterson, Kok L. Sin, Jacky M. Tiang, Rodney F. Minchin and Neville J. Butcher
      Drug Metabolism and Disposition January 2011, 39 (1) 77-82; DOI: https://doi.org/10.1124/dmd.110.036202

U

  1. Urleb, Uroš

    1. Inhibition of Human Sterol Δ7-Reductase and Other Postlanosterol Enzymes by LK-980, a Novel Inhibitor of Cholesterol Synthesis
      Jure Ačimovič, Tina Korošec, Matej Seliškar, Ingemar Bjorkhem, Katalin Monostory, Pal Szabo, Jean-Marc Pascussi, Ales Belič, Uroš Urleb, Darko Kocjan and Damjana Rozman
      Drug Metabolism and Disposition January 2011, 39 (1) 39-46; DOI: https://doi.org/10.1124/dmd.110.035840

V

  1. VanLeer, Danielle

    1. Identification of Clinically Used Drugs That Activate Pregnane X Receptors
      Sunita J. Shukla, Srilatha Sakamuru, Ruili Huang, Timothy A. Moeller, Paul Shinn, Danielle VanLeer, Douglas S. Auld, Christopher P. Austin and Menghang Xia
      Drug Metabolism and Disposition January 2011, 39 (1) 151-159; DOI: https://doi.org/10.1124/dmd.110.035105

  2. Venkatesan, Aranapakam

    1. Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
      Abdul Mutlib, Robert Espina, Karthick Vishwanathan, Kathlene Babalola, Zecheng Chen, Christoph Dehnhardt, Aranapakam Venkatesan, Tarek Mansour, Inder Chaudhary, Rasmy Talaat and JoAnn Scatina
      Drug Metabolism and Disposition January 2011, 39 (1) 106-116; DOI: https://doi.org/10.1124/dmd.110.032490

  3. Vishwanathan, Karthick

    1. Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
      Abdul Mutlib, Robert Espina, Karthick Vishwanathan, Kathlene Babalola, Zecheng Chen, Christoph Dehnhardt, Aranapakam Venkatesan, Tarek Mansour, Inder Chaudhary, Rasmy Talaat and JoAnn Scatina
      Drug Metabolism and Disposition January 2011, 39 (1) 106-116; DOI: https://doi.org/10.1124/dmd.110.032490

W

  1. Walker, Alysa A.

    1. Pregnancy Decreases Rat CYP1A2 Activity and Expression
      Alysa A. Walker, Leslie Dickmann and Nina Isoherranen
      Drug Metabolism and Disposition January 2011, 39 (1) 4-7; DOI: https://doi.org/10.1124/dmd.110.035766

  2. Wang, Lifei

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

  3. Washio, Ikumi

    1. Cigarette Smoke Extract Induces CYP2B6 through Constitutive Androstane Receptor in Hepatocytes
      Ikumi Washio, Makiko Maeda, Chika Sugiura, Ryota Shiga, Mitsuhiro Yoshida, Shinpei Nonen, Yasushi Fujio and Junichi Azuma
      Drug Metabolism and Disposition January 2011, 39 (1) 1-3; DOI: https://doi.org/10.1124/dmd.110.034504

  4. Weiss, Frank U.

    1. Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil
      Praveen K. Nambaru, Tobias Hübner, Kathleen Köck, Steffen Mews, Markus Grube, Léa Payen, Jérôme Guitton, Matthias Sendler, Gabriele Jedlitschky, Christian Rimmbach, Dieter Rosskopf, Dariusz W. Kowalczyk, Heyo K. Kroemer, Frank U. Weiss, Julia Mayerle, Markus M. Lerch and Christoph A. Ritter
      Drug Metabolism and Disposition January 2011, 39 (1) 132-139; DOI: https://doi.org/10.1124/dmd.110.033613

  5. Williams, Richard T.

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  6. Wong, Y. Nancy

    1. A Baeyer-Villiger Oxidation Specifically Catalyzed by Human Flavin-Containing Monooxygenase 5
      W. George Lai, Nadia Farah, George A. Moniz and Y. Nancy Wong
      Drug Metabolism and Disposition January 2011, 39 (1) 61-70; DOI: https://doi.org/10.1124/dmd.110.035360

X

  1. Xia, Menghang

    1. Identification of Clinically Used Drugs That Activate Pregnane X Receptors
      Sunita J. Shukla, Srilatha Sakamuru, Ruili Huang, Timothy A. Moeller, Paul Shinn, Danielle VanLeer, Douglas S. Auld, Christopher P. Austin and Menghang Xia
      Drug Metabolism and Disposition January 2011, 39 (1) 151-159; DOI: https://doi.org/10.1124/dmd.110.035105

  2. Xiao, Yongling

    1. Characterization of Digoxin Uptake in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Jonathan Chupka, Yongling Xiao, Yi-an Bi and David B. Duignan
      Drug Metabolism and Disposition January 2011, 39 (1) 47-53; DOI: https://doi.org/10.1124/dmd.110.034298

  3. Xue, Yongjun

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

Y

  1. Yang, Zheng

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

  2. Yokoi, Tsuyoshi

    1. Toxicological Evaluation of Acyl Glucuronides of Nonsteroidal Anti-Inflammatory Drugs Using Human Embryonic Kidney 293 Cells Stably Expressing Human UDP-Glucuronosyltransferase and Human Hepatocytes
      Toshihisa Koga, Ryoichi Fujiwara, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition January 2011, 39 (1) 54-60; DOI: https://doi.org/10.1124/dmd.110.035600

  3. Yoshida, Mitsuhiro

    1. Cigarette Smoke Extract Induces CYP2B6 through Constitutive Androstane Receptor in Hepatocytes
      Ikumi Washio, Makiko Maeda, Chika Sugiura, Ryota Shiga, Mitsuhiro Yoshida, Shinpei Nonen, Yasushi Fujio and Junichi Azuma
      Drug Metabolism and Disposition January 2011, 39 (1) 1-3; DOI: https://doi.org/10.1124/dmd.110.034504

  4. Yu, Kyung-Sang

    1. Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin
      Jae Yong Chung, Joo-Youn Cho, Hyeong-Seok Lim, Jung-Ryul Kim, Kyung-Sang Yu, Kyoung Soo Lim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition January 2011, 39 (1) 92-97; DOI: https://doi.org/10.1124/dmd.110.035246

  5. Yun, Chul-Ho

    1. Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants
      Keon-Hee Kim, Ji-Yeon Kang, Dong-Hyun Kim, Sun-Ha Park, Seon Ha Park, Dooil Kim, Ki Deok Park, Young Ju Lee, Heung-Chae Jung, Jae-Gu Pan, Taeho Ahn and Chul-Ho Yun
      Drug Metabolism and Disposition January 2011, 39 (1) 140-150; DOI: https://doi.org/10.1124/dmd.110.036392

Z

  1. Zhang, Donglu

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

  2. Zhang, Fan

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  3. Zhang, Hao

    1. Plasma Stability-Dependent Circulation of Acyl Glucuronide Metabolites in Humans: How Circulating Metabolite Profiles of Muraglitazar and Peliglitazar Can Lead to Misleading Risk Assessment
      Donglu Zhang, Nirmala Raghavan, Lifei Wang, Yongjun Xue, Mary Obermeier, Stephanie Chen, Shiwei Tao, Hao Zhang, Peter T. Cheng, Wenying Li, Ragu Ramanathan, Zheng Yang and W. Griffith Humphreys
      Drug Metabolism and Disposition January 2011, 39 (1) 123-131; DOI: https://doi.org/10.1124/dmd.110.035048

  4. Zhang, Jiakun

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915

  5. Zhou, Qing-Hui

    1. Brain-Penetrating Tumor Necrosis Factor Decoy Receptor in the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition January 2011, 39 (1) 71-76; DOI: https://doi.org/10.1124/dmd.110.036012

  6. Zhu, Fangyi

    1. Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
      Fan Zhang, Michael Tagen, Stacy Throm, Jeremy Mallari, Laura Miller, R. Kiplin Guy, Michael A. Dyer, Richard T. Williams, Martine F. Roussel, Katie Nemeth, Fangyi Zhu, Jiakun Zhang, Min Lu, John C. Panetta, Nidal Boulos and Clinton F. Stewart
      Drug Metabolism and Disposition January 2011, 39 (1) 15-21; DOI: https://doi.org/10.1124/dmd.110.035915
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