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Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840