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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

October 01, 2011; Volume 39,Issue 10
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Ahn, Sunjoo

    1. You have access
      Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability
      Chien-Ming Li, Jianjun Chen, Yan Lu, Ramesh Narayanan, Deanna N. Parke, Wei Li, Sunjoo Ahn, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition October 2011, 39 (10) 1833-1839; DOI: https://doi.org/10.1124/dmd.110.036616
  2. Anger, Gregory J.

    1. You have access
      Mechanisms of Reduced Maternal and Fetal Lopinavir Exposure in a Rat Model of Gestational Diabetes
      Gregory J. Anger and Micheline Piquette-Miller
      Drug Metabolism and Disposition October 2011, 39 (10) 1850-1859; DOI: https://doi.org/10.1124/dmd.111.040626
  3. Antoun, Joseph

    1. You have access
      CYP4F3B Expression Is Associated with Differentiation of HepaRG Human Hepatocytes and Unaffected by Fatty Acid Overload
      Stéphanie Madec, Virginie Cerec, Emmanuelle Plée-Gautier, Joseph Antoun, Denise Glaise, Jean-Pierre Salaun, Christiane Guguen-Guillouzo and Anne Corlu
      Drug Metabolism and Disposition October 2011, 39 (10) 1987-1996; DOI: https://doi.org/10.1124/dmd.110.036848
  4. Aoki, Katsuyuki

    1. You have access
      Pharmacokinetics of Daikenchuto, a Traditional Japanese Medicine (Kampo) after Single Oral Administration to Healthy Japanese Volunteers
      Masaya Munekage, Hiroyuki Kitagawa, Kengo Ichikawa, Junko Watanabe, Katsuyuki Aoki, Toru Kono and Kazuhiro Hanazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1784-1788; DOI: https://doi.org/10.1124/dmd.111.040097
  5. Asanuma, Kimie

    1. You have access
      Pharmacokinetic and Pharmacodynamic Modeling of the Effect of an Sodium-Glucose Cotransporter Inhibitor, Phlorizin, on Renal Glucose Transport in Rats
      Koji Yamaguchi, Motohiro Kato, Masayuki Suzuki, Kimie Asanuma, Yoshinori Aso, Sachiya Ikeda and Masaki Ishigai
      Drug Metabolism and Disposition October 2011, 39 (10) 1801-1807; DOI: https://doi.org/10.1124/dmd.111.040048
  6. Aso, Yoshinori

    1. You have access
      Pharmacokinetic and Pharmacodynamic Modeling of the Effect of an Sodium-Glucose Cotransporter Inhibitor, Phlorizin, on Renal Glucose Transport in Rats
      Koji Yamaguchi, Motohiro Kato, Masayuki Suzuki, Kimie Asanuma, Yoshinori Aso, Sachiya Ikeda and Masaki Ishigai
      Drug Metabolism and Disposition October 2011, 39 (10) 1801-1807; DOI: https://doi.org/10.1124/dmd.111.040048
  7. Awwad, Michel

    1. You have access
      How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
      Eugenia Kraynov, Steven W. Martin, Susan Hurst, Odette A. Fahmi, Martin Dowty, Carol Cronenberger, Cho-Ming Loi, Bing Kuang, Owen Fields, Scott Fountain, Michel Awwad and Diane Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1779-1783; DOI: https://doi.org/10.1124/dmd.111.040808

B

  1. Backman, Janne T.

    1. You have access
      Dose-Dependent Interaction between Gemfibrozil and Repaglinide in Humans: Strong Inhibition of CYP2C8 with Subtherapeutic Gemfibrozil Doses
      Johanna Honkalammi, Mikko Niemi, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition October 2011, 39 (10) 1977-1986; DOI: https://doi.org/10.1124/dmd.111.040931
  2. Baumgardner, Matthew

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  3. Bennett, Mark K.

    1. You have access
      Pharmacokinetics, Pharmacodynamics, Metabolism, Distribution, and Excretion of Carfilzomib in Rats
      Jinfu Yang, Zhengping Wang, Ying Fang, Jing Jiang, Frances Zhao, Hansen Wong, Mark K. Bennett, Christopher J. Molineaux and Christopher J. Kirk
      Drug Metabolism and Disposition October 2011, 39 (10) 1873-1882; DOI: https://doi.org/10.1124/dmd.111.039164
  4. Bergström, Moa Andresen

    1. You have access
      Bioactivation Pathways of the Cannabinoid Receptor 1 Antagonist Rimonabant
      Moa Andresen Bergström, Emre M. Isin, Neal Castagnoli and Claire E. Milne
      Drug Metabolism and Disposition October 2011, 39 (10) 1823-1832; DOI: https://doi.org/10.1124/dmd.111.039412
  5. Billheimer, D. Dean

    1. You have access
      Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease
      April D. Lake, Petr Novak, Craig D. Fisher, Jonathan P. Jackson, Rhiannon N. Hardwick, D. Dean Billheimer, Walter T. Klimecki and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2011, 39 (10) 1954-1960; DOI: https://doi.org/10.1124/dmd.111.040592
  6. Boggs, Jason

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  7. Bratton, Stacie M.

    1. You have access
      Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
      Krishna C. Chimalakonda, Stacie M. Bratton, Vi-Huyen Le, Kan Hui Yiew, Anna Dineva, Cindy L. Moran, Laura P. James, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2011, 39 (10) 1967-1976; DOI: https://doi.org/10.1124/dmd.111.040709
  8. Bui, Khanh H.

    1. You have access
      In Vitro and In Vivo Metabolism of a Selective δ-Opioid Receptor
      Jian Guo, Chungang Gu, Diansong Zhou, Charles S. Elmore, Khanh H. Bui and Scott W. Grimm
      Drug Metabolism and Disposition October 2011, 39 (10) 1883-1894; DOI: https://doi.org/10.1124/dmd.111.040980
  9. Burks, Scott R.

    1. You have access
      Clearance and Biodistribution of Liposomally Encapsulated Nitroxides: A Model for Targeted Delivery of Electron Paramagnetic Resonance Imaging Probes to Tumors
      Scott R. Burks, Eric A. Legenzov, Gerald M. Rosen and Joseph P. Y. Kao
      Drug Metabolism and Disposition October 2011, 39 (10) 1961-1966; DOI: https://doi.org/10.1124/dmd.111.039636

C

  1. Castagnoli, Neal

    1. You have access
      Bioactivation Pathways of the Cannabinoid Receptor 1 Antagonist Rimonabant
      Moa Andresen Bergström, Emre M. Isin, Neal Castagnoli and Claire E. Milne
      Drug Metabolism and Disposition October 2011, 39 (10) 1823-1832; DOI: https://doi.org/10.1124/dmd.111.039412
  2. Cerec, Virginie

    1. You have access
      CYP4F3B Expression Is Associated with Differentiation of HepaRG Human Hepatocytes and Unaffected by Fatty Acid Overload
      Stéphanie Madec, Virginie Cerec, Emmanuelle Plée-Gautier, Joseph Antoun, Denise Glaise, Jean-Pierre Salaun, Christiane Guguen-Guillouzo and Anne Corlu
      Drug Metabolism and Disposition October 2011, 39 (10) 1987-1996; DOI: https://doi.org/10.1124/dmd.110.036848
  3. Chen, Jianjun

    1. You have access
      Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability
      Chien-Ming Li, Jianjun Chen, Yan Lu, Ramesh Narayanan, Deanna N. Parke, Wei Li, Sunjoo Ahn, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition October 2011, 39 (10) 1833-1839; DOI: https://doi.org/10.1124/dmd.110.036616
  4. Chen, Leon

    1. You have access
      Distribution of KAI-9803, a Novel δ-Protein Kinase C Inhibitor, after Intravenous Administration to Rats
      Yoshihiro Miyaji, Sarah Walter, Leon Chen, Atsushi Kurihara, Tomoko Ishizuka, Motoko Saito, Kenji Kawai and Osamu Okazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1946-1953; DOI: https://doi.org/10.1124/dmd.111.040725
  5. Cherrington, Nathan J.

    1. You have access
      Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease
      April D. Lake, Petr Novak, Craig D. Fisher, Jonathan P. Jackson, Rhiannon N. Hardwick, D. Dean Billheimer, Walter T. Klimecki and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2011, 39 (10) 1954-1960; DOI: https://doi.org/10.1124/dmd.111.040592
  6. Chimalakonda, Krishna C.

    1. You have access
      Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
      Krishna C. Chimalakonda, Stacie M. Bratton, Vi-Huyen Le, Kan Hui Yiew, Anna Dineva, Cindy L. Moran, Laura P. James, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2011, 39 (10) 1967-1976; DOI: https://doi.org/10.1124/dmd.111.040709
  7. Coelho, Catarina

    1. You have access
      Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein Expression
      Martin Mahro, Catarina Coelho, José Trincão, David Rodrigues, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Maria João Romão and Silke Leimkühler
      Drug Metabolism and Disposition October 2011, 39 (10) 1939-1945; DOI: https://doi.org/10.1124/dmd.111.040873
  8. Coraggio, Melis

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  9. Corlu, Anne

    1. You have access
      CYP4F3B Expression Is Associated with Differentiation of HepaRG Human Hepatocytes and Unaffected by Fatty Acid Overload
      Stéphanie Madec, Virginie Cerec, Emmanuelle Plée-Gautier, Joseph Antoun, Denise Glaise, Jean-Pierre Salaun, Christiane Guguen-Guillouzo and Anne Corlu
      Drug Metabolism and Disposition October 2011, 39 (10) 1987-1996; DOI: https://doi.org/10.1124/dmd.110.036848
  10. Cronenberger, Carol

    1. You have access
      How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
      Eugenia Kraynov, Steven W. Martin, Susan Hurst, Odette A. Fahmi, Martin Dowty, Carol Cronenberger, Cho-Ming Loi, Bing Kuang, Owen Fields, Scott Fountain, Michel Awwad and Diane Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1779-1783; DOI: https://doi.org/10.1124/dmd.111.040808
  11. Currie, Kevin S.

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840

D

  1. Dalton, James T.

    1. You have access
      Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability
      Chien-Ming Li, Jianjun Chen, Yan Lu, Ramesh Narayanan, Deanna N. Parke, Wei Li, Sunjoo Ahn, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition October 2011, 39 (10) 1833-1839; DOI: https://doi.org/10.1124/dmd.110.036616
  2. Davis, John

    1. You have access
      Measurement of Binding of Basic Drugs to Acidic Phospholipids Using Surface Plasmon Resonance and Incorporation of the Data into Mechanistic Tissue Composition Equations to Predict Steady-State Volume of Distribution
      Helen Small, Iain Gardner, Hannah M. Jones, John Davis and Malcolm Rowland
      Drug Metabolism and Disposition October 2011, 39 (10) 1789-1793; DOI: https://doi.org/10.1124/dmd.111.040253
  3. Davis, John C.

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  4. Day, Jeffrey S.

    1. You have access
      Efflux Transport Is an Important Determinant of Ethinylestradiol Glucuronide and Ethinylestradiol Sulfate Pharmacokinetics
      Maciej J. Zamek-Gliszczynski, Jeffrey S. Day, Kathleen M. Hillgren and Diane L. Phillips
      Drug Metabolism and Disposition October 2011, 39 (10) 1794-1800; DOI: https://doi.org/10.1124/dmd.111.040162
  5. Deese, Alan

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  6. Dineva, Anna

    1. You have access
      Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
      Krishna C. Chimalakonda, Stacie M. Bratton, Vi-Huyen Le, Kan Hui Yiew, Anna Dineva, Cindy L. Moran, Laura P. James, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2011, 39 (10) 1967-1976; DOI: https://doi.org/10.1124/dmd.111.040709
  7. Dowty, Martin

    1. You have access
      How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
      Eugenia Kraynov, Steven W. Martin, Susan Hurst, Odette A. Fahmi, Martin Dowty, Carol Cronenberger, Cho-Ming Loi, Bing Kuang, Owen Fields, Scott Fountain, Michel Awwad and Diane Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1779-1783; DOI: https://doi.org/10.1124/dmd.111.040808

E

  1. Elmore, Charles S.

    1. You have access
      In Vitro and In Vivo Metabolism of a Selective δ-Opioid Receptor
      Jian Guo, Chungang Gu, Diansong Zhou, Charles S. Elmore, Khanh H. Bui and Scott W. Grimm
      Drug Metabolism and Disposition October 2011, 39 (10) 1883-1894; DOI: https://doi.org/10.1124/dmd.111.040980

F

  1. Fahmi, Odette A.

    1. You have access
      How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
      Eugenia Kraynov, Steven W. Martin, Susan Hurst, Odette A. Fahmi, Martin Dowty, Carol Cronenberger, Cho-Ming Loi, Bing Kuang, Owen Fields, Scott Fountain, Michel Awwad and Diane Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1779-1783; DOI: https://doi.org/10.1124/dmd.111.040808
  2. Fang, Ying

    1. You have access
      Pharmacokinetics, Pharmacodynamics, Metabolism, Distribution, and Excretion of Carfilzomib in Rats
      Jinfu Yang, Zhengping Wang, Ying Fang, Jing Jiang, Frances Zhao, Hansen Wong, Mark K. Bennett, Christopher J. Molineaux and Christopher J. Kirk
      Drug Metabolism and Disposition October 2011, 39 (10) 1873-1882; DOI: https://doi.org/10.1124/dmd.111.039164
  3. Fields, Owen

    1. You have access
      How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
      Eugenia Kraynov, Steven W. Martin, Susan Hurst, Odette A. Fahmi, Martin Dowty, Carol Cronenberger, Cho-Ming Loi, Bing Kuang, Owen Fields, Scott Fountain, Michel Awwad and Diane Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1779-1783; DOI: https://doi.org/10.1124/dmd.111.040808
  4. Fisher, Craig D.

    1. You have access
      Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease
      April D. Lake, Petr Novak, Craig D. Fisher, Jonathan P. Jackson, Rhiannon N. Hardwick, D. Dean Billheimer, Walter T. Klimecki and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2011, 39 (10) 1954-1960; DOI: https://doi.org/10.1124/dmd.111.040592
  5. Fountain, Scott

    1. You have access
      How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
      Eugenia Kraynov, Steven W. Martin, Susan Hurst, Odette A. Fahmi, Martin Dowty, Carol Cronenberger, Cho-Ming Loi, Bing Kuang, Owen Fields, Scott Fountain, Michel Awwad and Diane Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1779-1783; DOI: https://doi.org/10.1124/dmd.111.040808

G

  1. Galetin, Aleksandra

    1. You have access
      Predictive Utility of In Vitro Rifampin Induction Data Generated in Fresh and Cryopreserved Human Hepatocytes, Fa2N-4, and HepaRG Cells
      Ian E. Templeton, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition October 2011, 39 (10) 1921-1929; DOI: https://doi.org/10.1124/dmd.111.040824
    2. You have access
      Kinetic Characterization of Rat Hepatic Uptake of 16 Actively Transported Drugs
      Yoshiyuki Yabe, Aleksandra Galetin and J. Brian Houston
      Drug Metabolism and Disposition October 2011, 39 (10) 1808-1814; DOI: https://doi.org/10.1124/dmd.111.040477
  2. Gao, Song

    1. You have access
      Enhancement of Oral Bioavailability of 20(S)-Ginsenoside Rh2 through Improved Understanding of Its Absorption and Efflux Mechanisms
      Zhen Yang, Song Gao, Jingrong Wang, Taijun Yin, Yang Teng, Baojian Wu, Ming You, Zhihong Jiang and Ming Hu
      Drug Metabolism and Disposition October 2011, 39 (10) 1866-1872; DOI: https://doi.org/10.1124/dmd.111.040006
  3. Garattini, Enrico

    1. You have access
      Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein Expression
      Martin Mahro, Catarina Coelho, José Trincão, David Rodrigues, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Maria João Romão and Silke Leimkühler
      Drug Metabolism and Disposition October 2011, 39 (10) 1939-1945; DOI: https://doi.org/10.1124/dmd.111.040873
  4. Gardiner, Philip

    1. You have access
      The Impact of Hepatic Uptake on the Pharmacokinetics of Organic Anions
      Philip Gardiner and Stuart W. Paine
      Drug Metabolism and Disposition October 2011, 39 (10) 1930-1938; DOI: https://doi.org/10.1124/dmd.111.039842
  5. Gardner, Iain

    1. You have access
      Measurement of Binding of Basic Drugs to Acidic Phospholipids Using Surface Plasmon Resonance and Incorporation of the Data into Mechanistic Tissue Composition Equations to Predict Steady-State Volume of Distribution
      Helen Small, Iain Gardner, Hannah M. Jones, John Davis and Malcolm Rowland
      Drug Metabolism and Disposition October 2011, 39 (10) 1789-1793; DOI: https://doi.org/10.1124/dmd.111.040253
  6. Glaise, Denise

    1. You have access
      CYP4F3B Expression Is Associated with Differentiation of HepaRG Human Hepatocytes and Unaffected by Fatty Acid Overload
      Stéphanie Madec, Virginie Cerec, Emmanuelle Plée-Gautier, Joseph Antoun, Denise Glaise, Jean-Pierre Salaun, Christiane Guguen-Guillouzo and Anne Corlu
      Drug Metabolism and Disposition October 2011, 39 (10) 1987-1996; DOI: https://doi.org/10.1124/dmd.110.036848
  7. Gong, Ping

    1. You have access
      Thioacetamide Intoxication Triggers Transcriptional Up-Regulation but Enzyme Inactivation of UDP-Glucuronosyltransferases
      Haiping Hao, Lifang Zhang, Shan Jiang, Shiqing Sun, Ping Gong, Yuan Xie, Xueyan Zhou and Guangji Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1815-1822; DOI: https://doi.org/10.1124/dmd.111.039172
  8. Gopaul, Sashi

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  9. Grimm, Scott W.

    1. You have access
      In Vitro and In Vivo Metabolism of a Selective δ-Opioid Receptor
      Jian Guo, Chungang Gu, Diansong Zhou, Charles S. Elmore, Khanh H. Bui and Scott W. Grimm
      Drug Metabolism and Disposition October 2011, 39 (10) 1883-1894; DOI: https://doi.org/10.1124/dmd.111.040980
  10. Gu, Chungang

    1. You have access
      In Vitro and In Vivo Metabolism of a Selective δ-Opioid Receptor
      Jian Guo, Chungang Gu, Diansong Zhou, Charles S. Elmore, Khanh H. Bui and Scott W. Grimm
      Drug Metabolism and Disposition October 2011, 39 (10) 1883-1894; DOI: https://doi.org/10.1124/dmd.111.040980
  11. Guguen-Guillouzo, Christiane

    1. You have access
      CYP4F3B Expression Is Associated with Differentiation of HepaRG Human Hepatocytes and Unaffected by Fatty Acid Overload
      Stéphanie Madec, Virginie Cerec, Emmanuelle Plée-Gautier, Joseph Antoun, Denise Glaise, Jean-Pierre Salaun, Christiane Guguen-Guillouzo and Anne Corlu
      Drug Metabolism and Disposition October 2011, 39 (10) 1987-1996; DOI: https://doi.org/10.1124/dmd.110.036848
  12. Guo, Jian

    1. You have access
      In Vitro and In Vivo Metabolism of a Selective δ-Opioid Receptor
      Jian Guo, Chungang Gu, Diansong Zhou, Charles S. Elmore, Khanh H. Bui and Scott W. Grimm
      Drug Metabolism and Disposition October 2011, 39 (10) 1883-1894; DOI: https://doi.org/10.1124/dmd.111.040980

H

  1. Halladay, Jason S.

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  2. Hanazaki, Kazuhiro

    1. You have access
      Pharmacokinetics of Daikenchuto, a Traditional Japanese Medicine (Kampo) after Single Oral Administration to Healthy Japanese Volunteers
      Masaya Munekage, Hiroyuki Kitagawa, Kengo Ichikawa, Junko Watanabe, Katsuyuki Aoki, Toru Kono and Kazuhiro Hanazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1784-1788; DOI: https://doi.org/10.1124/dmd.111.040097
  3. Hao, Haiping

    1. You have access
      Thioacetamide Intoxication Triggers Transcriptional Up-Regulation but Enzyme Inactivation of UDP-Glucuronosyltransferases
      Haiping Hao, Lifang Zhang, Shan Jiang, Shiqing Sun, Ping Gong, Yuan Xie, Xueyan Zhou and Guangji Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1815-1822; DOI: https://doi.org/10.1124/dmd.111.039172
  4. Hardwick, Rhiannon N.

    1. You have access
      Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease
      April D. Lake, Petr Novak, Craig D. Fisher, Jonathan P. Jackson, Rhiannon N. Hardwick, D. Dean Billheimer, Walter T. Klimecki and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2011, 39 (10) 1954-1960; DOI: https://doi.org/10.1124/dmd.111.040592
  5. Hildebrandt, Peter

    1. You have access
      Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein Expression
      Martin Mahro, Catarina Coelho, José Trincão, David Rodrigues, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Maria João Romão and Silke Leimkühler
      Drug Metabolism and Disposition October 2011, 39 (10) 1939-1945; DOI: https://doi.org/10.1124/dmd.111.040873
  6. Hillgren, Kathleen M.

    1. You have access
      Efflux Transport Is an Important Determinant of Ethinylestradiol Glucuronide and Ethinylestradiol Sulfate Pharmacokinetics
      Maciej J. Zamek-Gliszczynski, Jeffrey S. Day, Kathleen M. Hillgren and Diane L. Phillips
      Drug Metabolism and Disposition October 2011, 39 (10) 1794-1800; DOI: https://doi.org/10.1124/dmd.111.040162
  7. Hirasawa, Noriyasu

    1. You have access
      Functional Characterization of CYP2B6 Allelic Variants in Demethylation of Antimalarial Artemether
      Masashi Honda, Yuka Muroi, Yuichiro Tamaki, Daisuke Saigusa, Naoto Suzuki, Yoshihisa Tomioka, Yoichi Matsubara, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition October 2011, 39 (10) 1860-1865; DOI: https://doi.org/10.1124/dmd.111.040352
  8. Hiratsuka, Masahiro

    1. You have access
      Functional Characterization of CYP2B6 Allelic Variants in Demethylation of Antimalarial Artemether
      Masashi Honda, Yuka Muroi, Yuichiro Tamaki, Daisuke Saigusa, Naoto Suzuki, Yoshihisa Tomioka, Yoichi Matsubara, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition October 2011, 39 (10) 1860-1865; DOI: https://doi.org/10.1124/dmd.111.040352
  9. Honda, Masashi

    1. You have access
      Functional Characterization of CYP2B6 Allelic Variants in Demethylation of Antimalarial Artemether
      Masashi Honda, Yuka Muroi, Yuichiro Tamaki, Daisuke Saigusa, Naoto Suzuki, Yoshihisa Tomioka, Yoichi Matsubara, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition October 2011, 39 (10) 1860-1865; DOI: https://doi.org/10.1124/dmd.111.040352
  10. Hong, Lan

    1. You have access
      Brain Regional Pharmacokinetics of p-Aminosalicylic Acid and Its N-Acetylated Metabolite: Effectiveness in Chelating Brain Manganese
      Lan Hong, Wendy Jiang, Hao Pan, Yueming Jiang, Su Zeng and Wei Zheng
      Drug Metabolism and Disposition October 2011, 39 (10) 1904-1909; DOI: https://doi.org/10.1124/dmd.111.040915
  11. Honkalammi, Johanna

    1. You have access
      Dose-Dependent Interaction between Gemfibrozil and Repaglinide in Humans: Strong Inhibition of CYP2C8 with Subtherapeutic Gemfibrozil Doses
      Johanna Honkalammi, Mikko Niemi, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition October 2011, 39 (10) 1977-1986; DOI: https://doi.org/10.1124/dmd.111.040931
  12. Hop, Cornelis E. C. A.

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  13. Houston, J. Brian

    1. You have access
      Predictive Utility of In Vitro Rifampin Induction Data Generated in Fresh and Cryopreserved Human Hepatocytes, Fa2N-4, and HepaRG Cells
      Ian E. Templeton, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition October 2011, 39 (10) 1921-1929; DOI: https://doi.org/10.1124/dmd.111.040824
    2. You have access
      Kinetic Characterization of Rat Hepatic Uptake of 16 Actively Transported Drugs
      Yoshiyuki Yabe, Aleksandra Galetin and J. Brian Houston
      Drug Metabolism and Disposition October 2011, 39 (10) 1808-1814; DOI: https://doi.org/10.1124/dmd.111.040477
  14. Hu, Ming

    1. You have access
      Enhancement of Oral Bioavailability of 20(S)-Ginsenoside Rh2 through Improved Understanding of Its Absorption and Efflux Mechanisms
      Zhen Yang, Song Gao, Jingrong Wang, Taijun Yin, Yang Teng, Baojian Wu, Ming You, Zhihong Jiang and Ming Hu
      Drug Metabolism and Disposition October 2011, 39 (10) 1866-1872; DOI: https://doi.org/10.1124/dmd.111.040006
  15. Hunt, C. Anthony

    1. You have access
      Enabling Clearance Predictions to Emerge from In Silico Actions of Quasi-Autonomous Hepatocyte Components
      Shahab Sheikh-Bahaei and C. Anthony Hunt
      Drug Metabolism and Disposition October 2011, 39 (10) 1910-1920; DOI: https://doi.org/10.1124/dmd.111.038703
  16. Hurst, Susan

    1. You have access
      How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
      Eugenia Kraynov, Steven W. Martin, Susan Hurst, Odette A. Fahmi, Martin Dowty, Carol Cronenberger, Cho-Ming Loi, Bing Kuang, Owen Fields, Scott Fountain, Michel Awwad and Diane Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1779-1783; DOI: https://doi.org/10.1124/dmd.111.040808

I

  1. Ichikawa, Kengo

    1. You have access
      Pharmacokinetics of Daikenchuto, a Traditional Japanese Medicine (Kampo) after Single Oral Administration to Healthy Japanese Volunteers
      Masaya Munekage, Hiroyuki Kitagawa, Kengo Ichikawa, Junko Watanabe, Katsuyuki Aoki, Toru Kono and Kazuhiro Hanazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1784-1788; DOI: https://doi.org/10.1124/dmd.111.040097
  2. Ikeda, Sachiya

    1. You have access
      Pharmacokinetic and Pharmacodynamic Modeling of the Effect of an Sodium-Glucose Cotransporter Inhibitor, Phlorizin, on Renal Glucose Transport in Rats
      Koji Yamaguchi, Motohiro Kato, Masayuki Suzuki, Kimie Asanuma, Yoshinori Aso, Sachiya Ikeda and Masaki Ishigai
      Drug Metabolism and Disposition October 2011, 39 (10) 1801-1807; DOI: https://doi.org/10.1124/dmd.111.040048
  3. Ishigai, Masaki

    1. You have access
      Pharmacokinetic and Pharmacodynamic Modeling of the Effect of an Sodium-Glucose Cotransporter Inhibitor, Phlorizin, on Renal Glucose Transport in Rats
      Koji Yamaguchi, Motohiro Kato, Masayuki Suzuki, Kimie Asanuma, Yoshinori Aso, Sachiya Ikeda and Masaki Ishigai
      Drug Metabolism and Disposition October 2011, 39 (10) 1801-1807; DOI: https://doi.org/10.1124/dmd.111.040048
  4. Ishizuka, Tomoko

    1. You have access
      Distribution of KAI-9803, a Novel δ-Protein Kinase C Inhibitor, after Intravenous Administration to Rats
      Yoshihiro Miyaji, Sarah Walter, Leon Chen, Atsushi Kurihara, Tomoko Ishizuka, Motoko Saito, Kenji Kawai and Osamu Okazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1946-1953; DOI: https://doi.org/10.1124/dmd.111.040725
  5. Isin, Emre M.

    1. You have access
      Bioactivation Pathways of the Cannabinoid Receptor 1 Antagonist Rimonabant
      Moa Andresen Bergström, Emre M. Isin, Neal Castagnoli and Claire E. Milne
      Drug Metabolism and Disposition October 2011, 39 (10) 1823-1832; DOI: https://doi.org/10.1124/dmd.111.039412

J

  1. Jackson, Jonathan P.

    1. You have access
      Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease
      April D. Lake, Petr Novak, Craig D. Fisher, Jonathan P. Jackson, Rhiannon N. Hardwick, D. Dean Billheimer, Walter T. Klimecki and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2011, 39 (10) 1954-1960; DOI: https://doi.org/10.1124/dmd.111.040592
  2. James, Laura P.

    1. You have access
      Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
      Krishna C. Chimalakonda, Stacie M. Bratton, Vi-Huyen Le, Kan Hui Yiew, Anna Dineva, Cindy L. Moran, Laura P. James, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2011, 39 (10) 1967-1976; DOI: https://doi.org/10.1124/dmd.111.040709
  3. Jiang, Jing

    1. You have access
      Pharmacokinetics, Pharmacodynamics, Metabolism, Distribution, and Excretion of Carfilzomib in Rats
      Jinfu Yang, Zhengping Wang, Ying Fang, Jing Jiang, Frances Zhao, Hansen Wong, Mark K. Bennett, Christopher J. Molineaux and Christopher J. Kirk
      Drug Metabolism and Disposition October 2011, 39 (10) 1873-1882; DOI: https://doi.org/10.1124/dmd.111.039164
  4. Jiang, Shan

    1. You have access
      Thioacetamide Intoxication Triggers Transcriptional Up-Regulation but Enzyme Inactivation of UDP-Glucuronosyltransferases
      Haiping Hao, Lifang Zhang, Shan Jiang, Shiqing Sun, Ping Gong, Yuan Xie, Xueyan Zhou and Guangji Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1815-1822; DOI: https://doi.org/10.1124/dmd.111.039172
  5. Jiang, Wendy

    1. You have access
      Brain Regional Pharmacokinetics of p-Aminosalicylic Acid and Its N-Acetylated Metabolite: Effectiveness in Chelating Brain Manganese
      Lan Hong, Wendy Jiang, Hao Pan, Yueming Jiang, Su Zeng and Wei Zheng
      Drug Metabolism and Disposition October 2011, 39 (10) 1904-1909; DOI: https://doi.org/10.1124/dmd.111.040915
  6. Jiang, Yueming

    1. You have access
      Brain Regional Pharmacokinetics of p-Aminosalicylic Acid and Its N-Acetylated Metabolite: Effectiveness in Chelating Brain Manganese
      Lan Hong, Wendy Jiang, Hao Pan, Yueming Jiang, Su Zeng and Wei Zheng
      Drug Metabolism and Disposition October 2011, 39 (10) 1904-1909; DOI: https://doi.org/10.1124/dmd.111.040915
  7. Jiang, Zhihong

    1. You have access
      Enhancement of Oral Bioavailability of 20(S)-Ginsenoside Rh2 through Improved Understanding of Its Absorption and Efflux Mechanisms
      Zhen Yang, Song Gao, Jingrong Wang, Taijun Yin, Yang Teng, Baojian Wu, Ming You, Zhihong Jiang and Ming Hu
      Drug Metabolism and Disposition October 2011, 39 (10) 1866-1872; DOI: https://doi.org/10.1124/dmd.111.040006
  8. Jones, Hannah M.

    1. You have access
      Measurement of Binding of Basic Drugs to Acidic Phospholipids Using Surface Plasmon Resonance and Incorporation of the Data into Mechanistic Tissue Composition Equations to Predict Steady-State Volume of Distribution
      Helen Small, Iain Gardner, Hannah M. Jones, John Davis and Malcolm Rowland
      Drug Metabolism and Disposition October 2011, 39 (10) 1789-1793; DOI: https://doi.org/10.1124/dmd.111.040253

K

  1. Kao, Joseph P. Y.

    1. You have access
      Clearance and Biodistribution of Liposomally Encapsulated Nitroxides: A Model for Targeted Delivery of Electron Paramagnetic Resonance Imaging Probes to Tumors
      Scott R. Burks, Eric A. Legenzov, Gerald M. Rosen and Joseph P. Y. Kao
      Drug Metabolism and Disposition October 2011, 39 (10) 1961-1966; DOI: https://doi.org/10.1124/dmd.111.039636
  2. Kato, Motohiro

    1. You have access
      Pharmacokinetic and Pharmacodynamic Modeling of the Effect of an Sodium-Glucose Cotransporter Inhibitor, Phlorizin, on Renal Glucose Transport in Rats
      Koji Yamaguchi, Motohiro Kato, Masayuki Suzuki, Kimie Asanuma, Yoshinori Aso, Sachiya Ikeda and Masaki Ishigai
      Drug Metabolism and Disposition October 2011, 39 (10) 1801-1807; DOI: https://doi.org/10.1124/dmd.111.040048
  3. Kawai, Kenji

    1. You have access
      Distribution of KAI-9803, a Novel δ-Protein Kinase C Inhibitor, after Intravenous Administration to Rats
      Yoshihiro Miyaji, Sarah Walter, Leon Chen, Atsushi Kurihara, Tomoko Ishizuka, Motoko Saito, Kenji Kawai and Osamu Okazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1946-1953; DOI: https://doi.org/10.1124/dmd.111.040725
  4. Khojasteh, S. Cyrus

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  5. Kirk, Christopher J.

    1. You have access
      Pharmacokinetics, Pharmacodynamics, Metabolism, Distribution, and Excretion of Carfilzomib in Rats
      Jinfu Yang, Zhengping Wang, Ying Fang, Jing Jiang, Frances Zhao, Hansen Wong, Mark K. Bennett, Christopher J. Molineaux and Christopher J. Kirk
      Drug Metabolism and Disposition October 2011, 39 (10) 1873-1882; DOI: https://doi.org/10.1124/dmd.111.039164
  6. Kitagawa, Hiroyuki

    1. You have access
      Pharmacokinetics of Daikenchuto, a Traditional Japanese Medicine (Kampo) after Single Oral Administration to Healthy Japanese Volunteers
      Masaya Munekage, Hiroyuki Kitagawa, Kengo Ichikawa, Junko Watanabe, Katsuyuki Aoki, Toru Kono and Kazuhiro Hanazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1784-1788; DOI: https://doi.org/10.1124/dmd.111.040097
  7. Klimecki, Walter T.

    1. You have access
      Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease
      April D. Lake, Petr Novak, Craig D. Fisher, Jonathan P. Jackson, Rhiannon N. Hardwick, D. Dean Billheimer, Walter T. Klimecki and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2011, 39 (10) 1954-1960; DOI: https://doi.org/10.1124/dmd.111.040592
  8. Koechling, Wolfgang

    1. You have access
      Metabolite Profiles of Degarelix, a New Gonadotropin-Releasing Hormone Receptor Antagonist, in Rat, Dog, and Monkey
      Anders Sonesson, Wolfgang Koechling, Jacek Stalewski, László B. Tankó and Birgitte Buur Rasmussen
      Drug Metabolism and Disposition October 2011, 39 (10) 1895-1903; DOI: https://doi.org/10.1124/dmd.111.039883
  9. Kono, Toru

    1. You have access
      Pharmacokinetics of Daikenchuto, a Traditional Japanese Medicine (Kampo) after Single Oral Administration to Healthy Japanese Volunteers
      Masaya Munekage, Hiroyuki Kitagawa, Kengo Ichikawa, Junko Watanabe, Katsuyuki Aoki, Toru Kono and Kazuhiro Hanazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1784-1788; DOI: https://doi.org/10.1124/dmd.111.040097
  10. Kraynov, Eugenia

    1. You have access
      How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
      Eugenia Kraynov, Steven W. Martin, Susan Hurst, Odette A. Fahmi, Martin Dowty, Carol Cronenberger, Cho-Ming Loi, Bing Kuang, Owen Fields, Scott Fountain, Michel Awwad and Diane Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1779-1783; DOI: https://doi.org/10.1124/dmd.111.040808
  11. Kuang, Bing

    1. You have access
      How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
      Eugenia Kraynov, Steven W. Martin, Susan Hurst, Odette A. Fahmi, Martin Dowty, Carol Cronenberger, Cho-Ming Loi, Bing Kuang, Owen Fields, Scott Fountain, Michel Awwad and Diane Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1779-1783; DOI: https://doi.org/10.1124/dmd.111.040808
  12. Kuebler, Peter

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  13. Kurihara, Atsushi

    1. You have access
      Distribution of KAI-9803, a Novel δ-Protein Kinase C Inhibitor, after Intravenous Administration to Rats
      Yoshihiro Miyaji, Sarah Walter, Leon Chen, Atsushi Kurihara, Tomoko Ishizuka, Motoko Saito, Kenji Kawai and Osamu Okazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1946-1953; DOI: https://doi.org/10.1124/dmd.111.040725

L

  1. La, Hank

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  2. Lake, April D.

    1. You have access
      Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease
      April D. Lake, Petr Novak, Craig D. Fisher, Jonathan P. Jackson, Rhiannon N. Hardwick, D. Dean Billheimer, Walter T. Klimecki and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2011, 39 (10) 1954-1960; DOI: https://doi.org/10.1124/dmd.111.040592
  3. Le, Hoa

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  4. Le, Vi-Huyen

    1. You have access
      Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
      Krishna C. Chimalakonda, Stacie M. Bratton, Vi-Huyen Le, Kan Hui Yiew, Anna Dineva, Cindy L. Moran, Laura P. James, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2011, 39 (10) 1967-1976; DOI: https://doi.org/10.1124/dmd.111.040709
  5. Legenzov, Eric A.

    1. You have access
      Clearance and Biodistribution of Liposomally Encapsulated Nitroxides: A Model for Targeted Delivery of Electron Paramagnetic Resonance Imaging Probes to Tumors
      Scott R. Burks, Eric A. Legenzov, Gerald M. Rosen and Joseph P. Y. Kao
      Drug Metabolism and Disposition October 2011, 39 (10) 1961-1966; DOI: https://doi.org/10.1124/dmd.111.039636
  6. Leimkühler, Silke

    1. You have access
      Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein Expression
      Martin Mahro, Catarina Coelho, José Trincão, David Rodrigues, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Maria João Romão and Silke Leimkühler
      Drug Metabolism and Disposition October 2011, 39 (10) 1939-1945; DOI: https://doi.org/10.1124/dmd.111.040873
  7. Lendzian, Friedhelm

    1. You have access
      Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein Expression
      Martin Mahro, Catarina Coelho, José Trincão, David Rodrigues, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Maria João Romão and Silke Leimkühler
      Drug Metabolism and Disposition October 2011, 39 (10) 1939-1945; DOI: https://doi.org/10.1124/dmd.111.040873
  8. Li, Chien-Ming

    1. You have access
      Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability
      Chien-Ming Li, Jianjun Chen, Yan Lu, Ramesh Narayanan, Deanna N. Parke, Wei Li, Sunjoo Ahn, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition October 2011, 39 (10) 1833-1839; DOI: https://doi.org/10.1124/dmd.110.036616
  9. Li, Wei

    1. You have access
      Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability
      Chien-Ming Li, Jianjun Chen, Yan Lu, Ramesh Narayanan, Deanna N. Parke, Wei Li, Sunjoo Ahn, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition October 2011, 39 (10) 1833-1839; DOI: https://doi.org/10.1124/dmd.110.036616
  10. Liao, X. Charlene

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  11. Liu, Lichuan

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  12. Loi, Cho-Ming

    1. You have access
      How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
      Eugenia Kraynov, Steven W. Martin, Susan Hurst, Odette A. Fahmi, Martin Dowty, Carol Cronenberger, Cho-Ming Loi, Bing Kuang, Owen Fields, Scott Fountain, Michel Awwad and Diane Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1779-1783; DOI: https://doi.org/10.1124/dmd.111.040808
  13. Lu, Yan

    1. You have access
      Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability
      Chien-Ming Li, Jianjun Chen, Yan Lu, Ramesh Narayanan, Deanna N. Parke, Wei Li, Sunjoo Ahn, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition October 2011, 39 (10) 1833-1839; DOI: https://doi.org/10.1124/dmd.110.036616
  14. Lubach, Joseph W.

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840

M

  1. Madec, Stéphanie

    1. You have access
      CYP4F3B Expression Is Associated with Differentiation of HepaRG Human Hepatocytes and Unaffected by Fatty Acid Overload
      Stéphanie Madec, Virginie Cerec, Emmanuelle Plée-Gautier, Joseph Antoun, Denise Glaise, Jean-Pierre Salaun, Christiane Guguen-Guillouzo and Anne Corlu
      Drug Metabolism and Disposition October 2011, 39 (10) 1987-1996; DOI: https://doi.org/10.1124/dmd.110.036848
  2. Mahro, Martin

    1. You have access
      Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein Expression
      Martin Mahro, Catarina Coelho, José Trincão, David Rodrigues, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Maria João Romão and Silke Leimkühler
      Drug Metabolism and Disposition October 2011, 39 (10) 1939-1945; DOI: https://doi.org/10.1124/dmd.111.040873
  3. Martin, Steven W.

    1. You have access
      How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
      Eugenia Kraynov, Steven W. Martin, Susan Hurst, Odette A. Fahmi, Martin Dowty, Carol Cronenberger, Cho-Ming Loi, Bing Kuang, Owen Fields, Scott Fountain, Michel Awwad and Diane Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1779-1783; DOI: https://doi.org/10.1124/dmd.111.040808
  4. Matsubara, Yoichi

    1. You have access
      Functional Characterization of CYP2B6 Allelic Variants in Demethylation of Antimalarial Artemether
      Masashi Honda, Yuka Muroi, Yuichiro Tamaki, Daisuke Saigusa, Naoto Suzuki, Yoshihisa Tomioka, Yoichi Matsubara, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition October 2011, 39 (10) 1860-1865; DOI: https://doi.org/10.1124/dmd.111.040352
  5. Miller, Duane D.

    1. You have access
      Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability
      Chien-Ming Li, Jianjun Chen, Yan Lu, Ramesh Narayanan, Deanna N. Parke, Wei Li, Sunjoo Ahn, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition October 2011, 39 (10) 1833-1839; DOI: https://doi.org/10.1124/dmd.110.036616
  6. Milne, Claire E.

    1. You have access
      Bioactivation Pathways of the Cannabinoid Receptor 1 Antagonist Rimonabant
      Moa Andresen Bergström, Emre M. Isin, Neal Castagnoli and Claire E. Milne
      Drug Metabolism and Disposition October 2011, 39 (10) 1823-1832; DOI: https://doi.org/10.1124/dmd.111.039412
  7. Miyaji, Yoshihiro

    1. You have access
      Distribution of KAI-9803, a Novel δ-Protein Kinase C Inhibitor, after Intravenous Administration to Rats
      Yoshihiro Miyaji, Sarah Walter, Leon Chen, Atsushi Kurihara, Tomoko Ishizuka, Motoko Saito, Kenji Kawai and Osamu Okazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1946-1953; DOI: https://doi.org/10.1124/dmd.111.040725
  8. Molineaux, Christopher J.

    1. You have access
      Pharmacokinetics, Pharmacodynamics, Metabolism, Distribution, and Excretion of Carfilzomib in Rats
      Jinfu Yang, Zhengping Wang, Ying Fang, Jing Jiang, Frances Zhao, Hansen Wong, Mark K. Bennett, Christopher J. Molineaux and Christopher J. Kirk
      Drug Metabolism and Disposition October 2011, 39 (10) 1873-1882; DOI: https://doi.org/10.1124/dmd.111.039164
  9. Moran, Cindy L.

    1. You have access
      Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
      Krishna C. Chimalakonda, Stacie M. Bratton, Vi-Huyen Le, Kan Hui Yiew, Anna Dineva, Cindy L. Moran, Laura P. James, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2011, 39 (10) 1967-1976; DOI: https://doi.org/10.1124/dmd.111.040709
  10. Moran, Jeffery H.

    1. You have access
      Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
      Krishna C. Chimalakonda, Stacie M. Bratton, Vi-Huyen Le, Kan Hui Yiew, Anna Dineva, Cindy L. Moran, Laura P. James, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2011, 39 (10) 1967-1976; DOI: https://doi.org/10.1124/dmd.111.040709
  11. Munekage, Masaya

    1. You have access
      Pharmacokinetics of Daikenchuto, a Traditional Japanese Medicine (Kampo) after Single Oral Administration to Healthy Japanese Volunteers
      Masaya Munekage, Hiroyuki Kitagawa, Kengo Ichikawa, Junko Watanabe, Katsuyuki Aoki, Toru Kono and Kazuhiro Hanazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1784-1788; DOI: https://doi.org/10.1124/dmd.111.040097
  12. Muroi, Yuka

    1. You have access
      Functional Characterization of CYP2B6 Allelic Variants in Demethylation of Antimalarial Artemether
      Masashi Honda, Yuka Muroi, Yuichiro Tamaki, Daisuke Saigusa, Naoto Suzuki, Yoshihisa Tomioka, Yoichi Matsubara, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition October 2011, 39 (10) 1860-1865; DOI: https://doi.org/10.1124/dmd.111.040352

N

  1. Narayanan, Ramesh

    1. You have access
      Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability
      Chien-Ming Li, Jianjun Chen, Yan Lu, Ramesh Narayanan, Deanna N. Parke, Wei Li, Sunjoo Ahn, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition October 2011, 39 (10) 1833-1839; DOI: https://doi.org/10.1124/dmd.110.036616
  2. Neuvonen, Pertti J.

    1. You have access
      Dose-Dependent Interaction between Gemfibrozil and Repaglinide in Humans: Strong Inhibition of CYP2C8 with Subtherapeutic Gemfibrozil Doses
      Johanna Honkalammi, Mikko Niemi, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition October 2011, 39 (10) 1977-1986; DOI: https://doi.org/10.1124/dmd.111.040931
  3. Niemi, Mikko

    1. You have access
      Dose-Dependent Interaction between Gemfibrozil and Repaglinide in Humans: Strong Inhibition of CYP2C8 with Subtherapeutic Gemfibrozil Doses
      Johanna Honkalammi, Mikko Niemi, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition October 2011, 39 (10) 1977-1986; DOI: https://doi.org/10.1124/dmd.111.040931
  4. Novak, Petr

    1. You have access
      Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease
      April D. Lake, Petr Novak, Craig D. Fisher, Jonathan P. Jackson, Rhiannon N. Hardwick, D. Dean Billheimer, Walter T. Klimecki and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2011, 39 (10) 1954-1960; DOI: https://doi.org/10.1124/dmd.111.040592

O

  1. Oda, Akifumi

    1. You have access
      Functional Characterization of CYP2B6 Allelic Variants in Demethylation of Antimalarial Artemether
      Masashi Honda, Yuka Muroi, Yuichiro Tamaki, Daisuke Saigusa, Naoto Suzuki, Yoshihisa Tomioka, Yoichi Matsubara, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition October 2011, 39 (10) 1860-1865; DOI: https://doi.org/10.1124/dmd.111.040352
  2. Okazaki, Osamu

    1. You have access
      Distribution of KAI-9803, a Novel δ-Protein Kinase C Inhibitor, after Intravenous Administration to Rats
      Yoshihiro Miyaji, Sarah Walter, Leon Chen, Atsushi Kurihara, Tomoko Ishizuka, Motoko Saito, Kenji Kawai and Osamu Okazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1946-1953; DOI: https://doi.org/10.1124/dmd.111.040725

P

  1. Paine, Stuart W.

    1. You have access
      The Impact of Hepatic Uptake on the Pharmacokinetics of Organic Anions
      Philip Gardiner and Stuart W. Paine
      Drug Metabolism and Disposition October 2011, 39 (10) 1930-1938; DOI: https://doi.org/10.1124/dmd.111.039842
  2. Pan, Hao

    1. You have access
      Brain Regional Pharmacokinetics of p-Aminosalicylic Acid and Its N-Acetylated Metabolite: Effectiveness in Chelating Brain Manganese
      Lan Hong, Wendy Jiang, Hao Pan, Yueming Jiang, Su Zeng and Wei Zheng
      Drug Metabolism and Disposition October 2011, 39 (10) 1904-1909; DOI: https://doi.org/10.1124/dmd.111.040915
  3. Parke, Deanna N.

    1. You have access
      Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability
      Chien-Ming Li, Jianjun Chen, Yan Lu, Ramesh Narayanan, Deanna N. Parke, Wei Li, Sunjoo Ahn, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition October 2011, 39 (10) 1833-1839; DOI: https://doi.org/10.1124/dmd.110.036616
  4. Phillips, Diane L.

    1. You have access
      Efflux Transport Is an Important Determinant of Ethinylestradiol Glucuronide and Ethinylestradiol Sulfate Pharmacokinetics
      Maciej J. Zamek-Gliszczynski, Jeffrey S. Day, Kathleen M. Hillgren and Diane L. Phillips
      Drug Metabolism and Disposition October 2011, 39 (10) 1794-1800; DOI: https://doi.org/10.1124/dmd.111.040162
  5. Piquette-Miller, Micheline

    1. You have access
      Mechanisms of Reduced Maternal and Fetal Lopinavir Exposure in a Rat Model of Gestational Diabetes
      Gregory J. Anger and Micheline Piquette-Miller
      Drug Metabolism and Disposition October 2011, 39 (10) 1850-1859; DOI: https://doi.org/10.1124/dmd.111.040626
  6. Plée-Gautier, Emmanuelle

    1. You have access
      CYP4F3B Expression Is Associated with Differentiation of HepaRG Human Hepatocytes and Unaffected by Fatty Acid Overload
      Stéphanie Madec, Virginie Cerec, Emmanuelle Plée-Gautier, Joseph Antoun, Denise Glaise, Jean-Pierre Salaun, Christiane Guguen-Guillouzo and Anne Corlu
      Drug Metabolism and Disposition October 2011, 39 (10) 1987-1996; DOI: https://doi.org/10.1124/dmd.110.036848

R

  1. Radominska-Pandya, Anna

    1. You have access
      Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
      Krishna C. Chimalakonda, Stacie M. Bratton, Vi-Huyen Le, Kan Hui Yiew, Anna Dineva, Cindy L. Moran, Laura P. James, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2011, 39 (10) 1967-1976; DOI: https://doi.org/10.1124/dmd.111.040709
  2. Rasmussen, Birgitte Buur

    1. You have access
      Metabolite Profiles of Degarelix, a New Gonadotropin-Releasing Hormone Receptor Antagonist, in Rat, Dog, and Monkey
      Anders Sonesson, Wolfgang Koechling, Jacek Stalewski, László B. Tankó and Birgitte Buur Rasmussen
      Drug Metabolism and Disposition October 2011, 39 (10) 1895-1903; DOI: https://doi.org/10.1124/dmd.111.039883
  3. Rodrigues, David

    1. You have access
      Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein Expression
      Martin Mahro, Catarina Coelho, José Trincão, David Rodrigues, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Maria João Romão and Silke Leimkühler
      Drug Metabolism and Disposition October 2011, 39 (10) 1939-1945; DOI: https://doi.org/10.1124/dmd.111.040873
  4. Romão, Maria João

    1. You have access
      Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein Expression
      Martin Mahro, Catarina Coelho, José Trincão, David Rodrigues, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Maria João Romão and Silke Leimkühler
      Drug Metabolism and Disposition October 2011, 39 (10) 1939-1945; DOI: https://doi.org/10.1124/dmd.111.040873
  5. Rosen, Gerald M.

    1. You have access
      Clearance and Biodistribution of Liposomally Encapsulated Nitroxides: A Model for Targeted Delivery of Electron Paramagnetic Resonance Imaging Probes to Tumors
      Scott R. Burks, Eric A. Legenzov, Gerald M. Rosen and Joseph P. Y. Kao
      Drug Metabolism and Disposition October 2011, 39 (10) 1961-1966; DOI: https://doi.org/10.1124/dmd.111.039636
  6. Rowland, Malcolm

    1. You have access
      Measurement of Binding of Basic Drugs to Acidic Phospholipids Using Surface Plasmon Resonance and Incorporation of the Data into Mechanistic Tissue Composition Equations to Predict Steady-State Volume of Distribution
      Helen Small, Iain Gardner, Hannah M. Jones, John Davis and Malcolm Rowland
      Drug Metabolism and Disposition October 2011, 39 (10) 1789-1793; DOI: https://doi.org/10.1124/dmd.111.040253

S

  1. Saggu, Miguel

    1. You have access
      Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein Expression
      Martin Mahro, Catarina Coelho, José Trincão, David Rodrigues, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Maria João Romão and Silke Leimkühler
      Drug Metabolism and Disposition October 2011, 39 (10) 1939-1945; DOI: https://doi.org/10.1124/dmd.111.040873
  2. Saigusa, Daisuke

    1. You have access
      Functional Characterization of CYP2B6 Allelic Variants in Demethylation of Antimalarial Artemether
      Masashi Honda, Yuka Muroi, Yuichiro Tamaki, Daisuke Saigusa, Naoto Suzuki, Yoshihisa Tomioka, Yoichi Matsubara, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition October 2011, 39 (10) 1860-1865; DOI: https://doi.org/10.1124/dmd.111.040352
  3. Saito, Motoko

    1. You have access
      Distribution of KAI-9803, a Novel δ-Protein Kinase C Inhibitor, after Intravenous Administration to Rats
      Yoshihiro Miyaji, Sarah Walter, Leon Chen, Atsushi Kurihara, Tomoko Ishizuka, Motoko Saito, Kenji Kawai and Osamu Okazaki
      Drug Metabolism and Disposition October 2011, 39 (10) 1946-1953; DOI: https://doi.org/10.1124/dmd.111.040725
  4. Salaun, Jean-Pierre

    1. You have access
      CYP4F3B Expression Is Associated with Differentiation of HepaRG Human Hepatocytes and Unaffected by Fatty Acid Overload
      Stéphanie Madec, Virginie Cerec, Emmanuelle Plée-Gautier, Joseph Antoun, Denise Glaise, Jean-Pierre Salaun, Christiane Guguen-Guillouzo and Anne Corlu
      Drug Metabolism and Disposition October 2011, 39 (10) 1987-1996; DOI: https://doi.org/10.1124/dmd.110.036848
  5. Sheikh-Bahaei, Shahab

    1. You have access
      Enabling Clearance Predictions to Emerge from In Silico Actions of Quasi-Autonomous Hepatocyte Components
      Shahab Sheikh-Bahaei and C. Anthony Hunt
      Drug Metabolism and Disposition October 2011, 39 (10) 1910-1920; DOI: https://doi.org/10.1124/dmd.111.038703
  6. Shin, Young

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  7. Small, Helen

    1. You have access
      Measurement of Binding of Basic Drugs to Acidic Phospholipids Using Surface Plasmon Resonance and Incorporation of the Data into Mechanistic Tissue Composition Equations to Predict Steady-State Volume of Distribution
      Helen Small, Iain Gardner, Hannah M. Jones, John Davis and Malcolm Rowland
      Drug Metabolism and Disposition October 2011, 39 (10) 1789-1793; DOI: https://doi.org/10.1124/dmd.111.040253
  8. Sonesson, Anders

    1. You have access
      Metabolite Profiles of Degarelix, a New Gonadotropin-Releasing Hormone Receptor Antagonist, in Rat, Dog, and Monkey
      Anders Sonesson, Wolfgang Koechling, Jacek Stalewski, László B. Tankó and Birgitte Buur Rasmussen
      Drug Metabolism and Disposition October 2011, 39 (10) 1895-1903; DOI: https://doi.org/10.1124/dmd.111.039883
  9. Sowell, C. Gregory

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
  10. Stalewski, Jacek

    1. You have access
      Metabolite Profiles of Degarelix, a New Gonadotropin-Releasing Hormone Receptor Antagonist, in Rat, Dog, and Monkey
      Anders Sonesson, Wolfgang Koechling, Jacek Stalewski, László B. Tankó and Birgitte Buur Rasmussen
      Drug Metabolism and Disposition October 2011, 39 (10) 1895-1903; DOI: https://doi.org/10.1124/dmd.111.039883
  11. Sun, Shiqing

    1. You have access
      Thioacetamide Intoxication Triggers Transcriptional Up-Regulation but Enzyme Inactivation of UDP-Glucuronosyltransferases
      Haiping Hao, Lifang Zhang, Shan Jiang, Shiqing Sun, Ping Gong, Yuan Xie, Xueyan Zhou and Guangji Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1815-1822; DOI: https://doi.org/10.1124/dmd.111.039172
  12. Suzuki, Masayuki

    1. You have access
      Pharmacokinetic and Pharmacodynamic Modeling of the Effect of an Sodium-Glucose Cotransporter Inhibitor, Phlorizin, on Renal Glucose Transport in Rats
      Koji Yamaguchi, Motohiro Kato, Masayuki Suzuki, Kimie Asanuma, Yoshinori Aso, Sachiya Ikeda and Masaki Ishigai
      Drug Metabolism and Disposition October 2011, 39 (10) 1801-1807; DOI: https://doi.org/10.1124/dmd.111.040048
  13. Suzuki, Naoto

    1. You have access
      Functional Characterization of CYP2B6 Allelic Variants in Demethylation of Antimalarial Artemether
      Masashi Honda, Yuka Muroi, Yuichiro Tamaki, Daisuke Saigusa, Naoto Suzuki, Yoshihisa Tomioka, Yoichi Matsubara, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition October 2011, 39 (10) 1860-1865; DOI: https://doi.org/10.1124/dmd.111.040352

T

  1. Tamaki, Yuichiro

    1. You have access
      Functional Characterization of CYP2B6 Allelic Variants in Demethylation of Antimalarial Artemether
      Masashi Honda, Yuka Muroi, Yuichiro Tamaki, Daisuke Saigusa, Naoto Suzuki, Yoshihisa Tomioka, Yoichi Matsubara, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition October 2011, 39 (10) 1860-1865; DOI: https://doi.org/10.1124/dmd.111.040352
  2. Tankó, László B.

    1. You have access
      Metabolite Profiles of Degarelix, a New Gonadotropin-Releasing Hormone Receptor Antagonist, in Rat, Dog, and Monkey
      Anders Sonesson, Wolfgang Koechling, Jacek Stalewski, László B. Tankó and Birgitte Buur Rasmussen
      Drug Metabolism and Disposition October 2011, 39 (10) 1895-1903; DOI: https://doi.org/10.1124/dmd.111.039883
  3. Templeton, Ian E.

    1. You have access
      Predictive Utility of In Vitro Rifampin Induction Data Generated in Fresh and Cryopreserved Human Hepatocytes, Fa2N-4, and HepaRG Cells
      Ian E. Templeton, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition October 2011, 39 (10) 1921-1929; DOI: https://doi.org/10.1124/dmd.111.040824
  4. Teng, Yang

    1. You have access
      Enhancement of Oral Bioavailability of 20(S)-Ginsenoside Rh2 through Improved Understanding of Its Absorption and Efflux Mechanisms
      Zhen Yang, Song Gao, Jingrong Wang, Taijun Yin, Yang Teng, Baojian Wu, Ming You, Zhihong Jiang and Ming Hu
      Drug Metabolism and Disposition October 2011, 39 (10) 1866-1872; DOI: https://doi.org/10.1124/dmd.111.040006
  5. Terao, Mineko

    1. You have access
      Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein Expression
      Martin Mahro, Catarina Coelho, José Trincão, David Rodrigues, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Maria João Romão and Silke Leimkühler
      Drug Metabolism and Disposition October 2011, 39 (10) 1939-1945; DOI: https://doi.org/10.1124/dmd.111.040873
  6. Tomioka, Yoshihisa

    1. You have access
      Functional Characterization of CYP2B6 Allelic Variants in Demethylation of Antimalarial Artemether
      Masashi Honda, Yuka Muroi, Yuichiro Tamaki, Daisuke Saigusa, Naoto Suzuki, Yoshihisa Tomioka, Yoichi Matsubara, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition October 2011, 39 (10) 1860-1865; DOI: https://doi.org/10.1124/dmd.111.040352
  7. Trincão, José

    1. You have access
      Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein Expression
      Martin Mahro, Catarina Coelho, José Trincão, David Rodrigues, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Maria João Romão and Silke Leimkühler
      Drug Metabolism and Disposition October 2011, 39 (10) 1939-1945; DOI: https://doi.org/10.1124/dmd.111.040873

W

  1. Walter, Sarah

    1. You have access
      Distribution of KAI-9803, a Novel δ-Protein Kinase C Inhibitor, after Intravenous Administration to Rats
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      Drug Metabolism and Disposition October 2011, 39 (10) 1946-1953; DOI: https://doi.org/10.1124/dmd.111.040725
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    1. You have access
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      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
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      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
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      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840
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      Drug Metabolism and Disposition October 2011, 39 (10) 1866-1872; DOI: https://doi.org/10.1124/dmd.111.040006

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  1. Xie, Yuan

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      Thioacetamide Intoxication Triggers Transcriptional Up-Regulation but Enzyme Inactivation of UDP-Glucuronosyltransferases
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      Drug Metabolism and Disposition October 2011, 39 (10) 1815-1822; DOI: https://doi.org/10.1124/dmd.111.039172

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  1. Yabe, Yoshiyuki

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      Kinetic Characterization of Rat Hepatic Uptake of 16 Actively Transported Drugs
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      Drug Metabolism and Disposition October 2011, 39 (10) 1808-1814; DOI: https://doi.org/10.1124/dmd.111.040477
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      Drug Metabolism and Disposition October 2011, 39 (10) 1801-1807; DOI: https://doi.org/10.1124/dmd.111.040048
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      Pharmacokinetics, Pharmacodynamics, Metabolism, Distribution, and Excretion of Carfilzomib in Rats
      Jinfu Yang, Zhengping Wang, Ying Fang, Jing Jiang, Frances Zhao, Hansen Wong, Mark K. Bennett, Christopher J. Molineaux and Christopher J. Kirk
      Drug Metabolism and Disposition October 2011, 39 (10) 1873-1882; DOI: https://doi.org/10.1124/dmd.111.039164
  4. Yang, Zhen

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      Enhancement of Oral Bioavailability of 20(S)-Ginsenoside Rh2 through Improved Understanding of Its Absorption and Efflux Mechanisms
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      Drug Metabolism and Disposition October 2011, 39 (10) 1866-1872; DOI: https://doi.org/10.1124/dmd.111.040006
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      Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
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      Drug Metabolism and Disposition October 2011, 39 (10) 1967-1976; DOI: https://doi.org/10.1124/dmd.111.040709
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      Enhancement of Oral Bioavailability of 20(S)-Ginsenoside Rh2 through Improved Understanding of Its Absorption and Efflux Mechanisms
      Zhen Yang, Song Gao, Jingrong Wang, Taijun Yin, Yang Teng, Baojian Wu, Ming You, Zhihong Jiang and Ming Hu
      Drug Metabolism and Disposition October 2011, 39 (10) 1866-1872; DOI: https://doi.org/10.1124/dmd.111.040006
  7. You, Ming

    1. You have access
      Enhancement of Oral Bioavailability of 20(S)-Ginsenoside Rh2 through Improved Understanding of Its Absorption and Efflux Mechanisms
      Zhen Yang, Song Gao, Jingrong Wang, Taijun Yin, Yang Teng, Baojian Wu, Ming You, Zhihong Jiang and Ming Hu
      Drug Metabolism and Disposition October 2011, 39 (10) 1866-1872; DOI: https://doi.org/10.1124/dmd.111.040006
  8. Young, Wendy B.

    1. You have access
      Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
      Lichuan Liu, Jason S. Halladay, Young Shin, Susan Wong, Melis Coraggio, Hank La, Matthew Baumgardner, Hoa Le, Sashi Gopaul, Jason Boggs, Peter Kuebler, John C. Davis, X. Charlene Liao, Joseph W. Lubach, Alan Deese, C. Gregory Sowell, Kevin S. Currie, Wendy B. Young, S. Cyrus Khojasteh, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition October 2011, 39 (10) 1840-1849; DOI: https://doi.org/10.1124/dmd.111.040840

Z

  1. Zamek-Gliszczynski, Maciej J.

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      Efflux Transport Is an Important Determinant of Ethinylestradiol Glucuronide and Ethinylestradiol Sulfate Pharmacokinetics
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      Drug Metabolism and Disposition October 2011, 39 (10) 1794-1800; DOI: https://doi.org/10.1124/dmd.111.040162
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      Brain Regional Pharmacokinetics of p-Aminosalicylic Acid and Its N-Acetylated Metabolite: Effectiveness in Chelating Brain Manganese
      Lan Hong, Wendy Jiang, Hao Pan, Yueming Jiang, Su Zeng and Wei Zheng
      Drug Metabolism and Disposition October 2011, 39 (10) 1904-1909; DOI: https://doi.org/10.1124/dmd.111.040915
  3. Zhang, Lifang

    1. You have access
      Thioacetamide Intoxication Triggers Transcriptional Up-Regulation but Enzyme Inactivation of UDP-Glucuronosyltransferases
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      Drug Metabolism and Disposition October 2011, 39 (10) 1815-1822; DOI: https://doi.org/10.1124/dmd.111.039172
  4. Zhao, Frances

    1. You have access
      Pharmacokinetics, Pharmacodynamics, Metabolism, Distribution, and Excretion of Carfilzomib in Rats
      Jinfu Yang, Zhengping Wang, Ying Fang, Jing Jiang, Frances Zhao, Hansen Wong, Mark K. Bennett, Christopher J. Molineaux and Christopher J. Kirk
      Drug Metabolism and Disposition October 2011, 39 (10) 1873-1882; DOI: https://doi.org/10.1124/dmd.111.039164
  5. Zheng, Wei

    1. You have access
      Brain Regional Pharmacokinetics of p-Aminosalicylic Acid and Its N-Acetylated Metabolite: Effectiveness in Chelating Brain Manganese
      Lan Hong, Wendy Jiang, Hao Pan, Yueming Jiang, Su Zeng and Wei Zheng
      Drug Metabolism and Disposition October 2011, 39 (10) 1904-1909; DOI: https://doi.org/10.1124/dmd.111.040915
  6. Zhou, Diansong

    1. You have access
      In Vitro and In Vivo Metabolism of a Selective δ-Opioid Receptor
      Jian Guo, Chungang Gu, Diansong Zhou, Charles S. Elmore, Khanh H. Bui and Scott W. Grimm
      Drug Metabolism and Disposition October 2011, 39 (10) 1883-1894; DOI: https://doi.org/10.1124/dmd.111.040980
  7. Zhou, Xueyan

    1. You have access
      Thioacetamide Intoxication Triggers Transcriptional Up-Regulation but Enzyme Inactivation of UDP-Glucuronosyltransferases
      Haiping Hao, Lifang Zhang, Shan Jiang, Shiqing Sun, Ping Gong, Yuan Xie, Xueyan Zhou and Guangji Wang
      Drug Metabolism and Disposition October 2011, 39 (10) 1815-1822; DOI: https://doi.org/10.1124/dmd.111.039172
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Drug Metabolism and Disposition: 39 (10)
Drug Metabolism and Disposition
Vol. 39, Issue 10
1 Oct 2011
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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