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Research ArticleArticle

Q172H Replacement Overcomes Effects on the Metabolism of Cyclophosphamide and Efavirenz Caused by CYP2B6 Variant with Arg262

Noritaka Ariyoshi, Miyuki Ohara, Mayumi Kaneko, Sakino Afuso, Takuya Kumamoto, Hiroyoshi Nakamura, Itsuko Ishii, Tsutomu Ishikawa and Mitsukazu Kitada
Drug Metabolism and Disposition November 2011, 39 (11) 2045-2048; DOI: https://doi.org/10.1124/dmd.111.039586

Article Information

vol. 39 no. 11 2045-2048
DOI 
https://doi.org/10.1124/dmd.111.039586
PubMed 
21821736
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 16, 2011
  • Accepted August 5, 2011
  • Published online October 18, 2011.

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Copyright & Usage 
Copyright © 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Noritaka Ariyoshi,
  2. Miyuki Ohara,
  3. Mayumi Kaneko,
  4. Sakino Afuso,
  5. Takuya Kumamoto,
  6. Hiroyoshi Nakamura,
  7. Itsuko Ishii,
  8. Tsutomu Ishikawa and
  9. Mitsukazu Kitada
  1. Division of Pharmacy, University Hospital, Chiba University School of Medicine (N.A., H.N., M.Ki.), Department of Clinical Pharmacology (M.O., M.Ka., S.A., I.I.), and Department of Medicinal Organic Chemistry (T.K., T.I.), Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan
  1. Address correspondence to:
    Dr. Noritaka Ariyoshi, Division of Pharmacy, University Hospital, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, Japan. E-mail: ariyoshi{at}faculty.chiba-u.jp
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UNIQUE EFFECTS OF Q172H ON CATALYTIC ACTIVITY OF CYP2B6

Noritaka Ariyoshi, Miyuki Ohara, Mayumi Kaneko, Sakino Afuso, Takuya Kumamoto, Hiroyoshi Nakamura, Itsuko Ishii, Tsutomu Ishikawa and Mitsukazu Kitada
Drug Metabolism and Disposition November 1, 2011, 39 (11) 2045-2048; DOI: https://doi.org/10.1124/dmd.111.039586
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