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Index by author

December 01, 2011; Volume 39,Issue 12

A

  1. Afdhal, Nezam H.

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

  2. Ahnoff, Martin

    1. Development of a Highly Sensitive Method Using Liquid Chromatography-Multiple Reaction Monitoring to Quantify Membrane P-Glycoprotein in Biological Matrices and Relationship to Transport Function
      Tasso Miliotis, Liaqat Ali, Johan E. Palm, Anders J. Lundqvist, Martin Ahnoff, Tommy B. Andersson and Constanze Hilgendorf
      Drug Metabolism and Disposition December 2011, 39 (12) 2440-2449; DOI: https://doi.org/10.1124/dmd.111.040774

  3. Alhonen, Leena

    1. Complex N-Acetylation of Triethylenetetramine
      Marc Cerrada-Gimenez, Janne Weisell, Mervi T. Hyvönen, Myung Hee Park, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition December 2011, 39 (12) 2242-2249; DOI: https://doi.org/10.1124/dmd.111.041798

  4. Ali, Liaqat

    1. Development of a Highly Sensitive Method Using Liquid Chromatography-Multiple Reaction Monitoring to Quantify Membrane P-Glycoprotein in Biological Matrices and Relationship to Transport Function
      Tasso Miliotis, Liaqat Ali, Johan E. Palm, Anders J. Lundqvist, Martin Ahnoff, Tommy B. Andersson and Constanze Hilgendorf
      Drug Metabolism and Disposition December 2011, 39 (12) 2440-2449; DOI: https://doi.org/10.1124/dmd.111.040774

  5. Andersson, Tommy B.

    1. Development of a Highly Sensitive Method Using Liquid Chromatography-Multiple Reaction Monitoring to Quantify Membrane P-Glycoprotein in Biological Matrices and Relationship to Transport Function
      Tasso Miliotis, Liaqat Ali, Johan E. Palm, Anders J. Lundqvist, Martin Ahnoff, Tommy B. Andersson and Constanze Hilgendorf
      Drug Metabolism and Disposition December 2011, 39 (12) 2440-2449; DOI: https://doi.org/10.1124/dmd.111.040774

  6. Aoyama, Shinsuke

    1. Involvement of Different Human Glutathione Transferase Isoforms in the Glutathione Conjugation of Reactive Metabolites of Troglitazone
      Ran Okada, Kazuya Maeda, Takahito Nishiyama, Shinsuke Aoyama, Zenzaburo Tozuka, Akira Hiratsuka, Toshihiko Ikeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2290-2297; DOI: https://doi.org/10.1124/dmd.111.040469

  7. Arlt, Volker M.

    1. Effect of Hepatic Cytochrome P450 (P450) Oxidoreductase Deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 Reductase Conditional Null Mice
      Volker M. Arlt, Rajinder Singh, Marie Stiborová, Gonçalo Gamboa da Costa, Eva Frei, James D. Evans, Peter B. Farmer, C. Roland Wolf, Colin J. Henderson and David H. Phillips
      Drug Metabolism and Disposition December 2011, 39 (12) 2169-2173; DOI: https://doi.org/10.1124/dmd.111.041343

B

  1. Bacon, James A.

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

  2. Ballard, Peter

    1. Correction for Nonspecific Binding to Various Components of Ultrafiltration Apparatus and Impact on Estimating In Vivo Rat Clearance for a Congeneric Series of 5-Ethyl, 5-n-Alkyl Barbituric Acids
      Peter Ballard and Malcolm Rowland
      Drug Metabolism and Disposition December 2011, 39 (12) 2165-2168; DOI: https://doi.org/10.1124/dmd.111.040683

  3. Barr, John T.

    1. Inhibition of Human Liver Aldehyde Oxidase: Implications for Potential Drug-Drug Interactions
      John T. Barr and Jeffrey P. Jones
      Drug Metabolism and Disposition December 2011, 39 (12) 2381-2386; DOI: https://doi.org/10.1124/dmd.111.041806

  4. Belle, Steven H.

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

  5. Bender, David M.

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

  6. Bies, Robert R.

    1. Cardiac Arrest and Therapeutic Hypothermia Decrease Isoform-Specific Cytochrome P450 Drug Metabolism
      Jiangquan Zhou, Philip E. Empey, Robert R. Bies, Patrick M. Kochanek and Samuel M. Poloyac
      Drug Metabolism and Disposition December 2011, 39 (12) 2209-2218; DOI: https://doi.org/10.1124/dmd.111.040642

  7. Boerma, Jan Simon

    1. Role of Residue 87 in the Activity and Regioselectivity of Clozapine Metabolism by Drug-Metabolizing CYP102A1 M11H: Application for Structural Characterization of Clozapine GSH Conjugates
      Vanina Rea, Sanja Dragovic, Jan Simon Boerma, Frans J. J. de Kanter, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition December 2011, 39 (12) 2411-2420; DOI: https://doi.org/10.1124/dmd.111.041046

  8. Buchheit, Daniela

    1. Production of Ibuprofen Acyl Glucosides by Human UGT2B7
      Daniela Buchheit, Călin-Aurel Drăgan, Ellen I. Schmitt and Matthias Bureik
      Drug Metabolism and Disposition December 2011, 39 (12) 2174-2181; DOI: https://doi.org/10.1124/dmd.111.041640

  9. Burchell, Brian

    1. A Novel Method for the Immunoquantification of UDP-Glucuronosyltransferases in Human Tissue
      Alison M. Milne, Brian Burchell and Michael W. H. Coughtrie
      Drug Metabolism and Disposition December 2011, 39 (12) 2258-2263; DOI: https://doi.org/10.1124/dmd.111.041699

  10. Bureik, Matthias

    1. Production of Ibuprofen Acyl Glucosides by Human UGT2B7
      Daniela Buchheit, Călin-Aurel Drăgan, Ellen I. Schmitt and Matthias Bureik
      Drug Metabolism and Disposition December 2011, 39 (12) 2174-2181; DOI: https://doi.org/10.1124/dmd.111.041640

  11. Burrell, R.

    1. Studies to Further Investigate the Inhibition of Human Liver Microsomal CYP2C8 by the Acyl-β-Glucuronide of Gemfibrozil
      S. M. Jenkins, T. Zvyaga, S. R. Johnson, J. Hurley, A. Wagner, R. Burrell, W. Turley, J. E. Leet, T. Philip and A. D. Rodrigues
      Drug Metabolism and Disposition December 2011, 39 (12) 2421-2430; DOI: https://doi.org/10.1124/dmd.111.041947

C

  1. Cali, James J.

    1. Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition
      Poncho L. Meisenheimer, H. Tetsuo Uyeda, Dongping Ma, Mary Sobol, Mark G. McDougall, Cesear Corona, Dan Simpson, Dieter H. Klaubert and James J. Cali
      Drug Metabolism and Disposition December 2011, 39 (12) 2403-2410; DOI: https://doi.org/10.1124/dmd.111.041541

  2. Canet, Mark J.

    1. Variations in ATP-Binding Cassette Transporter Regulation during the Progression of Human Nonalcoholic Fatty Liver Disease
      Rhiannon N. Hardwick, Craig D. Fisher, Mark J. Canet, George L. Scheffer and Nathan J. Cherrington
      Drug Metabolism and Disposition December 2011, 39 (12) 2395-2402; DOI: https://doi.org/10.1124/dmd.111.041012

  3. Carew, Michael W.

    1. Monomethylarsenic Diglutathione Transport by the Human Multidrug Resistance Protein 1 (MRP1/ABCC1)
      Michael W. Carew, Hua Naranmandura, Caley B. Shukalek, X. Chris Le and Elaine M. Leslie
      Drug Metabolism and Disposition December 2011, 39 (12) 2298-2304; DOI: https://doi.org/10.1124/dmd.111.041673

  4. Cerrada-Gimenez, Marc

    1. Complex N-Acetylation of Triethylenetetramine
      Marc Cerrada-Gimenez, Janne Weisell, Mervi T. Hyvönen, Myung Hee Park, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition December 2011, 39 (12) 2242-2249; DOI: https://doi.org/10.1124/dmd.111.041798

  5. Cherrington, Nathan J.

    1. Variations in ATP-Binding Cassette Transporter Regulation during the Progression of Human Nonalcoholic Fatty Liver Disease
      Rhiannon N. Hardwick, Craig D. Fisher, Mark J. Canet, George L. Scheffer and Nathan J. Cherrington
      Drug Metabolism and Disposition December 2011, 39 (12) 2395-2402; DOI: https://doi.org/10.1124/dmd.111.041012

  6. Coleman, T.

    1. Intestinal Ciprofloxacin Efflux: The Role of Breast Cancer Resistance Protein (ABCG2)
      I. S. Haslam, J. A. Wright, D. A. O'Reilly, D. J. Sherlock, T. Coleman and N. L. Simmons
      Drug Metabolism and Disposition December 2011, 39 (12) 2321-2328; DOI: https://doi.org/10.1124/dmd.111.038323

  7. Collier, Ann C.

    1. Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6, and 2C9 by Ritonavir or Nelfinavir
      Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj Desai, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2011, 39 (12) 2329-2337; DOI: https://doi.org/10.1124/dmd.111.038646

  8. Commandeur, Jan N. M.

    1. Role of Residue 87 in the Activity and Regioselectivity of Clozapine Metabolism by Drug-Metabolizing CYP102A1 M11H: Application for Structural Characterization of Clozapine GSH Conjugates
      Vanina Rea, Sanja Dragovic, Jan Simon Boerma, Frans J. J. de Kanter, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition December 2011, 39 (12) 2411-2420; DOI: https://doi.org/10.1124/dmd.111.041046

  9. Corona, Cesear

    1. Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition
      Poncho L. Meisenheimer, H. Tetsuo Uyeda, Dongping Ma, Mary Sobol, Mark G. McDougall, Cesear Corona, Dan Simpson, Dieter H. Klaubert and James J. Cali
      Drug Metabolism and Disposition December 2011, 39 (12) 2403-2410; DOI: https://doi.org/10.1124/dmd.111.041541

  10. Coughtrie, Michael W. H.

    1. A Novel Method for the Immunoquantification of UDP-Glucuronosyltransferases in Human Tissue
      Alison M. Milne, Brian Burchell and Michael W. H. Coughtrie
      Drug Metabolism and Disposition December 2011, 39 (12) 2258-2263; DOI: https://doi.org/10.1124/dmd.111.041699

  11. Courtney, Paul F.

    1. Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4
      Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2361-2369; DOI: https://doi.org/10.1124/dmd.111.041814

D

  1. Dahal, Upendra P.

    1. Small Molecule Quantification by Liquid Chromatography-Mass Spectrometry for Metabolites of Drugs and Drug Candidates
      Upendra P. Dahal, Jeffrey P. Jones, John A. Davis and Dan A. Rock
      Drug Metabolism and Disposition December 2011, 39 (12) 2355-2360; DOI: https://doi.org/10.1124/dmd.111.040865

  2. Dalgaard, Lars

    1. Biosynthesis and Identification of an N-Oxide/N-Glucuronide Metabolite and First Synthesis of an N-O-Glucuronide Metabolite of Lu AA21004
      Henriette Kold Uldam, Martin Juhl, Henrik Pedersen and Lars Dalgaard
      Drug Metabolism and Disposition December 2011, 39 (12) 2264-2274; DOI: https://doi.org/10.1124/dmd.111.040428

  3. Danhof, Meindert

    1. Systemic and Direct Nose-to-Brain Transport Pharmacokinetic Model for Remoxipride after Intravenous and Intranasal Administration
      Jasper Stevens, Bart A. Ploeger, Piet H. van der Graaf, Meindert Danhof and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition December 2011, 39 (12) 2275-2282; DOI: https://doi.org/10.1124/dmd.111.040782

  4. Davis, John A.

    1. Small Molecule Quantification by Liquid Chromatography-Mass Spectrometry for Metabolites of Drugs and Drug Candidates
      Upendra P. Dahal, Jeffrey P. Jones, John A. Davis and Dan A. Rock
      Drug Metabolism and Disposition December 2011, 39 (12) 2355-2360; DOI: https://doi.org/10.1124/dmd.111.040865

  5. Day, Robert

    1. Excretion, Metabolism, and Pharmacokinetics of CP-945,598, a Selective Cannabinoid Receptor Antagonist, in Rats, Mice, and Dogs
      Zhuang Miao, Dennis O. Scott, David A. Griffith, Robert Day and Chandra Prakash
      Drug Metabolism and Disposition December 2011, 39 (12) 2191-2208; DOI: https://doi.org/10.1124/dmd.111.040360

  6. Debori, Yasuyuki

    1. Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4
      Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2361-2369; DOI: https://doi.org/10.1124/dmd.111.041814

  7. de Kanter, Frans J. J.

    1. Role of Residue 87 in the Activity and Regioselectivity of Clozapine Metabolism by Drug-Metabolizing CYP102A1 M11H: Application for Structural Characterization of Clozapine GSH Conjugates
      Vanina Rea, Sanja Dragovic, Jan Simon Boerma, Frans J. J. de Kanter, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition December 2011, 39 (12) 2411-2420; DOI: https://doi.org/10.1124/dmd.111.041046

  8. de Lange, Elizabeth C. M.

    1. Systemic and Direct Nose-to-Brain Transport Pharmacokinetic Model for Remoxipride after Intravenous and Intranasal Administration
      Jasper Stevens, Bart A. Ploeger, Piet H. van der Graaf, Meindert Danhof and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition December 2011, 39 (12) 2275-2282; DOI: https://doi.org/10.1124/dmd.111.040782

  9. Desai, Pankaj

    1. Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6, and 2C9 by Ritonavir or Nelfinavir
      Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj Desai, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2011, 39 (12) 2329-2337; DOI: https://doi.org/10.1124/dmd.111.038646

  10. Dew, Tristan P.

    1. Absorption and Metabolism of Chlorogenic Acids in Cultured Gastric Epithelial Monolayers
      Tracy L. Farrell, Tristan P. Dew, Laure Poquet, Peter Hanson and Gary Williamson
      Drug Metabolism and Disposition December 2011, 39 (12) 2338-2346; DOI: https://doi.org/10.1124/dmd.111.040147

  11. Dixit, Vaishali

    1. Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6, and 2C9 by Ritonavir or Nelfinavir
      Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj Desai, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2011, 39 (12) 2329-2337; DOI: https://doi.org/10.1124/dmd.111.038646

  12. Doo, Edward

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

  13. Drăgan, Călin-Aurel

    1. Production of Ibuprofen Acyl Glucosides by Human UGT2B7
      Daniela Buchheit, Călin-Aurel Drăgan, Ellen I. Schmitt and Matthias Bureik
      Drug Metabolism and Disposition December 2011, 39 (12) 2174-2181; DOI: https://doi.org/10.1124/dmd.111.041640

  14. Dragovic, Sanja

    1. Role of Residue 87 in the Activity and Regioselectivity of Clozapine Metabolism by Drug-Metabolizing CYP102A1 M11H: Application for Structural Characterization of Clozapine GSH Conjugates
      Vanina Rea, Sanja Dragovic, Jan Simon Boerma, Frans J. J. de Kanter, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition December 2011, 39 (12) 2411-2420; DOI: https://doi.org/10.1124/dmd.111.041046

E

  1. Ehsani, Mariam E.

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

  2. Empey, Philip E.

    1. Cardiac Arrest and Therapeutic Hypothermia Decrease Isoform-Specific Cytochrome P450 Drug Metabolism
      Jiangquan Zhou, Philip E. Empey, Robert R. Bies, Patrick M. Kochanek and Samuel M. Poloyac
      Drug Metabolism and Disposition December 2011, 39 (12) 2209-2218; DOI: https://doi.org/10.1124/dmd.111.040642

  3. Ethirajulu, Kantharaj

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

  4. Evans, James D.

    1. Effect of Hepatic Cytochrome P450 (P450) Oxidoreductase Deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 Reductase Conditional Null Mice
      Volker M. Arlt, Rajinder Singh, Marie Stiborová, Gonçalo Gamboa da Costa, Eva Frei, James D. Evans, Peter B. Farmer, C. Roland Wolf, Colin J. Henderson and David H. Phillips
      Drug Metabolism and Disposition December 2011, 39 (12) 2169-2173; DOI: https://doi.org/10.1124/dmd.111.041343

F

  1. Farmer, Peter B.

    1. Effect of Hepatic Cytochrome P450 (P450) Oxidoreductase Deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 Reductase Conditional Null Mice
      Volker M. Arlt, Rajinder Singh, Marie Stiborová, Gonçalo Gamboa da Costa, Eva Frei, James D. Evans, Peter B. Farmer, C. Roland Wolf, Colin J. Henderson and David H. Phillips
      Drug Metabolism and Disposition December 2011, 39 (12) 2169-2173; DOI: https://doi.org/10.1124/dmd.111.041343

  2. Farrell, Tracy L.

    1. Absorption and Metabolism of Chlorogenic Acids in Cultured Gastric Epithelial Monolayers
      Tracy L. Farrell, Tristan P. Dew, Laure Poquet, Peter Hanson and Gary Williamson
      Drug Metabolism and Disposition December 2011, 39 (12) 2338-2346; DOI: https://doi.org/10.1124/dmd.111.040147

  3. Ferguson, C. S.

    1. Independent and Combined Effects of Ethanol Self-Administration and Nicotine Treatment on Hepatic CYP2E1 in African Green Monkeys
      C. S. Ferguson, S. Miksys, R. Palmour and R. F. Tyndale
      Drug Metabolism and Disposition December 2011, 39 (12) 2233-2241; DOI: https://doi.org/10.1124/dmd.111.040378

  4. Fisher, Craig D.

    1. Variations in ATP-Binding Cassette Transporter Regulation during the Progression of Human Nonalcoholic Fatty Liver Disease
      Rhiannon N. Hardwick, Craig D. Fisher, Mark J. Canet, George L. Scheffer and Nathan J. Cherrington
      Drug Metabolism and Disposition December 2011, 39 (12) 2395-2402; DOI: https://doi.org/10.1124/dmd.111.041012

  5. Frei, Eva

    1. Effect of Hepatic Cytochrome P450 (P450) Oxidoreductase Deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 Reductase Conditional Null Mice
      Volker M. Arlt, Rajinder Singh, Marie Stiborová, Gonçalo Gamboa da Costa, Eva Frei, James D. Evans, Peter B. Farmer, C. Roland Wolf, Colin J. Henderson and David H. Phillips
      Drug Metabolism and Disposition December 2011, 39 (12) 2169-2173; DOI: https://doi.org/10.1124/dmd.111.041343

  6. Fried, Michael. W.

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

G

  1. Gamboa da Costa, Gonçalo

    1. Effect of Hepatic Cytochrome P450 (P450) Oxidoreductase Deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 Reductase Conditional Null Mice
      Volker M. Arlt, Rajinder Singh, Marie Stiborová, Gonçalo Gamboa da Costa, Eva Frei, James D. Evans, Peter B. Farmer, C. Roland Wolf, Colin J. Henderson and David H. Phillips
      Drug Metabolism and Disposition December 2011, 39 (12) 2169-2173; DOI: https://doi.org/10.1124/dmd.111.041343

  2. Goh, Evelyn

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

  3. Griffith, David A.

    1. Excretion, Metabolism, and Pharmacokinetics of CP-945,598, a Selective Cannabinoid Receptor Antagonist, in Rats, Mice, and Dogs
      Zhuang Miao, Dennis O. Scott, David A. Griffith, Robert Day and Chandra Prakash
      Drug Metabolism and Disposition December 2011, 39 (12) 2191-2208; DOI: https://doi.org/10.1124/dmd.111.040360

  4. Grillo, Mark P.

    1. Effect of Culture Time on the Basal Expression Levels of Drug Transporters in Sandwich-Cultured Primary Rat Hepatocytes
      Eskouhie H. Tchaparian, Jessica S. Houghton, Craig Uyeda, Mark P. Grillo and Lixia Jin
      Drug Metabolism and Disposition December 2011, 39 (12) 2387-2394; DOI: https://doi.org/10.1124/dmd.111.039545

  5. Guo, Wen-Kai

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

H

  1. Hanson, Peter

    1. Absorption and Metabolism of Chlorogenic Acids in Cultured Gastric Epithelial Monolayers
      Tracy L. Farrell, Tristan P. Dew, Laure Poquet, Peter Hanson and Gary Williamson
      Drug Metabolism and Disposition December 2011, 39 (12) 2338-2346; DOI: https://doi.org/10.1124/dmd.111.040147

  2. Hardwick, Rhiannon N.

    1. Variations in ATP-Binding Cassette Transporter Regulation during the Progression of Human Nonalcoholic Fatty Liver Disease
      Rhiannon N. Hardwick, Craig D. Fisher, Mark J. Canet, George L. Scheffer and Nathan J. Cherrington
      Drug Metabolism and Disposition December 2011, 39 (12) 2395-2402; DOI: https://doi.org/10.1124/dmd.111.041012

  3. Haslam, I. S.

    1. Intestinal Ciprofloxacin Efflux: The Role of Breast Cancer Resistance Protein (ABCG2)
      I. S. Haslam, J. A. Wright, D. A. O'Reilly, D. J. Sherlock, T. Coleman and N. L. Simmons
      Drug Metabolism and Disposition December 2011, 39 (12) 2321-2328; DOI: https://doi.org/10.1124/dmd.111.038323

  4. Hawke, Roy L.

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

  5. Hee Park, Myung

    1. Complex N-Acetylation of Triethylenetetramine
      Marc Cerrada-Gimenez, Janne Weisell, Mervi T. Hyvönen, Myung Hee Park, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition December 2011, 39 (12) 2242-2249; DOI: https://doi.org/10.1124/dmd.111.041798

  6. Henderson, Colin J.

    1. Effect of Hepatic Cytochrome P450 (P450) Oxidoreductase Deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 Reductase Conditional Null Mice
      Volker M. Arlt, Rajinder Singh, Marie Stiborová, Gonçalo Gamboa da Costa, Eva Frei, James D. Evans, Peter B. Farmer, C. Roland Wolf, Colin J. Henderson and David H. Phillips
      Drug Metabolism and Disposition December 2011, 39 (12) 2169-2173; DOI: https://doi.org/10.1124/dmd.111.041343

  7. Hilgendorf, Constanze

    1. Development of a Highly Sensitive Method Using Liquid Chromatography-Multiple Reaction Monitoring to Quantify Membrane P-Glycoprotein in Biological Matrices and Relationship to Transport Function
      Tasso Miliotis, Liaqat Ali, Johan E. Palm, Anders J. Lundqvist, Martin Ahnoff, Tommy B. Andersson and Constanze Hilgendorf
      Drug Metabolism and Disposition December 2011, 39 (12) 2440-2449; DOI: https://doi.org/10.1124/dmd.111.040774

  8. Hiratsuka, Akira

    1. Involvement of Different Human Glutathione Transferase Isoforms in the Glutathione Conjugation of Reactive Metabolites of Troglitazone
      Ran Okada, Kazuya Maeda, Takahito Nishiyama, Shinsuke Aoyama, Zenzaburo Tozuka, Akira Hiratsuka, Toshihiko Ikeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2290-2297; DOI: https://doi.org/10.1124/dmd.111.040469

  9. Hisaka, Akihiro

    1. Analysis and Prediction of Drug Transfer into Human Milk Taking into Consideration Secretion and Reuptake Clearances across the Mammary Epithelia
      Hiroki Koshimichi, Kousei Ito, Akihiro Hisaka, Masashi Honma and Hiroshi Suzuki
      Drug Metabolism and Disposition December 2011, 39 (12) 2370-2380; DOI: https://doi.org/10.1124/dmd.111.040972

  10. Hollenberg, Paul F.

    1. Thr302 Is the Site for the Covalent Modification of Human Cytochrome P450 2B6 Leading to Mechanism-Based Inactivation by tert-Butylphenylacetylene
      Hsia-lien Lin, Haoming Zhang, Matthew J. Pratt-Hyatt and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2011, 39 (12) 2431-2439; DOI: https://doi.org/10.1124/dmd.111.042176

  11. Honma, Masashi

    1. Analysis and Prediction of Drug Transfer into Human Milk Taking into Consideration Secretion and Reuptake Clearances across the Mammary Epithelia
      Hiroki Koshimichi, Kousei Ito, Akihiro Hisaka, Masashi Honma and Hiroshi Suzuki
      Drug Metabolism and Disposition December 2011, 39 (12) 2370-2380; DOI: https://doi.org/10.1124/dmd.111.040972

  12. Houghton, Jessica S.

    1. Effect of Culture Time on the Basal Expression Levels of Drug Transporters in Sandwich-Cultured Primary Rat Hepatocytes
      Eskouhie H. Tchaparian, Jessica S. Houghton, Craig Uyeda, Mark P. Grillo and Lixia Jin
      Drug Metabolism and Disposition December 2011, 39 (12) 2387-2394; DOI: https://doi.org/10.1124/dmd.111.039545

  13. Hu, Yongjun

    1. Effect of Dose Escalation on the In Vivo Oral Absorption and Disposition of Glycylsarcosine in Wild-Type and Pept1 Knockout Mice
      Dilara Jappar, Yongjun Hu and David E. Smith
      Drug Metabolism and Disposition December 2011, 39 (12) 2250-2257; DOI: https://doi.org/10.1124/dmd.111.041087

  14. Hurley, J.

    1. Studies to Further Investigate the Inhibition of Human Liver Microsomal CYP2C8 by the Acyl-β-Glucuronide of Gemfibrozil
      S. M. Jenkins, T. Zvyaga, S. R. Johnson, J. Hurley, A. Wagner, R. Burrell, W. Turley, J. E. Leet, T. Philip and A. D. Rodrigues
      Drug Metabolism and Disposition December 2011, 39 (12) 2421-2430; DOI: https://doi.org/10.1124/dmd.111.041947

  15. Hyvönen, Mervi T.

    1. Complex N-Acetylation of Triethylenetetramine
      Marc Cerrada-Gimenez, Janne Weisell, Mervi T. Hyvönen, Myung Hee Park, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition December 2011, 39 (12) 2242-2249; DOI: https://doi.org/10.1124/dmd.111.041798

I

  1. Ikeda, Toshihiko

    1. Involvement of Different Human Glutathione Transferase Isoforms in the Glutathione Conjugation of Reactive Metabolites of Troglitazone
      Ran Okada, Kazuya Maeda, Takahito Nishiyama, Shinsuke Aoyama, Zenzaburo Tozuka, Akira Hiratsuka, Toshihiko Ikeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2290-2297; DOI: https://doi.org/10.1124/dmd.111.040469

  2. Imming, Peter

    1. CYP2C19 Progress Curve Analysis and Mechanism-Based Inactivation by Three Methylenedioxyphenyl Compounds
      Kaisa A. Salminen, Achim Meyer, Peter Imming and Hannu Raunio
      Drug Metabolism and Disposition December 2011, 39 (12) 2283-2289; DOI: https://doi.org/10.1124/dmd.111.041319

  3. Ito, Kousei

    1. Analysis and Prediction of Drug Transfer into Human Milk Taking into Consideration Secretion and Reuptake Clearances across the Mammary Epithelia
      Hiroki Koshimichi, Kousei Ito, Akihiro Hisaka, Masashi Honma and Hiroshi Suzuki
      Drug Metabolism and Disposition December 2011, 39 (12) 2370-2380; DOI: https://doi.org/10.1124/dmd.111.040972

  4. Iwai, Megumi

    1. Utility of P-Glycoprotein and Organic Cation Transporter 1 Double-Transfected LLC-PK1 Cells for Studying the Interaction of YM155 Monobromide, Novel Small-Molecule Survivin Suppressant, with P-Glycoprotein
      Megumi Iwai, Tsuyoshi Minematsu, Qun Li, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition December 2011, 39 (12) 2314-2320; DOI: https://doi.org/10.1124/dmd.111.040733

  5. Iwatsubo, Takafumi

    1. Utility of P-Glycoprotein and Organic Cation Transporter 1 Double-Transfected LLC-PK1 Cells for Studying the Interaction of YM155 Monobromide, Novel Small-Molecule Survivin Suppressant, with P-Glycoprotein
      Megumi Iwai, Tsuyoshi Minematsu, Qun Li, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition December 2011, 39 (12) 2314-2320; DOI: https://doi.org/10.1124/dmd.111.040733

J

  1. Jappar, Dilara

    1. Effect of Dose Escalation on the In Vivo Oral Absorption and Disposition of Glycylsarcosine in Wild-Type and Pept1 Knockout Mice
      Dilara Jappar, Yongjun Hu and David E. Smith
      Drug Metabolism and Disposition December 2011, 39 (12) 2250-2257; DOI: https://doi.org/10.1124/dmd.111.041087

  2. Jayaraman, Ramesh

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

  3. Jenkins, S. M.

    1. Studies to Further Investigate the Inhibition of Human Liver Microsomal CYP2C8 by the Acyl-β-Glucuronide of Gemfibrozil
      S. M. Jenkins, T. Zvyaga, S. R. Johnson, J. Hurley, A. Wagner, R. Burrell, W. Turley, J. E. Leet, T. Philip and A. D. Rodrigues
      Drug Metabolism and Disposition December 2011, 39 (12) 2421-2430; DOI: https://doi.org/10.1124/dmd.111.041947

  4. Jin, Lixia

    1. Effect of Culture Time on the Basal Expression Levels of Drug Transporters in Sandwich-Cultured Primary Rat Hepatocytes
      Eskouhie H. Tchaparian, Jessica S. Houghton, Craig Uyeda, Mark P. Grillo and Lixia Jin
      Drug Metabolism and Disposition December 2011, 39 (12) 2387-2394; DOI: https://doi.org/10.1124/dmd.111.039545

  5. Johnson, S. R.

    1. Studies to Further Investigate the Inhibition of Human Liver Microsomal CYP2C8 by the Acyl-β-Glucuronide of Gemfibrozil
      S. M. Jenkins, T. Zvyaga, S. R. Johnson, J. Hurley, A. Wagner, R. Burrell, W. Turley, J. E. Leet, T. Philip and A. D. Rodrigues
      Drug Metabolism and Disposition December 2011, 39 (12) 2421-2430; DOI: https://doi.org/10.1124/dmd.111.041947

  6. Jones, Jeffrey P.

    1. Inhibition of Human Liver Aldehyde Oxidase: Implications for Potential Drug-Drug Interactions
      John T. Barr and Jeffrey P. Jones
      Drug Metabolism and Disposition December 2011, 39 (12) 2381-2386; DOI: https://doi.org/10.1124/dmd.111.041806
    2. Small Molecule Quantification by Liquid Chromatography-Mass Spectrometry for Metabolites of Drugs and Drug Candidates
      Upendra P. Dahal, Jeffrey P. Jones, John A. Davis and Dan A. Rock
      Drug Metabolism and Disposition December 2011, 39 (12) 2355-2360; DOI: https://doi.org/10.1124/dmd.111.040865

  7. Juhl, Martin

    1. Biosynthesis and Identification of an N-Oxide/N-Glucuronide Metabolite and First Synthesis of an N-O-Glucuronide Metabolite of Lu AA21004
      Henriette Kold Uldam, Martin Juhl, Henrik Pedersen and Lars Dalgaard
      Drug Metabolism and Disposition December 2011, 39 (12) 2264-2274; DOI: https://doi.org/10.1124/dmd.111.040428

K

  1. Keinänen, Tuomo A.

    1. Complex N-Acetylation of Triethylenetetramine
      Marc Cerrada-Gimenez, Janne Weisell, Mervi T. Hyvönen, Myung Hee Park, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition December 2011, 39 (12) 2242-2249; DOI: https://doi.org/10.1124/dmd.111.041798

  2. Khalid Pasha, Mohammed

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

  3. Kharasch, Evan D.

    1. Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6, and 2C9 by Ritonavir or Nelfinavir
      Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj Desai, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2011, 39 (12) 2329-2337; DOI: https://doi.org/10.1124/dmd.111.038646

  4. Kirby, Brian J.

    1. Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6, and 2C9 by Ritonavir or Nelfinavir
      Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj Desai, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2011, 39 (12) 2329-2337; DOI: https://doi.org/10.1124/dmd.111.038646

  5. Kitamura, Yoshiaki

    1. Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4
      Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2361-2369; DOI: https://doi.org/10.1124/dmd.111.041814

  6. Klaubert, Dieter H.

    1. Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition
      Poncho L. Meisenheimer, H. Tetsuo Uyeda, Dongping Ma, Mary Sobol, Mark G. McDougall, Cesear Corona, Dan Simpson, Dieter H. Klaubert and James J. Cali
      Drug Metabolism and Disposition December 2011, 39 (12) 2403-2410; DOI: https://doi.org/10.1124/dmd.111.041541

  7. Kochanek, Patrick M.

    1. Cardiac Arrest and Therapeutic Hypothermia Decrease Isoform-Specific Cytochrome P450 Drug Metabolism
      Jiangquan Zhou, Philip E. Empey, Robert R. Bies, Patrick M. Kochanek and Samuel M. Poloyac
      Drug Metabolism and Disposition December 2011, 39 (12) 2209-2218; DOI: https://doi.org/10.1124/dmd.111.040642

  8. Koshimichi, Hiroki

    1. Analysis and Prediction of Drug Transfer into Human Milk Taking into Consideration Secretion and Reuptake Clearances across the Mammary Epithelia
      Hiroki Koshimichi, Kousei Ito, Akihiro Hisaka, Masashi Honma and Hiroshi Suzuki
      Drug Metabolism and Disposition December 2011, 39 (12) 2370-2380; DOI: https://doi.org/10.1124/dmd.111.040972

  9. Kusuhara, Hiroyuki

    1. Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4
      Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2361-2369; DOI: https://doi.org/10.1124/dmd.111.041814
    2. Involvement of Different Human Glutathione Transferase Isoforms in the Glutathione Conjugation of Reactive Metabolites of Troglitazone
      Ran Okada, Kazuya Maeda, Takahito Nishiyama, Shinsuke Aoyama, Zenzaburo Tozuka, Akira Hiratsuka, Toshihiko Ikeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2290-2297; DOI: https://doi.org/10.1124/dmd.111.040469

L

  1. Le, X. Chris

    1. Monomethylarsenic Diglutathione Transport by the Human Multidrug Resistance Protein 1 (MRP1/ABCC1)
      Michael W. Carew, Hua Naranmandura, Caley B. Shukalek, X. Chris Le and Elaine M. Leslie
      Drug Metabolism and Disposition December 2011, 39 (12) 2298-2304; DOI: https://doi.org/10.1124/dmd.111.041673

  2. Leet, J. E.

    1. Studies to Further Investigate the Inhibition of Human Liver Microsomal CYP2C8 by the Acyl-β-Glucuronide of Gemfibrozil
      S. M. Jenkins, T. Zvyaga, S. R. Johnson, J. Hurley, A. Wagner, R. Burrell, W. Turley, J. E. Leet, T. Philip and A. D. Rodrigues
      Drug Metabolism and Disposition December 2011, 39 (12) 2421-2430; DOI: https://doi.org/10.1124/dmd.111.041947

  3. Leslie, Elaine M.

    1. Monomethylarsenic Diglutathione Transport by the Human Multidrug Resistance Protein 1 (MRP1/ABCC1)
      Michael W. Carew, Hua Naranmandura, Caley B. Shukalek, X. Chris Le and Elaine M. Leslie
      Drug Metabolism and Disposition December 2011, 39 (12) 2298-2304; DOI: https://doi.org/10.1124/dmd.111.041673

  4. Li, Qun

    1. Utility of P-Glycoprotein and Organic Cation Transporter 1 Double-Transfected LLC-PK1 Cells for Studying the Interaction of YM155 Monobromide, Novel Small-Molecule Survivin Suppressant, with P-Glycoprotein
      Megumi Iwai, Tsuyoshi Minematsu, Qun Li, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition December 2011, 39 (12) 2314-2320; DOI: https://doi.org/10.1124/dmd.111.040733

  5. Lin, Hsia-lien

    1. Thr302 Is the Site for the Covalent Modification of Human Cytochrome P450 2B6 Leading to Mechanism-Based Inactivation by tert-Butylphenylacetylene
      Hsia-lien Lin, Haoming Zhang, Matthew J. Pratt-Hyatt and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2011, 39 (12) 2431-2439; DOI: https://doi.org/10.1124/dmd.111.042176

  6. Lowinger, Jennifer J.

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

  7. Lundqvist, Anders J.

    1. Development of a Highly Sensitive Method Using Liquid Chromatography-Multiple Reaction Monitoring to Quantify Membrane P-Glycoprotein in Biological Matrices and Relationship to Transport Function
      Tasso Miliotis, Liaqat Ali, Johan E. Palm, Anders J. Lundqvist, Martin Ahnoff, Tommy B. Andersson and Constanze Hilgendorf
      Drug Metabolism and Disposition December 2011, 39 (12) 2440-2449; DOI: https://doi.org/10.1124/dmd.111.040774

M

  1. Ma, Dongping

    1. Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition
      Poncho L. Meisenheimer, H. Tetsuo Uyeda, Dongping Ma, Mary Sobol, Mark G. McDougall, Cesear Corona, Dan Simpson, Dieter H. Klaubert and James J. Cali
      Drug Metabolism and Disposition December 2011, 39 (12) 2403-2410; DOI: https://doi.org/10.1124/dmd.111.041541

  2. Maeda, Kazuya

    1. Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4
      Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2361-2369; DOI: https://doi.org/10.1124/dmd.111.041814
    2. Involvement of Different Human Glutathione Transferase Isoforms in the Glutathione Conjugation of Reactive Metabolites of Troglitazone
      Ran Okada, Kazuya Maeda, Takahito Nishiyama, Shinsuke Aoyama, Zenzaburo Tozuka, Akira Hiratsuka, Toshihiko Ikeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2290-2297; DOI: https://doi.org/10.1124/dmd.111.040469

  3. McDougall, Mark G.

    1. Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition
      Poncho L. Meisenheimer, H. Tetsuo Uyeda, Dongping Ma, Mary Sobol, Mark G. McDougall, Cesear Corona, Dan Simpson, Dieter H. Klaubert and James J. Cali
      Drug Metabolism and Disposition December 2011, 39 (12) 2403-2410; DOI: https://doi.org/10.1124/dmd.111.041541

  4. Meisenheimer, Poncho L.

    1. Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition
      Poncho L. Meisenheimer, H. Tetsuo Uyeda, Dongping Ma, Mary Sobol, Mark G. McDougall, Cesear Corona, Dan Simpson, Dieter H. Klaubert and James J. Cali
      Drug Metabolism and Disposition December 2011, 39 (12) 2403-2410; DOI: https://doi.org/10.1124/dmd.111.041541

  5. Meyer, Achim

    1. CYP2C19 Progress Curve Analysis and Mechanism-Based Inactivation by Three Methylenedioxyphenyl Compounds
      Kaisa A. Salminen, Achim Meyer, Peter Imming and Hannu Raunio
      Drug Metabolism and Disposition December 2011, 39 (12) 2283-2289; DOI: https://doi.org/10.1124/dmd.111.041319

  6. Meyers, Catherine M.

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

  7. Miao, Zhuang

    1. Excretion, Metabolism, and Pharmacokinetics of CP-945,598, a Selective Cannabinoid Receptor Antagonist, in Rats, Mice, and Dogs
      Zhuang Miao, Dennis O. Scott, David A. Griffith, Robert Day and Chandra Prakash
      Drug Metabolism and Disposition December 2011, 39 (12) 2191-2208; DOI: https://doi.org/10.1124/dmd.111.040360

  8. Miksys, S.

    1. Independent and Combined Effects of Ethanol Self-Administration and Nicotine Treatment on Hepatic CYP2E1 in African Green Monkeys
      C. S. Ferguson, S. Miksys, R. Palmour and R. F. Tyndale
      Drug Metabolism and Disposition December 2011, 39 (12) 2233-2241; DOI: https://doi.org/10.1124/dmd.111.040378

  9. Miliotis, Tasso

    1. Development of a Highly Sensitive Method Using Liquid Chromatography-Multiple Reaction Monitoring to Quantify Membrane P-Glycoprotein in Biological Matrices and Relationship to Transport Function
      Tasso Miliotis, Liaqat Ali, Johan E. Palm, Anders J. Lundqvist, Martin Ahnoff, Tommy B. Andersson and Constanze Hilgendorf
      Drug Metabolism and Disposition December 2011, 39 (12) 2440-2449; DOI: https://doi.org/10.1124/dmd.111.040774

  10. Milne, Alison M.

    1. A Novel Method for the Immunoquantification of UDP-Glucuronosyltransferases in Human Tissue
      Alison M. Milne, Brian Burchell and Michael W. H. Coughtrie
      Drug Metabolism and Disposition December 2011, 39 (12) 2258-2263; DOI: https://doi.org/10.1124/dmd.111.041699

  11. Minematsu, Tsuyoshi

    1. Utility of P-Glycoprotein and Organic Cation Transporter 1 Double-Transfected LLC-PK1 Cells for Studying the Interaction of YM155 Monobromide, Novel Small-Molecule Survivin Suppressant, with P-Glycoprotein
      Megumi Iwai, Tsuyoshi Minematsu, Qun Li, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition December 2011, 39 (12) 2314-2320; DOI: https://doi.org/10.1124/dmd.111.040733

  12. Mrhar, Aleš

    1. Raloxifene Glucuronidation in Human Intestine, Kidney, and Liver Microsomes and in Human Liver Microsomes Genotyped for the UGT1A1*28 Polymorphism
      Tina Trdan Lušin, Jurij Trontelj and Aleš Mrhar
      Drug Metabolism and Disposition December 2011, 39 (12) 2347-2354; DOI: https://doi.org/10.1124/dmd.111.041897

N

  1. Naranmandura, Hua

    1. Monomethylarsenic Diglutathione Transport by the Human Multidrug Resistance Protein 1 (MRP1/ABCC1)
      Michael W. Carew, Hua Naranmandura, Caley B. Shukalek, X. Chris Le and Elaine M. Leslie
      Drug Metabolism and Disposition December 2011, 39 (12) 2298-2304; DOI: https://doi.org/10.1124/dmd.111.041673

  2. Navarro, Victor J.

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

  3. Nishiyama, Takahito

    1. Involvement of Different Human Glutathione Transferase Isoforms in the Glutathione Conjugation of Reactive Metabolites of Troglitazone
      Ran Okada, Kazuya Maeda, Takahito Nishiyama, Shinsuke Aoyama, Zenzaburo Tozuka, Akira Hiratsuka, Toshihiko Ikeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2290-2297; DOI: https://doi.org/10.1124/dmd.111.040469

O

  1. O'Reilly, D. A.

    1. Intestinal Ciprofloxacin Efflux: The Role of Breast Cancer Resistance Protein (ABCG2)
      I. S. Haslam, J. A. Wright, D. A. O'Reilly, D. J. Sherlock, T. Coleman and N. L. Simmons
      Drug Metabolism and Disposition December 2011, 39 (12) 2321-2328; DOI: https://doi.org/10.1124/dmd.111.038323

  2. Okada, Ran

    1. Involvement of Different Human Glutathione Transferase Isoforms in the Glutathione Conjugation of Reactive Metabolites of Troglitazone
      Ran Okada, Kazuya Maeda, Takahito Nishiyama, Shinsuke Aoyama, Zenzaburo Tozuka, Akira Hiratsuka, Toshihiko Ikeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2290-2297; DOI: https://doi.org/10.1124/dmd.111.040469

P

  1. Palm, Johan E.

    1. Development of a Highly Sensitive Method Using Liquid Chromatography-Multiple Reaction Monitoring to Quantify Membrane P-Glycoprotein in Biological Matrices and Relationship to Transport Function
      Tasso Miliotis, Liaqat Ali, Johan E. Palm, Anders J. Lundqvist, Martin Ahnoff, Tommy B. Andersson and Constanze Hilgendorf
      Drug Metabolism and Disposition December 2011, 39 (12) 2440-2449; DOI: https://doi.org/10.1124/dmd.111.040774

  2. Palmour, R.

    1. Independent and Combined Effects of Ethanol Self-Administration and Nicotine Treatment on Hepatic CYP2E1 in African Green Monkeys
      C. S. Ferguson, S. Miksys, R. Palmour and R. F. Tyndale
      Drug Metabolism and Disposition December 2011, 39 (12) 2233-2241; DOI: https://doi.org/10.1124/dmd.111.040378

  3. Pedersen, Henrik

    1. Biosynthesis and Identification of an N-Oxide/N-Glucuronide Metabolite and First Synthesis of an N-O-Glucuronide Metabolite of Lu AA21004
      Henriette Kold Uldam, Martin Juhl, Henrik Pedersen and Lars Dalgaard
      Drug Metabolism and Disposition December 2011, 39 (12) 2264-2274; DOI: https://doi.org/10.1124/dmd.111.040428

  4. Perkins, Everett J.

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

  5. Philip, T.

    1. Studies to Further Investigate the Inhibition of Human Liver Microsomal CYP2C8 by the Acyl-β-Glucuronide of Gemfibrozil
      S. M. Jenkins, T. Zvyaga, S. R. Johnson, J. Hurley, A. Wagner, R. Burrell, W. Turley, J. E. Leet, T. Philip and A. D. Rodrigues
      Drug Metabolism and Disposition December 2011, 39 (12) 2421-2430; DOI: https://doi.org/10.1124/dmd.111.041947

  6. Phillips, David H.

    1. Effect of Hepatic Cytochrome P450 (P450) Oxidoreductase Deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 Reductase Conditional Null Mice
      Volker M. Arlt, Rajinder Singh, Marie Stiborová, Gonçalo Gamboa da Costa, Eva Frei, James D. Evans, Peter B. Farmer, C. Roland Wolf, Colin J. Henderson and David H. Phillips
      Drug Metabolism and Disposition December 2011, 39 (12) 2169-2173; DOI: https://doi.org/10.1124/dmd.111.041343

  7. Pilla Reddy, Venkatesh

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

  8. Ploeger, Bart A.

    1. Systemic and Direct Nose-to-Brain Transport Pharmacokinetic Model for Remoxipride after Intravenous and Intranasal Administration
      Jasper Stevens, Bart A. Ploeger, Piet H. van der Graaf, Meindert Danhof and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition December 2011, 39 (12) 2275-2282; DOI: https://doi.org/10.1124/dmd.111.040782

  9. Poloyac, Samuel M.

    1. Cardiac Arrest and Therapeutic Hypothermia Decrease Isoform-Specific Cytochrome P450 Drug Metabolism
      Jiangquan Zhou, Philip E. Empey, Robert R. Bies, Patrick M. Kochanek and Samuel M. Poloyac
      Drug Metabolism and Disposition December 2011, 39 (12) 2209-2218; DOI: https://doi.org/10.1124/dmd.111.040642

  10. Poquet, Laure

    1. Absorption and Metabolism of Chlorogenic Acids in Cultured Gastric Epithelial Monolayers
      Tracy L. Farrell, Tristan P. Dew, Laure Poquet, Peter Hanson and Gary Williamson
      Drug Metabolism and Disposition December 2011, 39 (12) 2338-2346; DOI: https://doi.org/10.1124/dmd.111.040147

  11. Prakash, Chandra

    1. Excretion, Metabolism, and Pharmacokinetics of CP-945,598, a Selective Cannabinoid Receptor Antagonist, in Rats, Mice, and Dogs
      Zhuang Miao, Dennis O. Scott, David A. Griffith, Robert Day and Chandra Prakash
      Drug Metabolism and Disposition December 2011, 39 (12) 2191-2208; DOI: https://doi.org/10.1124/dmd.111.040360

  12. Pratt-Hyatt, Matthew J.

    1. Thr302 Is the Site for the Covalent Modification of Human Cytochrome P450 2B6 Leading to Mechanism-Based Inactivation by tert-Butylphenylacetylene
      Hsia-lien Lin, Haoming Zhang, Matthew J. Pratt-Hyatt and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2011, 39 (12) 2431-2439; DOI: https://doi.org/10.1124/dmd.111.042176

Q

  1. Qian, Yue-Wei

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

R

  1. Raunio, Hannu

    1. CYP2C19 Progress Curve Analysis and Mechanism-Based Inactivation by Three Methylenedioxyphenyl Compounds
      Kaisa A. Salminen, Achim Meyer, Peter Imming and Hannu Raunio
      Drug Metabolism and Disposition December 2011, 39 (12) 2283-2289; DOI: https://doi.org/10.1124/dmd.111.041319

  2. Rea, Vanina

    1. Role of Residue 87 in the Activity and Regioselectivity of Clozapine Metabolism by Drug-Metabolizing CYP102A1 M11H: Application for Structural Characterization of Clozapine GSH Conjugates
      Vanina Rea, Sanja Dragovic, Jan Simon Boerma, Frans J. J. de Kanter, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition December 2011, 39 (12) 2411-2420; DOI: https://doi.org/10.1124/dmd.111.041046

  3. Reddy, K. Rajender

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

  4. Riley, Rob J.

    1. Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4
      Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2361-2369; DOI: https://doi.org/10.1124/dmd.111.041814

  5. Rock, Dan A.

    1. Small Molecule Quantification by Liquid Chromatography-Mass Spectrometry for Metabolites of Drugs and Drug Candidates
      Upendra P. Dahal, Jeffrey P. Jones, John A. Davis and Dan A. Rock
      Drug Metabolism and Disposition December 2011, 39 (12) 2355-2360; DOI: https://doi.org/10.1124/dmd.111.040865

  6. Rodrigues, A. D.

    1. Studies to Further Investigate the Inhibition of Human Liver Microsomal CYP2C8 by the Acyl-β-Glucuronide of Gemfibrozil
      S. M. Jenkins, T. Zvyaga, S. R. Johnson, J. Hurley, A. Wagner, R. Burrell, W. Turley, J. E. Leet, T. Philip and A. D. Rodrigues
      Drug Metabolism and Disposition December 2011, 39 (12) 2421-2430; DOI: https://doi.org/10.1124/dmd.111.041947

  7. Rowland, Malcolm

    1. Correction for Nonspecific Binding to Various Components of Ultrafiltration Apparatus and Impact on Estimating In Vivo Rat Clearance for a Congeneric Series of 5-Ethyl, 5-n-Alkyl Barbituric Acids
      Peter Ballard and Malcolm Rowland
      Drug Metabolism and Disposition December 2011, 39 (12) 2165-2168; DOI: https://doi.org/10.1124/dmd.111.040683

  8. Ruterbories, Kenneth J.

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

S

  1. Salminen, Kaisa A.

    1. CYP2C19 Progress Curve Analysis and Mechanism-Based Inactivation by Three Methylenedioxyphenyl Compounds
      Kaisa A. Salminen, Achim Meyer, Peter Imming and Hannu Raunio
      Drug Metabolism and Disposition December 2011, 39 (12) 2283-2289; DOI: https://doi.org/10.1124/dmd.111.041319

  2. Sangthongpitag, Kanda

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

  3. Scheffer, George L.

    1. Variations in ATP-Binding Cassette Transporter Regulation during the Progression of Human Nonalcoholic Fatty Liver Disease
      Rhiannon N. Hardwick, Craig D. Fisher, Mark J. Canet, George L. Scheffer and Nathan J. Cherrington
      Drug Metabolism and Disposition December 2011, 39 (12) 2395-2402; DOI: https://doi.org/10.1124/dmd.111.041012

  4. Schmitt, Ellen I.

    1. Production of Ibuprofen Acyl Glucosides by Human UGT2B7
      Daniela Buchheit, Călin-Aurel Drăgan, Ellen I. Schmitt and Matthias Bureik
      Drug Metabolism and Disposition December 2011, 39 (12) 2174-2181; DOI: https://doi.org/10.1124/dmd.111.041640

  5. Schrieber, Sarah J.

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

  6. Scott, Dennis O.

    1. Excretion, Metabolism, and Pharmacokinetics of CP-945,598, a Selective Cannabinoid Receptor Antagonist, in Rats, Mice, and Dogs
      Zhuang Miao, Dennis O. Scott, David A. Griffith, Robert Day and Chandra Prakash
      Drug Metabolism and Disposition December 2011, 39 (12) 2191-2208; DOI: https://doi.org/10.1124/dmd.111.040360

  7. Sherlock, D. J.

    1. Intestinal Ciprofloxacin Efflux: The Role of Breast Cancer Resistance Protein (ABCG2)
      I. S. Haslam, J. A. Wright, D. A. O'Reilly, D. J. Sherlock, T. Coleman and N. L. Simmons
      Drug Metabolism and Disposition December 2011, 39 (12) 2321-2328; DOI: https://doi.org/10.1124/dmd.111.038323

  8. Shukalek, Caley B.

    1. Monomethylarsenic Diglutathione Transport by the Human Multidrug Resistance Protein 1 (MRP1/ABCC1)
      Michael W. Carew, Hua Naranmandura, Caley B. Shukalek, X. Chris Le and Elaine M. Leslie
      Drug Metabolism and Disposition December 2011, 39 (12) 2298-2304; DOI: https://doi.org/10.1124/dmd.111.041673

  9. Simmons, N. L.

    1. Intestinal Ciprofloxacin Efflux: The Role of Breast Cancer Resistance Protein (ABCG2)
      I. S. Haslam, J. A. Wright, D. A. O'Reilly, D. J. Sherlock, T. Coleman and N. L. Simmons
      Drug Metabolism and Disposition December 2011, 39 (12) 2321-2328; DOI: https://doi.org/10.1124/dmd.111.038323

  10. Simpson, Dan

    1. Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition
      Poncho L. Meisenheimer, H. Tetsuo Uyeda, Dongping Ma, Mary Sobol, Mark G. McDougall, Cesear Corona, Dan Simpson, Dieter H. Klaubert and James J. Cali
      Drug Metabolism and Disposition December 2011, 39 (12) 2403-2410; DOI: https://doi.org/10.1124/dmd.111.041541

  11. Singh, Rajinder

    1. Effect of Hepatic Cytochrome P450 (P450) Oxidoreductase Deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 Reductase Conditional Null Mice
      Volker M. Arlt, Rajinder Singh, Marie Stiborová, Gonçalo Gamboa da Costa, Eva Frei, James D. Evans, Peter B. Farmer, C. Roland Wolf, Colin J. Henderson and David H. Phillips
      Drug Metabolism and Disposition December 2011, 39 (12) 2169-2173; DOI: https://doi.org/10.1124/dmd.111.041343

  12. Smith, David E.

    1. Effect of Dose Escalation on the In Vivo Oral Absorption and Disposition of Glycylsarcosine in Wild-Type and Pept1 Knockout Mice
      Dilara Jappar, Yongjun Hu and David E. Smith
      Drug Metabolism and Disposition December 2011, 39 (12) 2250-2257; DOI: https://doi.org/10.1124/dmd.111.041087

  13. Smith, Philip C.

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

  14. Sobol, Mary

    1. Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition
      Poncho L. Meisenheimer, H. Tetsuo Uyeda, Dongping Ma, Mary Sobol, Mark G. McDougall, Cesear Corona, Dan Simpson, Dieter H. Klaubert and James J. Cali
      Drug Metabolism and Disposition December 2011, 39 (12) 2403-2410; DOI: https://doi.org/10.1124/dmd.111.041541

  15. Stevens, Jasper

    1. Systemic and Direct Nose-to-Brain Transport Pharmacokinetic Model for Remoxipride after Intravenous and Intranasal Administration
      Jasper Stevens, Bart A. Ploeger, Piet H. van der Graaf, Meindert Danhof and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition December 2011, 39 (12) 2275-2282; DOI: https://doi.org/10.1124/dmd.111.040782

  16. Stiborová, Marie

    1. Effect of Hepatic Cytochrome P450 (P450) Oxidoreductase Deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 Reductase Conditional Null Mice
      Volker M. Arlt, Rajinder Singh, Marie Stiborová, Gonçalo Gamboa da Costa, Eva Frei, James D. Evans, Peter B. Farmer, C. Roland Wolf, Colin J. Henderson and David H. Phillips
      Drug Metabolism and Disposition December 2011, 39 (12) 2169-2173; DOI: https://doi.org/10.1124/dmd.111.041343

  17. Sugiyama, Yuichi

    1. Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4
      Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2361-2369; DOI: https://doi.org/10.1124/dmd.111.041814
    2. Involvement of Different Human Glutathione Transferase Isoforms in the Glutathione Conjugation of Reactive Metabolites of Troglitazone
      Ran Okada, Kazuya Maeda, Takahito Nishiyama, Shinsuke Aoyama, Zenzaburo Tozuka, Akira Hiratsuka, Toshihiko Ikeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2290-2297; DOI: https://doi.org/10.1124/dmd.111.040469

  18. Sun New, Lee

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

  19. Suzuki, Hiroshi

    1. Analysis and Prediction of Drug Transfer into Human Milk Taking into Consideration Secretion and Reuptake Clearances across the Mammary Epithelia
      Hiroki Koshimichi, Kousei Ito, Akihiro Hisaka, Masashi Honma and Hiroshi Suzuki
      Drug Metabolism and Disposition December 2011, 39 (12) 2370-2380; DOI: https://doi.org/10.1124/dmd.111.040972

T

  1. Tchaparian, Eskouhie H.

    1. Effect of Culture Time on the Basal Expression Levels of Drug Transporters in Sandwich-Cultured Primary Rat Hepatocytes
      Eskouhie H. Tchaparian, Jessica S. Houghton, Craig Uyeda, Mark P. Grillo and Lixia Jin
      Drug Metabolism and Disposition December 2011, 39 (12) 2387-2394; DOI: https://doi.org/10.1124/dmd.111.039545

  2. Thummel, Kenneth E.

    1. Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6, and 2C9 by Ritonavir or Nelfinavir
      Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj Desai, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2011, 39 (12) 2329-2337; DOI: https://doi.org/10.1124/dmd.111.038646

  3. Tozuka, Zenzaburo

    1. Involvement of Different Human Glutathione Transferase Isoforms in the Glutathione Conjugation of Reactive Metabolites of Troglitazone
      Ran Okada, Kazuya Maeda, Takahito Nishiyama, Shinsuke Aoyama, Zenzaburo Tozuka, Akira Hiratsuka, Toshihiko Ikeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2290-2297; DOI: https://doi.org/10.1124/dmd.111.040469

  4. Trdan Lušin, Tina

    1. Raloxifene Glucuronidation in Human Intestine, Kidney, and Liver Microsomes and in Human Liver Microsomes Genotyped for the UGT1A1*28 Polymorphism
      Tina Trdan Lušin, Jurij Trontelj and Aleš Mrhar
      Drug Metabolism and Disposition December 2011, 39 (12) 2347-2354; DOI: https://doi.org/10.1124/dmd.111.041897

  5. Trontelj, Jurij

    1. Raloxifene Glucuronidation in Human Intestine, Kidney, and Liver Microsomes and in Human Liver Microsomes Genotyped for the UGT1A1*28 Polymorphism
      Tina Trdan Lušin, Jurij Trontelj and Aleš Mrhar
      Drug Metabolism and Disposition December 2011, 39 (12) 2347-2354; DOI: https://doi.org/10.1124/dmd.111.041897

  6. Turley, W.

    1. Studies to Further Investigate the Inhibition of Human Liver Microsomal CYP2C8 by the Acyl-β-Glucuronide of Gemfibrozil
      S. M. Jenkins, T. Zvyaga, S. R. Johnson, J. Hurley, A. Wagner, R. Burrell, W. Turley, J. E. Leet, T. Philip and A. D. Rodrigues
      Drug Metabolism and Disposition December 2011, 39 (12) 2421-2430; DOI: https://doi.org/10.1124/dmd.111.041947

  7. Tyndale, R. F.

    1. Independent and Combined Effects of Ethanol Self-Administration and Nicotine Treatment on Hepatic CYP2E1 in African Green Monkeys
      C. S. Ferguson, S. Miksys, R. Palmour and R. F. Tyndale
      Drug Metabolism and Disposition December 2011, 39 (12) 2233-2241; DOI: https://doi.org/10.1124/dmd.111.040378

U

  1. Uldam, Henriette Kold

    1. Biosynthesis and Identification of an N-Oxide/N-Glucuronide Metabolite and First Synthesis of an N-O-Glucuronide Metabolite of Lu AA21004
      Henriette Kold Uldam, Martin Juhl, Henrik Pedersen and Lars Dalgaard
      Drug Metabolism and Disposition December 2011, 39 (12) 2264-2274; DOI: https://doi.org/10.1124/dmd.111.040428

  2. Unadkat, Jashvant D.

    1. Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6, and 2C9 by Ritonavir or Nelfinavir
      Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj Desai, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2011, 39 (12) 2329-2337; DOI: https://doi.org/10.1124/dmd.111.038646

  3. Usui, Takashi

    1. Utility of P-Glycoprotein and Organic Cation Transporter 1 Double-Transfected LLC-PK1 Cells for Studying the Interaction of YM155 Monobromide, Novel Small-Molecule Survivin Suppressant, with P-Glycoprotein
      Megumi Iwai, Tsuyoshi Minematsu, Qun Li, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition December 2011, 39 (12) 2314-2320; DOI: https://doi.org/10.1124/dmd.111.040733

  4. Uyeda, Craig

    1. Effect of Culture Time on the Basal Expression Levels of Drug Transporters in Sandwich-Cultured Primary Rat Hepatocytes
      Eskouhie H. Tchaparian, Jessica S. Houghton, Craig Uyeda, Mark P. Grillo and Lixia Jin
      Drug Metabolism and Disposition December 2011, 39 (12) 2387-2394; DOI: https://doi.org/10.1124/dmd.111.039545

  5. Uyeda, H. Tetsuo

    1. Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition
      Poncho L. Meisenheimer, H. Tetsuo Uyeda, Dongping Ma, Mary Sobol, Mark G. McDougall, Cesear Corona, Dan Simpson, Dieter H. Klaubert and James J. Cali
      Drug Metabolism and Disposition December 2011, 39 (12) 2403-2410; DOI: https://doi.org/10.1124/dmd.111.041541

V

  1. van der Graaf, Piet H.

    1. Systemic and Direct Nose-to-Brain Transport Pharmacokinetic Model for Remoxipride after Intravenous and Intranasal Administration
      Jasper Stevens, Bart A. Ploeger, Piet H. van der Graaf, Meindert Danhof and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition December 2011, 39 (12) 2275-2282; DOI: https://doi.org/10.1124/dmd.111.040782

  2. Vepsäläinen, Jouko

    1. Complex N-Acetylation of Triethylenetetramine
      Marc Cerrada-Gimenez, Janne Weisell, Mervi T. Hyvönen, Myung Hee Park, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition December 2011, 39 (12) 2242-2249; DOI: https://doi.org/10.1124/dmd.111.041798

  3. Vermeulen, Nico P. E.

    1. Role of Residue 87 in the Activity and Regioselectivity of Clozapine Metabolism by Drug-Metabolizing CYP102A1 M11H: Application for Structural Characterization of Clozapine GSH Conjugates
      Vanina Rea, Sanja Dragovic, Jan Simon Boerma, Frans J. J. de Kanter, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition December 2011, 39 (12) 2411-2420; DOI: https://doi.org/10.1124/dmd.111.041046

W

  1. Wagner, A.

    1. Studies to Further Investigate the Inhibition of Human Liver Microsomal CYP2C8 by the Acyl-β-Glucuronide of Gemfibrozil
      S. M. Jenkins, T. Zvyaga, S. R. Johnson, J. Hurley, A. Wagner, R. Burrell, W. Turley, J. E. Leet, T. Philip and A. D. Rodrigues
      Drug Metabolism and Disposition December 2011, 39 (12) 2421-2430; DOI: https://doi.org/10.1124/dmd.111.041947

  2. Wahed, Abdus S.

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

  3. Wang, Haishan

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

  4. Wang, He

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

  5. Wang, Xiliang

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

  6. Webborn, Peter J. H.

    1. Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4
      Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2361-2369; DOI: https://doi.org/10.1124/dmd.111.041814

  7. Weisell, Janne

    1. Complex N-Acetylation of Triethylenetetramine
      Marc Cerrada-Gimenez, Janne Weisell, Mervi T. Hyvönen, Myung Hee Park, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition December 2011, 39 (12) 2242-2249; DOI: https://doi.org/10.1124/dmd.111.041798

  8. Wen, Zhiming

    1. Differences in the Disposition of Silymarin between Patients with Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
      Sarah J. Schrieber, Roy L. Hawke, Zhiming Wen, Philip C. Smith, K. Rajender Reddy, Abdus S. Wahed, Steven H. Belle, Nezam H. Afdhal, Victor J. Navarro, Catherine M. Meyers, Edward Doo and Michael. W. Fried
      Drug Metabolism and Disposition December 2011, 39 (12) 2182-2190; DOI: https://doi.org/10.1124/dmd.111.040212

  9. Whittington, Dale

    1. Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6, and 2C9 by Ritonavir or Nelfinavir
      Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj Desai, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2011, 39 (12) 2329-2337; DOI: https://doi.org/10.1124/dmd.111.038646

  10. Wilby, Alison J.

    1. Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4
      Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2011, 39 (12) 2361-2369; DOI: https://doi.org/10.1124/dmd.111.041814

  11. Williams, Eric T.

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

  12. Williamson, Gary

    1. Absorption and Metabolism of Chlorogenic Acids in Cultured Gastric Epithelial Monolayers
      Tracy L. Farrell, Tristan P. Dew, Laure Poquet, Peter Hanson and Gary Williamson
      Drug Metabolism and Disposition December 2011, 39 (12) 2338-2346; DOI: https://doi.org/10.1124/dmd.111.040147

  13. Wolf, C. Roland

    1. Effect of Hepatic Cytochrome P450 (P450) Oxidoreductase Deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 Reductase Conditional Null Mice
      Volker M. Arlt, Rajinder Singh, Marie Stiborová, Gonçalo Gamboa da Costa, Eva Frei, James D. Evans, Peter B. Farmer, C. Roland Wolf, Colin J. Henderson and David H. Phillips
      Drug Metabolism and Disposition December 2011, 39 (12) 2169-2173; DOI: https://doi.org/10.1124/dmd.111.041343

  14. Wright, J. A.

    1. Intestinal Ciprofloxacin Efflux: The Role of Breast Cancer Resistance Protein (ABCG2)
      I. S. Haslam, J. A. Wright, D. A. O'Reilly, D. J. Sherlock, T. Coleman and N. L. Simmons
      Drug Metabolism and Disposition December 2011, 39 (12) 2321-2328; DOI: https://doi.org/10.1124/dmd.111.038323

  15. Wrighton, Steven A.

    1. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
      Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wen-Kai Guo, Mariam E. Ehsani, Xiliang Wang, He Wang, Yue-Wei Qian, Kenneth J. Ruterbories, Steven A. Wrighton and Everett J. Perkins
      Drug Metabolism and Disposition December 2011, 39 (12) 2305-2313; DOI: https://doi.org/10.1124/dmd.111.041335

  16. Wu, Xiaofeng

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

X

  1. Xin, Liu

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

Y

  1. Yeo, Pauline

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

  2. Yong Hu, Chang

    1. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
      Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Liu Xin, Evelyn Goh, Lee Sun New and Kantharaj Ethirajulu
      Drug Metabolism and Disposition December 2011, 39 (12) 2219-2232; DOI: https://doi.org/10.1124/dmd.111.041558

Z

  1. Zhang, Haoming

    1. Thr302 Is the Site for the Covalent Modification of Human Cytochrome P450 2B6 Leading to Mechanism-Based Inactivation by tert-Butylphenylacetylene
      Hsia-lien Lin, Haoming Zhang, Matthew J. Pratt-Hyatt and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2011, 39 (12) 2431-2439; DOI: https://doi.org/10.1124/dmd.111.042176

  2. Zhou, Jiangquan

    1. Cardiac Arrest and Therapeutic Hypothermia Decrease Isoform-Specific Cytochrome P450 Drug Metabolism
      Jiangquan Zhou, Philip E. Empey, Robert R. Bies, Patrick M. Kochanek and Samuel M. Poloyac
      Drug Metabolism and Disposition December 2011, 39 (12) 2209-2218; DOI: https://doi.org/10.1124/dmd.111.040642

  3. Zvyaga, T.

    1. Studies to Further Investigate the Inhibition of Human Liver Microsomal CYP2C8 by the Acyl-β-Glucuronide of Gemfibrozil
      S. M. Jenkins, T. Zvyaga, S. R. Johnson, J. Hurley, A. Wagner, R. Burrell, W. Turley, J. E. Leet, T. Philip and A. D. Rodrigues
      Drug Metabolism and Disposition December 2011, 39 (12) 2421-2430; DOI: https://doi.org/10.1124/dmd.111.041947
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