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Research ArticleArticle

Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6, and 2C9 by Ritonavir or Nelfinavir

Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj Desai, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
Drug Metabolism and Disposition December 2011, 39 (12) 2329-2337; DOI: https://doi.org/10.1124/dmd.111.038646
Brian J. Kirby
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Ann C. Collier
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Evan D. Kharasch
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Vaishali Dixit
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Pankaj Desai
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Dale Whittington
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Kenneth E. Thummel
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Jashvant D. Unadkat
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Article Information

vol. 39 no. 12 2329-2337
DOI 
https://doi.org/10.1124/dmd.111.038646
PubMed 
21930825

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 8, 2011
  • Accepted September 6, 2011
  • Published online November 21, 2011.

Article Versions

  • Earlier version (September 19, 2011 - 10:35).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Brian J. Kirby,
  2. Ann C. Collier,
  3. Evan D. Kharasch,
  4. Vaishali Dixit,
  5. Pankaj Desai,
  6. Dale Whittington,
  7. Kenneth E. Thummel and
  8. Jashvant D. Unadkat
  1. Departments of Pharmaceutics (B.J.K., V.D., D.W., K.E.T., J.D.U.) and Medicine (A.C.C.), University of Washington, Seattle, Washington; Department of Anesthesiology, Washington University, St. Louis, Missouri (E.D.K.); and Department of Pharmacokinetics and Biopharmaceutics, University of Cincinnati Medical Center, Cincinnati, Ohio (P.D.)
  1. Address correspondence to:
    Jashvant D. Unadkat, Department of Pharmaceutics, School of Pharmacy, Box 357610, University of Washington, Seattle, WA 98195-7610. E-mail: jash{at}u.washington.edu
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Drug Metabolism and Disposition: 39 (12)
Drug Metabolism and Disposition
Vol. 39, Issue 12
1 Dec 2011
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Research ArticleArticle

RITONAVIR, NELFINAVIR, OR RIFAMPIN CYTOCHROME P450 INDUCTION

Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj Desai, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
Drug Metabolism and Disposition December 1, 2011, 39 (12) 2329-2337; DOI: https://doi.org/10.1124/dmd.111.038646

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Research ArticleArticle

RITONAVIR, NELFINAVIR, OR RIFAMPIN CYTOCHROME P450 INDUCTION

Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj Desai, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
Drug Metabolism and Disposition December 1, 2011, 39 (12) 2329-2337; DOI: https://doi.org/10.1124/dmd.111.038646
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