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Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4

Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley and Yuichi Sugiyama
Drug Metabolism and Disposition December 2011, 39 (12) 2361-2369; DOI: https://doi.org/10.1124/dmd.111.041814

Article Information

vol. 39 no. 12 2361-2369
DOI 
https://doi.org/10.1124/dmd.111.041814
PubMed 
21940906
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received July 15, 2011
  • Accepted September 22, 2011
  • Published online November 21, 2011.

Article Versions

Copyright & Usage 
Copyright © 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Alison J. Wilby,
  2. Kazuya Maeda,
  3. Paul F. Courtney,
  4. Yasuyuki Debori,
  5. Peter J. H. Webborn,
  6. Yoshiaki Kitamura,
  7. Hiroyuki Kusuhara,
  8. Rob J. Riley and
  9. Yuichi Sugiyama
  1. Department of Discovery DMPK, AstraZeneca R&D Charnwood, Loughborough, United Kingdom (A.J.W., P.F.C., P.J.H.W., R.J.R.); and Department of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (K.M., Y.D., Y.K., H.K., Y.S.)
  1. Address correspondence to:
    Dr. Alison J Wilby, DMPK Group, Evotec (UK) Ltd., 114 Milton Park, Abingdon, Oxon, OX14 4SA, UK. E-mail: alison.wilby{at}evotec.com
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UPTAKE IN DOG HEPATOCYTES AND Oatp1b4-EXPRESSING CELLS

Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley and Yuichi Sugiyama
Drug Metabolism and Disposition December 1, 2011, 39 (12) 2361-2369; DOI: https://doi.org/10.1124/dmd.111.041814
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