Research ArticleArticle
Elucidation of a Novel Bioactivation Pathway of a 3,4-Unsubstituted Isoxazole in Human Liver Microsomes: Formation of a Glutathione Adduct of a Cyanoacrolein Derivative after Isoxazole Ring Opening
Jian Yu, James J. Folmer, Valerie Hoesch, James Doherty, James B. Campbell and Doug Burdette
Drug Metabolism and Disposition February 2011, 39 (2) 302-311; DOI: https://doi.org/10.1124/dmd.110.036285