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Research ArticleArticle

Brain Tissue Binding of Drugs: Evaluation and Validation of Solid Supported Porcine Brain Membrane Vesicles (TRANSIL) as a Novel High-Throughput Method

Raffaele Longhi, Silvia Corbioli, Stefano Fontana, Federicia Vinco, Simone Braggio, Lydia Helmdach, Jürgen Schiller and Hinnerk Boriss
Drug Metabolism and Disposition February 2011, 39 (2) 312-321; DOI: https://doi.org/10.1124/dmd.110.036095

Article Information

vol. 39 no. 2 312-321
DOI 
https://doi.org/10.1124/dmd.110.036095
PubMed 
21071520
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 25, 2010
  • Accepted November 11, 2010
  • Published online January 18, 2011.

Article Versions

Copyright & Usage 
Copyright © 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Raffaele Longhi,
  2. Silvia Corbioli,
  3. Stefano Fontana,
  4. Federicia Vinco,
  5. Simone Braggio,
  6. Lydia Helmdach,
  7. Jürgen Schiller and
  8. Hinnerk Boriss
  1. GlaxoSmithKline Neurosciences Centre of Excellence for Drug Discovery, Verona, Italy (R.L., S.C., S.F., F.V., S.B.); Sovicell GmbH, Leipzig, Germany (L.H., H.B.); and Universität Leipzig, Medizinische Fakultät, Institut für Medizinische Physik und Biophysik, Leipzig, Germany (J.S.)
  1. Address correspondence to:
    Raffaele Longhi, Aptuit Verona, Via Fleming 4, 37135 Verona, Italy. E-mail: raffaele.longhi{at}aptuit.com
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Research ArticleArticle

Brain Tissue Binding of Drugs: Evaluation and Validation of Solid Supported Porcine Brain Membrane Vesicles (TRANSIL) as a Novel High-Throughput Method

Raffaele Longhi, Silvia Corbioli, Stefano Fontana, Federicia Vinco, Simone Braggio, Lydia Helmdach, Jürgen Schiller and Hinnerk Boriss
Drug Metabolism and Disposition February 1, 2011, 39 (2) 312-321; DOI: https://doi.org/10.1124/dmd.110.036095
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