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Index by author

March 01, 2011; Volume 39,Issue 3

A

  1. Abe, Koji

    1. Decreased Hepatic Breast Cancer Resistance Protein Expression and Function in Multidrug Resistance-Associated Protein 2-Deficient (TR−) Rats
      Wei Yue, Jin Kyung Lee, Koji Abe, Yuichi Sugiyama and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2011, 39 (3) 441-447; DOI: https://doi.org/10.1124/dmd.110.035188

  2. Ahlin, Gustav

    1. Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods
      Markus Fridén, Fredrik Bergström, Hong Wan, Mikael Rehngren, Gustav Ahlin, Margareta Hammarlund-Udenaes and Ulf Bredberg
      Drug Metabolism and Disposition March 2011, 39 (3) 353-362; DOI: https://doi.org/10.1124/dmd.110.035998

  3. Akhlaghi, Fatemeh

    1. Diabetes Mellitus Reduces Activity of Human UDP-Glucuronosyltransferase 2B7 in Liver and Kidney Leading to Decreased Formation of Mycophenolic Acid Acyl-Glucuronide Metabolite
      Miroslav Dostalek, Michael H. Court, Suwagmani Hazarika and Fatemeh Akhlaghi
      Drug Metabolism and Disposition March 2011, 39 (3) 448-455; DOI: https://doi.org/10.1124/dmd.110.036608

  4. Alton, Kevin B.

    1. Characterization of Human Liver Enzymes Involved in the Biotransformation of Boceprevir, a Hepatitis C Virus Protease Inhibitor
      Anima Ghosal, Yuan Yuan, Wei Tong, Ai-Duen Su, Chunyan Gu, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition March 2011, 39 (3) 510-521; DOI: https://doi.org/10.1124/dmd.110.036996

  5. An, Guohua

    1. The Bioflavonoid Kaempferol Is an Abcg2 Substrate and Inhibits Abcg2-Mediated Quercetin Efflux
      Guohua An, Jorge Gallegos and Marilyn E. Morris
      Drug Metabolism and Disposition March 2011, 39 (3) 426-432; DOI: https://doi.org/10.1124/dmd.110.035212

  6. Anderson, Peter L.

    1. Atazanavir Metabolism According to CYP3A5 Status: An In Vitro-In Vivo Assessment
      Michael F. Wempe and Peter L. Anderson
      Drug Metabolism and Disposition March 2011, 39 (3) 522-527; DOI: https://doi.org/10.1124/dmd.110.036178

  7. Auriola, Seppo

    1. Simple, Direct, and Informative Method for the Assessment of CYP2C19 Enzyme Inactivation Kinetics
      Kaisa A. Salminen, Jukka Leppänen, Jarkko I. Venäläinen, Markku Pasanen, Seppo Auriola, Risto O. Juvonen and Hannu Raunio
      Drug Metabolism and Disposition March 2011, 39 (3) 412-418; DOI: https://doi.org/10.1124/dmd.110.036376

  8. Aw, Chiu Cheong

    1. Pharmacokinetic and Pharmacodynamic Properties of Cholinesterase Inhibitors Donepezil, Tacrine, and Galantamine in Aged and Young Lister Hooded Rats
      Catherine W. Goh, Chiu Cheong Aw, Jasinda H. Lee, Christopher P. Chen and Edward R. Browne
      Drug Metabolism and Disposition March 2011, 39 (3) 402-411; DOI: https://doi.org/10.1124/dmd.110.035964

B

  1. Bergström, Fredrik

    1. Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods
      Markus Fridén, Fredrik Bergström, Hong Wan, Mikael Rehngren, Gustav Ahlin, Margareta Hammarlund-Udenaes and Ulf Bredberg
      Drug Metabolism and Disposition March 2011, 39 (3) 353-362; DOI: https://doi.org/10.1124/dmd.110.035998

  2. Bhadhprasit, Wattanaporn

    1. Hepatocyte Nuclear Factor 4α Regulates Expression of the Mouse Female-Specific Cyp3a41 Gene in the Liver
      Wattanaporn Bhadhprasit, Tsutomu Sakuma, Yuki Kawasaki and Nobuo Nemoto
      Drug Metabolism and Disposition March 2011, 39 (3) 490-497; DOI: https://doi.org/10.1124/dmd.110.035980

  3. Bonomo, Fiorenza

    1. Casopitant: In Vitro Data and SimCyp Simulation to Predict In Vivo Metabolic Interactions Involving Cytochrome P450 3A4
      Paola Motta, Nicoletta Pons, Sabrina Pagliarusco, Mario Pellegatti and Fiorenza Bonomo
      Drug Metabolism and Disposition March 2011, 39 (3) 363-372; DOI: https://doi.org/10.1124/dmd.110.035071

  4. Branham, William

    1. Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
      Lei Guo, Stacey Dial, Leming Shi, William Branham, Jie Liu, Jia-Long Fang, Bridgett Green, Helen Deng, Jim Kaput and Baitang Ning
      Drug Metabolism and Disposition March 2011, 39 (3) 528-538; DOI: https://doi.org/10.1124/dmd.110.035873

  5. Bredberg, Ulf

    1. Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods
      Markus Fridén, Fredrik Bergström, Hong Wan, Mikael Rehngren, Gustav Ahlin, Margareta Hammarlund-Udenaes and Ulf Bredberg
      Drug Metabolism and Disposition March 2011, 39 (3) 353-362; DOI: https://doi.org/10.1124/dmd.110.035998

  6. Brouwer, Kim L. R.

    1. Decreased Hepatic Breast Cancer Resistance Protein Expression and Function in Multidrug Resistance-Associated Protein 2-Deficient (TR−) Rats
      Wei Yue, Jin Kyung Lee, Koji Abe, Yuichi Sugiyama and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2011, 39 (3) 441-447; DOI: https://doi.org/10.1124/dmd.110.035188

  7. Browne, Edward R.

    1. Pharmacokinetic and Pharmacodynamic Properties of Cholinesterase Inhibitors Donepezil, Tacrine, and Galantamine in Aged and Young Lister Hooded Rats
      Catherine W. Goh, Chiu Cheong Aw, Jasinda H. Lee, Christopher P. Chen and Edward R. Browne
      Drug Metabolism and Disposition March 2011, 39 (3) 402-411; DOI: https://doi.org/10.1124/dmd.110.035964

C

  1. Chen, Christopher P.

    1. Pharmacokinetic and Pharmacodynamic Properties of Cholinesterase Inhibitors Donepezil, Tacrine, and Galantamine in Aged and Young Lister Hooded Rats
      Catherine W. Goh, Chiu Cheong Aw, Jasinda H. Lee, Christopher P. Chen and Edward R. Browne
      Drug Metabolism and Disposition March 2011, 39 (3) 402-411; DOI: https://doi.org/10.1124/dmd.110.035964

  2. Chen, Guanming

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

  3. Chen, Ling-Jen

    1. Disposition and Metabolism of Cumene in F344 Rats and B6C3F1 Mice
      Ling-Jen Chen, Christopher J. Wegerski, Daniel J. Kramer, Leslie A. Thomas, Jacob D. McDonald, Kelly J. Dix and J. Michael Sanders
      Drug Metabolism and Disposition March 2011, 39 (3) 498-509; DOI: https://doi.org/10.1124/dmd.110.034769

  4. Chen, Xiaoyan

    1. Identification of 20(S)-Protopanaxadiol Metabolites in Human Liver Microsomes and Human Hepatocytes
      Liang Li, Xiaoyan Chen, Dan Li and Dafang Zhong
      Drug Metabolism and Disposition March 2011, 39 (3) 472-483; DOI: https://doi.org/10.1124/dmd.110.036723

  5. Chen, Yuan

    1. Utility of Intersystem Extrapolation Factors in Early Reaction Phenotyping and the Quantitative Extrapolation of Human Liver Microsomal Intrinsic Clearance Using Recombinant Cytochromes P450
      Yuan Chen, Liling Liu, Khanh Nguyen and Adrian J. Fretland
      Drug Metabolism and Disposition March 2011, 39 (3) 373-382; DOI: https://doi.org/10.1124/dmd.110.035147

  6. Chowdhury, Swapan K.

    1. Characterization of Human Liver Enzymes Involved in the Biotransformation of Boceprevir, a Hepatitis C Virus Protease Inhibitor
      Anima Ghosal, Yuan Yuan, Wei Tong, Ai-Duen Su, Chunyan Gu, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition March 2011, 39 (3) 510-521; DOI: https://doi.org/10.1124/dmd.110.036996

  7. Claxton, Christopher R. J.

    1. Control and Measurement of Plasma pH in Equilibrium Dialysis: Influence on Drug Plasma Protein Binding
      Ruth E. Curran, Christopher R. J. Claxton, Laura Hutchison, Paul J. Harradine, Iain J. Martin and Peter Littlewood
      Drug Metabolism and Disposition March 2011, 39 (3) 551-557; DOI: https://doi.org/10.1124/dmd.110.036988

  8. Court, Michael H.

    1. Diabetes Mellitus Reduces Activity of Human UDP-Glucuronosyltransferase 2B7 in Liver and Kidney Leading to Decreased Formation of Mycophenolic Acid Acyl-Glucuronide Metabolite
      Miroslav Dostalek, Michael H. Court, Suwagmani Hazarika and Fatemeh Akhlaghi
      Drug Metabolism and Disposition March 2011, 39 (3) 448-455; DOI: https://doi.org/10.1124/dmd.110.036608

  9. Curran, Ruth E.

    1. Control and Measurement of Plasma pH in Equilibrium Dialysis: Influence on Drug Plasma Protein Binding
      Ruth E. Curran, Christopher R. J. Claxton, Laura Hutchison, Paul J. Harradine, Iain J. Martin and Peter Littlewood
      Drug Metabolism and Disposition March 2011, 39 (3) 551-557; DOI: https://doi.org/10.1124/dmd.110.036988

D

  1. Dalvie, Deepak

    1. Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4
      Jyothi C. Talakad, Manish B. Shah, Gregory S. Walker, Cathie Xiang, James R. Halpert and Deepak Dalvie
      Drug Metabolism and Disposition March 2011, 39 (3) 539-550; DOI: https://doi.org/10.1124/dmd.110.037101

  2. Deng, Helen

    1. Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
      Lei Guo, Stacey Dial, Leming Shi, William Branham, Jie Liu, Jia-Long Fang, Bridgett Green, Helen Deng, Jim Kaput and Baitang Ning
      Drug Metabolism and Disposition March 2011, 39 (3) 528-538; DOI: https://doi.org/10.1124/dmd.110.035873

  3. Dial, Stacey

    1. Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
      Lei Guo, Stacey Dial, Leming Shi, William Branham, Jie Liu, Jia-Long Fang, Bridgett Green, Helen Deng, Jim Kaput and Baitang Ning
      Drug Metabolism and Disposition March 2011, 39 (3) 528-538; DOI: https://doi.org/10.1124/dmd.110.035873

  4. Dix, Kelly J.

    1. Disposition and Metabolism of Cumene in F344 Rats and B6C3F1 Mice
      Ling-Jen Chen, Christopher J. Wegerski, Daniel J. Kramer, Leslie A. Thomas, Jacob D. McDonald, Kelly J. Dix and J. Michael Sanders
      Drug Metabolism and Disposition March 2011, 39 (3) 498-509; DOI: https://doi.org/10.1124/dmd.110.034769

  5. Dostalek, Miroslav

    1. Diabetes Mellitus Reduces Activity of Human UDP-Glucuronosyltransferase 2B7 in Liver and Kidney Leading to Decreased Formation of Mycophenolic Acid Acyl-Glucuronide Metabolite
      Miroslav Dostalek, Michael H. Court, Suwagmani Hazarika and Fatemeh Akhlaghi
      Drug Metabolism and Disposition March 2011, 39 (3) 448-455; DOI: https://doi.org/10.1124/dmd.110.036608

F

  1. Fang, Jia-Long

    1. Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
      Lei Guo, Stacey Dial, Leming Shi, William Branham, Jie Liu, Jia-Long Fang, Bridgett Green, Helen Deng, Jim Kaput and Baitang Ning
      Drug Metabolism and Disposition March 2011, 39 (3) 528-538; DOI: https://doi.org/10.1124/dmd.110.035873

  2. Finel, Moshe

    1. Effects of Cell Differentiation and Assay Conditions on the UDP-Glucuronosyltransferase Activity in Caco-2 Cells
      Hongbo Zhang, Ari Tolonen, Timo Rousu, Jouni Hirvonen and Moshe Finel
      Drug Metabolism and Disposition March 2011, 39 (3) 456-464; DOI: https://doi.org/10.1124/dmd.110.036582

  3. Fretland, Adrian J.

    1. Utility of Intersystem Extrapolation Factors in Early Reaction Phenotyping and the Quantitative Extrapolation of Human Liver Microsomal Intrinsic Clearance Using Recombinant Cytochromes P450
      Yuan Chen, Liling Liu, Khanh Nguyen and Adrian J. Fretland
      Drug Metabolism and Disposition March 2011, 39 (3) 373-382; DOI: https://doi.org/10.1124/dmd.110.035147

  4. Freund, Amy

    1. Validation of Isolated Metabolites from Drug Metabolism Studies as Analytical Standards by Quantitative NMR
      Gregory S. Walker, Tim F. Ryder, Raman Sharma, Evan B. Smith and Amy Freund
      Drug Metabolism and Disposition March 2011, 39 (3) 433-440; DOI: https://doi.org/10.1124/dmd.110.036343

  5. Fridén, Markus

    1. Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods
      Markus Fridén, Fredrik Bergström, Hong Wan, Mikael Rehngren, Gustav Ahlin, Margareta Hammarlund-Udenaes and Ulf Bredberg
      Drug Metabolism and Disposition March 2011, 39 (3) 353-362; DOI: https://doi.org/10.1124/dmd.110.035998

G

  1. Gahir, Sarabjit S.

    1. Gestational and Pregnane X Receptor-Mediated Regulation of Placental ATP-Binding Cassette Drug Transporters in Mice
      Sarabjit S. Gahir and Micheline Piquette-Miller
      Drug Metabolism and Disposition March 2011, 39 (3) 465-471; DOI: https://doi.org/10.1124/dmd.110.034983

  2. Gallegos, Jorge

    1. The Bioflavonoid Kaempferol Is an Abcg2 Substrate and Inhibits Abcg2-Mediated Quercetin Efflux
      Guohua An, Jorge Gallegos and Marilyn E. Morris
      Drug Metabolism and Disposition March 2011, 39 (3) 426-432; DOI: https://doi.org/10.1124/dmd.110.035212

  3. Ghosal, Anima

    1. Characterization of Human Liver Enzymes Involved in the Biotransformation of Boceprevir, a Hepatitis C Virus Protease Inhibitor
      Anima Ghosal, Yuan Yuan, Wei Tong, Ai-Duen Su, Chunyan Gu, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition March 2011, 39 (3) 510-521; DOI: https://doi.org/10.1124/dmd.110.036996

  4. Goh, Catherine W.

    1. Pharmacokinetic and Pharmacodynamic Properties of Cholinesterase Inhibitors Donepezil, Tacrine, and Galantamine in Aged and Young Lister Hooded Rats
      Catherine W. Goh, Chiu Cheong Aw, Jasinda H. Lee, Christopher P. Chen and Edward R. Browne
      Drug Metabolism and Disposition March 2011, 39 (3) 402-411; DOI: https://doi.org/10.1124/dmd.110.035964

  5. Green, Bridgett

    1. Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
      Lei Guo, Stacey Dial, Leming Shi, William Branham, Jie Liu, Jia-Long Fang, Bridgett Green, Helen Deng, Jim Kaput and Baitang Ning
      Drug Metabolism and Disposition March 2011, 39 (3) 528-538; DOI: https://doi.org/10.1124/dmd.110.035873

  6. Gu, Chunyan

    1. Characterization of Human Liver Enzymes Involved in the Biotransformation of Boceprevir, a Hepatitis C Virus Protease Inhibitor
      Anima Ghosal, Yuan Yuan, Wei Tong, Ai-Duen Su, Chunyan Gu, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition March 2011, 39 (3) 510-521; DOI: https://doi.org/10.1124/dmd.110.036996

  7. Guo, Lei

    1. Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
      Lei Guo, Stacey Dial, Leming Shi, William Branham, Jie Liu, Jia-Long Fang, Bridgett Green, Helen Deng, Jim Kaput and Baitang Ning
      Drug Metabolism and Disposition March 2011, 39 (3) 528-538; DOI: https://doi.org/10.1124/dmd.110.035873

H

  1. Halpert, James R.

    1. Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4
      Jyothi C. Talakad, Manish B. Shah, Gregory S. Walker, Cathie Xiang, James R. Halpert and Deepak Dalvie
      Drug Metabolism and Disposition March 2011, 39 (3) 539-550; DOI: https://doi.org/10.1124/dmd.110.037101

  2. Hammarlund-Udenaes, Margareta

    1. Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods
      Markus Fridén, Fredrik Bergström, Hong Wan, Mikael Rehngren, Gustav Ahlin, Margareta Hammarlund-Udenaes and Ulf Bredberg
      Drug Metabolism and Disposition March 2011, 39 (3) 353-362; DOI: https://doi.org/10.1124/dmd.110.035998

  3. Harradine, Paul J.

    1. Control and Measurement of Plasma pH in Equilibrium Dialysis: Influence on Drug Plasma Protein Binding
      Ruth E. Curran, Christopher R. J. Claxton, Laura Hutchison, Paul J. Harradine, Iain J. Martin and Peter Littlewood
      Drug Metabolism and Disposition March 2011, 39 (3) 551-557; DOI: https://doi.org/10.1124/dmd.110.036988

  4. Hazarika, Suwagmani

    1. Diabetes Mellitus Reduces Activity of Human UDP-Glucuronosyltransferase 2B7 in Liver and Kidney Leading to Decreased Formation of Mycophenolic Acid Acyl-Glucuronide Metabolite
      Miroslav Dostalek, Michael H. Court, Suwagmani Hazarika and Fatemeh Akhlaghi
      Drug Metabolism and Disposition March 2011, 39 (3) 448-455; DOI: https://doi.org/10.1124/dmd.110.036608

  5. Hirvonen, Jouni

    1. Effects of Cell Differentiation and Assay Conditions on the UDP-Glucuronosyltransferase Activity in Caco-2 Cells
      Hongbo Zhang, Ari Tolonen, Timo Rousu, Jouni Hirvonen and Moshe Finel
      Drug Metabolism and Disposition March 2011, 39 (3) 456-464; DOI: https://doi.org/10.1124/dmd.110.036582

  6. Horinouchi, Hirohisa

    1. Repeated Injection of High Doses of Hemoglobin-Encapsulated Liposomes (Hemoglobin Vesicles) Induces Accelerated Blood Clearance in a Hemorrhagic Shock Rat Model
      Kazuaki Taguchi, Yasunori Iwao, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Koichi Kobayashi, Hirohisa Horinouchi, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition March 2011, 39 (3) 484-489; DOI: https://doi.org/10.1124/dmd.110.036913

  7. Hu, Nan

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

  8. Hutchison, Laura

    1. Control and Measurement of Plasma pH in Equilibrium Dialysis: Influence on Drug Plasma Protein Binding
      Ruth E. Curran, Christopher R. J. Claxton, Laura Hutchison, Paul J. Harradine, Iain J. Martin and Peter Littlewood
      Drug Metabolism and Disposition March 2011, 39 (3) 551-557; DOI: https://doi.org/10.1124/dmd.110.036988

I

  1. Iwao, Yasunori

    1. Repeated Injection of High Doses of Hemoglobin-Encapsulated Liposomes (Hemoglobin Vesicles) Induces Accelerated Blood Clearance in a Hemorrhagic Shock Rat Model
      Kazuaki Taguchi, Yasunori Iwao, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Koichi Kobayashi, Hirohisa Horinouchi, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition March 2011, 39 (3) 484-489; DOI: https://doi.org/10.1124/dmd.110.036913

J

  1. Jones, Hannah M.

    1. Prediction of Oral Pharmacokinetics of cMet Kinase Inhibitors in Humans: Physiologically Based Pharmacokinetic Model Versus Traditional One-Compartment Model
      Shinji Yamazaki, Judith Skaptason, David Romero, Sylvia Vekich, Hannah M. Jones, Weiwei Tan, Keith D. Wilner and Tatiana Koudriakova
      Drug Metabolism and Disposition March 2011, 39 (3) 383-393; DOI: https://doi.org/10.1124/dmd.110.035857

  2. Juvonen, Risto O.

    1. Simple, Direct, and Informative Method for the Assessment of CYP2C19 Enzyme Inactivation Kinetics
      Kaisa A. Salminen, Jukka Leppänen, Jarkko I. Venäläinen, Markku Pasanen, Seppo Auriola, Risto O. Juvonen and Hannu Raunio
      Drug Metabolism and Disposition March 2011, 39 (3) 412-418; DOI: https://doi.org/10.1124/dmd.110.036376

K

  1. Kadowaki, Daisuke

    1. Repeated Injection of High Doses of Hemoglobin-Encapsulated Liposomes (Hemoglobin Vesicles) Induces Accelerated Blood Clearance in a Hemorrhagic Shock Rat Model
      Kazuaki Taguchi, Yasunori Iwao, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Koichi Kobayashi, Hirohisa Horinouchi, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition March 2011, 39 (3) 484-489; DOI: https://doi.org/10.1124/dmd.110.036913

  2. Kaput, Jim

    1. Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
      Lei Guo, Stacey Dial, Leming Shi, William Branham, Jie Liu, Jia-Long Fang, Bridgett Green, Helen Deng, Jim Kaput and Baitang Ning
      Drug Metabolism and Disposition March 2011, 39 (3) 528-538; DOI: https://doi.org/10.1124/dmd.110.035873

  3. Kawasaki, Yuki

    1. Hepatocyte Nuclear Factor 4α Regulates Expression of the Mouse Female-Specific Cyp3a41 Gene in the Liver
      Wattanaporn Bhadhprasit, Tsutomu Sakuma, Yuki Kawasaki and Nobuo Nemoto
      Drug Metabolism and Disposition March 2011, 39 (3) 490-497; DOI: https://doi.org/10.1124/dmd.110.035980

  4. Kim, Richard B.

    1. Endoxifen, the Active Metabolite of Tamoxifen, Is a Substrate of the Efflux Transporter P-Glycoprotein (Multidrug Resistance 1)
      Wendy A. Teft, Sara E. Mansell and Richard B. Kim
      Drug Metabolism and Disposition March 2011, 39 (3) 558-562; DOI: https://doi.org/10.1124/dmd.110.036160

  5. Kishnani, Narendra S.

    1. Characterization of Human Liver Enzymes Involved in the Biotransformation of Boceprevir, a Hepatitis C Virus Protease Inhibitor
      Anima Ghosal, Yuan Yuan, Wei Tong, Ai-Duen Su, Chunyan Gu, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition March 2011, 39 (3) 510-521; DOI: https://doi.org/10.1124/dmd.110.036996

  6. Kobayashi, Koichi

    1. Repeated Injection of High Doses of Hemoglobin-Encapsulated Liposomes (Hemoglobin Vesicles) Induces Accelerated Blood Clearance in a Hemorrhagic Shock Rat Model
      Kazuaki Taguchi, Yasunori Iwao, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Koichi Kobayashi, Hirohisa Horinouchi, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition March 2011, 39 (3) 484-489; DOI: https://doi.org/10.1124/dmd.110.036913

  7. Koudriakova, Tatiana

    1. Prediction of Oral Pharmacokinetics of cMet Kinase Inhibitors in Humans: Physiologically Based Pharmacokinetic Model Versus Traditional One-Compartment Model
      Shinji Yamazaki, Judith Skaptason, David Romero, Sylvia Vekich, Hannah M. Jones, Weiwei Tan, Keith D. Wilner and Tatiana Koudriakova
      Drug Metabolism and Disposition March 2011, 39 (3) 383-393; DOI: https://doi.org/10.1124/dmd.110.035857

  8. Kramer, Daniel J.

    1. Disposition and Metabolism of Cumene in F344 Rats and B6C3F1 Mice
      Ling-Jen Chen, Christopher J. Wegerski, Daniel J. Kramer, Leslie A. Thomas, Jacob D. McDonald, Kelly J. Dix and J. Michael Sanders
      Drug Metabolism and Disposition March 2011, 39 (3) 498-509; DOI: https://doi.org/10.1124/dmd.110.034769

L

  1. Lee, Jasinda H.

    1. Pharmacokinetic and Pharmacodynamic Properties of Cholinesterase Inhibitors Donepezil, Tacrine, and Galantamine in Aged and Young Lister Hooded Rats
      Catherine W. Goh, Chiu Cheong Aw, Jasinda H. Lee, Christopher P. Chen and Edward R. Browne
      Drug Metabolism and Disposition March 2011, 39 (3) 402-411; DOI: https://doi.org/10.1124/dmd.110.035964

  2. Lee, Jin Kyung

    1. Decreased Hepatic Breast Cancer Resistance Protein Expression and Function in Multidrug Resistance-Associated Protein 2-Deficient (TR−) Rats
      Wei Yue, Jin Kyung Lee, Koji Abe, Yuichi Sugiyama and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2011, 39 (3) 441-447; DOI: https://doi.org/10.1124/dmd.110.035188

  3. Leppänen, Jukka

    1. Simple, Direct, and Informative Method for the Assessment of CYP2C19 Enzyme Inactivation Kinetics
      Kaisa A. Salminen, Jukka Leppänen, Jarkko I. Venäläinen, Markku Pasanen, Seppo Auriola, Risto O. Juvonen and Hannu Raunio
      Drug Metabolism and Disposition March 2011, 39 (3) 412-418; DOI: https://doi.org/10.1124/dmd.110.036376

  4. Li, Dan

    1. Identification of 20(S)-Protopanaxadiol Metabolites in Human Liver Microsomes and Human Hepatocytes
      Liang Li, Xiaoyan Chen, Dan Li and Dafang Zhong
      Drug Metabolism and Disposition March 2011, 39 (3) 472-483; DOI: https://doi.org/10.1124/dmd.110.036723

  5. Li, Feng

    1. CYP3A-Mediated Generation of Aldehyde and Hydrazine in Atazanavir Metabolism
      Feng Li, Jie Lu, Laiyou Wang and Xiaochao Ma
      Drug Metabolism and Disposition March 2011, 39 (3) 394-401; DOI: https://doi.org/10.1124/dmd.110.036327

  6. Li, Liang

    1. Identification of 20(S)-Protopanaxadiol Metabolites in Human Liver Microsomes and Human Hepatocytes
      Liang Li, Xiaoyan Chen, Dan Li and Dafang Zhong
      Drug Metabolism and Disposition March 2011, 39 (3) 472-483; DOI: https://doi.org/10.1124/dmd.110.036723

  7. Littlewood, Peter

    1. Control and Measurement of Plasma pH in Equilibrium Dialysis: Influence on Drug Plasma Protein Binding
      Ruth E. Curran, Christopher R. J. Claxton, Laura Hutchison, Paul J. Harradine, Iain J. Martin and Peter Littlewood
      Drug Metabolism and Disposition March 2011, 39 (3) 551-557; DOI: https://doi.org/10.1124/dmd.110.036988

  8. Liu, Haiyan

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

  9. Liu, Jie

    1. Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
      Lei Guo, Stacey Dial, Leming Shi, William Branham, Jie Liu, Jia-Long Fang, Bridgett Green, Helen Deng, Jim Kaput and Baitang Ning
      Drug Metabolism and Disposition March 2011, 39 (3) 528-538; DOI: https://doi.org/10.1124/dmd.110.035873

  10. Liu, Li

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

  11. Liu, Liling

    1. Utility of Intersystem Extrapolation Factors in Early Reaction Phenotyping and the Quantitative Extrapolation of Human Liver Microsomal Intrinsic Clearance Using Recombinant Cytochromes P450
      Yuan Chen, Liling Liu, Khanh Nguyen and Adrian J. Fretland
      Drug Metabolism and Disposition March 2011, 39 (3) 373-382; DOI: https://doi.org/10.1124/dmd.110.035147

  12. Liu, Xiang

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

  13. Liu, Xiaodong

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

  14. Lu, Jie

    1. CYP3A-Mediated Generation of Aldehyde and Hydrazine in Atazanavir Metabolism
      Feng Li, Jie Lu, Laiyou Wang and Xiaochao Ma
      Drug Metabolism and Disposition March 2011, 39 (3) 394-401; DOI: https://doi.org/10.1124/dmd.110.036327

M

  1. Ma, Xiaochao

    1. CYP3A-Mediated Generation of Aldehyde and Hydrazine in Atazanavir Metabolism
      Feng Li, Jie Lu, Laiyou Wang and Xiaochao Ma
      Drug Metabolism and Disposition March 2011, 39 (3) 394-401; DOI: https://doi.org/10.1124/dmd.110.036327

  2. Mansell, Sara E.

    1. Endoxifen, the Active Metabolite of Tamoxifen, Is a Substrate of the Efflux Transporter P-Glycoprotein (Multidrug Resistance 1)
      Wendy A. Teft, Sara E. Mansell and Richard B. Kim
      Drug Metabolism and Disposition March 2011, 39 (3) 558-562; DOI: https://doi.org/10.1124/dmd.110.036160

  3. Martin, Iain J.

    1. Control and Measurement of Plasma pH in Equilibrium Dialysis: Influence on Drug Plasma Protein Binding
      Ruth E. Curran, Christopher R. J. Claxton, Laura Hutchison, Paul J. Harradine, Iain J. Martin and Peter Littlewood
      Drug Metabolism and Disposition March 2011, 39 (3) 551-557; DOI: https://doi.org/10.1124/dmd.110.036988

  4. Maruyama, Toru

    1. Repeated Injection of High Doses of Hemoglobin-Encapsulated Liposomes (Hemoglobin Vesicles) Induces Accelerated Blood Clearance in a Hemorrhagic Shock Rat Model
      Kazuaki Taguchi, Yasunori Iwao, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Koichi Kobayashi, Hirohisa Horinouchi, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition March 2011, 39 (3) 484-489; DOI: https://doi.org/10.1124/dmd.110.036913

  5. McDonald, Jacob D.

    1. Disposition and Metabolism of Cumene in F344 Rats and B6C3F1 Mice
      Ling-Jen Chen, Christopher J. Wegerski, Daniel J. Kramer, Leslie A. Thomas, Jacob D. McDonald, Kelly J. Dix and J. Michael Sanders
      Drug Metabolism and Disposition March 2011, 39 (3) 498-509; DOI: https://doi.org/10.1124/dmd.110.034769

  6. Morris, Marilyn E.

    1. The Bioflavonoid Kaempferol Is an Abcg2 Substrate and Inhibits Abcg2-Mediated Quercetin Efflux
      Guohua An, Jorge Gallegos and Marilyn E. Morris
      Drug Metabolism and Disposition March 2011, 39 (3) 426-432; DOI: https://doi.org/10.1124/dmd.110.035212

  7. Motta, Paola

    1. Casopitant: In Vitro Data and SimCyp Simulation to Predict In Vivo Metabolic Interactions Involving Cytochrome P450 3A4
      Paola Motta, Nicoletta Pons, Sabrina Pagliarusco, Mario Pellegatti and Fiorenza Bonomo
      Drug Metabolism and Disposition March 2011, 39 (3) 363-372; DOI: https://doi.org/10.1124/dmd.110.035071

N

  1. Nemoto, Nobuo

    1. Hepatocyte Nuclear Factor 4α Regulates Expression of the Mouse Female-Specific Cyp3a41 Gene in the Liver
      Wattanaporn Bhadhprasit, Tsutomu Sakuma, Yuki Kawasaki and Nobuo Nemoto
      Drug Metabolism and Disposition March 2011, 39 (3) 490-497; DOI: https://doi.org/10.1124/dmd.110.035980

  2. Nguyen, Khanh

    1. Utility of Intersystem Extrapolation Factors in Early Reaction Phenotyping and the Quantitative Extrapolation of Human Liver Microsomal Intrinsic Clearance Using Recombinant Cytochromes P450
      Yuan Chen, Liling Liu, Khanh Nguyen and Adrian J. Fretland
      Drug Metabolism and Disposition March 2011, 39 (3) 373-382; DOI: https://doi.org/10.1124/dmd.110.035147

  3. Ning, Baitang

    1. Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
      Lei Guo, Stacey Dial, Leming Shi, William Branham, Jie Liu, Jia-Long Fang, Bridgett Green, Helen Deng, Jim Kaput and Baitang Ning
      Drug Metabolism and Disposition March 2011, 39 (3) 528-538; DOI: https://doi.org/10.1124/dmd.110.035873

O

  1. Otagiri, Masaki

    1. Repeated Injection of High Doses of Hemoglobin-Encapsulated Liposomes (Hemoglobin Vesicles) Induces Accelerated Blood Clearance in a Hemorrhagic Shock Rat Model
      Kazuaki Taguchi, Yasunori Iwao, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Koichi Kobayashi, Hirohisa Horinouchi, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition March 2011, 39 (3) 484-489; DOI: https://doi.org/10.1124/dmd.110.036913

P

  1. Pagliarusco, Sabrina

    1. Casopitant: In Vitro Data and SimCyp Simulation to Predict In Vivo Metabolic Interactions Involving Cytochrome P450 3A4
      Paola Motta, Nicoletta Pons, Sabrina Pagliarusco, Mario Pellegatti and Fiorenza Bonomo
      Drug Metabolism and Disposition March 2011, 39 (3) 363-372; DOI: https://doi.org/10.1124/dmd.110.035071

  2. Pan, Xian

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

  3. Pasanen, Markku

    1. Simple, Direct, and Informative Method for the Assessment of CYP2C19 Enzyme Inactivation Kinetics
      Kaisa A. Salminen, Jukka Leppänen, Jarkko I. Venäläinen, Markku Pasanen, Seppo Auriola, Risto O. Juvonen and Hannu Raunio
      Drug Metabolism and Disposition March 2011, 39 (3) 412-418; DOI: https://doi.org/10.1124/dmd.110.036376

  4. Pellegatti, Mario

    1. Casopitant: In Vitro Data and SimCyp Simulation to Predict In Vivo Metabolic Interactions Involving Cytochrome P450 3A4
      Paola Motta, Nicoletta Pons, Sabrina Pagliarusco, Mario Pellegatti and Fiorenza Bonomo
      Drug Metabolism and Disposition March 2011, 39 (3) 363-372; DOI: https://doi.org/10.1124/dmd.110.035071

  5. Piquette-Miller, Micheline

    1. Gestational and Pregnane X Receptor-Mediated Regulation of Placental ATP-Binding Cassette Drug Transporters in Mice
      Sarabjit S. Gahir and Micheline Piquette-Miller
      Drug Metabolism and Disposition March 2011, 39 (3) 465-471; DOI: https://doi.org/10.1124/dmd.110.034983

  6. Pons, Nicoletta

    1. Casopitant: In Vitro Data and SimCyp Simulation to Predict In Vivo Metabolic Interactions Involving Cytochrome P450 3A4
      Paola Motta, Nicoletta Pons, Sabrina Pagliarusco, Mario Pellegatti and Fiorenza Bonomo
      Drug Metabolism and Disposition March 2011, 39 (3) 363-372; DOI: https://doi.org/10.1124/dmd.110.035071

R

  1. Raunio, Hannu

    1. Simple, Direct, and Informative Method for the Assessment of CYP2C19 Enzyme Inactivation Kinetics
      Kaisa A. Salminen, Jukka Leppänen, Jarkko I. Venäläinen, Markku Pasanen, Seppo Auriola, Risto O. Juvonen and Hannu Raunio
      Drug Metabolism and Disposition March 2011, 39 (3) 412-418; DOI: https://doi.org/10.1124/dmd.110.036376

  2. Rehngren, Mikael

    1. Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods
      Markus Fridén, Fredrik Bergström, Hong Wan, Mikael Rehngren, Gustav Ahlin, Margareta Hammarlund-Udenaes and Ulf Bredberg
      Drug Metabolism and Disposition March 2011, 39 (3) 353-362; DOI: https://doi.org/10.1124/dmd.110.035998

  3. Romero, David

    1. Prediction of Oral Pharmacokinetics of cMet Kinase Inhibitors in Humans: Physiologically Based Pharmacokinetic Model Versus Traditional One-Compartment Model
      Shinji Yamazaki, Judith Skaptason, David Romero, Sylvia Vekich, Hannah M. Jones, Weiwei Tan, Keith D. Wilner and Tatiana Koudriakova
      Drug Metabolism and Disposition March 2011, 39 (3) 383-393; DOI: https://doi.org/10.1124/dmd.110.035857

  4. Rousu, Timo

    1. Effects of Cell Differentiation and Assay Conditions on the UDP-Glucuronosyltransferase Activity in Caco-2 Cells
      Hongbo Zhang, Ari Tolonen, Timo Rousu, Jouni Hirvonen and Moshe Finel
      Drug Metabolism and Disposition March 2011, 39 (3) 456-464; DOI: https://doi.org/10.1124/dmd.110.036582

  5. Ryder, Tim F.

    1. Validation of Isolated Metabolites from Drug Metabolism Studies as Analytical Standards by Quantitative NMR
      Gregory S. Walker, Tim F. Ryder, Raman Sharma, Evan B. Smith and Amy Freund
      Drug Metabolism and Disposition March 2011, 39 (3) 433-440; DOI: https://doi.org/10.1124/dmd.110.036343

S

  1. Sakai, Hiromi

    1. Repeated Injection of High Doses of Hemoglobin-Encapsulated Liposomes (Hemoglobin Vesicles) Induces Accelerated Blood Clearance in a Hemorrhagic Shock Rat Model
      Kazuaki Taguchi, Yasunori Iwao, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Koichi Kobayashi, Hirohisa Horinouchi, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition March 2011, 39 (3) 484-489; DOI: https://doi.org/10.1124/dmd.110.036913

  2. Sakuma, Tsutomu

    1. Hepatocyte Nuclear Factor 4α Regulates Expression of the Mouse Female-Specific Cyp3a41 Gene in the Liver
      Wattanaporn Bhadhprasit, Tsutomu Sakuma, Yuki Kawasaki and Nobuo Nemoto
      Drug Metabolism and Disposition March 2011, 39 (3) 490-497; DOI: https://doi.org/10.1124/dmd.110.035980

  3. Salminen, Kaisa A.

    1. Simple, Direct, and Informative Method for the Assessment of CYP2C19 Enzyme Inactivation Kinetics
      Kaisa A. Salminen, Jukka Leppänen, Jarkko I. Venäläinen, Markku Pasanen, Seppo Auriola, Risto O. Juvonen and Hannu Raunio
      Drug Metabolism and Disposition March 2011, 39 (3) 412-418; DOI: https://doi.org/10.1124/dmd.110.036376

  4. Sanders, J. Michael

    1. Disposition and Metabolism of Cumene in F344 Rats and B6C3F1 Mice
      Ling-Jen Chen, Christopher J. Wegerski, Daniel J. Kramer, Leslie A. Thomas, Jacob D. McDonald, Kelly J. Dix and J. Michael Sanders
      Drug Metabolism and Disposition March 2011, 39 (3) 498-509; DOI: https://doi.org/10.1124/dmd.110.034769

  5. Shah, Manish B.

    1. Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4
      Jyothi C. Talakad, Manish B. Shah, Gregory S. Walker, Cathie Xiang, James R. Halpert and Deepak Dalvie
      Drug Metabolism and Disposition March 2011, 39 (3) 539-550; DOI: https://doi.org/10.1124/dmd.110.037101

  6. Sharma, Raman

    1. Validation of Isolated Metabolites from Drug Metabolism Studies as Analytical Standards by Quantitative NMR
      Gregory S. Walker, Tim F. Ryder, Raman Sharma, Evan B. Smith and Amy Freund
      Drug Metabolism and Disposition March 2011, 39 (3) 433-440; DOI: https://doi.org/10.1124/dmd.110.036343

  7. Shi, Leming

    1. Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
      Lei Guo, Stacey Dial, Leming Shi, William Branham, Jie Liu, Jia-Long Fang, Bridgett Green, Helen Deng, Jim Kaput and Baitang Ning
      Drug Metabolism and Disposition March 2011, 39 (3) 528-538; DOI: https://doi.org/10.1124/dmd.110.035873

  8. Skaptason, Judith

    1. Prediction of Oral Pharmacokinetics of cMet Kinase Inhibitors in Humans: Physiologically Based Pharmacokinetic Model Versus Traditional One-Compartment Model
      Shinji Yamazaki, Judith Skaptason, David Romero, Sylvia Vekich, Hannah M. Jones, Weiwei Tan, Keith D. Wilner and Tatiana Koudriakova
      Drug Metabolism and Disposition March 2011, 39 (3) 383-393; DOI: https://doi.org/10.1124/dmd.110.035857

  9. Smith, Evan B.

    1. Validation of Isolated Metabolites from Drug Metabolism Studies as Analytical Standards by Quantitative NMR
      Gregory S. Walker, Tim F. Ryder, Raman Sharma, Evan B. Smith and Amy Freund
      Drug Metabolism and Disposition March 2011, 39 (3) 433-440; DOI: https://doi.org/10.1124/dmd.110.036343

  10. Su, Ai-Duen

    1. Characterization of Human Liver Enzymes Involved in the Biotransformation of Boceprevir, a Hepatitis C Virus Protease Inhibitor
      Anima Ghosal, Yuan Yuan, Wei Tong, Ai-Duen Su, Chunyan Gu, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition March 2011, 39 (3) 510-521; DOI: https://doi.org/10.1124/dmd.110.036996

  11. Sugiyama, Yuichi

    1. Decreased Hepatic Breast Cancer Resistance Protein Expression and Function in Multidrug Resistance-Associated Protein 2-Deficient (TR−) Rats
      Wei Yue, Jin Kyung Lee, Koji Abe, Yuichi Sugiyama and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2011, 39 (3) 441-447; DOI: https://doi.org/10.1124/dmd.110.035188

T

  1. Taguchi, Kazuaki

    1. Repeated Injection of High Doses of Hemoglobin-Encapsulated Liposomes (Hemoglobin Vesicles) Induces Accelerated Blood Clearance in a Hemorrhagic Shock Rat Model
      Kazuaki Taguchi, Yasunori Iwao, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Koichi Kobayashi, Hirohisa Horinouchi, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition March 2011, 39 (3) 484-489; DOI: https://doi.org/10.1124/dmd.110.036913

  2. Talakad, Jyothi C.

    1. Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4
      Jyothi C. Talakad, Manish B. Shah, Gregory S. Walker, Cathie Xiang, James R. Halpert and Deepak Dalvie
      Drug Metabolism and Disposition March 2011, 39 (3) 539-550; DOI: https://doi.org/10.1124/dmd.110.037101

  3. Tan, Weiwei

    1. Prediction of Oral Pharmacokinetics of cMet Kinase Inhibitors in Humans: Physiologically Based Pharmacokinetic Model Versus Traditional One-Compartment Model
      Shinji Yamazaki, Judith Skaptason, David Romero, Sylvia Vekich, Hannah M. Jones, Weiwei Tan, Keith D. Wilner and Tatiana Koudriakova
      Drug Metabolism and Disposition March 2011, 39 (3) 383-393; DOI: https://doi.org/10.1124/dmd.110.035857

  4. Teft, Wendy A.

    1. Endoxifen, the Active Metabolite of Tamoxifen, Is a Substrate of the Efflux Transporter P-Glycoprotein (Multidrug Resistance 1)
      Wendy A. Teft, Sara E. Mansell and Richard B. Kim
      Drug Metabolism and Disposition March 2011, 39 (3) 558-562; DOI: https://doi.org/10.1124/dmd.110.036160

  5. Thomas, Leslie A.

    1. Disposition and Metabolism of Cumene in F344 Rats and B6C3F1 Mice
      Ling-Jen Chen, Christopher J. Wegerski, Daniel J. Kramer, Leslie A. Thomas, Jacob D. McDonald, Kelly J. Dix and J. Michael Sanders
      Drug Metabolism and Disposition March 2011, 39 (3) 498-509; DOI: https://doi.org/10.1124/dmd.110.034769

  6. Tolonen, Ari

    1. Effects of Cell Differentiation and Assay Conditions on the UDP-Glucuronosyltransferase Activity in Caco-2 Cells
      Hongbo Zhang, Ari Tolonen, Timo Rousu, Jouni Hirvonen and Moshe Finel
      Drug Metabolism and Disposition March 2011, 39 (3) 456-464; DOI: https://doi.org/10.1124/dmd.110.036582

  7. Tong, Wei

    1. Characterization of Human Liver Enzymes Involved in the Biotransformation of Boceprevir, a Hepatitis C Virus Protease Inhibitor
      Anima Ghosal, Yuan Yuan, Wei Tong, Ai-Duen Su, Chunyan Gu, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition March 2011, 39 (3) 510-521; DOI: https://doi.org/10.1124/dmd.110.036996

V

  1. Vekich, Sylvia

    1. Prediction of Oral Pharmacokinetics of cMet Kinase Inhibitors in Humans: Physiologically Based Pharmacokinetic Model Versus Traditional One-Compartment Model
      Shinji Yamazaki, Judith Skaptason, David Romero, Sylvia Vekich, Hannah M. Jones, Weiwei Tan, Keith D. Wilner and Tatiana Koudriakova
      Drug Metabolism and Disposition March 2011, 39 (3) 383-393; DOI: https://doi.org/10.1124/dmd.110.035857

  2. Venäläinen, Jarkko I.

    1. Simple, Direct, and Informative Method for the Assessment of CYP2C19 Enzyme Inactivation Kinetics
      Kaisa A. Salminen, Jukka Leppänen, Jarkko I. Venäläinen, Markku Pasanen, Seppo Auriola, Risto O. Juvonen and Hannu Raunio
      Drug Metabolism and Disposition March 2011, 39 (3) 412-418; DOI: https://doi.org/10.1124/dmd.110.036376

W

  1. Walker, Gregory S.

    1. Validation of Isolated Metabolites from Drug Metabolism Studies as Analytical Standards by Quantitative NMR
      Gregory S. Walker, Tim F. Ryder, Raman Sharma, Evan B. Smith and Amy Freund
      Drug Metabolism and Disposition March 2011, 39 (3) 433-440; DOI: https://doi.org/10.1124/dmd.110.036343
    2. Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4
      Jyothi C. Talakad, Manish B. Shah, Gregory S. Walker, Cathie Xiang, James R. Halpert and Deepak Dalvie
      Drug Metabolism and Disposition March 2011, 39 (3) 539-550; DOI: https://doi.org/10.1124/dmd.110.037101

  2. Wan, Hong

    1. Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods
      Markus Fridén, Fredrik Bergström, Hong Wan, Mikael Rehngren, Gustav Ahlin, Margareta Hammarlund-Udenaes and Ulf Bredberg
      Drug Metabolism and Disposition March 2011, 39 (3) 353-362; DOI: https://doi.org/10.1124/dmd.110.035998

  3. Wang, Guangji

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

  4. Wang, Laiyou

    1. CYP3A-Mediated Generation of Aldehyde and Hydrazine in Atazanavir Metabolism
      Feng Li, Jie Lu, Laiyou Wang and Xiaochao Ma
      Drug Metabolism and Disposition March 2011, 39 (3) 394-401; DOI: https://doi.org/10.1124/dmd.110.036327

  5. Wang, Xinting

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

  6. Watanabe, Hiroshi

    1. Repeated Injection of High Doses of Hemoglobin-Encapsulated Liposomes (Hemoglobin Vesicles) Induces Accelerated Blood Clearance in a Hemorrhagic Shock Rat Model
      Kazuaki Taguchi, Yasunori Iwao, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Koichi Kobayashi, Hirohisa Horinouchi, Toru Maruyama and Masaki Otagiri
      Drug Metabolism and Disposition March 2011, 39 (3) 484-489; DOI: https://doi.org/10.1124/dmd.110.036913

  7. Wegerski, Christopher J.

    1. Disposition and Metabolism of Cumene in F344 Rats and B6C3F1 Mice
      Ling-Jen Chen, Christopher J. Wegerski, Daniel J. Kramer, Leslie A. Thomas, Jacob D. McDonald, Kelly J. Dix and J. Michael Sanders
      Drug Metabolism and Disposition March 2011, 39 (3) 498-509; DOI: https://doi.org/10.1124/dmd.110.034769

  8. Wempe, Michael F.

    1. Atazanavir Metabolism According to CYP3A5 Status: An In Vitro-In Vivo Assessment
      Michael F. Wempe and Peter L. Anderson
      Drug Metabolism and Disposition March 2011, 39 (3) 522-527; DOI: https://doi.org/10.1124/dmd.110.036178

  9. Wilner, Keith D.

    1. Prediction of Oral Pharmacokinetics of cMet Kinase Inhibitors in Humans: Physiologically Based Pharmacokinetic Model Versus Traditional One-Compartment Model
      Shinji Yamazaki, Judith Skaptason, David Romero, Sylvia Vekich, Hannah M. Jones, Weiwei Tan, Keith D. Wilner and Tatiana Koudriakova
      Drug Metabolism and Disposition March 2011, 39 (3) 383-393; DOI: https://doi.org/10.1124/dmd.110.035857

X

  1. Xiang, Cathie

    1. Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4
      Jyothi C. Talakad, Manish B. Shah, Gregory S. Walker, Cathie Xiang, James R. Halpert and Deepak Dalvie
      Drug Metabolism and Disposition March 2011, 39 (3) 539-550; DOI: https://doi.org/10.1124/dmd.110.037101

  2. Xie, Lin

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

  3. Xie, Shanshan

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

Y

  1. Yamazaki, Shinji

    1. Prediction of Oral Pharmacokinetics of cMet Kinase Inhibitors in Humans: Physiologically Based Pharmacokinetic Model Versus Traditional One-Compartment Model
      Shinji Yamazaki, Judith Skaptason, David Romero, Sylvia Vekich, Hannah M. Jones, Weiwei Tan, Keith D. Wilner and Tatiana Koudriakova
      Drug Metabolism and Disposition March 2011, 39 (3) 383-393; DOI: https://doi.org/10.1124/dmd.110.035857

  2. Yuan, Yuan

    1. Characterization of Human Liver Enzymes Involved in the Biotransformation of Boceprevir, a Hepatitis C Virus Protease Inhibitor
      Anima Ghosal, Yuan Yuan, Wei Tong, Ai-Duen Su, Chunyan Gu, Swapan K. Chowdhury, Narendra S. Kishnani and Kevin B. Alton
      Drug Metabolism and Disposition March 2011, 39 (3) 510-521; DOI: https://doi.org/10.1124/dmd.110.036996

  3. Yue, Wei

    1. Decreased Hepatic Breast Cancer Resistance Protein Expression and Function in Multidrug Resistance-Associated Protein 2-Deficient (TR−) Rats
      Wei Yue, Jin Kyung Lee, Koji Abe, Yuichi Sugiyama and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2011, 39 (3) 441-447; DOI: https://doi.org/10.1124/dmd.110.035188

Z

  1. Zhang, Hongbo

    1. Effects of Cell Differentiation and Assay Conditions on the UDP-Glucuronosyltransferase Activity in Caco-2 Cells
      Hongbo Zhang, Ari Tolonen, Timo Rousu, Jouni Hirvonen and Moshe Finel
      Drug Metabolism and Disposition March 2011, 39 (3) 456-464; DOI: https://doi.org/10.1124/dmd.110.036582

  2. Zhang, Lulu

    1. Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats
      Nan Hu, Shanshan Xie, Li Liu, Xinting Wang, Xian Pan, Guanming Chen, Lulu Zhang, Haiyan Liu, Xiang Liu, Xiaodong Liu, Lin Xie and Guangji Wang
      Drug Metabolism and Disposition March 2011, 39 (3) 419-425; DOI: https://doi.org/10.1124/dmd.110.035642

  3. Zhong, Dafang

    1. Identification of 20(S)-Protopanaxadiol Metabolites in Human Liver Microsomes and Human Hepatocytes
      Liang Li, Xiaoyan Chen, Dan Li and Dafang Zhong
      Drug Metabolism and Disposition March 2011, 39 (3) 472-483; DOI: https://doi.org/10.1124/dmd.110.036723
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