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Research ArticleArticle

Casopitant: In Vitro Data and SimCyp Simulation to Predict In Vivo Metabolic Interactions Involving Cytochrome P450 3A4

Paola Motta, Nicoletta Pons, Sabrina Pagliarusco, Mario Pellegatti and Fiorenza Bonomo
Drug Metabolism and Disposition March 2011, 39 (3) 363-372; DOI: https://doi.org/10.1124/dmd.110.035071

Article Information

vol. 39 no. 3 363-372
DOI 
https://doi.org/10.1124/dmd.110.035071
PubMed 
21149541
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 22, 2010
  • Accepted December 13, 2010
  • Published online February 17, 2011.

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Copyright & Usage 
Copyright © 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Paola Motta,
  2. Nicoletta Pons,
  3. Sabrina Pagliarusco,
  4. Mario Pellegatti and
  5. Fiorenza Bonomo
  1. Department of Drug Metabolism and Pharmacokinetics, Medicine Research Center, GlaxoSmithKline, Verona, Italy
  1. Address correspondence to:
    Dr. Paola Motta, DMPK Aptuit Verona S.r.l., Via Fleming 4, 37135 Verona, Italy. E-mail: paola.motta{at}aptuit.com
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Research ArticleArticle

Casopitant: In Vitro Data and SimCyp Simulation to Predict In Vivo Metabolic Interactions Involving Cytochrome P450 3A4

Paola Motta, Nicoletta Pons, Sabrina Pagliarusco, Mario Pellegatti and Fiorenza Bonomo
Drug Metabolism and Disposition March 1, 2011, 39 (3) 363-372; DOI: https://doi.org/10.1124/dmd.110.035071
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