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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

May 01, 2011; Volume 39,Issue 5
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Adachi, Yasuhisa

    1. You have access
      Organic Anion Transporter 3 Mediates the Efflux Transport of an Amphipathic Organic Anion, Dehydroepiandrosterone Sulfate, across the Blood-Brain Barrier in Mice
      Mari Miyajima, Hiroyuki Kusuhara, Miki Fujishima, Yasuhisa Adachi and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2011, 39 (5) 814-819; DOI: https://doi.org/10.1124/dmd.110.036863
  2. Akiyama, Yuko

    1. You have access
      Sorafenib and Sunitinib, Two Anticancer Drugs, Inhibit CYP3A4-Mediated and Activate CY3A5-Mediated Midazolam 1′-Hydroxylation
      Minako Sugiyama, Ken-ichi Fujita, Norie Murayama, Yuko Akiyama, Hiroshi Yamazaki and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2011, 39 (5) 757-762; DOI: https://doi.org/10.1124/dmd.110.037853
  3. Allentoff, Alban

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341
  4. An, Nianzhen

    1. You have access
      Evaluation of the Effects of 20 Nonsynonymous Single Nucleotide Polymorphisms of CYP2C19 on S-Mephenytoin 4′-Hydroxylation and Omeprazole 5′-Hydroxylation
      Huijuan Wang, Nianzhen An, Hao Wang, Yiwen Gao, Duan Liu, Ting Bian, Juanli Zhu and Chao Chen
      Drug Metabolism and Disposition May 2011, 39 (5) 830-837; DOI: https://doi.org/10.1124/dmd.110.037549
  5. Andersson, Marine L.

    1. You have access
      Seasonal Variation in Blood Drug Concentrations and a Potential Relationship to Vitamin D
      Jonatan D. Lindh, Marine L. Andersson, Erik Eliasson and Linda Björkhem-Bergman
      Drug Metabolism and Disposition May 2011, 39 (5) 933-937; DOI: https://doi.org/10.1124/dmd.111.038125
  6. Arora, Vinod

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341

B

  1. Backman, Janne T.

    1. You have access
      Reevaluation of the Microsomal Metabolism of Montelukast: Major Contribution by CYP2C8 at Clinically Relevant Concentrations
      Anne M. Filppula, Jouko Laitila, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition May 2011, 39 (5) 904-911; DOI: https://doi.org/10.1124/dmd.110.037689
  2. Balogh, Larissa

    1. You have access
      Pharmacokinetic Interaction of the Antiparasitic Agents Ivermectin and Spinosad in Dogs
      Stewart T. Dunn, Laura Hedges, Kathleen E. Sampson, Yurong Lai, Sean Mahabir, Larissa Balogh and Charles W. Locuson
      Drug Metabolism and Disposition May 2011, 39 (5) 789-795; DOI: https://doi.org/10.1124/dmd.110.034827
  3. Bao, Narisu

    1. You have access
      Contribution of Carboxylesterase in Hamster to the Intestinal First-Pass Loss and Low Bioavailability of Ethyl Piperate, an Effective Lipid-Lowering Drug Candidate
      Youli Lu, Narisu Bao, Gereltu Borjihan, Yanling Ma, Miaomiao Hu, Chen Yu, Shuijun Li, Jingying Jia, Ding Yang and Yiping Wang
      Drug Metabolism and Disposition May 2011, 39 (5) 796-802; DOI: https://doi.org/10.1124/dmd.110.037614
  4. Barbuch, Robert J.

    1. You have access
      Metabolism of LY654322, a Growth Hormone Secretagogue, to an Unusual Diimidazopyridine Metabolite
      Anthony G. Borel, Timothy M. Jones, Robert J. Barbuch, David A. Jackson, Palaniappan Kulanthaivel, Edward Mattiuz, Valentine J. Klimkowski, William J. Wheeler and Gregory A. Rener
      Drug Metabolism and Disposition May 2011, 39 (5) 740-749; DOI: https://doi.org/10.1124/dmd.110.037598
  5. Bast, Aalt

    1. You have access
      Identification of the Metabolites of the Antioxidant Flavonoid 7-Mono-O-(β-hydroxyethyl)-rutoside in Mice
      Hilde Jacobs, Ron Peters, Gertjan J. M. den Hartog, Wim J. F. van der Vijgh, Aalt Bast and Guido R. M. M. Haenen
      Drug Metabolism and Disposition May 2011, 39 (5) 750-756; DOI: https://doi.org/10.1124/dmd.110.036525
  6. Bateman, Kevin

    1. You have access
      Novel Cytochrome P450-Mediated Ring Opening of the 1,3,4-Oxadiazole in Setileuton, a 5-Lipoxygenase Inhibitor
      Cheri M. Maciolek, Bennett Ma, Karsten Menzel, Sebastien Laliberte, Kevin Bateman, Paul Krolikowski and Christoper R. Gibson
      Drug Metabolism and Disposition May 2011, 39 (5) 763-770; DOI: https://doi.org/10.1124/dmd.110.037366
  7. Beijnen, Jos H.

    1. You have access
      Differential Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) on Axitinib Brain Accumulation and Oral Plasma Pharmacokinetics
      Birk Poller, Dilek Iusuf, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
      Drug Metabolism and Disposition May 2011, 39 (5) 729-735; DOI: https://doi.org/10.1124/dmd.110.037317
  8. Bian, Ting

    1. You have access
      Evaluation of the Effects of 20 Nonsynonymous Single Nucleotide Polymorphisms of CYP2C19 on S-Mephenytoin 4′-Hydroxylation and Omeprazole 5′-Hydroxylation
      Huijuan Wang, Nianzhen An, Hao Wang, Yiwen Gao, Duan Liu, Ting Bian, Juanli Zhu and Chao Chen
      Drug Metabolism and Disposition May 2011, 39 (5) 830-837; DOI: https://doi.org/10.1124/dmd.110.037549
  9. Björkhem-Bergman, Linda

    1. You have access
      Seasonal Variation in Blood Drug Concentrations and a Potential Relationship to Vitamin D
      Jonatan D. Lindh, Marine L. Andersson, Erik Eliasson and Linda Björkhem-Bergman
      Drug Metabolism and Disposition May 2011, 39 (5) 933-937; DOI: https://doi.org/10.1124/dmd.111.038125
  10. Bondesson, Ulf

    1. You have access
      In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
      Anna Lundahl, Mikael Hedeland, Ulf Bondesson and Hans Lennernäs
      Drug Metabolism and Disposition May 2011, 39 (5) 847-857; DOI: https://doi.org/10.1124/dmd.110.035311
  11. Borel, Anthony G.

    1. You have access
      Metabolism of LY654322, a Growth Hormone Secretagogue, to an Unusual Diimidazopyridine Metabolite
      Anthony G. Borel, Timothy M. Jones, Robert J. Barbuch, David A. Jackson, Palaniappan Kulanthaivel, Edward Mattiuz, Valentine J. Klimkowski, William J. Wheeler and Gregory A. Rener
      Drug Metabolism and Disposition May 2011, 39 (5) 740-749; DOI: https://doi.org/10.1124/dmd.110.037598
  12. Borjihan, Gereltu

    1. You have access
      Contribution of Carboxylesterase in Hamster to the Intestinal First-Pass Loss and Low Bioavailability of Ethyl Piperate, an Effective Lipid-Lowering Drug Candidate
      Youli Lu, Narisu Bao, Gereltu Borjihan, Yanling Ma, Miaomiao Hu, Chen Yu, Shuijun Li, Jingying Jia, Ding Yang and Yiping Wang
      Drug Metabolism and Disposition May 2011, 39 (5) 796-802; DOI: https://doi.org/10.1124/dmd.110.037614
  13. Bredberg, Ulf

    1. You have access
      Optimal Experimental Design for Assessment of Enzyme Kinetics in a Drug Discovery Screening Environment
      Erik Sjögren, Joakim Nyberg, Mats O. Magnusson, Hans Lennernäs, Andrew Hooker and Ulf Bredberg
      Drug Metabolism and Disposition May 2011, 39 (5) 858-863; DOI: https://doi.org/10.1124/dmd.110.037309
  14. Brenneman, Debbie

    1. You have access
      Liver-Selective Expression of Human Arylamine N-Acetyltransferase NAT2 in Transgenic Mice
      Kim S. Sugamori, Debbie Brenneman and Denis M. Grant
      Drug Metabolism and Disposition May 2011, 39 (5) 882-890; DOI: https://doi.org/10.1124/dmd.111.038216

C

  1. Caceres-Cortes, Janet

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341
  2. Chen, Chao

    1. You have access
      Evaluation of the Effects of 20 Nonsynonymous Single Nucleotide Polymorphisms of CYP2C19 on S-Mephenytoin 4′-Hydroxylation and Omeprazole 5′-Hydroxylation
      Huijuan Wang, Nianzhen An, Hao Wang, Yiwen Gao, Duan Liu, Ting Bian, Juanli Zhu and Chao Chen
      Drug Metabolism and Disposition May 2011, 39 (5) 830-837; DOI: https://doi.org/10.1124/dmd.110.037549
  3. Cheng, Kunrong

    1. You have access
      In Vivo Magnetic Resonance Imaging to Detect Biliary Excretion of 19F-Labeled Drug in Mice
      Jean-Pierre Raufman, Su Xu, Kunrong Cheng, Sandeep Khurana, Diana Johnson, Changxing Shao, Maureen A. Kane, Da Shi, Rao Gullapalli and James Polli
      Drug Metabolism and Disposition May 2011, 39 (5) 736-739; DOI: https://doi.org/10.1124/dmd.110.037358
  4. Christopher, Lisa J.

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341
  5. Collier, Abby C.

    1. You have access
      The Development of UDP-Glucuronosyltransferases 1A1 and 1A6 in the Pediatric Liver
      Shogo J. Miyagi and Abby C. Collier
      Drug Metabolism and Disposition May 2011, 39 (5) 912-919; DOI: https://doi.org/10.1124/dmd.110.037192
  6. Cubitt, Helen E.

    1. You have access
      Prediction of Human Drug Clearance by Multiple Metabolic Pathways: Integration of Hepatic and Intestinal Microsomal and Cytosolic Data
      Helen E. Cubitt, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition May 2011, 39 (5) 864-873; DOI: https://doi.org/10.1124/dmd.110.036566

D

  1. Deguchi, Tsuneo

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457
  2. den Hartog, Gertjan J. M.

    1. You have access
      Identification of the Metabolites of the Antioxidant Flavonoid 7-Mono-O-(β-hydroxyethyl)-rutoside in Mice
      Hilde Jacobs, Ron Peters, Gertjan J. M. den Hartog, Wim J. F. van der Vijgh, Aalt Bast and Guido R. M. M. Haenen
      Drug Metabolism and Disposition May 2011, 39 (5) 750-756; DOI: https://doi.org/10.1124/dmd.110.036525
  3. Doroshyenko, Oxana

    1. You have access
      Effect of the CYP2C8 Genotype on the Pharmacokinetics and Pharmacodynamics of Repaglinide
      Dorota Tomalik-Scharte, Uwe Fuhr, Martin Hellmich, Dorothee Frank, Oxana Doroshyenko, Alexander Jetter and Julia C. Stingl
      Drug Metabolism and Disposition May 2011, 39 (5) 927-932; DOI: https://doi.org/10.1124/dmd.110.036921
  4. Dunn, Stewart T.

    1. You have access
      Pharmacokinetic Interaction of the Antiparasitic Agents Ivermectin and Spinosad in Dogs
      Stewart T. Dunn, Laura Hedges, Kathleen E. Sampson, Yurong Lai, Sean Mahabir, Larissa Balogh and Charles W. Locuson
      Drug Metabolism and Disposition May 2011, 39 (5) 789-795; DOI: https://doi.org/10.1124/dmd.110.034827

E

  1. Eliasson, Erik

    1. You have access
      Seasonal Variation in Blood Drug Concentrations and a Potential Relationship to Vitamin D
      Jonatan D. Lindh, Marine L. Andersson, Erik Eliasson and Linda Björkhem-Bergman
      Drug Metabolism and Disposition May 2011, 39 (5) 933-937; DOI: https://doi.org/10.1124/dmd.111.038125

F

  1. Filppula, Anne M.

    1. You have access
      Reevaluation of the Microsomal Metabolism of Montelukast: Major Contribution by CYP2C8 at Clinically Relevant Concentrations
      Anne M. Filppula, Jouko Laitila, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition May 2011, 39 (5) 904-911; DOI: https://doi.org/10.1124/dmd.110.037689
  2. Frank, Dorothee

    1. You have access
      Effect of the CYP2C8 Genotype on the Pharmacokinetics and Pharmacodynamics of Repaglinide
      Dorota Tomalik-Scharte, Uwe Fuhr, Martin Hellmich, Dorothee Frank, Oxana Doroshyenko, Alexander Jetter and Julia C. Stingl
      Drug Metabolism and Disposition May 2011, 39 (5) 927-932; DOI: https://doi.org/10.1124/dmd.110.036921
  3. Fuhr, Uwe

    1. You have access
      Effect of the CYP2C8 Genotype on the Pharmacokinetics and Pharmacodynamics of Repaglinide
      Dorota Tomalik-Scharte, Uwe Fuhr, Martin Hellmich, Dorothee Frank, Oxana Doroshyenko, Alexander Jetter and Julia C. Stingl
      Drug Metabolism and Disposition May 2011, 39 (5) 927-932; DOI: https://doi.org/10.1124/dmd.110.036921
  4. Fujishima, Miki

    1. You have access
      Organic Anion Transporter 3 Mediates the Efflux Transport of an Amphipathic Organic Anion, Dehydroepiandrosterone Sulfate, across the Blood-Brain Barrier in Mice
      Mari Miyajima, Hiroyuki Kusuhara, Miki Fujishima, Yasuhisa Adachi and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2011, 39 (5) 814-819; DOI: https://doi.org/10.1124/dmd.110.036863
  5. Fujita, Ken-ichi

    1. You have access
      Sorafenib and Sunitinib, Two Anticancer Drugs, Inhibit CYP3A4-Mediated and Activate CY3A5-Mediated Midazolam 1′-Hydroxylation
      Minako Sugiyama, Ken-ichi Fujita, Norie Murayama, Yuko Akiyama, Hiroshi Yamazaki and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2011, 39 (5) 757-762; DOI: https://doi.org/10.1124/dmd.110.037853
  6. Fukami, Tatsuki

    1. You have access
      CYP2C9-Mediated Metabolic Activation of Losartan Detected by a Highly Sensitive Cell-Based Screening Assay
      Atsushi Iwamura, Tatsuki Fukami, Hiroko Hosomi, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition May 2011, 39 (5) 838-846; DOI: https://doi.org/10.1124/dmd.110.037259
  7. Fukumoto, Hiroyuki

    1. You have access
      Metabolism of the c-Fos/Activator Protein-1 Inhibitor T-5224 by Multiple Human UDP-Glucuronosyltransferase Isoforms
      Shinsuke Uchihashi, Hiroyuki Fukumoto, Makoto Onoda, Hiroyoshi Hayakawa, Shin-ichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition May 2011, 39 (5) 803-813; DOI: https://doi.org/10.1124/dmd.110.037952
  8. Furuta, Yoshitake

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457
  9. Fusegawa, Keiichi

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457

G

  1. Galetin, Aleksandra

    1. You have access
      Prediction of Human Drug Clearance by Multiple Metabolic Pathways: Integration of Hepatic and Intestinal Microsomal and Cytosolic Data
      Helen E. Cubitt, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition May 2011, 39 (5) 864-873; DOI: https://doi.org/10.1124/dmd.110.036566
  2. Gan, Jinping

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341
  3. Gandhi, Adarsh

    1. You have access
      Differential Role of Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein in Toll-Like Receptor 2-Mediated Regulation of Gene Expression of Hepatic Cytokines and Drug-Metabolizing Enzymes
      Romi Ghose, Tao Guo, Jesus G. Vallejo and Adarsh Gandhi
      Drug Metabolism and Disposition May 2011, 39 (5) 874-881; DOI: https://doi.org/10.1124/dmd.110.037382
  4. Gao, Yiwen

    1. You have access
      Evaluation of the Effects of 20 Nonsynonymous Single Nucleotide Polymorphisms of CYP2C19 on S-Mephenytoin 4′-Hydroxylation and Omeprazole 5′-Hydroxylation
      Huijuan Wang, Nianzhen An, Hao Wang, Yiwen Gao, Duan Liu, Ting Bian, Juanli Zhu and Chao Chen
      Drug Metabolism and Disposition May 2011, 39 (5) 830-837; DOI: https://doi.org/10.1124/dmd.110.037549
  5. Ghose, Romi

    1. You have access
      Differential Role of Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein in Toll-Like Receptor 2-Mediated Regulation of Gene Expression of Hepatic Cytokines and Drug-Metabolizing Enzymes
      Romi Ghose, Tao Guo, Jesus G. Vallejo and Adarsh Gandhi
      Drug Metabolism and Disposition May 2011, 39 (5) 874-881; DOI: https://doi.org/10.1124/dmd.110.037382
  6. Gibson, Christoper R.

    1. You have access
      Novel Cytochrome P450-Mediated Ring Opening of the 1,3,4-Oxadiazole in Setileuton, a 5-Lipoxygenase Inhibitor
      Cheri M. Maciolek, Bennett Ma, Karsten Menzel, Sebastien Laliberte, Kevin Bateman, Paul Krolikowski and Christoper R. Gibson
      Drug Metabolism and Disposition May 2011, 39 (5) 763-770; DOI: https://doi.org/10.1124/dmd.110.037366
  7. Gong, Jiachang

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341
  8. Grant, Denis M.

    1. You have access
      Liver-Selective Expression of Human Arylamine N-Acetyltransferase NAT2 in Transgenic Mice
      Kim S. Sugamori, Debbie Brenneman and Denis M. Grant
      Drug Metabolism and Disposition May 2011, 39 (5) 882-890; DOI: https://doi.org/10.1124/dmd.111.038216
  9. Gullapalli, Rao

    1. You have access
      In Vivo Magnetic Resonance Imaging to Detect Biliary Excretion of 19F-Labeled Drug in Mice
      Jean-Pierre Raufman, Su Xu, Kunrong Cheng, Sandeep Khurana, Diana Johnson, Changxing Shao, Maureen A. Kane, Da Shi, Rao Gullapalli and James Polli
      Drug Metabolism and Disposition May 2011, 39 (5) 736-739; DOI: https://doi.org/10.1124/dmd.110.037358
  10. Guo, Tao

    1. You have access
      Differential Role of Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein in Toll-Like Receptor 2-Mediated Regulation of Gene Expression of Hepatic Cytokines and Drug-Metabolizing Enzymes
      Romi Ghose, Tao Guo, Jesus G. Vallejo and Adarsh Gandhi
      Drug Metabolism and Disposition May 2011, 39 (5) 874-881; DOI: https://doi.org/10.1124/dmd.110.037382

H

  1. Haenen, Guido R. M. M.

    1. You have access
      Identification of the Metabolites of the Antioxidant Flavonoid 7-Mono-O-(β-hydroxyethyl)-rutoside in Mice
      Hilde Jacobs, Ron Peters, Gertjan J. M. den Hartog, Wim J. F. van der Vijgh, Aalt Bast and Guido R. M. M. Haenen
      Drug Metabolism and Disposition May 2011, 39 (5) 750-756; DOI: https://doi.org/10.1124/dmd.110.036525
  2. Hagenbuch, Bruno

    1. You have access
      Interactions of Green Tea Catechins with Organic Anion-Transporting Polypeptides
      Megan Roth, Barbara N. Timmermann and Bruno Hagenbuch
      Drug Metabolism and Disposition May 2011, 39 (5) 920-926; DOI: https://doi.org/10.1124/dmd.110.036640
  3. Hayakawa, Hiroyoshi

    1. You have access
      Metabolism of the c-Fos/Activator Protein-1 Inhibitor T-5224 by Multiple Human UDP-Glucuronosyltransferase Isoforms
      Shinsuke Uchihashi, Hiroyuki Fukumoto, Makoto Onoda, Hiroyoshi Hayakawa, Shin-ichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition May 2011, 39 (5) 803-813; DOI: https://doi.org/10.1124/dmd.110.037952
  4. Hedeland, Mikael

    1. You have access
      In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
      Anna Lundahl, Mikael Hedeland, Ulf Bondesson and Hans Lennernäs
      Drug Metabolism and Disposition May 2011, 39 (5) 847-857; DOI: https://doi.org/10.1124/dmd.110.035311
  5. Hedges, Laura

    1. You have access
      Pharmacokinetic Interaction of the Antiparasitic Agents Ivermectin and Spinosad in Dogs
      Stewart T. Dunn, Laura Hedges, Kathleen E. Sampson, Yurong Lai, Sean Mahabir, Larissa Balogh and Charles W. Locuson
      Drug Metabolism and Disposition May 2011, 39 (5) 789-795; DOI: https://doi.org/10.1124/dmd.110.034827
  6. Hellmich, Martin

    1. You have access
      Effect of the CYP2C8 Genotype on the Pharmacokinetics and Pharmacodynamics of Repaglinide
      Dorota Tomalik-Scharte, Uwe Fuhr, Martin Hellmich, Dorothee Frank, Oxana Doroshyenko, Alexander Jetter and Julia C. Stingl
      Drug Metabolism and Disposition May 2011, 39 (5) 927-932; DOI: https://doi.org/10.1124/dmd.110.036921
  7. Hirouchi, Masakazu

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457
  8. Hollenberg, Paul F.

    1. You have access
      Anandamide Oxidation by Wild-Type and Polymorphically Expressed CYP2B6 and CYP2D6
      Chitra Sridar, Natasha T. Snider and Paul F. Hollenberg
      Drug Metabolism and Disposition May 2011, 39 (5) 782-788; DOI: https://doi.org/10.1124/dmd.110.036707
  9. Hooker, Andrew

    1. You have access
      Optimal Experimental Design for Assessment of Enzyme Kinetics in a Drug Discovery Screening Environment
      Erik Sjögren, Joakim Nyberg, Mats O. Magnusson, Hans Lennernäs, Andrew Hooker and Ulf Bredberg
      Drug Metabolism and Disposition May 2011, 39 (5) 858-863; DOI: https://doi.org/10.1124/dmd.110.037309
  10. Hosomi, Hiroko

    1. You have access
      CYP2C9-Mediated Metabolic Activation of Losartan Detected by a Highly Sensitive Cell-Based Screening Assay
      Atsushi Iwamura, Tatsuki Fukami, Hiroko Hosomi, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition May 2011, 39 (5) 838-846; DOI: https://doi.org/10.1124/dmd.110.037259
  11. Houston, J. Brian

    1. You have access
      Prediction of Human Drug Clearance by Multiple Metabolic Pathways: Integration of Hepatic and Intestinal Microsomal and Cytosolic Data
      Helen E. Cubitt, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition May 2011, 39 (5) 864-873; DOI: https://doi.org/10.1124/dmd.110.036566
  12. Hu, Miaomiao

    1. You have access
      Contribution of Carboxylesterase in Hamster to the Intestinal First-Pass Loss and Low Bioavailability of Ethyl Piperate, an Effective Lipid-Lowering Drug Candidate
      Youli Lu, Narisu Bao, Gereltu Borjihan, Yanling Ma, Miaomiao Hu, Chen Yu, Shuijun Li, Jingying Jia, Ding Yang and Yiping Wang
      Drug Metabolism and Disposition May 2011, 39 (5) 796-802; DOI: https://doi.org/10.1124/dmd.110.037614

I

  1. Igeta, Katsuhiro

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457
  2. Ikenaga, Hidenori

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457
  3. Ikushiro, Shin-ichi

    1. You have access
      Metabolism of the c-Fos/Activator Protein-1 Inhibitor T-5224 by Multiple Human UDP-Glucuronosyltransferase Isoforms
      Shinsuke Uchihashi, Hiroyuki Fukumoto, Makoto Onoda, Hiroyoshi Hayakawa, Shin-ichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition May 2011, 39 (5) 803-813; DOI: https://doi.org/10.1124/dmd.110.037952
  4. Iusuf, Dilek

    1. You have access
      Differential Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) on Axitinib Brain Accumulation and Oral Plasma Pharmacokinetics
      Birk Poller, Dilek Iusuf, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
      Drug Metabolism and Disposition May 2011, 39 (5) 729-735; DOI: https://doi.org/10.1124/dmd.110.037317
  5. Iwamura, Atsushi

    1. You have access
      CYP2C9-Mediated Metabolic Activation of Losartan Detected by a Highly Sensitive Cell-Based Screening Assay
      Atsushi Iwamura, Tatsuki Fukami, Hiroko Hosomi, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition May 2011, 39 (5) 838-846; DOI: https://doi.org/10.1124/dmd.110.037259
  6. Iwasaki, Masaru

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457
  7. Iyer, Ramaswamy A.

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341
  8. Izumi, Takashi

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457

J

  1. Jackson, David A.

    1. You have access
      Metabolism of LY654322, a Growth Hormone Secretagogue, to an Unusual Diimidazopyridine Metabolite
      Anthony G. Borel, Timothy M. Jones, Robert J. Barbuch, David A. Jackson, Palaniappan Kulanthaivel, Edward Mattiuz, Valentine J. Klimkowski, William J. Wheeler and Gregory A. Rener
      Drug Metabolism and Disposition May 2011, 39 (5) 740-749; DOI: https://doi.org/10.1124/dmd.110.037598
  2. Jacobs, Hilde

    1. You have access
      Identification of the Metabolites of the Antioxidant Flavonoid 7-Mono-O-(β-hydroxyethyl)-rutoside in Mice
      Hilde Jacobs, Ron Peters, Gertjan J. M. den Hartog, Wim J. F. van der Vijgh, Aalt Bast and Guido R. M. M. Haenen
      Drug Metabolism and Disposition May 2011, 39 (5) 750-756; DOI: https://doi.org/10.1124/dmd.110.036525
  3. Jetter, Alexander

    1. You have access
      Effect of the CYP2C8 Genotype on the Pharmacokinetics and Pharmacodynamics of Repaglinide
      Dorota Tomalik-Scharte, Uwe Fuhr, Martin Hellmich, Dorothee Frank, Oxana Doroshyenko, Alexander Jetter and Julia C. Stingl
      Drug Metabolism and Disposition May 2011, 39 (5) 927-932; DOI: https://doi.org/10.1124/dmd.110.036921
  4. Jia, Jingying

    1. You have access
      Contribution of Carboxylesterase in Hamster to the Intestinal First-Pass Loss and Low Bioavailability of Ethyl Piperate, an Effective Lipid-Lowering Drug Candidate
      Youli Lu, Narisu Bao, Gereltu Borjihan, Yanling Ma, Miaomiao Hu, Chen Yu, Shuijun Li, Jingying Jia, Ding Yang and Yiping Wang
      Drug Metabolism and Disposition May 2011, 39 (5) 796-802; DOI: https://doi.org/10.1124/dmd.110.037614
  5. Johnson, Diana

    1. You have access
      In Vivo Magnetic Resonance Imaging to Detect Biliary Excretion of 19F-Labeled Drug in Mice
      Jean-Pierre Raufman, Su Xu, Kunrong Cheng, Sandeep Khurana, Diana Johnson, Changxing Shao, Maureen A. Kane, Da Shi, Rao Gullapalli and James Polli
      Drug Metabolism and Disposition May 2011, 39 (5) 736-739; DOI: https://doi.org/10.1124/dmd.110.037358
  6. Jones, Timothy M.

    1. You have access
      Metabolism of LY654322, a Growth Hormone Secretagogue, to an Unusual Diimidazopyridine Metabolite
      Anthony G. Borel, Timothy M. Jones, Robert J. Barbuch, David A. Jackson, Palaniappan Kulanthaivel, Edward Mattiuz, Valentine J. Klimkowski, William J. Wheeler and Gregory A. Rener
      Drug Metabolism and Disposition May 2011, 39 (5) 740-749; DOI: https://doi.org/10.1124/dmd.110.037598

K

  1. Kadam, Rajendra S.

    1. You have access
      Influence of Drug Solubility and Lipophilicity on Transscleral Retinal Delivery of Six Corticosteroids
      Ashish Thakur, Rajendra S. Kadam and Uday B. Kompella
      Drug Metabolism and Disposition May 2011, 39 (5) 771-781; DOI: https://doi.org/10.1124/dmd.110.037408
  2. Kane, Maureen A.

    1. You have access
      In Vivo Magnetic Resonance Imaging to Detect Biliary Excretion of 19F-Labeled Drug in Mice
      Jean-Pierre Raufman, Su Xu, Kunrong Cheng, Sandeep Khurana, Diana Johnson, Changxing Shao, Maureen A. Kane, Da Shi, Rao Gullapalli and James Polli
      Drug Metabolism and Disposition May 2011, 39 (5) 736-739; DOI: https://doi.org/10.1124/dmd.110.037358
  3. Khurana, Sandeep

    1. You have access
      In Vivo Magnetic Resonance Imaging to Detect Biliary Excretion of 19F-Labeled Drug in Mice
      Jean-Pierre Raufman, Su Xu, Kunrong Cheng, Sandeep Khurana, Diana Johnson, Changxing Shao, Maureen A. Kane, Da Shi, Rao Gullapalli and James Polli
      Drug Metabolism and Disposition May 2011, 39 (5) 736-739; DOI: https://doi.org/10.1124/dmd.110.037358
  4. Klimkowski, Valentine J.

    1. You have access
      Metabolism of LY654322, a Growth Hormone Secretagogue, to an Unusual Diimidazopyridine Metabolite
      Anthony G. Borel, Timothy M. Jones, Robert J. Barbuch, David A. Jackson, Palaniappan Kulanthaivel, Edward Mattiuz, Valentine J. Klimkowski, William J. Wheeler and Gregory A. Rener
      Drug Metabolism and Disposition May 2011, 39 (5) 740-749; DOI: https://doi.org/10.1124/dmd.110.037598
  5. Kompella, Uday B.

    1. You have access
      Influence of Drug Solubility and Lipophilicity on Transscleral Retinal Delivery of Six Corticosteroids
      Ashish Thakur, Rajendra S. Kadam and Uday B. Kompella
      Drug Metabolism and Disposition May 2011, 39 (5) 771-781; DOI: https://doi.org/10.1124/dmd.110.037408
  6. Krolikowski, Paul

    1. You have access
      Novel Cytochrome P450-Mediated Ring Opening of the 1,3,4-Oxadiazole in Setileuton, a 5-Lipoxygenase Inhibitor
      Cheri M. Maciolek, Bennett Ma, Karsten Menzel, Sebastien Laliberte, Kevin Bateman, Paul Krolikowski and Christoper R. Gibson
      Drug Metabolism and Disposition May 2011, 39 (5) 763-770; DOI: https://doi.org/10.1124/dmd.110.037366
  7. Kulanthaivel, Palaniappan

    1. You have access
      Metabolism of LY654322, a Growth Hormone Secretagogue, to an Unusual Diimidazopyridine Metabolite
      Anthony G. Borel, Timothy M. Jones, Robert J. Barbuch, David A. Jackson, Palaniappan Kulanthaivel, Edward Mattiuz, Valentine J. Klimkowski, William J. Wheeler and Gregory A. Rener
      Drug Metabolism and Disposition May 2011, 39 (5) 740-749; DOI: https://doi.org/10.1124/dmd.110.037598
  8. Kurihara, Atsushi

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457
  9. Kusuhara, Hiroyuki

    1. You have access
      Organic Anion Transporter 3 Mediates the Efflux Transport of an Amphipathic Organic Anion, Dehydroepiandrosterone Sulfate, across the Blood-Brain Barrier in Mice
      Mari Miyajima, Hiroyuki Kusuhara, Miki Fujishima, Yasuhisa Adachi and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2011, 39 (5) 814-819; DOI: https://doi.org/10.1124/dmd.110.036863

L

  1. Lago, Michael

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341
  2. Lai, Yurong

    1. You have access
      Pharmacokinetic Interaction of the Antiparasitic Agents Ivermectin and Spinosad in Dogs
      Stewart T. Dunn, Laura Hedges, Kathleen E. Sampson, Yurong Lai, Sean Mahabir, Larissa Balogh and Charles W. Locuson
      Drug Metabolism and Disposition May 2011, 39 (5) 789-795; DOI: https://doi.org/10.1124/dmd.110.034827
  3. Laitila, Jouko

    1. You have access
      Reevaluation of the Microsomal Metabolism of Montelukast: Major Contribution by CYP2C8 at Clinically Relevant Concentrations
      Anne M. Filppula, Jouko Laitila, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition May 2011, 39 (5) 904-911; DOI: https://doi.org/10.1124/dmd.110.037689
  4. Laliberte, Sebastien

    1. You have access
      Novel Cytochrome P450-Mediated Ring Opening of the 1,3,4-Oxadiazole in Setileuton, a 5-Lipoxygenase Inhibitor
      Cheri M. Maciolek, Bennett Ma, Karsten Menzel, Sebastien Laliberte, Kevin Bateman, Paul Krolikowski and Christoper R. Gibson
      Drug Metabolism and Disposition May 2011, 39 (5) 763-770; DOI: https://doi.org/10.1124/dmd.110.037366
  5. Lennernäs, Hans

    1. You have access
      In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
      Anna Lundahl, Mikael Hedeland, Ulf Bondesson and Hans Lennernäs
      Drug Metabolism and Disposition May 2011, 39 (5) 847-857; DOI: https://doi.org/10.1124/dmd.110.035311
    2. You have access
      Optimal Experimental Design for Assessment of Enzyme Kinetics in a Drug Discovery Screening Environment
      Erik Sjögren, Joakim Nyberg, Mats O. Magnusson, Hans Lennernäs, Andrew Hooker and Ulf Bredberg
      Drug Metabolism and Disposition May 2011, 39 (5) 858-863; DOI: https://doi.org/10.1124/dmd.110.037309
  6. Li, Shuijun

    1. You have access
      Contribution of Carboxylesterase in Hamster to the Intestinal First-Pass Loss and Low Bioavailability of Ethyl Piperate, an Effective Lipid-Lowering Drug Candidate
      Youli Lu, Narisu Bao, Gereltu Borjihan, Yanling Ma, Miaomiao Hu, Chen Yu, Shuijun Li, Jingying Jia, Ding Yang and Yiping Wang
      Drug Metabolism and Disposition May 2011, 39 (5) 796-802; DOI: https://doi.org/10.1124/dmd.110.037614
  7. Lindh, Jonatan D.

    1. You have access
      Seasonal Variation in Blood Drug Concentrations and a Potential Relationship to Vitamin D
      Jonatan D. Lindh, Marine L. Andersson, Erik Eliasson and Linda Björkhem-Bergman
      Drug Metabolism and Disposition May 2011, 39 (5) 933-937; DOI: https://doi.org/10.1124/dmd.111.038125
  8. Liu, Duan

    1. You have access
      Evaluation of the Effects of 20 Nonsynonymous Single Nucleotide Polymorphisms of CYP2C19 on S-Mephenytoin 4′-Hydroxylation and Omeprazole 5′-Hydroxylation
      Huijuan Wang, Nianzhen An, Hao Wang, Yiwen Gao, Duan Liu, Ting Bian, Juanli Zhu and Chao Chen
      Drug Metabolism and Disposition May 2011, 39 (5) 830-837; DOI: https://doi.org/10.1124/dmd.110.037549
  9. Locuson, Charles W.

    1. You have access
      Pharmacokinetic Interaction of the Antiparasitic Agents Ivermectin and Spinosad in Dogs
      Stewart T. Dunn, Laura Hedges, Kathleen E. Sampson, Yurong Lai, Sean Mahabir, Larissa Balogh and Charles W. Locuson
      Drug Metabolism and Disposition May 2011, 39 (5) 789-795; DOI: https://doi.org/10.1124/dmd.110.034827
  10. Lu, Youli

    1. You have access
      Contribution of Carboxylesterase in Hamster to the Intestinal First-Pass Loss and Low Bioavailability of Ethyl Piperate, an Effective Lipid-Lowering Drug Candidate
      Youli Lu, Narisu Bao, Gereltu Borjihan, Yanling Ma, Miaomiao Hu, Chen Yu, Shuijun Li, Jingying Jia, Ding Yang and Yiping Wang
      Drug Metabolism and Disposition May 2011, 39 (5) 796-802; DOI: https://doi.org/10.1124/dmd.110.037614
  11. Lundahl, Anna

    1. You have access
      In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
      Anna Lundahl, Mikael Hedeland, Ulf Bondesson and Hans Lennernäs
      Drug Metabolism and Disposition May 2011, 39 (5) 847-857; DOI: https://doi.org/10.1124/dmd.110.035311

M

  1. Ma, Bennett

    1. You have access
      Novel Cytochrome P450-Mediated Ring Opening of the 1,3,4-Oxadiazole in Setileuton, a 5-Lipoxygenase Inhibitor
      Cheri M. Maciolek, Bennett Ma, Karsten Menzel, Sebastien Laliberte, Kevin Bateman, Paul Krolikowski and Christoper R. Gibson
      Drug Metabolism and Disposition May 2011, 39 (5) 763-770; DOI: https://doi.org/10.1124/dmd.110.037366
  2. Ma, Yanling

    1. You have access
      Contribution of Carboxylesterase in Hamster to the Intestinal First-Pass Loss and Low Bioavailability of Ethyl Piperate, an Effective Lipid-Lowering Drug Candidate
      Youli Lu, Narisu Bao, Gereltu Borjihan, Yanling Ma, Miaomiao Hu, Chen Yu, Shuijun Li, Jingying Jia, Ding Yang and Yiping Wang
      Drug Metabolism and Disposition May 2011, 39 (5) 796-802; DOI: https://doi.org/10.1124/dmd.110.037614
  3. Maciolek, Cheri M.

    1. You have access
      Novel Cytochrome P450-Mediated Ring Opening of the 1,3,4-Oxadiazole in Setileuton, a 5-Lipoxygenase Inhibitor
      Cheri M. Maciolek, Bennett Ma, Karsten Menzel, Sebastien Laliberte, Kevin Bateman, Paul Krolikowski and Christoper R. Gibson
      Drug Metabolism and Disposition May 2011, 39 (5) 763-770; DOI: https://doi.org/10.1124/dmd.110.037366
  4. Magnusson, Mats O.

    1. You have access
      Optimal Experimental Design for Assessment of Enzyme Kinetics in a Drug Discovery Screening Environment
      Erik Sjögren, Joakim Nyberg, Mats O. Magnusson, Hans Lennernäs, Andrew Hooker and Ulf Bredberg
      Drug Metabolism and Disposition May 2011, 39 (5) 858-863; DOI: https://doi.org/10.1124/dmd.110.037309
  5. Mahabir, Sean

    1. You have access
      Pharmacokinetic Interaction of the Antiparasitic Agents Ivermectin and Spinosad in Dogs
      Stewart T. Dunn, Laura Hedges, Kathleen E. Sampson, Yurong Lai, Sean Mahabir, Larissa Balogh and Charles W. Locuson
      Drug Metabolism and Disposition May 2011, 39 (5) 789-795; DOI: https://doi.org/10.1124/dmd.110.034827
  6. Masson, Eric

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341
  7. Mattiuz, Edward

    1. You have access
      Metabolism of LY654322, a Growth Hormone Secretagogue, to an Unusual Diimidazopyridine Metabolite
      Anthony G. Borel, Timothy M. Jones, Robert J. Barbuch, David A. Jackson, Palaniappan Kulanthaivel, Edward Mattiuz, Valentine J. Klimkowski, William J. Wheeler and Gregory A. Rener
      Drug Metabolism and Disposition May 2011, 39 (5) 740-749; DOI: https://doi.org/10.1124/dmd.110.037598
  8. Menzel, Karsten

    1. You have access
      Novel Cytochrome P450-Mediated Ring Opening of the 1,3,4-Oxadiazole in Setileuton, a 5-Lipoxygenase Inhibitor
      Cheri M. Maciolek, Bennett Ma, Karsten Menzel, Sebastien Laliberte, Kevin Bateman, Paul Krolikowski and Christoper R. Gibson
      Drug Metabolism and Disposition May 2011, 39 (5) 763-770; DOI: https://doi.org/10.1124/dmd.110.037366
  9. Miyagi, Shogo J.

    1. You have access
      The Development of UDP-Glucuronosyltransferases 1A1 and 1A6 in the Pediatric Liver
      Shogo J. Miyagi and Abby C. Collier
      Drug Metabolism and Disposition May 2011, 39 (5) 912-919; DOI: https://doi.org/10.1124/dmd.110.037192
  10. Miyajima, Mari

    1. You have access
      Organic Anion Transporter 3 Mediates the Efflux Transport of an Amphipathic Organic Anion, Dehydroepiandrosterone Sulfate, across the Blood-Brain Barrier in Mice
      Mari Miyajima, Hiroyuki Kusuhara, Miki Fujishima, Yasuhisa Adachi and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2011, 39 (5) 814-819; DOI: https://doi.org/10.1124/dmd.110.036863
  11. Murata, Shinji

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457
  12. Murayama, Norie

    1. You have access
      Sorafenib and Sunitinib, Two Anticancer Drugs, Inhibit CYP3A4-Mediated and Activate CY3A5-Mediated Midazolam 1′-Hydroxylation
      Minako Sugiyama, Ken-ichi Fujita, Norie Murayama, Yuko Akiyama, Hiroshi Yamazaki and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2011, 39 (5) 757-762; DOI: https://doi.org/10.1124/dmd.110.037853

N

  1. Nakajima, Miki

    1. You have access
      CYP2C9-Mediated Metabolic Activation of Losartan Detected by a Highly Sensitive Cell-Based Screening Assay
      Atsushi Iwamura, Tatsuki Fukami, Hiroko Hosomi, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition May 2011, 39 (5) 838-846; DOI: https://doi.org/10.1124/dmd.110.037259
  2. Neuvonen, Pertti J.

    1. You have access
      Reevaluation of the Microsomal Metabolism of Montelukast: Major Contribution by CYP2C8 at Clinically Relevant Concentrations
      Anne M. Filppula, Jouko Laitila, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition May 2011, 39 (5) 904-911; DOI: https://doi.org/10.1124/dmd.110.037689
  3. Nyberg, Joakim

    1. You have access
      Optimal Experimental Design for Assessment of Enzyme Kinetics in a Drug Discovery Screening Environment
      Erik Sjögren, Joakim Nyberg, Mats O. Magnusson, Hans Lennernäs, Andrew Hooker and Ulf Bredberg
      Drug Metabolism and Disposition May 2011, 39 (5) 858-863; DOI: https://doi.org/10.1124/dmd.110.037309

O

  1. Okazaki, Osamu

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457
  2. Onoda, Makoto

    1. You have access
      Metabolism of the c-Fos/Activator Protein-1 Inhibitor T-5224 by Multiple Human UDP-Glucuronosyltransferase Isoforms
      Shinsuke Uchihashi, Hiroyuki Fukumoto, Makoto Onoda, Hiroyoshi Hayakawa, Shin-ichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition May 2011, 39 (5) 803-813; DOI: https://doi.org/10.1124/dmd.110.037952

P

  1. Peters, Ron

    1. You have access
      Identification of the Metabolites of the Antioxidant Flavonoid 7-Mono-O-(β-hydroxyethyl)-rutoside in Mice
      Hilde Jacobs, Ron Peters, Gertjan J. M. den Hartog, Wim J. F. van der Vijgh, Aalt Bast and Guido R. M. M. Haenen
      Drug Metabolism and Disposition May 2011, 39 (5) 750-756; DOI: https://doi.org/10.1124/dmd.110.036525
  2. Poller, Birk

    1. You have access
      Differential Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) on Axitinib Brain Accumulation and Oral Plasma Pharmacokinetics
      Birk Poller, Dilek Iusuf, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
      Drug Metabolism and Disposition May 2011, 39 (5) 729-735; DOI: https://doi.org/10.1124/dmd.110.037317
  3. Polli, James

    1. You have access
      In Vivo Magnetic Resonance Imaging to Detect Biliary Excretion of 19F-Labeled Drug in Mice
      Jean-Pierre Raufman, Su Xu, Kunrong Cheng, Sandeep Khurana, Diana Johnson, Changxing Shao, Maureen A. Kane, Da Shi, Rao Gullapalli and James Polli
      Drug Metabolism and Disposition May 2011, 39 (5) 736-739; DOI: https://doi.org/10.1124/dmd.110.037358
  4. Pursley, Janice

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341

R

  1. Raufman, Jean-Pierre

    1. You have access
      In Vivo Magnetic Resonance Imaging to Detect Biliary Excretion of 19F-Labeled Drug in Mice
      Jean-Pierre Raufman, Su Xu, Kunrong Cheng, Sandeep Khurana, Diana Johnson, Changxing Shao, Maureen A. Kane, Da Shi, Rao Gullapalli and James Polli
      Drug Metabolism and Disposition May 2011, 39 (5) 736-739; DOI: https://doi.org/10.1124/dmd.110.037358
  2. Rener, Gregory A.

    1. You have access
      Metabolism of LY654322, a Growth Hormone Secretagogue, to an Unusual Diimidazopyridine Metabolite
      Anthony G. Borel, Timothy M. Jones, Robert J. Barbuch, David A. Jackson, Palaniappan Kulanthaivel, Edward Mattiuz, Valentine J. Klimkowski, William J. Wheeler and Gregory A. Rener
      Drug Metabolism and Disposition May 2011, 39 (5) 740-749; DOI: https://doi.org/10.1124/dmd.110.037598
  3. Roth, Megan

    1. You have access
      Interactions of Green Tea Catechins with Organic Anion-Transporting Polypeptides
      Megan Roth, Barbara N. Timmermann and Bruno Hagenbuch
      Drug Metabolism and Disposition May 2011, 39 (5) 920-926; DOI: https://doi.org/10.1124/dmd.110.036640

S

  1. Sakaki, Toshiyuki

    1. You have access
      Metabolism of the c-Fos/Activator Protein-1 Inhibitor T-5224 by Multiple Human UDP-Glucuronosyltransferase Isoforms
      Shinsuke Uchihashi, Hiroyuki Fukumoto, Makoto Onoda, Hiroyoshi Hayakawa, Shin-ichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition May 2011, 39 (5) 803-813; DOI: https://doi.org/10.1124/dmd.110.037952
  2. Sampson, Kathleen E.

    1. You have access
      Pharmacokinetic Interaction of the Antiparasitic Agents Ivermectin and Spinosad in Dogs
      Stewart T. Dunn, Laura Hedges, Kathleen E. Sampson, Yurong Lai, Sean Mahabir, Larissa Balogh and Charles W. Locuson
      Drug Metabolism and Disposition May 2011, 39 (5) 789-795; DOI: https://doi.org/10.1124/dmd.110.034827
  3. Sasaki, Yasutsuna

    1. You have access
      Sorafenib and Sunitinib, Two Anticancer Drugs, Inhibit CYP3A4-Mediated and Activate CY3A5-Mediated Midazolam 1′-Hydroxylation
      Minako Sugiyama, Ken-ichi Fujita, Norie Murayama, Yuko Akiyama, Hiroshi Yamazaki and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2011, 39 (5) 757-762; DOI: https://doi.org/10.1124/dmd.110.037853
  4. Schinkel, Alfred H.

    1. You have access
      Differential Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) on Axitinib Brain Accumulation and Oral Plasma Pharmacokinetics
      Birk Poller, Dilek Iusuf, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
      Drug Metabolism and Disposition May 2011, 39 (5) 729-735; DOI: https://doi.org/10.1124/dmd.110.037317
  5. Shao, Changxing

    1. You have access
      In Vivo Magnetic Resonance Imaging to Detect Biliary Excretion of 19F-Labeled Drug in Mice
      Jean-Pierre Raufman, Su Xu, Kunrong Cheng, Sandeep Khurana, Diana Johnson, Changxing Shao, Maureen A. Kane, Da Shi, Rao Gullapalli and James Polli
      Drug Metabolism and Disposition May 2011, 39 (5) 736-739; DOI: https://doi.org/10.1124/dmd.110.037358
  6. Shi, Da

    1. You have access
      In Vivo Magnetic Resonance Imaging to Detect Biliary Excretion of 19F-Labeled Drug in Mice
      Jean-Pierre Raufman, Su Xu, Kunrong Cheng, Sandeep Khurana, Diana Johnson, Changxing Shao, Maureen A. Kane, Da Shi, Rao Gullapalli and James Polli
      Drug Metabolism and Disposition May 2011, 39 (5) 736-739; DOI: https://doi.org/10.1124/dmd.110.037358
  7. Sjögren, Erik

    1. You have access
      Optimal Experimental Design for Assessment of Enzyme Kinetics in a Drug Discovery Screening Environment
      Erik Sjögren, Joakim Nyberg, Mats O. Magnusson, Hans Lennernäs, Andrew Hooker and Ulf Bredberg
      Drug Metabolism and Disposition May 2011, 39 (5) 858-863; DOI: https://doi.org/10.1124/dmd.110.037309
  8. Snider, Natasha T.

    1. You have access
      Anandamide Oxidation by Wild-Type and Polymorphically Expressed CYP2B6 and CYP2D6
      Chitra Sridar, Natasha T. Snider and Paul F. Hollenberg
      Drug Metabolism and Disposition May 2011, 39 (5) 782-788; DOI: https://doi.org/10.1124/dmd.110.036707
  9. Sparidans, Rolf W.

    1. You have access
      Differential Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) on Axitinib Brain Accumulation and Oral Plasma Pharmacokinetics
      Birk Poller, Dilek Iusuf, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
      Drug Metabolism and Disposition May 2011, 39 (5) 729-735; DOI: https://doi.org/10.1124/dmd.110.037317
  10. Sridar, Chitra

    1. You have access
      Anandamide Oxidation by Wild-Type and Polymorphically Expressed CYP2B6 and CYP2D6
      Chitra Sridar, Natasha T. Snider and Paul F. Hollenberg
      Drug Metabolism and Disposition May 2011, 39 (5) 782-788; DOI: https://doi.org/10.1124/dmd.110.036707
  11. Stingl, Julia C.

    1. You have access
      Effect of the CYP2C8 Genotype on the Pharmacokinetics and Pharmacodynamics of Repaglinide
      Dorota Tomalik-Scharte, Uwe Fuhr, Martin Hellmich, Dorothee Frank, Oxana Doroshyenko, Alexander Jetter and Julia C. Stingl
      Drug Metabolism and Disposition May 2011, 39 (5) 927-932; DOI: https://doi.org/10.1124/dmd.110.036921
  12. Sugamori, Kim S.

    1. You have access
      Liver-Selective Expression of Human Arylamine N-Acetyltransferase NAT2 in Transgenic Mice
      Kim S. Sugamori, Debbie Brenneman and Denis M. Grant
      Drug Metabolism and Disposition May 2011, 39 (5) 882-890; DOI: https://doi.org/10.1124/dmd.111.038216
  13. Sugiyama, Minako

    1. You have access
      Sorafenib and Sunitinib, Two Anticancer Drugs, Inhibit CYP3A4-Mediated and Activate CY3A5-Mediated Midazolam 1′-Hydroxylation
      Minako Sugiyama, Ken-ichi Fujita, Norie Murayama, Yuko Akiyama, Hiroshi Yamazaki and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2011, 39 (5) 757-762; DOI: https://doi.org/10.1124/dmd.110.037853
  14. Sugiyama, Yuichi

    1. You have access
      Organic Anion Transporter 3 Mediates the Efflux Transport of an Amphipathic Organic Anion, Dehydroepiandrosterone Sulfate, across the Blood-Brain Barrier in Mice
      Mari Miyajima, Hiroyuki Kusuhara, Miki Fujishima, Yasuhisa Adachi and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2011, 39 (5) 814-819; DOI: https://doi.org/10.1124/dmd.110.036863
  15. Suzuki, Norio

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457

T

  1. Thakur, Ashish

    1. You have access
      Influence of Drug Solubility and Lipophilicity on Transscleral Retinal Delivery of Six Corticosteroids
      Ashish Thakur, Rajendra S. Kadam and Uday B. Kompella
      Drug Metabolism and Disposition May 2011, 39 (5) 771-781; DOI: https://doi.org/10.1124/dmd.110.037408
  2. Timmermann, Barbara N.

    1. You have access
      Interactions of Green Tea Catechins with Organic Anion-Transporting Polypeptides
      Megan Roth, Barbara N. Timmermann and Bruno Hagenbuch
      Drug Metabolism and Disposition May 2011, 39 (5) 920-926; DOI: https://doi.org/10.1124/dmd.110.036640
  3. Tomalik-Scharte, Dorota

    1. You have access
      Effect of the CYP2C8 Genotype on the Pharmacokinetics and Pharmacodynamics of Repaglinide
      Dorota Tomalik-Scharte, Uwe Fuhr, Martin Hellmich, Dorothee Frank, Oxana Doroshyenko, Alexander Jetter and Julia C. Stingl
      Drug Metabolism and Disposition May 2011, 39 (5) 927-932; DOI: https://doi.org/10.1124/dmd.110.036921
  4. Tran, Scott B.

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341

U

  1. Uchihashi, Shinsuke

    1. You have access
      Metabolism of the c-Fos/Activator Protein-1 Inhibitor T-5224 by Multiple Human UDP-Glucuronosyltransferase Isoforms
      Shinsuke Uchihashi, Hiroyuki Fukumoto, Makoto Onoda, Hiroyoshi Hayakawa, Shin-ichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition May 2011, 39 (5) 803-813; DOI: https://doi.org/10.1124/dmd.110.037952

V

  1. Vallejo, Jesus G.

    1. You have access
      Differential Role of Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein in Toll-Like Receptor 2-Mediated Regulation of Gene Expression of Hepatic Cytokines and Drug-Metabolizing Enzymes
      Romi Ghose, Tao Guo, Jesus G. Vallejo and Adarsh Gandhi
      Drug Metabolism and Disposition May 2011, 39 (5) 874-881; DOI: https://doi.org/10.1124/dmd.110.037382
  2. van der Vijgh, Wim J. F.

    1. You have access
      Identification of the Metabolites of the Antioxidant Flavonoid 7-Mono-O-(β-hydroxyethyl)-rutoside in Mice
      Hilde Jacobs, Ron Peters, Gertjan J. M. den Hartog, Wim J. F. van der Vijgh, Aalt Bast and Guido R. M. M. Haenen
      Drug Metabolism and Disposition May 2011, 39 (5) 750-756; DOI: https://doi.org/10.1124/dmd.110.036525

W

  1. Wagenaar, Els

    1. You have access
      Differential Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) on Axitinib Brain Accumulation and Oral Plasma Pharmacokinetics
      Birk Poller, Dilek Iusuf, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
      Drug Metabolism and Disposition May 2011, 39 (5) 729-735; DOI: https://doi.org/10.1124/dmd.110.037317
  2. Wang, Hao

    1. You have access
      Evaluation of the Effects of 20 Nonsynonymous Single Nucleotide Polymorphisms of CYP2C19 on S-Mephenytoin 4′-Hydroxylation and Omeprazole 5′-Hydroxylation
      Huijuan Wang, Nianzhen An, Hao Wang, Yiwen Gao, Duan Liu, Ting Bian, Juanli Zhu and Chao Chen
      Drug Metabolism and Disposition May 2011, 39 (5) 830-837; DOI: https://doi.org/10.1124/dmd.110.037549
  3. Wang, Huijuan

    1. You have access
      Evaluation of the Effects of 20 Nonsynonymous Single Nucleotide Polymorphisms of CYP2C19 on S-Mephenytoin 4′-Hydroxylation and Omeprazole 5′-Hydroxylation
      Huijuan Wang, Nianzhen An, Hao Wang, Yiwen Gao, Duan Liu, Ting Bian, Juanli Zhu and Chao Chen
      Drug Metabolism and Disposition May 2011, 39 (5) 830-837; DOI: https://doi.org/10.1124/dmd.110.037549
  4. Wang, Yiping

    1. You have access
      Contribution of Carboxylesterase in Hamster to the Intestinal First-Pass Loss and Low Bioavailability of Ethyl Piperate, an Effective Lipid-Lowering Drug Candidate
      Youli Lu, Narisu Bao, Gereltu Borjihan, Yanling Ma, Miaomiao Hu, Chen Yu, Shuijun Li, Jingying Jia, Ding Yang and Yiping Wang
      Drug Metabolism and Disposition May 2011, 39 (5) 796-802; DOI: https://doi.org/10.1124/dmd.110.037614
  5. Watanabe, Nobuaki

    1. You have access
      Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up Approach
      Tsuneo Deguchi, Nobuaki Watanabe, Atsushi Kurihara, Katsuhiro Igeta, Hidenori Ikenaga, Keiichi Fusegawa, Norio Suzuki, Shinji Murata, Masakazu Hirouchi, Yoshitake Furuta, Masaru Iwasaki, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition May 2011, 39 (5) 820-829; DOI: https://doi.org/10.1124/dmd.110.037457
  6. Wheeler, William J.

    1. You have access
      Metabolism of LY654322, a Growth Hormone Secretagogue, to an Unusual Diimidazopyridine Metabolite
      Anthony G. Borel, Timothy M. Jones, Robert J. Barbuch, David A. Jackson, Palaniappan Kulanthaivel, Edward Mattiuz, Valentine J. Klimkowski, William J. Wheeler and Gregory A. Rener
      Drug Metabolism and Disposition May 2011, 39 (5) 740-749; DOI: https://doi.org/10.1124/dmd.110.037598
  7. Williams, Daphne

    1. You have access
      Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
      Jiachang Gong, Jinping Gan, Janet Caceres-Cortes, Lisa J. Christopher, Vinod Arora, Eric Masson, Daphne Williams, Janice Pursley, Alban Allentoff, Michael Lago, Scott B. Tran and Ramaswamy A. Iyer
      Drug Metabolism and Disposition May 2011, 39 (5) 891-903; DOI: https://doi.org/10.1124/dmd.110.037341

X

  1. Xu, Su

    1. You have access
      In Vivo Magnetic Resonance Imaging to Detect Biliary Excretion of 19F-Labeled Drug in Mice
      Jean-Pierre Raufman, Su Xu, Kunrong Cheng, Sandeep Khurana, Diana Johnson, Changxing Shao, Maureen A. Kane, Da Shi, Rao Gullapalli and James Polli
      Drug Metabolism and Disposition May 2011, 39 (5) 736-739; DOI: https://doi.org/10.1124/dmd.110.037358

Y

  1. Yamazaki, Hiroshi

    1. You have access
      Sorafenib and Sunitinib, Two Anticancer Drugs, Inhibit CYP3A4-Mediated and Activate CY3A5-Mediated Midazolam 1′-Hydroxylation
      Minako Sugiyama, Ken-ichi Fujita, Norie Murayama, Yuko Akiyama, Hiroshi Yamazaki and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2011, 39 (5) 757-762; DOI: https://doi.org/10.1124/dmd.110.037853
  2. Yang, Ding

    1. You have access
      Contribution of Carboxylesterase in Hamster to the Intestinal First-Pass Loss and Low Bioavailability of Ethyl Piperate, an Effective Lipid-Lowering Drug Candidate
      Youli Lu, Narisu Bao, Gereltu Borjihan, Yanling Ma, Miaomiao Hu, Chen Yu, Shuijun Li, Jingying Jia, Ding Yang and Yiping Wang
      Drug Metabolism and Disposition May 2011, 39 (5) 796-802; DOI: https://doi.org/10.1124/dmd.110.037614
  3. Yokoi, Tsuyoshi

    1. You have access
      CYP2C9-Mediated Metabolic Activation of Losartan Detected by a Highly Sensitive Cell-Based Screening Assay
      Atsushi Iwamura, Tatsuki Fukami, Hiroko Hosomi, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition May 2011, 39 (5) 838-846; DOI: https://doi.org/10.1124/dmd.110.037259
  4. Yu, Chen

    1. You have access
      Contribution of Carboxylesterase in Hamster to the Intestinal First-Pass Loss and Low Bioavailability of Ethyl Piperate, an Effective Lipid-Lowering Drug Candidate
      Youli Lu, Narisu Bao, Gereltu Borjihan, Yanling Ma, Miaomiao Hu, Chen Yu, Shuijun Li, Jingying Jia, Ding Yang and Yiping Wang
      Drug Metabolism and Disposition May 2011, 39 (5) 796-802; DOI: https://doi.org/10.1124/dmd.110.037614

Z

  1. Zhu, Juanli

    1. You have access
      Evaluation of the Effects of 20 Nonsynonymous Single Nucleotide Polymorphisms of CYP2C19 on S-Mephenytoin 4′-Hydroxylation and Omeprazole 5′-Hydroxylation
      Huijuan Wang, Nianzhen An, Hao Wang, Yiwen Gao, Duan Liu, Ting Bian, Juanli Zhu and Chao Chen
      Drug Metabolism and Disposition May 2011, 39 (5) 830-837; DOI: https://doi.org/10.1124/dmd.110.037549
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Drug Metabolism and Disposition: 39 (5)
Drug Metabolism and Disposition
Vol. 39, Issue 5
1 May 2011
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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