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Research ArticleArticle

Complex Drug Interactions of HIV Protease Inhibitors 1: Inactivation, Induction, and Inhibition of Cytochrome P450 3A by Ritonavir or Nelfinavir

Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
Drug Metabolism and Disposition June 2011, 39 (6) 1070-1078; DOI: https://doi.org/10.1124/dmd.110.037523

Article Information

vol. 39 no. 6 1070-1078
DOI 
https://doi.org/10.1124/dmd.110.037523
PubMed 
21406602
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received December 3, 2010
  • Accepted March 9, 2011
  • Published online May 16, 2011.

Article Versions

Copyright & Usage 
Copyright © 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Brian J. Kirby,
  2. Ann C. Collier,
  3. Evan D. Kharasch,
  4. Dale Whittington,
  5. Kenneth E. Thummel and
  6. Jashvant D. Unadkat
  1. Departments of Pharmaceutics (B.J.K., D.W., K.E.T., J.D.U.) and Medicine (A.C.C.), University of Washington, Seattle Washington; and Department of Anesthesiology, Washington University, St. Louis, Missouri (E.D.K.)
  1. Address correspondence to:
    Dr. Jashvant D. Unadkat, Department of Pharmaceutics, School of Pharmacy, Box 357610, University of Washington, Seattle WA 98195-7610. E-mail: jash{at}u.washington.edu
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Research ArticleArticle

Complex Drug Interactions of HIV Protease Inhibitors 1: Inactivation, Induction, and Inhibition of Cytochrome P450 3A by Ritonavir or Nelfinavir

Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
Drug Metabolism and Disposition June 1, 2011, 39 (6) 1070-1078; DOI: https://doi.org/10.1124/dmd.110.037523
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