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Drug Metabolism & Disposition

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    • Current Issue
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Index by author

July 01, 2011; Volume 39,Issue 7
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Andersson, Tommy B.

    1. You have access
      Cytochrome P450-Dependent Metabolism in HepaRG Cells Cultured in a Dynamic Three-Dimensional Bioreactor
      Malin Darnell, Thomas Schreiter, Katrin Zeilinger, Thomas Urbaniak, Therese Söderdahl, Ingrid Rossberg, Birgitta Dillnér, Anna-Lena Berg, Jörg C. Gerlach and Tommy B. Andersson
      Drug Metabolism and Disposition July 2011, 39 (7) 1131-1138; DOI: https://doi.org/10.1124/dmd.110.037721
  2. Aso, Yoshinori

    1. You have access
      Quantitative Prediction of Mechanism-Based Inhibition Caused by Mibefradil in Rats
      Nobuo Sekiguchi, Motohiro Kato, Maiko Takada, Hiroo Watanabe, Shotaro Takata, Tetsuya Mitsui, Yoshinori Aso and Masaki Ishigai
      Drug Metabolism and Disposition July 2011, 39 (7) 1255-1262; DOI: https://doi.org/10.1124/dmd.110.037903

B

  1. Berg, Anna-Lena

    1. You have access
      Cytochrome P450-Dependent Metabolism in HepaRG Cells Cultured in a Dynamic Three-Dimensional Bioreactor
      Malin Darnell, Thomas Schreiter, Katrin Zeilinger, Thomas Urbaniak, Therese Söderdahl, Ingrid Rossberg, Birgitta Dillnér, Anna-Lena Berg, Jörg C. Gerlach and Tommy B. Andersson
      Drug Metabolism and Disposition July 2011, 39 (7) 1131-1138; DOI: https://doi.org/10.1124/dmd.110.037721
  2. Boado, Ruben J.

    1. You have access
      Chronic Dosing of Mice with a Transferrin Receptor Monoclonal Antibody-Glial-Derived Neurotrophic Factor Fusion Protein
      Qing-Hui Zhou, Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition July 2011, 39 (7) 1149-1154; DOI: https://doi.org/10.1124/dmd.111.038349
  3. Bode, Chris

    1. You have access
      Use of Transporter Knockdown Caco-2 Cells to Investigate the In Vitro Efflux of Statin Drugs
      Jibin Li, Donna A. Volpe, Ying Wang, Wei Zhang, Chris Bode, Albert Owen and Ismael J. Hidalgo
      Drug Metabolism and Disposition July 2011, 39 (7) 1196-1202; DOI: https://doi.org/10.1124/dmd.111.038075
  4. Bowersox, S. Scott

    1. You have access
      Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders
      S. Scott Bowersox, Luke K. Lightning, Satish Rao, Monica Palme, Dave Ellis, Renee Coleman, Adrian M. Davies, Padmapriya Kumaraswamy and Pascal Druzgala
      Drug Metabolism and Disposition July 2011, 39 (7) 1170-1180; DOI: https://doi.org/10.1124/dmd.110.037564

C

  1. Caron, Patrick

    1. You have access
      In Vitro Investigation of Human UDP-Glucuronosyltransferase Isoforms Responsible for Tacrolimus Glucuronidation: Predominant Contribution of UGT1A4
      Isabelle Laverdière, Patrick Caron, Mario Harvey, Éric Lévesque and Chantal Guillemette
      Drug Metabolism and Disposition July 2011, 39 (7) 1127-1130; DOI: https://doi.org/10.1124/dmd.111.039040
  2. Celma, Carles

    1. You have access
      In Vitro Metabolism of Irosustat, a Novel Steroid Sulfatase Inhibitor: Interspecies Comparison, Metabolite Identification, and Metabolic Enzyme Identification
      Verònica Ventura, Josep Solà, Carles Celma, Concepción Peraire and Rosendo Obach
      Drug Metabolism and Disposition July 2011, 39 (7) 1235-1246; DOI: https://doi.org/10.1124/dmd.111.038315
  3. Chang, George

    1. You have access
      Species Independence in Brain Tissue Binding Using Brain Homogenates
      Li Di, John P. Umland, George Chang, Youping Huang, Zhen Lin, Dennis O. Scott, Matthew D. Troutman and Theodore E. Liston
      Drug Metabolism and Disposition July 2011, 39 (7) 1270-1277; DOI: https://doi.org/10.1124/dmd.111.038778
  4. Cheatham, Steve F.

    1. You have access
      Comparative Metabolism of 1,2,3,3,3-Pentafluoropropene in Male and Female Mouse, Rat, Dog, and Human Liver Microsomes and Cytosol and Male Rat Hepatocytes via Oxidative Dehalogenation and Glutathione S-Conjugation Pathways
      Xing Han, Bogdan Szostek, Ching-Hui Yang, Steve F. Cheatham, Robert T. Mingoia, Diane L. Nabb, Shawn A. Gannon, Matthew W. Himmelstein and Gary W. Jepson
      Drug Metabolism and Disposition July 2011, 39 (7) 1288-1293; DOI: https://doi.org/10.1124/dmd.111.038299
  5. Coleman, Renee

    1. You have access
      Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders
      S. Scott Bowersox, Luke K. Lightning, Satish Rao, Monica Palme, Dave Ellis, Renee Coleman, Adrian M. Davies, Padmapriya Kumaraswamy and Pascal Druzgala
      Drug Metabolism and Disposition July 2011, 39 (7) 1170-1180; DOI: https://doi.org/10.1124/dmd.110.037564

D

  1. Danhof, Meindert

    1. You have access
      A Semiphysiological Population Model for Prediction of the Pharmacokinetics of Drugs under Liver and Renal Disease Conditions
      Ashley Strougo, Ashraf Yassen, Walter Krauwinkel, Meindert Danhof and Jan Freijer
      Drug Metabolism and Disposition July 2011, 39 (7) 1278-1287; DOI: https://doi.org/10.1124/dmd.110.037838
  2. Darnell, Malin

    1. You have access
      Cytochrome P450-Dependent Metabolism in HepaRG Cells Cultured in a Dynamic Three-Dimensional Bioreactor
      Malin Darnell, Thomas Schreiter, Katrin Zeilinger, Thomas Urbaniak, Therese Söderdahl, Ingrid Rossberg, Birgitta Dillnér, Anna-Lena Berg, Jörg C. Gerlach and Tommy B. Andersson
      Drug Metabolism and Disposition July 2011, 39 (7) 1131-1138; DOI: https://doi.org/10.1124/dmd.110.037721
  3. Davies, Adrian M.

    1. You have access
      Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders
      S. Scott Bowersox, Luke K. Lightning, Satish Rao, Monica Palme, Dave Ellis, Renee Coleman, Adrian M. Davies, Padmapriya Kumaraswamy and Pascal Druzgala
      Drug Metabolism and Disposition July 2011, 39 (7) 1170-1180; DOI: https://doi.org/10.1124/dmd.110.037564
  4. Davis, John

    1. You have access
      Application of Physiologically Based Pharmacokinetic Modeling to Understanding the Clinical Pharmacokinetics of UK-369,003
      Kenny J. Watson, John Davis and Hannah M. Jones
      Drug Metabolism and Disposition July 2011, 39 (7) 1203-1213; DOI: https://doi.org/10.1124/dmd.111.038224
  5. Delzer, Juergen

    1. You have access
      Disposition and Drug-Drug Interaction Potential of Veliparib (ABT-888), a Novel and Potent Inhibitor of Poly(ADP-ribose) Polymerase
      Xiaofeng Li, Juergen Delzer, Richard Voorman, Sonia M. de Morais and Yanbin Lao
      Drug Metabolism and Disposition July 2011, 39 (7) 1161-1169; DOI: https://doi.org/10.1124/dmd.110.037820
  6. de Morais, Sonia M.

    1. You have access
      Disposition and Drug-Drug Interaction Potential of Veliparib (ABT-888), a Novel and Potent Inhibitor of Poly(ADP-ribose) Polymerase
      Xiaofeng Li, Juergen Delzer, Richard Voorman, Sonia M. de Morais and Yanbin Lao
      Drug Metabolism and Disposition July 2011, 39 (7) 1161-1169; DOI: https://doi.org/10.1124/dmd.110.037820
  7. Di, Li

    1. You have access
      Species Independence in Brain Tissue Binding Using Brain Homogenates
      Li Di, John P. Umland, George Chang, Youping Huang, Zhen Lin, Dennis O. Scott, Matthew D. Troutman and Theodore E. Liston
      Drug Metabolism and Disposition July 2011, 39 (7) 1270-1277; DOI: https://doi.org/10.1124/dmd.111.038778
  8. Dillnér, Birgitta

    1. You have access
      Cytochrome P450-Dependent Metabolism in HepaRG Cells Cultured in a Dynamic Three-Dimensional Bioreactor
      Malin Darnell, Thomas Schreiter, Katrin Zeilinger, Thomas Urbaniak, Therese Söderdahl, Ingrid Rossberg, Birgitta Dillnér, Anna-Lena Berg, Jörg C. Gerlach and Tommy B. Andersson
      Drug Metabolism and Disposition July 2011, 39 (7) 1131-1138; DOI: https://doi.org/10.1124/dmd.110.037721
  9. Dinter-Heidorn, Heike

    1. You have access
      Cannabinoid Type 1 Receptor Antagonists Modulate Transport Activity of Multidrug Resistance-Associated Proteins MRP1, MRP2, MRP3, and MRP4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Heike Dinter-Heidorn, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition July 2011, 39 (7) 1294-1302; DOI: https://doi.org/10.1124/dmd.110.037812
  10. Druzgala, Pascal

    1. You have access
      Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders
      S. Scott Bowersox, Luke K. Lightning, Satish Rao, Monica Palme, Dave Ellis, Renee Coleman, Adrian M. Davies, Padmapriya Kumaraswamy and Pascal Druzgala
      Drug Metabolism and Disposition July 2011, 39 (7) 1170-1180; DOI: https://doi.org/10.1124/dmd.110.037564
  11. Duran, Marinus

    1. You have access
      Role of Isovaleryl-CoA Dehydrogenase and Short Branched-Chain Acyl-CoA Dehydrogenase in the Metabolism of Valproic Acid: Implications for the Branched-Chain Amino Acid Oxidation Pathway
      Paula B. M. Luís, Jos P. N. Ruiter, Lodewijk IJlst, Isabel Tavares de Almeida, Marinus Duran, Al-Walid Mohsen, Jerry Vockley, Ronald J. A. Wanders and Margarida F. B. Silva
      Drug Metabolism and Disposition July 2011, 39 (7) 1155-1160; DOI: https://doi.org/10.1124/dmd.110.037606

E

  1. Ellis, Dave

    1. You have access
      Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders
      S. Scott Bowersox, Luke K. Lightning, Satish Rao, Monica Palme, Dave Ellis, Renee Coleman, Adrian M. Davies, Padmapriya Kumaraswamy and Pascal Druzgala
      Drug Metabolism and Disposition July 2011, 39 (7) 1170-1180; DOI: https://doi.org/10.1124/dmd.110.037564

F

  1. Fischer, Thomas

    1. You have access
      In Vitro Metabolism of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rat, Monkey, and Human Liver Microsomes and Freshly Isolated Hepatocytes
      Minoru Uchiyama, Hiroko Koda, Thomas Fischer, Juergen Mueller, Naotoshi Yamamura, Minoru Oguchi, Haruo Iwabuchi, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition July 2011, 39 (7) 1311-1319; DOI: https://doi.org/10.1124/dmd.111.038729
  2. Foti, Robert S.

    1. You have access
      Mechanism-Based Inactivation of Cytochrome P450 3A4 by Mibefradil through Heme Destruction
      Robert S. Foti, Dan A. Rock, Josh T. Pearson, Jan L. Wahlstrom and Larry C. Wienkers
      Drug Metabolism and Disposition July 2011, 39 (7) 1188-1195; DOI: https://doi.org/10.1124/dmd.111.038505
  3. Freijer, Jan

    1. You have access
      A Semiphysiological Population Model for Prediction of the Pharmacokinetics of Drugs under Liver and Renal Disease Conditions
      Ashley Strougo, Ashraf Yassen, Walter Krauwinkel, Meindert Danhof and Jan Freijer
      Drug Metabolism and Disposition July 2011, 39 (7) 1278-1287; DOI: https://doi.org/10.1124/dmd.110.037838

G

  1. Gannon, Shawn A.

    1. You have access
      Comparative Metabolism of 1,2,3,3,3-Pentafluoropropene in Male and Female Mouse, Rat, Dog, and Human Liver Microsomes and Cytosol and Male Rat Hepatocytes via Oxidative Dehalogenation and Glutathione S-Conjugation Pathways
      Xing Han, Bogdan Szostek, Ching-Hui Yang, Steve F. Cheatham, Robert T. Mingoia, Diane L. Nabb, Shawn A. Gannon, Matthew W. Himmelstein and Gary W. Jepson
      Drug Metabolism and Disposition July 2011, 39 (7) 1288-1293; DOI: https://doi.org/10.1124/dmd.111.038299
  2. Gerlach, Jörg C.

    1. You have access
      Cytochrome P450-Dependent Metabolism in HepaRG Cells Cultured in a Dynamic Three-Dimensional Bioreactor
      Malin Darnell, Thomas Schreiter, Katrin Zeilinger, Thomas Urbaniak, Therese Söderdahl, Ingrid Rossberg, Birgitta Dillnér, Anna-Lena Berg, Jörg C. Gerlach and Tommy B. Andersson
      Drug Metabolism and Disposition July 2011, 39 (7) 1131-1138; DOI: https://doi.org/10.1124/dmd.110.037721
  3. Guillemette, Chantal

    1. You have access
      In Vitro Investigation of Human UDP-Glucuronosyltransferase Isoforms Responsible for Tacrolimus Glucuronidation: Predominant Contribution of UGT1A4
      Isabelle Laverdière, Patrick Caron, Mario Harvey, Éric Lévesque and Chantal Guillemette
      Drug Metabolism and Disposition July 2011, 39 (7) 1127-1130; DOI: https://doi.org/10.1124/dmd.111.039040

H

  1. Halpert, James R.

    1. You have access
      Structure and Function of Cytochromes P450 2B: From Mechanism-Based Inactivators to X-Ray Crystal Structures and Back
      James R. Halpert
      Drug Metabolism and Disposition July 2011, 39 (7) 1113-1121; DOI: https://doi.org/10.1124/dmd.111.039719
  2. Han, Xing

    1. You have access
      Comparative Metabolism of 1,2,3,3,3-Pentafluoropropene in Male and Female Mouse, Rat, Dog, and Human Liver Microsomes and Cytosol and Male Rat Hepatocytes via Oxidative Dehalogenation and Glutathione S-Conjugation Pathways
      Xing Han, Bogdan Szostek, Ching-Hui Yang, Steve F. Cheatham, Robert T. Mingoia, Diane L. Nabb, Shawn A. Gannon, Matthew W. Himmelstein and Gary W. Jepson
      Drug Metabolism and Disposition July 2011, 39 (7) 1288-1293; DOI: https://doi.org/10.1124/dmd.111.038299
  3. Harvey, Mario

    1. You have access
      In Vitro Investigation of Human UDP-Glucuronosyltransferase Isoforms Responsible for Tacrolimus Glucuronidation: Predominant Contribution of UGT1A4
      Isabelle Laverdière, Patrick Caron, Mario Harvey, Éric Lévesque and Chantal Guillemette
      Drug Metabolism and Disposition July 2011, 39 (7) 1127-1130; DOI: https://doi.org/10.1124/dmd.111.039040
  4. Hashizume, Takanori

    1. You have access
      In Vitro Investigation of the Glutathione Transferase M1 and T1 Null Genotypes as Risk Factors for Troglitazone-Induced Liver Injury
      Toru Usui, Takanori Hashizume, Takashi Katsumata, Tsuyoshi Yokoi and Setsuko Komuro
      Drug Metabolism and Disposition July 2011, 39 (7) 1303-1310; DOI: https://doi.org/10.1124/dmd.111.038661
  5. Hayashi, Mike

    1. You have access
      Simulation of Clinical Drug-Drug Interactions from Hepatocyte CYP3A4 Induction Data and Its Potential Utility in Trial Designs
      Yang Xu, Yihong Zhou, Mike Hayashi, Magang Shou and Gary L. Skiles
      Drug Metabolism and Disposition July 2011, 39 (7) 1139-1148; DOI: https://doi.org/10.1124/dmd.111.038067
  6. Hidalgo, Ismael J.

    1. You have access
      Use of Transporter Knockdown Caco-2 Cells to Investigate the In Vitro Efflux of Statin Drugs
      Jibin Li, Donna A. Volpe, Ying Wang, Wei Zhang, Chris Bode, Albert Owen and Ismael J. Hidalgo
      Drug Metabolism and Disposition July 2011, 39 (7) 1196-1202; DOI: https://doi.org/10.1124/dmd.111.038075
  7. Himmelstein, Matthew W.

    1. You have access
      Comparative Metabolism of 1,2,3,3,3-Pentafluoropropene in Male and Female Mouse, Rat, Dog, and Human Liver Microsomes and Cytosol and Male Rat Hepatocytes via Oxidative Dehalogenation and Glutathione S-Conjugation Pathways
      Xing Han, Bogdan Szostek, Ching-Hui Yang, Steve F. Cheatham, Robert T. Mingoia, Diane L. Nabb, Shawn A. Gannon, Matthew W. Himmelstein and Gary W. Jepson
      Drug Metabolism and Disposition July 2011, 39 (7) 1288-1293; DOI: https://doi.org/10.1124/dmd.111.038299
  8. Honda, Kokichi

    1. You have access
      Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites
      Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe, Yoshihiro Miyaji, Wataru Suzuki, Daisuke Sugiyama, Kazuhito Shiosakai, Kokichi Honda, Noriko Okudaira, Takashi Izumi and Osamu Okazaki
      Drug Metabolism and Disposition July 2011, 39 (7) 1247-1254; DOI: https://doi.org/10.1124/dmd.111.039180
  9. Hough, Lindsay B.

    1. You have access
      Effects of Acetylenic Epoxygenase Inhibitors on Recombinant Cytochrome P450s
      Melissa A. VanAlstine and Lindsay B. Hough
      Drug Metabolism and Disposition July 2011, 39 (7) 1221-1226; DOI: https://doi.org/10.1124/dmd.110.037424
  10. Huang, Youping

    1. You have access
      Species Independence in Brain Tissue Binding Using Brain Homogenates
      Li Di, John P. Umland, George Chang, Youping Huang, Zhen Lin, Dennis O. Scott, Matthew D. Troutman and Theodore E. Liston
      Drug Metabolism and Disposition July 2011, 39 (7) 1270-1277; DOI: https://doi.org/10.1124/dmd.111.038778
  11. Hui, Eric Ka-Wai

    1. You have access
      Chronic Dosing of Mice with a Transferrin Receptor Monoclonal Antibody-Glial-Derived Neurotrophic Factor Fusion Protein
      Qing-Hui Zhou, Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition July 2011, 39 (7) 1149-1154; DOI: https://doi.org/10.1124/dmd.111.038349

I

  1. IJlst, Lodewijk

    1. You have access
      Role of Isovaleryl-CoA Dehydrogenase and Short Branched-Chain Acyl-CoA Dehydrogenase in the Metabolism of Valproic Acid: Implications for the Branched-Chain Amino Acid Oxidation Pathway
      Paula B. M. Luís, Jos P. N. Ruiter, Lodewijk IJlst, Isabel Tavares de Almeida, Marinus Duran, Al-Walid Mohsen, Jerry Vockley, Ronald J. A. Wanders and Margarida F. B. Silva
      Drug Metabolism and Disposition July 2011, 39 (7) 1155-1160; DOI: https://doi.org/10.1124/dmd.110.037606
  2. Imai, Teruko

    1. You have access
      Prediction of Human Intestinal Absorption of the Prodrug Temocapril by In Situ Single-Pass Perfusion Using Rat Intestine with Modified Hydrolase Activity
      Takaaki Nozawa and Teruko Imai
      Drug Metabolism and Disposition July 2011, 39 (7) 1263-1269; DOI: https://doi.org/10.1124/dmd.110.037937
  3. Ishigai, Masaki

    1. You have access
      Quantitative Prediction of Mechanism-Based Inhibition Caused by Mibefradil in Rats
      Nobuo Sekiguchi, Motohiro Kato, Maiko Takada, Hiroo Watanabe, Shotaro Takata, Tetsuya Mitsui, Yoshinori Aso and Masaki Ishigai
      Drug Metabolism and Disposition July 2011, 39 (7) 1255-1262; DOI: https://doi.org/10.1124/dmd.110.037903
  4. Iwabuchi, Haruo

    1. You have access
      In Vitro Metabolism of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rat, Monkey, and Human Liver Microsomes and Freshly Isolated Hepatocytes
      Minoru Uchiyama, Hiroko Koda, Thomas Fischer, Juergen Mueller, Naotoshi Yamamura, Minoru Oguchi, Haruo Iwabuchi, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition July 2011, 39 (7) 1311-1319; DOI: https://doi.org/10.1124/dmd.111.038729
  5. Izumi, Takashi

    1. You have access
      In Vitro Metabolism of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rat, Monkey, and Human Liver Microsomes and Freshly Isolated Hepatocytes
      Minoru Uchiyama, Hiroko Koda, Thomas Fischer, Juergen Mueller, Naotoshi Yamamura, Minoru Oguchi, Haruo Iwabuchi, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition July 2011, 39 (7) 1311-1319; DOI: https://doi.org/10.1124/dmd.111.038729
    2. You have access
      Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites
      Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe, Yoshihiro Miyaji, Wataru Suzuki, Daisuke Sugiyama, Kazuhito Shiosakai, Kokichi Honda, Noriko Okudaira, Takashi Izumi and Osamu Okazaki
      Drug Metabolism and Disposition July 2011, 39 (7) 1247-1254; DOI: https://doi.org/10.1124/dmd.111.039180

J

  1. Jepson, Gary W.

    1. You have access
      Comparative Metabolism of 1,2,3,3,3-Pentafluoropropene in Male and Female Mouse, Rat, Dog, and Human Liver Microsomes and Cytosol and Male Rat Hepatocytes via Oxidative Dehalogenation and Glutathione S-Conjugation Pathways
      Xing Han, Bogdan Szostek, Ching-Hui Yang, Steve F. Cheatham, Robert T. Mingoia, Diane L. Nabb, Shawn A. Gannon, Matthew W. Himmelstein and Gary W. Jepson
      Drug Metabolism and Disposition July 2011, 39 (7) 1288-1293; DOI: https://doi.org/10.1124/dmd.111.038299
  2. Jiang, Xi-Ling

    1. You have access
      Nonlinear Pharmacokinetics of 5-Methoxy-N,N-dimethyltryptamine in Mice
      Hong-Wu Shen, Xi-Ling Jiang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2011, 39 (7) 1227-1234; DOI: https://doi.org/10.1124/dmd.111.039107
  3. Jones, Hannah M.

    1. You have access
      Application of Physiologically Based Pharmacokinetic Modeling to Understanding the Clinical Pharmacokinetics of UK-369,003
      Kenny J. Watson, John Davis and Hannah M. Jones
      Drug Metabolism and Disposition July 2011, 39 (7) 1203-1213; DOI: https://doi.org/10.1124/dmd.111.038224

K

  1. Kato, Motohiro

    1. You have access
      Quantitative Prediction of Mechanism-Based Inhibition Caused by Mibefradil in Rats
      Nobuo Sekiguchi, Motohiro Kato, Maiko Takada, Hiroo Watanabe, Shotaro Takata, Tetsuya Mitsui, Yoshinori Aso and Masaki Ishigai
      Drug Metabolism and Disposition July 2011, 39 (7) 1255-1262; DOI: https://doi.org/10.1124/dmd.110.037903
  2. Katsumata, Takashi

    1. You have access
      In Vitro Investigation of the Glutathione Transferase M1 and T1 Null Genotypes as Risk Factors for Troglitazone-Induced Liver Injury
      Toru Usui, Takanori Hashizume, Takashi Katsumata, Tsuyoshi Yokoi and Setsuko Komuro
      Drug Metabolism and Disposition July 2011, 39 (7) 1303-1310; DOI: https://doi.org/10.1124/dmd.111.038661
  3. Koda, Hiroko

    1. You have access
      In Vitro Metabolism of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rat, Monkey, and Human Liver Microsomes and Freshly Isolated Hepatocytes
      Minoru Uchiyama, Hiroko Koda, Thomas Fischer, Juergen Mueller, Naotoshi Yamamura, Minoru Oguchi, Haruo Iwabuchi, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition July 2011, 39 (7) 1311-1319; DOI: https://doi.org/10.1124/dmd.111.038729
  4. Koenderink, Jan B.

    1. You have access
      Cannabinoid Type 1 Receptor Antagonists Modulate Transport Activity of Multidrug Resistance-Associated Proteins MRP1, MRP2, MRP3, and MRP4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Heike Dinter-Heidorn, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition July 2011, 39 (7) 1294-1302; DOI: https://doi.org/10.1124/dmd.110.037812
  5. Komuro, Setsuko

    1. You have access
      In Vitro Investigation of the Glutathione Transferase M1 and T1 Null Genotypes as Risk Factors for Troglitazone-Induced Liver Injury
      Toru Usui, Takanori Hashizume, Takashi Katsumata, Tsuyoshi Yokoi and Setsuko Komuro
      Drug Metabolism and Disposition July 2011, 39 (7) 1303-1310; DOI: https://doi.org/10.1124/dmd.111.038661
  6. Krauwinkel, Walter

    1. You have access
      A Semiphysiological Population Model for Prediction of the Pharmacokinetics of Drugs under Liver and Renal Disease Conditions
      Ashley Strougo, Ashraf Yassen, Walter Krauwinkel, Meindert Danhof and Jan Freijer
      Drug Metabolism and Disposition July 2011, 39 (7) 1278-1287; DOI: https://doi.org/10.1124/dmd.110.037838
  7. Kumaraswamy, Padmapriya

    1. You have access
      Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders
      S. Scott Bowersox, Luke K. Lightning, Satish Rao, Monica Palme, Dave Ellis, Renee Coleman, Adrian M. Davies, Padmapriya Kumaraswamy and Pascal Druzgala
      Drug Metabolism and Disposition July 2011, 39 (7) 1170-1180; DOI: https://doi.org/10.1124/dmd.110.037564

L

  1. Lao, Yanbin

    1. You have access
      Disposition and Drug-Drug Interaction Potential of Veliparib (ABT-888), a Novel and Potent Inhibitor of Poly(ADP-ribose) Polymerase
      Xiaofeng Li, Juergen Delzer, Richard Voorman, Sonia M. de Morais and Yanbin Lao
      Drug Metabolism and Disposition July 2011, 39 (7) 1161-1169; DOI: https://doi.org/10.1124/dmd.110.037820
  2. Laverdière, Isabelle

    1. You have access
      In Vitro Investigation of Human UDP-Glucuronosyltransferase Isoforms Responsible for Tacrolimus Glucuronidation: Predominant Contribution of UGT1A4
      Isabelle Laverdière, Patrick Caron, Mario Harvey, Éric Lévesque and Chantal Guillemette
      Drug Metabolism and Disposition July 2011, 39 (7) 1127-1130; DOI: https://doi.org/10.1124/dmd.111.039040
  3. Leslie, Elaine M.

    1. You have access
      Glutathione Transferase P1 Interacts Strongly with the Inner Leaflet of the Plasma Membrane
      Sohail S. Qazi, Anaida Osoria Pérez, Medica Sam and Elaine M. Leslie
      Drug Metabolism and Disposition July 2011, 39 (7) 1122-1126; DOI: https://doi.org/10.1124/dmd.111.039362
  4. Lévesque, Éric

    1. You have access
      In Vitro Investigation of Human UDP-Glucuronosyltransferase Isoforms Responsible for Tacrolimus Glucuronidation: Predominant Contribution of UGT1A4
      Isabelle Laverdière, Patrick Caron, Mario Harvey, Éric Lévesque and Chantal Guillemette
      Drug Metabolism and Disposition July 2011, 39 (7) 1127-1130; DOI: https://doi.org/10.1124/dmd.111.039040
  5. Li, Jibin

    1. You have access
      Use of Transporter Knockdown Caco-2 Cells to Investigate the In Vitro Efflux of Statin Drugs
      Jibin Li, Donna A. Volpe, Ying Wang, Wei Zhang, Chris Bode, Albert Owen and Ismael J. Hidalgo
      Drug Metabolism and Disposition July 2011, 39 (7) 1196-1202; DOI: https://doi.org/10.1124/dmd.111.038075
  6. Li, Xiaofeng

    1. You have access
      Disposition and Drug-Drug Interaction Potential of Veliparib (ABT-888), a Novel and Potent Inhibitor of Poly(ADP-ribose) Polymerase
      Xiaofeng Li, Juergen Delzer, Richard Voorman, Sonia M. de Morais and Yanbin Lao
      Drug Metabolism and Disposition July 2011, 39 (7) 1161-1169; DOI: https://doi.org/10.1124/dmd.110.037820
  7. Lightning, Luke K.

    1. You have access
      Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders
      S. Scott Bowersox, Luke K. Lightning, Satish Rao, Monica Palme, Dave Ellis, Renee Coleman, Adrian M. Davies, Padmapriya Kumaraswamy and Pascal Druzgala
      Drug Metabolism and Disposition July 2011, 39 (7) 1170-1180; DOI: https://doi.org/10.1124/dmd.110.037564
  8. Lin, Zhen

    1. You have access
      Species Independence in Brain Tissue Binding Using Brain Homogenates
      Li Di, John P. Umland, George Chang, Youping Huang, Zhen Lin, Dennis O. Scott, Matthew D. Troutman and Theodore E. Liston
      Drug Metabolism and Disposition July 2011, 39 (7) 1270-1277; DOI: https://doi.org/10.1124/dmd.111.038778
  9. Liston, Theodore E.

    1. You have access
      Species Independence in Brain Tissue Binding Using Brain Homogenates
      Li Di, John P. Umland, George Chang, Youping Huang, Zhen Lin, Dennis O. Scott, Matthew D. Troutman and Theodore E. Liston
      Drug Metabolism and Disposition July 2011, 39 (7) 1270-1277; DOI: https://doi.org/10.1124/dmd.111.038778
  10. Lowe, Ezra R.

    1. You have access
      Ocular Pharmacokinetics of Mapracorat, a Novel, Selective Glucocorticoid Receptor Agonist, in Rabbits and Monkeys
      Joel W. Proksch, Ezra R. Lowe and Keith W. Ward
      Drug Metabolism and Disposition July 2011, 39 (7) 1181-1187; DOI: https://doi.org/10.1124/dmd.111.039099
  11. Lu, Jeff Zhiqiang

    1. You have access
      Chronic Dosing of Mice with a Transferrin Receptor Monoclonal Antibody-Glial-Derived Neurotrophic Factor Fusion Protein
      Qing-Hui Zhou, Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition July 2011, 39 (7) 1149-1154; DOI: https://doi.org/10.1124/dmd.111.038349
  12. Luís, Paula B. M.

    1. You have access
      Role of Isovaleryl-CoA Dehydrogenase and Short Branched-Chain Acyl-CoA Dehydrogenase in the Metabolism of Valproic Acid: Implications for the Branched-Chain Amino Acid Oxidation Pathway
      Paula B. M. Luís, Jos P. N. Ruiter, Lodewijk IJlst, Isabel Tavares de Almeida, Marinus Duran, Al-Walid Mohsen, Jerry Vockley, Ronald J. A. Wanders and Margarida F. B. Silva
      Drug Metabolism and Disposition July 2011, 39 (7) 1155-1160; DOI: https://doi.org/10.1124/dmd.110.037606

M

  1. Mingoia, Robert T.

    1. You have access
      Comparative Metabolism of 1,2,3,3,3-Pentafluoropropene in Male and Female Mouse, Rat, Dog, and Human Liver Microsomes and Cytosol and Male Rat Hepatocytes via Oxidative Dehalogenation and Glutathione S-Conjugation Pathways
      Xing Han, Bogdan Szostek, Ching-Hui Yang, Steve F. Cheatham, Robert T. Mingoia, Diane L. Nabb, Shawn A. Gannon, Matthew W. Himmelstein and Gary W. Jepson
      Drug Metabolism and Disposition July 2011, 39 (7) 1288-1293; DOI: https://doi.org/10.1124/dmd.111.038299
  2. Mitsui, Tetsuya

    1. You have access
      Quantitative Prediction of Mechanism-Based Inhibition Caused by Mibefradil in Rats
      Nobuo Sekiguchi, Motohiro Kato, Maiko Takada, Hiroo Watanabe, Shotaro Takata, Tetsuya Mitsui, Yoshinori Aso and Masaki Ishigai
      Drug Metabolism and Disposition July 2011, 39 (7) 1255-1262; DOI: https://doi.org/10.1124/dmd.110.037903
  3. Miyaji, Yoshihiro

    1. You have access
      Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites
      Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe, Yoshihiro Miyaji, Wataru Suzuki, Daisuke Sugiyama, Kazuhito Shiosakai, Kokichi Honda, Noriko Okudaira, Takashi Izumi and Osamu Okazaki
      Drug Metabolism and Disposition July 2011, 39 (7) 1247-1254; DOI: https://doi.org/10.1124/dmd.111.039180
  4. Mohsen, Al-Walid

    1. You have access
      Role of Isovaleryl-CoA Dehydrogenase and Short Branched-Chain Acyl-CoA Dehydrogenase in the Metabolism of Valproic Acid: Implications for the Branched-Chain Amino Acid Oxidation Pathway
      Paula B. M. Luís, Jos P. N. Ruiter, Lodewijk IJlst, Isabel Tavares de Almeida, Marinus Duran, Al-Walid Mohsen, Jerry Vockley, Ronald J. A. Wanders and Margarida F. B. Silva
      Drug Metabolism and Disposition July 2011, 39 (7) 1155-1160; DOI: https://doi.org/10.1124/dmd.110.037606
  5. Mueller, Juergen

    1. You have access
      In Vitro Metabolism of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rat, Monkey, and Human Liver Microsomes and Freshly Isolated Hepatocytes
      Minoru Uchiyama, Hiroko Koda, Thomas Fischer, Juergen Mueller, Naotoshi Yamamura, Minoru Oguchi, Haruo Iwabuchi, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition July 2011, 39 (7) 1311-1319; DOI: https://doi.org/10.1124/dmd.111.038729

N

  1. Nabb, Diane L.

    1. You have access
      Comparative Metabolism of 1,2,3,3,3-Pentafluoropropene in Male and Female Mouse, Rat, Dog, and Human Liver Microsomes and Cytosol and Male Rat Hepatocytes via Oxidative Dehalogenation and Glutathione S-Conjugation Pathways
      Xing Han, Bogdan Szostek, Ching-Hui Yang, Steve F. Cheatham, Robert T. Mingoia, Diane L. Nabb, Shawn A. Gannon, Matthew W. Himmelstein and Gary W. Jepson
      Drug Metabolism and Disposition July 2011, 39 (7) 1288-1293; DOI: https://doi.org/10.1124/dmd.111.038299
  2. Nakayama, Shintaro

    1. You have access
      Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites
      Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe, Yoshihiro Miyaji, Wataru Suzuki, Daisuke Sugiyama, Kazuhito Shiosakai, Kokichi Honda, Noriko Okudaira, Takashi Izumi and Osamu Okazaki
      Drug Metabolism and Disposition July 2011, 39 (7) 1247-1254; DOI: https://doi.org/10.1124/dmd.111.039180
  3. Nozawa, Takaaki

    1. You have access
      Prediction of Human Intestinal Absorption of the Prodrug Temocapril by In Situ Single-Pass Perfusion Using Rat Intestine with Modified Hydrolase Activity
      Takaaki Nozawa and Teruko Imai
      Drug Metabolism and Disposition July 2011, 39 (7) 1263-1269; DOI: https://doi.org/10.1124/dmd.110.037937

O

  1. Obach, Rosendo

    1. You have access
      In Vitro Metabolism of Irosustat, a Novel Steroid Sulfatase Inhibitor: Interspecies Comparison, Metabolite Identification, and Metabolic Enzyme Identification
      Verònica Ventura, Josep Solà, Carles Celma, Concepción Peraire and Rosendo Obach
      Drug Metabolism and Disposition July 2011, 39 (7) 1235-1246; DOI: https://doi.org/10.1124/dmd.111.038315
  2. Oguchi, Minoru

    1. You have access
      In Vitro Metabolism of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rat, Monkey, and Human Liver Microsomes and Freshly Isolated Hepatocytes
      Minoru Uchiyama, Hiroko Koda, Thomas Fischer, Juergen Mueller, Naotoshi Yamamura, Minoru Oguchi, Haruo Iwabuchi, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition July 2011, 39 (7) 1311-1319; DOI: https://doi.org/10.1124/dmd.111.038729
  3. Okazaki, Osamu

    1. You have access
      In Vitro Metabolism of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rat, Monkey, and Human Liver Microsomes and Freshly Isolated Hepatocytes
      Minoru Uchiyama, Hiroko Koda, Thomas Fischer, Juergen Mueller, Naotoshi Yamamura, Minoru Oguchi, Haruo Iwabuchi, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition July 2011, 39 (7) 1311-1319; DOI: https://doi.org/10.1124/dmd.111.038729
    2. You have access
      Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites
      Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe, Yoshihiro Miyaji, Wataru Suzuki, Daisuke Sugiyama, Kazuhito Shiosakai, Kokichi Honda, Noriko Okudaira, Takashi Izumi and Osamu Okazaki
      Drug Metabolism and Disposition July 2011, 39 (7) 1247-1254; DOI: https://doi.org/10.1124/dmd.111.039180
  4. Okudaira, Noriko

    1. You have access
      Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites
      Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe, Yoshihiro Miyaji, Wataru Suzuki, Daisuke Sugiyama, Kazuhito Shiosakai, Kokichi Honda, Noriko Okudaira, Takashi Izumi and Osamu Okazaki
      Drug Metabolism and Disposition July 2011, 39 (7) 1247-1254; DOI: https://doi.org/10.1124/dmd.111.039180
  5. Osoria Pérez, Anaida

    1. You have access
      Glutathione Transferase P1 Interacts Strongly with the Inner Leaflet of the Plasma Membrane
      Sohail S. Qazi, Anaida Osoria Pérez, Medica Sam and Elaine M. Leslie
      Drug Metabolism and Disposition July 2011, 39 (7) 1122-1126; DOI: https://doi.org/10.1124/dmd.111.039362
  6. Owen, Albert

    1. You have access
      Use of Transporter Knockdown Caco-2 Cells to Investigate the In Vitro Efflux of Statin Drugs
      Jibin Li, Donna A. Volpe, Ying Wang, Wei Zhang, Chris Bode, Albert Owen and Ismael J. Hidalgo
      Drug Metabolism and Disposition July 2011, 39 (7) 1196-1202; DOI: https://doi.org/10.1124/dmd.111.038075

P

  1. Palme, Monica

    1. You have access
      Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders
      S. Scott Bowersox, Luke K. Lightning, Satish Rao, Monica Palme, Dave Ellis, Renee Coleman, Adrian M. Davies, Padmapriya Kumaraswamy and Pascal Druzgala
      Drug Metabolism and Disposition July 2011, 39 (7) 1170-1180; DOI: https://doi.org/10.1124/dmd.110.037564
  2. Pardridge, William M.

    1. You have access
      Chronic Dosing of Mice with a Transferrin Receptor Monoclonal Antibody-Glial-Derived Neurotrophic Factor Fusion Protein
      Qing-Hui Zhou, Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition July 2011, 39 (7) 1149-1154; DOI: https://doi.org/10.1124/dmd.111.038349
  3. Pearson, Josh T.

    1. You have access
      Mechanism-Based Inactivation of Cytochrome P450 3A4 by Mibefradil through Heme Destruction
      Robert S. Foti, Dan A. Rock, Josh T. Pearson, Jan L. Wahlstrom and Larry C. Wienkers
      Drug Metabolism and Disposition July 2011, 39 (7) 1188-1195; DOI: https://doi.org/10.1124/dmd.111.038505
  4. Peraire, Concepción

    1. You have access
      In Vitro Metabolism of Irosustat, a Novel Steroid Sulfatase Inhibitor: Interspecies Comparison, Metabolite Identification, and Metabolic Enzyme Identification
      Verònica Ventura, Josep Solà, Carles Celma, Concepción Peraire and Rosendo Obach
      Drug Metabolism and Disposition July 2011, 39 (7) 1235-1246; DOI: https://doi.org/10.1124/dmd.111.038315
  5. Proksch, Joel W.

    1. You have access
      Ocular Pharmacokinetics of Mapracorat, a Novel, Selective Glucocorticoid Receptor Agonist, in Rabbits and Monkeys
      Joel W. Proksch, Ezra R. Lowe and Keith W. Ward
      Drug Metabolism and Disposition July 2011, 39 (7) 1181-1187; DOI: https://doi.org/10.1124/dmd.111.039099

Q

  1. Qazi, Sohail S.

    1. You have access
      Glutathione Transferase P1 Interacts Strongly with the Inner Leaflet of the Plasma Membrane
      Sohail S. Qazi, Anaida Osoria Pérez, Medica Sam and Elaine M. Leslie
      Drug Metabolism and Disposition July 2011, 39 (7) 1122-1126; DOI: https://doi.org/10.1124/dmd.111.039362

R

  1. Rao, Satish

    1. You have access
      Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders
      S. Scott Bowersox, Luke K. Lightning, Satish Rao, Monica Palme, Dave Ellis, Renee Coleman, Adrian M. Davies, Padmapriya Kumaraswamy and Pascal Druzgala
      Drug Metabolism and Disposition July 2011, 39 (7) 1170-1180; DOI: https://doi.org/10.1124/dmd.110.037564
  2. Rock, Dan A.

    1. You have access
      Mechanism-Based Inactivation of Cytochrome P450 3A4 by Mibefradil through Heme Destruction
      Robert S. Foti, Dan A. Rock, Josh T. Pearson, Jan L. Wahlstrom and Larry C. Wienkers
      Drug Metabolism and Disposition July 2011, 39 (7) 1188-1195; DOI: https://doi.org/10.1124/dmd.111.038505
  3. Rosebraugh, Matthew

    1. You have access
      Receptor-Based Dosing Optimization of Erythropoietin in Juvenile Sheep after Phlebotomy
      Matthew Rosebraugh, John A. Widness and Peter Veng-Pedersen
      Drug Metabolism and Disposition July 2011, 39 (7) 1214-1220; DOI: https://doi.org/10.1124/dmd.110.036855
  4. Rossberg, Ingrid

    1. You have access
      Cytochrome P450-Dependent Metabolism in HepaRG Cells Cultured in a Dynamic Three-Dimensional Bioreactor
      Malin Darnell, Thomas Schreiter, Katrin Zeilinger, Thomas Urbaniak, Therese Söderdahl, Ingrid Rossberg, Birgitta Dillnér, Anna-Lena Berg, Jörg C. Gerlach and Tommy B. Andersson
      Drug Metabolism and Disposition July 2011, 39 (7) 1131-1138; DOI: https://doi.org/10.1124/dmd.110.037721
  5. Ruiter, Jos P. N.

    1. You have access
      Role of Isovaleryl-CoA Dehydrogenase and Short Branched-Chain Acyl-CoA Dehydrogenase in the Metabolism of Valproic Acid: Implications for the Branched-Chain Amino Acid Oxidation Pathway
      Paula B. M. Luís, Jos P. N. Ruiter, Lodewijk IJlst, Isabel Tavares de Almeida, Marinus Duran, Al-Walid Mohsen, Jerry Vockley, Ronald J. A. Wanders and Margarida F. B. Silva
      Drug Metabolism and Disposition July 2011, 39 (7) 1155-1160; DOI: https://doi.org/10.1124/dmd.110.037606
  6. Russel, Frans G. M.

    1. You have access
      Cannabinoid Type 1 Receptor Antagonists Modulate Transport Activity of Multidrug Resistance-Associated Proteins MRP1, MRP2, MRP3, and MRP4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Heike Dinter-Heidorn, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition July 2011, 39 (7) 1294-1302; DOI: https://doi.org/10.1124/dmd.110.037812

S

  1. Sam, Medica

    1. You have access
      Glutathione Transferase P1 Interacts Strongly with the Inner Leaflet of the Plasma Membrane
      Sohail S. Qazi, Anaida Osoria Pérez, Medica Sam and Elaine M. Leslie
      Drug Metabolism and Disposition July 2011, 39 (7) 1122-1126; DOI: https://doi.org/10.1124/dmd.111.039362
  2. Schreiter, Thomas

    1. You have access
      Cytochrome P450-Dependent Metabolism in HepaRG Cells Cultured in a Dynamic Three-Dimensional Bioreactor
      Malin Darnell, Thomas Schreiter, Katrin Zeilinger, Thomas Urbaniak, Therese Söderdahl, Ingrid Rossberg, Birgitta Dillnér, Anna-Lena Berg, Jörg C. Gerlach and Tommy B. Andersson
      Drug Metabolism and Disposition July 2011, 39 (7) 1131-1138; DOI: https://doi.org/10.1124/dmd.110.037721
  3. Scott, Dennis O.

    1. You have access
      Species Independence in Brain Tissue Binding Using Brain Homogenates
      Li Di, John P. Umland, George Chang, Youping Huang, Zhen Lin, Dennis O. Scott, Matthew D. Troutman and Theodore E. Liston
      Drug Metabolism and Disposition July 2011, 39 (7) 1270-1277; DOI: https://doi.org/10.1124/dmd.111.038778
  4. Sekiguchi, Nobuo

    1. You have access
      Quantitative Prediction of Mechanism-Based Inhibition Caused by Mibefradil in Rats
      Nobuo Sekiguchi, Motohiro Kato, Maiko Takada, Hiroo Watanabe, Shotaro Takata, Tetsuya Mitsui, Yoshinori Aso and Masaki Ishigai
      Drug Metabolism and Disposition July 2011, 39 (7) 1255-1262; DOI: https://doi.org/10.1124/dmd.110.037903
  5. Shen, Hong-Wu

    1. You have access
      Nonlinear Pharmacokinetics of 5-Methoxy-N,N-dimethyltryptamine in Mice
      Hong-Wu Shen, Xi-Ling Jiang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2011, 39 (7) 1227-1234; DOI: https://doi.org/10.1124/dmd.111.039107
  6. Shiosakai, Kazuhito

    1. You have access
      Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites
      Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe, Yoshihiro Miyaji, Wataru Suzuki, Daisuke Sugiyama, Kazuhito Shiosakai, Kokichi Honda, Noriko Okudaira, Takashi Izumi and Osamu Okazaki
      Drug Metabolism and Disposition July 2011, 39 (7) 1247-1254; DOI: https://doi.org/10.1124/dmd.111.039180
  7. Shou, Magang

    1. You have access
      Simulation of Clinical Drug-Drug Interactions from Hepatocyte CYP3A4 Induction Data and Its Potential Utility in Trial Designs
      Yang Xu, Yihong Zhou, Mike Hayashi, Magang Shou and Gary L. Skiles
      Drug Metabolism and Disposition July 2011, 39 (7) 1139-1148; DOI: https://doi.org/10.1124/dmd.111.038067
  8. Silva, Margarida F. B.

    1. You have access
      Role of Isovaleryl-CoA Dehydrogenase and Short Branched-Chain Acyl-CoA Dehydrogenase in the Metabolism of Valproic Acid: Implications for the Branched-Chain Amino Acid Oxidation Pathway
      Paula B. M. Luís, Jos P. N. Ruiter, Lodewijk IJlst, Isabel Tavares de Almeida, Marinus Duran, Al-Walid Mohsen, Jerry Vockley, Ronald J. A. Wanders and Margarida F. B. Silva
      Drug Metabolism and Disposition July 2011, 39 (7) 1155-1160; DOI: https://doi.org/10.1124/dmd.110.037606
  9. Skiles, Gary L.

    1. You have access
      Simulation of Clinical Drug-Drug Interactions from Hepatocyte CYP3A4 Induction Data and Its Potential Utility in Trial Designs
      Yang Xu, Yihong Zhou, Mike Hayashi, Magang Shou and Gary L. Skiles
      Drug Metabolism and Disposition July 2011, 39 (7) 1139-1148; DOI: https://doi.org/10.1124/dmd.111.038067
  10. Söderdahl, Therese

    1. You have access
      Cytochrome P450-Dependent Metabolism in HepaRG Cells Cultured in a Dynamic Three-Dimensional Bioreactor
      Malin Darnell, Thomas Schreiter, Katrin Zeilinger, Thomas Urbaniak, Therese Söderdahl, Ingrid Rossberg, Birgitta Dillnér, Anna-Lena Berg, Jörg C. Gerlach and Tommy B. Andersson
      Drug Metabolism and Disposition July 2011, 39 (7) 1131-1138; DOI: https://doi.org/10.1124/dmd.110.037721
  11. Solà, Josep

    1. You have access
      In Vitro Metabolism of Irosustat, a Novel Steroid Sulfatase Inhibitor: Interspecies Comparison, Metabolite Identification, and Metabolic Enzyme Identification
      Verònica Ventura, Josep Solà, Carles Celma, Concepción Peraire and Rosendo Obach
      Drug Metabolism and Disposition July 2011, 39 (7) 1235-1246; DOI: https://doi.org/10.1124/dmd.111.038315
  12. Strougo, Ashley

    1. You have access
      A Semiphysiological Population Model for Prediction of the Pharmacokinetics of Drugs under Liver and Renal Disease Conditions
      Ashley Strougo, Ashraf Yassen, Walter Krauwinkel, Meindert Danhof and Jan Freijer
      Drug Metabolism and Disposition July 2011, 39 (7) 1278-1287; DOI: https://doi.org/10.1124/dmd.110.037838
  13. Sugiyama, Daisuke

    1. You have access
      Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites
      Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe, Yoshihiro Miyaji, Wataru Suzuki, Daisuke Sugiyama, Kazuhito Shiosakai, Kokichi Honda, Noriko Okudaira, Takashi Izumi and Osamu Okazaki
      Drug Metabolism and Disposition July 2011, 39 (7) 1247-1254; DOI: https://doi.org/10.1124/dmd.111.039180
  14. Suzuki, Wataru

    1. You have access
      Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites
      Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe, Yoshihiro Miyaji, Wataru Suzuki, Daisuke Sugiyama, Kazuhito Shiosakai, Kokichi Honda, Noriko Okudaira, Takashi Izumi and Osamu Okazaki
      Drug Metabolism and Disposition July 2011, 39 (7) 1247-1254; DOI: https://doi.org/10.1124/dmd.111.039180
  15. Szostek, Bogdan

    1. You have access
      Comparative Metabolism of 1,2,3,3,3-Pentafluoropropene in Male and Female Mouse, Rat, Dog, and Human Liver Microsomes and Cytosol and Male Rat Hepatocytes via Oxidative Dehalogenation and Glutathione S-Conjugation Pathways
      Xing Han, Bogdan Szostek, Ching-Hui Yang, Steve F. Cheatham, Robert T. Mingoia, Diane L. Nabb, Shawn A. Gannon, Matthew W. Himmelstein and Gary W. Jepson
      Drug Metabolism and Disposition July 2011, 39 (7) 1288-1293; DOI: https://doi.org/10.1124/dmd.111.038299

T

  1. Takada, Maiko

    1. You have access
      Quantitative Prediction of Mechanism-Based Inhibition Caused by Mibefradil in Rats
      Nobuo Sekiguchi, Motohiro Kato, Maiko Takada, Hiroo Watanabe, Shotaro Takata, Tetsuya Mitsui, Yoshinori Aso and Masaki Ishigai
      Drug Metabolism and Disposition July 2011, 39 (7) 1255-1262; DOI: https://doi.org/10.1124/dmd.110.037903
  2. Takakusa, Hideo

    1. You have access
      Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites
      Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe, Yoshihiro Miyaji, Wataru Suzuki, Daisuke Sugiyama, Kazuhito Shiosakai, Kokichi Honda, Noriko Okudaira, Takashi Izumi and Osamu Okazaki
      Drug Metabolism and Disposition July 2011, 39 (7) 1247-1254; DOI: https://doi.org/10.1124/dmd.111.039180
  3. Takata, Shotaro

    1. You have access
      Quantitative Prediction of Mechanism-Based Inhibition Caused by Mibefradil in Rats
      Nobuo Sekiguchi, Motohiro Kato, Maiko Takada, Hiroo Watanabe, Shotaro Takata, Tetsuya Mitsui, Yoshinori Aso and Masaki Ishigai
      Drug Metabolism and Disposition July 2011, 39 (7) 1255-1262; DOI: https://doi.org/10.1124/dmd.110.037903
  4. Tavares de Almeida, Isabel

    1. You have access
      Role of Isovaleryl-CoA Dehydrogenase and Short Branched-Chain Acyl-CoA Dehydrogenase in the Metabolism of Valproic Acid: Implications for the Branched-Chain Amino Acid Oxidation Pathway
      Paula B. M. Luís, Jos P. N. Ruiter, Lodewijk IJlst, Isabel Tavares de Almeida, Marinus Duran, Al-Walid Mohsen, Jerry Vockley, Ronald J. A. Wanders and Margarida F. B. Silva
      Drug Metabolism and Disposition July 2011, 39 (7) 1155-1160; DOI: https://doi.org/10.1124/dmd.110.037606
  5. Troutman, Matthew D.

    1. You have access
      Species Independence in Brain Tissue Binding Using Brain Homogenates
      Li Di, John P. Umland, George Chang, Youping Huang, Zhen Lin, Dennis O. Scott, Matthew D. Troutman and Theodore E. Liston
      Drug Metabolism and Disposition July 2011, 39 (7) 1270-1277; DOI: https://doi.org/10.1124/dmd.111.038778

U

  1. Uchiyama, Minoru

    1. You have access
      In Vitro Metabolism of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rat, Monkey, and Human Liver Microsomes and Freshly Isolated Hepatocytes
      Minoru Uchiyama, Hiroko Koda, Thomas Fischer, Juergen Mueller, Naotoshi Yamamura, Minoru Oguchi, Haruo Iwabuchi, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition July 2011, 39 (7) 1311-1319; DOI: https://doi.org/10.1124/dmd.111.038729
  2. Umland, John P.

    1. You have access
      Species Independence in Brain Tissue Binding Using Brain Homogenates
      Li Di, John P. Umland, George Chang, Youping Huang, Zhen Lin, Dennis O. Scott, Matthew D. Troutman and Theodore E. Liston
      Drug Metabolism and Disposition July 2011, 39 (7) 1270-1277; DOI: https://doi.org/10.1124/dmd.111.038778
  3. Urbaniak, Thomas

    1. You have access
      Cytochrome P450-Dependent Metabolism in HepaRG Cells Cultured in a Dynamic Three-Dimensional Bioreactor
      Malin Darnell, Thomas Schreiter, Katrin Zeilinger, Thomas Urbaniak, Therese Söderdahl, Ingrid Rossberg, Birgitta Dillnér, Anna-Lena Berg, Jörg C. Gerlach and Tommy B. Andersson
      Drug Metabolism and Disposition July 2011, 39 (7) 1131-1138; DOI: https://doi.org/10.1124/dmd.110.037721
  4. Usui, Toru

    1. You have access
      In Vitro Investigation of the Glutathione Transferase M1 and T1 Null Genotypes as Risk Factors for Troglitazone-Induced Liver Injury
      Toru Usui, Takanori Hashizume, Takashi Katsumata, Tsuyoshi Yokoi and Setsuko Komuro
      Drug Metabolism and Disposition July 2011, 39 (7) 1303-1310; DOI: https://doi.org/10.1124/dmd.111.038661

V

  1. VanAlstine, Melissa A.

    1. You have access
      Effects of Acetylenic Epoxygenase Inhibitors on Recombinant Cytochrome P450s
      Melissa A. VanAlstine and Lindsay B. Hough
      Drug Metabolism and Disposition July 2011, 39 (7) 1221-1226; DOI: https://doi.org/10.1124/dmd.110.037424
  2. van den Broek, Petra H. H.

    1. You have access
      Cannabinoid Type 1 Receptor Antagonists Modulate Transport Activity of Multidrug Resistance-Associated Proteins MRP1, MRP2, MRP3, and MRP4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Heike Dinter-Heidorn, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition July 2011, 39 (7) 1294-1302; DOI: https://doi.org/10.1124/dmd.110.037812
  3. van den Heuvel, Jeroen J. M. W.

    1. You have access
      Cannabinoid Type 1 Receptor Antagonists Modulate Transport Activity of Multidrug Resistance-Associated Proteins MRP1, MRP2, MRP3, and MRP4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Heike Dinter-Heidorn, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition July 2011, 39 (7) 1294-1302; DOI: https://doi.org/10.1124/dmd.110.037812
  4. Veng-Pedersen, Peter

    1. You have access
      Receptor-Based Dosing Optimization of Erythropoietin in Juvenile Sheep after Phlebotomy
      Matthew Rosebraugh, John A. Widness and Peter Veng-Pedersen
      Drug Metabolism and Disposition July 2011, 39 (7) 1214-1220; DOI: https://doi.org/10.1124/dmd.110.036855
  5. Ventura, Verònica

    1. You have access
      In Vitro Metabolism of Irosustat, a Novel Steroid Sulfatase Inhibitor: Interspecies Comparison, Metabolite Identification, and Metabolic Enzyme Identification
      Verònica Ventura, Josep Solà, Carles Celma, Concepción Peraire and Rosendo Obach
      Drug Metabolism and Disposition July 2011, 39 (7) 1235-1246; DOI: https://doi.org/10.1124/dmd.111.038315
  6. Vockley, Jerry

    1. You have access
      Role of Isovaleryl-CoA Dehydrogenase and Short Branched-Chain Acyl-CoA Dehydrogenase in the Metabolism of Valproic Acid: Implications for the Branched-Chain Amino Acid Oxidation Pathway
      Paula B. M. Luís, Jos P. N. Ruiter, Lodewijk IJlst, Isabel Tavares de Almeida, Marinus Duran, Al-Walid Mohsen, Jerry Vockley, Ronald J. A. Wanders and Margarida F. B. Silva
      Drug Metabolism and Disposition July 2011, 39 (7) 1155-1160; DOI: https://doi.org/10.1124/dmd.110.037606
  7. Volpe, Donna A.

    1. You have access
      Use of Transporter Knockdown Caco-2 Cells to Investigate the In Vitro Efflux of Statin Drugs
      Jibin Li, Donna A. Volpe, Ying Wang, Wei Zhang, Chris Bode, Albert Owen and Ismael J. Hidalgo
      Drug Metabolism and Disposition July 2011, 39 (7) 1196-1202; DOI: https://doi.org/10.1124/dmd.111.038075
  8. Voorman, Richard

    1. You have access
      Disposition and Drug-Drug Interaction Potential of Veliparib (ABT-888), a Novel and Potent Inhibitor of Poly(ADP-ribose) Polymerase
      Xiaofeng Li, Juergen Delzer, Richard Voorman, Sonia M. de Morais and Yanbin Lao
      Drug Metabolism and Disposition July 2011, 39 (7) 1161-1169; DOI: https://doi.org/10.1124/dmd.110.037820

W

  1. Wahlstrom, Jan L.

    1. You have access
      Mechanism-Based Inactivation of Cytochrome P450 3A4 by Mibefradil through Heme Destruction
      Robert S. Foti, Dan A. Rock, Josh T. Pearson, Jan L. Wahlstrom and Larry C. Wienkers
      Drug Metabolism and Disposition July 2011, 39 (7) 1188-1195; DOI: https://doi.org/10.1124/dmd.111.038505
  2. Wanders, Ronald J. A.

    1. You have access
      Role of Isovaleryl-CoA Dehydrogenase and Short Branched-Chain Acyl-CoA Dehydrogenase in the Metabolism of Valproic Acid: Implications for the Branched-Chain Amino Acid Oxidation Pathway
      Paula B. M. Luís, Jos P. N. Ruiter, Lodewijk IJlst, Isabel Tavares de Almeida, Marinus Duran, Al-Walid Mohsen, Jerry Vockley, Ronald J. A. Wanders and Margarida F. B. Silva
      Drug Metabolism and Disposition July 2011, 39 (7) 1155-1160; DOI: https://doi.org/10.1124/dmd.110.037606
  3. Wang, Ying

    1. You have access
      Use of Transporter Knockdown Caco-2 Cells to Investigate the In Vitro Efflux of Statin Drugs
      Jibin Li, Donna A. Volpe, Ying Wang, Wei Zhang, Chris Bode, Albert Owen and Ismael J. Hidalgo
      Drug Metabolism and Disposition July 2011, 39 (7) 1196-1202; DOI: https://doi.org/10.1124/dmd.111.038075
  4. Ward, Keith W.

    1. You have access
      Ocular Pharmacokinetics of Mapracorat, a Novel, Selective Glucocorticoid Receptor Agonist, in Rabbits and Monkeys
      Joel W. Proksch, Ezra R. Lowe and Keith W. Ward
      Drug Metabolism and Disposition July 2011, 39 (7) 1181-1187; DOI: https://doi.org/10.1124/dmd.111.039099
  5. Watanabe, Akiko

    1. You have access
      Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites
      Shintaro Nakayama, Hideo Takakusa, Akiko Watanabe, Yoshihiro Miyaji, Wataru Suzuki, Daisuke Sugiyama, Kazuhito Shiosakai, Kokichi Honda, Noriko Okudaira, Takashi Izumi and Osamu Okazaki
      Drug Metabolism and Disposition July 2011, 39 (7) 1247-1254; DOI: https://doi.org/10.1124/dmd.111.039180
  6. Watanabe, Hiroo

    1. You have access
      Quantitative Prediction of Mechanism-Based Inhibition Caused by Mibefradil in Rats
      Nobuo Sekiguchi, Motohiro Kato, Maiko Takada, Hiroo Watanabe, Shotaro Takata, Tetsuya Mitsui, Yoshinori Aso and Masaki Ishigai
      Drug Metabolism and Disposition July 2011, 39 (7) 1255-1262; DOI: https://doi.org/10.1124/dmd.110.037903
  7. Watson, Kenny J.

    1. You have access
      Application of Physiologically Based Pharmacokinetic Modeling to Understanding the Clinical Pharmacokinetics of UK-369,003
      Kenny J. Watson, John Davis and Hannah M. Jones
      Drug Metabolism and Disposition July 2011, 39 (7) 1203-1213; DOI: https://doi.org/10.1124/dmd.111.038224
  8. Widness, John A.

    1. You have access
      Receptor-Based Dosing Optimization of Erythropoietin in Juvenile Sheep after Phlebotomy
      Matthew Rosebraugh, John A. Widness and Peter Veng-Pedersen
      Drug Metabolism and Disposition July 2011, 39 (7) 1214-1220; DOI: https://doi.org/10.1124/dmd.110.036855
  9. Wienkers, Larry C.

    1. You have access
      Mechanism-Based Inactivation of Cytochrome P450 3A4 by Mibefradil through Heme Destruction
      Robert S. Foti, Dan A. Rock, Josh T. Pearson, Jan L. Wahlstrom and Larry C. Wienkers
      Drug Metabolism and Disposition July 2011, 39 (7) 1188-1195; DOI: https://doi.org/10.1124/dmd.111.038505
  10. Wittgen, Hanneke G. M.

    1. You have access
      Cannabinoid Type 1 Receptor Antagonists Modulate Transport Activity of Multidrug Resistance-Associated Proteins MRP1, MRP2, MRP3, and MRP4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Heike Dinter-Heidorn, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition July 2011, 39 (7) 1294-1302; DOI: https://doi.org/10.1124/dmd.110.037812

X

  1. Xu, Yang

    1. You have access
      Simulation of Clinical Drug-Drug Interactions from Hepatocyte CYP3A4 Induction Data and Its Potential Utility in Trial Designs
      Yang Xu, Yihong Zhou, Mike Hayashi, Magang Shou and Gary L. Skiles
      Drug Metabolism and Disposition July 2011, 39 (7) 1139-1148; DOI: https://doi.org/10.1124/dmd.111.038067

Y

  1. Yamamura, Naotoshi

    1. You have access
      In Vitro Metabolism of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rat, Monkey, and Human Liver Microsomes and Freshly Isolated Hepatocytes
      Minoru Uchiyama, Hiroko Koda, Thomas Fischer, Juergen Mueller, Naotoshi Yamamura, Minoru Oguchi, Haruo Iwabuchi, Osamu Okazaki and Takashi Izumi
      Drug Metabolism and Disposition July 2011, 39 (7) 1311-1319; DOI: https://doi.org/10.1124/dmd.111.038729
  2. Yang, Ching-Hui

    1. You have access
      Comparative Metabolism of 1,2,3,3,3-Pentafluoropropene in Male and Female Mouse, Rat, Dog, and Human Liver Microsomes and Cytosol and Male Rat Hepatocytes via Oxidative Dehalogenation and Glutathione S-Conjugation Pathways
      Xing Han, Bogdan Szostek, Ching-Hui Yang, Steve F. Cheatham, Robert T. Mingoia, Diane L. Nabb, Shawn A. Gannon, Matthew W. Himmelstein and Gary W. Jepson
      Drug Metabolism and Disposition July 2011, 39 (7) 1288-1293; DOI: https://doi.org/10.1124/dmd.111.038299
  3. Yassen, Ashraf

    1. You have access
      A Semiphysiological Population Model for Prediction of the Pharmacokinetics of Drugs under Liver and Renal Disease Conditions
      Ashley Strougo, Ashraf Yassen, Walter Krauwinkel, Meindert Danhof and Jan Freijer
      Drug Metabolism and Disposition July 2011, 39 (7) 1278-1287; DOI: https://doi.org/10.1124/dmd.110.037838
  4. Yokoi, Tsuyoshi

    1. You have access
      In Vitro Investigation of the Glutathione Transferase M1 and T1 Null Genotypes as Risk Factors for Troglitazone-Induced Liver Injury
      Toru Usui, Takanori Hashizume, Takashi Katsumata, Tsuyoshi Yokoi and Setsuko Komuro
      Drug Metabolism and Disposition July 2011, 39 (7) 1303-1310; DOI: https://doi.org/10.1124/dmd.111.038661
  5. Yu, Ai-Ming

    1. You have access
      Nonlinear Pharmacokinetics of 5-Methoxy-N,N-dimethyltryptamine in Mice
      Hong-Wu Shen, Xi-Ling Jiang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2011, 39 (7) 1227-1234; DOI: https://doi.org/10.1124/dmd.111.039107

Z

  1. Zeilinger, Katrin

    1. You have access
      Cytochrome P450-Dependent Metabolism in HepaRG Cells Cultured in a Dynamic Three-Dimensional Bioreactor
      Malin Darnell, Thomas Schreiter, Katrin Zeilinger, Thomas Urbaniak, Therese Söderdahl, Ingrid Rossberg, Birgitta Dillnér, Anna-Lena Berg, Jörg C. Gerlach and Tommy B. Andersson
      Drug Metabolism and Disposition July 2011, 39 (7) 1131-1138; DOI: https://doi.org/10.1124/dmd.110.037721
  2. Zhang, Wei

    1. You have access
      Use of Transporter Knockdown Caco-2 Cells to Investigate the In Vitro Efflux of Statin Drugs
      Jibin Li, Donna A. Volpe, Ying Wang, Wei Zhang, Chris Bode, Albert Owen and Ismael J. Hidalgo
      Drug Metabolism and Disposition July 2011, 39 (7) 1196-1202; DOI: https://doi.org/10.1124/dmd.111.038075
  3. Zhou, Qing-Hui

    1. You have access
      Chronic Dosing of Mice with a Transferrin Receptor Monoclonal Antibody-Glial-Derived Neurotrophic Factor Fusion Protein
      Qing-Hui Zhou, Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition July 2011, 39 (7) 1149-1154; DOI: https://doi.org/10.1124/dmd.111.038349
  4. Zhou, Yihong

    1. You have access
      Simulation of Clinical Drug-Drug Interactions from Hepatocyte CYP3A4 Induction Data and Its Potential Utility in Trial Designs
      Yang Xu, Yihong Zhou, Mike Hayashi, Magang Shou and Gary L. Skiles
      Drug Metabolism and Disposition July 2011, 39 (7) 1139-1148; DOI: https://doi.org/10.1124/dmd.111.038067
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Drug Metabolism and Disposition: 39 (7)
Drug Metabolism and Disposition
Vol. 39, Issue 7
1 Jul 2011
  • Table of Contents
  • Table of Contents (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
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