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Drug Metabolism & Disposition

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    • Current Issue
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Index by author

September 01, 2011; Volume 39,Issue 9
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Anzenbacher, Pavel

    1. You have access
      Interaction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free Doxorubicin
      Vlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel Anzenbacher
      Drug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986
  2. Anzenbacherová, Eva

    1. You have access
      Interaction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free Doxorubicin
      Vlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel Anzenbacher
      Drug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986
  3. Ayoub, Samir S.

    1. You have access
      Paracetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404
      Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David Baker
      Drug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638

B

  1. Baker, David

    1. You have access
      Paracetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404
      Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David Baker
      Drug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638
  2. Baldisseri, Donna M.

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
  3. Benson, Heather A. E.

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
  4. Bershas, David

    1. You have access
      Investigations of Hydrazine Cleavage of Eltrombopag in Humans
      Yanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
  5. Bi, Yi-an

    1. You have access
      Culture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human Hepatocytes
      Naoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
  6. Bigler, Jeannette

    1. You have access
      UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables
      Sandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. Lampe
      Drug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
  7. Bikadi, Zsolt

    1. You have access
      pH-Dependent Transport of Pemetrexed by Breast Cancer Resistance Protein
      Li Li, Yuk Yin Sham, Zsolt Bikadi and William F. Elmquist
      Drug Metabolism and Disposition September 2011, 39 (9) 1478-1485; DOI: https://doi.org/10.1124/dmd.111.039370
  8. Birkett, Donald J.

    1. You have access
      Application of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver Microsomes
      James A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354
  9. Block, Wiebke

    1. You have access
      Oral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in Foals
      Jette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner Siegmund
      Drug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
  10. Bolton, Christopher

    1. You have access
      Paracetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404
      Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David Baker
      Drug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638
  11. Bonifácio, Maria J.

    1. You have access
      Hepatic UDP-Glucuronosyltransferase Is Responsible for Eslicarbazepine Glucuronidation
      Ana I. Loureiro, Carlos Fernandes-Lopes, Maria J. Bonifácio, Lyndon C. Wright and Patricio Soares-da-Silva
      Drug Metabolism and Disposition September 2011, 39 (9) 1486-1494; DOI: https://doi.org/10.1124/dmd.111.038620
  12. Bowen, Carolyn

    1. You have access
      Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects
      Yanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170

C

  1. Carr, Brian

    1. You have access
      Monoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic Consequences
      Weirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant Prueksaritanont
      Drug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
  2. Cartus, Alexander T.

    1. You have access
      Metabolism of Methylisoeugenol in Liver Microsomes of Human, Rat, and Bovine Origin
      Alexander T. Cartus, Karl-Heinz Merz and Dieter Schrenk
      Drug Metabolism and Disposition September 2011, 39 (9) 1727-1733; DOI: https://doi.org/10.1124/dmd.111.038851
  3. Chang, Jyh-Lurn

    1. You have access
      UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables
      Sandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. Lampe
      Drug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
  4. Chang, S.

    1. You have access
      1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-Acetyltransferase
      Q. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. Marathe
      Drug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
  5. Chen, Emile P.

    1. You have access
      Investigations of Hydrazine Cleavage of Eltrombopag in Humans
      Yanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
  6. Chen, Jianjun

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
  7. Chen, Yu

    1. You have access
      UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables
      Sandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. Lampe
      Drug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
  8. Chen, Yuping

    1. You have access
      A Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3A
      Yuping Chen, Gary L. Skiles, Magang Shou, Dean Hickman and Faye Hsieh
      Drug Metabolism and Disposition September 2011, 39 (9) 1668-1673; DOI: https://doi.org/10.1124/dmd.111.039750
  9. Cheng, Yaofeng

    1. You have access
      Characterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In Vivo
      Yaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn Sipes
      Drug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
  10. Christopher, Lisa J.

    1. You have access
      In Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor Inhibitor
      Haizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
  11. Chupka, Jonathan

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
  12. Commandeur, Jan N. M.

    1. You have access
      Efficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical Space
      Jelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
  13. Crozier, Alan

    1. You have access
      Colonic Catabolism of Ellagitannins, Ellagic Acid, and Raspberry Anthocyanins: In Vivo and In Vitro Studies
      Rocío González-Barrio, Christine A. Edwards and Alan Crozier
      Drug Metabolism and Disposition September 2011, 39 (9) 1680-1688; DOI: https://doi.org/10.1124/dmd.111.039651

D

  1. Decker, Caroline J.

    1. You have access
      Efficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical Space
      Jelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
  2. Deng, Yanli

    1. You have access
      Investigations of Hydrazine Cleavage of Eltrombopag in Humans
      Yanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
    2. You have access
      Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects
      Yanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
    3. You have access
      Metabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent Binding
      Catherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
  3. Dierks, E. A.

    1. You have access
      1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-Acetyltransferase
      Q. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. Marathe
      Drug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834

E

  1. Edwards, Christine A.

    1. You have access
      Colonic Catabolism of Ellagitannins, Ellagic Acid, and Raspberry Anthocyanins: In Vivo and In Vitro Studies
      Rocío González-Barrio, Christine A. Edwards and Alan Crozier
      Drug Metabolism and Disposition September 2011, 39 (9) 1680-1688; DOI: https://doi.org/10.1124/dmd.111.039651
  2. Elliot, David J.

    1. You have access
      Application of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver Microsomes
      James A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354
  3. Elmquist, William F.

    1. You have access
      pH-Dependent Transport of Pemetrexed by Breast Cancer Resistance Protein
      Li Li, Yuk Yin Sham, Zsolt Bikadi and William F. Elmquist
      Drug Metabolism and Disposition September 2011, 39 (9) 1478-1485; DOI: https://doi.org/10.1124/dmd.111.039370
  4. Endo, Yuya

    1. You have access
      Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene
      Keigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki Kume
      Drug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
  5. Etrych, Tomáš

    1. You have access
      Interaction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free Doxorubicin
      Vlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel Anzenbacher
      Drug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986

F

  1. Fæste, Christiane K.

    1. You have access
      In Vitro Metabolism of the Mycotoxin Enniatin B in Different Species and Cytochrome P450 Enzyme Phenotyping by Chemical Inhibitors
      Christiane K. Fæste, Lada Ivanova and Silvio Uhlig
      Drug Metabolism and Disposition September 2011, 39 (9) 1768-1776; DOI: https://doi.org/10.1124/dmd.111.039529
  2. Fang, Yulin

    1. You have access
      Monoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic Consequences
      Weirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant Prueksaritanont
      Drug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
  3. Feng, Bo

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
  4. Fernandes-Lopes, Carlos

    1. You have access
      Hepatic UDP-Glucuronosyltransferase Is Responsible for Eslicarbazepine Glucuronidation
      Ana I. Loureiro, Carlos Fernandes-Lopes, Maria J. Bonifácio, Lyndon C. Wright and Patricio Soares-da-Silva
      Drug Metabolism and Disposition September 2011, 39 (9) 1486-1494; DOI: https://doi.org/10.1124/dmd.111.038620
  5. Flower, Roderick J.

    1. You have access
      Paracetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404
      Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David Baker
      Drug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638
  6. Foti, Robert S.

    1. You have access
      Evaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe Substrate
      Brooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. Wahlstrom
      Drug Metabolism and Disposition September 2011, 39 (9) 1546-1554; DOI: https://doi.org/10.1124/dmd.111.039065
  7. Freyer, Johanna

    1. You have access
      Oral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in Foals
      Jette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner Siegmund
      Drug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
  8. Frye, Reginald F.

    1. You have access
      Inhibitory Effects of Commonly Used Herbal Extracts on UDP-Glucuronosyltransferase 1A4, 1A6, and 1A9 Enzyme Activities
      Mohamed-Eslam F. Mohamed and Reginald F. Frye
      Drug Metabolism and Disposition September 2011, 39 (9) 1522-1528; DOI: https://doi.org/10.1124/dmd.111.039602
  9. Fukuhara, Yuga

    1. You have access
      Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene
      Keigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki Kume
      Drug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
  10. Fukuuchi, Tomoko

    1. You have access
      Novel Pathway of Metabolic Activation of Bisphenol A-Related Compounds for Estrogenic Activity
      Katsuhiro Okuda, Tomoko Fukuuchi, Masufumi Takiguchi and Shin'ichi Yoshihara
      Drug Metabolism and Disposition September 2011, 39 (9) 1696-1703; DOI: https://doi.org/10.1124/dmd.111.040121
  11. Furuta, Takashi

    1. You have access
      Metabolism and Disposition of Isoflavone Conjugated Metabolites in Humans after Ingestion of Kinako
      Kaori Hosoda, Takashi Furuta and Kazuo Ishii
      Drug Metabolism and Disposition September 2011, 39 (9) 1762-1767; DOI: https://doi.org/10.1124/dmd.111.038281

G

  1. Galetin, Aleksandra

    1. You have access
      Physiologically Based Pharmacokinetic Modeling of Intestinal First-Pass Metabolism of CYP3A Substrates with High Intestinal Extraction
      Michael Gertz, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition September 2011, 39 (9) 1633-1642; DOI: https://doi.org/10.1124/dmd.111.039248
  2. Gentry, W. Brooks

    1. You have access
      Gestation Time-Dependent Pharmacokinetics of Intravenous (+)-Methamphetamine in Rats
      Sarah White, Elizabeth Laurenzana, Howard Hendrickson, W. Brooks Gentry and S. Michael Owens
      Drug Metabolism and Disposition September 2011, 39 (9) 1718-1726; DOI: https://doi.org/10.1124/dmd.111.039446
  3. Gerk, Phillip M.

    1. You have access
      Preclinical Disposition (In Vitro) of Novel μ-Opioid Receptor Selective Antagonists
      Pallabi Mitra, Jürgen Venitz, Yunyun Yuan, Yan Zhang and Phillip M. Gerk
      Drug Metabolism and Disposition September 2011, 39 (9) 1589-1596; DOI: https://doi.org/10.1124/dmd.111.038588
  4. Gertz, Michael

    1. You have access
      Physiologically Based Pharmacokinetic Modeling of Intestinal First-Pass Metabolism of CYP3A Substrates with High Intestinal Extraction
      Michael Gertz, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition September 2011, 39 (9) 1633-1642; DOI: https://doi.org/10.1124/dmd.111.039248
  5. Gong, Li-kun

    1. You have access
      Culture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human Hepatocytes
      Naoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
  6. González-Barrio, Rocío

    1. You have access
      Colonic Catabolism of Ellagitannins, Ellagic Acid, and Raspberry Anthocyanins: In Vivo and In Vitro Studies
      Rocío González-Barrio, Christine A. Edwards and Alan Crozier
      Drug Metabolism and Disposition September 2011, 39 (9) 1680-1688; DOI: https://doi.org/10.1124/dmd.111.039651
  7. Gorycki, Frances

    1. You have access
      Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects
      Yanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
  8. Gorycki, Peter D.

    1. You have access
      Investigations of Hydrazine Cleavage of Eltrombopag in Humans
      Yanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
    2. You have access
      Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects
      Yanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
    3. You have access
      Metabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent Binding
      Catherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
  9. Grimm, Scott W.

    1. You have access
      Disposition and Metabolism of Ticagrelor, a Novel P2Y12 Receptor Antagonist, in Mice, Rats, and Marmosets
      Yan Li, Claire Landqvist and Scott W. Grimm
      Drug Metabolism and Disposition September 2011, 39 (9) 1555-1567; DOI: https://doi.org/10.1124/dmd.111.039669
  10. Grootenhuis, Peter D. J.

    1. You have access
      Efficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical Space
      Jelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
  11. Grube, Markus

    1. You have access
      Oral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in Foals
      Jette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner Siegmund
      Drug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
  12. Guo, Dean

    1. You have access
      From Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in Rats
      Cheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min Ye
      Drug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695

H

  1. Hamuro, Lora

    1. You have access
      Monoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic Consequences
      Weirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant Prueksaritanont
      Drug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
  2. Hardesty, William M.

    1. You have access
      Metabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent Binding
      Catherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
  3. Harper, T. W.

    1. You have access
      1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-Acetyltransferase
      Q. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. Marathe
      Drug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
  4. Hendrickson, Howard

    1. You have access
      Gestation Time-Dependent Pharmacokinetics of Intravenous (+)-Methamphetamine in Rats
      Sarah White, Elizabeth Laurenzana, Howard Hendrickson, W. Brooks Gentry and S. Michael Owens
      Drug Metabolism and Disposition September 2011, 39 (9) 1718-1726; DOI: https://doi.org/10.1124/dmd.111.039446
  5. Hickman, Dean

    1. You have access
      A Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3A
      Yuping Chen, Gary L. Skiles, Magang Shou, Dean Hickman and Faye Hsieh
      Drug Metabolism and Disposition September 2011, 39 (9) 1668-1673; DOI: https://doi.org/10.1124/dmd.111.039750
  6. Hiramatsu, Mariko

    1. You have access
      Culture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human Hepatocytes
      Naoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
  7. Ho, May

    1. You have access
      Investigations of Hydrazine Cleavage of Eltrombopag in Humans
      Yanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
  8. Hochman, Jerome

    1. You have access
      Monoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic Consequences
      Weirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant Prueksaritanont
      Drug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
  9. Hong, Haizheng

    1. You have access
      In Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor Inhibitor
      Haizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
  10. Hooth, Michelle J.

    1. You have access
      Characterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In Vivo
      Yaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn Sipes
      Drug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
  11. Hosoda, Kaori

    1. You have access
      Metabolism and Disposition of Isoflavone Conjugated Metabolites in Humans after Ingestion of Kinako
      Kaori Hosoda, Takashi Furuta and Kazuo Ishii
      Drug Metabolism and Disposition September 2011, 39 (9) 1762-1767; DOI: https://doi.org/10.1124/dmd.111.038281
  12. Houston, J. Brian

    1. You have access
      Physiologically Based Pharmacokinetic Modeling of Intestinal First-Pass Metabolism of CYP3A Substrates with High Intestinal Extraction
      Michael Gertz, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition September 2011, 39 (9) 1633-1642; DOI: https://doi.org/10.1124/dmd.111.039248
  13. Howell, Danielle E.

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
  14. Hsieh, Faye

    1. You have access
      A Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3A
      Yuping Chen, Gary L. Skiles, Magang Shou, Dean Hickman and Faye Hsieh
      Drug Metabolism and Disposition September 2011, 39 (9) 1668-1673; DOI: https://doi.org/10.1124/dmd.111.039750
  15. Humphreys, W. Griffith

    1. You have access
      In Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor Inhibitor
      Haizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776

I

  1. Ikushiro, Shinichi

    1. You have access
      Sequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875
  2. Ishii, Kazuo

    1. You have access
      Metabolism and Disposition of Isoflavone Conjugated Metabolites in Humans after Ingestion of Kinako
      Kaori Hosoda, Takashi Furuta and Kazuo Ishii
      Drug Metabolism and Disposition September 2011, 39 (9) 1762-1767; DOI: https://doi.org/10.1124/dmd.111.038281
  3. Ivanova, Lada

    1. You have access
      In Vitro Metabolism of the Mycotoxin Enniatin B in Different Species and Cytochrome P450 Enzyme Phenotyping by Chemical Inhibitors
      Christiane K. Fæste, Lada Ivanova and Silvio Uhlig
      Drug Metabolism and Disposition September 2011, 39 (9) 1768-1776; DOI: https://doi.org/10.1124/dmd.111.039529
  4. Iyer, Ramaswamy A.

    1. You have access
      In Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor Inhibitor
      Haizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776

J

  1. Jadhav, Gajanan

    1. You have access
      Ocular Pharmacokinetics of Dorzolamide and Brinzolamide After Single and Multiple Topical Dosing: Implications for Effects on Ocular Blood Flow
      Rajendra S. Kadam, Gajanan Jadhav, Miller Ogidigben and Uday B. Kompella
      Drug Metabolism and Disposition September 2011, 39 (9) 1529-1537; DOI: https://doi.org/10.1124/dmd.111.040055
  2. Janjetovic, Zorica

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071

K

  1. Kadam, Rajendra S.

    1. You have access
      Ocular Pharmacokinetics of Dorzolamide and Brinzolamide After Single and Multiple Topical Dosing: Implications for Effects on Ocular Blood Flow
      Rajendra S. Kadam, Gajanan Jadhav, Miller Ogidigben and Uday B. Kompella
      Drug Metabolism and Disposition September 2011, 39 (9) 1529-1537; DOI: https://doi.org/10.1124/dmd.111.040055
  2. Kalgutkar, Amit S.

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
  3. Kamakura, Masaki

    1. You have access
      Sequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875
  4. Kim, Tae-Kang

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
  5. Kimoto, Emi

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
  6. King, Irena B.

    1. You have access
      UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables
      Sandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. Lampe
      Drug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
  7. Kino, Ichiro

    1. You have access
      Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene
      Keigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki Kume
      Drug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
  8. Kompella, Uday B.

    1. You have access
      Ocular Pharmacokinetics of Dorzolamide and Brinzolamide After Single and Multiple Topical Dosing: Implications for Effects on Ocular Blood Flow
      Rajendra S. Kadam, Gajanan Jadhav, Miller Ogidigben and Uday B. Kompella
      Drug Metabolism and Disposition September 2011, 39 (9) 1529-1537; DOI: https://doi.org/10.1124/dmd.111.040055
  9. Kosaka, Keigo

    1. You have access
      Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene
      Keigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki Kume
      Drug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
  10. Kotani, Naoki

    1. You have access
      Culture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human Hepatocytes
      Naoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
  11. Kroemer, Heyo K.

    1. You have access
      Oral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in Foals
      Jette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner Siegmund
      Drug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
  12. Kuester, Robert K.

    1. You have access
      Characterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In Vivo
      Yaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn Sipes
      Drug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
  13. Kume, Toshiyuki

    1. You have access
      Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene
      Keigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki Kume
      Drug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
  14. Kusuhara, Hiroyuki

    1. You have access
      Culture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human Hepatocytes
      Naoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968

L

  1. Lämmer, Marc

    1. You have access
      Oral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in Foals
      Jette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner Siegmund
      Drug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
  2. Lampe, Johanna W.

    1. You have access
      UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables
      Sandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. Lampe
      Drug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
  3. Landqvist, Claire

    1. You have access
      Disposition and Metabolism of Ticagrelor, a Novel P2Y12 Receptor Antagonist, in Mice, Rats, and Marmosets
      Yan Li, Claire Landqvist and Scott W. Grimm
      Drug Metabolism and Disposition September 2011, 39 (9) 1555-1567; DOI: https://doi.org/10.1124/dmd.111.039669
  4. Laurenzana, Elizabeth

    1. You have access
      Gestation Time-Dependent Pharmacokinetics of Intravenous (+)-Methamphetamine in Rats
      Sarah White, Elizabeth Laurenzana, Howard Hendrickson, W. Brooks Gentry and S. Michael Owens
      Drug Metabolism and Disposition September 2011, 39 (9) 1718-1726; DOI: https://doi.org/10.1124/dmd.111.039446
  5. Levy, Mark

    1. You have access
      Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects
      Yanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
  6. Li, Li

    1. You have access
      pH-Dependent Transport of Pemetrexed by Breast Cancer Resistance Protein
      Li Li, Yuk Yin Sham, Zsolt Bikadi and William F. Elmquist
      Drug Metabolism and Disposition September 2011, 39 (9) 1478-1485; DOI: https://doi.org/10.1124/dmd.111.039370
  7. Li, Lin

    1. You have access
      UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables
      Sandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. Lampe
      Drug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
  8. Li, Rui

    1. You have access
      From Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in Rats
      Cheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min Ye
      Drug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695
  9. Li, Shuying S.

    1. You have access
      UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables
      Sandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. Lampe
      Drug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
  10. Li, Wei

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
  11. Li, Yan

    1. You have access
      Disposition and Metabolism of Ticagrelor, a Novel P2Y12 Receptor Antagonist, in Mice, Rats, and Marmosets
      Yan Li, Claire Landqvist and Scott W. Grimm
      Drug Metabolism and Disposition September 2011, 39 (9) 1555-1567; DOI: https://doi.org/10.1124/dmd.111.039669
  12. Li, Yongmin

    1. You have access
      Efficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical Space
      Jelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
  13. Loureiro, Ana I.

    1. You have access
      Hepatic UDP-Glucuronosyltransferase Is Responsible for Eslicarbazepine Glucuronidation
      Ana I. Loureiro, Carlos Fernandes-Lopes, Maria J. Bonifácio, Lyndon C. Wright and Patricio Soares-da-Silva
      Drug Metabolism and Disposition September 2011, 39 (9) 1486-1494; DOI: https://doi.org/10.1124/dmd.111.038620
  14. Lu, Ping

    1. You have access
      Monoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic Consequences
      Weirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant Prueksaritanont
      Drug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
  15. Lütjohann, Dieter

    1. You have access
      Oral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in Foals
      Jette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner Siegmund
      Drug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206

M

  1. Ma, Li

    1. You have access
      In Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor Inhibitor
      Haizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
  2. Madatian, Armina

    1. You have access
      Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects
      Yanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
    2. You have access
      Metabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent Binding
      Catherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
  3. Maeda, Kazuya

    1. You have access
      Culture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human Hepatocytes
      Naoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
  4. Marathe, P.

    1. You have access
      1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-Acetyltransferase
      Q. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. Marathe
      Drug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
  5. Martinez-Guerrero, Lucy J.

    1. You have access
      Characterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In Vivo
      Yaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn Sipes
      Drug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
  6. Mascitti, Vincent

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
  7. Mašek, Vlastimil

    1. You have access
      Interaction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free Doxorubicin
      Vlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel Anzenbacher
      Drug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986
  8. McLure, James A.

    1. You have access
      Application of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver Microsomes
      James A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354
  9. Merz, Karl-Heinz

    1. You have access
      Metabolism of Methylisoeugenol in Liver Microsomes of Human, Rat, and Bovine Origin
      Alexander T. Cartus, Karl-Heinz Merz and Dieter Schrenk
      Drug Metabolism and Disposition September 2011, 39 (9) 1727-1733; DOI: https://doi.org/10.1124/dmd.111.038851
  10. Miao, Wenjuan

    1. You have access
      From Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in Rats
      Cheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min Ye
      Drug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695
  11. Miao, Zhuang

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
  12. Miners, John O.

    1. You have access
      Application of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver Microsomes
      James A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354
  13. Mitra, Pallabi

    1. You have access
      Preclinical Disposition (In Vitro) of Novel μ-Opioid Receptor Selective Antagonists
      Pallabi Mitra, Jürgen Venitz, Yunyun Yuan, Yan Zhang and Phillip M. Gerk
      Drug Metabolism and Disposition September 2011, 39 (9) 1589-1596; DOI: https://doi.org/10.1124/dmd.111.038588
  14. Mohamed, Mohamed-Eslam F.

    1. You have access
      Inhibitory Effects of Commonly Used Herbal Extracts on UDP-Glucuronosyltransferase 1A4, 1A6, and 1A9 Enzyme Activities
      Mohamed-Eslam F. Mohamed and Reginald F. Frye
      Drug Metabolism and Disposition September 2011, 39 (9) 1522-1528; DOI: https://doi.org/10.1124/dmd.111.039602
  15. Moore, David J.

    1. You have access
      Bioactivation of Glafenine by Human Liver Microsomes and Peroxidases: Identification of Electrophilic Iminoquinone Species and GSH Conjugates
      Bo Wen and David J. Moore
      Drug Metabolism and Disposition September 2011, 39 (9) 1511-1521; DOI: https://doi.org/10.1124/dmd.111.039396
  16. Munetsuna, Eiji

    1. You have access
      Sequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875

N

  1. Navarro, Sandi L.

    1. You have access
      UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables
      Sandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. Lampe
      Drug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
  2. Nguyen, Minh N.

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071

O

  1. Ogidigben, Miller

    1. You have access
      Ocular Pharmacokinetics of Dorzolamide and Brinzolamide After Single and Multiple Topical Dosing: Implications for Effects on Ocular Blood Flow
      Rajendra S. Kadam, Gajanan Jadhav, Miller Ogidigben and Uday B. Kompella
      Drug Metabolism and Disposition September 2011, 39 (9) 1529-1537; DOI: https://doi.org/10.1124/dmd.111.040055
  2. Ohta, Miho

    1. You have access
      Sequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875
  3. Ohtsuka, Tatsuyuki

    1. You have access
      Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene
      Keigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki Kume
      Drug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
  4. Okuda, Katsuhiro

    1. You have access
      Novel Pathway of Metabolic Activation of Bisphenol A-Related Compounds for Estrogenic Activity
      Katsuhiro Okuda, Tomoko Fukuuchi, Masufumi Takiguchi and Shin'ichi Yoshihara
      Drug Metabolism and Disposition September 2011, 39 (9) 1696-1703; DOI: https://doi.org/10.1124/dmd.111.040121
  5. Oswald, Stefan

    1. You have access
      Oral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in Foals
      Jette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner Siegmund
      Drug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
  6. Owens, S. Michael

    1. You have access
      Gestation Time-Dependent Pharmacokinetics of Intravenous (+)-Methamphetamine in Rats
      Sarah White, Elizabeth Laurenzana, Howard Hendrickson, W. Brooks Gentry and S. Michael Owens
      Drug Metabolism and Disposition September 2011, 39 (9) 1718-1726; DOI: https://doi.org/10.1124/dmd.111.039446

P

  1. Park, Jung Wook

    1. You have access
      Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects
      Yanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
  2. Peng, Bin

    1. You have access
      Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects
      Yanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
  3. Peters, Jette

    1. You have access
      Oral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in Foals
      Jette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner Siegmund
      Drug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
  4. Pittman, Tamara

    1. You have access
      Monoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic Consequences
      Weirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant Prueksaritanont
      Drug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
  5. Potter, John D.

    1. You have access
      UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables
      Sandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. Lampe
      Drug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
  6. Prueksaritanont, Thomayant

    1. You have access
      Monoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic Consequences
      Weirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant Prueksaritanont
      Drug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
  7. Pryce, Gareth

    1. You have access
      Paracetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404
      Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David Baker
      Drug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638

Q

  1. Qian, Yanwen

    1. You have access
      Investigations of Hydrazine Cleavage of Eltrombopag in Humans
      Yanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
  2. Qiao, Xue

    1. You have access
      From Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in Rats
      Cheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min Ye
      Drug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695

R

  1. Reinen, Jelle

    1. You have access
      Efficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical Space
      Jelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
  2. Robinson, Ralph P.

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
  3. Rock, Dan A.

    1. You have access
      Evaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe Substrate
      Brooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. Wahlstrom
      Drug Metabolism and Disposition September 2011, 39 (9) 1546-1554; DOI: https://doi.org/10.1124/dmd.111.039065
  4. Rodrigues, A. D.

    1. You have access
      1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-Acetyltransferase
      Q. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. Marathe
      Drug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
  5. Rogers, Martin

    1. You have access
      Investigations of Hydrazine Cleavage of Eltrombopag in Humans
      Yanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
  6. Rowland, Andrew

    1. You have access
      Application of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver Microsomes
      James A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354

S

  1. Sakai, Norifumi

    1. You have access
      Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene
      Keigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki Kume
      Drug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
  2. Sakaki, Toshiyuki

    1. You have access
      Sequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875
  3. Saunders, John

    1. You have access
      Efficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical Space
      Jelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
  4. Schrenk, Dieter

    1. You have access
      Metabolism of Methylisoeugenol in Liver Microsomes of Human, Rat, and Bovine Origin
      Alexander T. Cartus, Karl-Heinz Merz and Dieter Schrenk
      Drug Metabolism and Disposition September 2011, 39 (9) 1727-1733; DOI: https://doi.org/10.1124/dmd.111.038851
  5. Schubert, Ernest

    1. You have access
      Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects
      Yanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
  6. Schubert, Ernest M.

    1. You have access
      Metabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent Binding
      Catherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
  7. Schwarz, Yvonne

    1. You have access
      UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables
      Sandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. Lampe
      Drug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
  8. Seed, Michael P.

    1. You have access
      Paracetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404
      Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David Baker
      Drug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638
  9. Serabjit-Singh, Cosette

    1. You have access
      Investigations of Hydrazine Cleavage of Eltrombopag in Humans
      Yanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
  10. Seymour, Jennifer L.

    1. You have access
      Metabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent Binding
      Catherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
  11. Sham, Yuk Yin

    1. You have access
      pH-Dependent Transport of Pemetrexed by Breast Cancer Resistance Protein
      Li Li, Yuk Yin Sham, Zsolt Bikadi and William F. Elmquist
      Drug Metabolism and Disposition September 2011, 39 (9) 1478-1485; DOI: https://doi.org/10.1124/dmd.111.039370
  12. Shehabi, Haleem Z.

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
  13. Shi, Wei

    1. You have access
      Investigations of Hydrazine Cleavage of Eltrombopag in Humans
      Yanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
  14. Shou, Magang

    1. You have access
      A Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3A
      Yuping Chen, Gary L. Skiles, Magang Shou, Dean Hickman and Faye Hsieh
      Drug Metabolism and Disposition September 2011, 39 (9) 1668-1673; DOI: https://doi.org/10.1124/dmd.111.039750
  15. Siegmund, Werner

    1. You have access
      Oral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in Foals
      Jette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner Siegmund
      Drug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
  16. Sipes, I. Glenn

    1. You have access
      Characterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In Vivo
      Yaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn Sipes
      Drug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
  17. Skiles, Gary L.

    1. You have access
      A Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3A
      Yuping Chen, Gary L. Skiles, Magang Shou, Dean Hickman and Faye Hsieh
      Drug Metabolism and Disposition September 2011, 39 (9) 1668-1673; DOI: https://doi.org/10.1124/dmd.111.039750
  18. Slominski, Andrzej

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
  19. Soares-da-Silva, Patricio

    1. You have access
      Hepatic UDP-Glucuronosyltransferase Is Responsible for Eslicarbazepine Glucuronidation
      Ana I. Loureiro, Carlos Fernandes-Lopes, Maria J. Bonifácio, Lyndon C. Wright and Patricio Soares-da-Silva
      Drug Metabolism and Disposition September 2011, 39 (9) 1486-1494; DOI: https://doi.org/10.1124/dmd.111.038620
  20. Strohalm, Jiří

    1. You have access
      Interaction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free Doxorubicin
      Vlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel Anzenbacher
      Drug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986
  21. Su, Hong

    1. You have access
      In Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor Inhibitor
      Haizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
  22. Sugiyama, Yuichi

    1. You have access
      Culture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human Hepatocytes
      Naoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
  23. Sun, Lifang

    1. You have access
      Efficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical Space
      Jelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
  24. Sun, Q.

    1. You have access
      1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-Acetyltransferase
      Q. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. Marathe
      Drug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
  25. Sweatman, Trevor

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
  26. Sychterz, Caroline

    1. You have access
      Investigations of Hydrazine Cleavage of Eltrombopag in Humans
      Yanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188

T

  1. Takahashi, Masakatsu

    1. You have access
      Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene
      Keigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki Kume
      Drug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
  2. Takeba, Naomi

    1. You have access
      Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene
      Keigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki Kume
      Drug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
  3. Takezawa, Toshiaki

    1. You have access
      Culture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human Hepatocytes
      Naoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
  4. Takiguchi, Masufumi

    1. You have access
      Novel Pathway of Metabolic Activation of Bisphenol A-Related Compounds for Estrogenic Activity
      Katsuhiro Okuda, Tomoko Fukuuchi, Masufumi Takiguchi and Shin'ichi Yoshihara
      Drug Metabolism and Disposition September 2011, 39 (9) 1696-1703; DOI: https://doi.org/10.1124/dmd.111.040121
  5. Talley, Kimberly

    1. You have access
      Investigations of Hydrazine Cleavage of Eltrombopag in Humans
      Yanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
  6. Tan, Beijing

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
  7. Tanimoto, Tomohiko

    1. You have access
      Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene
      Keigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki Kume
      Drug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
  8. Tsalta, Catherine D.

    1. You have access
      Metabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent Binding
      Catherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
  9. Tsuda-Tsukimoto, Minoru

    1. You have access
      Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene
      Keigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki Kume
      Drug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
  10. Tuckey, Robert C.

    1. You have access
      Production of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin Cells
      Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej Slominski
      Drug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
  11. Tugnait, Meera

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675

U

  1. Uhlig, Silvio

    1. You have access
      In Vitro Metabolism of the Mycotoxin Enniatin B in Different Species and Cytochrome P450 Enzyme Phenotyping by Chemical Inhibitors
      Christiane K. Fæste, Lada Ivanova and Silvio Uhlig
      Drug Metabolism and Disposition September 2011, 39 (9) 1768-1776; DOI: https://doi.org/10.1124/dmd.111.039529
  2. Ulbrich, Karel

    1. You have access
      Interaction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free Doxorubicin
      Vlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel Anzenbacher
      Drug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986

V

  1. VandenBrink, Brooke M.

    1. You have access
      Evaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe Substrate
      Brooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. Wahlstrom
      Drug Metabolism and Disposition September 2011, 39 (9) 1546-1554; DOI: https://doi.org/10.1124/dmd.111.039065
  2. van Leeuwen, Jolanda S.

    1. You have access
      Efficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical Space
      Jelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
  3. Venitz, Jürgen

    1. You have access
      Preclinical Disposition (In Vitro) of Novel μ-Opioid Receptor Selective Antagonists
      Pallabi Mitra, Jürgen Venitz, Yunyun Yuan, Yan Zhang and Phillip M. Gerk
      Drug Metabolism and Disposition September 2011, 39 (9) 1589-1596; DOI: https://doi.org/10.1124/dmd.111.038588
  4. Venner, Monica

    1. You have access
      Oral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in Foals
      Jette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner Siegmund
      Drug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
  5. Vermeulen, Nico P. E.

    1. You have access
      Efficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical Space
      Jelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. Commandeur
      Drug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461

W

  1. Wahlstrom, Jan L.

    1. You have access
      Evaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe Substrate
      Brooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. Wahlstrom
      Drug Metabolism and Disposition September 2011, 39 (9) 1546-1554; DOI: https://doi.org/10.1124/dmd.111.039065
  2. Walsky, Robert L.

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
  3. Wang, Qing

    1. You have access
      From Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in Rats
      Cheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min Ye
      Drug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695
  4. Wang, Weirong

    1. You have access
      Monoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic Consequences
      Weirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant Prueksaritanont
      Drug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
  5. Watanabe, Takao

    1. You have access
      Culture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human Hepatocytes
      Naoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
  6. Wen, Bo

    1. You have access
      Bioactivation of Glafenine by Human Liver Microsomes and Peroxidases: Identification of Electrophilic Iminoquinone Species and GSH Conjugates
      Bo Wen and David J. Moore
      Drug Metabolism and Disposition September 2011, 39 (9) 1511-1521; DOI: https://doi.org/10.1124/dmd.111.039396
  7. White, Sarah

    1. You have access
      Gestation Time-Dependent Pharmacokinetics of Intravenous (+)-Methamphetamine in Rats
      Sarah White, Elizabeth Laurenzana, Howard Hendrickson, W. Brooks Gentry and S. Michael Owens
      Drug Metabolism and Disposition September 2011, 39 (9) 1718-1726; DOI: https://doi.org/10.1124/dmd.111.039446
  8. Wienkers, Larry C.

    1. You have access
      Evaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe Substrate
      Brooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. Wahlstrom
      Drug Metabolism and Disposition September 2011, 39 (9) 1546-1554; DOI: https://doi.org/10.1124/dmd.111.039065
  9. Williams, Daphne

    1. You have access
      Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects
      Yanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
  10. Williams, J. Andrew

    1. You have access
      Application of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver Microsomes
      James A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354
  11. Wire, Mary Beth

    1. You have access
      Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human Subjects
      Yanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
  12. Wright, Lyndon C.

    1. You have access
      Hepatic UDP-Glucuronosyltransferase Is Responsible for Eslicarbazepine Glucuronidation
      Ana I. Loureiro, Carlos Fernandes-Lopes, Maria J. Bonifácio, Lyndon C. Wright and Patricio Soares-da-Silva
      Drug Metabolism and Disposition September 2011, 39 (9) 1486-1494; DOI: https://doi.org/10.1124/dmd.111.038620
  13. Wright, Stephen H.

    1. You have access
      Characterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In Vivo
      Yaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn Sipes
      Drug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865

X

  1. Xia, Fangming

    1. You have access
      Metabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent Binding
      Catherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. Gorycki
      Drug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
  2. Xiang, Cheng

    1. You have access
      From Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in Rats
      Cheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min Ye
      Drug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695

Y

  1. Yang, Xin

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
  2. Yao, Ming

    1. You have access
      In Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor Inhibitor
      Haizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
  3. Yasuda, Kaori

    1. You have access
      Sequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875
  4. Ye, Min

    1. You have access
      From Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in Rats
      Cheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min Ye
      Drug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695
  5. Yoshihara, Shin'ichi

    1. You have access
      Novel Pathway of Metabolic Activation of Bisphenol A-Related Compounds for Estrogenic Activity
      Katsuhiro Okuda, Tomoko Fukuuchi, Masufumi Takiguchi and Shin'ichi Yoshihara
      Drug Metabolism and Disposition September 2011, 39 (9) 1696-1703; DOI: https://doi.org/10.1124/dmd.111.040121
  6. Yuan, Yunyun

    1. You have access
      Preclinical Disposition (In Vitro) of Novel μ-Opioid Receptor Selective Antagonists
      Pallabi Mitra, Jürgen Venitz, Yunyun Yuan, Yan Zhang and Phillip M. Gerk
      Drug Metabolism and Disposition September 2011, 39 (9) 1589-1596; DOI: https://doi.org/10.1124/dmd.111.038588

Z

  1. Zhang, L.

    1. You have access
      1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-Acetyltransferase
      Q. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. Marathe
      Drug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
  2. Zhang, Yan

    1. You have access
      Preclinical Disposition (In Vitro) of Novel μ-Opioid Receptor Selective Antagonists
      Pallabi Mitra, Jürgen Venitz, Yunyun Yuan, Yan Zhang and Phillip M. Gerk
      Drug Metabolism and Disposition September 2011, 39 (9) 1589-1596; DOI: https://doi.org/10.1124/dmd.111.038588
  3. Zhu, Tong

    1. You have access
      Preclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes Mellitus
      Amit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. Robinson
      Drug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
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Drug Metabolism and Disposition: 39 (9)
Drug Metabolism and Disposition
Vol. 39, Issue 9
1 Sep 2011
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ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

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