Index by author
September 01, 2011; Volume 39,Issue 9
A
Anzenbacher, Pavel
- You have accessInteraction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free DoxorubicinVlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel AnzenbacherDrug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986
Anzenbacherová, Eva
- You have accessInteraction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free DoxorubicinVlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel AnzenbacherDrug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986
Ayoub, Samir S.
- You have accessParacetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David BakerDrug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638
B
Baker, David
- You have accessParacetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David BakerDrug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638
Baldisseri, Donna M.
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
Benson, Heather A. E.
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
Bershas, David
- You have accessInvestigations of Hydrazine Cleavage of Eltrombopag in HumansYanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
Bi, Yi-an
- You have accessCulture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human HepatocytesNaoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
Bigler, Jeannette
- You have accessUGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and VegetablesSandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. LampeDrug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
Bikadi, Zsolt
- You have accesspH-Dependent Transport of Pemetrexed by Breast Cancer Resistance ProteinLi Li, Yuk Yin Sham, Zsolt Bikadi and William F. ElmquistDrug Metabolism and Disposition September 2011, 39 (9) 1478-1485; DOI: https://doi.org/10.1124/dmd.111.039370
Birkett, Donald J.
- You have accessApplication of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver MicrosomesJames A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. MinersDrug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354
Block, Wiebke
- You have accessOral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in FoalsJette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner SiegmundDrug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
Bolton, Christopher
- You have accessParacetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David BakerDrug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638
Bonifácio, Maria J.
- You have accessHepatic UDP-Glucuronosyltransferase Is Responsible for Eslicarbazepine GlucuronidationAna I. Loureiro, Carlos Fernandes-Lopes, Maria J. Bonifácio, Lyndon C. Wright and Patricio Soares-da-SilvaDrug Metabolism and Disposition September 2011, 39 (9) 1486-1494; DOI: https://doi.org/10.1124/dmd.111.038620
Bowen, Carolyn
- You have accessMetabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
C
Carr, Brian
- You have accessMonoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic ConsequencesWeirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant PrueksaritanontDrug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
Cartus, Alexander T.
- You have accessMetabolism of Methylisoeugenol in Liver Microsomes of Human, Rat, and Bovine OriginAlexander T. Cartus, Karl-Heinz Merz and Dieter SchrenkDrug Metabolism and Disposition September 2011, 39 (9) 1727-1733; DOI: https://doi.org/10.1124/dmd.111.038851
Chang, Jyh-Lurn
- You have accessUGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and VegetablesSandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. LampeDrug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
Chang, S.
- You have access1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-AcetyltransferaseQ. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. MaratheDrug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
Chen, Emile P.
- You have accessInvestigations of Hydrazine Cleavage of Eltrombopag in HumansYanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
Chen, Jianjun
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
Chen, Yu
- You have accessUGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and VegetablesSandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. LampeDrug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
Chen, Yuping
- You have accessA Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3AYuping Chen, Gary L. Skiles, Magang Shou, Dean Hickman and Faye HsiehDrug Metabolism and Disposition September 2011, 39 (9) 1668-1673; DOI: https://doi.org/10.1124/dmd.111.039750
Cheng, Yaofeng
- You have accessCharacterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In VivoYaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn SipesDrug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
Christopher, Lisa J.
- You have accessIn Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor InhibitorHaizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
Chupka, Jonathan
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
Commandeur, Jan N. M.
- You have accessEfficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical SpaceJelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. CommandeurDrug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
Crozier, Alan
- You have accessColonic Catabolism of Ellagitannins, Ellagic Acid, and Raspberry Anthocyanins: In Vivo and In Vitro StudiesRocío González-Barrio, Christine A. Edwards and Alan CrozierDrug Metabolism and Disposition September 2011, 39 (9) 1680-1688; DOI: https://doi.org/10.1124/dmd.111.039651
D
Decker, Caroline J.
- You have accessEfficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical SpaceJelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. CommandeurDrug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
Deng, Yanli
- You have accessInvestigations of Hydrazine Cleavage of Eltrombopag in HumansYanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
- You have accessMetabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
- You have accessMetabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent BindingCatherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
Dierks, E. A.
- You have access1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-AcetyltransferaseQ. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. MaratheDrug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
E
Edwards, Christine A.
- You have accessColonic Catabolism of Ellagitannins, Ellagic Acid, and Raspberry Anthocyanins: In Vivo and In Vitro StudiesRocío González-Barrio, Christine A. Edwards and Alan CrozierDrug Metabolism and Disposition September 2011, 39 (9) 1680-1688; DOI: https://doi.org/10.1124/dmd.111.039651
Elliot, David J.
- You have accessApplication of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver MicrosomesJames A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. MinersDrug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354
Elmquist, William F.
- You have accesspH-Dependent Transport of Pemetrexed by Breast Cancer Resistance ProteinLi Li, Yuk Yin Sham, Zsolt Bikadi and William F. ElmquistDrug Metabolism and Disposition September 2011, 39 (9) 1478-1485; DOI: https://doi.org/10.1124/dmd.111.039370
Endo, Yuya
- You have accessImpact of Intestinal Glucuronidation on the Pharmacokinetics of RaloxifeneKeigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki KumeDrug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
Etrych, Tomáš
- You have accessInteraction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free DoxorubicinVlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel AnzenbacherDrug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986
F
Fæste, Christiane K.
- You have accessIn Vitro Metabolism of the Mycotoxin Enniatin B in Different Species and Cytochrome P450 Enzyme Phenotyping by Chemical InhibitorsChristiane K. Fæste, Lada Ivanova and Silvio UhligDrug Metabolism and Disposition September 2011, 39 (9) 1768-1776; DOI: https://doi.org/10.1124/dmd.111.039529
Fang, Yulin
- You have accessMonoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic ConsequencesWeirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant PrueksaritanontDrug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
Feng, Bo
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
Fernandes-Lopes, Carlos
- You have accessHepatic UDP-Glucuronosyltransferase Is Responsible for Eslicarbazepine GlucuronidationAna I. Loureiro, Carlos Fernandes-Lopes, Maria J. Bonifácio, Lyndon C. Wright and Patricio Soares-da-SilvaDrug Metabolism and Disposition September 2011, 39 (9) 1486-1494; DOI: https://doi.org/10.1124/dmd.111.038620
Flower, Roderick J.
- You have accessParacetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David BakerDrug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638
Foti, Robert S.
- You have accessEvaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe SubstrateBrooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. WahlstromDrug Metabolism and Disposition September 2011, 39 (9) 1546-1554; DOI: https://doi.org/10.1124/dmd.111.039065
Freyer, Johanna
- You have accessOral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in FoalsJette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner SiegmundDrug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
Frye, Reginald F.
- You have accessInhibitory Effects of Commonly Used Herbal Extracts on UDP-Glucuronosyltransferase 1A4, 1A6, and 1A9 Enzyme ActivitiesMohamed-Eslam F. Mohamed and Reginald F. FryeDrug Metabolism and Disposition September 2011, 39 (9) 1522-1528; DOI: https://doi.org/10.1124/dmd.111.039602
Fukuhara, Yuga
- You have accessImpact of Intestinal Glucuronidation on the Pharmacokinetics of RaloxifeneKeigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki KumeDrug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
Fukuuchi, Tomoko
- You have accessNovel Pathway of Metabolic Activation of Bisphenol A-Related Compounds for Estrogenic ActivityKatsuhiro Okuda, Tomoko Fukuuchi, Masufumi Takiguchi and Shin'ichi YoshiharaDrug Metabolism and Disposition September 2011, 39 (9) 1696-1703; DOI: https://doi.org/10.1124/dmd.111.040121
Furuta, Takashi
- You have accessMetabolism and Disposition of Isoflavone Conjugated Metabolites in Humans after Ingestion of KinakoKaori Hosoda, Takashi Furuta and Kazuo IshiiDrug Metabolism and Disposition September 2011, 39 (9) 1762-1767; DOI: https://doi.org/10.1124/dmd.111.038281
G
Galetin, Aleksandra
- You have accessPhysiologically Based Pharmacokinetic Modeling of Intestinal First-Pass Metabolism of CYP3A Substrates with High Intestinal ExtractionMichael Gertz, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2011, 39 (9) 1633-1642; DOI: https://doi.org/10.1124/dmd.111.039248
Gentry, W. Brooks
- You have accessGestation Time-Dependent Pharmacokinetics of Intravenous (+)-Methamphetamine in RatsSarah White, Elizabeth Laurenzana, Howard Hendrickson, W. Brooks Gentry and S. Michael OwensDrug Metabolism and Disposition September 2011, 39 (9) 1718-1726; DOI: https://doi.org/10.1124/dmd.111.039446
Gerk, Phillip M.
- You have accessPreclinical Disposition (In Vitro) of Novel μ-Opioid Receptor Selective AntagonistsPallabi Mitra, Jürgen Venitz, Yunyun Yuan, Yan Zhang and Phillip M. GerkDrug Metabolism and Disposition September 2011, 39 (9) 1589-1596; DOI: https://doi.org/10.1124/dmd.111.038588
Gertz, Michael
- You have accessPhysiologically Based Pharmacokinetic Modeling of Intestinal First-Pass Metabolism of CYP3A Substrates with High Intestinal ExtractionMichael Gertz, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2011, 39 (9) 1633-1642; DOI: https://doi.org/10.1124/dmd.111.039248
Gong, Li-kun
- You have accessCulture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human HepatocytesNaoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
González-Barrio, Rocío
- You have accessColonic Catabolism of Ellagitannins, Ellagic Acid, and Raspberry Anthocyanins: In Vivo and In Vitro StudiesRocío González-Barrio, Christine A. Edwards and Alan CrozierDrug Metabolism and Disposition September 2011, 39 (9) 1680-1688; DOI: https://doi.org/10.1124/dmd.111.039651
Gorycki, Frances
- You have accessMetabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
Gorycki, Peter D.
- You have accessInvestigations of Hydrazine Cleavage of Eltrombopag in HumansYanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
- You have accessMetabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
- You have accessMetabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent BindingCatherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
Grimm, Scott W.
- You have accessDisposition and Metabolism of Ticagrelor, a Novel P2Y12 Receptor Antagonist, in Mice, Rats, and MarmosetsYan Li, Claire Landqvist and Scott W. GrimmDrug Metabolism and Disposition September 2011, 39 (9) 1555-1567; DOI: https://doi.org/10.1124/dmd.111.039669
Grootenhuis, Peter D. J.
- You have accessEfficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical SpaceJelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. CommandeurDrug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
Grube, Markus
- You have accessOral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in FoalsJette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner SiegmundDrug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
Guo, Dean
- You have accessFrom Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in RatsCheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min YeDrug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695
H
Hamuro, Lora
- You have accessMonoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic ConsequencesWeirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant PrueksaritanontDrug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
Hardesty, William M.
- You have accessMetabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent BindingCatherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
Harper, T. W.
- You have access1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-AcetyltransferaseQ. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. MaratheDrug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
Hendrickson, Howard
- You have accessGestation Time-Dependent Pharmacokinetics of Intravenous (+)-Methamphetamine in RatsSarah White, Elizabeth Laurenzana, Howard Hendrickson, W. Brooks Gentry and S. Michael OwensDrug Metabolism and Disposition September 2011, 39 (9) 1718-1726; DOI: https://doi.org/10.1124/dmd.111.039446
Hickman, Dean
- You have accessA Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3AYuping Chen, Gary L. Skiles, Magang Shou, Dean Hickman and Faye HsiehDrug Metabolism and Disposition September 2011, 39 (9) 1668-1673; DOI: https://doi.org/10.1124/dmd.111.039750
Hiramatsu, Mariko
- You have accessCulture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human HepatocytesNaoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
Ho, May
- You have accessInvestigations of Hydrazine Cleavage of Eltrombopag in HumansYanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
Hochman, Jerome
- You have accessMonoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic ConsequencesWeirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant PrueksaritanontDrug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
Hong, Haizheng
- You have accessIn Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor InhibitorHaizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
Hooth, Michelle J.
- You have accessCharacterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In VivoYaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn SipesDrug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
Hosoda, Kaori
- You have accessMetabolism and Disposition of Isoflavone Conjugated Metabolites in Humans after Ingestion of KinakoKaori Hosoda, Takashi Furuta and Kazuo IshiiDrug Metabolism and Disposition September 2011, 39 (9) 1762-1767; DOI: https://doi.org/10.1124/dmd.111.038281
Houston, J. Brian
- You have accessPhysiologically Based Pharmacokinetic Modeling of Intestinal First-Pass Metabolism of CYP3A Substrates with High Intestinal ExtractionMichael Gertz, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2011, 39 (9) 1633-1642; DOI: https://doi.org/10.1124/dmd.111.039248
Howell, Danielle E.
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
Hsieh, Faye
- You have accessA Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3AYuping Chen, Gary L. Skiles, Magang Shou, Dean Hickman and Faye HsiehDrug Metabolism and Disposition September 2011, 39 (9) 1668-1673; DOI: https://doi.org/10.1124/dmd.111.039750
Humphreys, W. Griffith
- You have accessIn Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor InhibitorHaizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
I
Ikushiro, Shinichi
- You have accessSequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human LiverKaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875
Ishii, Kazuo
- You have accessMetabolism and Disposition of Isoflavone Conjugated Metabolites in Humans after Ingestion of KinakoKaori Hosoda, Takashi Furuta and Kazuo IshiiDrug Metabolism and Disposition September 2011, 39 (9) 1762-1767; DOI: https://doi.org/10.1124/dmd.111.038281
Ivanova, Lada
- You have accessIn Vitro Metabolism of the Mycotoxin Enniatin B in Different Species and Cytochrome P450 Enzyme Phenotyping by Chemical InhibitorsChristiane K. Fæste, Lada Ivanova and Silvio UhligDrug Metabolism and Disposition September 2011, 39 (9) 1768-1776; DOI: https://doi.org/10.1124/dmd.111.039529
Iyer, Ramaswamy A.
- You have accessIn Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor InhibitorHaizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
J
Jadhav, Gajanan
- You have accessOcular Pharmacokinetics of Dorzolamide and Brinzolamide After Single and Multiple Topical Dosing: Implications for Effects on Ocular Blood FlowRajendra S. Kadam, Gajanan Jadhav, Miller Ogidigben and Uday B. KompellaDrug Metabolism and Disposition September 2011, 39 (9) 1529-1537; DOI: https://doi.org/10.1124/dmd.111.040055
Janjetovic, Zorica
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
K
Kadam, Rajendra S.
- You have accessOcular Pharmacokinetics of Dorzolamide and Brinzolamide After Single and Multiple Topical Dosing: Implications for Effects on Ocular Blood FlowRajendra S. Kadam, Gajanan Jadhav, Miller Ogidigben and Uday B. KompellaDrug Metabolism and Disposition September 2011, 39 (9) 1529-1537; DOI: https://doi.org/10.1124/dmd.111.040055
Kalgutkar, Amit S.
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
Kamakura, Masaki
- You have accessSequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human LiverKaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875
Kim, Tae-Kang
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
Kimoto, Emi
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
King, Irena B.
- You have accessUGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and VegetablesSandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. LampeDrug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
Kino, Ichiro
- You have accessImpact of Intestinal Glucuronidation on the Pharmacokinetics of RaloxifeneKeigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki KumeDrug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
Kompella, Uday B.
- You have accessOcular Pharmacokinetics of Dorzolamide and Brinzolamide After Single and Multiple Topical Dosing: Implications for Effects on Ocular Blood FlowRajendra S. Kadam, Gajanan Jadhav, Miller Ogidigben and Uday B. KompellaDrug Metabolism and Disposition September 2011, 39 (9) 1529-1537; DOI: https://doi.org/10.1124/dmd.111.040055
Kosaka, Keigo
- You have accessImpact of Intestinal Glucuronidation on the Pharmacokinetics of RaloxifeneKeigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki KumeDrug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
Kotani, Naoki
- You have accessCulture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human HepatocytesNaoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
Kroemer, Heyo K.
- You have accessOral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in FoalsJette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner SiegmundDrug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
Kuester, Robert K.
- You have accessCharacterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In VivoYaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn SipesDrug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
Kume, Toshiyuki
- You have accessImpact of Intestinal Glucuronidation on the Pharmacokinetics of RaloxifeneKeigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki KumeDrug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
Kusuhara, Hiroyuki
- You have accessCulture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human HepatocytesNaoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
L
Lämmer, Marc
- You have accessOral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in FoalsJette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner SiegmundDrug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
Lampe, Johanna W.
- You have accessUGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and VegetablesSandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. LampeDrug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
Landqvist, Claire
- You have accessDisposition and Metabolism of Ticagrelor, a Novel P2Y12 Receptor Antagonist, in Mice, Rats, and MarmosetsYan Li, Claire Landqvist and Scott W. GrimmDrug Metabolism and Disposition September 2011, 39 (9) 1555-1567; DOI: https://doi.org/10.1124/dmd.111.039669
Laurenzana, Elizabeth
- You have accessGestation Time-Dependent Pharmacokinetics of Intravenous (+)-Methamphetamine in RatsSarah White, Elizabeth Laurenzana, Howard Hendrickson, W. Brooks Gentry and S. Michael OwensDrug Metabolism and Disposition September 2011, 39 (9) 1718-1726; DOI: https://doi.org/10.1124/dmd.111.039446
Levy, Mark
- You have accessMetabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
Li, Li
- You have accesspH-Dependent Transport of Pemetrexed by Breast Cancer Resistance ProteinLi Li, Yuk Yin Sham, Zsolt Bikadi and William F. ElmquistDrug Metabolism and Disposition September 2011, 39 (9) 1478-1485; DOI: https://doi.org/10.1124/dmd.111.039370
Li, Lin
- You have accessUGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and VegetablesSandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. LampeDrug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
Li, Rui
- You have accessFrom Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in RatsCheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min YeDrug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695
Li, Shuying S.
- You have accessUGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and VegetablesSandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. LampeDrug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
Li, Wei
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
Li, Yan
- You have accessDisposition and Metabolism of Ticagrelor, a Novel P2Y12 Receptor Antagonist, in Mice, Rats, and MarmosetsYan Li, Claire Landqvist and Scott W. GrimmDrug Metabolism and Disposition September 2011, 39 (9) 1555-1567; DOI: https://doi.org/10.1124/dmd.111.039669
Li, Yongmin
- You have accessEfficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical SpaceJelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. CommandeurDrug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
Loureiro, Ana I.
- You have accessHepatic UDP-Glucuronosyltransferase Is Responsible for Eslicarbazepine GlucuronidationAna I. Loureiro, Carlos Fernandes-Lopes, Maria J. Bonifácio, Lyndon C. Wright and Patricio Soares-da-SilvaDrug Metabolism and Disposition September 2011, 39 (9) 1486-1494; DOI: https://doi.org/10.1124/dmd.111.038620
Lu, Ping
- You have accessMonoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic ConsequencesWeirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant PrueksaritanontDrug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
Lütjohann, Dieter
- You have accessOral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in FoalsJette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner SiegmundDrug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
M
Ma, Li
- You have accessIn Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor InhibitorHaizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
Madatian, Armina
- You have accessMetabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
- You have accessMetabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent BindingCatherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
Maeda, Kazuya
- You have accessCulture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human HepatocytesNaoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
Marathe, P.
- You have access1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-AcetyltransferaseQ. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. MaratheDrug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
Martinez-Guerrero, Lucy J.
- You have accessCharacterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In VivoYaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn SipesDrug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
Mascitti, Vincent
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
Mašek, Vlastimil
- You have accessInteraction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free DoxorubicinVlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel AnzenbacherDrug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986
McLure, James A.
- You have accessApplication of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver MicrosomesJames A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. MinersDrug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354
Merz, Karl-Heinz
- You have accessMetabolism of Methylisoeugenol in Liver Microsomes of Human, Rat, and Bovine OriginAlexander T. Cartus, Karl-Heinz Merz and Dieter SchrenkDrug Metabolism and Disposition September 2011, 39 (9) 1727-1733; DOI: https://doi.org/10.1124/dmd.111.038851
Miao, Wenjuan
- You have accessFrom Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in RatsCheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min YeDrug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695
Miao, Zhuang
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
Miners, John O.
- You have accessApplication of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver MicrosomesJames A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. MinersDrug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354
Mitra, Pallabi
- You have accessPreclinical Disposition (In Vitro) of Novel μ-Opioid Receptor Selective AntagonistsPallabi Mitra, Jürgen Venitz, Yunyun Yuan, Yan Zhang and Phillip M. GerkDrug Metabolism and Disposition September 2011, 39 (9) 1589-1596; DOI: https://doi.org/10.1124/dmd.111.038588
Mohamed, Mohamed-Eslam F.
- You have accessInhibitory Effects of Commonly Used Herbal Extracts on UDP-Glucuronosyltransferase 1A4, 1A6, and 1A9 Enzyme ActivitiesMohamed-Eslam F. Mohamed and Reginald F. FryeDrug Metabolism and Disposition September 2011, 39 (9) 1522-1528; DOI: https://doi.org/10.1124/dmd.111.039602
Moore, David J.
- You have accessBioactivation of Glafenine by Human Liver Microsomes and Peroxidases: Identification of Electrophilic Iminoquinone Species and GSH ConjugatesBo Wen and David J. MooreDrug Metabolism and Disposition September 2011, 39 (9) 1511-1521; DOI: https://doi.org/10.1124/dmd.111.039396
Munetsuna, Eiji
- You have accessSequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human LiverKaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875
N
Navarro, Sandi L.
- You have accessUGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and VegetablesSandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. LampeDrug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
Nguyen, Minh N.
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
O
Ogidigben, Miller
- You have accessOcular Pharmacokinetics of Dorzolamide and Brinzolamide After Single and Multiple Topical Dosing: Implications for Effects on Ocular Blood FlowRajendra S. Kadam, Gajanan Jadhav, Miller Ogidigben and Uday B. KompellaDrug Metabolism and Disposition September 2011, 39 (9) 1529-1537; DOI: https://doi.org/10.1124/dmd.111.040055
Ohta, Miho
- You have accessSequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human LiverKaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875
Ohtsuka, Tatsuyuki
- You have accessImpact of Intestinal Glucuronidation on the Pharmacokinetics of RaloxifeneKeigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki KumeDrug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
Okuda, Katsuhiro
- You have accessNovel Pathway of Metabolic Activation of Bisphenol A-Related Compounds for Estrogenic ActivityKatsuhiro Okuda, Tomoko Fukuuchi, Masufumi Takiguchi and Shin'ichi YoshiharaDrug Metabolism and Disposition September 2011, 39 (9) 1696-1703; DOI: https://doi.org/10.1124/dmd.111.040121
Oswald, Stefan
- You have accessOral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in FoalsJette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner SiegmundDrug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
Owens, S. Michael
- You have accessGestation Time-Dependent Pharmacokinetics of Intravenous (+)-Methamphetamine in RatsSarah White, Elizabeth Laurenzana, Howard Hendrickson, W. Brooks Gentry and S. Michael OwensDrug Metabolism and Disposition September 2011, 39 (9) 1718-1726; DOI: https://doi.org/10.1124/dmd.111.039446
P
Park, Jung Wook
- You have accessMetabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
Peng, Bin
- You have accessMetabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
Peters, Jette
- You have accessOral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in FoalsJette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner SiegmundDrug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
Pittman, Tamara
- You have accessMonoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic ConsequencesWeirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant PrueksaritanontDrug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
Potter, John D.
- You have accessUGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and VegetablesSandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. LampeDrug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
Prueksaritanont, Thomayant
- You have accessMonoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic ConsequencesWeirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant PrueksaritanontDrug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
Pryce, Gareth
- You have accessParacetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David BakerDrug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638
Q
Qian, Yanwen
- You have accessInvestigations of Hydrazine Cleavage of Eltrombopag in HumansYanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
Qiao, Xue
- You have accessFrom Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in RatsCheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min YeDrug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695
R
Reinen, Jelle
- You have accessEfficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical SpaceJelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. CommandeurDrug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
Robinson, Ralph P.
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
Rock, Dan A.
- You have accessEvaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe SubstrateBrooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. WahlstromDrug Metabolism and Disposition September 2011, 39 (9) 1546-1554; DOI: https://doi.org/10.1124/dmd.111.039065
Rodrigues, A. D.
- You have access1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-AcetyltransferaseQ. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. MaratheDrug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
Rogers, Martin
- You have accessInvestigations of Hydrazine Cleavage of Eltrombopag in HumansYanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
Rowland, Andrew
- You have accessApplication of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver MicrosomesJames A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. MinersDrug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354
S
Sakai, Norifumi
- You have accessImpact of Intestinal Glucuronidation on the Pharmacokinetics of RaloxifeneKeigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki KumeDrug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
Sakaki, Toshiyuki
- You have accessSequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human LiverKaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875
Saunders, John
- You have accessEfficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical SpaceJelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. CommandeurDrug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
Schrenk, Dieter
- You have accessMetabolism of Methylisoeugenol in Liver Microsomes of Human, Rat, and Bovine OriginAlexander T. Cartus, Karl-Heinz Merz and Dieter SchrenkDrug Metabolism and Disposition September 2011, 39 (9) 1727-1733; DOI: https://doi.org/10.1124/dmd.111.038851
Schubert, Ernest
- You have accessMetabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
Schubert, Ernest M.
- You have accessMetabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent BindingCatherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
Schwarz, Yvonne
- You have accessUGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and VegetablesSandi L. Navarro, Yu Chen, Lin Li, Shuying S. Li, Jyh-Lurn Chang, Yvonne Schwarz, Irena B. King, John D. Potter, Jeannette Bigler and Johanna W. LampeDrug Metabolism and Disposition September 2011, 39 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.111.039149
Seed, Michael P.
- You have accessParacetamol-Induced Hypothermia Is Independent of Cannabinoids and Transient Receptor Potential Vanilloid-1 and Is Not Mediated by AM404Samir S. Ayoub, Gareth Pryce, Michael P. Seed, Christopher Bolton, Roderick J. Flower and David BakerDrug Metabolism and Disposition September 2011, 39 (9) 1689-1695; DOI: https://doi.org/10.1124/dmd.111.038638
Serabjit-Singh, Cosette
- You have accessInvestigations of Hydrazine Cleavage of Eltrombopag in HumansYanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
Seymour, Jennifer L.
- You have accessMetabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent BindingCatherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
Sham, Yuk Yin
- You have accesspH-Dependent Transport of Pemetrexed by Breast Cancer Resistance ProteinLi Li, Yuk Yin Sham, Zsolt Bikadi and William F. ElmquistDrug Metabolism and Disposition September 2011, 39 (9) 1478-1485; DOI: https://doi.org/10.1124/dmd.111.039370
Shehabi, Haleem Z.
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
Shi, Wei
- You have accessInvestigations of Hydrazine Cleavage of Eltrombopag in HumansYanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
Shou, Magang
- You have accessA Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3AYuping Chen, Gary L. Skiles, Magang Shou, Dean Hickman and Faye HsiehDrug Metabolism and Disposition September 2011, 39 (9) 1668-1673; DOI: https://doi.org/10.1124/dmd.111.039750
Siegmund, Werner
- You have accessOral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in FoalsJette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner SiegmundDrug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
Sipes, I. Glenn
- You have accessCharacterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In VivoYaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn SipesDrug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
Skiles, Gary L.
- You have accessA Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3AYuping Chen, Gary L. Skiles, Magang Shou, Dean Hickman and Faye HsiehDrug Metabolism and Disposition September 2011, 39 (9) 1668-1673; DOI: https://doi.org/10.1124/dmd.111.039750
Slominski, Andrzej
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
Soares-da-Silva, Patricio
- You have accessHepatic UDP-Glucuronosyltransferase Is Responsible for Eslicarbazepine GlucuronidationAna I. Loureiro, Carlos Fernandes-Lopes, Maria J. Bonifácio, Lyndon C. Wright and Patricio Soares-da-SilvaDrug Metabolism and Disposition September 2011, 39 (9) 1486-1494; DOI: https://doi.org/10.1124/dmd.111.038620
Strohalm, Jiří
- You have accessInteraction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free DoxorubicinVlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel AnzenbacherDrug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986
Su, Hong
- You have accessIn Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor InhibitorHaizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
Sugiyama, Yuichi
- You have accessCulture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human HepatocytesNaoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
Sun, Lifang
- You have accessEfficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical SpaceJelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. CommandeurDrug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
Sun, Q.
- You have access1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-AcetyltransferaseQ. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. MaratheDrug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
Sweatman, Trevor
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
Sychterz, Caroline
- You have accessInvestigations of Hydrazine Cleavage of Eltrombopag in HumansYanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
T
Takahashi, Masakatsu
- You have accessImpact of Intestinal Glucuronidation on the Pharmacokinetics of RaloxifeneKeigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki KumeDrug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
Takeba, Naomi
- You have accessImpact of Intestinal Glucuronidation on the Pharmacokinetics of RaloxifeneKeigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki KumeDrug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
Takezawa, Toshiaki
- You have accessCulture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human HepatocytesNaoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
Takiguchi, Masufumi
- You have accessNovel Pathway of Metabolic Activation of Bisphenol A-Related Compounds for Estrogenic ActivityKatsuhiro Okuda, Tomoko Fukuuchi, Masufumi Takiguchi and Shin'ichi YoshiharaDrug Metabolism and Disposition September 2011, 39 (9) 1696-1703; DOI: https://doi.org/10.1124/dmd.111.040121
Talley, Kimberly
- You have accessInvestigations of Hydrazine Cleavage of Eltrombopag in HumansYanli Deng, Martin Rogers, Caroline Sychterz, Kimberly Talley, Yanwen Qian, David Bershas, May Ho, Wei Shi, Emile P. Chen, Cosette Serabjit-Singh and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1747-1754; DOI: https://doi.org/10.1124/dmd.111.040188
Tan, Beijing
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
Tanimoto, Tomohiko
- You have accessImpact of Intestinal Glucuronidation on the Pharmacokinetics of RaloxifeneKeigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki KumeDrug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
Tsalta, Catherine D.
- You have accessMetabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent BindingCatherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
Tsuda-Tsukimoto, Minoru
- You have accessImpact of Intestinal Glucuronidation on the Pharmacokinetics of RaloxifeneKeigo Kosaka, Norifumi Sakai, Yuya Endo, Yuga Fukuhara, Minoru Tsuda-Tsukimoto, Tatsuyuki Ohtsuka, Ichiro Kino, Tomohiko Tanimoto, Naomi Takeba, Masakatsu Takahashi and Toshiyuki KumeDrug Metabolism and Disposition September 2011, 39 (9) 1495-1502; DOI: https://doi.org/10.1124/dmd.111.040030
Tuckey, Robert C.
- You have accessProduction of 22-Hydroxy Metabolites of Vitamin D3 by Cytochrome P450scc (CYP11A1) and Analysis of Their Biological Activities on Skin CellsRobert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri and Andrzej SlominskiDrug Metabolism and Disposition September 2011, 39 (9) 1577-1588; DOI: https://doi.org/10.1124/dmd.111.040071
Tugnait, Meera
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
U
Uhlig, Silvio
- You have accessIn Vitro Metabolism of the Mycotoxin Enniatin B in Different Species and Cytochrome P450 Enzyme Phenotyping by Chemical InhibitorsChristiane K. Fæste, Lada Ivanova and Silvio UhligDrug Metabolism and Disposition September 2011, 39 (9) 1768-1776; DOI: https://doi.org/10.1124/dmd.111.039529
Ulbrich, Karel
- You have accessInteraction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free DoxorubicinVlastimil Mašek, Eva Anzenbacherová, Tomáš Etrych, Jiří Strohalm, Karel Ulbrich and Pavel AnzenbacherDrug Metabolism and Disposition September 2011, 39 (9) 1704-1710; DOI: https://doi.org/10.1124/dmd.110.037986
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VandenBrink, Brooke M.
- You have accessEvaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe SubstrateBrooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. WahlstromDrug Metabolism and Disposition September 2011, 39 (9) 1546-1554; DOI: https://doi.org/10.1124/dmd.111.039065
van Leeuwen, Jolanda S.
- You have accessEfficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical SpaceJelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. CommandeurDrug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
Venitz, Jürgen
- You have accessPreclinical Disposition (In Vitro) of Novel μ-Opioid Receptor Selective AntagonistsPallabi Mitra, Jürgen Venitz, Yunyun Yuan, Yan Zhang and Phillip M. GerkDrug Metabolism and Disposition September 2011, 39 (9) 1589-1596; DOI: https://doi.org/10.1124/dmd.111.038588
Venner, Monica
- You have accessOral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in FoalsJette Peters, Wiebke Block, Stefan Oswald, Johanna Freyer, Markus Grube, Heyo K. Kroemer, Marc Lämmer, Dieter Lütjohann, Monica Venner and Werner SiegmundDrug Metabolism and Disposition September 2011, 39 (9) 1643-1649; DOI: https://doi.org/10.1124/dmd.111.039206
Vermeulen, Nico P. E.
- You have accessEfficient Screening of Cytochrome P450 BM3 Mutants for Their Metabolic Activity and Diversity toward a Wide Set of Drug-Like Molecules in Chemical SpaceJelle Reinen, Jolanda S. van Leeuwen, Yongmin Li, Lifang Sun, Peter D. J. Grootenhuis, Caroline J. Decker, John Saunders, Nico P. E. Vermeulen and Jan N. M. CommandeurDrug Metabolism and Disposition September 2011, 39 (9) 1568-1576; DOI: https://doi.org/10.1124/dmd.111.039461
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Wahlstrom, Jan L.
- You have accessEvaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe SubstrateBrooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. WahlstromDrug Metabolism and Disposition September 2011, 39 (9) 1546-1554; DOI: https://doi.org/10.1124/dmd.111.039065
Walsky, Robert L.
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
Wang, Qing
- You have accessFrom Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in RatsCheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min YeDrug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695
Wang, Weirong
- You have accessMonoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic ConsequencesWeirong Wang, Ping Lu, Yulin Fang, Lora Hamuro, Tamara Pittman, Brian Carr, Jerome Hochman and Thomayant PrueksaritanontDrug Metabolism and Disposition September 2011, 39 (9) 1469-1477; DOI: https://doi.org/10.1124/dmd.111.039453
Watanabe, Takao
- You have accessCulture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human HepatocytesNaoki Kotani, Kazuya Maeda, Takao Watanabe, Mariko Hiramatsu, Li-kun Gong, Yi-an Bi, Toshiaki Takezawa, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition September 2011, 39 (9) 1503-1510; DOI: https://doi.org/10.1124/dmd.111.038968
Wen, Bo
- You have accessBioactivation of Glafenine by Human Liver Microsomes and Peroxidases: Identification of Electrophilic Iminoquinone Species and GSH ConjugatesBo Wen and David J. MooreDrug Metabolism and Disposition September 2011, 39 (9) 1511-1521; DOI: https://doi.org/10.1124/dmd.111.039396
White, Sarah
- You have accessGestation Time-Dependent Pharmacokinetics of Intravenous (+)-Methamphetamine in RatsSarah White, Elizabeth Laurenzana, Howard Hendrickson, W. Brooks Gentry and S. Michael OwensDrug Metabolism and Disposition September 2011, 39 (9) 1718-1726; DOI: https://doi.org/10.1124/dmd.111.039446
Wienkers, Larry C.
- You have accessEvaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe SubstrateBrooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. WahlstromDrug Metabolism and Disposition September 2011, 39 (9) 1546-1554; DOI: https://doi.org/10.1124/dmd.111.039065
Williams, Daphne
- You have accessMetabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
Williams, J. Andrew
- You have accessApplication of the Fluorescent Probe 1-Anilinonaphthalene-8-Sulfonate to the Measurement of the Nonspecific Binding of Drugs to Human Liver MicrosomesJames A. McLure, Donald J. Birkett, David J. Elliot, J. Andrew Williams, Andrew Rowland and John O. MinersDrug Metabolism and Disposition September 2011, 39 (9) 1711-1717; DOI: https://doi.org/10.1124/dmd.111.039354
Wire, Mary Beth
- You have accessMetabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYanli Deng, Armina Madatian, Mary Beth Wire, Carolyn Bowen, Jung Wook Park, Daphne Williams, Bin Peng, Ernest Schubert, Frances Gorycki, Mark Levy and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1734-1746; DOI: https://doi.org/10.1124/dmd.111.040170
Wright, Lyndon C.
- You have accessHepatic UDP-Glucuronosyltransferase Is Responsible for Eslicarbazepine GlucuronidationAna I. Loureiro, Carlos Fernandes-Lopes, Maria J. Bonifácio, Lyndon C. Wright and Patricio Soares-da-SilvaDrug Metabolism and Disposition September 2011, 39 (9) 1486-1494; DOI: https://doi.org/10.1124/dmd.111.038620
Wright, Stephen H.
- You have accessCharacterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In VivoYaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn SipesDrug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
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Xia, Fangming
- You have accessMetabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent BindingCatherine D. Tsalta, Armina Madatian, Ernest M. Schubert, Fangming Xia, William M. Hardesty, Yanli Deng, Jennifer L. Seymour and Peter D. GoryckiDrug Metabolism and Disposition September 2011, 39 (9) 1620-1632; DOI: https://doi.org/10.1124/dmd.110.036467
Xiang, Cheng
- You have accessFrom Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in RatsCheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min YeDrug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695
Y
Yang, Xin
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
Yao, Ming
- You have accessIn Vitro Characterization of the Metabolic Pathways and Cytochrome P450 Inhibition and Induction Potential of BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor InhibitorHaizheng Hong, Hong Su, Li Ma, Ming Yao, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition September 2011, 39 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.111.039776
Yasuda, Kaori
- You have accessSequential Metabolism of Sesamin by Cytochrome P450 and UDP-Glucuronosyltransferase in Human LiverKaori Yasuda, Shinichi Ikushiro, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition September 2011, 39 (9) 1538-1545; DOI: https://doi.org/10.1124/dmd.111.039875
Ye, Min
- You have accessFrom Single Compounds to Herbal Extract: A Strategy to Systematically Characterize the Metabolites of Licorice in RatsCheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo and Min YeDrug Metabolism and Disposition September 2011, 39 (9) 1597-1608; DOI: https://doi.org/10.1124/dmd.111.038695
Yoshihara, Shin'ichi
- You have accessNovel Pathway of Metabolic Activation of Bisphenol A-Related Compounds for Estrogenic ActivityKatsuhiro Okuda, Tomoko Fukuuchi, Masufumi Takiguchi and Shin'ichi YoshiharaDrug Metabolism and Disposition September 2011, 39 (9) 1696-1703; DOI: https://doi.org/10.1124/dmd.111.040121
Yuan, Yunyun
- You have accessPreclinical Disposition (In Vitro) of Novel μ-Opioid Receptor Selective AntagonistsPallabi Mitra, Jürgen Venitz, Yunyun Yuan, Yan Zhang and Phillip M. GerkDrug Metabolism and Disposition September 2011, 39 (9) 1589-1596; DOI: https://doi.org/10.1124/dmd.111.038588
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Zhang, L.
- You have access1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-AcetyltransferaseQ. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues and P. MaratheDrug Metabolism and Disposition September 2011, 39 (9) 1674-1679; DOI: https://doi.org/10.1124/dmd.111.039834
Zhang, Yan
- You have accessPreclinical Disposition (In Vitro) of Novel μ-Opioid Receptor Selective AntagonistsPallabi Mitra, Jürgen Venitz, Yunyun Yuan, Yan Zhang and Phillip M. GerkDrug Metabolism and Disposition September 2011, 39 (9) 1589-1596; DOI: https://doi.org/10.1124/dmd.111.038588
Zhu, Tong
- You have accessPreclinical Species and Human Disposition of PF-04971729, a Selective Inhibitor of the Sodium-Dependent Glucose Cotransporter 2 and Clinical Candidate for the Treatment of Type 2 Diabetes MellitusAmit S. Kalgutkar, Meera Tugnait, Tong Zhu, Emi Kimoto, Zhuang Miao, Vincent Mascitti, Xin Yang, Beijing Tan, Robert L. Walsky, Jonathan Chupka, Bo Feng and Ralph P. RobinsonDrug Metabolism and Disposition September 2011, 39 (9) 1609-1619; DOI: https://doi.org/10.1124/dmd.111.040675
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