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Research ArticleArticle

Characterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In Vivo

Yaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn Sipes
Drug Metabolism and Disposition September 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865

Article Information

vol. 39 no. 9 1755-1761
DOI 
https://doi.org/10.1124/dmd.110.035865
PubMed 
21646436
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 13, 2010
  • Accepted June 1, 2011
  • Published online August 19, 2011.

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Copyright & Usage 
U.S. Government work not protected by U.S. copyright

Author Information

  1. Yaofeng Cheng,
  2. Lucy J. Martinez-Guerrero,
  3. Stephen H. Wright,
  4. Robert K. Kuester,
  5. Michelle J. Hooth and
  6. I. Glenn Sipes
  1. Departments of Pharmacology (Y.C., R.K.K., I.G.S.) and Physiology (L.J.M.-G., S.H.W.), College of Medicine, the University of Arizona, Tucson, Arizona; and National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina (M.J.H.)
  1. Address correspondence to:
    Dr. I. Glenn Sipes, Department of Pharmacology, College of Medicine, The University of Arizona, P.O. Box 245050, Tucson, AZ 85724-5050. E-mail: sipes{at}email.arizona.edu
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Research ArticleArticle

Characterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In Vivo

Yaofeng Cheng, Lucy J. Martinez-Guerrero, Stephen H. Wright, Robert K. Kuester, Michelle J. Hooth and I. Glenn Sipes
Drug Metabolism and Disposition September 1, 2011, 39 (9) 1755-1761; DOI: https://doi.org/10.1124/dmd.110.035865
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