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Drug Metabolism & Disposition

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Table of Contents

July 01, 1976; Volume 4,Issue 4
  • You have access
    Lipid binding of a halothane metabolite. Relationship to lipid peroxidation in vitro.
    C L Wood, A J Gandolfi and R A Van Dyke
    Drug Metabolism and Disposition July 1976, 4 (4) 305-313;
  • You have access
    Studies on the mechanism of toxicity and of development of tolerance to the pulmonary toxin, alpha-naphthylthiourea (ANTU).
    M R Boyd and R A Neal
    Drug Metabolism and Disposition July 1976, 4 (4) 314-322;
  • You have access
    Stereospecific binding of timolol, a beta-adrenergic blocking agent.
    D J Tocco, K F Hooke, F A Deluna and A E Duncan
    Drug Metabolism and Disposition July 1976, 4 (4) 323-329;
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    Inversion of optical configuration of alpha-methylfluorene-2-acetic acid (cicloprofen) in rats and monkeys.
    S J Lan, K J Kripalani, A V Dean, P Egli, L T Difazio and E C Schreiber
    Drug Metabolism and Disposition July 1976, 4 (4) 330-339;
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    Buffer catalysis of the racemization reaction of some 5-phenylhydantoins and its relation to the in vivo metabolism of ethotoin.
    K H Dudley and D L Bius
    Drug Metabolism and Disposition July 1976, 4 (4) 340-348;
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    5,5-Bis(3-hydroxyphenyl)hydantoin, a minor metabolite of diphenylhydantoin (dilantin) in the rat and human.
    R M Thompson, J Beghin, W K Fife and N Gerber
    Drug Metabolism and Disposition July 1976, 4 (4) 349-356;
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    Metabolism of dihalomethanes to formaldehyde and inorganic halide. I. In vitro studies.
    A E Ahmed and M W Anders
    Drug Metabolism and Disposition July 1976, 4 (4) 357-361;
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    Metabolism of 2,4,5,2',5'-pentachlorobiphenyl in the rat. Qualitative and quantitative aspects.
    P R Chen, J D McKinney and H B Matthews
    Drug Metabolism and Disposition July 1976, 4 (4) 362-367;
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    3-(Hydroxymethyl)-8-methoxychromone and unconjugated metabolites in rat plasma. Identification of the biologically active species.
    F J De Carlo, D J Herzig, E J Kusner, P R Schumann, M D Melgar, S George and M C Crew
    Drug Metabolism and Disposition July 1976, 4 (4) 368-371;
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    Metabolism of tripelennamine in man.
    N K Chaudhuri, O A Servando, M J Manniello, R C Luders, D K Chao and M F Bartlett
    Drug Metabolism and Disposition July 1976, 4 (4) 372-378;
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    Disposition and metabolism of 3-(3-chlorophenoxy)-N-methylpyrrolidine [14C]-carboxamide in the rat, dog, and man.
    L B Turnbull, L Teng, J Newman, R B Bruce and W R Maynard
    Drug Metabolism and Disposition July 1976, 4 (4) 379-386;
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    Physiological disposition and metabolic fate of a new antiarrhythmic agent, alpha, alpha-dimethyl-4-(alpha, alpha, beta, beta-tetrafluorophenethyl) benzylamine in the rat, dog, monkey, baboon, and man.
    A G Zacchei, L L Weidner, G H Besselaar and E B Raftery
    Drug Metabolism and Disposition July 1976, 4 (4) 387-401;
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    Effect of 3-methylcholanthrene pretreatment on the bioavailability of phenacetin in the rat.
    R M Welch, C R Hughes and R L Deangelis
    Drug Metabolism and Disposition July 1976, 4 (4) 402-406;
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    Effect of methadone dose on the biliary excretion of methadone metabolites in the rat.
    D L Roerig, A T Hasegawa and R I Wang
    Drug Metabolism and Disposition July 1976, 4 (4) 407-412;
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In this issue

Drug Metabolism and Disposition
Vol. 4, Issue 4
1 Jul 1976
  • Table of Contents
  • Index by author
  • Back Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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