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Drug Metabolism & Disposition

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Table of Contents

September 01, 1976; Volume 4,Issue 5
  • You have access
    Polyamines and drug oxidations.
    S K Chapman
    Drug Metabolism and Disposition September 1976, 4 (5) 417-422;
  • You have access
    Drug biotransformation in microsomes from the fetal stumptailed macaque, Macaca arctoides: hepatic N-demethylation.
    B H Dvorchik, V G Stenger and S L Quattropani
    Drug Metabolism and Disposition September 1976, 4 (5) 423;
  • You have access
    N-Hydroxylation of phenacetin by hamster liver microsomes.
    J A Hinson and J R Mitchell
    Drug Metabolism and Disposition September 1976, 4 (5) 430-435;
  • You have access
    Properties of microsomal enzyme systems that reduce N-hydroxyphentermine.
    C Y Sum and A K Cho
    Drug Metabolism and Disposition September 1976, 4 (5) 436-441;
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    Cytochrome P-450 content and mixed-function oxidase activity in microsomes isolated from mouse skin.
    R J Pohl, R M Philpot and J R Fouts
    Drug Metabolism and Disposition September 1976, 4 (5) 442-450;
  • You have access
    Preservation of various microsomal drug metabolizing components in tissue preparations from the livers, lungs, and small intestines of rodents.
    J M Tredger and R S Chhabra
    Drug Metabolism and Disposition September 1976, 4 (5) 451-459;
  • You have access
    Role of blood flow in carbon monoxide- and hypoxic hypoxia-induced alterations in hexobarbital metabolism in rats.
    R A Roth and R J Rubin
    Drug Metabolism and Disposition September 1976, 4 (5) 460-467;
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    The time course of tolmetin and its metabolites in the plasma of individual rats and mice.
    B H Migdalof, K A Yorgey and C G Popkave
    Drug Metabolism and Disposition September 1976, 4 (5) 468-473;
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    The urinary excretion profiles of naltrexone in man, monkey, rabbit, and rat.
    H E Dayton and C E Inturrisi
    Drug Metabolism and Disposition September 1976, 4 (5) 474-478;
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    The biotransformation of (6,7-dichloro-2-methyl-1-oxo-2-phenyl-5-indanyloxy) acetic acid (MK-196) in the chimpanzee.
    A G Zacchei, T I Wishousky, B H Arison and G M Fanelli
    Drug Metabolism and Disposition September 1976, 4 (5) 479-489;
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    The physiological disposition of the uricosuric-saluretic agent (6,7-dichloro-2-methyl-1-oxo-2-phenyl-5-indanyloxy)acetic acid (MK-196) in the rat, dog, and monkey.
    A G Zacchei and T I Wishousky
    Drug Metabolism and Disposition September 1976, 4 (5) 490-498;
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    Biliary copper excretion in the rat is enhanced by spironolactone.
    J E Haddow and R Lester
    Drug Metabolism and Disposition September 1976, 4 (5) 499-503;
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    The secretion of methadone and its major metabolite in the gastric juice of humans: comparison with blood and salivary concentrations.
    R K Lynn, G D Olsen, R M Leger, W P Gordon, R G Smith and N Gerber
    Drug Metabolism and Disposition September 1976, 4 (5) 504-509;
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In this issue

Drug Metabolism and Disposition
Vol. 4, Issue 5
1 Sep 1976
  • Table of Contents
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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