Index by author
January 01, 2012; Volume 40,Issue 1
B
Barber, Jane
- You have accessIn Vitro Inhibition of the Bile Salt Export Pump Correlates with Risk of Cholestatic Drug-Induced Liver Injury in HumansSarah Dawson, Simone Stahl, Nikki Paul, Jane Barber and J. Gerald KennaDrug Metabolism and Disposition January 2012, 40 (1) 130-138; DOI: https://doi.org/10.1124/dmd.111.040758
Baucom, Christie C.
- You have accessSpecies-Dependent and Receptor-Selective Action of Bilobalide on the Function of Constitutive Androstane Receptor and Pregnane X ReceptorAik Jiang Lau, Guixiang Yang, Ganesh Rajaraman, Christie C. Baucom and Thomas K. H. ChangDrug Metabolism and Disposition January 2012, 40 (1) 178-186; DOI: https://doi.org/10.1124/dmd.111.042879
Beauchemin, Stéphanie
- You have accessEffects of Chronic Renal Failure on Brain Drug Transporters in RatsJudith Naud, Louis-Philippe Laurin, Josée Michaud, Stéphanie Beauchemin, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition January 2012, 40 (1) 39-46; DOI: https://doi.org/10.1124/dmd.111.041145
Bell, Jordan C.
- You have accessRegulation of Cytochrome P450 4F11 by Nuclear Transcription Factor-κBJordan C. Bell and Henry W. StrobelDrug Metabolism and Disposition January 2012, 40 (1) 205-211; DOI: https://doi.org/10.1124/dmd.111.041178
Black, John Logan
- You have accessFrequency of Undetected CYP2D6 Hybrid Genes in Clinical Samples: Impact on Phenotype PredictionJohn Logan Black, Denise L. Walker, Dennis J. O'Kane and Maria HarmandayanDrug Metabolism and Disposition January 2012, 40 (1) 111-119; DOI: https://doi.org/10.1124/dmd.111.040832
Bligh, S. W. Annie
- You have accessDebrisoquine Metabolism and CYP2D Expression in Marmoset Liver MicrosomesBrian R. Cooke, S. W. Annie Bligh, Z. Richard Cybulski, Costas Ioannides and Michael HallDrug Metabolism and Disposition January 2012, 40 (1) 70-75; DOI: https://doi.org/10.1124/dmd.111.041566
Borts, David J.
- You have accessHuman Metabolism of Lapatinib, a Dual Kinase Inhibitor: Implications for HepatotoxicityStephen Castellino, Michael O'Mara, Kevin Koch, David J. Borts, Gary D. Bowers and Christopher MacLauchlinDrug Metabolism and Disposition January 2012, 40 (1) 139-150; DOI: https://doi.org/10.1124/dmd.111.040949
Boulenc, Xavier
- You have accessEffects of Omeprazole and Genetic Polymorphism of CYP2C19 on the Clopidogrel Active MetaboliteXavier Boulenc, Nassim Djebli, Juan Shi, Laurent Perrin, William Brian, Robert Van Horn and Fabrice HurbinDrug Metabolism and Disposition January 2012, 40 (1) 187-197; DOI: https://doi.org/10.1124/dmd.111.040394
Bowers, Gary D.
- You have accessHuman Metabolism of Lapatinib, a Dual Kinase Inhibitor: Implications for HepatotoxicityStephen Castellino, Michael O'Mara, Kevin Koch, David J. Borts, Gary D. Bowers and Christopher MacLauchlinDrug Metabolism and Disposition January 2012, 40 (1) 139-150; DOI: https://doi.org/10.1124/dmd.111.040949
Brian, William
- You have accessEffects of Omeprazole and Genetic Polymorphism of CYP2C19 on the Clopidogrel Active MetaboliteXavier Boulenc, Nassim Djebli, Juan Shi, Laurent Perrin, William Brian, Robert Van Horn and Fabrice HurbinDrug Metabolism and Disposition January 2012, 40 (1) 187-197; DOI: https://doi.org/10.1124/dmd.111.040394
Brouwer, Kim L. R.
- You have accessA Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite PairGrace Zhixia Yan, Claudia N. Generaux, Miyoung Yoon, Rachel B. Goldsmith, Richard R. Tidwell, James E. Hall, Carol A. Olson, Harvey J. Clewell, Kim L. R. Brouwer and Mary F. PaineDrug Metabolism and Disposition January 2012, 40 (1) 6-17; DOI: https://doi.org/10.1124/dmd.111.040063
C
Cai, Jian
- You have accessPhenotype of the Most Common “Slow Acetylator” Arylamine N-Acetyltransferase 1 Genetic Variant (NAT1*14B) Is Substrate-DependentLori M. Millner, Mark A. Doll, Jian Cai, J. Christopher States and David W. HeinDrug Metabolism and Disposition January 2012, 40 (1) 198-204; DOI: https://doi.org/10.1124/dmd.111.041855
Caradonna, Nicola Pasquale
- You have accessComparison of Cryopreserved HepaRG Cells with Cryopreserved Human Hepatocytes for Prediction of Clearance for 26 DrugsUgo Zanelli, Nicola Pasquale Caradonna, David Hallifax, Elisa Turlizzi and J. Brian HoustonDrug Metabolism and Disposition January 2012, 40 (1) 104-110; DOI: https://doi.org/10.1124/dmd.111.042309
Castellino, Stephen
- You have accessHuman Metabolism of Lapatinib, a Dual Kinase Inhibitor: Implications for HepatotoxicityStephen Castellino, Michael O'Mara, Kevin Koch, David J. Borts, Gary D. Bowers and Christopher MacLauchlinDrug Metabolism and Disposition January 2012, 40 (1) 139-150; DOI: https://doi.org/10.1124/dmd.111.040949
Chang, Thomas K. H.
- You have accessSpecies-Dependent and Receptor-Selective Action of Bilobalide on the Function of Constitutive Androstane Receptor and Pregnane X ReceptorAik Jiang Lau, Guixiang Yang, Ganesh Rajaraman, Christie C. Baucom and Thomas K. H. ChangDrug Metabolism and Disposition January 2012, 40 (1) 178-186; DOI: https://doi.org/10.1124/dmd.111.042879
Claessens, Adam J.
- You have accessPotential Contribution of Cytochrome P450 2B6 to Hepatic 4-Hydroxycyclophosphamide Formation In Vitro and In VivoBrianne S. Raccor, Adam J. Claessens, Jean C. Dinh, Julie R. Park, Douglas S. Hawkins, Sushma S. Thomas, Karen W. Makar, Jeannine S. McCune and Rheem A. TotahDrug Metabolism and Disposition January 2012, 40 (1) 54-63; DOI: https://doi.org/10.1124/dmd.111.039347
Claude, Nancy
- You have accessInterindividual Variability in Gene Expression Profiles in Human Hepatocytes and Comparison with HepaRG CellsAlexandra Rogue, Carine Lambert, Catherine Spire, Nancy Claude and André GuillouzoDrug Metabolism and Disposition January 2012, 40 (1) 151-158; DOI: https://doi.org/10.1124/dmd.111.042028
Clewell, Harvey J.
- You have accessA Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite PairGrace Zhixia Yan, Claudia N. Generaux, Miyoung Yoon, Rachel B. Goldsmith, Richard R. Tidwell, James E. Hall, Carol A. Olson, Harvey J. Clewell, Kim L. R. Brouwer and Mary F. PaineDrug Metabolism and Disposition January 2012, 40 (1) 6-17; DOI: https://doi.org/10.1124/dmd.111.040063
Cooke, Brian R.
- You have accessDebrisoquine Metabolism and CYP2D Expression in Marmoset Liver MicrosomesBrian R. Cooke, S. W. Annie Bligh, Z. Richard Cybulski, Costas Ioannides and Michael HallDrug Metabolism and Disposition January 2012, 40 (1) 70-75; DOI: https://doi.org/10.1124/dmd.111.041566
Cybulski, Z. Richard
- You have accessDebrisoquine Metabolism and CYP2D Expression in Marmoset Liver MicrosomesBrian R. Cooke, S. W. Annie Bligh, Z. Richard Cybulski, Costas Ioannides and Michael HallDrug Metabolism and Disposition January 2012, 40 (1) 70-75; DOI: https://doi.org/10.1124/dmd.111.041566
D
Dawson, Sarah
- You have accessIn Vitro Inhibition of the Bile Salt Export Pump Correlates with Risk of Cholestatic Drug-Induced Liver Injury in HumansSarah Dawson, Simone Stahl, Nikki Paul, Jane Barber and J. Gerald KennaDrug Metabolism and Disposition January 2012, 40 (1) 130-138; DOI: https://doi.org/10.1124/dmd.111.040758
Desbans, Coraline
- You have accessBupropion Hydroxylation as a Selective Marker of Rat CYP2B1 Catalytic ActivityDumrongsak Pekthong, Coraline Desbans, Hélène Martin and Lysiane RichertDrug Metabolism and Disposition January 2012, 40 (1) 32-38; DOI: https://doi.org/10.1124/dmd.111.041368
Dinh, Jean C.
- You have accessPotential Contribution of Cytochrome P450 2B6 to Hepatic 4-Hydroxycyclophosphamide Formation In Vitro and In VivoBrianne S. Raccor, Adam J. Claessens, Jean C. Dinh, Julie R. Park, Douglas S. Hawkins, Sushma S. Thomas, Karen W. Makar, Jeannine S. McCune and Rheem A. TotahDrug Metabolism and Disposition January 2012, 40 (1) 54-63; DOI: https://doi.org/10.1124/dmd.111.039347
Djebli, Nassim
- You have accessEffects of Omeprazole and Genetic Polymorphism of CYP2C19 on the Clopidogrel Active MetaboliteXavier Boulenc, Nassim Djebli, Juan Shi, Laurent Perrin, William Brian, Robert Van Horn and Fabrice HurbinDrug Metabolism and Disposition January 2012, 40 (1) 187-197; DOI: https://doi.org/10.1124/dmd.111.040394
Doll, Mark A.
- You have accessPhenotype of the Most Common “Slow Acetylator” Arylamine N-Acetyltransferase 1 Genetic Variant (NAT1*14B) Is Substrate-DependentLori M. Millner, Mark A. Doll, Jian Cai, J. Christopher States and David W. HeinDrug Metabolism and Disposition January 2012, 40 (1) 198-204; DOI: https://doi.org/10.1124/dmd.111.041855
E
Ebner, Thomas
- You have accessSimultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and ActivitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Naoki Ishiguro, Wataru Kishimoto, Eva Ludwig-Schwellinger, Thomas Ebner and Tetsuya TerasakiDrug Metabolism and Disposition January 2012, 40 (1) 83-92; DOI: https://doi.org/10.1124/dmd.111.042259
- You have accessAbsolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human HepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Atsushi Sakamoto, Naoki Ishiguro, Takehisa Matsumaru, Tetsuya Terasaki and Thomas EbnerDrug Metabolism and Disposition January 2012, 40 (1) 93-103; DOI: https://doi.org/10.1124/dmd.111.042275
Ellison, Corie A.
- You have accessHuman Hepatic Cytochrome P450-Specific Metabolism of the Organophosphorus Pesticides Methyl Parathion and DiazinonCorie A. Ellison, Yuan Tian, James B. Knaak, Paul J. Kostyniak and James R. OlsonDrug Metabolism and Disposition January 2012, 40 (1) 1-5; DOI: https://doi.org/10.1124/dmd.111.042572
F
Felmlee, Melanie A.
- You have accessγ-Hydroxybutyrate Blood/Plasma Partitioning: Effect of Physiologic pH on Transport by Monocarboxylate TransportersBridget L. Morse, Melanie A. Felmlee and Marilyn E. MorrisDrug Metabolism and Disposition January 2012, 40 (1) 64-69; DOI: https://doi.org/10.1124/dmd.111.041285
- You have accessBrain Uptake of the Drug of Abuse γ-Hydroxybutyric Acid in RatsSamuel A. Roiko, Melanie A. Felmlee and Marilyn E. MorrisDrug Metabolism and Disposition January 2012, 40 (1) 212-218; DOI: https://doi.org/10.1124/dmd.111.041749
Foti, Robert S.
- You have accessPrediction of CYP2D6 Drug Interactions from In Vitro Data: Evidence for Substrate-Dependent InhibitionBrooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. WahlstromDrug Metabolism and Disposition January 2012, 40 (1) 47-53; DOI: https://doi.org/10.1124/dmd.111.041210
Franze, B.
- You have accessIn Vitro Glucuronidation of the Antibacterial Triclocarban and Its Oxidative MetabolitesN. H. Schebb, B. Franze, R. Maul, A. Ranganathan and B. D. HammockDrug Metabolism and Disposition January 2012, 40 (1) 25-31; DOI: https://doi.org/10.1124/dmd.111.042283
Fujiyama, Yoichi
- You have accessAcetaminophen-Induced Hepatotoxicity in a Liver Tissue Model Consisting of Primary Hepatocytes Assembling around an Endothelial Cell NetworkYu Toyoda, Miho Tamai, Kasumi Kashikura, Shunsuke Kobayashi, Yoichi Fujiyama, Tomoyoshi Soga and Yoh-ichi TagawaDrug Metabolism and Disposition January 2012, 40 (1) 169-177; DOI: https://doi.org/10.1124/dmd.111.041137
G
Gan, Jinping
- You have accessIdentification of the Oxidative and Conjugative Enzymes Involved in the Biotransformation of BrivanibJiachang Gong, Jinping Gan and Ramaswamy A. IyerDrug Metabolism and Disposition January 2012, 40 (1) 219-226; DOI: https://doi.org/10.1124/dmd.111.042457
Generaux, Claudia N.
- You have accessA Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite PairGrace Zhixia Yan, Claudia N. Generaux, Miyoung Yoon, Rachel B. Goldsmith, Richard R. Tidwell, James E. Hall, Carol A. Olson, Harvey J. Clewell, Kim L. R. Brouwer and Mary F. PaineDrug Metabolism and Disposition January 2012, 40 (1) 6-17; DOI: https://doi.org/10.1124/dmd.111.040063
Goldsmith, Rachel B.
- You have accessA Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite PairGrace Zhixia Yan, Claudia N. Generaux, Miyoung Yoon, Rachel B. Goldsmith, Richard R. Tidwell, James E. Hall, Carol A. Olson, Harvey J. Clewell, Kim L. R. Brouwer and Mary F. PaineDrug Metabolism and Disposition January 2012, 40 (1) 6-17; DOI: https://doi.org/10.1124/dmd.111.040063
Gong, Jiachang
- You have accessIdentification of the Oxidative and Conjugative Enzymes Involved in the Biotransformation of BrivanibJiachang Gong, Jinping Gan and Ramaswamy A. IyerDrug Metabolism and Disposition January 2012, 40 (1) 219-226; DOI: https://doi.org/10.1124/dmd.111.042457
Guillouzo, André
- You have accessInterindividual Variability in Gene Expression Profiles in Human Hepatocytes and Comparison with HepaRG CellsAlexandra Rogue, Carine Lambert, Catherine Spire, Nancy Claude and André GuillouzoDrug Metabolism and Disposition January 2012, 40 (1) 151-158; DOI: https://doi.org/10.1124/dmd.111.042028
H
Hall, James E.
- You have accessA Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite PairGrace Zhixia Yan, Claudia N. Generaux, Miyoung Yoon, Rachel B. Goldsmith, Richard R. Tidwell, James E. Hall, Carol A. Olson, Harvey J. Clewell, Kim L. R. Brouwer and Mary F. PaineDrug Metabolism and Disposition January 2012, 40 (1) 6-17; DOI: https://doi.org/10.1124/dmd.111.040063
Hall, Michael
- You have accessDebrisoquine Metabolism and CYP2D Expression in Marmoset Liver MicrosomesBrian R. Cooke, S. W. Annie Bligh, Z. Richard Cybulski, Costas Ioannides and Michael HallDrug Metabolism and Disposition January 2012, 40 (1) 70-75; DOI: https://doi.org/10.1124/dmd.111.041566
Hallifax, David
- You have accessComparison of Cryopreserved HepaRG Cells with Cryopreserved Human Hepatocytes for Prediction of Clearance for 26 DrugsUgo Zanelli, Nicola Pasquale Caradonna, David Hallifax, Elisa Turlizzi and J. Brian HoustonDrug Metabolism and Disposition January 2012, 40 (1) 104-110; DOI: https://doi.org/10.1124/dmd.111.042309
Hammock, B. D.
- You have accessIn Vitro Glucuronidation of the Antibacterial Triclocarban and Its Oxidative MetabolitesN. H. Schebb, B. Franze, R. Maul, A. Ranganathan and B. D. HammockDrug Metabolism and Disposition January 2012, 40 (1) 25-31; DOI: https://doi.org/10.1124/dmd.111.042283
Harmandayan, Maria
- You have accessFrequency of Undetected CYP2D6 Hybrid Genes in Clinical Samples: Impact on Phenotype PredictionJohn Logan Black, Denise L. Walker, Dennis J. O'Kane and Maria HarmandayanDrug Metabolism and Disposition January 2012, 40 (1) 111-119; DOI: https://doi.org/10.1124/dmd.111.040832
Hawkins, Douglas S.
- You have accessPotential Contribution of Cytochrome P450 2B6 to Hepatic 4-Hydroxycyclophosphamide Formation In Vitro and In VivoBrianne S. Raccor, Adam J. Claessens, Jean C. Dinh, Julie R. Park, Douglas S. Hawkins, Sushma S. Thomas, Karen W. Makar, Jeannine S. McCune and Rheem A. TotahDrug Metabolism and Disposition January 2012, 40 (1) 54-63; DOI: https://doi.org/10.1124/dmd.111.039347
Hein, David W.
- You have accessPhenotype of the Most Common “Slow Acetylator” Arylamine N-Acetyltransferase 1 Genetic Variant (NAT1*14B) Is Substrate-DependentLori M. Millner, Mark A. Doll, Jian Cai, J. Christopher States and David W. HeinDrug Metabolism and Disposition January 2012, 40 (1) 198-204; DOI: https://doi.org/10.1124/dmd.111.041855
Houston, J. Brian
- You have accessComparison of Cryopreserved HepaRG Cells with Cryopreserved Human Hepatocytes for Prediction of Clearance for 26 DrugsUgo Zanelli, Nicola Pasquale Caradonna, David Hallifax, Elisa Turlizzi and J. Brian HoustonDrug Metabolism and Disposition January 2012, 40 (1) 104-110; DOI: https://doi.org/10.1124/dmd.111.042309
Hurbin, Fabrice
- You have accessEffects of Omeprazole and Genetic Polymorphism of CYP2C19 on the Clopidogrel Active MetaboliteXavier Boulenc, Nassim Djebli, Juan Shi, Laurent Perrin, William Brian, Robert Van Horn and Fabrice HurbinDrug Metabolism and Disposition January 2012, 40 (1) 187-197; DOI: https://doi.org/10.1124/dmd.111.040394
I
Inoue, Tae
- You have accessSimultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and ActivitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Naoki Ishiguro, Wataru Kishimoto, Eva Ludwig-Schwellinger, Thomas Ebner and Tetsuya TerasakiDrug Metabolism and Disposition January 2012, 40 (1) 83-92; DOI: https://doi.org/10.1124/dmd.111.042259
- You have accessAbsolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human HepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Atsushi Sakamoto, Naoki Ishiguro, Takehisa Matsumaru, Tetsuya Terasaki and Thomas EbnerDrug Metabolism and Disposition January 2012, 40 (1) 93-103; DOI: https://doi.org/10.1124/dmd.111.042275
Ioannides, Costas
- You have accessDebrisoquine Metabolism and CYP2D Expression in Marmoset Liver MicrosomesBrian R. Cooke, S. W. Annie Bligh, Z. Richard Cybulski, Costas Ioannides and Michael HallDrug Metabolism and Disposition January 2012, 40 (1) 70-75; DOI: https://doi.org/10.1124/dmd.111.041566
Ishiguro, Naoki
- You have accessSimultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and ActivitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Naoki Ishiguro, Wataru Kishimoto, Eva Ludwig-Schwellinger, Thomas Ebner and Tetsuya TerasakiDrug Metabolism and Disposition January 2012, 40 (1) 83-92; DOI: https://doi.org/10.1124/dmd.111.042259
- You have accessAbsolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human HepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Atsushi Sakamoto, Naoki Ishiguro, Takehisa Matsumaru, Tetsuya Terasaki and Thomas EbnerDrug Metabolism and Disposition January 2012, 40 (1) 93-103; DOI: https://doi.org/10.1124/dmd.111.042275
Isoherranen, Nina
- You have accessPrediction of Relative In Vivo Metabolite Exposure from In Vitro Data Using Two Model Drugs: Dextromethorphan and OmeprazoleJustin D. Lutz and Nina IsoherranenDrug Metabolism and Disposition January 2012, 40 (1) 159-168; DOI: https://doi.org/10.1124/dmd.111.042200
Iyer, Ramaswamy A.
- You have accessIdentification of the Oxidative and Conjugative Enzymes Involved in the Biotransformation of BrivanibJiachang Gong, Jinping Gan and Ramaswamy A. IyerDrug Metabolism and Disposition January 2012, 40 (1) 219-226; DOI: https://doi.org/10.1124/dmd.111.042457
K
Kashikura, Kasumi
- You have accessAcetaminophen-Induced Hepatotoxicity in a Liver Tissue Model Consisting of Primary Hepatocytes Assembling around an Endothelial Cell NetworkYu Toyoda, Miho Tamai, Kasumi Kashikura, Shunsuke Kobayashi, Yoichi Fujiyama, Tomoyoshi Soga and Yoh-ichi TagawaDrug Metabolism and Disposition January 2012, 40 (1) 169-177; DOI: https://doi.org/10.1124/dmd.111.041137
Kawakami, Hirotaka
- You have accessSimultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and ActivitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Naoki Ishiguro, Wataru Kishimoto, Eva Ludwig-Schwellinger, Thomas Ebner and Tetsuya TerasakiDrug Metabolism and Disposition January 2012, 40 (1) 83-92; DOI: https://doi.org/10.1124/dmd.111.042259
- You have accessAbsolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human HepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Atsushi Sakamoto, Naoki Ishiguro, Takehisa Matsumaru, Tetsuya Terasaki and Thomas EbnerDrug Metabolism and Disposition January 2012, 40 (1) 93-103; DOI: https://doi.org/10.1124/dmd.111.042275
Kenna, J. Gerald
- You have accessIn Vitro Inhibition of the Bile Salt Export Pump Correlates with Risk of Cholestatic Drug-Induced Liver Injury in HumansSarah Dawson, Simone Stahl, Nikki Paul, Jane Barber and J. Gerald KennaDrug Metabolism and Disposition January 2012, 40 (1) 130-138; DOI: https://doi.org/10.1124/dmd.111.040758
Kishimoto, Wataru
- You have accessSimultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and ActivitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Naoki Ishiguro, Wataru Kishimoto, Eva Ludwig-Schwellinger, Thomas Ebner and Tetsuya TerasakiDrug Metabolism and Disposition January 2012, 40 (1) 83-92; DOI: https://doi.org/10.1124/dmd.111.042259
Knaak, James B.
- You have accessHuman Hepatic Cytochrome P450-Specific Metabolism of the Organophosphorus Pesticides Methyl Parathion and DiazinonCorie A. Ellison, Yuan Tian, James B. Knaak, Paul J. Kostyniak and James R. OlsonDrug Metabolism and Disposition January 2012, 40 (1) 1-5; DOI: https://doi.org/10.1124/dmd.111.042572
Kobayashi, Shunsuke
- You have accessAcetaminophen-Induced Hepatotoxicity in a Liver Tissue Model Consisting of Primary Hepatocytes Assembling around an Endothelial Cell NetworkYu Toyoda, Miho Tamai, Kasumi Kashikura, Shunsuke Kobayashi, Yoichi Fujiyama, Tomoyoshi Soga and Yoh-ichi TagawaDrug Metabolism and Disposition January 2012, 40 (1) 169-177; DOI: https://doi.org/10.1124/dmd.111.041137
Koch, Kevin
- You have accessHuman Metabolism of Lapatinib, a Dual Kinase Inhibitor: Implications for HepatotoxicityStephen Castellino, Michael O'Mara, Kevin Koch, David J. Borts, Gary D. Bowers and Christopher MacLauchlinDrug Metabolism and Disposition January 2012, 40 (1) 139-150; DOI: https://doi.org/10.1124/dmd.111.040949
Kostyniak, Paul J.
- You have accessHuman Hepatic Cytochrome P450-Specific Metabolism of the Organophosphorus Pesticides Methyl Parathion and DiazinonCorie A. Ellison, Yuan Tian, James B. Knaak, Paul J. Kostyniak and James R. OlsonDrug Metabolism and Disposition January 2012, 40 (1) 1-5; DOI: https://doi.org/10.1124/dmd.111.042572
Kwok, Hoi Hin
- You have accessCytoprotective Effect of 20(S)-Rg3 on Benzo[a]pyrene-Induced DNA DamagePo Ying Poon, Hoi Hin Kwok, Patrick Y. K. Yue, Mildred S. M. Yang, Nai Ki Mak, Chris K. C. Wong and Ricky N. S. WongDrug Metabolism and Disposition January 2012, 40 (1) 120-129; DOI: https://doi.org/10.1124/dmd.111.039503
L
Lambert, Carine
- You have accessInterindividual Variability in Gene Expression Profiles in Human Hepatocytes and Comparison with HepaRG CellsAlexandra Rogue, Carine Lambert, Catherine Spire, Nancy Claude and André GuillouzoDrug Metabolism and Disposition January 2012, 40 (1) 151-158; DOI: https://doi.org/10.1124/dmd.111.042028
Lau, Aik Jiang
- You have accessSpecies-Dependent and Receptor-Selective Action of Bilobalide on the Function of Constitutive Androstane Receptor and Pregnane X ReceptorAik Jiang Lau, Guixiang Yang, Ganesh Rajaraman, Christie C. Baucom and Thomas K. H. ChangDrug Metabolism and Disposition January 2012, 40 (1) 178-186; DOI: https://doi.org/10.1124/dmd.111.042879
Laurin, Louis-Philippe
- You have accessEffects of Chronic Renal Failure on Brain Drug Transporters in RatsJudith Naud, Louis-Philippe Laurin, Josée Michaud, Stéphanie Beauchemin, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition January 2012, 40 (1) 39-46; DOI: https://doi.org/10.1124/dmd.111.041145
Leblond, Francois A.
- You have accessEffects of Chronic Renal Failure on Brain Drug Transporters in RatsJudith Naud, Louis-Philippe Laurin, Josée Michaud, Stéphanie Beauchemin, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition January 2012, 40 (1) 39-46; DOI: https://doi.org/10.1124/dmd.111.041145
Li, Feng
- You have accessCPY3A4-Mediated Lopinavir Bioactivation and Its Inhibition by RitonavirFeng Li, Jie Lu and Xiaochao MaDrug Metabolism and Disposition January 2012, 40 (1) 18-24; DOI: https://doi.org/10.1124/dmd.111.041400
Liehner, Stephanie
- You have accessSimultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and ActivitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Naoki Ishiguro, Wataru Kishimoto, Eva Ludwig-Schwellinger, Thomas Ebner and Tetsuya TerasakiDrug Metabolism and Disposition January 2012, 40 (1) 83-92; DOI: https://doi.org/10.1124/dmd.111.042259
- You have accessAbsolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human HepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Atsushi Sakamoto, Naoki Ishiguro, Takehisa Matsumaru, Tetsuya Terasaki and Thomas EbnerDrug Metabolism and Disposition January 2012, 40 (1) 93-103; DOI: https://doi.org/10.1124/dmd.111.042275
Lu, Jie
- You have accessCPY3A4-Mediated Lopinavir Bioactivation and Its Inhibition by RitonavirFeng Li, Jie Lu and Xiaochao MaDrug Metabolism and Disposition January 2012, 40 (1) 18-24; DOI: https://doi.org/10.1124/dmd.111.041400
Ludwig-Schwellinger, Eva
- You have accessSimultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and ActivitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Naoki Ishiguro, Wataru Kishimoto, Eva Ludwig-Schwellinger, Thomas Ebner and Tetsuya TerasakiDrug Metabolism and Disposition January 2012, 40 (1) 83-92; DOI: https://doi.org/10.1124/dmd.111.042259
Lutz, Justin D.
- You have accessPrediction of Relative In Vivo Metabolite Exposure from In Vitro Data Using Two Model Drugs: Dextromethorphan and OmeprazoleJustin D. Lutz and Nina IsoherranenDrug Metabolism and Disposition January 2012, 40 (1) 159-168; DOI: https://doi.org/10.1124/dmd.111.042200
M
Ma, Xiaochao
- You have accessCPY3A4-Mediated Lopinavir Bioactivation and Its Inhibition by RitonavirFeng Li, Jie Lu and Xiaochao MaDrug Metabolism and Disposition January 2012, 40 (1) 18-24; DOI: https://doi.org/10.1124/dmd.111.041400
MacLauchlin, Christopher
- You have accessHuman Metabolism of Lapatinib, a Dual Kinase Inhibitor: Implications for HepatotoxicityStephen Castellino, Michael O'Mara, Kevin Koch, David J. Borts, Gary D. Bowers and Christopher MacLauchlinDrug Metabolism and Disposition January 2012, 40 (1) 139-150; DOI: https://doi.org/10.1124/dmd.111.040949
Mak, Nai Ki
- You have accessCytoprotective Effect of 20(S)-Rg3 on Benzo[a]pyrene-Induced DNA DamagePo Ying Poon, Hoi Hin Kwok, Patrick Y. K. Yue, Mildred S. M. Yang, Nai Ki Mak, Chris K. C. Wong and Ricky N. S. WongDrug Metabolism and Disposition January 2012, 40 (1) 120-129; DOI: https://doi.org/10.1124/dmd.111.039503
Makar, Karen W.
- You have accessPotential Contribution of Cytochrome P450 2B6 to Hepatic 4-Hydroxycyclophosphamide Formation In Vitro and In VivoBrianne S. Raccor, Adam J. Claessens, Jean C. Dinh, Julie R. Park, Douglas S. Hawkins, Sushma S. Thomas, Karen W. Makar, Jeannine S. McCune and Rheem A. TotahDrug Metabolism and Disposition January 2012, 40 (1) 54-63; DOI: https://doi.org/10.1124/dmd.111.039347
Martin, Hélène
- You have accessBupropion Hydroxylation as a Selective Marker of Rat CYP2B1 Catalytic ActivityDumrongsak Pekthong, Coraline Desbans, Hélène Martin and Lysiane RichertDrug Metabolism and Disposition January 2012, 40 (1) 32-38; DOI: https://doi.org/10.1124/dmd.111.041368
Matsumaru, Takehisa
- You have accessAbsolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human HepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Atsushi Sakamoto, Naoki Ishiguro, Takehisa Matsumaru, Tetsuya Terasaki and Thomas EbnerDrug Metabolism and Disposition January 2012, 40 (1) 93-103; DOI: https://doi.org/10.1124/dmd.111.042275
Maul, R.
- You have accessIn Vitro Glucuronidation of the Antibacterial Triclocarban and Its Oxidative MetabolitesN. H. Schebb, B. Franze, R. Maul, A. Ranganathan and B. D. HammockDrug Metabolism and Disposition January 2012, 40 (1) 25-31; DOI: https://doi.org/10.1124/dmd.111.042283
McCune, Jeannine S.
- You have accessPotential Contribution of Cytochrome P450 2B6 to Hepatic 4-Hydroxycyclophosphamide Formation In Vitro and In VivoBrianne S. Raccor, Adam J. Claessens, Jean C. Dinh, Julie R. Park, Douglas S. Hawkins, Sushma S. Thomas, Karen W. Makar, Jeannine S. McCune and Rheem A. TotahDrug Metabolism and Disposition January 2012, 40 (1) 54-63; DOI: https://doi.org/10.1124/dmd.111.039347
Michaud, Josée
- You have accessEffects of Chronic Renal Failure on Brain Drug Transporters in RatsJudith Naud, Louis-Philippe Laurin, Josée Michaud, Stéphanie Beauchemin, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition January 2012, 40 (1) 39-46; DOI: https://doi.org/10.1124/dmd.111.041145
Millner, Lori M.
- You have accessPhenotype of the Most Common “Slow Acetylator” Arylamine N-Acetyltransferase 1 Genetic Variant (NAT1*14B) Is Substrate-DependentLori M. Millner, Mark A. Doll, Jian Cai, J. Christopher States and David W. HeinDrug Metabolism and Disposition January 2012, 40 (1) 198-204; DOI: https://doi.org/10.1124/dmd.111.041855
Morris, Marilyn E.
- You have accessγ-Hydroxybutyrate Blood/Plasma Partitioning: Effect of Physiologic pH on Transport by Monocarboxylate TransportersBridget L. Morse, Melanie A. Felmlee and Marilyn E. MorrisDrug Metabolism and Disposition January 2012, 40 (1) 64-69; DOI: https://doi.org/10.1124/dmd.111.041285
- You have accessBrain Uptake of the Drug of Abuse γ-Hydroxybutyric Acid in RatsSamuel A. Roiko, Melanie A. Felmlee and Marilyn E. MorrisDrug Metabolism and Disposition January 2012, 40 (1) 212-218; DOI: https://doi.org/10.1124/dmd.111.041749
Morse, Bridget L.
- You have accessγ-Hydroxybutyrate Blood/Plasma Partitioning: Effect of Physiologic pH on Transport by Monocarboxylate TransportersBridget L. Morse, Melanie A. Felmlee and Marilyn E. MorrisDrug Metabolism and Disposition January 2012, 40 (1) 64-69; DOI: https://doi.org/10.1124/dmd.111.041285
Murai, Hidetsugu
- You have accessPrediction of Human Metabolism of FK3453 by Aldehyde Oxidase Using Chimeric Mice Transplanted with Human or Rat HepatocytesSeigo Sanoh, Kazuyoshi Nozaki, Hidetsugu Murai, Shigeyuki Terashita, Toshio Teramura and Shigeru OhtaDrug Metabolism and Disposition January 2012, 40 (1) 76-82; DOI: https://doi.org/10.1124/dmd.111.041954
N
Naud, Judith
- You have accessEffects of Chronic Renal Failure on Brain Drug Transporters in RatsJudith Naud, Louis-Philippe Laurin, Josée Michaud, Stéphanie Beauchemin, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition January 2012, 40 (1) 39-46; DOI: https://doi.org/10.1124/dmd.111.041145
Nozaki, Kazuyoshi
- You have accessPrediction of Human Metabolism of FK3453 by Aldehyde Oxidase Using Chimeric Mice Transplanted with Human or Rat HepatocytesSeigo Sanoh, Kazuyoshi Nozaki, Hidetsugu Murai, Shigeyuki Terashita, Toshio Teramura and Shigeru OhtaDrug Metabolism and Disposition January 2012, 40 (1) 76-82; DOI: https://doi.org/10.1124/dmd.111.041954
O
O'Kane, Dennis J.
- You have accessFrequency of Undetected CYP2D6 Hybrid Genes in Clinical Samples: Impact on Phenotype PredictionJohn Logan Black, Denise L. Walker, Dennis J. O'Kane and Maria HarmandayanDrug Metabolism and Disposition January 2012, 40 (1) 111-119; DOI: https://doi.org/10.1124/dmd.111.040832
O'Mara, Michael
- You have accessHuman Metabolism of Lapatinib, a Dual Kinase Inhibitor: Implications for HepatotoxicityStephen Castellino, Michael O'Mara, Kevin Koch, David J. Borts, Gary D. Bowers and Christopher MacLauchlinDrug Metabolism and Disposition January 2012, 40 (1) 139-150; DOI: https://doi.org/10.1124/dmd.111.040949
Ohta, Shigeru
- You have accessPrediction of Human Metabolism of FK3453 by Aldehyde Oxidase Using Chimeric Mice Transplanted with Human or Rat HepatocytesSeigo Sanoh, Kazuyoshi Nozaki, Hidetsugu Murai, Shigeyuki Terashita, Toshio Teramura and Shigeru OhtaDrug Metabolism and Disposition January 2012, 40 (1) 76-82; DOI: https://doi.org/10.1124/dmd.111.041954
Ohtsuki, Sumio
- You have accessSimultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and ActivitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Naoki Ishiguro, Wataru Kishimoto, Eva Ludwig-Schwellinger, Thomas Ebner and Tetsuya TerasakiDrug Metabolism and Disposition January 2012, 40 (1) 83-92; DOI: https://doi.org/10.1124/dmd.111.042259
- You have accessAbsolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human HepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Atsushi Sakamoto, Naoki Ishiguro, Takehisa Matsumaru, Tetsuya Terasaki and Thomas EbnerDrug Metabolism and Disposition January 2012, 40 (1) 93-103; DOI: https://doi.org/10.1124/dmd.111.042275
Olson, Carol A.
- You have accessA Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite PairGrace Zhixia Yan, Claudia N. Generaux, Miyoung Yoon, Rachel B. Goldsmith, Richard R. Tidwell, James E. Hall, Carol A. Olson, Harvey J. Clewell, Kim L. R. Brouwer and Mary F. PaineDrug Metabolism and Disposition January 2012, 40 (1) 6-17; DOI: https://doi.org/10.1124/dmd.111.040063
Olson, James R.
- You have accessHuman Hepatic Cytochrome P450-Specific Metabolism of the Organophosphorus Pesticides Methyl Parathion and DiazinonCorie A. Ellison, Yuan Tian, James B. Knaak, Paul J. Kostyniak and James R. OlsonDrug Metabolism and Disposition January 2012, 40 (1) 1-5; DOI: https://doi.org/10.1124/dmd.111.042572
P
Paine, Mary F.
- You have accessA Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite PairGrace Zhixia Yan, Claudia N. Generaux, Miyoung Yoon, Rachel B. Goldsmith, Richard R. Tidwell, James E. Hall, Carol A. Olson, Harvey J. Clewell, Kim L. R. Brouwer and Mary F. PaineDrug Metabolism and Disposition January 2012, 40 (1) 6-17; DOI: https://doi.org/10.1124/dmd.111.040063
Park, Julie R.
- You have accessPotential Contribution of Cytochrome P450 2B6 to Hepatic 4-Hydroxycyclophosphamide Formation In Vitro and In VivoBrianne S. Raccor, Adam J. Claessens, Jean C. Dinh, Julie R. Park, Douglas S. Hawkins, Sushma S. Thomas, Karen W. Makar, Jeannine S. McCune and Rheem A. TotahDrug Metabolism and Disposition January 2012, 40 (1) 54-63; DOI: https://doi.org/10.1124/dmd.111.039347
Paul, Nikki
- You have accessIn Vitro Inhibition of the Bile Salt Export Pump Correlates with Risk of Cholestatic Drug-Induced Liver Injury in HumansSarah Dawson, Simone Stahl, Nikki Paul, Jane Barber and J. Gerald KennaDrug Metabolism and Disposition January 2012, 40 (1) 130-138; DOI: https://doi.org/10.1124/dmd.111.040758
Pekthong, Dumrongsak
- You have accessBupropion Hydroxylation as a Selective Marker of Rat CYP2B1 Catalytic ActivityDumrongsak Pekthong, Coraline Desbans, Hélène Martin and Lysiane RichertDrug Metabolism and Disposition January 2012, 40 (1) 32-38; DOI: https://doi.org/10.1124/dmd.111.041368
Perrin, Laurent
- You have accessEffects of Omeprazole and Genetic Polymorphism of CYP2C19 on the Clopidogrel Active MetaboliteXavier Boulenc, Nassim Djebli, Juan Shi, Laurent Perrin, William Brian, Robert Van Horn and Fabrice HurbinDrug Metabolism and Disposition January 2012, 40 (1) 187-197; DOI: https://doi.org/10.1124/dmd.111.040394
Pichette, Vincent
- You have accessEffects of Chronic Renal Failure on Brain Drug Transporters in RatsJudith Naud, Louis-Philippe Laurin, Josée Michaud, Stéphanie Beauchemin, Francois A. Leblond and Vincent PichetteDrug Metabolism and Disposition January 2012, 40 (1) 39-46; DOI: https://doi.org/10.1124/dmd.111.041145
Poon, Po Ying
- You have accessCytoprotective Effect of 20(S)-Rg3 on Benzo[a]pyrene-Induced DNA DamagePo Ying Poon, Hoi Hin Kwok, Patrick Y. K. Yue, Mildred S. M. Yang, Nai Ki Mak, Chris K. C. Wong and Ricky N. S. WongDrug Metabolism and Disposition January 2012, 40 (1) 120-129; DOI: https://doi.org/10.1124/dmd.111.039503
R
Raccor, Brianne S.
- You have accessPotential Contribution of Cytochrome P450 2B6 to Hepatic 4-Hydroxycyclophosphamide Formation In Vitro and In VivoBrianne S. Raccor, Adam J. Claessens, Jean C. Dinh, Julie R. Park, Douglas S. Hawkins, Sushma S. Thomas, Karen W. Makar, Jeannine S. McCune and Rheem A. TotahDrug Metabolism and Disposition January 2012, 40 (1) 54-63; DOI: https://doi.org/10.1124/dmd.111.039347
Rajaraman, Ganesh
- You have accessSpecies-Dependent and Receptor-Selective Action of Bilobalide on the Function of Constitutive Androstane Receptor and Pregnane X ReceptorAik Jiang Lau, Guixiang Yang, Ganesh Rajaraman, Christie C. Baucom and Thomas K. H. ChangDrug Metabolism and Disposition January 2012, 40 (1) 178-186; DOI: https://doi.org/10.1124/dmd.111.042879
Ranganathan, A.
- You have accessIn Vitro Glucuronidation of the Antibacterial Triclocarban and Its Oxidative MetabolitesN. H. Schebb, B. Franze, R. Maul, A. Ranganathan and B. D. HammockDrug Metabolism and Disposition January 2012, 40 (1) 25-31; DOI: https://doi.org/10.1124/dmd.111.042283
Richert, Lysiane
- You have accessBupropion Hydroxylation as a Selective Marker of Rat CYP2B1 Catalytic ActivityDumrongsak Pekthong, Coraline Desbans, Hélène Martin and Lysiane RichertDrug Metabolism and Disposition January 2012, 40 (1) 32-38; DOI: https://doi.org/10.1124/dmd.111.041368
Rock, Dan A.
- You have accessPrediction of CYP2D6 Drug Interactions from In Vitro Data: Evidence for Substrate-Dependent InhibitionBrooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. WahlstromDrug Metabolism and Disposition January 2012, 40 (1) 47-53; DOI: https://doi.org/10.1124/dmd.111.041210
Rogue, Alexandra
- You have accessInterindividual Variability in Gene Expression Profiles in Human Hepatocytes and Comparison with HepaRG CellsAlexandra Rogue, Carine Lambert, Catherine Spire, Nancy Claude and André GuillouzoDrug Metabolism and Disposition January 2012, 40 (1) 151-158; DOI: https://doi.org/10.1124/dmd.111.042028
Roiko, Samuel A.
- You have accessBrain Uptake of the Drug of Abuse γ-Hydroxybutyric Acid in RatsSamuel A. Roiko, Melanie A. Felmlee and Marilyn E. MorrisDrug Metabolism and Disposition January 2012, 40 (1) 212-218; DOI: https://doi.org/10.1124/dmd.111.041749
S
Saito, Asami
- You have accessSimultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and ActivitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Naoki Ishiguro, Wataru Kishimoto, Eva Ludwig-Schwellinger, Thomas Ebner and Tetsuya TerasakiDrug Metabolism and Disposition January 2012, 40 (1) 83-92; DOI: https://doi.org/10.1124/dmd.111.042259
- You have accessAbsolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human HepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Atsushi Sakamoto, Naoki Ishiguro, Takehisa Matsumaru, Tetsuya Terasaki and Thomas EbnerDrug Metabolism and Disposition January 2012, 40 (1) 93-103; DOI: https://doi.org/10.1124/dmd.111.042275
Sakamoto, Atsushi
- You have accessAbsolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human HepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Atsushi Sakamoto, Naoki Ishiguro, Takehisa Matsumaru, Tetsuya Terasaki and Thomas EbnerDrug Metabolism and Disposition January 2012, 40 (1) 93-103; DOI: https://doi.org/10.1124/dmd.111.042275
Sanoh, Seigo
- You have accessPrediction of Human Metabolism of FK3453 by Aldehyde Oxidase Using Chimeric Mice Transplanted with Human or Rat HepatocytesSeigo Sanoh, Kazuyoshi Nozaki, Hidetsugu Murai, Shigeyuki Terashita, Toshio Teramura and Shigeru OhtaDrug Metabolism and Disposition January 2012, 40 (1) 76-82; DOI: https://doi.org/10.1124/dmd.111.041954
Schaefer, Olaf
- You have accessSimultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and ActivitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Naoki Ishiguro, Wataru Kishimoto, Eva Ludwig-Schwellinger, Thomas Ebner and Tetsuya TerasakiDrug Metabolism and Disposition January 2012, 40 (1) 83-92; DOI: https://doi.org/10.1124/dmd.111.042259
- You have accessAbsolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human HepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Atsushi Sakamoto, Naoki Ishiguro, Takehisa Matsumaru, Tetsuya Terasaki and Thomas EbnerDrug Metabolism and Disposition January 2012, 40 (1) 93-103; DOI: https://doi.org/10.1124/dmd.111.042275
Schebb, N. H.
- You have accessIn Vitro Glucuronidation of the Antibacterial Triclocarban and Its Oxidative MetabolitesN. H. Schebb, B. Franze, R. Maul, A. Ranganathan and B. D. HammockDrug Metabolism and Disposition January 2012, 40 (1) 25-31; DOI: https://doi.org/10.1124/dmd.111.042283
Shi, Juan
- You have accessEffects of Omeprazole and Genetic Polymorphism of CYP2C19 on the Clopidogrel Active MetaboliteXavier Boulenc, Nassim Djebli, Juan Shi, Laurent Perrin, William Brian, Robert Van Horn and Fabrice HurbinDrug Metabolism and Disposition January 2012, 40 (1) 187-197; DOI: https://doi.org/10.1124/dmd.111.040394
Soga, Tomoyoshi
- You have accessAcetaminophen-Induced Hepatotoxicity in a Liver Tissue Model Consisting of Primary Hepatocytes Assembling around an Endothelial Cell NetworkYu Toyoda, Miho Tamai, Kasumi Kashikura, Shunsuke Kobayashi, Yoichi Fujiyama, Tomoyoshi Soga and Yoh-ichi TagawaDrug Metabolism and Disposition January 2012, 40 (1) 169-177; DOI: https://doi.org/10.1124/dmd.111.041137
Spire, Catherine
- You have accessInterindividual Variability in Gene Expression Profiles in Human Hepatocytes and Comparison with HepaRG CellsAlexandra Rogue, Carine Lambert, Catherine Spire, Nancy Claude and André GuillouzoDrug Metabolism and Disposition January 2012, 40 (1) 151-158; DOI: https://doi.org/10.1124/dmd.111.042028
Stahl, Simone
- You have accessIn Vitro Inhibition of the Bile Salt Export Pump Correlates with Risk of Cholestatic Drug-Induced Liver Injury in HumansSarah Dawson, Simone Stahl, Nikki Paul, Jane Barber and J. Gerald KennaDrug Metabolism and Disposition January 2012, 40 (1) 130-138; DOI: https://doi.org/10.1124/dmd.111.040758
States, J. Christopher
- You have accessPhenotype of the Most Common “Slow Acetylator” Arylamine N-Acetyltransferase 1 Genetic Variant (NAT1*14B) Is Substrate-DependentLori M. Millner, Mark A. Doll, Jian Cai, J. Christopher States and David W. HeinDrug Metabolism and Disposition January 2012, 40 (1) 198-204; DOI: https://doi.org/10.1124/dmd.111.041855
Strobel, Henry W.
- You have accessRegulation of Cytochrome P450 4F11 by Nuclear Transcription Factor-κBJordan C. Bell and Henry W. StrobelDrug Metabolism and Disposition January 2012, 40 (1) 205-211; DOI: https://doi.org/10.1124/dmd.111.041178
T
Tagawa, Yoh-ichi
- You have accessAcetaminophen-Induced Hepatotoxicity in a Liver Tissue Model Consisting of Primary Hepatocytes Assembling around an Endothelial Cell NetworkYu Toyoda, Miho Tamai, Kasumi Kashikura, Shunsuke Kobayashi, Yoichi Fujiyama, Tomoyoshi Soga and Yoh-ichi TagawaDrug Metabolism and Disposition January 2012, 40 (1) 169-177; DOI: https://doi.org/10.1124/dmd.111.041137
Tamai, Miho
- You have accessAcetaminophen-Induced Hepatotoxicity in a Liver Tissue Model Consisting of Primary Hepatocytes Assembling around an Endothelial Cell NetworkYu Toyoda, Miho Tamai, Kasumi Kashikura, Shunsuke Kobayashi, Yoichi Fujiyama, Tomoyoshi Soga and Yoh-ichi TagawaDrug Metabolism and Disposition January 2012, 40 (1) 169-177; DOI: https://doi.org/10.1124/dmd.111.041137
Teramura, Toshio
- You have accessPrediction of Human Metabolism of FK3453 by Aldehyde Oxidase Using Chimeric Mice Transplanted with Human or Rat HepatocytesSeigo Sanoh, Kazuyoshi Nozaki, Hidetsugu Murai, Shigeyuki Terashita, Toshio Teramura and Shigeru OhtaDrug Metabolism and Disposition January 2012, 40 (1) 76-82; DOI: https://doi.org/10.1124/dmd.111.041954
Terasaki, Tetsuya
- You have accessSimultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and ActivitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Naoki Ishiguro, Wataru Kishimoto, Eva Ludwig-Schwellinger, Thomas Ebner and Tetsuya TerasakiDrug Metabolism and Disposition January 2012, 40 (1) 83-92; DOI: https://doi.org/10.1124/dmd.111.042259
- You have accessAbsolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human HepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Stephanie Liehner, Asami Saito, Atsushi Sakamoto, Naoki Ishiguro, Takehisa Matsumaru, Tetsuya Terasaki and Thomas EbnerDrug Metabolism and Disposition January 2012, 40 (1) 93-103; DOI: https://doi.org/10.1124/dmd.111.042275
Terashita, Shigeyuki
- You have accessPrediction of Human Metabolism of FK3453 by Aldehyde Oxidase Using Chimeric Mice Transplanted with Human or Rat HepatocytesSeigo Sanoh, Kazuyoshi Nozaki, Hidetsugu Murai, Shigeyuki Terashita, Toshio Teramura and Shigeru OhtaDrug Metabolism and Disposition January 2012, 40 (1) 76-82; DOI: https://doi.org/10.1124/dmd.111.041954
Thomas, Sushma S.
- You have accessPotential Contribution of Cytochrome P450 2B6 to Hepatic 4-Hydroxycyclophosphamide Formation In Vitro and In VivoBrianne S. Raccor, Adam J. Claessens, Jean C. Dinh, Julie R. Park, Douglas S. Hawkins, Sushma S. Thomas, Karen W. Makar, Jeannine S. McCune and Rheem A. TotahDrug Metabolism and Disposition January 2012, 40 (1) 54-63; DOI: https://doi.org/10.1124/dmd.111.039347
Tian, Yuan
- You have accessHuman Hepatic Cytochrome P450-Specific Metabolism of the Organophosphorus Pesticides Methyl Parathion and DiazinonCorie A. Ellison, Yuan Tian, James B. Knaak, Paul J. Kostyniak and James R. OlsonDrug Metabolism and Disposition January 2012, 40 (1) 1-5; DOI: https://doi.org/10.1124/dmd.111.042572
Tidwell, Richard R.
- You have accessA Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite PairGrace Zhixia Yan, Claudia N. Generaux, Miyoung Yoon, Rachel B. Goldsmith, Richard R. Tidwell, James E. Hall, Carol A. Olson, Harvey J. Clewell, Kim L. R. Brouwer and Mary F. PaineDrug Metabolism and Disposition January 2012, 40 (1) 6-17; DOI: https://doi.org/10.1124/dmd.111.040063
Totah, Rheem A.
- You have accessPotential Contribution of Cytochrome P450 2B6 to Hepatic 4-Hydroxycyclophosphamide Formation In Vitro and In VivoBrianne S. Raccor, Adam J. Claessens, Jean C. Dinh, Julie R. Park, Douglas S. Hawkins, Sushma S. Thomas, Karen W. Makar, Jeannine S. McCune and Rheem A. TotahDrug Metabolism and Disposition January 2012, 40 (1) 54-63; DOI: https://doi.org/10.1124/dmd.111.039347
Toyoda, Yu
- You have accessAcetaminophen-Induced Hepatotoxicity in a Liver Tissue Model Consisting of Primary Hepatocytes Assembling around an Endothelial Cell NetworkYu Toyoda, Miho Tamai, Kasumi Kashikura, Shunsuke Kobayashi, Yoichi Fujiyama, Tomoyoshi Soga and Yoh-ichi TagawaDrug Metabolism and Disposition January 2012, 40 (1) 169-177; DOI: https://doi.org/10.1124/dmd.111.041137
Turlizzi, Elisa
- You have accessComparison of Cryopreserved HepaRG Cells with Cryopreserved Human Hepatocytes for Prediction of Clearance for 26 DrugsUgo Zanelli, Nicola Pasquale Caradonna, David Hallifax, Elisa Turlizzi and J. Brian HoustonDrug Metabolism and Disposition January 2012, 40 (1) 104-110; DOI: https://doi.org/10.1124/dmd.111.042309
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VandenBrink, Brooke M.
- You have accessPrediction of CYP2D6 Drug Interactions from In Vitro Data: Evidence for Substrate-Dependent InhibitionBrooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. WahlstromDrug Metabolism and Disposition January 2012, 40 (1) 47-53; DOI: https://doi.org/10.1124/dmd.111.041210
Van Horn, Robert
- You have accessEffects of Omeprazole and Genetic Polymorphism of CYP2C19 on the Clopidogrel Active MetaboliteXavier Boulenc, Nassim Djebli, Juan Shi, Laurent Perrin, William Brian, Robert Van Horn and Fabrice HurbinDrug Metabolism and Disposition January 2012, 40 (1) 187-197; DOI: https://doi.org/10.1124/dmd.111.040394
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Wahlstrom, Jan L.
- You have accessPrediction of CYP2D6 Drug Interactions from In Vitro Data: Evidence for Substrate-Dependent InhibitionBrooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. WahlstromDrug Metabolism and Disposition January 2012, 40 (1) 47-53; DOI: https://doi.org/10.1124/dmd.111.041210
Walker, Denise L.
- You have accessFrequency of Undetected CYP2D6 Hybrid Genes in Clinical Samples: Impact on Phenotype PredictionJohn Logan Black, Denise L. Walker, Dennis J. O'Kane and Maria HarmandayanDrug Metabolism and Disposition January 2012, 40 (1) 111-119; DOI: https://doi.org/10.1124/dmd.111.040832
Wienkers, Larry C.
- You have accessPrediction of CYP2D6 Drug Interactions from In Vitro Data: Evidence for Substrate-Dependent InhibitionBrooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers and Jan L. WahlstromDrug Metabolism and Disposition January 2012, 40 (1) 47-53; DOI: https://doi.org/10.1124/dmd.111.041210
Wong, Chris K. C.
- You have accessCytoprotective Effect of 20(S)-Rg3 on Benzo[a]pyrene-Induced DNA DamagePo Ying Poon, Hoi Hin Kwok, Patrick Y. K. Yue, Mildred S. M. Yang, Nai Ki Mak, Chris K. C. Wong and Ricky N. S. WongDrug Metabolism and Disposition January 2012, 40 (1) 120-129; DOI: https://doi.org/10.1124/dmd.111.039503
Wong, Ricky N. S.
- You have accessCytoprotective Effect of 20(S)-Rg3 on Benzo[a]pyrene-Induced DNA DamagePo Ying Poon, Hoi Hin Kwok, Patrick Y. K. Yue, Mildred S. M. Yang, Nai Ki Mak, Chris K. C. Wong and Ricky N. S. WongDrug Metabolism and Disposition January 2012, 40 (1) 120-129; DOI: https://doi.org/10.1124/dmd.111.039503
Y
Yan, Grace Zhixia
- You have accessA Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite PairGrace Zhixia Yan, Claudia N. Generaux, Miyoung Yoon, Rachel B. Goldsmith, Richard R. Tidwell, James E. Hall, Carol A. Olson, Harvey J. Clewell, Kim L. R. Brouwer and Mary F. PaineDrug Metabolism and Disposition January 2012, 40 (1) 6-17; DOI: https://doi.org/10.1124/dmd.111.040063
Yang, Guixiang
- You have accessSpecies-Dependent and Receptor-Selective Action of Bilobalide on the Function of Constitutive Androstane Receptor and Pregnane X ReceptorAik Jiang Lau, Guixiang Yang, Ganesh Rajaraman, Christie C. Baucom and Thomas K. H. ChangDrug Metabolism and Disposition January 2012, 40 (1) 178-186; DOI: https://doi.org/10.1124/dmd.111.042879
Yang, Mildred S. M.
- You have accessCytoprotective Effect of 20(S)-Rg3 on Benzo[a]pyrene-Induced DNA DamagePo Ying Poon, Hoi Hin Kwok, Patrick Y. K. Yue, Mildred S. M. Yang, Nai Ki Mak, Chris K. C. Wong and Ricky N. S. WongDrug Metabolism and Disposition January 2012, 40 (1) 120-129; DOI: https://doi.org/10.1124/dmd.111.039503
Yoon, Miyoung
- You have accessA Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite PairGrace Zhixia Yan, Claudia N. Generaux, Miyoung Yoon, Rachel B. Goldsmith, Richard R. Tidwell, James E. Hall, Carol A. Olson, Harvey J. Clewell, Kim L. R. Brouwer and Mary F. PaineDrug Metabolism and Disposition January 2012, 40 (1) 6-17; DOI: https://doi.org/10.1124/dmd.111.040063
Yue, Patrick Y. K.
- You have accessCytoprotective Effect of 20(S)-Rg3 on Benzo[a]pyrene-Induced DNA DamagePo Ying Poon, Hoi Hin Kwok, Patrick Y. K. Yue, Mildred S. M. Yang, Nai Ki Mak, Chris K. C. Wong and Ricky N. S. WongDrug Metabolism and Disposition January 2012, 40 (1) 120-129; DOI: https://doi.org/10.1124/dmd.111.039503
Z
Zanelli, Ugo
- You have accessComparison of Cryopreserved HepaRG Cells with Cryopreserved Human Hepatocytes for Prediction of Clearance for 26 DrugsUgo Zanelli, Nicola Pasquale Caradonna, David Hallifax, Elisa Turlizzi and J. Brian HoustonDrug Metabolism and Disposition January 2012, 40 (1) 104-110; DOI: https://doi.org/10.1124/dmd.111.042309
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