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Research ArticleArticle

Comparison of Cryopreserved HepaRG Cells with Cryopreserved Human Hepatocytes for Prediction of Clearance for 26 Drugs

Ugo Zanelli, Nicola Pasquale Caradonna, David Hallifax, Elisa Turlizzi and J. Brian Houston
Drug Metabolism and Disposition January 2012, 40 (1) 104-110; DOI: https://doi.org/10.1124/dmd.111.042309

Article Information

vol. 40 no. 1 104-110
DOI 
https://doi.org/10.1124/dmd.111.042309
PubMed 
21998403
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 16, 2011
  • Accepted October 13, 2011
  • Published online December 16, 2011.

Article Versions

Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Ugo Zanelli,
  2. Nicola Pasquale Caradonna,
  3. David Hallifax,
  4. Elisa Turlizzi and
  5. J. Brian Houston
  1. Metabolic Profiling, Screening and Technologies Department, Siena Biotech S.p.A., Siena, Italy (U.Z., N.P.C., E.T.); and Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, United Kingdom (D.H., J.B.H.)
  1. Address correspondence to:
    Dr. David Hallifax, Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester M13 9PL, UK. E-mail: david.hallifax{at}manchester.ac.uk
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CLint IN CRYOPRESERVED HepaRG CELLS AND HEPATOCYTES

Ugo Zanelli, Nicola Pasquale Caradonna, David Hallifax, Elisa Turlizzi and J. Brian Houston
Drug Metabolism and Disposition January 1, 2012, 40 (1) 104-110; DOI: https://doi.org/10.1124/dmd.111.042309
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