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Index by author

October 01, 2012; Volume 40,Issue 10

A

  1. Abo, Ryan P.

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  2. Anderson, Amy C.

    1. Acetylenic Linkers in Lead Compounds: A Study of the Stability of the Propargyl-Linked Antifolates
      Wangda Zhou, Kishore Viswanathan, Dennis Hill, Amy C. Anderson and Dennis L. Wright
      Drug Metabolism and Disposition October 2012, 40 (10) 2002-2008; DOI: https://doi.org/10.1124/dmd.112.046870

  3. Annes, William F.

    1. The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
      Mosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. Hall
      Drug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060

  4. Ayan-Oshodi, Mosun A.

    1. The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
      Mosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. Hall
      Drug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060

B

  1. Barbara, Joanna E.

    1. High-Resolution Mass Spectrometry Elucidates Metabonate (False Metabolite) Formation from Alkylamine Drugs during In Vitro Metabolite Profiling
      Joanna E. Barbara, Faraz Kazmi, Seema Muranjan, Paul C. Toren and Andrew Parkinson
      Drug Metabolism and Disposition October 2012, 40 (10) 1966-1975; DOI: https://doi.org/10.1124/dmd.112.047027

  2. Boado, Ruben J.

    1. Glycemic Control and Chronic Dosing of Rhesus Monkeys with a Fusion Protein of Iduronidase and a Monoclonal Antibody Against the Human Insulin Receptor
      Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition October 2012, 40 (10) 2021-2025; DOI: https://doi.org/10.1124/dmd.112.046375

  3. Boysen, Gunnar

    1. CYP2E1 Metabolism of Styrene Involves Allostery
      Jessica H. Hartman, Gunnar Boysen and Grover P. Miller
      Drug Metabolism and Disposition October 2012, 40 (10) 1976-1983; DOI: https://doi.org/10.1124/dmd.112.046698

  4. Broly, Franck

    1. Xenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression Profiles
      Elisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-Guidice
      Drug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896

  5. Brown, Thomas

    1. The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
      Mosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. Hall
      Drug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060

  6. Burian, Angela

    1. Absolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy Subjects
      Guus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham Lappin
      Drug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623

C

  1. Canney, Daniel J.

    1. In Vivo-Formed versus Preformed Metabolite Kinetics of trans-Resveratrol-3-sulfate and trans-Resveratrol-3-glucuronide
      Satish Sharan, Otito F. Iwuchukwu, Daniel J. Canney, Cheryl L. Zimmerman and Swati Nagar
      Drug Metabolism and Disposition October 2012, 40 (10) 1993-2001; DOI: https://doi.org/10.1124/dmd.112.046417

  2. Chai, Xiaoshan

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  3. Chai, Yubo

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  4. Chen, Xiaoyan

    1. In Vitro Studies on the Oxidative Metabolism of 20(S)-Ginsenoside Rh2 in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes, and Human Liver S9
      Liang Li, Xiaoyan Chen, Jialan Zhou and Dafang Zhong
      Drug Metabolism and Disposition October 2012, 40 (10) 2041-2053; DOI: https://doi.org/10.1124/dmd.112.046995
    2. Mechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic Characteristics
      Chunying Gao, Hongjian Zhang, Zitao Guo, Tiangeng You, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2012, 40 (10) 2009-2020; DOI: https://doi.org/10.1124/dmd.112.047183

  5. Chow, Edwin C. Y.

    1. Commentary: Theoretical Predictions of Flow Effects on Intestinal and Systemic Availability in Physiologically Based Pharmacokinetic Intestine Models: The Traditional Model, Segregated Flow Model, and QGut Model
      K. Sandy Pang and Edwin C. Y. Chow
      Drug Metabolism and Disposition October 2012, 40 (10) 1869-1877; DOI: https://doi.org/10.1124/dmd.112.045872

  6. Cochrane, Brett

    1. Absolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy Subjects
      Guus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham Lappin
      Drug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623

  7. Courcot, Elisabeth

    1. Xenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression Profiles
      Elisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-Guidice
      Drug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896

  8. Cremers, Thomas I. F. H.

    1. Microdialysis Evaluation of Clozapine and N-Desmethylclozapine Pharmacokinetics in Rat Brain
      Thomas I. F. H. Cremers, Gunnar Flik, Corry Hofland and Robert E. Stratford
      Drug Metabolism and Disposition October 2012, 40 (10) 1909-1916; DOI: https://doi.org/10.1124/dmd.112.045682

D

  1. Davis, John A.

    1. In Vitro Characterization of the Drug-Drug Interaction Potential of Catabolites of Antibody-Maytansinoid Conjugates
      John A. Davis, Dan A. Rock, Larry C. Wienkers and Josh T. Pearson
      Drug Metabolism and Disposition October 2012, 40 (10) 1927-1934; DOI: https://doi.org/10.1124/dmd.112.046169

  2. de la Peña, Amparo

    1. The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
      Mosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. Hall
      Drug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060

  3. Duchateau, Guus

    1. Absolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy Subjects
      Guus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham Lappin
      Drug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623

E

  1. Eckloff, Bruce W.

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

F

  1. Finel, Moshe

    1. Human UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation Kinetics
      Hongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe Finel
      Drug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086

  2. Flik, Gunnar

    1. Microdialysis Evaluation of Clozapine and N-Desmethylclozapine Pharmacokinetics in Rat Brain
      Thomas I. F. H. Cremers, Gunnar Flik, Corry Hofland and Robert E. Stratford
      Drug Metabolism and Disposition October 2012, 40 (10) 1909-1916; DOI: https://doi.org/10.1124/dmd.112.045682

  3. Fridley, Brooke L.

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  4. Friedrich, Stuart

    1. The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
      Mosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. Hall
      Drug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060

G

  1. Gao, Chunying

    1. Mechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic Characteristics
      Chunying Gao, Hongjian Zhang, Zitao Guo, Tiangeng You, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2012, 40 (10) 2009-2020; DOI: https://doi.org/10.1124/dmd.112.047183

  2. Gao, Song

    1. Breast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of Genistein
      Zhen Yang, Wei Zhu, Song Gao, Taijun Yin, Wen Jiang and Ming Hu
      Drug Metabolism and Disposition October 2012, 40 (10) 1883-1893; DOI: https://doi.org/10.1124/dmd.111.043901

  3. Goldman, Adrian

    1. Human UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation Kinetics
      Hongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe Finel
      Drug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086

  4. Gosset, Philippe

    1. Xenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression Profiles
      Elisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-Guidice
      Drug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896

  5. Guo, Yu

    1. Selective Expression of CYP2A13 in Human Pancreatic α-Islet Cells
      Yu Guo, Liang-Ru Zhu, Gang Lu, Hui Wang and Jun-Yan Hong
      Drug Metabolism and Disposition October 2012, 40 (10) 1878-1882; DOI: https://doi.org/10.1124/dmd.112.046359

  6. Guo, Zitao

    1. Mechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic Characteristics
      Chunying Gao, Hongjian Zhang, Zitao Guo, Tiangeng You, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2012, 40 (10) 2009-2020; DOI: https://doi.org/10.1124/dmd.112.047183

H

  1. Hall, Stephen D.

    1. The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
      Mosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. Hall
      Drug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060

  2. Hao, Gang

    1. Key Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2
      Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji Wang
      Drug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187

  3. Hartman, Jessica H.

    1. CYP2E1 Metabolism of Styrene Involves Allostery
      Jessica H. Hartman, Gunnar Boysen and Grover P. Miller
      Drug Metabolism and Disposition October 2012, 40 (10) 1976-1983; DOI: https://doi.org/10.1124/dmd.112.046698

  4. Hebbring, Scott J.

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  5. Herudzinska, Justyna

    1. Absolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy Subjects
      Guus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham Lappin
      Drug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623

  6. Hill, Dennis

    1. Acetylenic Linkers in Lead Compounds: A Study of the Stability of the Propargyl-Linked Antifolates
      Wangda Zhou, Kishore Viswanathan, Dennis Hill, Amy C. Anderson and Dennis L. Wright
      Drug Metabolism and Disposition October 2012, 40 (10) 2002-2008; DOI: https://doi.org/10.1124/dmd.112.046870

  7. Hofland, Corry

    1. Microdialysis Evaluation of Clozapine and N-Desmethylclozapine Pharmacokinetics in Rat Brain
      Thomas I. F. H. Cremers, Gunnar Flik, Corry Hofland and Robert E. Stratford
      Drug Metabolism and Disposition October 2012, 40 (10) 1909-1916; DOI: https://doi.org/10.1124/dmd.112.045682

  8. Hong, Jun-Yan

    1. Selective Expression of CYP2A13 in Human Pancreatic α-Islet Cells
      Yu Guo, Liang-Ru Zhu, Gang Lu, Hui Wang and Jun-Yan Hong
      Drug Metabolism and Disposition October 2012, 40 (10) 1878-1882; DOI: https://doi.org/10.1124/dmd.112.046359

  9. Hu, Ming

    1. Breast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of Genistein
      Zhen Yang, Wei Zhu, Song Gao, Taijun Yin, Wen Jiang and Ming Hu
      Drug Metabolism and Disposition October 2012, 40 (10) 1883-1893; DOI: https://doi.org/10.1124/dmd.111.043901

  10. Hui, Eric Ka-Wai

    1. Glycemic Control and Chronic Dosing of Rhesus Monkeys with a Fusion Protein of Iduronidase and a Monoclonal Antibody Against the Human Insulin Receptor
      Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition October 2012, 40 (10) 2021-2025; DOI: https://doi.org/10.1124/dmd.112.046375

I

  1. Ikari, Akira

    1. Regulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR Protein
      Junko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748

  2. Ikushiro, Shinichi

    1. Comparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906
    2. Human UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation Kinetics
      Hongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe Finel
      Drug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086

  3. Itoh, Toshimasa

    1. Comparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906

  4. Iwuchukwu, Otito F.

    1. In Vivo-Formed versus Preformed Metabolite Kinetics of trans-Resveratrol-3-sulfate and trans-Resveratrol-3-glucuronide
      Satish Sharan, Otito F. Iwuchukwu, Daniel J. Canney, Cheryl L. Zimmerman and Swati Nagar
      Drug Metabolism and Disposition October 2012, 40 (10) 1993-2001; DOI: https://doi.org/10.1124/dmd.112.046417

J

  1. Jaillard, Sophie

    1. Xenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression Profiles
      Elisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-Guidice
      Drug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896

  2. Jenkins, Gregory D.

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  3. Ji, Yuan

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  4. Jiang, Wen

    1. Breast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of Genistein
      Zhen Yang, Wei Zhu, Song Gao, Taijun Yin, Wen Jiang and Ming Hu
      Drug Metabolism and Disposition October 2012, 40 (10) 1883-1893; DOI: https://doi.org/10.1124/dmd.111.043901

K

  1. Kamakura, Masaki

    1. Comparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906

  2. Kazmi, Faraz

    1. High-Resolution Mass Spectrometry Elucidates Metabonate (False Metabolite) Formation from Alkylamine Drugs during In Vitro Metabolite Profiling
      Joanna E. Barbara, Faraz Kazmi, Seema Muranjan, Paul C. Toren and Andrew Parkinson
      Drug Metabolism and Disposition October 2012, 40 (10) 1966-1975; DOI: https://doi.org/10.1124/dmd.112.047027

  3. Kinloch, Ryan D.

    1. Selective Modulation of Hepatic Cytochrome P450 and Flavin Monooxygenase 3 Expression during Citrobacter rodentium Infection in Severe Combined Immune-Deficient Mice
      Beatrice A. Nyagode, William J. Watkins, Ryan D. Kinloch and Edward T. Morgan
      Drug Metabolism and Disposition October 2012, 40 (10) 1894-1899; DOI: https://doi.org/10.1124/dmd.112.046557

  4. Kurosawa, Masatoshi

    1. Regulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR Protein
      Junko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748

L

  1. Lafitte, Jean-Jacques

    1. Xenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression Profiles
      Elisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-Guidice
      Drug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896

  2. Lappin, Graham

    1. Absolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy Subjects
      Guus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham Lappin
      Drug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623

  3. Leclerc, Julie

    1. Xenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression Profiles
      Elisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-Guidice
      Drug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896

  4. Li, Liang

    1. In Vitro Studies on the Oxidative Metabolism of 20(S)-Ginsenoside Rh2 in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes, and Human Liver S9
      Liang Li, Xiaoyan Chen, Jialan Zhou and Dafang Zhong
      Drug Metabolism and Disposition October 2012, 40 (10) 2041-2053; DOI: https://doi.org/10.1124/dmd.112.046995

  5. Lo-Guidice, Jean-Marc

    1. Xenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression Profiles
      Elisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-Guidice
      Drug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896

  6. Lowe, Stephen L.

    1. The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
      Mosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. Hall
      Drug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060

  7. Lu, Gang

    1. Selective Expression of CYP2A13 in Human Pancreatic α-Islet Cells
      Yu Guo, Liang-Ru Zhu, Gang Lu, Hui Wang and Jun-Yan Hong
      Drug Metabolism and Disposition October 2012, 40 (10) 1878-1882; DOI: https://doi.org/10.1124/dmd.112.046359

  8. Lu, Jeff Zhiqiang

    1. Glycemic Control and Chronic Dosing of Rhesus Monkeys with a Fusion Protein of Iduronidase and a Monoclonal Antibody Against the Human Insulin Receptor
      Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition October 2012, 40 (10) 2021-2025; DOI: https://doi.org/10.1124/dmd.112.046375

  9. Lu, Meng

    1. Key Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2
      Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji Wang
      Drug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187

M

  1. Mackenzie, Peter I.

    1. Human UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation Kinetics
      Hongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe Finel
      Drug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086

  2. Mensier, Eric

    1. Xenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression Profiles
      Elisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-Guidice
      Drug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896

  3. Miller, Grover P.

    1. CYP2E1 Metabolism of Styrene Involves Allostery
      Jessica H. Hartman, Gunnar Boysen and Grover P. Miller
      Drug Metabolism and Disposition October 2012, 40 (10) 1976-1983; DOI: https://doi.org/10.1124/dmd.112.046698

  4. Miwa, Masao

    1. Regulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR Protein
      Junko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748

  5. Moon, Irene

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  6. Morgan, Edward T.

    1. Selective Modulation of Hepatic Cytochrome P450 and Flavin Monooxygenase 3 Expression during Citrobacter rodentium Infection in Severe Combined Immune-Deficient Mice
      Beatrice A. Nyagode, William J. Watkins, Ryan D. Kinloch and Edward T. Morgan
      Drug Metabolism and Disposition October 2012, 40 (10) 1894-1899; DOI: https://doi.org/10.1124/dmd.112.046557

  7. Müller, Markus

    1. Absolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy Subjects
      Guus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham Lappin
      Drug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623

  8. Munetsuna, Eiji

    1. Comparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906

  9. Muranjan, Seema

    1. High-Resolution Mass Spectrometry Elucidates Metabonate (False Metabolite) Formation from Alkylamine Drugs during In Vitro Metabolite Profiling
      Joanna E. Barbara, Faraz Kazmi, Seema Muranjan, Paul C. Toren and Andrew Parkinson
      Drug Metabolism and Disposition October 2012, 40 (10) 1966-1975; DOI: https://doi.org/10.1124/dmd.112.047027

N

  1. Nagar, Swati

    1. In Vivo-Formed versus Preformed Metabolite Kinetics of trans-Resveratrol-3-sulfate and trans-Resveratrol-3-glucuronide
      Satish Sharan, Otito F. Iwuchukwu, Daniel J. Canney, Cheryl L. Zimmerman and Swati Nagar
      Drug Metabolism and Disposition October 2012, 40 (10) 1993-2001; DOI: https://doi.org/10.1124/dmd.112.046417

  2. Nordgren, Kendra K. S.

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  3. Nyagode, Beatrice A.

    1. Selective Modulation of Hepatic Cytochrome P450 and Flavin Monooxygenase 3 Expression during Citrobacter rodentium Infection in Severe Combined Immune-Deficient Mice
      Beatrice A. Nyagode, William J. Watkins, Ryan D. Kinloch and Edward T. Morgan
      Drug Metabolism and Disposition October 2012, 40 (10) 1894-1899; DOI: https://doi.org/10.1124/dmd.112.046557

O

  1. Ohta, Miho

    1. Comparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906

P

  1. Pang, K. Sandy

    1. Commentary: Theoretical Predictions of Flow Effects on Intestinal and Systemic Availability in Physiologically Based Pharmacokinetic Intestine Models: The Traditional Model, Segregated Flow Model, and QGut Model
      K. Sandy Pang and Edwin C. Y. Chow
      Drug Metabolism and Disposition October 2012, 40 (10) 1869-1877; DOI: https://doi.org/10.1124/dmd.112.045872

  2. Pardridge, William M.

    1. Glycemic Control and Chronic Dosing of Rhesus Monkeys with a Fusion Protein of Iduronidase and a Monoclonal Antibody Against the Human Insulin Receptor
      Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. Pardridge
      Drug Metabolism and Disposition October 2012, 40 (10) 2021-2025; DOI: https://doi.org/10.1124/dmd.112.046375

  3. Parkinson, Andrew

    1. High-Resolution Mass Spectrometry Elucidates Metabonate (False Metabolite) Formation from Alkylamine Drugs during In Vitro Metabolite Profiling
      Joanna E. Barbara, Faraz Kazmi, Seema Muranjan, Paul C. Toren and Andrew Parkinson
      Drug Metabolism and Disposition October 2012, 40 (10) 1966-1975; DOI: https://doi.org/10.1124/dmd.112.047027

  4. Patana, Anne-Sisko

    1. Human UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation Kinetics
      Hongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe Finel
      Drug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086

  5. Pearson, Josh T.

    1. In Vitro Characterization of the Drug-Drug Interaction Potential of Catabolites of Antibody-Maytansinoid Conjugates
      John A. Davis, Dan A. Rock, Larry C. Wienkers and Josh T. Pearson
      Drug Metabolism and Disposition October 2012, 40 (10) 1927-1934; DOI: https://doi.org/10.1124/dmd.112.046169

  6. Pelleymounter, Linda L.

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  7. Peng, Yi

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  8. Pottier, Nicolas

    1. Xenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression Profiles
      Elisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-Guidice
      Drug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896

R

  1. Rock, Dan A.

    1. In Vitro Characterization of the Drug-Drug Interaction Potential of Catabolites of Antibody-Maytansinoid Conjugates
      John A. Davis, Dan A. Rock, Larry C. Wienkers and Josh T. Pearson
      Drug Metabolism and Disposition October 2012, 40 (10) 1927-1934; DOI: https://doi.org/10.1124/dmd.112.046169

S

  1. Sakaki, Toshiyuki

    1. Comparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906

  2. Sanghera, Davindera

    1. Absolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy Subjects
      Guus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham Lappin
      Drug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623

  3. Sharan, Satish

    1. In Vivo-Formed versus Preformed Metabolite Kinetics of trans-Resveratrol-3-sulfate and trans-Resveratrol-3-glucuronide
      Satish Sharan, Otito F. Iwuchukwu, Daniel J. Canney, Cheryl L. Zimmerman and Swati Nagar
      Drug Metabolism and Disposition October 2012, 40 (10) 1993-2001; DOI: https://doi.org/10.1124/dmd.112.046417

  4. Shirali, Pirouz

    1. Xenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression Profiles
      Elisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-Guidice
      Drug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896

  5. Stratford, Robert E.

    1. Microdialysis Evaluation of Clozapine and N-Desmethylclozapine Pharmacokinetics in Rat Brain
      Thomas I. F. H. Cremers, Gunnar Flik, Corry Hofland and Robert E. Stratford
      Drug Metabolism and Disposition October 2012, 40 (10) 1909-1916; DOI: https://doi.org/10.1124/dmd.112.045682

  6. Sugatani, Junko

    1. Regulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR Protein
      Junko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748

  7. Sun, Haopeng

    1. Key Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2
      Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji Wang
      Drug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187

T

  1. Toren, Paul C.

    1. High-Resolution Mass Spectrometry Elucidates Metabonate (False Metabolite) Formation from Alkylamine Drugs during In Vitro Metabolite Profiling
      Joanna E. Barbara, Faraz Kazmi, Seema Muranjan, Paul C. Toren and Andrew Parkinson
      Drug Metabolism and Disposition October 2012, 40 (10) 1966-1975; DOI: https://doi.org/10.1124/dmd.112.047027

U

  1. Uchida, Takahiro

    1. Regulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR Protein
      Junko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748

V

  1. Viswanathan, Kishore

    1. Acetylenic Linkers in Lead Compounds: A Study of the Stability of the Propargyl-Linked Antifolates
      Wangda Zhou, Kishore Viswanathan, Dennis Hill, Amy C. Anderson and Dennis L. Wright
      Drug Metabolism and Disposition October 2012, 40 (10) 2002-2008; DOI: https://doi.org/10.1124/dmd.112.046870

W

  1. Wakayama, Shuto

    1. Comparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906

  2. Wang, Guangji

    1. Key Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2
      Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji Wang
      Drug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187

  3. Wang, Hui

    1. Selective Expression of CYP2A13 in Human Pancreatic α-Islet Cells
      Yu Guo, Liang-Ru Zhu, Gang Lu, Hui Wang and Jun-Yan Hong
      Drug Metabolism and Disposition October 2012, 40 (10) 1878-1882; DOI: https://doi.org/10.1124/dmd.112.046359

  4. Watkins, William J.

    1. Selective Modulation of Hepatic Cytochrome P450 and Flavin Monooxygenase 3 Expression during Citrobacter rodentium Infection in Severe Combined Immune-Deficient Mice
      Beatrice A. Nyagode, William J. Watkins, Ryan D. Kinloch and Edward T. Morgan
      Drug Metabolism and Disposition October 2012, 40 (10) 1894-1899; DOI: https://doi.org/10.1124/dmd.112.046557

  5. Weinshilboum, Richard M.

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  6. Wieben, Eric D.

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  7. Wienkers, Larry C.

    1. In Vitro Characterization of the Drug-Drug Interaction Potential of Catabolites of Antibody-Maytansinoid Conjugates
      John A. Davis, Dan A. Rock, Larry C. Wienkers and Josh T. Pearson
      Drug Metabolism and Disposition October 2012, 40 (10) 1927-1934; DOI: https://doi.org/10.1124/dmd.112.046169

  8. Willis, Brian A.

    1. The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
      Mosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. Hall
      Drug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060

  9. Windebank, Sam

    1. Absolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy Subjects
      Guus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham Lappin
      Drug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623

  10. Wise, Stephen D.

    1. The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
      Mosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. Hall
      Drug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060

  11. Wright, Dennis L.

    1. Acetylenic Linkers in Lead Compounds: A Study of the Stability of the Propargyl-Linked Antifolates
      Wangda Zhou, Kishore Viswanathan, Dennis Hill, Amy C. Anderson and Dennis L. Wright
      Drug Metabolism and Disposition October 2012, 40 (10) 2002-2008; DOI: https://doi.org/10.1124/dmd.112.046870

  12. Wu, Xiaolan

    1. Key Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2
      Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji Wang
      Drug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187

Y

  1. Yamaguchi, Masahiko

    1. Regulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR Protein
      Junko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748

  2. Yamamoto, Keiko

    1. Comparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906

  3. Yamazaki, Yasuhiro

    1. Regulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR Protein
      Junko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao Miwa
      Drug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748

  4. Yang, Zhen

    1. Breast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of Genistein
      Zhen Yang, Wei Zhu, Song Gao, Taijun Yin, Wen Jiang and Ming Hu
      Drug Metabolism and Disposition October 2012, 40 (10) 1883-1893; DOI: https://doi.org/10.1124/dmd.111.043901

  5. Yasuda, Kaori

    1. Comparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human Liver
      Kaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki Sakaki
      Drug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906

  6. Yee, Vivien C.

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  7. Yin, Taijun

    1. Breast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of Genistein
      Zhen Yang, Wei Zhu, Song Gao, Taijun Yin, Wen Jiang and Ming Hu
      Drug Metabolism and Disposition October 2012, 40 (10) 1883-1893; DOI: https://doi.org/10.1124/dmd.111.043901

  8. You, Tiangeng

    1. Mechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic Characteristics
      Chunying Gao, Hongjian Zhang, Zitao Guo, Tiangeng You, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2012, 40 (10) 2009-2020; DOI: https://doi.org/10.1124/dmd.112.047183

Z

  1. Zeitlinger, Markus

    1. Absolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy Subjects
      Guus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham Lappin
      Drug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623

  2. Zhang, Hongbo

    1. Human UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation Kinetics
      Hongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe Finel
      Drug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086

  3. Zhang, Hongjian

    1. Mechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic Characteristics
      Chunying Gao, Hongjian Zhang, Zitao Guo, Tiangeng You, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2012, 40 (10) 2009-2020; DOI: https://doi.org/10.1124/dmd.112.047183

  4. Zhang, Jianping

    1. Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation
      Yuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953

  5. Zhang, Jingwei

    1. Key Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2
      Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji Wang
      Drug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187

  6. Zhang, Wei

    1. The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
      Mosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. Hall
      Drug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060

  7. Zhong, Dafang

    1. In Vitro Studies on the Oxidative Metabolism of 20(S)-Ginsenoside Rh2 in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes, and Human Liver S9
      Liang Li, Xiaoyan Chen, Jialan Zhou and Dafang Zhong
      Drug Metabolism and Disposition October 2012, 40 (10) 2041-2053; DOI: https://doi.org/10.1124/dmd.112.046995
    2. Mechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic Characteristics
      Chunying Gao, Hongjian Zhang, Zitao Guo, Tiangeng You, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2012, 40 (10) 2009-2020; DOI: https://doi.org/10.1124/dmd.112.047183

  8. Zhou, Fang

    1. Key Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2
      Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji Wang
      Drug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187

  9. Zhou, Jialan

    1. In Vitro Studies on the Oxidative Metabolism of 20(S)-Ginsenoside Rh2 in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes, and Human Liver S9
      Liang Li, Xiaoyan Chen, Jialan Zhou and Dafang Zhong
      Drug Metabolism and Disposition October 2012, 40 (10) 2041-2053; DOI: https://doi.org/10.1124/dmd.112.046995

  10. Zhou, Wangda

    1. Acetylenic Linkers in Lead Compounds: A Study of the Stability of the Propargyl-Linked Antifolates
      Wangda Zhou, Kishore Viswanathan, Dennis Hill, Amy C. Anderson and Dennis L. Wright
      Drug Metabolism and Disposition October 2012, 40 (10) 2002-2008; DOI: https://doi.org/10.1124/dmd.112.046870

  11. Zhu, Liang-Ru

    1. Selective Expression of CYP2A13 in Human Pancreatic α-Islet Cells
      Yu Guo, Liang-Ru Zhu, Gang Lu, Hui Wang and Jun-Yan Hong
      Drug Metabolism and Disposition October 2012, 40 (10) 1878-1882; DOI: https://doi.org/10.1124/dmd.112.046359

  12. Zhu, Wei

    1. Breast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of Genistein
      Zhen Yang, Wei Zhu, Song Gao, Taijun Yin, Wen Jiang and Ming Hu
      Drug Metabolism and Disposition October 2012, 40 (10) 1883-1893; DOI: https://doi.org/10.1124/dmd.111.043901

  13. Zimmerman, Cheryl L.

    1. In Vivo-Formed versus Preformed Metabolite Kinetics of trans-Resveratrol-3-sulfate and trans-Resveratrol-3-glucuronide
      Satish Sharan, Otito F. Iwuchukwu, Daniel J. Canney, Cheryl L. Zimmerman and Swati Nagar
      Drug Metabolism and Disposition October 2012, 40 (10) 1993-2001; DOI: https://doi.org/10.1124/dmd.112.046417
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