Index by author
October 01, 2012; Volume 40,Issue 10
A
Abo, Ryan P.
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Anderson, Amy C.
- You have accessAcetylenic Linkers in Lead Compounds: A Study of the Stability of the Propargyl-Linked AntifolatesWangda Zhou, Kishore Viswanathan, Dennis Hill, Amy C. Anderson and Dennis L. WrightDrug Metabolism and Disposition October 2012, 40 (10) 2002-2008; DOI: https://doi.org/10.1124/dmd.112.046870
Annes, William F.
- You have accessThe Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, KetoconazoleMosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. HallDrug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060
Ayan-Oshodi, Mosun A.
- You have accessThe Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, KetoconazoleMosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. HallDrug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060
B
Barbara, Joanna E.
- You have accessHigh-Resolution Mass Spectrometry Elucidates Metabonate (False Metabolite) Formation from Alkylamine Drugs during In Vitro Metabolite ProfilingJoanna E. Barbara, Faraz Kazmi, Seema Muranjan, Paul C. Toren and Andrew ParkinsonDrug Metabolism and Disposition October 2012, 40 (10) 1966-1975; DOI: https://doi.org/10.1124/dmd.112.047027
Boado, Ruben J.
- You have accessGlycemic Control and Chronic Dosing of Rhesus Monkeys with a Fusion Protein of Iduronidase and a Monoclonal Antibody Against the Human Insulin ReceptorRuben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. PardridgeDrug Metabolism and Disposition October 2012, 40 (10) 2021-2025; DOI: https://doi.org/10.1124/dmd.112.046375
Boysen, Gunnar
- You have accessCYP2E1 Metabolism of Styrene Involves AllosteryJessica H. Hartman, Gunnar Boysen and Grover P. MillerDrug Metabolism and Disposition October 2012, 40 (10) 1976-1983; DOI: https://doi.org/10.1124/dmd.112.046698
Broly, Franck
- You have accessXenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression ProfilesElisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-GuidiceDrug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896
Brown, Thomas
- You have accessThe Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, KetoconazoleMosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. HallDrug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060
Burian, Angela
- You have accessAbsolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy SubjectsGuus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham LappinDrug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623
C
Canney, Daniel J.
- You have accessIn Vivo-Formed versus Preformed Metabolite Kinetics of trans-Resveratrol-3-sulfate and trans-Resveratrol-3-glucuronideSatish Sharan, Otito F. Iwuchukwu, Daniel J. Canney, Cheryl L. Zimmerman and Swati NagarDrug Metabolism and Disposition October 2012, 40 (10) 1993-2001; DOI: https://doi.org/10.1124/dmd.112.046417
Chai, Xiaoshan
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Chai, Yubo
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Chen, Xiaoyan
- You have accessIn Vitro Studies on the Oxidative Metabolism of 20(S)-Ginsenoside Rh2 in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes, and Human Liver S9Liang Li, Xiaoyan Chen, Jialan Zhou and Dafang ZhongDrug Metabolism and Disposition October 2012, 40 (10) 2041-2053; DOI: https://doi.org/10.1124/dmd.112.046995
- You have accessMechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic CharacteristicsChunying Gao, Hongjian Zhang, Zitao Guo, Tiangeng You, Xiaoyan Chen and Dafang ZhongDrug Metabolism and Disposition October 2012, 40 (10) 2009-2020; DOI: https://doi.org/10.1124/dmd.112.047183
Chow, Edwin C. Y.
- You have accessCommentary: Theoretical Predictions of Flow Effects on Intestinal and Systemic Availability in Physiologically Based Pharmacokinetic Intestine Models: The Traditional Model, Segregated Flow Model, and QGut ModelK. Sandy Pang and Edwin C. Y. ChowDrug Metabolism and Disposition October 2012, 40 (10) 1869-1877; DOI: https://doi.org/10.1124/dmd.112.045872
Cochrane, Brett
- You have accessAbsolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy SubjectsGuus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham LappinDrug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623
Courcot, Elisabeth
- You have accessXenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression ProfilesElisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-GuidiceDrug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896
Cremers, Thomas I. F. H.
- You have accessMicrodialysis Evaluation of Clozapine and N-Desmethylclozapine Pharmacokinetics in Rat BrainThomas I. F. H. Cremers, Gunnar Flik, Corry Hofland and Robert E. StratfordDrug Metabolism and Disposition October 2012, 40 (10) 1909-1916; DOI: https://doi.org/10.1124/dmd.112.045682
D
Davis, John A.
- You have accessIn Vitro Characterization of the Drug-Drug Interaction Potential of Catabolites of Antibody-Maytansinoid ConjugatesJohn A. Davis, Dan A. Rock, Larry C. Wienkers and Josh T. PearsonDrug Metabolism and Disposition October 2012, 40 (10) 1927-1934; DOI: https://doi.org/10.1124/dmd.112.046169
de la Peña, Amparo
- You have accessThe Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, KetoconazoleMosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. HallDrug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060
Duchateau, Guus
- You have accessAbsolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy SubjectsGuus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham LappinDrug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623
E
Eckloff, Bruce W.
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
F
Finel, Moshe
- You have accessHuman UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation KineticsHongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe FinelDrug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086
Flik, Gunnar
- You have accessMicrodialysis Evaluation of Clozapine and N-Desmethylclozapine Pharmacokinetics in Rat BrainThomas I. F. H. Cremers, Gunnar Flik, Corry Hofland and Robert E. StratfordDrug Metabolism and Disposition October 2012, 40 (10) 1909-1916; DOI: https://doi.org/10.1124/dmd.112.045682
Fridley, Brooke L.
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Friedrich, Stuart
- You have accessThe Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, KetoconazoleMosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. HallDrug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060
G
Gao, Chunying
- You have accessMechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic CharacteristicsChunying Gao, Hongjian Zhang, Zitao Guo, Tiangeng You, Xiaoyan Chen and Dafang ZhongDrug Metabolism and Disposition October 2012, 40 (10) 2009-2020; DOI: https://doi.org/10.1124/dmd.112.047183
Gao, Song
- You have accessBreast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of GenisteinZhen Yang, Wei Zhu, Song Gao, Taijun Yin, Wen Jiang and Ming HuDrug Metabolism and Disposition October 2012, 40 (10) 1883-1893; DOI: https://doi.org/10.1124/dmd.111.043901
Goldman, Adrian
- You have accessHuman UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation KineticsHongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe FinelDrug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086
Gosset, Philippe
- You have accessXenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression ProfilesElisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-GuidiceDrug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896
Guo, Yu
- You have accessSelective Expression of CYP2A13 in Human Pancreatic α-Islet CellsYu Guo, Liang-Ru Zhu, Gang Lu, Hui Wang and Jun-Yan HongDrug Metabolism and Disposition October 2012, 40 (10) 1878-1882; DOI: https://doi.org/10.1124/dmd.112.046359
Guo, Zitao
- You have accessMechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic CharacteristicsChunying Gao, Hongjian Zhang, Zitao Guo, Tiangeng You, Xiaoyan Chen and Dafang ZhongDrug Metabolism and Disposition October 2012, 40 (10) 2009-2020; DOI: https://doi.org/10.1124/dmd.112.047183
H
Hall, Stephen D.
- You have accessThe Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, KetoconazoleMosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. HallDrug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060
Hao, Gang
- You have accessKey Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji WangDrug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187
Hartman, Jessica H.
- You have accessCYP2E1 Metabolism of Styrene Involves AllosteryJessica H. Hartman, Gunnar Boysen and Grover P. MillerDrug Metabolism and Disposition October 2012, 40 (10) 1976-1983; DOI: https://doi.org/10.1124/dmd.112.046698
Hebbring, Scott J.
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Herudzinska, Justyna
- You have accessAbsolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy SubjectsGuus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham LappinDrug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623
Hill, Dennis
- You have accessAcetylenic Linkers in Lead Compounds: A Study of the Stability of the Propargyl-Linked AntifolatesWangda Zhou, Kishore Viswanathan, Dennis Hill, Amy C. Anderson and Dennis L. WrightDrug Metabolism and Disposition October 2012, 40 (10) 2002-2008; DOI: https://doi.org/10.1124/dmd.112.046870
Hofland, Corry
- You have accessMicrodialysis Evaluation of Clozapine and N-Desmethylclozapine Pharmacokinetics in Rat BrainThomas I. F. H. Cremers, Gunnar Flik, Corry Hofland and Robert E. StratfordDrug Metabolism and Disposition October 2012, 40 (10) 1909-1916; DOI: https://doi.org/10.1124/dmd.112.045682
Hong, Jun-Yan
- You have accessSelective Expression of CYP2A13 in Human Pancreatic α-Islet CellsYu Guo, Liang-Ru Zhu, Gang Lu, Hui Wang and Jun-Yan HongDrug Metabolism and Disposition October 2012, 40 (10) 1878-1882; DOI: https://doi.org/10.1124/dmd.112.046359
Hu, Ming
- You have accessBreast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of GenisteinZhen Yang, Wei Zhu, Song Gao, Taijun Yin, Wen Jiang and Ming HuDrug Metabolism and Disposition October 2012, 40 (10) 1883-1893; DOI: https://doi.org/10.1124/dmd.111.043901
Hui, Eric Ka-Wai
- You have accessGlycemic Control and Chronic Dosing of Rhesus Monkeys with a Fusion Protein of Iduronidase and a Monoclonal Antibody Against the Human Insulin ReceptorRuben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. PardridgeDrug Metabolism and Disposition October 2012, 40 (10) 2021-2025; DOI: https://doi.org/10.1124/dmd.112.046375
I
Ikari, Akira
- You have accessRegulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR ProteinJunko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao MiwaDrug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748
Ikushiro, Shinichi
- You have accessComparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human LiverKaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906
- You have accessHuman UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation KineticsHongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe FinelDrug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086
Itoh, Toshimasa
- You have accessComparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human LiverKaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906
Iwuchukwu, Otito F.
- You have accessIn Vivo-Formed versus Preformed Metabolite Kinetics of trans-Resveratrol-3-sulfate and trans-Resveratrol-3-glucuronideSatish Sharan, Otito F. Iwuchukwu, Daniel J. Canney, Cheryl L. Zimmerman and Swati NagarDrug Metabolism and Disposition October 2012, 40 (10) 1993-2001; DOI: https://doi.org/10.1124/dmd.112.046417
J
Jaillard, Sophie
- You have accessXenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression ProfilesElisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-GuidiceDrug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896
Jenkins, Gregory D.
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Ji, Yuan
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Jiang, Wen
- You have accessBreast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of GenisteinZhen Yang, Wei Zhu, Song Gao, Taijun Yin, Wen Jiang and Ming HuDrug Metabolism and Disposition October 2012, 40 (10) 1883-1893; DOI: https://doi.org/10.1124/dmd.111.043901
K
Kamakura, Masaki
- You have accessComparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human LiverKaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906
Kazmi, Faraz
- You have accessHigh-Resolution Mass Spectrometry Elucidates Metabonate (False Metabolite) Formation from Alkylamine Drugs during In Vitro Metabolite ProfilingJoanna E. Barbara, Faraz Kazmi, Seema Muranjan, Paul C. Toren and Andrew ParkinsonDrug Metabolism and Disposition October 2012, 40 (10) 1966-1975; DOI: https://doi.org/10.1124/dmd.112.047027
Kinloch, Ryan D.
- You have accessSelective Modulation of Hepatic Cytochrome P450 and Flavin Monooxygenase 3 Expression during Citrobacter rodentium Infection in Severe Combined Immune-Deficient MiceBeatrice A. Nyagode, William J. Watkins, Ryan D. Kinloch and Edward T. MorganDrug Metabolism and Disposition October 2012, 40 (10) 1894-1899; DOI: https://doi.org/10.1124/dmd.112.046557
Kurosawa, Masatoshi
- You have accessRegulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR ProteinJunko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao MiwaDrug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748
L
Lafitte, Jean-Jacques
- You have accessXenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression ProfilesElisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-GuidiceDrug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896
Lappin, Graham
- You have accessAbsolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy SubjectsGuus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham LappinDrug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623
Leclerc, Julie
- You have accessXenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression ProfilesElisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-GuidiceDrug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896
Li, Liang
- You have accessIn Vitro Studies on the Oxidative Metabolism of 20(S)-Ginsenoside Rh2 in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes, and Human Liver S9Liang Li, Xiaoyan Chen, Jialan Zhou and Dafang ZhongDrug Metabolism and Disposition October 2012, 40 (10) 2041-2053; DOI: https://doi.org/10.1124/dmd.112.046995
Lo-Guidice, Jean-Marc
- You have accessXenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression ProfilesElisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-GuidiceDrug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896
Lowe, Stephen L.
- You have accessThe Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, KetoconazoleMosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. HallDrug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060
Lu, Gang
- You have accessSelective Expression of CYP2A13 in Human Pancreatic α-Islet CellsYu Guo, Liang-Ru Zhu, Gang Lu, Hui Wang and Jun-Yan HongDrug Metabolism and Disposition October 2012, 40 (10) 1878-1882; DOI: https://doi.org/10.1124/dmd.112.046359
Lu, Jeff Zhiqiang
- You have accessGlycemic Control and Chronic Dosing of Rhesus Monkeys with a Fusion Protein of Iduronidase and a Monoclonal Antibody Against the Human Insulin ReceptorRuben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. PardridgeDrug Metabolism and Disposition October 2012, 40 (10) 2021-2025; DOI: https://doi.org/10.1124/dmd.112.046375
Lu, Meng
- You have accessKey Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji WangDrug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187
M
Mackenzie, Peter I.
- You have accessHuman UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation KineticsHongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe FinelDrug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086
Mensier, Eric
- You have accessXenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression ProfilesElisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-GuidiceDrug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896
Miller, Grover P.
- You have accessCYP2E1 Metabolism of Styrene Involves AllosteryJessica H. Hartman, Gunnar Boysen and Grover P. MillerDrug Metabolism and Disposition October 2012, 40 (10) 1976-1983; DOI: https://doi.org/10.1124/dmd.112.046698
Miwa, Masao
- You have accessRegulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR ProteinJunko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao MiwaDrug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748
Moon, Irene
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Morgan, Edward T.
- You have accessSelective Modulation of Hepatic Cytochrome P450 and Flavin Monooxygenase 3 Expression during Citrobacter rodentium Infection in Severe Combined Immune-Deficient MiceBeatrice A. Nyagode, William J. Watkins, Ryan D. Kinloch and Edward T. MorganDrug Metabolism and Disposition October 2012, 40 (10) 1894-1899; DOI: https://doi.org/10.1124/dmd.112.046557
Müller, Markus
- You have accessAbsolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy SubjectsGuus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham LappinDrug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623
Munetsuna, Eiji
- You have accessComparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human LiverKaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906
Muranjan, Seema
- You have accessHigh-Resolution Mass Spectrometry Elucidates Metabonate (False Metabolite) Formation from Alkylamine Drugs during In Vitro Metabolite ProfilingJoanna E. Barbara, Faraz Kazmi, Seema Muranjan, Paul C. Toren and Andrew ParkinsonDrug Metabolism and Disposition October 2012, 40 (10) 1966-1975; DOI: https://doi.org/10.1124/dmd.112.047027
N
Nagar, Swati
- You have accessIn Vivo-Formed versus Preformed Metabolite Kinetics of trans-Resveratrol-3-sulfate and trans-Resveratrol-3-glucuronideSatish Sharan, Otito F. Iwuchukwu, Daniel J. Canney, Cheryl L. Zimmerman and Swati NagarDrug Metabolism and Disposition October 2012, 40 (10) 1993-2001; DOI: https://doi.org/10.1124/dmd.112.046417
Nordgren, Kendra K. S.
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Nyagode, Beatrice A.
- You have accessSelective Modulation of Hepatic Cytochrome P450 and Flavin Monooxygenase 3 Expression during Citrobacter rodentium Infection in Severe Combined Immune-Deficient MiceBeatrice A. Nyagode, William J. Watkins, Ryan D. Kinloch and Edward T. MorganDrug Metabolism and Disposition October 2012, 40 (10) 1894-1899; DOI: https://doi.org/10.1124/dmd.112.046557
O
Ohta, Miho
- You have accessComparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human LiverKaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906
P
Pang, K. Sandy
- You have accessCommentary: Theoretical Predictions of Flow Effects on Intestinal and Systemic Availability in Physiologically Based Pharmacokinetic Intestine Models: The Traditional Model, Segregated Flow Model, and QGut ModelK. Sandy Pang and Edwin C. Y. ChowDrug Metabolism and Disposition October 2012, 40 (10) 1869-1877; DOI: https://doi.org/10.1124/dmd.112.045872
Pardridge, William M.
- You have accessGlycemic Control and Chronic Dosing of Rhesus Monkeys with a Fusion Protein of Iduronidase and a Monoclonal Antibody Against the Human Insulin ReceptorRuben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu and William M. PardridgeDrug Metabolism and Disposition October 2012, 40 (10) 2021-2025; DOI: https://doi.org/10.1124/dmd.112.046375
Parkinson, Andrew
- You have accessHigh-Resolution Mass Spectrometry Elucidates Metabonate (False Metabolite) Formation from Alkylamine Drugs during In Vitro Metabolite ProfilingJoanna E. Barbara, Faraz Kazmi, Seema Muranjan, Paul C. Toren and Andrew ParkinsonDrug Metabolism and Disposition October 2012, 40 (10) 1966-1975; DOI: https://doi.org/10.1124/dmd.112.047027
Patana, Anne-Sisko
- You have accessHuman UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation KineticsHongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe FinelDrug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086
Pearson, Josh T.
- You have accessIn Vitro Characterization of the Drug-Drug Interaction Potential of Catabolites of Antibody-Maytansinoid ConjugatesJohn A. Davis, Dan A. Rock, Larry C. Wienkers and Josh T. PearsonDrug Metabolism and Disposition October 2012, 40 (10) 1927-1934; DOI: https://doi.org/10.1124/dmd.112.046169
Pelleymounter, Linda L.
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Peng, Yi
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Pottier, Nicolas
- You have accessXenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression ProfilesElisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-GuidiceDrug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896
R
Rock, Dan A.
- You have accessIn Vitro Characterization of the Drug-Drug Interaction Potential of Catabolites of Antibody-Maytansinoid ConjugatesJohn A. Davis, Dan A. Rock, Larry C. Wienkers and Josh T. PearsonDrug Metabolism and Disposition October 2012, 40 (10) 1927-1934; DOI: https://doi.org/10.1124/dmd.112.046169
S
Sakaki, Toshiyuki
- You have accessComparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human LiverKaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906
Sanghera, Davindera
- You have accessAbsolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy SubjectsGuus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham LappinDrug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623
Sharan, Satish
- You have accessIn Vivo-Formed versus Preformed Metabolite Kinetics of trans-Resveratrol-3-sulfate and trans-Resveratrol-3-glucuronideSatish Sharan, Otito F. Iwuchukwu, Daniel J. Canney, Cheryl L. Zimmerman and Swati NagarDrug Metabolism and Disposition October 2012, 40 (10) 1993-2001; DOI: https://doi.org/10.1124/dmd.112.046417
Shirali, Pirouz
- You have accessXenobiotic Metabolism and Disposition in Human Lung Cell Models: Comparison with In Vivo Expression ProfilesElisabeth Courcot, Julie Leclerc, Jean-Jacques Lafitte, Eric Mensier, Sophie Jaillard, Philippe Gosset, Pirouz Shirali, Nicolas Pottier, Franck Broly and Jean-Marc Lo-GuidiceDrug Metabolism and Disposition October 2012, 40 (10) 1953-1965; DOI: https://doi.org/10.1124/dmd.112.046896
Stratford, Robert E.
- You have accessMicrodialysis Evaluation of Clozapine and N-Desmethylclozapine Pharmacokinetics in Rat BrainThomas I. F. H. Cremers, Gunnar Flik, Corry Hofland and Robert E. StratfordDrug Metabolism and Disposition October 2012, 40 (10) 1909-1916; DOI: https://doi.org/10.1124/dmd.112.045682
Sugatani, Junko
- You have accessRegulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR ProteinJunko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao MiwaDrug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748
Sun, Haopeng
- You have accessKey Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji WangDrug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187
T
Toren, Paul C.
- You have accessHigh-Resolution Mass Spectrometry Elucidates Metabonate (False Metabolite) Formation from Alkylamine Drugs during In Vitro Metabolite ProfilingJoanna E. Barbara, Faraz Kazmi, Seema Muranjan, Paul C. Toren and Andrew ParkinsonDrug Metabolism and Disposition October 2012, 40 (10) 1966-1975; DOI: https://doi.org/10.1124/dmd.112.047027
U
Uchida, Takahiro
- You have accessRegulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR ProteinJunko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao MiwaDrug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748
V
Viswanathan, Kishore
- You have accessAcetylenic Linkers in Lead Compounds: A Study of the Stability of the Propargyl-Linked AntifolatesWangda Zhou, Kishore Viswanathan, Dennis Hill, Amy C. Anderson and Dennis L. WrightDrug Metabolism and Disposition October 2012, 40 (10) 2002-2008; DOI: https://doi.org/10.1124/dmd.112.046870
W
Wakayama, Shuto
- You have accessComparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human LiverKaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906
Wang, Guangji
- You have accessKey Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji WangDrug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187
Wang, Hui
- You have accessSelective Expression of CYP2A13 in Human Pancreatic α-Islet CellsYu Guo, Liang-Ru Zhu, Gang Lu, Hui Wang and Jun-Yan HongDrug Metabolism and Disposition October 2012, 40 (10) 1878-1882; DOI: https://doi.org/10.1124/dmd.112.046359
Watkins, William J.
- You have accessSelective Modulation of Hepatic Cytochrome P450 and Flavin Monooxygenase 3 Expression during Citrobacter rodentium Infection in Severe Combined Immune-Deficient MiceBeatrice A. Nyagode, William J. Watkins, Ryan D. Kinloch and Edward T. MorganDrug Metabolism and Disposition October 2012, 40 (10) 1894-1899; DOI: https://doi.org/10.1124/dmd.112.046557
Weinshilboum, Richard M.
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Wieben, Eric D.
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Wienkers, Larry C.
- You have accessIn Vitro Characterization of the Drug-Drug Interaction Potential of Catabolites of Antibody-Maytansinoid ConjugatesJohn A. Davis, Dan A. Rock, Larry C. Wienkers and Josh T. PearsonDrug Metabolism and Disposition October 2012, 40 (10) 1927-1934; DOI: https://doi.org/10.1124/dmd.112.046169
Willis, Brian A.
- You have accessThe Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, KetoconazoleMosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. HallDrug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060
Windebank, Sam
- You have accessAbsolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy SubjectsGuus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham LappinDrug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623
Wise, Stephen D.
- You have accessThe Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, KetoconazoleMosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. HallDrug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060
Wright, Dennis L.
- You have accessAcetylenic Linkers in Lead Compounds: A Study of the Stability of the Propargyl-Linked AntifolatesWangda Zhou, Kishore Viswanathan, Dennis Hill, Amy C. Anderson and Dennis L. WrightDrug Metabolism and Disposition October 2012, 40 (10) 2002-2008; DOI: https://doi.org/10.1124/dmd.112.046870
Wu, Xiaolan
- You have accessKey Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji WangDrug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187
Y
Yamaguchi, Masahiko
- You have accessRegulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR ProteinJunko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao MiwaDrug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748
Yamamoto, Keiko
- You have accessComparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human LiverKaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906
Yamazaki, Yasuhiro
- You have accessRegulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR ProteinJunko Sugatani, Takahiro Uchida, Masatoshi Kurosawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari and Masao MiwaDrug Metabolism and Disposition October 2012, 40 (10) 2031-2040; DOI: https://doi.org/10.1124/dmd.112.046748
Yang, Zhen
- You have accessBreast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of GenisteinZhen Yang, Wei Zhu, Song Gao, Taijun Yin, Wen Jiang and Ming HuDrug Metabolism and Disposition October 2012, 40 (10) 1883-1893; DOI: https://doi.org/10.1124/dmd.111.043901
Yasuda, Kaori
- You have accessComparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human LiverKaori Yasuda, Shinichi Ikushiro, Shuto Wakayama, Toshimasa Itoh, Keiko Yamamoto, Masaki Kamakura, Eiji Munetsuna, Miho Ohta and Toshiyuki SakakiDrug Metabolism and Disposition October 2012, 40 (10) 1917-1926; DOI: https://doi.org/10.1124/dmd.112.045906
Yee, Vivien C.
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Yin, Taijun
- You have accessBreast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of GenisteinZhen Yang, Wei Zhu, Song Gao, Taijun Yin, Wen Jiang and Ming HuDrug Metabolism and Disposition October 2012, 40 (10) 1883-1893; DOI: https://doi.org/10.1124/dmd.111.043901
You, Tiangeng
- You have accessMechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic CharacteristicsChunying Gao, Hongjian Zhang, Zitao Guo, Tiangeng You, Xiaoyan Chen and Dafang ZhongDrug Metabolism and Disposition October 2012, 40 (10) 2009-2020; DOI: https://doi.org/10.1124/dmd.112.047183
Z
Zeitlinger, Markus
- You have accessAbsolute Oral Bioavailability and Metabolic Turnover of β-Sitosterol in Healthy SubjectsGuus Duchateau, Brett Cochrane, Sam Windebank, Justyna Herudzinska, Davindera Sanghera, Angela Burian, Markus Müller, Markus Zeitlinger and Graham LappinDrug Metabolism and Disposition October 2012, 40 (10) 2026-2030; DOI: https://doi.org/10.1124/dmd.112.046623
Zhang, Hongbo
- You have accessHuman UDP-Glucuronosyltransferase Expression in Insect Cells: Ratio of Active to Inactive Recombinant Proteins and the Effects of a C-Terminal His-Tag on Glucuronidation KineticsHongbo Zhang, Anne-Sisko Patana, Peter I. Mackenzie, Shinichi Ikushiro, Adrian Goldman and Moshe FinelDrug Metabolism and Disposition October 2012, 40 (10) 1935-1944; DOI: https://doi.org/10.1124/dmd.112.046086
Zhang, Hongjian
- You have accessMechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic CharacteristicsChunying Gao, Hongjian Zhang, Zitao Guo, Tiangeng You, Xiaoyan Chen and Dafang ZhongDrug Metabolism and Disposition October 2012, 40 (10) 2009-2020; DOI: https://doi.org/10.1124/dmd.112.047183
Zhang, Jianping
- You have accessHuman Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype CorrelationYuan Ji, Kendra K. S. Nordgren, Yubo Chai, Scott J. Hebbring, Gregory D. Jenkins, Ryan P. Abo, Yi Peng, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Xiaoshan Chai, Jianping Zhang, Brooke L. Fridley, Vivien C. Yee, Eric D. Wieben and Richard M. WeinshilboumDrug Metabolism and Disposition October 2012, 40 (10) 1984-1992; DOI: https://doi.org/10.1124/dmd.112.046953
Zhang, Jingwei
- You have accessKey Role of Nuclear Factor-κB in the Cellular Pharmacokinetics of Adriamycin in MCF-7/Adr Cells: The Potential Mechanism for Synergy with 20(S)-Ginsenoside Rh2Jingwei Zhang, Meng Lu, Fang Zhou, Haopeng Sun, Gang Hao, Xiaolan Wu and Guangji WangDrug Metabolism and Disposition October 2012, 40 (10) 1900-1908; DOI: https://doi.org/10.1124/dmd.112.045187
Zhang, Wei
- You have accessThe Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, KetoconazoleMosun A. Ayan-Oshodi, Brian A. Willis, William F. Annes, Stephen L. Lowe, Stuart Friedrich, Amparo de la Peña, Wei Zhang, Thomas Brown, Stephen D. Wise and Stephen D. HallDrug Metabolism and Disposition October 2012, 40 (10) 1945-1952; DOI: https://doi.org/10.1124/dmd.112.046060
Zhong, Dafang
- You have accessIn Vitro Studies on the Oxidative Metabolism of 20(S)-Ginsenoside Rh2 in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes, and Human Liver S9Liang Li, Xiaoyan Chen, Jialan Zhou and Dafang ZhongDrug Metabolism and Disposition October 2012, 40 (10) 2041-2053; DOI: https://doi.org/10.1124/dmd.112.046995
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Zhou, Fang
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