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Commentary: Theoretical Predictions of Flow Effects on Intestinal and Systemic Availability in Physiologically Based Pharmacokinetic Intestine Models: The Traditional Model, Segregated Flow Model, and QGut Model

K. Sandy Pang and Edwin C. Y. Chow
Drug Metabolism and Disposition October 2012, 40 (10) 1869-1877; DOI: https://doi.org/10.1124/dmd.112.045872

Article Information

vol. 40 no. 10 1869-1877
DOI 
https://doi.org/10.1124/dmd.112.045872
PubMed 
22745334
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 30, 2012
  • Accepted June 27, 2012
  • Published online September 17, 2012.

Article Versions

Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. K. Sandy Pang, and
  2. Edwin C. Y. Chow
  1. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
  1. Address correspondence to:
    Dr. K. Sandy Pang, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, Canada M5S 3M2. E-mail: ks.pang{at}utoronto.ca
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INTESTINAL FLOW MODELS IN PBPK MODELING

K. Sandy Pang and Edwin C. Y. Chow
Drug Metabolism and Disposition October 1, 2012, 40 (10) 1869-1877; DOI: https://doi.org/10.1124/dmd.112.045872
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