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Research ArticleArticle

Microdialysis Evaluation of Clozapine and N-Desmethylclozapine Pharmacokinetics in Rat Brain

Thomas I. F. H. Cremers, Gunnar Flik, Corry Hofland and Robert E. Stratford Jr.
Drug Metabolism and Disposition October 2012, 40 (10) 1909-1916; DOI: https://doi.org/10.1124/dmd.112.045682
Thomas I. F. H. Cremers
Brains On-Line, South San Francisco, California (T.I.F.H.C.); Department of Biomonitoring and Sensoring, Pharmacy, University of Groningen, Groningen, The Netherlands (G.F., C.H.); and Department of Basic Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, New Orleans, Louisiana (R.E.S.)
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Gunnar Flik
Brains On-Line, South San Francisco, California (T.I.F.H.C.); Department of Biomonitoring and Sensoring, Pharmacy, University of Groningen, Groningen, The Netherlands (G.F., C.H.); and Department of Basic Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, New Orleans, Louisiana (R.E.S.)
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Corry Hofland
Brains On-Line, South San Francisco, California (T.I.F.H.C.); Department of Biomonitoring and Sensoring, Pharmacy, University of Groningen, Groningen, The Netherlands (G.F., C.H.); and Department of Basic Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, New Orleans, Louisiana (R.E.S.)
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Robert E. Stratford Jr.
Brains On-Line, South San Francisco, California (T.I.F.H.C.); Department of Biomonitoring and Sensoring, Pharmacy, University of Groningen, Groningen, The Netherlands (G.F., C.H.); and Department of Basic Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, New Orleans, Louisiana (R.E.S.)
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Article Information

vol. 40 no. 10 1909-1916
DOI 
https://doi.org/10.1124/dmd.112.045682
PubMed 
22736307

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 12, 2012
  • Accepted June 26, 2012
  • Published online September 17, 2012.

Article Versions

  • Earlier version (June 26, 2012 - 11:42).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Thomas I. F. H. Cremers,
  2. Gunnar Flik,
  3. Corry Hofland, and
  4. Robert E. Stratford Jr.
  1. Brains On-Line, South San Francisco, California (T.I.F.H.C.); Department of Biomonitoring and Sensoring, Pharmacy, University of Groningen, Groningen, The Netherlands (G.F., C.H.); and Department of Basic Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, New Orleans, Louisiana (R.E.S.)
  1. Address correspondence to:
    R.E. Stratford, Jr., Department of Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, New Orleans, LA 70125. E-mail: rstratfo{at}xula.edu
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Drug Metabolism and Disposition: 40 (10)
Drug Metabolism and Disposition
Vol. 40, Issue 10
1 Oct 2012
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Research ArticleArticle

CLOZAPINE AND N-DESMETHYLCLOZAPINE BRAIN PHARMACOKINETICS

Thomas I. F. H. Cremers, Gunnar Flik, Corry Hofland and Robert E. Stratford
Drug Metabolism and Disposition October 1, 2012, 40 (10) 1909-1916; DOI: https://doi.org/10.1124/dmd.112.045682

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Research ArticleArticle

CLOZAPINE AND N-DESMETHYLCLOZAPINE BRAIN PHARMACOKINETICS

Thomas I. F. H. Cremers, Gunnar Flik, Corry Hofland and Robert E. Stratford
Drug Metabolism and Disposition October 1, 2012, 40 (10) 1909-1916; DOI: https://doi.org/10.1124/dmd.112.045682
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