Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (Y.J., K.K.S.N., Y.C., S.J.H., R.P.A., L.L.P., I.M., X.C., J.Z., R.M.W.), Division of Biomedical Statistical and Informatics, Department of Health Sciences Research (G.D.J., B.L.F.), and Department of Biochemistry and Molecular Biology (B.W.E., E.D.W.), Mayo Clinic, Rochester, Minnesota; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio (Y.P., V.C.Y.); and College of Pharmacy, Jinan University, Guangzhou, Peoples Republic of China (J.Z.)